| regulation of protein autophosphorylation | GO:0031952 | 15 | 1.000 | |
| telomere capping | GO:0016233 | 5 | 1.000 | Fly |
| double strand break repair | GO:0006302 | 101 | 0.999 | Yeast Mouse |
| dna repair | GO:0006281 | 198 | 0.999 | Yeast Mouse |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.999 | |
| replication fork processing | GO:0031297 | 13 | 0.996 | |
| telomere maintenance via telomere lengthening | GO:0010833 | 9 | 0.989 | |
| nucleotide excision repair | GO:0006289 | 31 | 0.988 | |
| dna geometric change | GO:0032392 | 32 | 0.976 | |
| dna double strand break processing | GO:0000729 | 10 | 0.971 | Yeast |
| double strand break repair via single strand annealing | GO:0045002 | 4 | 0.963 | |
| v d j recombination | GO:0033151 | 3 | 0.959 | |
| g2 dna damage checkpoint | GO:0031572 | 26 | 0.951 | Mouse Fly |
| cell cycle checkpoint | GO:0000075 | 117 | 0.948 | Mouse Fly |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.944 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.922 | |
| isotype switching | GO:0045190 | 3 | 0.921 | |
| double strand break repair via homologous recombination | GO:0000724 | 50 | 0.917 | Yeast |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.898 | |
| g2 m transition of mitotic cell cycle | GO:0000086 | 41 | 0.884 | |
| blastocyst development | GO:0001824 | 3 | 0.881 | |
| signal transduction in response to dna damage | GO:0042770 | 57 | 0.878 | |
| dna damage induced protein phosphorylation | GO:0006975 | 5 | 0.846 | |
| dna conformation change | GO:0071103 | 113 | 0.779 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.761 | |
| somatic recombination of immunoglobulin gene segments | GO:0016447 | 4 | 0.751 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 44 | 0.727 | |
| somatic diversification of immunoglobulins involved in immune response | GO:0002208 | 3 | 0.723 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.715 | |
| organelle fission | GO:0048285 | 149 | 0.712 | Yeast Mouse Worm |
| dna catabolic process exonucleolytic | GO:0000738 | 17 | 0.708 | Yeast |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.695 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.687 | |
| somatic recombination of immunoglobulin genes involved in immune response | GO:0002204 | 3 | 0.680 | |
| meiotic chromosome segregation | GO:0045132 | 4 | 0.677 | Worm |
| response to ionizing radiation | GO:0010212 | 65 | 0.650 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.639 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.638 | Mouse Worm Fly |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.593 | |
| regulation of double strand break repair | GO:2000779 | 22 | 0.576 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.570 | |
| telomere maintenance via telomerase | GO:0007004 | 8 | 0.565 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.546 | Mouse Fly |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.539 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.527 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.525 | Mouse Worm Fly |
| neuromuscular process controlling balance | GO:0050885 | 7 | 0.518 | |
| response to radiation | GO:0009314 | 151 | 0.516 | |
| telomere maintenance | GO:0000723 | 32 | 0.503 | Fly |
| dna catabolic process endonucleolytic | GO:0000737 | 37 | 0.474 | Yeast |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.466 | |
| negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | GO:1902042 | 15 | 0.458 | |
| cell cycle arrest | GO:0007050 | 71 | 0.444 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.440 | |
| chromosome segregation | GO:0007059 | 114 | 0.427 | |
| positive regulation of telomere maintenance | GO:0032206 | 4 | 0.422 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.412 | |
| dna integrity checkpoint | GO:0031570 | 71 | 0.389 | Mouse Fly |
| dna duplex unwinding | GO:0032508 | 30 | 0.386 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.384 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.381 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.377 | Mouse Fly |
| cardiovascular system development | GO:0072358 | 262 | 0.367 | |
| response to gamma radiation | GO:0010332 | 14 | 0.357 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.357 | |
| dna catabolic process | GO:0006308 | 49 | 0.354 | Yeast |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.344 | |
| atp metabolic process | GO:0046034 | 176 | 0.342 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.339 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.338 | |
| somatic diversification of immunoglobulins | GO:0016445 | 6 | 0.331 | |
| telomere maintenance via recombination | GO:0000722 | 4 | 0.329 | |
| telomere organization | GO:0032200 | 33 | 0.303 | Fly |
| mitotic g2 m transition checkpoint | GO:0044818 | 9 | 0.294 | Mouse Fly |
| mitotic dna integrity checkpoint | GO:0044774 | 30 | 0.294 | Mouse Fly |
| dna recombination | GO:0006310 | 77 | 0.290 | Yeast |
| mitotic recombination | GO:0006312 | 8 | 0.288 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.281 | |
| positive regulation of dna damage response signal transduction by p53 class mediator | GO:0043517 | 8 | 0.277 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.272 | |
| positive regulation of protein autophosphorylation | GO:0031954 | 9 | 0.272 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.268 | |
| anatomical structure homeostasis | GO:0060249 | 100 | 0.267 | Fly |
| rna dependent dna replication | GO:0006278 | 16 | 0.264 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.260 | |
| protein maturation | GO:0051604 | 233 | 0.255 | |
| mitotic dna damage checkpoint | GO:0044773 | 28 | 0.248 | Mouse Fly |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.245 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.243 | |
| mapk cascade | GO:0000165 | 288 | 0.239 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.237 | |
| nuclear division | GO:0000280 | 128 | 0.234 | Yeast Mouse Worm |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.228 | |
| negative regulation of glial cell apoptotic process | GO:0034351 | 6 | 0.227 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.224 | Mouse Fly |
| nucleosome assembly | GO:0006334 | 50 | 0.218 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.207 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.204 | Yeast |
| leukocyte activation involved in immune response | GO:0002366 | 30 | 0.197 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 158 | 0.191 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.189 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.186 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.182 | Mouse Fly |
| lymphocyte activation | GO:0046649 | 133 | 0.182 | |
| mitotic dna replication checkpoint | GO:0033314 | 2 | 0.179 | |
| oocyte differentiation | GO:0009994 | 2 | 0.178 | |
| growth | GO:0040007 | 202 | 0.177 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.177 | |
| signal transduction involved in dna damage checkpoint | GO:0072422 | 15 | 0.175 | |
| chordate embryonic development | GO:0043009 | 34 | 0.172 | |
| regulation of dna recombination | GO:0000018 | 23 | 0.167 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.165 | |
| immune response | GO:0006955 | 307 | 0.165 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.163 | |
| signal transduction involved in mitotic dna integrity checkpoint | GO:1902403 | 13 | 0.160 | |
| neuromuscular process | GO:0050905 | 15 | 0.156 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.156 | |
| leukocyte mediated immunity | GO:0002443 | 59 | 0.155 | |
| histone h3 k4 methylation | GO:0051568 | 27 | 0.154 | |
| histone h2a phosphorylation | GO:1990164 | 3 | 0.153 | |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.147 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.146 | |
| mitotic g2 dna damage checkpoint | GO:0007095 | 7 | 0.145 | Mouse Fly |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.143 | Worm |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.141 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.141 | |
| dna dependent dna replication maintenance of fidelity | GO:0045005 | 14 | 0.137 | |
| response to uv | GO:0009411 | 73 | 0.133 | |
| lipoprotein catabolic process | GO:0042159 | 1 | 0.132 | |
| viral life cycle | GO:0019058 | 132 | 0.132 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.130 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.123 | |
| regulation of dna repair | GO:0006282 | 47 | 0.122 | |
| protein homooligomerization | GO:0051260 | 100 | 0.120 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 38 | 0.119 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.118 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 50 | 0.112 | |
| lymphocyte mediated immunity | GO:0002449 | 48 | 0.108 | |
| regulation of lymphocyte activation | GO:0051249 | 103 | 0.107 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.106 | |
| segmentation | GO:0035282 | 4 | 0.102 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.102 | Mouse Fly |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 102 | 0.101 | Yeast |
| regulation of cell cycle process | GO:0010564 | 266 | 0.101 | |
| system process | GO:0003008 | 349 | 0.098 | |
| morphogenesis of an epithelium | GO:0002009 | 60 | 0.098 | |
| chromosome separation | GO:0051304 | 23 | 0.097 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.095 | |
| stress activated mapk cascade | GO:0051403 | 93 | 0.095 | |
| dna replication independent nucleosome organization | GO:0034724 | 27 | 0.094 | |
| spindle assembly checkpoint | GO:0071173 | 17 | 0.092 | |
| cellular response to ionizing radiation | GO:0071479 | 32 | 0.085 | |
| adaptive immune response | GO:0002250 | 49 | 0.084 | |
| somatic cell dna recombination | GO:0016444 | 6 | 0.084 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.083 | |
| mismatch repair | GO:0006298 | 15 | 0.081 | |
| neuron death | GO:0070997 | 65 | 0.081 | |
| glycerolipid metabolic process | GO:0046486 | 107 | 0.081 | |
| dna replication | GO:0006260 | 116 | 0.080 | |
| cell activation involved in immune response | GO:0002263 | 30 | 0.079 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.079 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.079 | Mouse Fly |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.077 | Mouse Fly |
| nucleotide catabolic process | GO:0009166 | 408 | 0.076 | |
| intra s dna damage checkpoint | GO:0031573 | 4 | 0.075 | Mouse |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.073 | |
| interstrand cross link repair | GO:0036297 | 3 | 0.073 | |
| phosphatidylinositol 3 phosphate biosynthetic process | GO:0036092 | 3 | 0.073 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.072 | |
| leukocyte differentiation | GO:0002521 | 98 | 0.070 | |
| leukocyte activation | GO:0045321 | 164 | 0.069 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.069 | |
| double strand break repair via nonhomologous end joining | GO:0006303 | 10 | 0.068 | Yeast |
| response to oxygen containing compound | GO:1901700 | 369 | 0.068 | |
| replicative senescence | GO:0090399 | 8 | 0.067 | |
| positive regulation of helicase activity | GO:0051096 | 6 | 0.066 | |
| regulation of double strand break repair via homologous recombination | GO:0010569 | 11 | 0.066 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.066 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.066 | |
| response to oxidative stress | GO:0006979 | 121 | 0.065 | |
| cell activation | GO:0001775 | 213 | 0.065 | |
| somatic diversification of immune receptors | GO:0002200 | 8 | 0.065 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.065 | |
| regulation of neuron apoptotic process | GO:0043523 | 35 | 0.064 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.064 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 158 | 0.064 | |
| regulation of chromosome segregation | GO:0051983 | 44 | 0.063 | |
| chromatin modification | GO:0016568 | 298 | 0.063 | |
| regulation of transcription by chromatin organization | GO:0034401 | 1 | 0.063 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.062 | |
| mitochondrion organization | GO:0007005 | 156 | 0.060 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.060 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.060 | |
| dna templated transcription initiation | GO:0006352 | 35 | 0.060 | |
| chromatin organization | GO:0006325 | 351 | 0.060 | |
| brain development | GO:0007420 | 97 | 0.060 | |
| dna replication independent nucleosome assembly | GO:0006336 | 27 | 0.059 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.059 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.059 | Mouse Worm Fly |
| immune system development | GO:0002520 | 195 | 0.058 | |
| positive regulation of chromosome organization | GO:2001252 | 41 | 0.057 | |
| negative regulation of histone h3 k9 methylation | GO:0051573 | 3 | 0.057 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.056 | |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.056 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.056 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.055 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.055 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.055 | |
| negative regulation of hematopoietic progenitor cell differentiation | GO:1901533 | 18 | 0.054 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.054 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.054 | |
| organelle localization | GO:0051640 | 84 | 0.053 | |
| female gamete generation | GO:0007292 | 2 | 0.052 | |
| histone h4 acetylation | GO:0043967 | 47 | 0.052 | |
| central nervous system development | GO:0007417 | 123 | 0.052 | |
| negative regulation of immune system process | GO:0002683 | 136 | 0.050 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.050 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.050 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.050 | |
| male gonad development | GO:0008584 | 23 | 0.050 | |
| dna packaging | GO:0006323 | 77 | 0.049 | |
| production of molecular mediator of immune response | GO:0002440 | 37 | 0.049 | |
| immune effector process | GO:0002252 | 159 | 0.048 | |
| embryo development | GO:0009790 | 123 | 0.048 | Worm |
| neuron apoptotic process | GO:0051402 | 39 | 0.048 | |
| meiosis i | GO:0007127 | 4 | 0.047 | Yeast Mouse |
| regulation of protein processing | GO:0070613 | 150 | 0.047 | |
| histone methylation | GO:0016571 | 60 | 0.047 | |
| mitotic spindle assembly checkpoint | GO:0007094 | 14 | 0.047 | |
| histone modification | GO:0016570 | 251 | 0.045 | |
| oocyte development | GO:0048599 | 1 | 0.045 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.045 | |
| negative regulation of sister chromatid segregation | GO:0033046 | 17 | 0.045 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.045 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.044 | |
| mitotic spindle checkpoint | GO:0071174 | 18 | 0.044 | |
| spindle checkpoint | GO:0031577 | 26 | 0.044 | |
| positive regulation of signal transduction by p53 class mediator | GO:1901798 | 10 | 0.044 | |
| circulatory system development | GO:0072359 | 262 | 0.044 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.043 | |
| immunoglobulin production involved in immunoglobulin mediated immune response | GO:0002381 | 5 | 0.041 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.041 | |
| microtubule based process | GO:0007017 | 210 | 0.040 | |
| somitogenesis | GO:0001756 | 2 | 0.039 | |
| regulation of mononuclear cell proliferation | GO:0032944 | 65 | 0.038 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.038 | |
| compound eye development | GO:0048749 | 1 | 0.038 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.037 | |
| positive regulation of immunoglobulin mediated immune response | GO:0002891 | 4 | 0.037 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.037 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.037 | |
| response to purine containing compound | GO:0014074 | 40 | 0.037 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.036 | |
| cell aging | GO:0007569 | 52 | 0.036 | |
| rho protein signal transduction | GO:0007266 | 26 | 0.036 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.035 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.035 | |
| head development | GO:0060322 | 108 | 0.035 | |
| negative regulation of dna metabolic process | GO:0051053 | 57 | 0.035 | |
| negative regulation of chromosome organization | GO:2001251 | 48 | 0.035 | |
| positive regulation of histone methylation | GO:0031062 | 12 | 0.035 | |
| negative regulation of mitotic sister chromatid segregation | GO:0033048 | 17 | 0.035 | |
| positive regulation of histone h3 k4 methylation | GO:0051571 | 8 | 0.035 | |
| regulation of growth | GO:0040008 | 165 | 0.035 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.034 | |
| regulation of protein localization | GO:0032880 | 296 | 0.034 | |
| cell morphogenesis | GO:0000902 | 296 | 0.033 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.033 | |
| cell projection organization | GO:0030030 | 252 | 0.033 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.033 | |
| negative regulation of dna replication | GO:0008156 | 29 | 0.033 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.032 | |
| negative regulation of meiotic cell cycle | GO:0051447 | 2 | 0.032 | |
| epithelium development | GO:0060429 | 227 | 0.032 | |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.032 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.032 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.031 | |
| positive regulation of chromatin assembly or disassembly | GO:0045799 | 2 | 0.031 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.031 | |
| cilium assembly | GO:0042384 | 63 | 0.031 | |
| regulation of developmental growth | GO:0048638 | 30 | 0.031 | |
| negative regulation of metaphase anaphase transition of cell cycle | GO:1902100 | 17 | 0.030 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.030 | |
| macromolecule methylation | GO:0043414 | 97 | 0.030 | |
| stem cell development | GO:0048864 | 69 | 0.029 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.029 | |
| gliogenesis | GO:0042063 | 21 | 0.029 | |
| methylation | GO:0032259 | 106 | 0.029 | |
| regulation of viral process | GO:0050792 | 103 | 0.029 | |
| lipid biosynthetic process | GO:0008610 | 177 | 0.029 | |
| b cell activation | GO:0042113 | 33 | 0.029 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.028 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.028 | |
| peptidyl serine modification | GO:0018209 | 106 | 0.028 | |
| lymphocyte activation involved in immune response | GO:0002285 | 20 | 0.028 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.027 | |
| protein alkylation | GO:0008213 | 74 | 0.027 | |
| regulation of telomere maintenance | GO:0032204 | 13 | 0.027 | |
| multi organism reproductive process | GO:0044703 | 54 | 0.026 | Yeast |
| glycerolipid biosynthetic process | GO:0045017 | 51 | 0.026 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.026 | |
| single organism cellular localization | GO:1902580 | 332 | 0.026 | |
| dna dependent dna replication | GO:0006261 | 44 | 0.026 | |
| vasculature development | GO:0001944 | 181 | 0.026 | |
| rna splicing | GO:0008380 | 131 | 0.026 | |
| cell cycle g2 m phase transition | GO:0044839 | 43 | 0.026 | |
| regulation of stress activated mapk cascade | GO:0032872 | 84 | 0.025 | |
| protein localization to organelle | GO:0033365 | 280 | 0.025 | |
| lymphocyte differentiation | GO:0030098 | 35 | 0.025 | |
| regulation of signal transduction by p53 class mediator | GO:1901796 | 26 | 0.025 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.025 | |
| protein processing | GO:0016485 | 226 | 0.024 | |
| response to oxygen levels | GO:0070482 | 100 | 0.024 | |
| detection of muramyl dipeptide | GO:0032498 | 1 | 0.024 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.024 | |
| negative regulation of mitotic metaphase anaphase transition | GO:0045841 | 17 | 0.024 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.024 | |
| positive regulation of homeostatic process | GO:0032846 | 47 | 0.024 | |
| neuron remodeling | GO:0016322 | 2 | 0.024 | |
| regeneration | GO:0031099 | 4 | 0.023 | |
| mitotic nuclear division | GO:0007067 | 119 | 0.023 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 37 | 0.023 | |
| regulation of dna replication | GO:0006275 | 68 | 0.023 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.023 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.023 | Mouse Fly |
| atp catabolic process | GO:0006200 | 157 | 0.023 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.022 | |
| intracellular protein transport | GO:0006886 | 270 | 0.022 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.022 | Mouse Fly |
| secretion | GO:0046903 | 254 | 0.022 | |
| rna processing | GO:0006396 | 255 | 0.022 | |
| pattern specification process | GO:0007389 | 43 | 0.022 | |
| carboxylic acid biosynthetic process | GO:0046394 | 97 | 0.022 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.022 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.022 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 35 | 0.021 | |
| response to nutrient levels | GO:0031667 | 81 | 0.021 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.021 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.021 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.021 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.021 | |
| negative regulation of proteasomal protein catabolic process | GO:1901799 | 32 | 0.021 | |
| response to inorganic substance | GO:0010035 | 127 | 0.021 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 56 | 0.020 | |
| negative regulation of defense response | GO:0031348 | 47 | 0.020 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.020 | |
| actin filament based process | GO:0030029 | 224 | 0.020 | |
| amine metabolic process | GO:0009308 | 44 | 0.020 | |
| anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process | GO:0031145 | 25 | 0.020 | |
| oxidation reduction process | GO:0055114 | 396 | 0.020 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.020 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 48 | 0.020 | |
| multicellular organismal signaling | GO:0035637 | 34 | 0.020 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.020 | |
| positive regulation of transcription initiation from rna polymerase ii promoter | GO:0060261 | 4 | 0.019 | |
| stem cell differentiation | GO:0048863 | 93 | 0.019 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.019 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.019 | |
| anterior posterior axis specification embryo | GO:0008595 | 2 | 0.019 | |
| response to hormone | GO:0009725 | 175 | 0.019 | |
| signal transduction by p53 class mediator | GO:0072331 | 72 | 0.019 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.019 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.018 | |
| detection of stimulus | GO:0051606 | 85 | 0.018 | |
| intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator | GO:0042771 | 23 | 0.018 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.018 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.018 | |
| cell development | GO:0048468 | 328 | 0.018 | Yeast |
| regulation of stress activated protein kinase signaling cascade | GO:0070302 | 85 | 0.018 | |
| lipid metabolic process | GO:0006629 | 381 | 0.018 | |
| negative regulation of cell division | GO:0051782 | 31 | 0.017 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.017 | |
| negative regulation of protein catabolic process | GO:0042177 | 59 | 0.017 | |
| mrna metabolic process | GO:0016071 | 175 | 0.017 | |
| histone mrna catabolic process | GO:0071044 | 10 | 0.017 | |
| negative regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032435 | 30 | 0.017 | |
| epithelial cell differentiation | GO:0030855 | 141 | 0.017 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.017 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.017 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 71 | 0.017 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.017 | |
| positive regulation of dna metabolic process | GO:0051054 | 73 | 0.017 | |
| regulation of protein targeting | GO:1903533 | 91 | 0.017 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.017 | |
| response to light stimulus | GO:0009416 | 87 | 0.017 | |
| protein dephosphorylation | GO:0006470 | 81 | 0.017 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.017 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.016 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.016 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.016 | |
| organelle assembly | GO:0070925 | 176 | 0.016 | |
| response to hypoxia | GO:0001666 | 96 | 0.016 | |
| gtp catabolic process | GO:0006184 | 237 | 0.016 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.016 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.016 | |
| phosphatidylinositol metabolic process | GO:0046488 | 53 | 0.016 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.015 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.015 | |
| reproductive process | GO:0022414 | 106 | 0.015 | Yeast |
| regulation of dna methylation | GO:0044030 | 2 | 0.015 | |
| protein methylation | GO:0006479 | 74 | 0.015 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.015 | |
| regulation of intracellular protein transport | GO:0033157 | 123 | 0.015 | |
| nervous system development | GO:0007399 | 293 | 0.015 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.015 | |
| protein acylation | GO:0043543 | 138 | 0.015 | |
| regulation of cell division | GO:0051302 | 116 | 0.015 | |
| protein ubiquitination | GO:0016567 | 314 | 0.015 | |
| cellular response to reactive oxygen species | GO:0034614 | 50 | 0.015 | |
| regulation of mitotic sister chromatid separation | GO:0010965 | 27 | 0.015 | |
| regulation of dna biosynthetic process | GO:2000278 | 18 | 0.014 | |
| action potential | GO:0001508 | 34 | 0.014 | |
| retina homeostasis | GO:0001895 | 42 | 0.014 | |
| cilium morphogenesis | GO:0060271 | 75 | 0.014 | |
| protein deubiquitination | GO:0016579 | 79 | 0.014 | |
| positive regulation of viral process | GO:0048524 | 37 | 0.014 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.014 | Yeast |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.014 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.014 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.014 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.013 | |
| regulation of membrane potential | GO:0042391 | 95 | 0.013 | |
| oocyte maturation | GO:0001556 | 1 | 0.013 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.013 | |
| histone h4 k20 methylation | GO:0034770 | 1 | 0.013 | |
| reproduction | GO:0000003 | 63 | 0.013 | Yeast Mouse Worm |
| cellular protein catabolic process | GO:0044257 | 261 | 0.013 | |
| positive regulation of response to dna damage stimulus | GO:2001022 | 43 | 0.013 | |
| oogenesis | GO:0048477 | 2 | 0.013 | |
| mitotic g1 dna damage checkpoint | GO:0031571 | 17 | 0.013 | |
| negative regulation of g2 m transition of mitotic cell cycle | GO:0010972 | 9 | 0.013 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.013 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.013 | |
| intracellular mrna localization | GO:0008298 | 1 | 0.013 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.013 | |
| positive regulation of dna replication | GO:0045740 | 35 | 0.013 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.013 | |
| regulation of dna templated transcription elongation | GO:0032784 | 23 | 0.013 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.013 | |
| response to alkaloid | GO:0043279 | 20 | 0.013 | |
| adipose tissue development | GO:0060612 | 2 | 0.013 | |
| monocarboxylic acid metabolic process | GO:0032787 | 185 | 0.013 | |
| regulation of rho protein signal transduction | GO:0035023 | 79 | 0.013 | |
| negative regulation of response to wounding | GO:1903035 | 47 | 0.012 | |
| response to caffeine | GO:0031000 | 3 | 0.012 | |
| positive regulation of cell activation | GO:0050867 | 81 | 0.012 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.012 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.012 | |
| positive regulation of leukocyte activation | GO:0002696 | 80 | 0.012 | |
| b cell mediated immunity | GO:0019724 | 10 | 0.012 | |
| lymphocyte proliferation | GO:0046651 | 70 | 0.012 | |
| gene silencing | GO:0016458 | 49 | 0.012 | |
| meiotic cell cycle | GO:0051321 | 13 | 0.012 | Yeast Mouse Worm |
| nuclear transport | GO:0051169 | 179 | 0.012 | |
| internal protein amino acid acetylation | GO:0006475 | 101 | 0.012 | |
| regulation of immune response | GO:0050776 | 201 | 0.012 | |
| positive regulation of microtubule polymerization or depolymerization | GO:0031112 | 8 | 0.012 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.012 | |
| epithelial cell development | GO:0002064 | 34 | 0.012 | |
| maintenance of dna repeat elements | GO:0043570 | 4 | 0.012 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.012 | |
| cytokine production | GO:0001816 | 247 | 0.012 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.012 | |
| signal transduction involved in mitotic dna damage checkpoint | GO:1902402 | 13 | 0.012 | |
| lipoprotein metabolic process | GO:0042157 | 42 | 0.012 | |
| signal transduction involved in mitotic g1 dna damage checkpoint | GO:0072431 | 10 | 0.012 | |
| gtp metabolic process | GO:0046039 | 239 | 0.012 | |
| histone phosphorylation | GO:0016572 | 16 | 0.011 | |
| regulation of protein transport | GO:0051223 | 213 | 0.011 | |
| histone lysine methylation | GO:0034968 | 50 | 0.011 | |
| cell projection assembly | GO:0030031 | 126 | 0.011 | |
| cellular response to nutrient levels | GO:0031669 | 69 | 0.011 | |