| trna aminoacylation for protein translation | GO:0006418 | 8 | 1.000 | Yeast |
| amino acid activation | GO:0043038 | 12 | 1.000 | Yeast |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.992 | Yeast |
| trna aminoacylation | GO:0043039 | 12 | 0.989 | Yeast |
| small molecule biosynthetic process | GO:0044283 | 157 | 0.906 | |
| ncrna metabolic process | GO:0034660 | 108 | 0.898 | Yeast |
| patterning of blood vessels | GO:0001569 | 2 | 0.815 | |
| one carbon metabolic process | GO:0006730 | 1 | 0.785 | |
| serine family amino acid metabolic process | GO:0009069 | 12 | 0.616 | |
| dicarboxylic acid metabolic process | GO:0043648 | 29 | 0.597 | |
| translation | GO:0006412 | 132 | 0.592 | Yeast Worm |
| blood vessel development | GO:0001568 | 172 | 0.523 | |
| coenzyme metabolic process | GO:0006732 | 65 | 0.463 | |
| alpha amino acid metabolic process | GO:1901605 | 72 | 0.425 | |
| post embryonic development | GO:0009791 | 2 | 0.346 | Worm |
| trna metabolic process | GO:0006399 | 35 | 0.342 | Yeast |
| mitochondrial rna metabolic process | GO:0000959 | 15 | 0.340 | |
| l serine metabolic process | GO:0006563 | 5 | 0.304 | |
| purine nucleobase biosynthetic process | GO:0009113 | 3 | 0.279 | |
| protein folding | GO:0006457 | 38 | 0.217 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.214 | |
| cellular amino acid catabolic process | GO:0009063 | 31 | 0.204 | |
| cellular modified amino acid metabolic process | GO:0006575 | 64 | 0.180 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.177 | |
| regulation of translation | GO:0006417 | 89 | 0.176 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.143 | |
| proline transport | GO:0015824 | 4 | 0.139 | |
| water soluble vitamin metabolic process | GO:0006767 | 6 | 0.134 | |
| carboxylic acid biosynthetic process | GO:0046394 | 97 | 0.132 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.127 | |
| female gamete generation | GO:0007292 | 2 | 0.121 | |
| amide biosynthetic process | GO:0043604 | 15 | 0.119 | |
| hindbrain development | GO:0030902 | 3 | 0.115 | |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.113 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.113 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.112 | |
| cellular amino acid biosynthetic process | GO:0008652 | 30 | 0.109 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.106 | |
| cellular response to hormone stimulus | GO:0032870 | 125 | 0.106 | |
| nucleobase biosynthetic process | GO:0046112 | 4 | 0.097 | |
| serine family amino acid catabolic process | GO:0009071 | 5 | 0.095 | |
| amino acid transmembrane transport | GO:0003333 | 20 | 0.084 | |
| alpha amino acid catabolic process | GO:1901606 | 26 | 0.078 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.077 | |
| response to amino acid | GO:0043200 | 14 | 0.077 | |
| embryo development | GO:0009790 | 123 | 0.072 | Worm |
| oogenesis | GO:0048477 | 2 | 0.071 | |
| glycine metabolic process | GO:0006544 | 4 | 0.071 | |
| rna processing | GO:0006396 | 255 | 0.069 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.069 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.067 | |
| alanine transport | GO:0032328 | 3 | 0.066 | |
| alpha amino acid biosynthetic process | GO:1901607 | 23 | 0.065 | |
| gland development | GO:0048732 | 48 | 0.062 | |
| angiogenesis | GO:0001525 | 147 | 0.060 | |
| mitochondrion organization | GO:0007005 | 156 | 0.058 | |
| purine nucleobase metabolic process | GO:0006144 | 5 | 0.057 | |
| metencephalon development | GO:0022037 | 2 | 0.057 | |
| aspartate family amino acid biosynthetic process | GO:0009067 | 6 | 0.056 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.055 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 34 | 0.054 | Worm |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.054 | |
| system process | GO:0003008 | 349 | 0.054 | |
| circulatory system development | GO:0072359 | 262 | 0.052 | |
| organic anion transport | GO:0015711 | 103 | 0.051 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.049 | |
| amine metabolic process | GO:0009308 | 44 | 0.048 | |
| dna templated transcription termination | GO:0006353 | 3 | 0.047 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.047 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.046 | |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.046 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.046 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.045 | |
| regulation of locomotion | GO:0040012 | 329 | 0.044 | |
| innate immune response | GO:0045087 | 178 | 0.044 | |
| response to peptide hormone | GO:0043434 | 61 | 0.043 | |
| immune response | GO:0006955 | 307 | 0.042 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.041 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.041 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.040 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.039 | |
| reproduction | GO:0000003 | 63 | 0.039 | Worm |
| chloride transmembrane transport | GO:1902476 | 38 | 0.039 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.038 | |
| vasculature development | GO:0001944 | 181 | 0.037 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.036 | Worm |
| maintenance of location | GO:0051235 | 112 | 0.036 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.036 | |
| organic acid catabolic process | GO:0016054 | 71 | 0.035 | |
| pigment biosynthetic process | GO:0046148 | 10 | 0.035 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.035 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.035 | |
| chemical homeostasis | GO:0048878 | 306 | 0.034 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.034 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.033 | |
| regulation of cytokine production | GO:0001817 | 232 | 0.032 | |
| organic acid biosynthetic process | GO:0016053 | 97 | 0.032 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.032 | |
| response to endoplasmic reticulum stress | GO:0034976 | 49 | 0.031 | |
| pyruvate metabolic process | GO:0006090 | 26 | 0.031 | |
| cardiovascular system development | GO:0072358 | 262 | 0.031 | |
| cellular response to starvation | GO:0009267 | 58 | 0.031 | |
| neurological system process | GO:0050877 | 163 | 0.030 | |
| protein refolding | GO:0042026 | 14 | 0.030 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.030 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.029 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.029 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.029 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.029 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.029 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.028 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.028 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.028 | |
| central nervous system development | GO:0007417 | 123 | 0.028 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.028 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.027 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.027 | |
| protein import into nucleus | GO:0006606 | 104 | 0.027 | |
| dna repair | GO:0006281 | 198 | 0.027 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.026 | |
| leukocyte mediated cytotoxicity | GO:0001909 | 27 | 0.026 | |
| trna processing | GO:0008033 | 23 | 0.026 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.026 | |
| cofactor metabolic process | GO:0051186 | 87 | 0.026 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.026 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.025 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.025 | |
| er nucleus signaling pathway | GO:0006984 | 23 | 0.025 | |
| cell development | GO:0048468 | 328 | 0.025 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.025 | |
| blood vessel morphogenesis | GO:0048514 | 162 | 0.024 | |
| endocytosis | GO:0006897 | 159 | 0.024 | |
| hair cycle | GO:0042633 | 28 | 0.024 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.024 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 158 | 0.023 | |
| mrna metabolic process | GO:0016071 | 175 | 0.023 | |
| regulation of syncytium formation by plasma membrane fusion | GO:0060142 | 2 | 0.022 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.022 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.022 | |
| sulfur amino acid transport | GO:0000101 | 2 | 0.022 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.022 | |
| response to cytokine | GO:0034097 | 232 | 0.022 | |
| small molecule catabolic process | GO:0044282 | 92 | 0.022 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.022 | |
| protein catabolic process | GO:0030163 | 325 | 0.022 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.021 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.021 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.021 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.021 | |
| dicarboxylic acid catabolic process | GO:0043649 | 9 | 0.021 | |
| mitochondrial translation | GO:0032543 | 17 | 0.021 | |
| transmembrane transport | GO:0055085 | 399 | 0.021 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.021 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.020 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.020 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.020 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.020 | |
| dephosphorylation | GO:0016311 | 209 | 0.019 | |
| mapk cascade | GO:0000165 | 288 | 0.019 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.019 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.019 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.019 | Worm |
| response to organic cyclic compound | GO:0014070 | 204 | 0.019 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.019 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.019 | |
| atp catabolic process | GO:0006200 | 157 | 0.018 | |
| canonical wnt signaling pathway involved in negative regulation of apoptotic process | GO:0044336 | 2 | 0.018 | |
| positive regulation of interferon gamma production | GO:0032729 | 26 | 0.018 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.018 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.018 | |
| epithelium development | GO:0060429 | 227 | 0.018 | |
| l serine catabolic process | GO:0006565 | 3 | 0.018 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.018 | |
| regeneration | GO:0031099 | 4 | 0.017 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.017 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.017 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.017 | |
| protein oligomerization | GO:0051259 | 173 | 0.017 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.016 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.016 | |
| skin development | GO:0043588 | 76 | 0.016 | |
| regulation of jak stat cascade | GO:0046425 | 44 | 0.016 | |
| response to hormone | GO:0009725 | 175 | 0.016 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.016 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.016 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.016 | |
| protein ubiquitination | GO:0016567 | 314 | 0.016 | |
| biological adhesion | GO:0022610 | 331 | 0.016 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.016 | |
| defense response | GO:0006952 | 315 | 0.016 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.015 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.015 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 109 | 0.015 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.015 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.015 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.015 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.015 | |
| atp metabolic process | GO:0046034 | 176 | 0.015 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.015 | |
| carboxylic acid catabolic process | GO:0046395 | 71 | 0.015 | |
| multicellular organismal reproductive process | GO:0048609 | 40 | 0.015 | |
| regulation of cell motility | GO:2000145 | 299 | 0.015 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.015 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.015 | |
| response to mechanical stimulus | GO:0009612 | 51 | 0.015 | |
| cerebellar cortex development | GO:0021695 | 1 | 0.015 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 78 | 0.014 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.014 | |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.014 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.014 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.014 | |
| arginine transport | GO:0015809 | 2 | 0.014 | |
| cell cycle g1 s phase transition | GO:0044843 | 80 | 0.014 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.014 | |
| memory | GO:0007613 | 3 | 0.014 | |
| response to hypoxia | GO:0001666 | 96 | 0.014 | |
| lymphocyte differentiation | GO:0030098 | 35 | 0.014 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.014 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.013 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.013 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.013 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.013 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.013 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.013 | |
| cytokine production | GO:0001816 | 247 | 0.013 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.013 | |
| cerebellum development | GO:0021549 | 2 | 0.013 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 60 | 0.013 | |
| pigment metabolic process | GO:0042440 | 16 | 0.013 | |
| positive regulation of response to dna damage stimulus | GO:2001022 | 43 | 0.013 | |
| negative regulation of neuron death | GO:1901215 | 32 | 0.013 | |
| meiosis i | GO:0007127 | 4 | 0.013 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.013 | |
| regulation of cell development | GO:0060284 | 161 | 0.013 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.013 | |
| regulation of viral process | GO:0050792 | 103 | 0.013 | |
| response to radiation | GO:0009314 | 151 | 0.013 | |
| response to peptide | GO:1901652 | 65 | 0.013 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.013 | |
| regulation of neuron death | GO:1901214 | 56 | 0.013 | |
| cytokine biosynthetic process | GO:0042089 | 37 | 0.012 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.012 | |
| ossification | GO:0001503 | 121 | 0.012 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.012 | |
| regulation of actin filament length | GO:0030832 | 56 | 0.012 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 125 | 0.012 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 94 | 0.012 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.012 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.012 | |
| hemopoiesis | GO:0030097 | 180 | 0.012 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.012 | |
| compound eye development | GO:0048749 | 1 | 0.012 | |
| cell activation | GO:0001775 | 213 | 0.012 | |
| cation transmembrane transport | GO:0098655 | 238 | 0.012 | |
| response to virus | GO:0009615 | 126 | 0.012 | |
| immune effector process | GO:0002252 | 159 | 0.012 | |
| lipid biosynthetic process | GO:0008610 | 177 | 0.012 | |
| cation transport | GO:0006812 | 331 | 0.012 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.012 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.011 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.011 | |
| nucleobase metabolic process | GO:0009112 | 8 | 0.011 | |
| locomotory behavior | GO:0007626 | 1 | 0.011 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.011 | |
| monosaccharide metabolic process | GO:0005996 | 74 | 0.011 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.011 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.011 | |
| negative regulation of cell migration | GO:0030336 | 102 | 0.011 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.011 | |
| embryonic eye morphogenesis | GO:0048048 | 2 | 0.011 | |
| rna splicing | GO:0008380 | 131 | 0.011 | |
| ncrna processing | GO:0034470 | 83 | 0.011 | |
| response to lipid | GO:0033993 | 206 | 0.011 | |
| modified amino acid transport | GO:0072337 | 11 | 0.011 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.011 | |
| response to extracellular stimulus | GO:0009991 | 85 | 0.011 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.011 | |
| nucleobase containing compound transport | GO:0015931 | 51 | 0.011 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.011 | |
| head development | GO:0060322 | 108 | 0.011 | |
| nucleus localization | GO:0051647 | 1 | 0.011 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.011 | |
| regulation of actin filament based process | GO:0032970 | 141 | 0.011 | |
| carboxylic acid transport | GO:0046942 | 63 | 0.011 | |
| positive regulation of protein polymerization | GO:0032273 | 45 | 0.011 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.010 | |
| cellular response to biotic stimulus | GO:0071216 | 71 | 0.010 | |
| actin polymerization or depolymerization | GO:0008154 | 56 | 0.010 | |
| organic acid transport | GO:0015849 | 65 | 0.010 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.010 | |
| trna transport | GO:0051031 | 1 | 0.010 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.010 | |
| lymphocyte activation | GO:0046649 | 133 | 0.010 | |
| calcium ion transport | GO:0006816 | 147 | 0.010 | |
| response to insulin | GO:0032868 | 45 | 0.010 | |
| cell morphogenesis | GO:0000902 | 296 | 0.010 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.010 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.010 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.010 | |
| glycerol metabolic process | GO:0006071 | 4 | 0.010 | |
| actin filament based process | GO:0030029 | 224 | 0.010 | |