| activation of mapk activity | GO:0000187 | 45 | 0.985 | |
| positive regulation of map kinase activity | GO:0043406 | 80 | 0.960 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.939 | Human |
| regulation of mapk cascade | GO:0043408 | 262 | 0.933 | Human Mouse Rat Fly |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.931 | Human Rat |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.926 | Human |
| basement membrane organization | GO:0071711 | 3 | 0.914 | |
| regulation of map kinase activity | GO:0043405 | 108 | 0.909 | Rat |
| hyperosmotic response | GO:0006972 | 4 | 0.907 | |
| activation of protein kinase activity | GO:0032147 | 90 | 0.874 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.865 | Rat |
| regulation of transferase activity | GO:0051338 | 355 | 0.854 | Human Rat |
| melanin metabolic process | GO:0006582 | 1 | 0.852 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.850 | Human |
| regulation of stress activated mapk cascade | GO:0032872 | 84 | 0.835 | Human Mouse Rat Fly |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 119 | 0.831 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 60 | 0.816 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.811 | Human |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.810 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.809 | Human Mouse Rat Fly |
| collateral sprouting | GO:0048668 | 2 | 0.774 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.752 | Human |
| positive regulation of jnk cascade | GO:0046330 | 52 | 0.746 | |
| somitogenesis | GO:0001756 | 2 | 0.744 | |
| secondary metabolic process | GO:0019748 | 17 | 0.707 | |
| innate immune response | GO:0045087 | 178 | 0.700 | |
| regulation of jnk cascade | GO:0046328 | 73 | 0.696 | Human Mouse Rat Fly |
| regulation of kinase activity | GO:0043549 | 314 | 0.695 | Human Rat |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.695 | |
| jnk cascade | GO:0007254 | 80 | 0.682 | Human Mouse Rat Fly |
| positive regulation of jun kinase activity | GO:0043507 | 23 | 0.655 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.649 | Mouse Fly |
| positive regulation of autophagy | GO:0010508 | 24 | 0.642 | |
| activation of jun kinase activity | GO:0007257 | 7 | 0.638 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.637 | |
| peptidyl threonine phosphorylation | GO:0018107 | 41 | 0.625 | |
| positive regulation of stress activated protein kinase signaling cascade | GO:0070304 | 61 | 0.612 | |
| mapk cascade | GO:0000165 | 288 | 0.587 | Human Mouse Rat Fly |
| response to radiation | GO:0009314 | 151 | 0.584 | |
| engulfment of apoptotic cell | GO:0043652 | 2 | 0.561 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 94 | 0.543 | Human Mouse Rat Fly |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.540 | |
| regulation of stress activated protein kinase signaling cascade | GO:0070302 | 85 | 0.512 | Human Mouse Rat Fly |
| membrane organization | GO:0061024 | 292 | 0.466 | |
| nervous system development | GO:0007399 | 293 | 0.464 | Fly |
| response to metal ion | GO:0010038 | 84 | 0.448 | |
| cell projection organization | GO:0030030 | 252 | 0.443 | Fly |
| response to abiotic stimulus | GO:0009628 | 336 | 0.442 | |
| lipid homeostasis | GO:0055088 | 39 | 0.438 | |
| response to nitric oxide | GO:0071731 | 4 | 0.437 | |
| chemical homeostasis | GO:0048878 | 306 | 0.403 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.380 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.372 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.371 | Fly |
| positive regulation of neuron death | GO:1901216 | 14 | 0.364 | |
| regulation of jun kinase activity | GO:0043506 | 27 | 0.363 | Rat |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.363 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.360 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.359 | |
| cellular response to inorganic substance | GO:0071241 | 45 | 0.358 | |
| segmentation | GO:0035282 | 4 | 0.352 | |
| positive regulation of neuron apoptotic process | GO:0043525 | 8 | 0.350 | |
| defense response | GO:0006952 | 315 | 0.340 | |
| epithelium development | GO:0060429 | 227 | 0.339 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.332 | |
| neuron apoptotic process | GO:0051402 | 39 | 0.328 | |
| response to axon injury | GO:0048678 | 1 | 0.326 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.322 | |
| cellular response to arsenic containing substance | GO:0071243 | 4 | 0.314 | |
| amine metabolic process | GO:0009308 | 44 | 0.313 | |
| regulation of microtubule polymerization | GO:0031113 | 12 | 0.304 | |
| regulation of autophagy | GO:0010506 | 52 | 0.304 | |
| phenol containing compound metabolic process | GO:0018958 | 12 | 0.300 | |
| cellular response to metal ion | GO:0071248 | 43 | 0.293 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.291 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.290 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.283 | |
| autophagy | GO:0006914 | 88 | 0.281 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.281 | |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.278 | |
| response to light stimulus | GO:0009416 | 87 | 0.277 | |
| histone modification | GO:0016570 | 251 | 0.264 | |
| basement membrane disassembly | GO:0034769 | 2 | 0.262 | |
| stress activated mapk cascade | GO:0051403 | 93 | 0.259 | Human Mouse Rat Fly |
| generation of neurons | GO:0048699 | 152 | 0.259 | Fly |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.253 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 57 | 0.251 | Rat |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.249 | |
| wound healing | GO:0042060 | 115 | 0.247 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.244 | Rat |
| cell projection morphogenesis | GO:0048858 | 129 | 0.242 | Fly |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.242 | |
| actin filament based process | GO:0030029 | 224 | 0.231 | |
| cell growth | GO:0016049 | 160 | 0.230 | |
| response to wounding | GO:0009611 | 168 | 0.225 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.225 | |
| response to uv | GO:0009411 | 73 | 0.222 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.221 | |
| immune response | GO:0006955 | 307 | 0.216 | |
| neuron differentiation | GO:0030182 | 138 | 0.213 | Fly |
| developmental cell growth | GO:0048588 | 18 | 0.210 | |
| cellular response to mechanical stimulus | GO:0071260 | 39 | 0.204 | |
| post embryonic development | GO:0009791 | 2 | 0.197 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.195 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.194 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.193 | |
| cell morphogenesis | GO:0000902 | 296 | 0.193 | Fly |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.191 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.184 | |
| cellular response to cadmium ion | GO:0071276 | 8 | 0.183 | |
| growth | GO:0040007 | 202 | 0.182 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.180 | |
| response to heat | GO:0009408 | 21 | 0.179 | |
| regulation of determination of dorsal identity | GO:2000015 | 2 | 0.177 | |
| lamellipodium organization | GO:0097581 | 30 | 0.175 | |
| dna replication | GO:0006260 | 116 | 0.174 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.173 | |
| neuron projection development | GO:0031175 | 106 | 0.173 | Fly |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.165 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.165 | Fly |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.163 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.161 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.159 | |
| actin filament organization | GO:0007015 | 128 | 0.159 | |
| endocytosis | GO:0006897 | 159 | 0.158 | |
| peptidyl serine modification | GO:0018209 | 106 | 0.156 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.156 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.153 | |
| acylglycerol homeostasis | GO:0055090 | 14 | 0.148 | |
| extracellular structure organization | GO:0043062 | 41 | 0.146 | |
| cell development | GO:0048468 | 328 | 0.146 | Fly |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.145 | Rat |
| locomotory behavior | GO:0007626 | 1 | 0.144 | |
| mating | GO:0007618 | 1 | 0.140 | |
| neuron projection regeneration | GO:0031102 | 1 | 0.140 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.139 | |
| chromatin modification | GO:0016568 | 298 | 0.139 | |
| carbohydrate homeostasis | GO:0033500 | 31 | 0.138 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.136 | |
| response to temperature stimulus | GO:0009266 | 22 | 0.135 | |
| neurogenesis | GO:0022008 | 169 | 0.134 | Fly |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.132 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.132 | Human Mouse Rat Fly |
| axon regeneration | GO:0031103 | 1 | 0.131 | |
| associative learning | GO:0008306 | 1 | 0.129 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.129 | Rat |
| system process | GO:0003008 | 349 | 0.128 | |
| dna geometric change | GO:0032392 | 32 | 0.123 | |
| glutamate receptor signaling pathway | GO:0007215 | 23 | 0.121 | |
| regulation of neuron death | GO:1901214 | 56 | 0.120 | |
| phagocytosis engulfment | GO:0006911 | 7 | 0.120 | |
| response to cytokine | GO:0034097 | 232 | 0.120 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.119 | Mouse Rat |
| visual learning | GO:0008542 | 1 | 0.118 | |
| axon cargo transport | GO:0008088 | 2 | 0.117 | Fly |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.115 | |
| response to inorganic substance | GO:0010035 | 127 | 0.115 | |
| actin filament bundle assembly | GO:0051017 | 54 | 0.114 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.114 | |
| neuron death | GO:0070997 | 65 | 0.112 | |
| regulation of cell migration | GO:0030334 | 289 | 0.111 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.110 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.110 | |
| apoptotic cell clearance | GO:0043277 | 12 | 0.109 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.109 | |
| negative regulation of jun kinase activity | GO:0043508 | 4 | 0.108 | Rat |
| response to osmotic stress | GO:0006970 | 17 | 0.108 | |
| microtubule based process | GO:0007017 | 210 | 0.106 | Fly |
| neuron projection morphogenesis | GO:0048812 | 50 | 0.103 | Fly |
| activation of jnkk activity | GO:0007256 | 1 | 0.102 | |
| dna repair | GO:0006281 | 198 | 0.101 | |
| transmembrane transport | GO:0055085 | 399 | 0.101 | |
| taxis | GO:0042330 | 157 | 0.098 | |
| regulation of cell motility | GO:2000145 | 299 | 0.097 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.097 | Mouse Rat |
| lamellipodium assembly | GO:0030032 | 26 | 0.097 | |
| cellular component disassembly | GO:0022411 | 92 | 0.096 | |
| positive regulation of cellular component movement | GO:0051272 | 181 | 0.095 | |
| extracellular matrix disassembly | GO:0022617 | 16 | 0.093 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.092 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.092 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.091 | |
| pigment metabolic process | GO:0042440 | 16 | 0.090 | |
| regulation of neuron apoptotic process | GO:0043523 | 35 | 0.089 | |
| neuron development | GO:0048666 | 113 | 0.088 | Fly |
| gtp catabolic process | GO:0006184 | 237 | 0.088 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.086 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.086 | |
| double strand break repair | GO:0006302 | 101 | 0.084 | |
| memory | GO:0007613 | 3 | 0.084 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 4 | 0.083 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.083 | |
| chromatin organization | GO:0006325 | 351 | 0.083 | |
| regionalization | GO:0003002 | 29 | 0.082 | |
| peptidyl threonine modification | GO:0018210 | 45 | 0.080 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.079 | |
| ionotropic glutamate receptor signaling pathway | GO:0035235 | 16 | 0.078 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.078 | |
| response to mechanical stimulus | GO:0009612 | 51 | 0.077 | |
| activation of mapkk activity | GO:0000186 | 18 | 0.077 | |
| positive regulation of cell motility | GO:2000147 | 177 | 0.077 | |
| response to growth factor | GO:0070848 | 205 | 0.076 | |
| cell projection assembly | GO:0030031 | 126 | 0.076 | |
| chemotaxis | GO:0006935 | 157 | 0.075 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.074 | |
| regulation of excitatory postsynaptic membrane potential | GO:0060079 | 1 | 0.073 | |
| axonogenesis | GO:0007409 | 31 | 0.073 | |
| cell morphogenesis involved in neuron differentiation | GO:0048667 | 44 | 0.073 | |
| developmental growth involved in morphogenesis | GO:0060560 | 23 | 0.072 | |
| sister chromatid segregation | GO:0000819 | 54 | 0.072 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.072 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.072 | |
| regulation of synaptic plasticity | GO:0048167 | 3 | 0.071 | |
| regulation of protein polymerization | GO:0032271 | 63 | 0.071 | |
| long term memory | GO:0007616 | 2 | 0.071 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.071 | |
| filopodium assembly | GO:0046847 | 18 | 0.067 | |
| regulation of ion transmembrane transport | GO:0034765 | 132 | 0.067 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.065 | |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 85 | 0.065 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 108 | 0.064 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.064 | |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.063 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.063 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.063 | Rat |
| axon extension | GO:0048675 | 13 | 0.063 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.063 | Rat |
| regulation of ion transport | GO:0043269 | 189 | 0.062 | |
| response to cadmium ion | GO:0046686 | 10 | 0.062 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.062 | |
| regeneration | GO:0031099 | 4 | 0.062 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.061 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.061 | |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.060 | |
| adult locomotory behavior | GO:0008344 | 1 | 0.059 | |
| regulation of binding | GO:0051098 | 111 | 0.059 | |
| actin filament bundle organization | GO:0061572 | 54 | 0.059 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.058 | Mouse Rat |
| neurological system process | GO:0050877 | 163 | 0.057 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.057 | |
| cellular response to carbohydrate stimulus | GO:0071322 | 11 | 0.057 | |
| positive regulation of cell migration | GO:0030335 | 172 | 0.057 | |
| regulation of metal ion transport | GO:0010959 | 120 | 0.056 | |
| triglyceride homeostasis | GO:0070328 | 14 | 0.056 | |
| regulation of protein processing | GO:0070613 | 150 | 0.056 | |
| axon development | GO:0061564 | 34 | 0.056 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.056 | |
| regulation of microtubule polymerization or depolymerization | GO:0031110 | 27 | 0.056 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.055 | |
| ion homeostasis | GO:0050801 | 230 | 0.055 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.055 | |
| organelle fission | GO:0048285 | 149 | 0.053 | |
| response to carbohydrate | GO:0009743 | 21 | 0.052 | |
| calcium ion homeostasis | GO:0055074 | 122 | 0.051 | |
| lipid metabolic process | GO:0006629 | 381 | 0.051 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.051 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.050 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.050 | Rat |
| microtubule based movement | GO:0007018 | 32 | 0.049 | Fly |
| regulation of transmembrane transport | GO:0034762 | 139 | 0.048 | |
| female gamete generation | GO:0007292 | 2 | 0.048 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.048 | Rat |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.048 | |
| motor neuron axon guidance | GO:0008045 | 2 | 0.048 | |
| neurotransmitter secretion | GO:0007269 | 4 | 0.048 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.047 | |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.047 | |
| neuron projection extension | GO:1990138 | 14 | 0.046 | |
| microtubule polymerization or depolymerization | GO:0031109 | 37 | 0.046 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.046 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.046 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.045 | |
| chordate embryonic development | GO:0043009 | 34 | 0.045 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.045 | |
| peripheral nervous system development | GO:0007422 | 2 | 0.045 | |
| metal ion transport | GO:0030001 | 272 | 0.045 | |
| positive regulation of determination of dorsal identity | GO:2000017 | 1 | 0.044 | |
| behavior | GO:0007610 | 112 | 0.044 | |
| lung alveolus development | GO:0048286 | 4 | 0.044 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.044 | Rat |
| mitotic sister chromatid segregation | GO:0000070 | 53 | 0.044 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.044 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.043 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.043 | Rat |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.043 | |
| gtp metabolic process | GO:0046039 | 239 | 0.042 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.042 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.042 | |
| regulation of protein localization | GO:0032880 | 296 | 0.042 | |
| somite development | GO:0061053 | 7 | 0.041 | |
| nuclear division | GO:0000280 | 128 | 0.041 | |
| chromosome segregation | GO:0007059 | 114 | 0.041 | |
| determination of dorsal ventral asymmetry | GO:0048262 | 4 | 0.041 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.041 | |
| chromosome separation | GO:0051304 | 23 | 0.041 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.040 | Rat |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.040 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.040 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.040 | |
| pattern specification process | GO:0007389 | 43 | 0.040 | |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.040 | Rat |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 94 | 0.039 | |
| single organism membrane organization | GO:0044802 | 268 | 0.039 | |
| phagocytosis | GO:0006909 | 42 | 0.039 | |
| endodermal cell fate specification | GO:0001714 | 4 | 0.038 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.038 | |
| regulation of neuron differentiation | GO:0045664 | 70 | 0.038 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.038 | |
| visual behavior | GO:0007632 | 2 | 0.036 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.036 | |
| protein polymerization | GO:0051258 | 71 | 0.036 | |
| inorganic cation transmembrane transport | GO:0098662 | 194 | 0.036 | |
| rho protein signal transduction | GO:0007266 | 26 | 0.036 | |
| secretion by cell | GO:0032940 | 226 | 0.036 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.035 | |
| organic anion transport | GO:0015711 | 103 | 0.035 | |
| protein ubiquitination | GO:0016567 | 314 | 0.034 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.034 | |
| regulation of growth | GO:0040008 | 165 | 0.034 | |
| regulation of cell growth | GO:0001558 | 135 | 0.034 | |
| alcohol metabolic process | GO:0006066 | 114 | 0.034 | |
| leukocyte activation | GO:0045321 | 164 | 0.034 | |
| microtubule polymerization | GO:0046785 | 18 | 0.034 | |
| protein maturation | GO:0051604 | 233 | 0.033 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 24 | 0.033 | |
| positive regulation of cytoskeleton organization | GO:0051495 | 83 | 0.033 | |
| regulation of receptor activity | GO:0010469 | 47 | 0.033 | |
| actin filament based movement | GO:0030048 | 17 | 0.033 | |
| regulation of calcium ion transport | GO:0051924 | 79 | 0.032 | |
| regulation of locomotion | GO:0040012 | 329 | 0.032 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.032 | |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.031 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.031 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.031 | |
| multicellular organismal response to stress | GO:0033555 | 1 | 0.031 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 76 | 0.031 | |
| inorganic ion transmembrane transport | GO:0098660 | 231 | 0.030 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.030 | |
| vasculature development | GO:0001944 | 181 | 0.030 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.030 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.030 | |
| regulation of neuronal synaptic plasticity | GO:0048168 | 1 | 0.030 | |
| protein oligomerization | GO:0051259 | 173 | 0.030 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.030 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.030 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.030 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.030 | |
| regulation of protein binding | GO:0043393 | 66 | 0.030 | |
| regulation of axon guidance | GO:1902667 | 3 | 0.029 | |
| regulation of protein transport | GO:0051223 | 213 | 0.029 | |
| glial cell migration | GO:0008347 | 4 | 0.029 | |
| protein localization to membrane | GO:0072657 | 160 | 0.029 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.029 | |
| regulation of endothelial cell proliferation | GO:0001936 | 56 | 0.029 | |
| developmental growth | GO:0048589 | 48 | 0.029 | |
| protein deacetylation | GO:0006476 | 38 | 0.029 | |
| establishment of vesicle localization | GO:0051650 | 23 | 0.029 | Fly |
| erbb signaling pathway | GO:0038127 | 44 | 0.029 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.028 | Mouse Rat |
| dna conformation change | GO:0071103 | 113 | 0.028 | |
| embryo development | GO:0009790 | 123 | 0.028 | |
| regulation of epidermal growth factor activated receptor activity | GO:0007176 | 14 | 0.028 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.028 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.028 | |
| cellular response to hydrogen peroxide | GO:0070301 | 37 | 0.028 | |
| response to hormone | GO:0009725 | 175 | 0.028 | |
| single organism cellular localization | GO:1902580 | 332 | 0.028 | |
| retina vasculature morphogenesis in camera type eye | GO:0061299 | 3 | 0.028 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.027 | |
| aging | GO:0007568 | 66 | 0.027 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.027 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.026 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.026 | |
| response to molecule of bacterial origin | GO:0002237 | 82 | 0.026 | |
| fear response | GO:0042596 | 0 | 0.026 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.026 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.026 | |
| response to oxidative stress | GO:0006979 | 121 | 0.026 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.026 | |
| calcium ion transmembrane transport | GO:0070588 | 76 | 0.026 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.025 | |
| response to hydrogen peroxide | GO:0042542 | 40 | 0.025 | |
| regulation of cytokine production | GO:0001817 | 232 | 0.025 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.025 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 72 | 0.025 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.025 | |
| cellular response to lipid | GO:0071396 | 127 | 0.025 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.025 | |
| regulation of immune response | GO:0050776 | 201 | 0.025 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.025 | |
| cellular calcium ion homeostasis | GO:0006874 | 117 | 0.025 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.025 | |
| cation homeostasis | GO:0055080 | 189 | 0.025 | |
| behavioral defense response | GO:0002209 | 0 | 0.025 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.025 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.024 | |
| transcription elongation from rna polymerase ii promoter | GO:0006368 | 18 | 0.024 | |
| response to ionizing radiation | GO:0010212 | 65 | 0.024 | |
| cell junction assembly | GO:0034329 | 67 | 0.023 | |
| epithelial cell proliferation | GO:0050673 | 128 | 0.023 | |
| cytokine production | GO:0001816 | 247 | 0.023 | |
| regulation of postsynaptic membrane potential | GO:0060078 | 1 | 0.023 | |
| peptidyl lysine modification | GO:0018205 | 144 | 0.023 | |
| cation transmembrane transport | GO:0098655 | 238 | 0.023 | |
| regulation of transmembrane transporter activity | GO:0022898 | 74 | 0.023 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 99 | 0.023 | |
| muscle cell fate commitment | GO:0042693 | 4 | 0.023 | |
| regulation of membrane potential | GO:0042391 | 95 | 0.023 | |
| positive regulation of protein complex assembly | GO:0031334 | 86 | 0.023 | |
| regulation of neurotransmitter secretion | GO:0046928 | 3 | 0.022 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.022 | |
| sensory perception | GO:0007600 | 103 | 0.022 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.022 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.022 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.022 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.022 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.022 | |
| single organismal cell cell adhesion | GO:0016337 | 148 | 0.022 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 116 | 0.022 | |
| divalent inorganic cation transport | GO:0072511 | 158 | 0.022 | |
| determination of dorsal identity | GO:0048263 | 4 | 0.022 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.022 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.022 | |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.022 | |
| establishment of organelle localization | GO:0051656 | 59 | 0.021 | Fly |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.021 | |
| cellular homeostasis | GO:0019725 | 196 | 0.021 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.021 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.021 | |
| neuron neuron synaptic transmission | GO:0007270 | 6 | 0.021 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.021 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.021 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.021 | |
| response to lipopolysaccharide | GO:0032496 | 70 | 0.021 | |
| convergent extension | GO:0060026 | 1 | 0.021 | |
| regulation of viral process | GO:0050792 | 103 | 0.021 | |
| phospholipid metabolic process | GO:0006644 | 99 | 0.021 | |
| regulation of dna templated transcription elongation | GO:0032784 | 23 | 0.021 | |
| microtubule based transport | GO:0010970 | 21 | 0.021 | Fly |
| regulation of secretion by cell | GO:1903530 | 177 | 0.021 | |
| atp metabolic process | GO:0046034 | 176 | 0.021 | |
| jun phosphorylation | GO:0007258 | 28 | 0.020 | Mouse Rat |
| regulation of erbb signaling pathway | GO:1901184 | 27 | 0.020 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 52 | 0.020 | |
| purine nucleotide biosynthetic process | GO:0006164 | 84 | 0.020 | |
| regulation of rho protein signal transduction | GO:0035023 | 79 | 0.020 | |
| dephosphorylation | GO:0016311 | 209 | 0.020 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.020 | |
| endosomal transport | GO:0016197 | 129 | 0.020 | |
| regulation of axon extension involved in axon guidance | GO:0048841 | 2 | 0.020 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.020 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.020 | |
| receptor metabolic process | GO:0043112 | 81 | 0.019 | |
| positive regulation of transport | GO:0051050 | 336 | 0.019 | |
| protein catabolic process | GO:0030163 | 325 | 0.019 | |
| cell activation | GO:0001775 | 213 | 0.019 | |
| negative regulation of map kinase activity | GO:0043407 | 27 | 0.019 | Rat |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.019 | Mouse |
| photoreceptor cell differentiation | GO:0046530 | 2 | 0.019 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.019 | |
| metencephalon development | GO:0022037 | 2 | 0.019 | |
| oogenesis | GO:0048477 | 2 | 0.019 | |
| negative regulation of binding | GO:0051100 | 57 | 0.019 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 60 | 0.019 | |
| glycoprotein biosynthetic process | GO:0009101 | 91 | 0.019 | |
| protein processing | GO:0016485 | 226 | 0.019 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.019 | Mouse |
| cellular response to reactive nitrogen species | GO:1902170 | 2 | 0.019 | |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.018 | |
| tissue morphogenesis | GO:0048729 | 96 | 0.018 | |
| negative regulation of wnt signaling pathway | GO:0030178 | 69 | 0.018 | |
| dna duplex unwinding | GO:0032508 | 30 | 0.018 | |
| circulatory system process | GO:0003013 | 113 | 0.018 | |
| regulation of microtubule cytoskeleton organization | GO:0070507 | 61 | 0.018 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.018 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.018 | |
| cell cycle arrest | GO:0007050 | 71 | 0.018 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.018 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 0.018 | |
| nuclear transport | GO:0051169 | 179 | 0.018 | |
| negative regulation of stress activated mapk cascade | GO:0032873 | 19 | 0.018 | Rat |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.018 | |
| biological adhesion | GO:0022610 | 331 | 0.018 | |
| rna processing | GO:0006396 | 255 | 0.017 | |
| cardiovascular system development | GO:0072358 | 262 | 0.017 | |
| protein acetylation | GO:0006473 | 116 | 0.017 | |
| regulation of protein tyrosine kinase activity | GO:0061097 | 36 | 0.017 | |
