| scf dependent proteasomal ubiquitin dependent protein catabolic process | GO:0031146 | 15 | 1.000 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 1.000 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 1.000 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 1.000 | |
| protein ubiquitination | GO:0016567 | 314 | 1.000 | |
| cellular protein catabolic process | GO:0044257 | 261 | 1.000 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 1.000 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.999 | |
| protein catabolic process | GO:0030163 | 325 | 0.999 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.999 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.998 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.997 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.996 | |
| regulation of tor signaling | GO:0032006 | 30 | 0.994 | |
| g2 m transition of mitotic cell cycle | GO:0000086 | 41 | 0.985 | Yeast |
| negative regulation of glial cell proliferation | GO:0060253 | 2 | 0.975 | |
| wnt signaling pathway | GO:0016055 | 156 | 0.972 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.963 | Yeast Worm Fly |
| release of cytoplasmic sequestered nf kappab | GO:0008588 | 4 | 0.949 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.941 | Fly |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.941 | Fly |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.920 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.919 | |
| neuron remodeling | GO:0016322 | 2 | 0.912 | Fly |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 61 | 0.906 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.902 | Worm Fly |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.901 | |
| positive regulation of protein ubiquitination | GO:0031398 | 53 | 0.896 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.893 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.882 | Fly |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.872 | Fly |
| positive regulation of meiotic cell cycle | GO:0051446 | 2 | 0.861 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 78 | 0.846 | Yeast |
| protein monoubiquitination | GO:0006513 | 39 | 0.820 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.812 | Fly |
| determination of adult lifespan | GO:0008340 | 2 | 0.808 | Worm |
| regulation of canonical wnt signaling pathway | GO:0060828 | 88 | 0.807 | |
| somatic stem cell maintenance | GO:0035019 | 4 | 0.803 | |
| negative regulation of wnt signaling pathway | GO:0030178 | 69 | 0.791 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 56 | 0.790 | Fly |
| regulation of mitosis | GO:0007088 | 63 | 0.774 | Yeast |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.762 | Yeast Fly |
| cellular response to hormone stimulus | GO:0032870 | 125 | 0.743 | Fly |
| cellular response to insulin stimulus | GO:0032869 | 41 | 0.730 | Fly |
| post embryonic development | GO:0009791 | 2 | 0.701 | Worm |
| mitotic cell cycle | GO:0000278 | 326 | 0.692 | Yeast Worm Fly |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.675 | |
| negative regulation of tor signaling | GO:0032007 | 11 | 0.667 | |
| response to hormone | GO:0009725 | 175 | 0.666 | Fly |
| regulation of ubiquitin protein transferase activity | GO:0051438 | 28 | 0.659 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.650 | Fly |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.636 | Fly |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.635 | Fly |
| positive regulation of cellular protein catabolic process | GO:1903364 | 37 | 0.631 | |
| cell cycle g2 m phase transition | GO:0044839 | 43 | 0.618 | Yeast |
| protein k48 linked ubiquitination | GO:0070936 | 38 | 0.611 | |
| regulation of cellular component size | GO:0032535 | 82 | 0.597 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.594 | Yeast Worm Fly |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.593 | Worm |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.584 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.583 | Worm Fly |
| canonical wnt signaling pathway involved in negative regulation of apoptotic process | GO:0044336 | 2 | 0.579 | |
| regulation of heart induction | GO:0090381 | 2 | 0.575 | |
| anatomical structure homeostasis | GO:0060249 | 100 | 0.541 | |
| nuclear division | GO:0000280 | 128 | 0.532 | Yeast Worm Fly |
| microtubule based process | GO:0007017 | 210 | 0.523 | Worm Fly |
| nephron tubule epithelial cell differentiation | GO:0072160 | 3 | 0.519 | |
| canonical wnt signaling pathway | GO:0060070 | 116 | 0.518 | |
| tor signaling | GO:0031929 | 39 | 0.515 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.511 | Fly |
| regulation of cell cycle process | GO:0010564 | 266 | 0.505 | Yeast Fly |
| second messenger mediated signaling | GO:0019932 | 78 | 0.482 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.469 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.467 | Yeast |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.460 | Yeast Fly |
| female gamete generation | GO:0007292 | 2 | 0.455 | |
| intracellular protein transport | GO:0006886 | 270 | 0.455 | |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 28 | 0.447 | |
| regulation of protein import into nucleus | GO:0042306 | 78 | 0.438 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.436 | |
| peptide transport | GO:0015833 | 74 | 0.435 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.416 | Worm |
| response to oxygen containing compound | GO:1901700 | 369 | 0.416 | Fly |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.415 | Worm |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.399 | Fly |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.393 | |
| meiotic cell cycle | GO:0051321 | 13 | 0.390 | Worm |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.389 | Fly |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 61 | 0.377 | |
| regulation of protein localization to nucleus | GO:1900180 | 85 | 0.376 | |
| regulation of centrosome cycle | GO:0046605 | 15 | 0.372 | Fly |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.371 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.371 | Fly |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.364 | Fly |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.361 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 37 | 0.351 | Yeast |
| intracellular receptor signaling pathway | GO:0030522 | 104 | 0.350 | |
| cerebral cortex radially oriented cell migration | GO:0021799 | 1 | 0.349 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.329 | |
| mitotic nuclear division | GO:0007067 | 119 | 0.328 | Yeast Fly |
| regulation of microtubule based process | GO:0032886 | 74 | 0.326 | Fly |
| regulation of triglyceride metabolic process | GO:0090207 | 11 | 0.322 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.321 | |
| positive regulation of cell cycle process | GO:0090068 | 106 | 0.321 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 38 | 0.320 | |
| response to light stimulus | GO:0009416 | 87 | 0.315 | |
| negative regulation of gliogenesis | GO:0014014 | 3 | 0.314 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.308 | Worm |
| regulation of peptide transport | GO:0090087 | 62 | 0.289 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.286 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.276 | Fly |
| nf kappab import into nucleus | GO:0042348 | 22 | 0.274 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.270 | |
| metaphase anaphase transition of cell cycle | GO:0044784 | 21 | 0.269 | |
| smoothened signaling pathway | GO:0007224 | 14 | 0.264 | |
| cellular response to lithium ion | GO:0071285 | 2 | 0.252 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.251 | |
| organelle fission | GO:0048285 | 149 | 0.246 | Yeast Worm Fly |
| regulation of intracellular protein transport | GO:0033157 | 123 | 0.233 | |
| neuron differentiation | GO:0030182 | 138 | 0.230 | Fly |
| amide transport | GO:0042886 | 76 | 0.230 | |
| regulation of nf kappab import into nucleus | GO:0042345 | 22 | 0.229 | |
| regulation of glial cell proliferation | GO:0060251 | 4 | 0.227 | |
| response to peptide | GO:1901652 | 65 | 0.225 | Fly |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.224 | |
| response to metal ion | GO:0010038 | 84 | 0.219 | |
| response to virus | GO:0009615 | 126 | 0.214 | |
| camp mediated signaling | GO:0019933 | 23 | 0.213 | |
| cell projection organization | GO:0030030 | 252 | 0.208 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 82 | 0.205 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.203 | Worm |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.202 | |
| cellular response to radiation | GO:0071478 | 65 | 0.194 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.194 | Yeast |
| reproductive system development | GO:0061458 | 56 | 0.193 | Worm |
| regulation of smooth muscle cell proliferation | GO:0048660 | 28 | 0.192 | |
| regulation of protein localization | GO:0032880 | 296 | 0.188 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.188 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 87 | 0.187 | |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.185 | |
| negative regulation of intracellular protein transport | GO:0090317 | 42 | 0.183 | |
| response to insulin | GO:0032868 | 45 | 0.181 | Fly |
| embryonic forelimb morphogenesis | GO:0035115 | 4 | 0.177 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.176 | Fly |
| regulation of chromosome organization | GO:0033044 | 103 | 0.175 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.170 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.168 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.166 | Fly |
| system process | GO:0003008 | 349 | 0.165 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.163 | Fly |
| regulation of nucleocytoplasmic transport | GO:0046822 | 98 | 0.162 | |
| meiosis i | GO:0007127 | 4 | 0.160 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.158 | |
| regulation of microtubule cytoskeleton organization | GO:0070507 | 61 | 0.157 | Fly |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.156 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.153 | Fly |
| cellular response to peptide | GO:1901653 | 59 | 0.152 | Fly |
| histone monoubiquitination | GO:0010390 | 20 | 0.150 | |
| positive regulation of transport | GO:0051050 | 336 | 0.149 | |
| cell death in response to oxidative stress | GO:0036473 | 29 | 0.148 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.148 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.147 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.147 | Worm |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.147 | |
| regulation of anatomical structure size | GO:0090066 | 101 | 0.146 | |
| epithelial cell proliferation | GO:0050673 | 128 | 0.143 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.138 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.138 | |
| negative regulation of smoothened signaling pathway | GO:0045879 | 3 | 0.136 | |
| centrosome cycle | GO:0007098 | 32 | 0.135 | Fly |
| dna replication | GO:0006260 | 116 | 0.135 | Fly |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.133 | |
| positive regulation of intracellular protein transport | GO:0090316 | 76 | 0.132 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.132 | |
| negative regulation of transport | GO:0051051 | 176 | 0.131 | |
| response to peptide hormone | GO:0043434 | 61 | 0.130 | Fly |
| protein localization to organelle | GO:0033365 | 280 | 0.126 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.125 | Worm |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.125 | Fly |
| negative regulation of protein processing | GO:0010955 | 142 | 0.125 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.124 | Fly |
| negative regulation of protein import into nucleus | GO:0042308 | 30 | 0.123 | |
| cell morphogenesis | GO:0000902 | 296 | 0.123 | |
| neurological system process | GO:0050877 | 163 | 0.123 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.122 | |
| negative regulation of protein transport | GO:0051224 | 75 | 0.122 | |
| cerebral cortex radial glia guided migration | GO:0021801 | 1 | 0.120 | |
| cell cycle g1 s phase transition | GO:0044843 | 80 | 0.120 | Yeast |
| generation of neurons | GO:0048699 | 152 | 0.120 | Fly |
| amine metabolic process | GO:0009308 | 44 | 0.120 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.116 | |
| protein targeting | GO:0006605 | 187 | 0.115 | |
| granulocyte differentiation | GO:0030851 | 16 | 0.114 | |
| regulation of cyclin dependent protein serine threonine kinase activity | GO:0000079 | 36 | 0.114 | |
| regulation of metaphase anaphase transition of cell cycle | GO:1902099 | 26 | 0.114 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.113 | |
| negative regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043154 | 46 | 0.111 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.109 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.108 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.107 | Fly |
| regulation of protein processing | GO:0070613 | 150 | 0.107 | |
| regulation of lipid biosynthetic process | GO:0046890 | 47 | 0.107 | |
| negative regulation of camp mediated signaling | GO:0043951 | 4 | 0.107 | |
| positive regulation of glycoprotein metabolic process | GO:1903020 | 8 | 0.104 | |
| histone h2a ubiquitination | GO:0033522 | 17 | 0.103 | |
| organelle assembly | GO:0070925 | 176 | 0.103 | Yeast |
| defense response to virus | GO:0051607 | 71 | 0.103 | |
| autophagic cell death | GO:0048102 | 3 | 0.103 | |
| regulation of protein targeting | GO:1903533 | 91 | 0.101 | |
| stem cell proliferation | GO:0072089 | 25 | 0.099 | |
| organ morphogenesis | GO:0009887 | 147 | 0.099 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.097 | |
| cyclin catabolic process | GO:0008054 | 6 | 0.097 | |
| negative regulation of immune system process | GO:0002683 | 136 | 0.096 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.095 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.095 | |
| negative regulation of epithelial cell proliferation | GO:0050680 | 48 | 0.095 | |
| single organism reproductive process | GO:0044702 | 98 | 0.091 | Worm |
| response to lithium ion | GO:0010226 | 2 | 0.091 | |
| neurogenesis | GO:0022008 | 169 | 0.090 | Fly |
| single organism cellular localization | GO:1902580 | 332 | 0.090 | Worm |
| oogenesis | GO:0048477 | 2 | 0.088 | |
| embryo development | GO:0009790 | 123 | 0.088 | Worm |
| segmentation | GO:0035282 | 4 | 0.087 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.086 | |
| positive regulation of wnt signaling pathway | GO:0030177 | 54 | 0.085 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.084 | Fly |
| neutral lipid metabolic process | GO:0006638 | 27 | 0.084 | |
| positive regulation of proteasomal protein catabolic process | GO:1901800 | 35 | 0.083 | |
| chemical homeostasis | GO:0048878 | 306 | 0.082 | Yeast |
| negative regulation of canonical wnt signaling pathway | GO:0090090 | 55 | 0.081 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.079 | |
| stem cell development | GO:0048864 | 69 | 0.077 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.077 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.076 | Fly |
| negative regulation of mitotic anaphase promoting complex activity | GO:0060564 | 4 | 0.076 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.075 | Fly |
| negative regulation of protein localization to nucleus | GO:1900181 | 34 | 0.075 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.075 | Fly |
| negative regulation of myeloid leukocyte differentiation | GO:0002762 | 16 | 0.074 | |
| cell development | GO:0048468 | 328 | 0.074 | Fly |
| protein neddylation | GO:0045116 | 7 | 0.074 | Yeast |
| multicellular organismal reproductive process | GO:0048609 | 40 | 0.073 | Worm |
| regulation of g1 s transition of mitotic cell cycle | GO:2000045 | 40 | 0.073 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.072 | Fly |
| histone h2a monoubiquitination | GO:0035518 | 11 | 0.071 | |
| response to radiation | GO:0009314 | 151 | 0.071 | |
| cellular response to toxic substance | GO:0097237 | 4 | 0.071 | |
| cerebral cortex cell migration | GO:0021795 | 3 | 0.071 | |
| negative regulation of cytoplasmic transport | GO:1903650 | 46 | 0.070 | |
| blastocyst development | GO:0001824 | 3 | 0.070 | |
| protein destabilization | GO:0031648 | 12 | 0.070 | |
| neuron maturation | GO:0042551 | 5 | 0.068 | Fly |
| regulation of embryonic development | GO:0045995 | 20 | 0.068 | |
| chromatin organization | GO:0006325 | 351 | 0.068 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.067 | |
| receptor mediated endocytosis | GO:0006898 | 84 | 0.066 | Worm |
| regeneration | GO:0031099 | 4 | 0.065 | |
| regulation of triglyceride catabolic process | GO:0010896 | 6 | 0.064 | |
| protein maturation | GO:0051604 | 233 | 0.063 | |
| nervous system development | GO:0007399 | 293 | 0.062 | Fly |
| positive regulation of nf kappab import into nucleus | GO:0042346 | 13 | 0.062 | |
| negative regulation of cysteine type endopeptidase activity | GO:2000117 | 48 | 0.062 | |
| chordate embryonic development | GO:0043009 | 34 | 0.062 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.061 | |
| protein k63 linked ubiquitination | GO:0070534 | 31 | 0.060 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.060 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.060 | |
| stem cell differentiation | GO:0048863 | 93 | 0.059 | |
| small molecule biosynthetic process | GO:0044283 | 157 | 0.059 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.059 | Fly |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 54 | 0.059 | |
| regulation of organelle assembly | GO:1902115 | 40 | 0.058 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.058 | Fly |
| nuclear import | GO:0051170 | 106 | 0.058 | |
| defense response | GO:0006952 | 315 | 0.057 | Worm |
| regulation of mitotic sister chromatid segregation | GO:0033047 | 27 | 0.057 | |
| regulation of protein stability | GO:0031647 | 87 | 0.056 | Fly |
| regulation of kidney development | GO:0090183 | 10 | 0.056 | |
| positive regulation of transcription factor import into nucleus | GO:0042993 | 25 | 0.056 | |
| mitotic dna damage checkpoint | GO:0044773 | 28 | 0.056 | Fly |
| cell fate determination | GO:0001709 | 3 | 0.055 | |
| neutral lipid biosynthetic process | GO:0046460 | 11 | 0.055 | |
| g1 dna damage checkpoint | GO:0044783 | 18 | 0.054 | |
| regulation of smoothened signaling pathway | GO:0008589 | 6 | 0.054 | |
| spindle organization | GO:0007051 | 53 | 0.054 | |
| regulation of intracellular steroid hormone receptor signaling pathway | GO:0033143 | 32 | 0.054 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.054 | |
| neuron development | GO:0048666 | 113 | 0.053 | Fly |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.053 | |
| oocyte differentiation | GO:0009994 | 2 | 0.053 | |
| rac protein signal transduction | GO:0016601 | 12 | 0.052 | |
| regulation of protein transport | GO:0051223 | 213 | 0.052 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.052 | |
| cellular response to lipid | GO:0071396 | 127 | 0.052 | |
| developmental programmed cell death | GO:0010623 | 3 | 0.052 | |
| canonical wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition | GO:0044334 | 2 | 0.051 | |
| dephosphorylation | GO:0016311 | 209 | 0.051 | |
| regulation of insulin receptor signaling pathway | GO:0046626 | 13 | 0.050 | Fly |
| nitrogen compound transport | GO:0071705 | 191 | 0.050 | |
| sex differentiation | GO:0007548 | 45 | 0.050 | Worm |
| centrosome organization | GO:0051297 | 58 | 0.050 | Fly |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.049 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.048 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.048 | |
| protein export from nucleus | GO:0006611 | 29 | 0.048 | |
| multicellular organism reproduction | GO:0032504 | 42 | 0.048 | Worm |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.047 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.047 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 24 | 0.046 | |
| protein targeting to nucleus | GO:0044744 | 104 | 0.046 | |
| cytokine production | GO:0001816 | 247 | 0.046 | |
| regulation of cellular response to insulin stimulus | GO:1900076 | 17 | 0.046 | Fly |
| nuclear transport | GO:0051169 | 179 | 0.046 | |
| protein import | GO:0017038 | 130 | 0.046 | |
| negative regulation of intracellular transport | GO:0032387 | 60 | 0.046 | |
| regulation of heparan sulfate proteoglycan biosynthetic process | GO:0010908 | 3 | 0.045 | |
| negative regulation of multi organism process | GO:0043901 | 92 | 0.045 | |
| embryonic eye morphogenesis | GO:0048048 | 2 | 0.045 | |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.044 | |
| androgen receptor signaling pathway | GO:0030521 | 34 | 0.043 | |
| oocyte development | GO:0048599 | 1 | 0.041 | |
| negative regulation of cyclin dependent protein serine threonine kinase activity | GO:0045736 | 15 | 0.041 | |
| regulation of neurogenesis | GO:0050767 | 82 | 0.041 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.041 | Yeast Fly |
| vasculature development | GO:0001944 | 181 | 0.041 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 39 | 0.040 | |
| rhythmic behavior | GO:0007622 | 2 | 0.040 | |
| positive regulation of ubiquitin protein transferase activity | GO:0051443 | 18 | 0.040 | |
| growth | GO:0040007 | 202 | 0.040 | Fly |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 52 | 0.039 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.039 | |
| reproductive process | GO:0022414 | 106 | 0.038 | Worm |
| iron ion homeostasis | GO:0055072 | 15 | 0.038 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 4 | 0.038 | |
| dna integrity checkpoint | GO:0031570 | 71 | 0.037 | Fly |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.037 | |
| cyclic nucleotide mediated signaling | GO:0019935 | 26 | 0.037 | |
| acylglycerol biosynthetic process | GO:0046463 | 11 | 0.037 | |
| negative regulation of chromosome organization | GO:2001251 | 48 | 0.037 | |
| stem cell division | GO:0017145 | 2 | 0.036 | |
| negative regulation of g1 s transition of mitotic cell cycle | GO:2000134 | 29 | 0.036 | |
| negative regulation of proteasomal protein catabolic process | GO:1901799 | 32 | 0.036 | |
| cellular response to acid chemical | GO:0071229 | 44 | 0.036 | |
| endocytosis | GO:0006897 | 159 | 0.035 | Worm |
| spermatid differentiation | GO:0048515 | 4 | 0.035 | |
| glycoprotein metabolic process | GO:0009100 | 110 | 0.035 | |
| associative learning | GO:0008306 | 1 | 0.035 | |
| reproduction | GO:0000003 | 63 | 0.035 | Worm |
| protein processing | GO:0016485 | 226 | 0.035 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.034 | |
| regulation of ligase activity | GO:0051340 | 29 | 0.034 | |
| negative regulation of heart induction by canonical wnt signaling pathway | GO:0003136 | 1 | 0.034 | |
| mitotic sister chromatid separation | GO:0051306 | 18 | 0.034 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.033 | |
| pharynx development | GO:0060465 | 1 | 0.033 | |
| transcription factor import into nucleus | GO:0042991 | 40 | 0.033 | |
| positive regulation of proteoglycan biosynthetic process | GO:1902730 | 3 | 0.033 | |
| regulation of epithelial cell proliferation | GO:0050678 | 113 | 0.033 | |
| negative regulation of nucleocytoplasmic transport | GO:0046823 | 37 | 0.033 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.033 | |
| mitotic g1 s transition checkpoint | GO:0044819 | 17 | 0.033 | |
| negative regulation of glial cell differentiation | GO:0045686 | 1 | 0.032 | |
| regulation of cytokine production | GO:0001817 | 232 | 0.032 | |
| neuron projection development | GO:0031175 | 106 | 0.032 | |
| muscle cell proliferation | GO:0033002 | 35 | 0.032 | |
| aging | GO:0007568 | 66 | 0.032 | Worm |
| positive regulation of protein polyubiquitination | GO:1902916 | 3 | 0.032 | |
| immune effector process | GO:0002252 | 159 | 0.032 | |
| neuron death | GO:0070997 | 65 | 0.032 | |
| regulation of protein polymerization | GO:0032271 | 63 | 0.031 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.031 | |
| memory | GO:0007613 | 3 | 0.031 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.031 | |
| regulation of mitotic sister chromatid separation | GO:0010965 | 27 | 0.031 | |
| lipoprotein particle mediated signaling | GO:0055095 | 1 | 0.031 | |
| negative regulation of cell growth | GO:0030308 | 83 | 0.031 | |
| dna repair | GO:0006281 | 198 | 0.031 | |
| maintenance of protein location in cell | GO:0032507 | 56 | 0.031 | |
| regulation of peptide hormone secretion | GO:0090276 | 41 | 0.031 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 48 | 0.030 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.030 | |
| chromatin modification | GO:0016568 | 298 | 0.030 | |
| chromosome segregation | GO:0007059 | 114 | 0.030 | Worm |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.029 | |
| neural tube formation | GO:0001841 | 3 | 0.029 | |
| neuron apoptotic process | GO:0051402 | 39 | 0.029 | |
| regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:2000058 | 7 | 0.029 | |
| neural tube patterning | GO:0021532 | 2 | 0.029 | |
| positive regulation of cellular response to oxidative stress | GO:1900409 | 7 | 0.029 | |
| maintenance of location | GO:0051235 | 112 | 0.029 | |
| negative regulation of cell fate commitment | GO:0010454 | 3 | 0.028 | |
| transmembrane transport | GO:0055085 | 399 | 0.028 | |
| sister chromatid cohesion | GO:0007062 | 24 | 0.028 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.028 | Fly |
| regulation of cell cycle g1 s phase transition | GO:1902806 | 42 | 0.028 | |
| circadian behavior | GO:0048512 | 2 | 0.028 | |
| metanephric nephron epithelium development | GO:0072243 | 4 | 0.028 | |
| meiotic nuclear division | GO:0007126 | 10 | 0.028 | Worm |
| regulation of glycoprotein biosynthetic process | GO:0010559 | 14 | 0.028 | |
| sprouting angiogenesis | GO:0002040 | 29 | 0.028 | |
| monocarboxylic acid metabolic process | GO:0032787 | 185 | 0.028 | |
| regulation of nuclear division | GO:0051783 | 65 | 0.028 | Yeast |
| regulation of g2 m transition of mitotic cell cycle | GO:0010389 | 20 | 0.027 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.027 | Yeast Fly |
| regulation of cell development | GO:0060284 | 161 | 0.027 | |
| centrosome duplication | GO:0051298 | 28 | 0.027 | Fly |
| negative regulation of catagen | GO:0051796 | 1 | 0.027 | |
| response to drug | GO:0042493 | 81 | 0.027 | |
| negative regulation of interleukin 4 production | GO:0032713 | 3 | 0.027 | |
| ectoderm development | GO:0007398 | 3 | 0.027 | |
| circulatory system development | GO:0072359 | 262 | 0.027 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.026 | |
| maintenance of protein location | GO:0045185 | 57 | 0.026 | |
| positive regulation of circadian rhythm | GO:0042753 | 1 | 0.026 | |
| regulation of cell division | GO:0051302 | 116 | 0.026 | Yeast |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.025 | Fly |
| anterior posterior axis specification | GO:0009948 | 2 | 0.025 | |
| peptide hormone secretion | GO:0030072 | 50 | 0.025 | |
| prostate gland development | GO:0030850 | 3 | 0.025 | |
| regulation of epithelial to mesenchymal transition | GO:0010717 | 37 | 0.025 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.024 | |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.024 | |
| hindbrain development | GO:0030902 | 3 | 0.024 | |
| telomere maintenance | GO:0000723 | 32 | 0.024 | |
| regulation of calcium ion transport | GO:0051924 | 79 | 0.024 | |
| negative regulation of transcription factor import into nucleus | GO:0042992 | 17 | 0.024 | |
| response to uv | GO:0009411 | 73 | 0.024 | |
| somitogenesis | GO:0001756 | 2 | 0.024 | |
| male gamete generation | GO:0048232 | 22 | 0.024 | |
| negative regulation of protein catabolic process | GO:0042177 | 59 | 0.023 | |
| nucleus localization | GO:0051647 | 1 | 0.023 | |
| positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902177 | 4 | 0.023 | |
| metal ion transport | GO:0030001 | 272 | 0.023 | |
| protein import into nucleus | GO:0006606 | 104 | 0.023 | |
| glycerolipid metabolic process | GO:0046486 | 107 | 0.023 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.023 | |
| negative regulation of reproductive process | GO:2000242 | 7 | 0.022 | |
| insulin receptor signaling pathway | GO:0008286 | 23 | 0.022 | Fly |
| sensory perception | GO:0007600 | 103 | 0.022 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.022 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.022 | Fly |
| cellular response to inorganic substance | GO:0071241 | 45 | 0.022 | |
| regulation of neuron apoptotic process | GO:0043523 | 35 | 0.022 | |
| positive regulation of intracellular transport | GO:0032388 | 104 | 0.022 | |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.022 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.022 | |
| regulation of chromatin organization | GO:1902275 | 56 | 0.022 | |
| regulation of nephron tubule epithelial cell differentiation | GO:0072182 | 3 | 0.021 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 102 | 0.021 | |
| response to lipid | GO:0033993 | 206 | 0.021 | |
| regulation of growth | GO:0040008 | 165 | 0.021 | Fly |
| glycoprotein biosynthetic process | GO:0009101 | 91 | 0.021 | |
| centriole replication | GO:0007099 | 13 | 0.021 | |
| cation homeostasis | GO:0055080 | 189 | 0.021 | Yeast |
| cardiac muscle cell contraction | GO:0086003 | 4 | 0.021 | |
| cardiac muscle cell cardiac muscle cell adhesion | GO:0086042 | 1 | 0.021 | |
| negative regulation of nf kappab import into nucleus | GO:0042347 | 12 | 0.021 | |
| response to inorganic substance | GO:0010035 | 127 | 0.021 | |
| spermatogenesis | GO:0007283 | 22 | 0.021 | |
| insulin secretion | GO:0030073 | 39 | 0.020 | |
| immune system development | GO:0002520 | 195 | 0.020 | |
| regulation of organ formation | GO:0003156 | 4 | 0.020 | |
| regulation of metanephros development | GO:0072215 | 4 | 0.020 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.020 | Worm |
| response to acid chemical | GO:0001101 | 66 | 0.020 | |
| regulation of cell cycle g2 m phase transition | GO:1902749 | 22 | 0.020 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.020 | |
| positive regulation of metaphase anaphase transition of cell cycle | GO:1902101 | 6 | 0.020 | |
| single organism nuclear import | GO:1902593 | 104 | 0.020 | |
| glycerolipid biosynthetic process | GO:0045017 | 51 | 0.020 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 57 | 0.019 | |
| regulation of mitotic metaphase anaphase transition | GO:0030071 | 26 | 0.019 | |
| establishment of endothelial blood brain barrier | GO:0014045 | 1 | 0.019 | |
| canonical wnt signaling pathway involved in regulation of cell proliferation | GO:0044340 | 2 | 0.019 | |
| spermatid development | GO:0007286 | 4 | 0.019 | |
| protein dephosphorylation | GO:0006470 | 81 | 0.019 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 19 | 0.019 | |
| regulation of cardioblast differentiation | GO:0051890 | 4 | 0.019 | |
| regulation of determination of dorsal identity | GO:2000015 | 2 | 0.019 | |
| regulation of nervous system development | GO:0051960 | 88 | 0.018 | Fly |
| sensory perception of sound | GO:0007605 | 37 | 0.018 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.018 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.018 | |
| cellular response to organic cyclic compound | GO:0071407 | 127 | 0.018 | |
| cognition | GO:0050890 | 43 | 0.018 | |
| organelle localization | GO:0051640 | 84 | 0.018 | Worm |
| regulation of secretion | GO:0051046 | 194 | 0.018 | |
| cell growth | GO:0016049 | 160 | 0.018 | |
| negative regulation of cellular response to insulin stimulus | GO:1900077 | 8 | 0.018 | Fly |
| chromosome separation | GO:0051304 | 23 | 0.018 | |
| protein autoubiquitination | GO:0051865 | 37 | 0.018 | |
| regulation of leukocyte differentiation | GO:1902105 | 61 | 0.018 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.018 | |
| protein acetylation | GO:0006473 | 116 | 0.017 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.017 | |
