| amine metabolic process | GO:0009308 | 44 | 0.347 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.307 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.190 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.147 | |
| protein ubiquitination | GO:0016567 | 314 | 0.135 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.123 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.115 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.104 | |
| dna templated transcription initiation | GO:0006352 | 35 | 0.102 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.100 | |
| small molecule biosynthetic process | GO:0044283 | 157 | 0.099 | |
| lipid metabolic process | GO:0006629 | 381 | 0.099 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.096 | |
| single organism cellular localization | GO:1902580 | 332 | 0.096 | |
| vacuolar transport | GO:0007034 | 34 | 0.093 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.090 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.086 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.081 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.075 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.070 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.068 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.065 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.061 | |
| inner ear morphogenesis | GO:0042472 | 4 | 0.054 | |
| epithelial cell differentiation | GO:0030855 | 141 | 0.052 | |
| response to endoplasmic reticulum stress | GO:0034976 | 49 | 0.052 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.052 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.051 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.051 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.050 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.049 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.047 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.047 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.046 | |
| regulation of secretion | GO:0051046 | 194 | 0.045 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.045 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.044 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.042 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.041 | |
| rab protein signal transduction | GO:0032482 | 4 | 0.040 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.040 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.040 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.040 | |
| endomembrane system organization | GO:0010256 | 196 | 0.039 | |
| regulation of cell projection organization | GO:0031344 | 107 | 0.039 | |
| cell projection organization | GO:0030030 | 252 | 0.038 | |
| membrane organization | GO:0061024 | 292 | 0.038 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.038 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.037 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.037 | |
| dephosphorylation | GO:0016311 | 209 | 0.037 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.036 | |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.036 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.035 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.035 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.035 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.035 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.035 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.034 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.034 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.034 | |
| regulation of vesicle mediated transport | GO:0060627 | 130 | 0.034 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.033 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.033 | |
| endosomal transport | GO:0016197 | 129 | 0.032 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.032 | |
| response to transforming growth factor beta | GO:0071559 | 94 | 0.032 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.032 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.031 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.031 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.031 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.031 | |
| epithelium development | GO:0060429 | 227 | 0.031 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.031 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.031 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.030 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.030 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.030 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.030 | |
| negative regulation of secretion by cell | GO:1903531 | 52 | 0.029 | |
| gtp metabolic process | GO:0046039 | 239 | 0.029 | |
| wound healing | GO:0042060 | 115 | 0.029 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.028 | |
| cell morphogenesis | GO:0000902 | 296 | 0.028 | |
| single organism membrane organization | GO:0044802 | 268 | 0.028 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.028 | |
| regulation of hormone levels | GO:0010817 | 125 | 0.027 | |
| protein catabolic process | GO:0030163 | 325 | 0.027 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.027 | |
| lipid biosynthetic process | GO:0008610 | 177 | 0.026 | |
| response to cytokine | GO:0034097 | 232 | 0.026 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.026 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.025 | |
| regulation of transcription by chromatin organization | GO:0034401 | 1 | 0.025 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.025 | |
| secretion by cell | GO:0032940 | 226 | 0.025 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.025 | |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.025 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.025 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.024 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.024 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 27 | 0.024 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.024 | |
| peptide transport | GO:0015833 | 74 | 0.024 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.023 | |
| actin filament based process | GO:0030029 | 224 | 0.023 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.023 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.023 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.023 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.023 | |
| glycerolipid metabolic process | GO:0046486 | 107 | 0.022 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.022 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.022 | |
| post embryonic development | GO:0009791 | 2 | 0.022 | Mouse |
| growth | GO:0040007 | 202 | 0.022 | |
| neuron differentiation | GO:0030182 | 138 | 0.021 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.021 | |
| microtubule based process | GO:0007017 | 210 | 0.021 | |
| immune response | GO:0006955 | 307 | 0.021 | |
| positive regulation of transport | GO:0051050 | 336 | 0.020 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.020 | |
| positive regulation of secretion by cell | GO:1903532 | 108 | 0.020 | |
| segmentation | GO:0035282 | 4 | 0.020 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.020 | |
| jnk cascade | GO:0007254 | 80 | 0.020 | |
| chromatin modification | GO:0016568 | 298 | 0.020 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.019 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.019 | |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.019 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.019 | |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.019 | |
| methylation | GO:0032259 | 106 | 0.019 | |
| stress activated mapk cascade | GO:0051403 | 93 | 0.019 | |
| intracellular protein transport | GO:0006886 | 270 | 0.019 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.019 | |
| hair cell differentiation | GO:0035315 | 2 | 0.019 | |
| positive regulation of myeloid cell apoptotic process | GO:0033034 | 2 | 0.019 | |
| histone modification | GO:0016570 | 251 | 0.019 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.018 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.018 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.018 | |
| protein localization to organelle | GO:0033365 | 280 | 0.018 | |
| lymphocyte activation | GO:0046649 | 133 | 0.018 | |
| response to peptide hormone | GO:0043434 | 61 | 0.018 | |
| hindbrain development | GO:0030902 | 3 | 0.018 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.018 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.018 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.018 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.017 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.017 | |
| response to oxidative stress | GO:0006979 | 121 | 0.017 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.017 | |
| regulation of chromatin organization | GO:1902275 | 56 | 0.017 | |
| regulation of growth rate | GO:0040009 | 1 | 0.017 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.017 | |
| negative regulation of growth | GO:0045926 | 97 | 0.017 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.017 | |
| positive regulation of phagocytosis engulfment | GO:0060100 | 1 | 0.017 | |
| leukocyte activation | GO:0045321 | 164 | 0.017 | |
| regulation of rab protein signal transduction | GO:0032483 | 39 | 0.017 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 156 | 0.017 | |
| rna processing | GO:0006396 | 255 | 0.017 | |
| positive regulation of immune response | GO:0050778 | 159 | 0.016 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.016 | |
| cellular response to hypoxia | GO:0071456 | 51 | 0.016 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.016 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.016 | |
| response to radiation | GO:0009314 | 151 | 0.016 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.016 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.016 | |
| response to insulin | GO:0032868 | 45 | 0.016 | |
| secretion | GO:0046903 | 254 | 0.016 | |
| amide biosynthetic process | GO:0043604 | 15 | 0.016 | |
| vacuole organization | GO:0007033 | 44 | 0.016 | |
| signal release | GO:0023061 | 70 | 0.015 | |
| regulation of cell activation | GO:0050865 | 125 | 0.015 | |
| neural tube closure | GO:0001843 | 3 | 0.015 | |
| positive regulation of protein complex assembly | GO:0031334 | 86 | 0.015 | |
| regulation of cell division | GO:0051302 | 116 | 0.015 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.015 | |
| nervous system development | GO:0007399 | 293 | 0.015 | |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.015 | |
| response to other organism | GO:0051707 | 261 | 0.015 | |
| chromatin organization | GO:0006325 | 351 | 0.015 | |
| response to wounding | GO:0009611 | 168 | 0.015 | |
| cellular response to glucocorticoid stimulus | GO:0071385 | 4 | 0.015 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.015 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.015 | |
| positive regulation of secretion | GO:0051047 | 116 | 0.015 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.015 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.015 | |
| plasma membrane organization | GO:0007009 | 115 | 0.015 | |
| adaptive immune response | GO:0002250 | 49 | 0.015 | |
| positive regulation of protein ubiquitination | GO:0031398 | 53 | 0.014 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.014 | |
| negative regulation of transport | GO:0051051 | 176 | 0.014 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.014 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.014 | |
| negative regulation of cell growth | GO:0030308 | 83 | 0.014 | |
| golgi vesicle transport | GO:0048193 | 80 | 0.014 | |
| interspecies interaction between organisms | GO:0044419 | 156 | 0.014 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.014 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.013 | |
| regulation of natural killer cell differentiation | GO:0032823 | 2 | 0.013 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.013 | |
| organic acid biosynthetic process | GO:0016053 | 97 | 0.013 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.013 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.013 | |
| cellular response to decreased oxygen levels | GO:0036294 | 51 | 0.013 | |
| protein targeting | GO:0006605 | 187 | 0.013 | |
| tor signaling | GO:0031929 | 39 | 0.013 | |
| regulation of cellular component size | GO:0032535 | 82 | 0.013 | |
| maintenance of location | GO:0051235 | 112 | 0.013 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.013 | |
| negative regulation of secretion | GO:0051048 | 58 | 0.013 | |
| female gamete generation | GO:0007292 | 2 | 0.013 | |
| mapk cascade | GO:0000165 | 288 | 0.013 | |
| regulation of protein stability | GO:0031647 | 87 | 0.013 | |
| microtubule organizing center organization | GO:0031023 | 62 | 0.013 | |
| neuron development | GO:0048666 | 113 | 0.012 | |
| amide transport | GO:0042886 | 76 | 0.012 | |
| vesicle organization | GO:0016050 | 62 | 0.012 | |
| regulation of homeostatic process | GO:0032844 | 121 | 0.012 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.012 | |
| regulation of defense response | GO:0031347 | 154 | 0.012 | |
| response to hormone | GO:0009725 | 175 | 0.012 | |
| regulation of neural precursor cell proliferation | GO:2000177 | 4 | 0.012 | |
| phospholipid metabolic process | GO:0006644 | 99 | 0.012 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.012 | |
| response to uv | GO:0009411 | 73 | 0.012 | |
| morphogenesis of a polarized epithelium | GO:0001738 | 3 | 0.012 | |
| cell activation | GO:0001775 | 213 | 0.012 | |
| fatty acid metabolic process | GO:0006631 | 115 | 0.012 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.012 | |
| t cell differentiation in thymus | GO:0033077 | 4 | 0.012 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.012 | |
| behavioral response to ethanol | GO:0048149 | 2 | 0.012 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.012 | |
| negative regulation of alpha beta t cell activation | GO:0046636 | 3 | 0.012 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.012 | |
| cell growth | GO:0016049 | 160 | 0.011 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.011 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.011 | |
| chemical homeostasis | GO:0048878 | 306 | 0.011 | |
| hormone secretion | GO:0046879 | 65 | 0.011 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.011 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.011 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.011 | |
| organelle assembly | GO:0070925 | 176 | 0.011 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.011 | |
| regulation of meiosis | GO:0040020 | 3 | 0.011 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.011 | |
| cellular response to nutrient levels | GO:0031669 | 69 | 0.011 | |
| syncytium formation by plasma membrane fusion | GO:0000768 | 2 | 0.011 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.011 | |
| mrna metabolic process | GO:0016071 | 175 | 0.011 | |
| peptide secretion | GO:0002790 | 51 | 0.010 | |
| response to peptide | GO:1901652 | 65 | 0.010 | |
| regulation of golgi to plasma membrane protein transport | GO:0042996 | 3 | 0.010 | |
| cellular response to oxygen levels | GO:0071453 | 55 | 0.010 | |
| lipid homeostasis | GO:0055088 | 39 | 0.010 | |
| cell cycle g1 s phase transition | GO:0044843 | 80 | 0.010 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.010 | |
| immune effector process | GO:0002252 | 159 | 0.010 | |
| fatty acid derivative metabolic process | GO:1901568 | 35 | 0.010 | |
| response to hypoxia | GO:0001666 | 96 | 0.010 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.010 | |
| regulation of tor signaling | GO:0032006 | 30 | 0.010 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.010 | |
