IMP: Integrative Multi-species Prediction

Homo sapiens

0 known processes

NDUFS6

NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)

(Aliases: CI13KDA,CI-13kD-A,CI-13kA)

Entrez: 4726
HPRD: 10356
Ensembl: ENSG00000145494
MIM: 603848
HGNC: 7713
UniProtKB: O75380
UniProtKB: Q6IBC4

Process Predictions
Disease Predictions

NDUFS6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
post embryonic development	GO:0009791	2	0.959	Worm
vesicle mediated transport	GO:0016192	371	0.453
multicellular organismal aging	GO:0010259	3	0.307	Mouse
purine ribonucleoside metabolic process	GO:0046128	437	0.236	Worm
purine nucleoside catabolic process	GO:0006152	398	0.233
endocytosis	GO:0006897	159	0.211
spinal cord development	GO:0021510	4	0.196
determination of adult lifespan	GO:0008340	2	0.188
oogenesis	GO:0048477	2	0.144
purine ribonucleoside monophosphate catabolic process	GO:0009169	158	0.133
embryo development	GO:0009790	123	0.123	Worm
receptor mediated endocytosis	GO:0006898	84	0.121
embryo development ending in birth or egg hatching	GO:0009792	34	0.105	Worm
inner mitochondrial membrane organization	GO:0007007	8	0.102
cell development	GO:0048468	328	0.102
mitochondrial transport	GO:0006839	60	0.098
female gamete generation	GO:0007292	2	0.084
mitochondrion organization	GO:0007005	156	0.084	Mouse
nucleoside triphosphate metabolic process	GO:0009141	422	0.081	Worm
reproduction	GO:0000003	63	0.079
organophosphate catabolic process	GO:0046434	430	0.076
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.072	Worm
membrane organization	GO:0061024	292	0.070
nervous system development	GO:0007399	293	0.065
nucleoside monophosphate metabolic process	GO:0009123	191	0.063	Worm
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.054	Worm
atp catabolic process	GO:0006200	157	0.049
purine ribonucleotide catabolic process	GO:0009154	404	0.046
actin filament based process	GO:0030029	224	0.045
aging	GO:0007568	66	0.043	Mouse
positive regulation of hydrolase activity	GO:0051345	331	0.039
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.038
nucleoside phosphate catabolic process	GO:1901292	412	0.038
organonitrogen compound biosynthetic process	GO:1901566	200	0.037
negative regulation of apoptotic signaling pathway	GO:2001234	97	0.036
regulation of apoptotic signaling pathway	GO:2001233	175	0.035
mitochondrial respiratory chain complex i biogenesis	GO:0097031	16	0.035
ribonucleotide catabolic process	GO:0009261	405	0.035
ribonucleoside catabolic process	GO:0042454	406	0.035
positive regulation of programmed cell death	GO:0043068	249	0.032
reproductive process	GO:0022414	106	0.032
reactive oxygen species metabolic process	GO:0072593	75	0.032
anatomical structure formation involved in morphogenesis	GO:0048646	284	0.031
positive regulation of apoptotic process	GO:0043065	246	0.030
atp metabolic process	GO:0046034	176	0.030	Worm
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.030	Worm
protein localization to organelle	GO:0033365	280	0.027
organelle assembly	GO:0070925	176	0.025
negative regulation of intracellular signal transduction	GO:1902532	183	0.025
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.025
protein catabolic process	GO:0030163	325	0.025
intracellular protein transport	GO:0006886	270	0.025
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.025	Worm
intrinsic apoptotic signaling pathway	GO:0097193	127	0.024
single organism membrane organization	GO:0044802	268	0.024
regulation of growth	GO:0040008	165	0.024
purine nucleotide catabolic process	GO:0006195	405	0.024
negative regulation of multicellular organismal process	GO:0051241	317	0.024
lipid localization	GO:0010876	106	0.022
glycosyl compound catabolic process	GO:1901658	413	0.022
single organism cellular localization	GO:1902580	332	0.021
regulation of proteolysis	GO:0030162	293	0.021
response to drug	GO:0042493	81	0.021	Worm
purine nucleoside monophosphate catabolic process	GO:0009128	158	0.021
cell cell signaling	GO:0007267	155	0.021
nucleoside triphosphate catabolic process	GO:0009143	394	0.021
developmental process involved in reproduction	GO:0003006	66	0.021
regulation of endopeptidase activity	GO:0052548	170	0.020
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.020
positive regulation of catabolic process	GO:0009896	310	0.020
response to lipid	GO:0033993	206	0.020
positive regulation of purine nucleotide catabolic process	GO:0033123	185	0.020
neuromuscular junction development	GO:0007528	3	0.020
neurological system process	GO:0050877	163	0.020
oocyte development	GO:0048599	1	0.019
response to oxidative stress	GO:0006979	121	0.019
atp synthesis coupled electron transport	GO:0042773	4	0.019	Worm
single organism reproductive process	GO:0044702	98	0.019
central nervous system development	GO:0007417	123	0.019
generation of neurons	GO:0048699	152	0.019
regulation of membrane potential	GO:0042391	95	0.018
cellular macromolecule catabolic process	GO:0044265	380	0.018
spermatid development	GO:0007286	4	0.018
response to oxygen containing compound	GO:1901700	369	0.018
positive regulation of nucleotide metabolic process	GO:0045981	230	0.018
ribonucleoside monophosphate catabolic process	GO:0009158	158	0.018
nucleoside catabolic process	GO:0009164	408	0.017
neurogenesis	GO:0022008	169	0.017
negative regulation of growth	GO:0045926	97	0.017
cell growth	GO:0016049	160	0.016
cellular protein complex assembly	GO:0043623	188	0.016
multicellular organism reproduction	GO:0032504	42	0.016
positive regulation of proteolysis	GO:0045862	142	0.016
regulation of cell development	GO:0060284	161	0.016
regulation of response to external stimulus	GO:0032101	222	0.015
head development	GO:0060322	108	0.015
spermatid differentiation	GO:0048515	4	0.015
nucleoside monophosphate catabolic process	GO:0009125	159	0.015
positive regulation of cell death	GO:0010942	263	0.015
development of primary sexual characteristics	GO:0045137	35	0.015
cellular component morphogenesis	GO:0032989	314	0.014	Mouse
positive regulation of nucleoside metabolic process	GO:0045979	186	0.014
regulation of cell cycle	GO:0051726	393	0.014
mitotic nuclear division	GO:0007067	119	0.014
ribonucleotide biosynthetic process	GO:0009260	81	0.014
purine ribonucleoside catabolic process	GO:0046130	398	0.014
cellular amine metabolic process	GO:0044106	41	0.013
regulation of cell cycle phase transition	GO:1901987	126	0.013
mitochondrial membrane organization	GO:0007006	40	0.013
autophagy	GO:0006914	88	0.013
cell division	GO:0051301	168	0.013
brain development	GO:0007420	97	0.013
phospholipid metabolic process	GO:0006644	99	0.013
mitotic cell cycle process	GO:1903047	286	0.013
multi organism reproductive process	GO:0044703	54	0.013
positive regulation of purine nucleotide metabolic process	GO:1900544	227	0.012
purine ribonucleotide biosynthetic process	GO:0009152	79	0.012
sulfur compound metabolic process	GO:0006790	101	0.012
regulation of nervous system development	GO:0051960	88	0.011
growth	GO:0040007	202	0.011	Mouse
protein import	GO:0017038	130	0.011
regulation of mitotic cell cycle	GO:0007346	189	0.011
regulation of cellular component biogenesis	GO:0044087	281	0.011
reproductive system development	GO:0061458	56	0.011	Mouse
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.010	Worm
oocyte differentiation	GO:0009994	2	0.010
establishment of protein localization to organelle	GO:0072594	172	0.010
nucleotide catabolic process	GO:0009166	408	0.010
carbohydrate derivative biosynthetic process	GO:1901137	207	0.010
response to cytokine	GO:0034097	232	0.010
reproductive structure development	GO:0048608	55	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.010

NDUFS6 disease predictions

Disease	DO term ID	Size	Probability
inherited metabolic disorder	DOID:655	242	0.362
disease of metabolism	DOID:0014667	295	0.362
mitochondrial metabolism disease	DOID:700	29	0.220
leigh disease	DOID:3652	16	0.220
disease of cellular proliferation	DOID:14566	174	0.040
cancer	DOID:162	167	0.032
organ system cancer	DOID:0050686	164	0.032
endocrine gland cancer	DOID:170	26	0.021
porphyria	DOID:13268	8	0.016

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