| epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway | GO:0035625 | 4 | 0.603 | |
| regulation of cell migration | GO:0030334 | 289 | 0.586 | Human |
| monovalent inorganic cation transport | GO:0015672 | 128 | 0.419 | |
| regulation of excitatory postsynaptic membrane potential | GO:0060079 | 1 | 0.396 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.294 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.263 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.222 | Human |
| metal ion transport | GO:0030001 | 272 | 0.196 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.189 | |
| potassium ion transport | GO:0006813 | 62 | 0.174 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.174 | Human |
| positive regulation of vasodilation | GO:0045909 | 4 | 0.173 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.167 | |
| protein dephosphorylation | GO:0006470 | 81 | 0.166 | Human Rat Fly |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.165 | |
| phospholipase c activating adrenergic receptor signaling pathway | GO:0071882 | 1 | 0.162 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.161 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.157 | Human Zebrafish |
| cation transport | GO:0006812 | 331 | 0.156 | |
| amine metabolic process | GO:0009308 | 44 | 0.155 | |
| cell chemotaxis | GO:0060326 | 112 | 0.153 | |
| positive regulation of leukocyte chemotaxis | GO:0002690 | 38 | 0.146 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.131 | |
| regulation of bone mineralization | GO:0030500 | 29 | 0.130 | |
| positive regulation of phosphatidylinositol 3 kinase signaling | GO:0014068 | 28 | 0.127 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.125 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.117 | Human Zebrafish |
| phosphatidylinositol mediated signaling | GO:0048015 | 55 | 0.114 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.113 | |
| cell adhesion | GO:0007155 | 325 | 0.109 | Human |
| activation of mapk activity by adrenergic receptor signaling pathway | GO:0071883 | 3 | 0.109 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.107 | |
| positive regulation of ras gtpase activity | GO:0032320 | 117 | 0.106 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.104 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 156 | 0.104 | |
| rho protein signal transduction | GO:0007266 | 26 | 0.103 | |
| negative regulation of insulin secretion involved in cellular response to glucose stimulus | GO:0061179 | 1 | 0.101 | |
| biological adhesion | GO:0022610 | 331 | 0.099 | Human |
| regulation of neuronal synaptic plasticity | GO:0048168 | 1 | 0.098 | |
| cell matrix adhesion | GO:0007160 | 85 | 0.097 | |
| receptor transactivation | GO:0035624 | 4 | 0.096 | |
| toll like receptor 2 signaling pathway | GO:0034134 | 4 | 0.096 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.096 | Human |
| post embryonic development | GO:0009791 | 2 | 0.092 | |
| regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:2000058 | 7 | 0.091 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.091 | Human Zebrafish |
| negative regulation of immune system process | GO:0002683 | 136 | 0.089 | |
| regulation of cell motility | GO:2000145 | 299 | 0.088 | Human |
| regulation of leukocyte migration | GO:0002685 | 63 | 0.087 | |
| nucleotide biosynthetic process | GO:0009165 | 109 | 0.086 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.084 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.084 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 79 | 0.083 | |
| regulation of phosphatidylinositol 3 kinase signaling | GO:0014066 | 35 | 0.082 | |
| defense response | GO:0006952 | 315 | 0.082 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.081 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.081 | Mouse |
| positive regulation of chemotaxis | GO:0050921 | 57 | 0.081 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.081 | Mouse |
| regulation of cyclic nucleotide metabolic process | GO:0030799 | 63 | 0.080 | |
| negative regulation of cell adhesion | GO:0007162 | 64 | 0.080 | Human |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.078 | |
| epithelium migration | GO:0090132 | 119 | 0.078 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.078 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.078 | |
| regulation of cgmp mediated signaling | GO:0010752 | 1 | 0.077 | |
| regulation of erbb signaling pathway | GO:1901184 | 27 | 0.077 | |
| regulation of postsynaptic membrane potential | GO:0060078 | 1 | 0.076 | |
| negative regulation of cell migration | GO:0030336 | 102 | 0.076 | |
| regulation of potassium ion transport | GO:0043266 | 24 | 0.076 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.075 | Human |
| regulation of macrophage chemotaxis | GO:0010758 | 4 | 0.074 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.073 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.073 | Human |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.073 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.072 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.071 | |
| vasodilation | GO:0042311 | 4 | 0.071 | |
| positive regulation of cellular component movement | GO:0051272 | 181 | 0.069 | Human |
| regulation of metal ion transport | GO:0010959 | 120 | 0.069 | |
| epithelium development | GO:0060429 | 227 | 0.069 | Zebrafish |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.069 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.067 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.067 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.066 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 109 | 0.066 | |
| positive regulation of cell adhesion | GO:0045785 | 84 | 0.065 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.062 | |
| regulation of vasodilation | GO:0042312 | 4 | 0.062 | |
| regulation of membrane potential | GO:0042391 | 95 | 0.061 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.061 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.061 | |
| response to lipid | GO:0033993 | 206 | 0.061 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.060 | |
| regulation of calcium ion transport into cytosol | GO:0010522 | 33 | 0.060 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.060 | |
| secretion | GO:0046903 | 254 | 0.060 | |
| gtp catabolic process | GO:0006184 | 237 | 0.059 | |
| positive regulation of behavior | GO:0048520 | 60 | 0.059 | |
| immune system development | GO:0002520 | 195 | 0.058 | Human |
| regulation of behavior | GO:0050795 | 82 | 0.058 | |
| regulation of myeloid leukocyte mediated immunity | GO:0002886 | 4 | 0.057 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.057 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.057 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.055 | |
| immune response | GO:0006955 | 307 | 0.055 | Human |
| cellular ion homeostasis | GO:0006873 | 168 | 0.055 | |
| regulation of lymphocyte chemotaxis | GO:1901623 | 12 | 0.055 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.054 | |
| innate immune response | GO:0045087 | 178 | 0.052 | |
| regulation of immune response | GO:0050776 | 201 | 0.052 | Human |
| positive regulation of rac gtpase activity | GO:0032855 | 31 | 0.052 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.052 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.052 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.051 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.051 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.051 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.051 | |
| maintenance of location | GO:0051235 | 112 | 0.051 | |
| purine nucleotide biosynthetic process | GO:0006164 | 84 | 0.051 | |
| tissue migration | GO:0090130 | 119 | 0.050 | |
| cyclic nucleotide biosynthetic process | GO:0009190 | 61 | 0.050 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.050 | |
| cellular response to organic cyclic compound | GO:0071407 | 127 | 0.050 | |
| sequestering of metal ion | GO:0051238 | 24 | 0.049 | |
| positive regulation of epidermal growth factor receptor signaling pathway | GO:0045742 | 11 | 0.049 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 75 | 0.049 | |
| phosphatidylinositol 3 kinase signaling | GO:0014065 | 48 | 0.048 | |
| adenylate cyclase inhibiting serotonin receptor signaling pathway | GO:0007198 | 2 | 0.047 | |
| regulation of synaptic plasticity | GO:0048167 | 3 | 0.047 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.046 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.046 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.046 | Mouse |
| regulation of chemotaxis | GO:0050920 | 74 | 0.046 | |
| sequestering of calcium ion | GO:0051208 | 17 | 0.045 | |
| regulation of actin filament based process | GO:0032970 | 141 | 0.045 | |
| behavior | GO:0007610 | 112 | 0.045 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.045 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 78 | 0.045 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.045 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.044 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.044 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.044 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.044 | Mouse |
| positive regulation of lymphocyte migration | GO:2000403 | 16 | 0.044 | |
| calcium mediated signaling | GO:0019722 | 44 | 0.044 | |
| membrane protein proteolysis | GO:0033619 | 38 | 0.043 | |
| regulation of biomineral tissue development | GO:0070167 | 31 | 0.043 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.043 | |
| regeneration | GO:0031099 | 4 | 0.042 | |
| positive regulation of endothelial cell migration | GO:0010595 | 39 | 0.042 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.042 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.041 | |
| regulation of cyclic nucleotide biosynthetic process | GO:0030802 | 49 | 0.040 | |
| gtp metabolic process | GO:0046039 | 239 | 0.040 | |
| cell cycle g1 s phase transition | GO:0044843 | 80 | 0.040 | |
| regulation of growth rate | GO:0040009 | 1 | 0.040 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.040 | |
| sodium ion transport | GO:0006814 | 61 | 0.040 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 3 | 0.040 | |
| positive regulation of locomotion | GO:0040017 | 186 | 0.040 | Human |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 108 | 0.039 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.039 | |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.039 | |
| positive regulation of protein kinase b signaling | GO:0051897 | 42 | 0.039 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.039 | |
| positive regulation of response to external stimulus | GO:0032103 | 88 | 0.039 | |
| behavioral response to ethanol | GO:0048149 | 2 | 0.038 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 99 | 0.038 | |
| cyclic nucleotide metabolic process | GO:0009187 | 82 | 0.038 | |
| anatomical structure homeostasis | GO:0060249 | 100 | 0.038 | |
| positive regulation of rho gtpase activity | GO:0032321 | 56 | 0.038 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.038 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.038 | |
| negative regulation of cell motility | GO:2000146 | 104 | 0.037 | |
| positive regulation of synaptic transmission | GO:0050806 | 4 | 0.037 | |
| regulation of defense response | GO:0031347 | 154 | 0.037 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.037 | Human |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.036 | Human |
| immune response activating signal transduction | GO:0002757 | 90 | 0.036 | Human |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.036 | |
| response to molecule of bacterial origin | GO:0002237 | 82 | 0.036 | |
| regulation of epithelial cell migration | GO:0010632 | 93 | 0.036 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.035 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.035 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.035 | |
| positive regulation of protein polymerization | GO:0032273 | 45 | 0.035 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.035 | |
| neurogenesis | GO:0022008 | 169 | 0.035 | Rat Fly |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.035 | |
| negative regulation of homeostatic process | GO:0032845 | 59 | 0.034 | |
| spermatid differentiation | GO:0048515 | 4 | 0.034 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.034 | Human |
| regulation of locomotion | GO:0040012 | 329 | 0.034 | Human |
| erbb signaling pathway | GO:0038127 | 44 | 0.034 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.034 | |
| cardiac muscle adaptation | GO:0014887 | 4 | 0.034 | |
| associative learning | GO:0008306 | 1 | 0.034 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.033 | |
| ribose phosphate biosynthetic process | GO:0046390 | 82 | 0.033 | |
| response to drug | GO:0042493 | 81 | 0.033 | |
| protein ubiquitination | GO:0016567 | 314 | 0.033 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 89 | 0.033 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.033 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.033 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.032 | |
| adenylate cyclase inhibiting adrenergic receptor signaling pathway | GO:0071881 | 1 | 0.032 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.032 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.032 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.032 | |
| regulation of cell adhesion mediated by integrin | GO:0033628 | 22 | 0.032 | |
| actin filament organization | GO:0007015 | 128 | 0.031 | |
| ion homeostasis | GO:0050801 | 230 | 0.031 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.031 | |
| cell substrate adhesion | GO:0031589 | 132 | 0.031 | |
| desensitization of g protein coupled receptor protein signaling pathway by arrestin | GO:0002032 | 2 | 0.031 | |
| lymphocyte activation | GO:0046649 | 133 | 0.031 | Human |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.031 | Human |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 119 | 0.031 | |
| positive regulation of oxidoreductase activity | GO:0051353 | 26 | 0.031 | |
| positive regulation of jnk cascade | GO:0046330 | 52 | 0.031 | |
| intestine smooth muscle contraction | GO:0014827 | 2 | 0.031 | |
| bone mineralization | GO:0030282 | 34 | 0.031 | |
| cilium morphogenesis | GO:0060271 | 75 | 0.030 | |
| regulation of protein polymerization | GO:0032271 | 63 | 0.030 | |
| regulation of leukocyte chemotaxis | GO:0002688 | 46 | 0.030 | |
| ameboidal type cell migration | GO:0001667 | 135 | 0.030 | |
| regulation of stress activated mapk cascade | GO:0032872 | 84 | 0.030 | |
| response to camp | GO:0051591 | 25 | 0.030 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 60 | 0.030 | |
| rap protein signal transduction | GO:0032486 | 7 | 0.030 | |
| chemical homeostasis | GO:0048878 | 306 | 0.030 | |
| regulation of jnk cascade | GO:0046328 | 73 | 0.029 | |
| negative regulation of cellular component movement | GO:0051271 | 106 | 0.029 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.029 | |
| long term synaptic potentiation | GO:0060291 | 1 | 0.029 | |
| regulation of cell projection organization | GO:0031344 | 107 | 0.029 | |
| regulation of purine nucleotide biosynthetic process | GO:1900371 | 50 | 0.029 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.029 | |
| leukocyte chemotaxis | GO:0030595 | 76 | 0.029 | |
| negative regulation of cell cell adhesion | GO:0022408 | 27 | 0.029 | |
| calcium ion transport into cytosol | GO:0060402 | 48 | 0.029 | |
| coagulation | GO:0050817 | 78 | 0.029 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.029 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.029 | |
| tissue regeneration | GO:0042246 | 3 | 0.028 | |
| positive regulation of protein tyrosine kinase activity | GO:0061098 | 24 | 0.028 | |
| protein secretion | GO:0009306 | 98 | 0.028 | |
| negative regulation of cell substrate adhesion | GO:0010812 | 24 | 0.028 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.028 | Human |
| response to other organism | GO:0051707 | 261 | 0.028 | |
| regulation of cell growth | GO:0001558 | 135 | 0.028 | |
| neurotrophin signaling pathway | GO:0038179 | 8 | 0.028 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.028 | |
| neurotrophin trk receptor signaling pathway | GO:0048011 | 4 | 0.028 | |
| regulation of lymphocyte migration | GO:2000401 | 22 | 0.027 | |
| adult locomotory behavior | GO:0008344 | 1 | 0.027 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.027 | |
| epithelial cell development | GO:0002064 | 34 | 0.027 | |
| negative regulation of cytokine production | GO:0001818 | 82 | 0.027 | |
| response to hormone | GO:0009725 | 175 | 0.027 | Mouse |
| response to external biotic stimulus | GO:0043207 | 261 | 0.027 | |
| second messenger mediated signaling | GO:0019932 | 78 | 0.026 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.026 | |
| regulation of nucleotide biosynthetic process | GO:0030808 | 50 | 0.026 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.026 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.026 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.026 | |
| reactive nitrogen species metabolic process | GO:2001057 | 3 | 0.026 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.026 | |
| spermatid development | GO:0007286 | 4 | 0.026 | |
| generation of neurons | GO:0048699 | 152 | 0.026 | Rat Fly |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.025 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.025 | |
| regulation of ion homeostasis | GO:2000021 | 73 | 0.025 | |
| semaphorin plexin signaling pathway | GO:0071526 | 4 | 0.025 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.025 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.025 | |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.025 | |
| regulation of epithelial cell proliferation | GO:0050678 | 113 | 0.025 | |
| growth | GO:0040007 | 202 | 0.025 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 4 | 0.025 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.025 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.025 | Human |
| actin filament based process | GO:0030029 | 224 | 0.025 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.025 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.025 | |
| regulation of ras gtpase activity | GO:0032318 | 128 | 0.024 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.024 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.024 | Human |
| cell cycle checkpoint | GO:0000075 | 117 | 0.024 | |
| inflammatory response | GO:0006954 | 79 | 0.024 | |
| protein catabolic process | GO:0030163 | 325 | 0.024 | |
| stress activated mapk cascade | GO:0051403 | 93 | 0.024 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.024 | |
| activation of janus kinase activity | GO:0042976 | 7 | 0.024 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.024 | Mouse |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.024 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.024 | |
| membrane protein ectodomain proteolysis | GO:0006509 | 33 | 0.023 | |
| epidermal growth factor receptor signaling pathway | GO:0007173 | 39 | 0.023 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.023 | |
| positive regulation of monooxygenase activity | GO:0032770 | 14 | 0.023 | |
| regulation of growth | GO:0040008 | 165 | 0.023 | |
| regulation of ossification | GO:0030278 | 58 | 0.023 | |
| purine containing compound biosynthetic process | GO:0072522 | 88 | 0.023 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.023 | |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 85 | 0.023 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.022 | |
| tissue homeostasis | GO:0001894 | 63 | 0.022 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.022 | |
| positive regulation of phosphatidylinositol biosynthetic process | GO:0010513 | 3 | 0.022 | |
| regulation of cell substrate adhesion | GO:0010810 | 68 | 0.022 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.022 | |
| sensory perception of sound | GO:0007605 | 37 | 0.022 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.022 | |
| circulatory system development | GO:0072359 | 262 | 0.022 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.022 | |
| negative regulation of platelet aggregation | GO:0090331 | 3 | 0.021 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 4 | 0.021 | |
| response to organophosphorus | GO:0046683 | 41 | 0.021 | |
| short term memory | GO:0007614 | 1 | 0.021 | |
| mapk cascade | GO:0000165 | 288 | 0.021 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.021 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.021 | |
| single organismal cell cell adhesion | GO:0016337 | 148 | 0.021 | |
| response to hydrogen peroxide | GO:0042542 | 40 | 0.021 | |
| negative regulation of locomotion | GO:0040013 | 118 | 0.021 | |
| neuron development | GO:0048666 | 113 | 0.021 | Fly |
| epithelial cell differentiation | GO:0030855 | 141 | 0.021 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.021 | |
| tissue morphogenesis | GO:0048729 | 96 | 0.021 | Zebrafish |
| taxis | GO:0042330 | 157 | 0.021 | Fly |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.021 | |
| positive regulation of transport | GO:0051050 | 336 | 0.021 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.021 | |
| regulation of inositol phosphate biosynthetic process | GO:0010919 | 3 | 0.021 | |
| response to wounding | GO:0009611 | 168 | 0.021 | |
| positive regulation of protein ubiquitination | GO:0031398 | 53 | 0.020 | |
| lymphocyte migration | GO:0072676 | 28 | 0.020 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.020 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.020 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.020 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.020 | |
| response to lithium ion | GO:0010226 | 2 | 0.020 | |
| regulation of body fluid levels | GO:0050878 | 99 | 0.020 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.020 | |
| response to growth factor | GO:0070848 | 205 | 0.020 | |
| regulation of blood coagulation | GO:0030193 | 42 | 0.020 | |
| dephosphorylation | GO:0016311 | 209 | 0.020 | Human Rat Fly |
| epithelial tube branching involved in lung morphogenesis | GO:0060441 | 4 | 0.019 | |
| multicellular organismal homeostasis | GO:0048871 | 67 | 0.019 | |
| keratinization | GO:0031424 | 2 | 0.019 | |
| platelet derived growth factor receptor beta signaling pathway | GO:0035791 | 4 | 0.019 | |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.019 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.019 | |
| cell division | GO:0051301 | 168 | 0.019 | |
| positive regulation of cell substrate adhesion | GO:0010811 | 37 | 0.019 | |
| regulation of exocytosis | GO:0017157 | 46 | 0.019 | |
| regulation of clathrin mediated endocytosis | GO:2000369 | 4 | 0.019 | |
| salivary gland morphogenesis | GO:0007435 | 4 | 0.019 | |
| cyclic purine nucleotide metabolic process | GO:0052652 | 60 | 0.019 | |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 61 | 0.019 | |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.019 | |
| regulation of inflammatory response | GO:0050727 | 46 | 0.019 | |
| regulation of protein kinase b signaling | GO:0051896 | 61 | 0.019 | |
| locomotory behavior | GO:0007626 | 1 | 0.019 | |
| single organism cell adhesion | GO:0098602 | 179 | 0.019 | |
| negative regulation of sequestering of calcium ion | GO:0051283 | 41 | 0.018 | |
| cell morphogenesis | GO:0000902 | 296 | 0.018 | Fly |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.018 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.018 | |
| positive regulation of leukocyte migration | GO:0002687 | 46 | 0.018 | |
| nuclear transport | GO:0051169 | 179 | 0.018 | |
| protein kinase c signaling | GO:0070528 | 17 | 0.018 | |
| response to estradiol | GO:0032355 | 23 | 0.018 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.018 | Fly |
| regulation of actin cytoskeleton organization | GO:0032956 | 116 | 0.018 | |
| oocyte development | GO:0048599 | 1 | 0.018 | |
| peptidyl tyrosine dephosphorylation | GO:0035335 | 36 | 0.018 | Human Rat Fly |
| negative regulation of developmental process | GO:0051093 | 247 | 0.018 | |
| positive regulation of lipase activity | GO:0060193 | 28 | 0.018 | |
| memory | GO:0007613 | 3 | 0.018 | |
| negative regulation of homotypic cell cell adhesion | GO:0034111 | 3 | 0.018 | |
| release of sequestered calcium ion into cytosol | GO:0051209 | 41 | 0.018 | |
| regulation of stress activated protein kinase signaling cascade | GO:0070302 | 85 | 0.018 | |
| positive regulation of cell matrix adhesion | GO:0001954 | 23 | 0.018 | |
| regulation of cell cycle g1 s phase transition | GO:1902806 | 42 | 0.018 | |
| regulation of protein tyrosine kinase activity | GO:0061097 | 36 | 0.018 | |
| regulation of endocytosis | GO:0030100 | 72 | 0.018 | |
| glycerolipid metabolic process | GO:0046486 | 107 | 0.018 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.018 | |
| ribonucleotide biosynthetic process | GO:0009260 | 81 | 0.018 | |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 82 | 0.018 | |
| positive regulation of actin filament polymerization | GO:0030838 | 38 | 0.017 | |
| myeloid leukocyte differentiation | GO:0002573 | 60 | 0.017 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.017 | Mouse |
| calcium ion transport | GO:0006816 | 147 | 0.017 | |
| cellular homeostasis | GO:0019725 | 196 | 0.017 | |
| regulation of natural killer cell differentiation | GO:0032823 | 2 | 0.017 | |
| regulation of cytokine production | GO:0001817 | 232 | 0.017 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.017 | |
| positive regulation of cell growth | GO:0030307 | 48 | 0.017 | |
| protein maturation | GO:0051604 | 233 | 0.017 | |
| negative regulation of blood pressure | GO:0045776 | 3 | 0.017 | |
| tissue remodeling | GO:0048771 | 16 | 0.017 | |
| response to steroid hormone | GO:0048545 | 80 | 0.017 | |
| protein modification by small protein removal | GO:0070646 | 92 | 0.017 | |
| regulation of release of sequestered calcium ion into cytosol | GO:0051279 | 27 | 0.017 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.016 | |
| regulation of endothelial cell migration | GO:0010594 | 67 | 0.016 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.016 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.016 | |
| ossification | GO:0001503 | 121 | 0.016 | |
| positive regulation of erbb signaling pathway | GO:1901186 | 11 | 0.016 | |
| negative regulation of defense response | GO:0031348 | 47 | 0.016 | |
| oocyte differentiation | GO:0009994 | 2 | 0.016 | |
| cell projection organization | GO:0030030 | 252 | 0.016 | Fly |
| regulation of map kinase activity | GO:0043405 | 108 | 0.016 | |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.016 | |
| cellular response to tumor necrosis factor | GO:0071356 | 63 | 0.016 | |
| regulation of cell matrix adhesion | GO:0001952 | 42 | 0.016 | |
| lung growth | GO:0060437 | 2 | 0.016 | |
| response to fungus | GO:0009620 | 4 | 0.016 | |
| response to cytokine | GO:0034097 | 232 | 0.016 | |
| regulation of rap protein signal transduction | GO:0032487 | 9 | 0.016 | |
| regulation of epidermal growth factor receptor signaling pathway | GO:0042058 | 27 | 0.016 | |
| negative regulation of hemostasis | GO:1900047 | 22 | 0.016 | |
| morphogenesis of an epithelium | GO:0002009 | 60 | 0.016 | Zebrafish |
| regulation of jun kinase activity | GO:0043506 | 27 | 0.016 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.016 | Rat |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.016 | |
| single organism membrane organization | GO:0044802 | 268 | 0.016 | |
| leukocyte differentiation | GO:0002521 | 98 | 0.016 | |
| cellular response to acid chemical | GO:0071229 | 44 | 0.016 | |
| positive regulation of camp biosynthetic process | GO:0030819 | 35 | 0.016 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.015 | |
| positive regulation of stress activated protein kinase signaling cascade | GO:0070304 | 61 | 0.015 | |
| regulation of receptor activity | GO:0010469 | 47 | 0.015 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.015 | Mouse |
| positive regulation of epithelial cell migration | GO:0010634 | 55 | 0.015 | |
| actin filament polymerization | GO:0030041 | 45 | 0.015 | |
| response to bacterium | GO:0009617 | 144 | 0.015 | |
| cellular defense response | GO:0006968 | 2 | 0.015 | |
| regulation of insulin secretion | GO:0050796 | 33 | 0.015 | |
| regulation of g protein coupled receptor protein signaling pathway | GO:0008277 | 35 | 0.015 | |
| regulation of rho gtpase activity | GO:0032319 | 66 | 0.015 | |
| humoral immune response | GO:0006959 | 49 | 0.015 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.015 | |
| female genitalia development | GO:0030540 | 2 | 0.015 | |
| developmental growth | GO:0048589 | 48 | 0.015 | |
| positive regulation of jak stat cascade | GO:0046427 | 35 | 0.015 | |
| trivalent inorganic cation transport | GO:0072512 | 4 | 0.015 | |
| regulation of binding | GO:0051098 | 111 | 0.015 | |
| atp metabolic process | GO:0046034 | 176 | 0.015 | |
| small molecule biosynthetic process | GO:0044283 | 157 | 0.015 | |
| negative regulation of cell growth | GO:0030308 | 83 | 0.015 | |
| intracellular protein transport | GO:0006886 | 270 | 0.015 | |
| response to extracellular stimulus | GO:0009991 | 85 | 0.015 | |
| protein targeting | GO:0006605 | 187 | 0.015 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.015 | Rat |
| negative regulation of muscle contraction | GO:0045932 | 3 | 0.015 | |
| positive regulation of rap gtpase activity | GO:0032854 | 8 | 0.015 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.015 | |
| regulation of monooxygenase activity | GO:0032768 | 22 | 0.015 | |
| oogenesis | GO:0048477 | 2 | 0.015 | |
| cell growth | GO:0016049 | 160 | 0.015 | |
| hemopoiesis | GO:0030097 | 180 | 0.015 | Human |
| regulation of short term neuronal synaptic plasticity | GO:0048172 | 1 | 0.015 | |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.015 | |
| regulation of osteoblast differentiation | GO:0045667 | 38 | 0.014 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.014 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.014 | |
| sensory perception of mechanical stimulus | GO:0050954 | 37 | 0.014 | |
| prostate gland development | GO:0030850 | 3 | 0.014 | |
| blood vessel development | GO:0001568 | 172 | 0.014 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 37 | 0.014 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.014 | |
| regulation of t cell chemotaxis | GO:0010819 | 7 | 0.014 | |
