IMP: Integrative Multi-species Prediction

Homo sapiens

0 known processes

RPS27A

ribosomal protein S27a

(Aliases: UBCEP1,S27A,UBCEP80,UBC,CEP80,UBA80)

MIM: 191343
HGNC: 10417
Ensembl: ENSG00000143947
Entrez: 6233
HPRD: 01878
UniProtKB: P62979
UniProtKB: B2RDW1

Process Predictions
Disease Predictions

RPS27A biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
post embryonic development	GO:0009791	2	0.985	Worm
determination of adult lifespan	GO:0008340	2	0.665
spindle elongation	GO:0051231	4	0.545
spindle organization	GO:0007051	53	0.517
mitotic spindle elongation	GO:0000022	4	0.498
mitotic cell cycle	GO:0000278	326	0.448
molting cycle	GO:0042303	28	0.390	Worm
microtubule cytoskeleton organization	GO:0000226	176	0.386
microtubule organizing center organization	GO:0031023	62	0.362
cytoplasmic translation	GO:0002181	8	0.294
microtubule based process	GO:0007017	210	0.263
ribosome biogenesis	GO:0042254	48	0.225
multicellular organismal aging	GO:0010259	3	0.222
ncrna metabolic process	GO:0034660	108	0.202
embryo development	GO:0009790	123	0.148	Worm
rrna processing	GO:0006364	35	0.135
ribonucleoprotein complex biogenesis	GO:0022613	116	0.121
ncrna processing	GO:0034470	83	0.117
mitotic cell cycle process	GO:1903047	286	0.117
oogenesis	GO:0048477	2	0.115
mitotic spindle organization	GO:0007052	27	0.099
rrna metabolic process	GO:0016072	40	0.095
maturation of ssu rrna	GO:0030490	3	0.094
regulation of cellular response to stress	GO:0080135	244	0.092
positive regulation of p38mapk cascade	GO:1900745	8	0.084
cellular macromolecular complex assembly	GO:0034622	324	0.080
female gamete generation	GO:0007292	2	0.078
cytoplasmic transport	GO:0016482	379	0.078
translation	GO:0006412	132	0.066
positive regulation of protein phosphorylation	GO:0001934	313	0.066
centrosome duplication	GO:0051298	28	0.056
neurogenesis	GO:0022008	169	0.050	Worm
regulation of growth	GO:0040008	165	0.047
regulation of cell cycle process	GO:0010564	266	0.046
cell projection organization	GO:0030030	252	0.045	Worm
atp metabolic process	GO:0046034	176	0.043
gonad development	GO:0008406	34	0.041
activation of mapkkk activity	GO:0000185	7	0.040
establishment of protein localization to organelle	GO:0072594	172	0.040
positive regulation of proteolysis	GO:0045862	142	0.040
organophosphate catabolic process	GO:0046434	430	0.039
oocyte development	GO:0048599	1	0.037
reproduction	GO:0000003	63	0.037	Worm
cellular macromolecule catabolic process	GO:0044265	380	0.037
mitochondrion organization	GO:0007005	156	0.036
signal transduction by phosphorylation	GO:0023014	297	0.036
mapk cascade	GO:0000165	288	0.036
positive regulation of apoptotic process	GO:0043065	246	0.035
anterior posterior axis specification embryo	GO:0008595	2	0.034
jnk cascade	GO:0007254	80	0.033
dna repair	GO:0006281	198	0.032
regulation of oocyte development	GO:0060281	1	0.032
chromatin organization	GO:0006325	351	0.031
nervous system development	GO:0007399	293	0.030	Worm
neuron differentiation	GO:0030182	138	0.030	Worm
neuron projection development	GO:0031175	106	0.029	Worm
gene silencing	GO:0016458	49	0.028
maintenance of location	GO:0051235	112	0.027
single organism cellular localization	GO:1902580	332	0.026
reproductive process	GO:0022414	106	0.026	Worm
nucleoside phosphate catabolic process	GO:1901292	412	0.026
protein localization to organelle	GO:0033365	280	0.024
protein targeting	GO:0006605	187	0.023
regulation of cellular amino acid metabolic process	GO:0006521	6	0.023
embryo development ending in birth or egg hatching	GO:0009792	34	0.023	Worm
purine nucleoside catabolic process	GO:0006152	398	0.023
regulation of kinase activity	GO:0043549	314	0.023
response to abiotic stimulus	GO:0009628	336	0.023
lipid localization	GO:0010876	106	0.022
neuron development	GO:0048666	113	0.022	Worm
activation of protein kinase activity	GO:0032147	90	0.022
cellular component morphogenesis	GO:0032989	314	0.022	Worm
positive regulation of programmed cell death	GO:0043068	249	0.021
cellular response to dna damage stimulus	GO:0006974	379	0.021
histone modification	GO:0016570	251	0.021
oocyte differentiation	GO:0009994	2	0.021
aging	GO:0007568	66	0.020
cell development	GO:0048468	328	0.020	Worm
positive regulation of jnk cascade	GO:0046330	52	0.020
positive regulation of stress activated mapk cascade	GO:0032874	60	0.020
regulation of protein kinase activity	GO:0045859	289	0.020
cell part morphogenesis	GO:0032990	137	0.020	Worm
positive regulation of cell death	GO:0010942	263	0.020
cytochrome complex assembly	GO:0017004	13	0.020
generation of neurons	GO:0048699	152	0.019	Worm
purine ribonucleoside metabolic process	GO:0046128	437	0.019
regulation of transferase activity	GO:0051338	355	0.019
chemical homeostasis	GO:0048878	306	0.019
reproductive structure development	GO:0048608	55	0.018
ribosomal large subunit biogenesis	GO:0042273	10	0.018
centrosome organization	GO:0051297	58	0.017
single organism reproductive process	GO:0044702	98	0.016
negative regulation of phosphate metabolic process	GO:0045936	267	0.016
rna processing	GO:0006396	255	0.016
regulation of gene expression epigenetic	GO:0040029	73	0.015
multicellular organism reproduction	GO:0032504	42	0.015	Worm
regulation of apoptotic signaling pathway	GO:2001233	175	0.015
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.015
regulation of translational elongation	GO:0006448	2	0.015
rna localization	GO:0006403	41	0.015
covalent chromatin modification	GO:0016569	254	0.014
regulation of stress activated mapk cascade	GO:0032872	84	0.014
reproductive system development	GO:0061458	56	0.014
nuclear transport	GO:0051169	179	0.014
posttranscriptional regulation of gene expression	GO:0010608	213	0.014
purine containing compound catabolic process	GO:0072523	411	0.014
positive regulation of phosphorylation	GO:0042327	394	0.014
positive regulation of hydrolase activity	GO:0051345	331	0.013
glycosyl compound catabolic process	GO:1901658	413	0.013
ribonucleotide catabolic process	GO:0009261	405	0.013
anterior posterior axis specification	GO:0009948	2	0.013
positive regulation of protein serine threonine kinase activity	GO:0071902	119	0.013
negative regulation of cell cycle	GO:0045786	193	0.013
gtp metabolic process	GO:0046039	239	0.013
regulation of mitotic cell cycle	GO:0007346	189	0.012
nucleoside catabolic process	GO:0009164	408	0.012
positive regulation of kinase activity	GO:0033674	204	0.012
negative regulation of mitotic cell cycle phase transition	GO:1901991	85	0.012
positive regulation of mapk cascade	GO:0043410	190	0.012
regulation of endopeptidase activity	GO:0052548	170	0.012
myeloid cell differentiation	GO:0030099	117	0.011
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.011
ribonucleoside catabolic process	GO:0042454	406	0.011
negative regulation of programmed cell death	GO:0043069	321	0.011
apoptotic signaling pathway	GO:0097190	268	0.011
nucleoside monophosphate metabolic process	GO:0009123	191	0.011
cell morphogenesis	GO:0000902	296	0.011	Worm
protein localization to membrane	GO:0072657	160	0.010
cellular ketone metabolic process	GO:0042180	80	0.010
sex differentiation	GO:0007548	45	0.010
centrosome cycle	GO:0007098	32	0.010
regulation of immune effector process	GO:0002697	91	0.010
negative regulation of cell cycle process	GO:0010948	121	0.010

RPS27A disease predictions

Disease	DO term ID	Size	Probability
immune system disease	DOID:2914	155	0.269
hematopoietic system disease	DOID:74	100	0.135
anemia	DOID:2355	55	0.060
diamond blackfan anemia	DOID:1339	10	0.060
aplastic anemia	DOID:12449	30	0.060
bone marrow disease	DOID:4961	31	0.060
congenital hypoplastic anemia	DOID:1342	26	0.060
central nervous system disease	DOID:331	186	0.014
nervous system disease	DOID:863	431	0.014

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