| positive regulation of immune system process | GO:0002684 | 283 | 0.386 | |
| immune response activating signal transduction | GO:0002757 | 90 | 0.363 | |
| response to lipopolysaccharide | GO:0032496 | 70 | 0.338 | Human |
| defense response to other organism | GO:0098542 | 129 | 0.335 | |
| cellular response to lipopolysaccharide | GO:0071222 | 57 | 0.320 | Human |
| cytokine production | GO:0001816 | 247 | 0.295 | |
| defense response | GO:0006952 | 315 | 0.283 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.240 | |
| regulation of defense response | GO:0031347 | 154 | 0.235 | |
| leukocyte activation | GO:0045321 | 164 | 0.228 | |
| innate immune response | GO:0045087 | 178 | 0.206 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.205 | Rat |
| cell activation | GO:0001775 | 213 | 0.193 | |
| activation of immune response | GO:0002253 | 114 | 0.183 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.181 | |
| regulation of cytokine production | GO:0001817 | 232 | 0.177 | |
| immune effector process | GO:0002252 | 159 | 0.171 | Human Rat |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.166 | |
| immune response regulating signaling pathway | GO:0002764 | 97 | 0.162 | |
| defense response to virus | GO:0051607 | 71 | 0.160 | Human |
| regulation of immune response | GO:0050776 | 201 | 0.152 | |
| positive regulation of leukocyte activation | GO:0002696 | 80 | 0.150 | |
| cellular response to biotic stimulus | GO:0071216 | 71 | 0.148 | Human |
| cellular response to muramyl dipeptide | GO:0071225 | 3 | 0.148 | |
| regulation of innate immune response | GO:0045088 | 97 | 0.145 | |
| hemopoiesis | GO:0030097 | 180 | 0.140 | |
| interleukin 12 secretion | GO:0072610 | 1 | 0.139 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.138 | |
| interferon gamma production | GO:0032609 | 39 | 0.138 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.135 | Human |
| response to other organism | GO:0051707 | 261 | 0.134 | |
| regulation of dendritic cell apoptotic process | GO:2000668 | 4 | 0.131 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.130 | Human |
| innate immune response activating signal transduction | GO:0002758 | 48 | 0.129 | |
| negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell | GO:2001189 | 1 | 0.127 | |
| positive regulation of lymphocyte activation | GO:0051251 | 73 | 0.126 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 48 | 0.118 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.116 | |
| response to lipid | GO:0033993 | 206 | 0.116 | Human |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.115 | |
| positive regulation of t helper 1 type immune response | GO:0002827 | 4 | 0.114 | |
| immune response | GO:0006955 | 307 | 0.114 | |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 45 | 0.111 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.110 | |
| cd8 positive alpha beta t cell activation | GO:0036037 | 3 | 0.110 | |
| cellular response to lipid | GO:0071396 | 127 | 0.109 | Human |
| nitrogen compound transport | GO:0071705 | 191 | 0.109 | Human |
| negative regulation of tumor necrosis factor biosynthetic process | GO:0042536 | 3 | 0.106 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.103 | |
| negative regulation of cd8 positive alpha beta t cell activation | GO:2001186 | 1 | 0.102 | |
| type i interferon secretion | GO:0072641 | 1 | 0.102 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 51 | 0.102 | |
| response to bacterium | GO:0009617 | 144 | 0.099 | |
| biological adhesion | GO:0022610 | 331 | 0.097 | |
| immune system development | GO:0002520 | 195 | 0.096 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.095 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.095 | Human |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.094 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 75 | 0.094 | |
| positive regulation of cell activation | GO:0050867 | 81 | 0.093 | |
| activation of innate immune response | GO:0002218 | 55 | 0.093 | |
| nucleotide binding oligomerization domain containing signaling pathway | GO:0070423 | 4 | 0.093 | |
| lymphocyte activation | GO:0046649 | 133 | 0.090 | |
| protein maturation | GO:0051604 | 233 | 0.090 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 99 | 0.090 | |
| positive regulation of immune response | GO:0050778 | 159 | 0.088 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 0.087 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.085 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.084 | Human |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 132 | 0.084 | |
| secretion | GO:0046903 | 254 | 0.084 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 62 | 0.083 | Human |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.082 | |
| detection of stimulus | GO:0051606 | 85 | 0.080 | |
| negative regulation of alpha beta t cell activation | GO:0046636 | 3 | 0.079 | |
| transmembrane transport | GO:0055085 | 399 | 0.078 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.078 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.078 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.077 | |
| regulation of immune effector process | GO:0002697 | 91 | 0.076 | Rat |
| regulation of kinase activity | GO:0043549 | 314 | 0.076 | Human |
| multicellular organismal aging | GO:0010259 | 3 | 0.076 | |
| cd4 positive alpha beta t cell differentiation involved in immune response | GO:0002294 | 4 | 0.076 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.075 | Human |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.074 | |
| positive regulation of immune effector process | GO:0002699 | 40 | 0.074 | Rat |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.072 | |
| positive regulation of innate immune response | GO:0045089 | 79 | 0.072 | |
| serotonin transport | GO:0006837 | 3 | 0.071 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.070 | |
| regulation of gamma delta t cell activation involved in immune response | GO:2001191 | 1 | 0.069 | |
| positive regulation of interleukin 6 production | GO:0032755 | 21 | 0.068 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.067 | |
| response to virus | GO:0009615 | 126 | 0.066 | Human |
| response to organic cyclic compound | GO:0014070 | 204 | 0.064 | Rat |
| response to oxygen containing compound | GO:1901700 | 369 | 0.064 | |
| response to peptidoglycan | GO:0032494 | 3 | 0.064 | |
| response to molecule of bacterial origin | GO:0002237 | 82 | 0.064 | |
| interleukin 6 production | GO:0032635 | 37 | 0.063 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.062 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.062 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 45 | 0.061 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.060 | Human |
| t cell activation | GO:0042110 | 99 | 0.060 | Human |
| negative regulation of cell death | GO:0060548 | 345 | 0.060 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.060 | Human |
| regulation of interferon beta secretion | GO:0035547 | 1 | 0.059 | |
| amine metabolic process | GO:0009308 | 44 | 0.058 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.057 | Human |
| response to lipoteichoic acid | GO:0070391 | 3 | 0.057 | |
| negative regulation of serotonin secretion | GO:0014063 | 1 | 0.057 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.057 | |
| regulation of response to biotic stimulus | GO:0002831 | 55 | 0.057 | |
| regulation of defense response to virus | GO:0050688 | 33 | 0.057 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 40 | 0.056 | |
| regulation of calcium ion transport | GO:0051924 | 79 | 0.056 | |
| regulation of protein transport | GO:0051223 | 213 | 0.056 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.055 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.055 | Human |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.054 | |
| protein ubiquitination | GO:0016567 | 314 | 0.054 | |
| regulation of ion transport | GO:0043269 | 189 | 0.054 | |
| response to cytokine | GO:0034097 | 232 | 0.054 | Human |
| protein secretion | GO:0009306 | 98 | 0.054 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.053 | Human |
| protein processing | GO:0016485 | 226 | 0.053 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.053 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.053 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.053 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.052 | Human |
| regulation of t helper 1 type immune response | GO:0002825 | 5 | 0.052 | |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.051 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 81 | 0.051 | |
| post embryonic development | GO:0009791 | 2 | 0.051 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.051 | Human |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.051 | |
| regulation of protein localization | GO:0032880 | 296 | 0.050 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.050 | Human |
| positive regulation of t helper cell differentiation | GO:0045624 | 2 | 0.049 | |
| metal ion transport | GO:0030001 | 272 | 0.049 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.049 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.048 | |
| positive regulation of t cell activation | GO:0050870 | 54 | 0.048 | |
| negative regulation of interferon beta production | GO:0032688 | 4 | 0.048 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.048 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.048 | |
| positive regulation of lymphocyte differentiation | GO:0045621 | 13 | 0.047 | |
| regulation of circadian sleep wake cycle | GO:0042749 | 2 | 0.047 | |
| positive regulation of lymphocyte proliferation | GO:0050671 | 46 | 0.047 | |
| defense response to bacterium | GO:0042742 | 63 | 0.047 | |
| defense response to gram positive bacterium | GO:0050830 | 29 | 0.046 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.046 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.046 | |
| protein oligomerization | GO:0051259 | 173 | 0.046 | |
| calcium ion transport | GO:0006816 | 147 | 0.046 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.046 | |
| negative regulation of secretion | GO:0051048 | 58 | 0.046 | Human |
| regulation of interferon beta production | GO:0032648 | 22 | 0.045 | |
| regulation of mononuclear cell proliferation | GO:0032944 | 65 | 0.045 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.044 | |
| secretion by cell | GO:0032940 | 226 | 0.044 | |
| positive regulation of tumor necrosis factor superfamily cytokine production | GO:1903557 | 22 | 0.044 | |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.044 | |
| positive regulation of leukocyte proliferation | GO:0070665 | 48 | 0.044 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.044 | Human |
| regulation of adaptive immune response | GO:0002819 | 33 | 0.043 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.043 | |
| dendritic cell apoptotic process | GO:0097048 | 4 | 0.043 | |
| leukocyte differentiation | GO:0002521 | 98 | 0.042 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.042 | |
| myeloid leukocyte differentiation | GO:0002573 | 60 | 0.042 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.042 | |
| cd4 positive alpha beta t cell differentiation | GO:0043367 | 4 | 0.041 | |
| protein catabolic process | GO:0030163 | 325 | 0.041 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.041 | |
| cell adhesion | GO:0007155 | 325 | 0.041 | |
| rhythmic behavior | GO:0007622 | 2 | 0.041 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.040 | |
| regulation of interferon gamma production | GO:0032649 | 36 | 0.040 | |
| nucleotide binding oligomerization domain containing 2 signaling pathway | GO:0070431 | 4 | 0.040 | |
| cellular response to lipoteichoic acid | GO:0071223 | 3 | 0.040 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.040 | |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.040 | Human |
| interferon beta secretion | GO:0035546 | 1 | 0.039 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.039 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.039 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.039 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.039 | Human |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 49 | 0.039 | |
| dephosphorylation | GO:0016311 | 209 | 0.039 | |
| positive regulation of mhc class i biosynthetic process | GO:0045345 | 4 | 0.038 | Human |
| leukocyte activation involved in immune response | GO:0002366 | 30 | 0.038 | |
| regulation of secretion | GO:0051046 | 194 | 0.038 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.038 | |
| positive regulation of interleukin 1 beta secretion | GO:0050718 | 11 | 0.038 | |
| positive regulation of transport | GO:0051050 | 336 | 0.037 | |
| mapk cascade | GO:0000165 | 288 | 0.037 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.037 | |
| positive regulation of defense response | GO:0031349 | 87 | 0.037 | |
| cell activation involved in immune response | GO:0002263 | 30 | 0.037 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.036 | Human |
| lymphocyte activation involved in immune response | GO:0002285 | 20 | 0.036 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.036 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.036 | |
| spermatid development | GO:0007286 | 4 | 0.036 | |
| regulation of cd4 positive alpha beta t cell differentiation | GO:0043370 | 3 | 0.036 | |
| positive regulation of secretion | GO:0051047 | 116 | 0.036 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.036 | |
| regulation of serotonin secretion | GO:0014062 | 1 | 0.035 | |
| oogenesis | GO:0048477 | 2 | 0.035 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.035 | |
| regulation of ion transmembrane transport | GO:0034765 | 132 | 0.035 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.035 | |
| intracellular receptor signaling pathway | GO:0030522 | 104 | 0.035 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.035 | |
| toll like receptor 2 signaling pathway | GO:0034134 | 4 | 0.034 | |
| negative regulation of interleukin 12 secretion | GO:2001183 | 1 | 0.034 | |
| regulation of lymphocyte activation | GO:0051249 | 103 | 0.034 | |
| immune response inhibiting cell surface receptor signaling pathway | GO:0002767 | 4 | 0.034 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.034 | Human |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.034 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.033 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.033 | |
| negative regulation of secretion by cell | GO:1903531 | 52 | 0.033 | Human |
| regulation of t cell activation | GO:0050863 | 77 | 0.033 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.033 | Human |
| regulation of cell activation | GO:0050865 | 125 | 0.033 | |
| serotonin secretion | GO:0001820 | 1 | 0.032 | |
| regulation of cytokine secretion | GO:0050707 | 57 | 0.032 | |
| regulation of t helper cell differentiation | GO:0045622 | 3 | 0.032 | |
| positive regulation of tumor necrosis factor production | GO:0032760 | 21 | 0.032 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.032 | |
| fc receptor mediated inhibitory signaling pathway | GO:0002774 | 2 | 0.032 | |
| female gamete generation | GO:0007292 | 2 | 0.032 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.032 | |
| t helper 1 cell differentiation | GO:0045063 | 1 | 0.032 | |
| regulation of leukocyte differentiation | GO:1902105 | 61 | 0.031 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 39 | 0.031 | |
| regulation of tumor necrosis factor production | GO:0032680 | 43 | 0.031 | |
| positive regulation of alpha beta t cell differentiation | GO:0046638 | 4 | 0.031 | |
| regulation of cytokine mediated signaling pathway | GO:0001959 | 41 | 0.031 | Human |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.031 | Human |
| regulation of protein secretion | GO:0050708 | 86 | 0.031 | |
| positive regulation of t cell proliferation | GO:0042102 | 33 | 0.031 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.031 | |
| antigen receptor mediated signaling pathway | GO:0050851 | 38 | 0.030 | |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 26 | 0.030 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.030 | |
| regulation of mhc class i biosynthetic process | GO:0045343 | 4 | 0.030 | Human |
| memory | GO:0007613 | 3 | 0.030 | |
| divalent inorganic cation transport | GO:0072511 | 158 | 0.030 | |
| positive regulation of chemokine production | GO:0032722 | 22 | 0.030 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.030 | |
| spermatid differentiation | GO:0048515 | 4 | 0.029 | |
| positive regulation of stress activated protein kinase signaling cascade | GO:0070304 | 61 | 0.029 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.029 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.029 | |
| regulation of metal ion transport | GO:0010959 | 120 | 0.029 | |
| positive regulation of interferon gamma production | GO:0032729 | 26 | 0.029 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.029 | Human |
| cell development | GO:0048468 | 328 | 0.029 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.029 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.029 | |
| t helper cell differentiation | GO:0042093 | 4 | 0.029 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.029 | |
| cell morphogenesis | GO:0000902 | 296 | 0.029 | |
| anion transport | GO:0006820 | 161 | 0.028 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.028 | |
| negative regulation of dendritic cell apoptotic process | GO:2000669 | 3 | 0.028 | |
| negative regulation of dendritic cell differentiation | GO:2001199 | 2 | 0.028 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.028 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.028 | |
| cytokine production involved in immune response | GO:0002367 | 27 | 0.028 | |
| positive regulation of cytokine mediated signaling pathway | GO:0001961 | 12 | 0.028 | Human |
| detection of external biotic stimulus | GO:0098581 | 19 | 0.028 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.028 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.027 | |
| circadian sleep wake cycle | GO:0042745 | 2 | 0.027 | |
| regulation of interleukin 10 secretion | GO:2001179 | 4 | 0.027 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.027 | |
| negative regulation of transport | GO:0051051 | 176 | 0.027 | Human |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.027 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.027 | Human |
| circadian behavior | GO:0048512 | 2 | 0.027 | |
| circadian sleep wake cycle process | GO:0022410 | 2 | 0.027 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.027 | |
| protein localization to organelle | GO:0033365 | 280 | 0.027 | Human |
| activation of cysteine type endopeptidase activity | GO:0097202 | 57 | 0.026 | |
| single organism cell adhesion | GO:0098602 | 179 | 0.026 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.026 | |
| myoblast fusion | GO:0007520 | 1 | 0.026 | |
| small molecule biosynthetic process | GO:0044283 | 157 | 0.026 | |
| viral life cycle | GO:0019058 | 132 | 0.026 | |
| viral process | GO:0016032 | 146 | 0.026 | |
| regulation of leukocyte proliferation | GO:0070663 | 67 | 0.026 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.026 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.026 | |
| t cell activation involved in immune response | GO:0002286 | 13 | 0.026 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.025 | |
| regulation of type i interferon production | GO:0032479 | 26 | 0.025 | |
| t cell receptor signaling pathway | GO:0050852 | 21 | 0.025 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.025 | Human |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.025 | |
| gamma delta t cell activation | GO:0046629 | 3 | 0.025 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.025 | |
| regulation of osteoclast development | GO:2001204 | 1 | 0.025 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.025 | Human |
| negative regulation of interferon gamma biosynthetic process | GO:0045077 | 1 | 0.025 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 39 | 0.025 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.025 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.024 | Human |
| programmed necrotic cell death | GO:0097300 | 18 | 0.024 | |
| regulation of transmembrane transport | GO:0034762 | 139 | 0.024 | |
| tumor necrosis factor production | GO:0032640 | 43 | 0.024 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.024 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.024 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 60 | 0.024 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 29 | 0.024 | |
| negative regulation of t cell mediated cytotoxicity | GO:0001915 | 1 | 0.024 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 207 | 0.024 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 94 | 0.024 | |
| syncytium formation by plasma membrane fusion | GO:0000768 | 2 | 0.024 | |
| membrane hyperpolarization | GO:0060081 | 1 | 0.024 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.024 | Human |
| regulation of cell cycle arrest | GO:0071156 | 36 | 0.024 | |
| interleukin 1 beta secretion | GO:0050702 | 15 | 0.024 | |
| regulation of alpha beta t cell activation | GO:0046634 | 13 | 0.024 | |
| positive regulation of cytolysis | GO:0045919 | 3 | 0.024 | |
| negative regulation of immune response | GO:0050777 | 40 | 0.024 | Human |
| regulation of leukocyte apoptotic process | GO:2000106 | 25 | 0.023 | |
| cation transport | GO:0006812 | 331 | 0.023 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.023 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.023 | |
| wnt signaling pathway | GO:0016055 | 156 | 0.023 | |
| interleukin 8 production | GO:0032637 | 51 | 0.023 | Human |
| actin filament based process | GO:0030029 | 224 | 0.023 | |
| single organism cellular localization | GO:1902580 | 332 | 0.023 | Human |
| regulation of dephosphorylation | GO:0035303 | 96 | 0.023 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 37 | 0.023 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.023 | |
| regulation of cd8 positive alpha beta t cell activation | GO:2001185 | 2 | 0.023 | |
| regulation of interleukin 8 production | GO:0032677 | 49 | 0.023 | Human |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.023 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.023 | |
| interferon gamma biosynthetic process | GO:0042095 | 8 | 0.023 | |
| system process | GO:0003008 | 349 | 0.023 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.023 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.023 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.022 | |
| positive regulation of mononuclear cell proliferation | GO:0032946 | 47 | 0.022 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.022 | |
| taxis | GO:0042330 | 157 | 0.022 | |
| midgut development | GO:0007494 | 1 | 0.022 | |
| organic hydroxy compound transport | GO:0015850 | 63 | 0.022 | |
| gamma delta t cell activation involved in immune response | GO:0002290 | 1 | 0.022 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.022 | |
| regulation of response to cytokine stimulus | GO:0060759 | 46 | 0.022 | Human |
| phospholipase c activating g protein coupled receptor signaling pathway | GO:0007200 | 15 | 0.022 | |
| negative regulation of interleukin 10 production | GO:0032693 | 7 | 0.022 | |
| protein targeting | GO:0006605 | 187 | 0.022 | Human |
| negative regulation of protein secretion | GO:0050709 | 29 | 0.022 | Human |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.022 | Human |
| t cell tolerance induction | GO:0002517 | 4 | 0.022 | |
| type i interferon production | GO:0032606 | 27 | 0.022 | |
| leukocyte apoptotic process | GO:0071887 | 31 | 0.022 | |
| t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell | GO:0002291 | 4 | 0.022 | |
| cytokine biosynthetic process | GO:0042089 | 37 | 0.022 | Human |
| positive regulation of t cell differentiation | GO:0045582 | 11 | 0.022 | |
| positive regulation of secretion by cell | GO:1903532 | 108 | 0.022 | |
| negative regulation of calcium ion transport | GO:0051926 | 19 | 0.021 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.021 | |
| regulation of defense response to virus by host | GO:0050691 | 22 | 0.021 | |
| nervous system development | GO:0007399 | 293 | 0.021 | |
| regulation of phosphatase activity | GO:0010921 | 81 | 0.021 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.021 | Human |
| regulation of regulatory t cell differentiation | GO:0045589 | 4 | 0.021 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.021 | |
| zymogen activation | GO:0031638 | 70 | 0.021 | |
| leukocyte proliferation | GO:0070661 | 74 | 0.021 | |
| regulation of locomotion | GO:0040012 | 329 | 0.021 | |
| response to fungus | GO:0009620 | 4 | 0.021 | |
| atp metabolic process | GO:0046034 | 176 | 0.021 | |
| positive regulation of gamma delta t cell activation | GO:0046645 | 1 | 0.021 | |
| t cell proliferation | GO:0042098 | 45 | 0.021 | |
| neurological system process | GO:0050877 | 163 | 0.021 | |
| regulation of t cell proliferation | GO:0042129 | 42 | 0.021 | |
| positive regulation of response to cytokine stimulus | GO:0060760 | 13 | 0.021 | Human |
| oxidation reduction process | GO:0055114 | 396 | 0.020 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.020 | Human |
| regulation of cell cycle process | GO:0010564 | 266 | 0.020 | |
| cell projection organization | GO:0030030 | 252 | 0.020 | |
| lymphocyte differentiation | GO:0030098 | 35 | 0.020 | |
| t cell differentiation | GO:0030217 | 29 | 0.020 | |
| locomotory behavior | GO:0007626 | 1 | 0.020 | |
| negative regulation of transforming growth factor beta secretion | GO:2001202 | 1 | 0.020 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.020 | |
| regulation of t cell differentiation | GO:0045580 | 19 | 0.020 | |
| regulation of interleukin 1 beta secretion | GO:0050706 | 12 | 0.020 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.020 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.020 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.020 | |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 44 | 0.020 | |
| regulation of vesicle mediated transport | GO:0060627 | 130 | 0.020 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.020 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.020 | |
| autophagy | GO:0006914 | 88 | 0.020 | |
| ion homeostasis | GO:0050801 | 230 | 0.020 | |
| regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell | GO:2001188 | 2 | 0.020 | |
| peripheral nervous system development | GO:0007422 | 2 | 0.019 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.019 | |
| cellular homeostasis | GO:0019725 | 196 | 0.019 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.019 | Human |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.019 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.019 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.019 | |
| nuclear transport | GO:0051169 | 179 | 0.019 | Human |
| reactive nitrogen species metabolic process | GO:2001057 | 3 | 0.019 | |
| response to oxygen levels | GO:0070482 | 100 | 0.019 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.019 | |
| response to dsrna | GO:0043331 | 25 | 0.019 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.019 | |
| interferon beta production | GO:0032608 | 23 | 0.019 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.019 | |
| neuron remodeling | GO:0016322 | 2 | 0.019 | |
| regulation of transforming growth factor beta secretion | GO:2001201 | 1 | 0.019 | |
| positive regulation of myeloid leukocyte differentiation | GO:0002763 | 24 | 0.019 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.019 | |
| mononuclear cell proliferation | GO:0032943 | 71 | 0.019 | |
| regulation of cell motility | GO:2000145 | 299 | 0.019 | |
| rna interference | GO:0016246 | 4 | 0.019 | |
| developmental programmed cell death | GO:0010623 | 3 | 0.018 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.018 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.018 | |
| regulation of lymphocyte differentiation | GO:0045619 | 22 | 0.018 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.018 | Human |
| cellular ion homeostasis | GO:0006873 | 168 | 0.018 | |
| regulation of lymphocyte proliferation | GO:0050670 | 64 | 0.018 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.018 | |
| cellular amide metabolic process | GO:0043603 | 69 | 0.018 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.018 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.018 | |
| immature t cell proliferation | GO:0033079 | 1 | 0.018 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.018 | |
| necroptotic process | GO:0070266 | 16 | 0.018 | |
| single organism membrane organization | GO:0044802 | 268 | 0.018 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.018 | |
| protein autoprocessing | GO:0016540 | 4 | 0.018 | |
| positive regulation of interleukin 8 production | GO:0032757 | 36 | 0.018 | Human |
| positive regulation of cd4 positive alpha beta t cell activation | GO:2000516 | 3 | 0.018 | |
| single organismal cell cell adhesion | GO:0016337 | 148 | 0.018 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.018 | |
| interspecies interaction between organisms | GO:0044419 | 156 | 0.018 | |
| positive regulation of jnk cascade | GO:0046330 | 52 | 0.018 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.017 | |
| hindbrain development | GO:0030902 | 3 | 0.017 | |
| osteoclast development | GO:0036035 | 2 | 0.017 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.017 | |
| single organism nuclear import | GO:1902593 | 104 | 0.017 | Human |
| positive regulation of regulatory t cell differentiation | GO:0045591 | 3 | 0.017 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.017 | |
| membrane organization | GO:0061024 | 292 | 0.017 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.017 | |
| response to interleukin 1 | GO:0070555 | 47 | 0.017 | |
| negative regulation of osteoclast development | GO:2001205 | 1 | 0.017 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.017 | |
| regulation of viral process | GO:0050792 | 103 | 0.017 | |
| transforming growth factor beta secretion | GO:0038044 | 1 | 0.017 | |
| lipid metabolic process | GO:0006629 | 381 | 0.017 | |
| compound eye development | GO:0048749 | 1 | 0.017 | |
| negative regulation of protein transport | GO:0051224 | 75 | 0.017 | Human |
| sleep | GO:0030431 | 2 | 0.017 | |
| positive regulation of behavior | GO:0048520 | 60 | 0.017 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.017 | |
| negative regulation of interferon beta secretion | GO:0035548 | 1 | 0.017 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.017 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.017 | |
| leukocyte migration | GO:0050900 | 107 | 0.017 | |
| sequestering of metal ion | GO:0051238 | 24 | 0.017 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.017 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.016 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 158 | 0.016 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.016 | |
| trail activated apoptotic signaling pathway | GO:0036462 | 4 | 0.016 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.016 | |
| neurotransmitter secretion | GO:0007269 | 4 | 0.016 | |
| regulation of chemokine production | GO:0032642 | 31 | 0.016 | |