| dephosphorylation | GO:0016311 | 209 | 0.999 | |
| negative regulation of phosphatase activity | GO:0010923 | 61 | 0.998 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.997 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.992 | |
| copulation | GO:0007620 | 1 | 0.987 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.975 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.969 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.961 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.961 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.957 | |
| regulation of dephosphorylation | GO:0035303 | 96 | 0.953 | |
| protein processing | GO:0016485 | 226 | 0.952 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.952 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.943 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.942 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.938 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.920 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.919 | |
| cell division | GO:0051301 | 168 | 0.914 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.914 | |
| cellular homeostasis | GO:0019725 | 196 | 0.904 | |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.903 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.887 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.880 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.879 | |
| protein dephosphorylation | GO:0006470 | 81 | 0.878 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.875 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.873 | |
| insemination | GO:0007320 | 1 | 0.864 | |
| neuron differentiation | GO:0030182 | 138 | 0.863 | |
| limbic system development | GO:0021761 | 3 | 0.856 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 43 | 0.850 | Rat |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.839 | Rat |
| cell morphogenesis | GO:0000902 | 296 | 0.824 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.816 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.800 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.800 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.797 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.793 | |
| cell projection organization | GO:0030030 | 252 | 0.790 | |
| organelle fission | GO:0048285 | 149 | 0.760 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.753 | |
| generation of precursor metabolites and energy | GO:0006091 | 68 | 0.747 | Rat |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.746 | |
| oogenesis | GO:0048477 | 2 | 0.736 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.734 | |
| adult locomotory behavior | GO:0008344 | 1 | 0.734 | |
| chromosome segregation | GO:0007059 | 114 | 0.733 | |
| chemical homeostasis | GO:0048878 | 306 | 0.729 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.723 | |
| regulation of synaptic plasticity | GO:0048167 | 3 | 0.722 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.713 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.713 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.711 | Mouse |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.707 | |
| protein maturation | GO:0051604 | 233 | 0.705 | |
| organelle assembly | GO:0070925 | 176 | 0.705 | |
| mapk cascade | GO:0000165 | 288 | 0.700 | |
| system process | GO:0003008 | 349 | 0.693 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.685 | |
| cell development | GO:0048468 | 328 | 0.685 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.681 | |
| oxidation reduction process | GO:0055114 | 396 | 0.678 | Rat |
| ras protein signal transduction | GO:0007265 | 73 | 0.676 | |
| single organism membrane organization | GO:0044802 | 268 | 0.670 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.655 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.648 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.637 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 99 | 0.636 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.624 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.622 | |
| chromatin modification | GO:0016568 | 298 | 0.620 | |
| cell adhesion | GO:0007155 | 325 | 0.608 | Human |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.604 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.600 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.599 | |
| dna integrity checkpoint | GO:0031570 | 71 | 0.596 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.585 | |
| regulation of growth | GO:0040008 | 165 | 0.580 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.579 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.578 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.568 | |
| regulation of cell motility | GO:2000145 | 299 | 0.567 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.564 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.555 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.555 | Rat |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.555 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.551 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.548 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.544 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.540 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 89 | 0.532 | |
| regulation of mitotic metaphase anaphase transition | GO:0030071 | 26 | 0.529 | |
| post embryonic development | GO:0009791 | 2 | 0.526 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.520 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.518 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.515 | Mouse |
| peptidyl threonine phosphorylation | GO:0018107 | 41 | 0.515 | |
| tube morphogenesis | GO:0035239 | 95 | 0.508 | Mouse |
| regulation of proteasomal protein catabolic process | GO:0061136 | 87 | 0.506 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.500 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.499 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.486 | |
| regulation of chromosome segregation | GO:0051983 | 44 | 0.484 | |
| organ morphogenesis | GO:0009887 | 147 | 0.483 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.481 | Mouse |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.479 | |
| neuron projection development | GO:0031175 | 106 | 0.477 | |
| metal ion transport | GO:0030001 | 272 | 0.475 | |
| regulation of transporter activity | GO:0032409 | 82 | 0.474 | |
| response to radiation | GO:0009314 | 151 | 0.464 | Mouse |
| protein catabolic process | GO:0030163 | 325 | 0.460 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 71 | 0.460 | |
| glycogen metabolic process | GO:0005977 | 22 | 0.457 | Rat |
| regulation of metal ion transport | GO:0010959 | 120 | 0.456 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.445 | |
| neuron development | GO:0048666 | 113 | 0.443 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.441 | Mouse |
| visual learning | GO:0008542 | 1 | 0.441 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.431 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.430 | |
| regulation of cell growth | GO:0001558 | 135 | 0.424 | |
| embryo development | GO:0009790 | 123 | 0.423 | |
| meiotic nuclear division | GO:0007126 | 10 | 0.422 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.417 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.414 | |
| growth | GO:0040007 | 202 | 0.412 | |
| taxis | GO:0042330 | 157 | 0.412 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.410 | |
| actin filament based process | GO:0030029 | 224 | 0.404 | |
| locomotory behavior | GO:0007626 | 1 | 0.388 | |
| regulation of cell division | GO:0051302 | 116 | 0.387 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.386 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.385 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.382 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.380 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.361 | |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.355 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.352 | |
| cation homeostasis | GO:0055080 | 189 | 0.351 | |
| nervous system development | GO:0007399 | 293 | 0.350 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.345 | Mouse |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.345 | |
| regulation of phosphatase activity | GO:0010921 | 81 | 0.342 | |
| chromatin organization | GO:0006325 | 351 | 0.338 | |
| cellular carbohydrate metabolic process | GO:0044262 | 84 | 0.330 | Rat |
| cell part morphogenesis | GO:0032990 | 137 | 0.329 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.322 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.320 | |
| regulation of mitotic sister chromatid separation | GO:0010965 | 27 | 0.318 | |
| regulation of protein processing | GO:0070613 | 150 | 0.315 | |
| female gamete generation | GO:0007292 | 2 | 0.313 | |
| protein polymerization | GO:0051258 | 71 | 0.306 | |
| energy reserve metabolic process | GO:0006112 | 22 | 0.291 | Rat |
| protein ubiquitination | GO:0016567 | 314 | 0.289 | |
| regulation of cell projection organization | GO:0031344 | 107 | 0.281 | |
| tube development | GO:0035295 | 125 | 0.281 | Mouse |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.279 | |
| negative regulation of cell growth | GO:0030308 | 83 | 0.279 | |
| chromosome separation | GO:0051304 | 23 | 0.273 | |
| calcium ion transport | GO:0006816 | 147 | 0.270 | |
| generation of neurons | GO:0048699 | 152 | 0.268 | |
| associative learning | GO:0008306 | 1 | 0.266 | |
| neuron projection morphogenesis | GO:0048812 | 50 | 0.264 | |
| positive regulation of response to dna damage stimulus | GO:2001022 | 43 | 0.260 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.255 | |
| positive regulation of protein complex assembly | GO:0031334 | 86 | 0.255 | |
| regulation of locomotion | GO:0040012 | 329 | 0.254 | |
| neurological system process | GO:0050877 | 163 | 0.251 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.250 | |
| single organism cellular localization | GO:1902580 | 332 | 0.250 | |
| cellular glucan metabolic process | GO:0006073 | 22 | 0.249 | Rat |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.248 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.241 | |
| nuclear division | GO:0000280 | 128 | 0.238 | |
| organelle localization | GO:0051640 | 84 | 0.237 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.233 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.227 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.226 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.226 | |
| positive regulation of transport | GO:0051050 | 336 | 0.224 | |
| endocytosis | GO:0006897 | 159 | 0.223 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.219 | |
| negative regulation of growth | GO:0045926 | 97 | 0.218 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.217 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.217 | |
| defense response | GO:0006952 | 315 | 0.214 | |
| divalent inorganic cation transport | GO:0072511 | 158 | 0.212 | |
| regulation of intracellular protein transport | GO:0033157 | 123 | 0.212 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.211 | |
| peptidyl threonine modification | GO:0018210 | 45 | 0.211 | |
| cell growth | GO:0016049 | 160 | 0.210 | |
| cytokinesis | GO:0000910 | 96 | 0.207 | |
| metaphase anaphase transition of mitotic cell cycle | GO:0007091 | 21 | 0.204 | |
| regulation of vesicle mediated transport | GO:0060627 | 130 | 0.197 | |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.194 | |
| regulation of cellular component size | GO:0032535 | 82 | 0.192 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.191 | |
| neurogenesis | GO:0022008 | 169 | 0.190 | |
| cell morphogenesis involved in neuron differentiation | GO:0048667 | 44 | 0.185 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.182 | Mouse |
| regulation of gene expression epigenetic | GO:0040029 | 73 | 0.181 | |
| negative regulation of proteasomal protein catabolic process | GO:1901799 | 32 | 0.181 | |
| ion homeostasis | GO:0050801 | 230 | 0.178 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.176 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.176 | |
| biological adhesion | GO:0022610 | 331 | 0.174 | Human |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.173 | |
| response to cytokine | GO:0034097 | 232 | 0.173 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.169 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.167 | |
| regulation of calcium ion transport | GO:0051924 | 79 | 0.167 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.166 | |
| histone modification | GO:0016570 | 251 | 0.166 | |
| negative regulation of transport | GO:0051051 | 176 | 0.164 | |
| regulation of mitochondrion organization | GO:0010821 | 54 | 0.164 | |
| behavior | GO:0007610 | 112 | 0.164 | |
| mitotic nuclear division | GO:0007067 | 119 | 0.164 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 44 | 0.163 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.162 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.158 | |
| regulation of protein transport | GO:0051223 | 213 | 0.158 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.155 | |
| membrane organization | GO:0061024 | 292 | 0.153 | |
| signal transduction in response to dna damage | GO:0042770 | 57 | 0.152 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.149 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 75 | 0.149 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.149 | |
| regulation of epithelial cell proliferation | GO:0050678 | 113 | 0.148 | |
| reproductive process | GO:0022414 | 106 | 0.147 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.146 | |
| apoptotic mitochondrial changes | GO:0008637 | 57 | 0.143 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.143 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.141 | |
| actin filament organization | GO:0007015 | 128 | 0.140 | |
| calcium ion homeostasis | GO:0055074 | 122 | 0.139 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.138 | |
| atp metabolic process | GO:0046034 | 176 | 0.137 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.133 | |
| meiotic cell cycle | GO:0051321 | 13 | 0.132 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.132 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.131 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.131 | |
| regulation of neurogenesis | GO:0050767 | 82 | 0.131 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.130 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.129 | |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.129 | |
| regulation of nervous system development | GO:0051960 | 88 | 0.128 | |
| response to metal ion | GO:0010038 | 84 | 0.128 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.124 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.124 | |
| cation transport | GO:0006812 | 331 | 0.121 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.120 | |
| oocyte differentiation | GO:0009994 | 2 | 0.120 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.119 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.118 | |
| regulation of ion transmembrane transport | GO:0034765 | 132 | 0.117 | |
| receptor mediated endocytosis | GO:0006898 | 84 | 0.117 | |
| regulation of transmembrane transporter activity | GO:0022898 | 74 | 0.117 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.116 | |
| g2 dna damage checkpoint | GO:0031572 | 26 | 0.116 | |
| negative regulation of calcium ion transport | GO:0051926 | 19 | 0.115 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 57 | 0.114 | |
| axonogenesis | GO:0007409 | 31 | 0.114 | |
| telencephalon development | GO:0021537 | 17 | 0.113 | |
| regulation of nuclear division | GO:0051783 | 65 | 0.112 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.112 | |
| regulation of blood circulation | GO:1903522 | 59 | 0.111 | |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.110 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.110 | |
| mitotic sister chromatid segregation | GO:0000070 | 53 | 0.109 | |
| regulation of transmembrane transport | GO:0034762 | 139 | 0.106 | |
| adult behavior | GO:0030534 | 18 | 0.105 | |
| dna replication | GO:0006260 | 116 | 0.105 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.103 | |
| central nervous system development | GO:0007417 | 123 | 0.102 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.102 | |
| carbohydrate catabolic process | GO:0016052 | 36 | 0.100 | Rat |
| brain development | GO:0007420 | 97 | 0.100 | |
| meiotic chromosome segregation | GO:0045132 | 4 | 0.100 | |
| oocyte development | GO:0048599 | 1 | 0.099 | |
| regulation of metaphase anaphase transition of cell cycle | GO:1902099 | 26 | 0.099 | |
| dendrite morphogenesis | GO:0048813 | 14 | 0.099 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.098 | |
| muscle system process | GO:0003012 | 81 | 0.097 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.097 | |
| epithelium development | GO:0060429 | 227 | 0.096 | Mouse |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.096 | |
| single organism reproductive process | GO:0044702 | 98 | 0.095 | |
| regulation of dendrite development | GO:0050773 | 18 | 0.095 | |
| negative regulation of sister chromatid segregation | GO:0033046 | 17 | 0.095 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.094 | |
| regulation of map kinase activity | GO:0043405 | 108 | 0.093 | |
| regulation of meiosis | GO:0040020 | 3 | 0.093 | |
| intracellular protein transport | GO:0006886 | 270 | 0.092 | |
| protein kinase b signaling | GO:0043491 | 69 | 0.091 | |
| sensory organ development | GO:0007423 | 52 | 0.090 | |
| reproduction | GO:0000003 | 63 | 0.090 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.090 | |
| pigmentation | GO:0043473 | 22 | 0.090 | |
| monovalent inorganic cation transport | GO:0015672 | 128 | 0.088 | |
| dna templated transcription termination | GO:0006353 | 3 | 0.087 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.086 | Mouse |
| regulation of nucleocytoplasmic transport | GO:0046822 | 98 | 0.085 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.085 | |
| establishment of organelle localization | GO:0051656 | 59 | 0.085 | |
| negative regulation of dephosphorylation | GO:0035305 | 63 | 0.084 | |
| regulation of ubiquitin protein transferase activity | GO:0051438 | 28 | 0.083 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.082 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.082 | |
| dna repair | GO:0006281 | 198 | 0.081 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.080 | |
| cardiovascular system development | GO:0072358 | 262 | 0.079 | Zebrafish |
| regulation of actin filament based process | GO:0032970 | 141 | 0.078 | |
| actin polymerization or depolymerization | GO:0008154 | 56 | 0.078 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.078 | Mouse |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 156 | 0.077 | |
| regulation of ion transport | GO:0043269 | 189 | 0.076 | |
| positive regulation of secretion | GO:0051047 | 116 | 0.076 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.075 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 38 | 0.075 | |
| signal transduction by p53 class mediator | GO:0072331 | 72 | 0.073 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.072 | |
| reproductive structure development | GO:0048608 | 55 | 0.071 | |
| amine metabolic process | GO:0009308 | 44 | 0.070 | |
| secretion by cell | GO:0032940 | 226 | 0.069 | |
| chemotaxis | GO:0006935 | 157 | 0.068 | |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 28 | 0.068 | |
| regulation of protein localization | GO:0032880 | 296 | 0.067 | |
| regulation of cell development | GO:0060284 | 161 | 0.066 | |
| dendrite development | GO:0016358 | 24 | 0.065 | |
| protein targeting | GO:0006605 | 187 | 0.064 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.064 | |
| positive regulation of cell development | GO:0010720 | 92 | 0.063 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 37 | 0.062 | |
| negative regulation of ion transport | GO:0043271 | 39 | 0.062 | |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.062 | |
| regulation of chromosome organization | GO:0033044 | 103 | 0.062 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.060 | |
| viral process | GO:0016032 | 146 | 0.059 | |
| mitotic sister chromatid separation | GO:0051306 | 18 | 0.059 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.059 | |
| regulation of protein dephosphorylation | GO:0035304 | 18 | 0.059 | |
| establishment of protein localization to plasma membrane | GO:0090002 | 68 | 0.059 | |
| sequestering of metal ion | GO:0051238 | 24 | 0.058 | |
| positive regulation of dna repair | GO:0045739 | 25 | 0.058 | |
| multicellular organism reproduction | GO:0032504 | 42 | 0.058 | |
| regulation of centriole replication | GO:0046599 | 7 | 0.057 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.057 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.056 | |
| renal system development | GO:0072001 | 63 | 0.056 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.056 | Zebrafish |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 158 | 0.055 | |
| regulation of cell migration | GO:0030334 | 289 | 0.055 | |
| maintenance of location | GO:0051235 | 112 | 0.054 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 50 | 0.054 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.054 | |
| eye development | GO:0001654 | 42 | 0.053 | |
| t cell homeostasis | GO:0043029 | 3 | 0.053 | |
| actin filament polymerization | GO:0030041 | 45 | 0.052 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.052 | |
| regulation of membrane potential | GO:0042391 | 95 | 0.051 | |
| negative regulation of cell division | GO:0051782 | 31 | 0.051 | |
| developmental growth | GO:0048589 | 48 | 0.050 | |
| plasma membrane organization | GO:0007009 | 115 | 0.050 | |
| gland development | GO:0048732 | 48 | 0.050 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.049 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.049 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.049 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.048 | |
| mitotic dna integrity checkpoint | GO:0044774 | 30 | 0.048 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.048 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.048 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 34 | 0.047 | |
| lipid metabolic process | GO:0006629 | 381 | 0.047 | |
| monosaccharide metabolic process | GO:0005996 | 74 | 0.047 | Rat |
| epithelial cell proliferation | GO:0050673 | 128 | 0.047 | |
| blood vessel morphogenesis | GO:0048514 | 162 | 0.047 | Zebrafish |
| central nervous system neuron development | GO:0021954 | 7 | 0.046 | |
| anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process | GO:0031145 | 25 | 0.046 | |
| response to light stimulus | GO:0009416 | 87 | 0.046 | Mouse |
| head development | GO:0060322 | 108 | 0.046 | |
| protein localization to organelle | GO:0033365 | 280 | 0.046 | |
| negative regulation of mapk cascade | GO:0043409 | 56 | 0.045 | |
| cognition | GO:0050890 | 43 | 0.045 | |
| regulation of protein kinase b signaling | GO:0051896 | 61 | 0.044 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.044 | |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 83 | 0.044 | |
| molting cycle | GO:0042303 | 28 | 0.044 | |
| immune system development | GO:0002520 | 195 | 0.043 | |
| golgi vesicle transport | GO:0048193 | 80 | 0.043 | |
| development of primary sexual characteristics | GO:0045137 | 35 | 0.043 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.042 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.042 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.042 | |
| rna interference | GO:0016246 | 4 | 0.041 | |
| positive regulation of growth | GO:0045927 | 58 | 0.040 | |
| negative regulation of protein modification by small protein conjugation or removal | GO:1903321 | 41 | 0.039 | |
| release of cytochrome c from mitochondria | GO:0001836 | 35 | 0.039 | |
| histone phosphorylation | GO:0016572 | 16 | 0.039 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.039 | |
| central nervous system neuron axonogenesis | GO:0021955 | 3 | 0.038 | |
| leukocyte apoptotic process | GO:0071887 | 31 | 0.038 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.038 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 81 | 0.037 | |
| positive regulation of secretion by cell | GO:1903532 | 108 | 0.037 | |
| sister chromatid segregation | GO:0000819 | 54 | 0.036 | |
| reproductive system development | GO:0061458 | 56 | 0.035 | |
| protein import | GO:0017038 | 130 | 0.035 | |
| regulation of dna repair | GO:0006282 | 47 | 0.035 | |
| negative regulation of response to dna damage stimulus | GO:2001021 | 33 | 0.035 | |
| developmental programmed cell death | GO:0010623 | 3 | 0.035 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.035 | |
| response to inorganic substance | GO:0010035 | 127 | 0.035 | |
| single organism membrane fusion | GO:0044801 | 37 | 0.035 | |
| protein acylation | GO:0043543 | 138 | 0.035 | |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.034 | |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.034 | |
| innate immune response | GO:0045087 | 178 | 0.033 | |
| fatty acid metabolic process | GO:0006631 | 115 | 0.033 | |
| cerebral cortex gabaergic interneuron differentiation | GO:0021892 | 1 | 0.033 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.033 | |
| negative regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043154 | 46 | 0.033 | |
| regulation of mitotic cell cycle spindle assembly checkpoint | GO:0090266 | 8 | 0.033 | |
| rna processing | GO:0006396 | 255 | 0.032 | |
| multi organism cellular process | GO:0044764 | 156 | 0.032 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.032 | |
| regulation of sister chromatid segregation | GO:0033045 | 27 | 0.032 | |
| regulation of mitosis | GO:0007088 | 63 | 0.031 | |
| negative regulation of chromosome organization | GO:2001251 | 48 | 0.031 | |
| glucose metabolic process | GO:0006006 | 45 | 0.031 | Rat |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 119 | 0.031 | |
| regulation of heart rate | GO:0002027 | 38 | 0.031 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.031 | |
| cellular process involved in reproduction in multicellular organism | GO:0022412 | 15 | 0.030 | |
| regulation of dendrite morphogenesis | GO:0048814 | 11 | 0.030 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.030 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.030 | |
| rhythmic process | GO:0048511 | 31 | 0.030 | |
| cell aging | GO:0007569 | 52 | 0.030 | |
| glycoprotein metabolic process | GO:0009100 | 110 | 0.029 | |
| response to endoplasmic reticulum stress | GO:0034976 | 49 | 0.029 | |
| negative regulation of nucleocytoplasmic transport | GO:0046823 | 37 | 0.029 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.029 | |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 45 | 0.029 | |
| regulation of anatomical structure size | GO:0090066 | 101 | 0.029 | |
| positive regulation of developmental growth | GO:0048639 | 16 | 0.029 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 35 | 0.028 | |
| cellular polysaccharide metabolic process | GO:0044264 | 27 | 0.028 | Rat |
| regulation of glycogen metabolic process | GO:0070873 | 15 | 0.028 | Rat |
| metaphase anaphase transition of cell cycle | GO:0044784 | 21 | 0.028 | |
| cellular calcium ion homeostasis | GO:0006874 | 117 | 0.027 | |
| cell cell signaling | GO:0007267 | 155 | 0.027 | |
| mesenchyme development | GO:0060485 | 59 | 0.027 | |
| regulation of excitatory postsynaptic membrane potential | GO:0060079 | 1 | 0.027 | |
| urogenital system development | GO:0001655 | 65 | 0.027 | |
| cardiac muscle cell contraction | GO:0086003 | 4 | 0.027 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.027 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 125 | 0.026 | |
| phospholipid metabolic process | GO:0006644 | 99 | 0.026 | |
| transmembrane transport | GO:0055085 | 399 | 0.026 | |
| glycolipid metabolic process | GO:0006664 | 27 | 0.026 | |
| regulation of protein targeting | GO:1903533 | 91 | 0.026 | |
| regulation of membrane permeability | GO:0090559 | 25 | 0.026 | |
| regulation of leukocyte proliferation | GO:0070663 | 67 | 0.025 | |
| negative regulation of calcium ion transmembrane transport | GO:1903170 | 11 | 0.025 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.025 | |
| heart morphogenesis | GO:0003007 | 48 | 0.025 | |
| regulation of cell shape | GO:0008360 | 48 | 0.025 | |
| microtubule based process | GO:0007017 | 210 | 0.025 | |
| regulation of hormone secretion | GO:0046883 | 57 | 0.024 | |
| termination of rna polymerase ii transcription | GO:0006369 | 1 | 0.024 | |
| replication fork processing | GO:0031297 | 13 | 0.024 | |
| glycerophospholipid metabolic process | GO:0006650 | 84 | 0.024 | |
| segmentation | GO:0035282 | 4 | 0.023 | |
| negative regulation of jnk cascade | GO:0046329 | 16 | 0.023 | |
| liposaccharide metabolic process | GO:1903509 | 27 | 0.023 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.023 | |
| axon development | GO:0061564 | 34 | 0.023 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.023 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.022 | |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.022 | |
| negative regulation of metaphase anaphase transition of cell cycle | GO:1902100 | 17 | 0.022 | |
| response to growth factor | GO:0070848 | 205 | 0.022 | |
| regulation of generation of precursor metabolites and energy | GO:0043467 | 27 | 0.022 | Rat |
| regulation of sequestering of calcium ion | GO:0051282 | 41 | 0.022 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.022 | |
| somatic muscle development | GO:0007525 | 1 | 0.021 | |
| central nervous system projection neuron axonogenesis | GO:0021952 | 3 | 0.021 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 72 | 0.021 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.021 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.021 | |
| regulation of actin filament polymerization | GO:0030833 | 50 | 0.021 | |
| regulation of voltage gated calcium channel activity | GO:1901385 | 7 | 0.021 | |
| negative regulation of protein transport | GO:0051224 | 75 | 0.021 | |
| protein targeting to nucleus | GO:0044744 | 104 | 0.021 | |
