IMP: Integrative Multi-species Prediction

Homo sapiens

4 known processes

NDUFA6

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa

(Aliases: CI-B14,B14,LYRM6,NADHB14)

Entrez: 4700
MIM: 602138
HPRD: 11884
Ensembl: ENSG00000184983
HGNC: 7690
UniProtKB: P56556

Process Predictions
Disease Predictions

NDUFA6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
post embryonic development	GO:0009791	2	0.704	Worm
determination of adult lifespan	GO:0008340	2	0.684	Worm
multicellular organismal aging	GO:0010259	3	0.507	Worm
ribonucleoside monophosphate catabolic process	GO:0009158	158	0.179
nucleoside triphosphate metabolic process	GO:0009141	422	0.160
transmembrane transport	GO:0055085	399	0.137
cation transport	GO:0006812	331	0.131
embryo development	GO:0009790	123	0.114	Worm
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.113
spermatid development	GO:0007286	4	0.113
purine ribonucleoside metabolic process	GO:0046128	437	0.106
inorganic cation transmembrane transport	GO:0098662	194	0.103
cation transmembrane transport	GO:0098655	238	0.092
atp catabolic process	GO:0006200	157	0.092
mating	GO:0007618	1	0.083
nucleoside monophosphate metabolic process	GO:0009123	191	0.082
purine nucleoside catabolic process	GO:0006152	398	0.073
ribonucleoside catabolic process	GO:0042454	406	0.070
aging	GO:0007568	66	0.064	Worm
organonitrogen compound biosynthetic process	GO:1901566	200	0.058
nucleoside catabolic process	GO:0009164	408	0.054
spermatid differentiation	GO:0048515	4	0.054
nucleoside monophosphate catabolic process	GO:0009125	159	0.054
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.047
ion transmembrane transport	GO:0034220	338	0.045
organelle assembly	GO:0070925	176	0.045
growth	GO:0040007	202	0.044
intracellular protein transport	GO:0006886	270	0.040
embryo development ending in birth or egg hatching	GO:0009792	34	0.038	Worm
nucleoside phosphate catabolic process	GO:1901292	412	0.035
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.034
purine ribonucleotide catabolic process	GO:0009154	404	0.033
nucleotide catabolic process	GO:0009166	408	0.031
carbohydrate derivative biosynthetic process	GO:1901137	207	0.030
protein localization to organelle	GO:0033365	280	0.030
cellular component morphogenesis	GO:0032989	314	0.029
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.026
monocarboxylic acid metabolic process	GO:0032787	185	0.025
hindbrain development	GO:0030902	3	0.023
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.022
nucleoside triphosphate catabolic process	GO:0009143	394	0.022
glycosyl compound catabolic process	GO:1901658	413	0.022
regulation of growth	GO:0040008	165	0.022
single organism membrane organization	GO:0044802	268	0.021
midbrain development	GO:0030901	45	0.021
purine containing compound catabolic process	GO:0072523	411	0.020
neural nucleus development	GO:0048857	47	0.020
cytoplasmic transport	GO:0016482	379	0.019
central nervous system development	GO:0007417	123	0.019
protein transmembrane transport	GO:0071806	25	0.018
positive regulation of programmed cell death	GO:0043068	249	0.018
organophosphate biosynthetic process	GO:0090407	163	0.018
generation of precursor metabolites and energy	GO:0006091	68	0.018
mitochondrial transport	GO:0006839	60	0.018
substantia nigra development	GO:0021762	45	0.018
protein maturation	GO:0051604	233	0.018
organophosphate catabolic process	GO:0046434	430	0.018
maintenance of location	GO:0051235	112	0.017
response to abiotic stimulus	GO:0009628	336	0.017
membrane organization	GO:0061024	292	0.016
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.016
inner mitochondrial membrane organization	GO:0007007	8	0.015
cell differentiation in spinal cord	GO:0021515	1	0.015
cell growth	GO:0016049	160	0.015
monovalent inorganic cation transport	GO:0015672	128	0.015
regulation of protein catabolic process	GO:0042176	155	0.014
cell development	GO:0048468	328	0.014
reproductive process	GO:0022414	106	0.014
cellular response to endogenous stimulus	GO:0071495	336	0.014
purine ribonucleoside catabolic process	GO:0046130	398	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.013
anatomical structure formation involved in morphogenesis	GO:0048646	284	0.013
female gamete generation	GO:0007292	2	0.013
reproduction	GO:0000003	63	0.013
atp metabolic process	GO:0046034	176	0.012
regulation of peptidase activity	GO:0052547	180	0.012
purine nucleoside monophosphate metabolic process	GO:0009126	186	0.012
muscle system process	GO:0003012	81	0.011
negative regulation of intracellular signal transduction	GO:1902532	183	0.011
positive regulation of developmental process	GO:0051094	314	0.011
response to oxygen levels	GO:0070482	100	0.011
head development	GO:0060322	108	0.011
protein targeting	GO:0006605	187	0.011
nervous system development	GO:0007399	293	0.011
purine nucleoside monophosphate catabolic process	GO:0009128	158	0.011
endomembrane system organization	GO:0010256	196	0.011
regulation of apoptotic signaling pathway	GO:2001233	175	0.011
regulation of proteolysis	GO:0030162	293	0.011
proton transport	GO:0015992	22	0.011
deoxyribose phosphate metabolic process	GO:0019692	6	0.011
divalent metal ion transport	GO:0070838	152	0.011
tissue regeneration	GO:0042246	3	0.010
inorganic ion transmembrane transport	GO:0098660	231	0.010
negative regulation of programmed cell death	GO:0043069	321	0.010
hydrogen transport	GO:0006818	23	0.010
positive regulation of hydrolase activity	GO:0051345	331	0.010
multicellular organism growth	GO:0035264	8	0.010
single organism cellular localization	GO:1902580	332	0.010
endocytosis	GO:0006897	159	0.010
neuromuscular junction development	GO:0007528	3	0.010

NDUFA6 disease predictions

Disease	DO term ID	Size	Probability
disease of metabolism	DOID:0014667	295	0.019
inherited metabolic disorder	DOID:655	242	0.019
leigh disease	DOID:3652	16	0.017
mitochondrial metabolism disease	DOID:700	29	0.017
sensory system disease	DOID:0050155	203	0.015
nervous system disease	DOID:863	431	0.015
organ system cancer	DOID:0050686	164	0.014
cancer	DOID:162	167	0.014
disease of cellular proliferation	DOID:14566	174	0.014

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