| chromatin organization | GO:0006325 | 351 | 0.989 | |
| chromatin modification | GO:0016568 | 298 | 0.923 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.820 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.410 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.329 | |
| histone modification | GO:0016570 | 251 | 0.325 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.304 | |
| protein ubiquitination | GO:0016567 | 314 | 0.247 | |
| chromatin remodeling | GO:0006338 | 55 | 0.241 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.239 | |
| macromolecule methylation | GO:0043414 | 97 | 0.233 | |
| chromatin assembly | GO:0031497 | 61 | 0.183 | |
| amine metabolic process | GO:0009308 | 44 | 0.179 | |
| protein dna complex subunit organization | GO:0071824 | 80 | 0.162 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.160 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.153 | |
| cell projection organization | GO:0030030 | 252 | 0.151 | |
| histone methylation | GO:0016571 | 60 | 0.137 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.135 | |
| female gamete generation | GO:0007292 | 2 | 0.128 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.127 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.119 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.113 | |
| protein processing | GO:0016485 | 226 | 0.111 | |
| protein localization to organelle | GO:0033365 | 280 | 0.110 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.109 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.106 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.104 | |
| cellular homeostasis | GO:0019725 | 196 | 0.098 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.098 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 81 | 0.092 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.092 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.092 | |
| oocyte development | GO:0048599 | 1 | 0.088 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.086 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.084 | |
| nervous system development | GO:0007399 | 293 | 0.083 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.083 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.081 | |
| ribonucleoprotein complex assembly | GO:0022618 | 78 | 0.078 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.074 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.072 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.071 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.069 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.067 | |
| chromosome segregation | GO:0007059 | 114 | 0.067 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.064 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.063 | |
| central nervous system development | GO:0007417 | 123 | 0.063 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.061 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.058 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.058 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.055 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.052 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.052 | |
| nuclear body organization | GO:0030575 | 4 | 0.051 | |
| response to cytokine | GO:0034097 | 232 | 0.050 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.047 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.047 | |
| cell cell signaling | GO:0007267 | 155 | 0.047 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.046 | |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.045 | |
| protein alkylation | GO:0008213 | 74 | 0.045 | |
| protein modification by small protein removal | GO:0070646 | 92 | 0.044 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.044 | |
| cell morphogenesis | GO:0000902 | 296 | 0.042 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.041 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.040 | |
| double strand break repair | GO:0006302 | 101 | 0.040 | |
| protein maturation | GO:0051604 | 233 | 0.039 | |
| response to hormone | GO:0009725 | 175 | 0.039 | |
| regulation of heart growth | GO:0060420 | 4 | 0.039 | |
| post embryonic development | GO:0009791 | 2 | 0.039 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.037 | |
| cell development | GO:0048468 | 328 | 0.036 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.036 | |
| cell division | GO:0051301 | 168 | 0.036 | |
| nucleosome organization | GO:0034728 | 66 | 0.036 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.036 | |
| secretion | GO:0046903 | 254 | 0.035 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.035 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.033 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.033 | |
| single organism cellular localization | GO:1902580 | 332 | 0.033 | |
| regulation of cell growth | GO:0001558 | 135 | 0.033 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.033 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.032 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.032 | |
| organelle assembly | GO:0070925 | 176 | 0.032 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.032 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.032 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.031 | |
| segmentation | GO:0035282 | 4 | 0.031 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.031 | |
| translation | GO:0006412 | 132 | 0.031 | |
| pml body organization | GO:0030578 | 2 | 0.030 | |
| neurogenesis | GO:0022008 | 169 | 0.030 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.029 | |
| protein targeting | GO:0006605 | 187 | 0.029 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.029 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.029 | |
| gene silencing | GO:0016458 | 49 | 0.029 | |
| oogenesis | GO:0048477 | 2 | 0.029 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.029 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.029 | |
| cell fate commitment | GO:0045165 | 27 | 0.029 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.029 | |
| neuron projection development | GO:0031175 | 106 | 0.028 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.028 | |
| cilium organization | GO:0044782 | 68 | 0.028 | |
| neuron differentiation | GO:0030182 | 138 | 0.028 | |
| regulation of actin filament based process | GO:0032970 | 141 | 0.028 | |
| secretion by cell | GO:0032940 | 226 | 0.027 | |
| histone acetylation | GO:0016573 | 93 | 0.027 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.027 | |
| response to alcohol | GO:0097305 | 64 | 0.027 | |
| single organism membrane organization | GO:0044802 | 268 | 0.027 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.027 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.026 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.026 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.026 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.026 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.026 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.026 | |
| detection of mechanical stimulus involved in sensory perception | GO:0050974 | 1 | 0.026 | |
| maintenance of location | GO:0051235 | 112 | 0.026 | |
| histone exchange | GO:0043486 | 3 | 0.025 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.025 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.025 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.025 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.025 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.025 | |
| positive regulation of cell cycle process | GO:0090068 | 106 | 0.024 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.024 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.023 | |
| positive regulation of protein complex assembly | GO:0031334 | 86 | 0.023 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.023 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.023 | |
| intracellular protein transport | GO:0006886 | 270 | 0.022 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.022 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 125 | 0.022 | |
| positive regulation of dna metabolic process | GO:0051054 | 73 | 0.022 | |
| response to reactive oxygen species | GO:0000302 | 61 | 0.022 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.021 | |
| cellular response to radiation | GO:0071478 | 65 | 0.021 | |
| nuclear division | GO:0000280 | 128 | 0.021 | |
| dna repair | GO:0006281 | 198 | 0.021 | |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.021 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.020 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.020 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.020 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.020 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.020 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.020 | |
| glycerolipid metabolic process | GO:0046486 | 107 | 0.020 | |
| response to inorganic substance | GO:0010035 | 127 | 0.020 | |
| single organism reproductive process | GO:0044702 | 98 | 0.019 | |
| internal peptidyl lysine acetylation | GO:0018393 | 97 | 0.019 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.019 | |
| organelle fission | GO:0048285 | 149 | 0.019 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.019 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.019 | |
| response to oxygen levels | GO:0070482 | 100 | 0.019 | |
| oocyte differentiation | GO:0009994 | 2 | 0.019 | |
| peptidyl lysine acetylation | GO:0018394 | 101 | 0.019 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.019 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.019 | |
| cellular response to hormone stimulus | GO:0032870 | 125 | 0.019 | |
| response to oxidative stress | GO:0006979 | 121 | 0.019 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.019 | |
| chemical homeostasis | GO:0048878 | 306 | 0.019 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.018 | |
| regulation of cardioblast differentiation | GO:0051890 | 4 | 0.018 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.018 | |
| protein import | GO:0017038 | 130 | 0.018 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.018 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.018 | |
| histone arginine methylation | GO:0034969 | 6 | 0.017 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.017 | |
| neuron development | GO:0048666 | 113 | 0.017 | |
| regulation of protein localization | GO:0032880 | 296 | 0.017 | |
| cell cycle arrest | GO:0007050 | 71 | 0.017 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.017 | |
| reproductive process | GO:0022414 | 106 | 0.017 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.017 | |
| protein polymerization | GO:0051258 | 71 | 0.016 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.016 | |
| regulation of protein localization to plasma membrane | GO:1903076 | 40 | 0.016 | |
| regulation of chromatin organization | GO:1902275 | 56 | 0.016 | |
| positive regulation of chromatin modification | GO:1903310 | 30 | 0.016 | |
| sister chromatid segregation | GO:0000819 | 54 | 0.016 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.016 | |
| mating | GO:0007618 | 1 | 0.016 | |
| regulation of protein stability | GO:0031647 | 87 | 0.016 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.016 | |
| dephosphorylation | GO:0016311 | 209 | 0.016 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.015 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.015 | |
| positive regulation of cytoskeleton organization | GO:0051495 | 83 | 0.015 | |
| positive regulation of chromosome organization | GO:2001252 | 41 | 0.015 | |
| endomembrane system organization | GO:0010256 | 196 | 0.015 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.015 | |
| cilium assembly | GO:0042384 | 63 | 0.015 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.015 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.015 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.015 | |
| regulation of defense response | GO:0031347 | 154 | 0.014 | |
| striated muscle cell differentiation | GO:0051146 | 43 | 0.014 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.014 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.014 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.014 | |
| stem cell differentiation | GO:0048863 | 93 | 0.014 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.014 | |
| generation of neurons | GO:0048699 | 152 | 0.014 | |
| hypothalamus development | GO:0021854 | 1 | 0.014 | |
| dna conformation change | GO:0071103 | 113 | 0.014 | |
| embryo development | GO:0009790 | 123 | 0.014 | |
| regulation of protein processing | GO:0070613 | 150 | 0.014 | |
| anterior posterior axis specification embryo | GO:0008595 | 2 | 0.014 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.014 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.014 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.014 | |
| compound eye development | GO:0048749 | 1 | 0.014 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.014 | |
| regulation of dna replication | GO:0006275 | 68 | 0.014 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.014 | |
| dna replication | GO:0006260 | 116 | 0.014 | |
| system process | GO:0003008 | 349 | 0.013 | |
| spermatid differentiation | GO:0048515 | 4 | 0.013 | |
| regulation of viral release from host cell | GO:1902186 | 20 | 0.013 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.013 | |
| response to lipid | GO:0033993 | 206 | 0.013 | |
| locomotory behavior | GO:0007626 | 1 | 0.013 | |
| protein secretion | GO:0009306 | 98 | 0.013 | |
| actin polymerization or depolymerization | GO:0008154 | 56 | 0.013 | |
| interspecies interaction between organisms | GO:0044419 | 156 | 0.013 | |
| regulation of calcium ion transport | GO:0051924 | 79 | 0.013 | |
| zymogen activation | GO:0031638 | 70 | 0.013 | |
| regulation of protein transport | GO:0051223 | 213 | 0.013 | |
| intrinsic apoptotic signaling pathway in response to oxidative stress | GO:0008631 | 21 | 0.013 | |
| ion homeostasis | GO:0050801 | 230 | 0.012 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.012 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.012 | |
| atp metabolic process | GO:0046034 | 176 | 0.012 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.012 | |
| chromatin assembly or disassembly | GO:0006333 | 78 | 0.012 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.012 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.012 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.012 | |
| regulation of chromatin modification | GO:1903308 | 51 | 0.012 | |
| histone h4 acetylation | GO:0043967 | 47 | 0.012 | |
| growth | GO:0040007 | 202 | 0.012 | |
| positive regulation of t cell apoptotic process | GO:0070234 | 4 | 0.012 | |
| meiotic chromosome segregation | GO:0045132 | 4 | 0.012 | |
| gland development | GO:0048732 | 48 | 0.012 | |
| cellular response to decreased oxygen levels | GO:0036294 | 51 | 0.012 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.012 | |
| regulation of translation | GO:0006417 | 89 | 0.011 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.011 | |
| cell projection assembly | GO:0030031 | 126 | 0.011 | |
| dendrite development | GO:0016358 | 24 | 0.011 | |
| regulation of actin filament polymerization | GO:0030833 | 50 | 0.011 | |
| cell growth | GO:0016049 | 160 | 0.011 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.011 | |
| spermatid development | GO:0007286 | 4 | 0.011 | |
| negative regulation of response to external stimulus | GO:0032102 | 83 | 0.011 | |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.011 | |
| regulation of chromosome organization | GO:0033044 | 103 | 0.011 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.011 | |
| protein methylation | GO:0006479 | 74 | 0.011 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.011 | |
| neuron projection morphogenesis | GO:0048812 | 50 | 0.011 | |
| cilium morphogenesis | GO:0060271 | 75 | 0.010 | |
| regionalization | GO:0003002 | 29 | 0.010 | |
| regulation of chromosome segregation | GO:0051983 | 44 | 0.010 | |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 85 | 0.010 | |
| sexual reproduction | GO:0019953 | 37 | 0.010 | |
