IMP: Integrative Multi-species Prediction

Homo sapiens

82 known processes

SLC25A5

solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5

(Aliases: AAC2,2F1,T2,T3,ANT2)

Entrez: 292
HPRD: 02147
Ensembl: ENSG00000005022
HGNC: 10991
MIM: 300150
UniProtKB: Q6NVC0
UniProtKB: P05141

Process Predictions
Disease Predictions

SLC25A5 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
oxidation reduction process	GO:0055114	396	0.915	Yeast
post embryonic development	GO:0009791	2	0.891	Worm
nucleoside phosphate biosynthetic process	GO:1901293	109	0.838	Fly
purine ribonucleoside metabolic process	GO:0046128	437	0.817	Fly
organonitrogen compound biosynthetic process	GO:1901566	200	0.816	Yeast Fly
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.798	Fly
generation of precursor metabolites and energy	GO:0006091	68	0.794	Yeast
purine nucleoside monophosphate metabolic process	GO:0009126	186	0.766	Fly
ribonucleotide biosynthetic process	GO:0009260	81	0.717	Fly
nucleoside monophosphate metabolic process	GO:0009123	191	0.684	Fly
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.667	Fly
nucleotide biosynthetic process	GO:0009165	109	0.626	Fly
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.607	Fly
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.596	Fly
membrane organization	GO:0061024	292	0.581
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.578	Fly
determination of adult lifespan	GO:0008340	2	0.556	Worm Fly
atp metabolic process	GO:0046034	176	0.512	Fly
ribose phosphate biosynthetic process	GO:0046390	82	0.505	Fly
carbohydrate derivative biosynthetic process	GO:1901137	207	0.505	Fly
anion transport	GO:0006820	161	0.433	Yeast Fly
nucleoside triphosphate metabolic process	GO:0009141	422	0.391	Fly
multicellular organismal aging	GO:0010259	3	0.388	Worm Fly
transmembrane transport	GO:0055085	399	0.367	Yeast Fly
energy derivation by oxidation of organic compounds	GO:0015980	43	0.332	Yeast
hemopoiesis	GO:0030097	180	0.328
cellular respiration	GO:0045333	21	0.303	Yeast
mitochondrial membrane organization	GO:0007006	40	0.295
inorganic cation transmembrane transport	GO:0098662	194	0.289
organelle assembly	GO:0070925	176	0.279
cation transport	GO:0006812	331	0.275
purine containing compound biosynthetic process	GO:0072522	88	0.263	Fly
cofactor metabolic process	GO:0051186	87	0.257	Yeast
inorganic ion transmembrane transport	GO:0098660	231	0.250
vesicle mediated transport	GO:0016192	371	0.249	Worm Fly
organophosphate biosynthetic process	GO:0090407	163	0.237	Fly
cation transmembrane transport	GO:0098655	238	0.226
cation homeostasis	GO:0055080	189	0.218	Fly
ion homeostasis	GO:0050801	230	0.215	Fly
ion transmembrane transport	GO:0034220	338	0.204	Yeast Fly
immune system development	GO:0002520	195	0.198
ossification	GO:0001503	121	0.186
ribonucleotide catabolic process	GO:0009261	405	0.182
negative regulation of cell proliferation	GO:0008285	228	0.182
energy coupled proton transport down electrochemical gradient	GO:0015985	2	0.173
mating	GO:0007618	1	0.170
embryo development	GO:0009790	123	0.166	Worm
organophosphate catabolic process	GO:0046434	430	0.161
nucleotide catabolic process	GO:0009166	408	0.156
purine nucleotide catabolic process	GO:0006195	405	0.151
monovalent inorganic cation transport	GO:0015672	128	0.149
cytoplasmic transport	GO:0016482	379	0.145
nucleoside triphosphate catabolic process	GO:0009143	394	0.143
positive regulation of apoptotic process	GO:0043065	246	0.141	Worm
purine ribonucleoside catabolic process	GO:0046130	398	0.140
purine ribonucleotide biosynthetic process	GO:0009152	79	0.140	Fly
positive regulation of developmental process	GO:0051094	314	0.138
hematopoietic or lymphoid organ development	GO:0048534	186	0.129
chemical homeostasis	GO:0048878	306	0.126	Fly
negative regulation of apoptotic process	GO:0043066	316	0.122
regulation of mitochondrial membrane permeability involved in apoptotic process	GO:1902108	18	0.121
negative regulation of programmed cell death	GO:0043069	321	0.118
oogenesis	GO:0048477	2	0.113
nitrogen compound transport	GO:0071705	191	0.113	Yeast Fly
purine nucleotide biosynthetic process	GO:0006164	84	0.112	Fly
endocytosis	GO:0006897	159	0.105	Worm
purine nucleoside catabolic process	GO:0006152	398	0.102
purine ribonucleoside biosynthetic process	GO:0046129	23	0.102	Fly
glycosyl compound biosynthetic process	GO:1901659	27	0.100	Fly
purine nucleoside monophosphate catabolic process	GO:0009128	158	0.098
aging	GO:0007568	66	0.094	Worm Fly
inorganic anion transmembrane transport	GO:0098661	47	0.093
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	69	0.087
protein oligomerization	GO:0051259	173	0.087
purine containing compound catabolic process	GO:0072523	411	0.086
cellular response to cytokine stimulus	GO:0071345	181	0.086
purine nucleoside biosynthetic process	GO:0042451	23	0.085	Fly
regulation of cell differentiation	GO:0045595	393	0.084
nucleoside phosphate catabolic process	GO:1901292	412	0.083
cellular chemical homeostasis	GO:0055082	180	0.082	Fly
secretion by cell	GO:0032940	226	0.080
cellular metal ion homeostasis	GO:0006875	146	0.080	Fly
glycosyl compound catabolic process	GO:1901658	413	0.080
nucleoside triphosphate biosynthetic process	GO:0009142	20	0.080	Fly
secretion	GO:0046903	254	0.079
purine nucleoside monophosphate biosynthetic process	GO:0009127	16	0.077	Fly
cellular homeostasis	GO:0019725	196	0.077	Fly
nucleoside catabolic process	GO:0009164	408	0.074
osteoblast differentiation	GO:0001649	92	0.074
regulation of purine nucleotide metabolic process	GO:1900542	264	0.074	Fly
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.073
atp synthesis coupled electron transport	GO:0042773	4	0.068
maintenance of location	GO:0051235	112	0.065
positive regulation of hydrolase activity	GO:0051345	331	0.065
epithelial cell differentiation	GO:0030855	141	0.063
positive regulation of immune system process	GO:0002684	283	0.063
oxidative phosphorylation	GO:0006119	10	0.063
mitochondrion organization	GO:0007005	156	0.061
purine ribonucleoside monophosphate biosynthetic process	GO:0009168	16	0.060	Fly
cell differentiation in spinal cord	GO:0021515	1	0.060
regulation of peptidase activity	GO:0052547	180	0.059
lipid catabolic process	GO:0016042	84	0.057
regulation of endopeptidase activity	GO:0052548	170	0.057
regulation of nucleotide metabolic process	GO:0006140	269	0.056	Fly
atp synthesis coupled proton transport	GO:0015986	2	0.056
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.054
nucleoside diphosphate metabolic process	GO:0009132	16	0.054
negative regulation of apoptotic signaling pathway	GO:2001234	97	0.053
nucleoside monophosphate catabolic process	GO:0009125	159	0.052
phosphate ion transport	GO:0006817	7	0.052
system process	GO:0003008	349	0.052
immune response	GO:0006955	307	0.051
female gamete generation	GO:0007292	2	0.050
microtubule cytoskeleton organization	GO:0000226	176	0.050
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.050
amine metabolic process	GO:0009308	44	0.048
innate immune response	GO:0045087	178	0.048
protein localization to organelle	GO:0033365	280	0.048
purine ribonucleoside triphosphate biosynthetic process	GO:0009206	11	0.047	Fly
ribonucleoside monophosphate catabolic process	GO:0009158	158	0.047
negative regulation of cell death	GO:0060548	345	0.047
spermatid differentiation	GO:0048515	4	0.047
single organism cellular localization	GO:1902580	332	0.046
lipid localization	GO:0010876	106	0.046
positive regulation of proteolysis	GO:0045862	142	0.046
purine ribonucleotide catabolic process	GO:0009154	404	0.045
cellular ion homeostasis	GO:0006873	168	0.045	Fly
spermatid development	GO:0007286	4	0.045
regulation of nucleoside metabolic process	GO:0009118	209	0.044	Fly
response to hormone	GO:0009725	175	0.044
lipid metabolic process	GO:0006629	381	0.043
regulation of proteolysis	GO:0030162	293	0.043
regulation of feeding behavior	GO:0060259	3	0.043
negative regulation of cellular component organization	GO:0051129	235	0.041
nucleoside biosynthetic process	GO:0009163	26	0.041	Fly
positive regulation of nucleotide metabolic process	GO:0045981	230	0.041	Fly
mitochondrial transport	GO:0006839	60	0.040
purine nucleoside triphosphate biosynthetic process	GO:0009145	11	0.040	Fly
regulation of transferase activity	GO:0051338	355	0.039
negative regulation of phosphate metabolic process	GO:0045936	267	0.039
phosphate ion transmembrane transport	GO:0035435	4	0.039
regulation of epithelial cell proliferation	GO:0050678	113	0.039
response to hypoxia	GO:0001666	96	0.038
excretion	GO:0007588	9	0.037
defense response	GO:0006952	315	0.037
single organism membrane organization	GO:0044802	268	0.037
inorganic anion transport	GO:0015698	60	0.037
negative regulation of multicellular organismal process	GO:0051241	317	0.036
regeneration	GO:0031099	4	0.036
ribonucleoside catabolic process	GO:0042454	406	0.035
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	281	0.035
response to other organism	GO:0051707	261	0.034
purine ribonucleoside monophosphate catabolic process	GO:0009169	158	0.033
intracellular protein transport	GO:0006886	270	0.032
hydrogen transport	GO:0006818	23	0.032
reproduction	GO:0000003	63	0.032	Worm
establishment of protein localization to organelle	GO:0072594	172	0.031
cellular macromolecular complex assembly	GO:0034622	324	0.030
negative regulation of transport	GO:0051051	176	0.030
ribonucleoside monophosphate biosynthetic process	GO:0009156	17	0.029	Fly
response to cytokine	GO:0034097	232	0.029
activation of cysteine type endopeptidase activity involved in apoptotic process	GO:0006919	49	0.029
metal ion transport	GO:0030001	272	0.029
mrna metabolic process	GO:0016071	175	0.028
regulation of immune response	GO:0050776	201	0.028
cellular lipid metabolic process	GO:0044255	303	0.028
anion transmembrane transport	GO:0098656	76	0.028
embryo development ending in birth or egg hatching	GO:0009792	34	0.027	Worm
negative regulation of immune system process	GO:0002683	136	0.027
protein processing	GO:0016485	226	0.027
central nervous system development	GO:0007417	123	0.026
regulation of defense response	GO:0031347	154	0.026
response to external biotic stimulus	GO:0043207	261	0.025
positive regulation of cell death	GO:0010942	263	0.025	Worm
regulation of cell adhesion	GO:0030155	166	0.025
protein tetramerization	GO:0051262	47	0.024
positive regulation of programmed cell death	GO:0043068	249	0.024	Worm
negative regulation of cell differentiation	GO:0045596	171	0.024
response to wounding	GO:0009611	168	0.024
receptor mediated endocytosis	GO:0006898	84	0.023	Worm
protein import	GO:0017038	130	0.023
negative regulation of catalytic activity	GO:0043086	335	0.023
positive regulation of purine nucleotide metabolic process	GO:1900544	227	0.023	Fly
ribonucleoside biosynthetic process	GO:0042455	25	0.023	Fly
microtubule based process	GO:0007017	210	0.022
cellular amine metabolic process	GO:0044106	41	0.022
gtp metabolic process	GO:0046039	239	0.022
cellular component morphogenesis	GO:0032989	314	0.022
protein targeting	GO:0006605	187	0.021
tissue homeostasis	GO:0001894	63	0.021
regulation of kinase activity	GO:0043549	314	0.021
cell growth	GO:0016049	160	0.021
sulfur compound metabolic process	GO:0006790	101	0.021
i kappab kinase nf kappab signaling	GO:0007249	166	0.021
neuron differentiation	GO:0030182	138	0.020
negative regulation of phosphorus metabolic process	GO:0010563	267	0.020
wound healing	GO:0042060	115	0.020
cell development	GO:0048468	328	0.020
generation of neurons	GO:0048699	152	0.020
ribonucleoside triphosphate biosynthetic process	GO:0009201	12	0.020	Fly
myeloid cell differentiation	GO:0030099	117	0.019
reactive oxygen species metabolic process	GO:0072593	75	0.019
apoptotic signaling pathway	GO:0097190	268	0.019
regulation of oxidative phosphorylation	GO:0002082	3	0.019
positive regulation of endopeptidase activity	GO:0010950	84	0.018
organic anion transport	GO:0015711	103	0.018	Yeast Fly
guanosine containing compound metabolic process	GO:1901068	244	0.018
carbohydrate metabolic process	GO:0005975	207	0.018
cell substrate adhesion	GO:0031589	132	0.018
cellular response to lipid	GO:0071396	127	0.018
intracellular receptor signaling pathway	GO:0030522	104	0.018
regulation of mitochondrial membrane permeability	GO:0046902	25	0.018
negative regulation of cell growth	GO:0030308	83	0.018
transition metal ion transport	GO:0000041	23	0.018
calcium ion homeostasis	GO:0055074	122	0.018	Fly
regulation of cellular amine metabolic process	GO:0033238	11	0.018
nervous system development	GO:0007399	293	0.017	Fly
negative regulation of defense response	GO:0031348	47	0.017
cell adhesion	GO:0007155	325	0.017
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.017
negative regulation of neural precursor cell proliferation	GO:2000178	1	0.017
negative regulation of protein phosphatase type 2b activity	GO:0032513	2	0.017
regulation of cell development	GO:0060284	161	0.017
positive regulation of transport	GO:0051050	336	0.017
striated muscle myosin thick filament assembly	GO:0071688	2	0.017
cellular component disassembly	GO:0022411	92	0.017
regulation of protein localization	GO:0032880	296	0.017
cellular cation homeostasis	GO:0030003	163	0.017	Fly
metal ion homeostasis	GO:0055065	169	0.017	Fly
response to oxygen levels	GO:0070482	100	0.016
alcohol metabolic process	GO:0006066	114	0.016
tissue regeneration	GO:0042246	3	0.016
epithelium development	GO:0060429	227	0.016
positive regulation of catabolic process	GO:0009896	310	0.016
regulation of myeloid cell differentiation	GO:0045637	81	0.016
positive regulation of cell proliferation	GO:0008284	301	0.016
cellular amino acid metabolic process	GO:0006520	116	0.016
positive regulation of peptidase activity	GO:0010952	88	0.016
programmed necrotic cell death	GO:0097300	18	0.016	Human
tissue morphogenesis	GO:0048729	96	0.016
regulation of membrane potential	GO:0042391	95	0.016	Fly
brain development	GO:0007420	97	0.015
cellular response to oxygen containing compound	GO:1901701	276	0.015
protein maturation	GO:0051604	233	0.015
positive regulation of cell differentiation	GO:0045597	211	0.015
biological adhesion	GO:0022610	331	0.015
regulation of membrane permeability	GO:0090559	25	0.015
activation of immune response	GO:0002253	114	0.015
small molecule biosynthetic process	GO:0044283	157	0.015
guanosine containing compound catabolic process	GO:1901069	239	0.014
lymphocyte activation	GO:0046649	133	0.014
positive regulation of cysteine type endopeptidase activity	GO:2001056	79	0.014
response to lipid	GO:0033993	206	0.014
response to abiotic stimulus	GO:0009628	336	0.014	Fly
cofactor transport	GO:0051181	11	0.014	Yeast
regulation of growth	GO:0040008	165	0.014
positive regulation of immune response	GO:0050778	159	0.014
multi organism cellular process	GO:0044764	156	0.014
cellular modified amino acid metabolic process	GO:0006575	64	0.014
regulation of cellular component movement	GO:0051270	334	0.014
protein secretion	GO:0009306	98	0.013
epithelial cell proliferation	GO:0050673	128	0.013
spinal cord development	GO:0021510	4	0.013
regulation of establishment of protein localization	GO:0070201	242	0.013
neurogenesis	GO:0022008	169	0.013
mrna processing	GO:0006397	133	0.013
body morphogenesis	GO:0010171	11	0.013	Worm
response to steroid hormone	GO:0048545	80	0.013
development of primary sexual characteristics	GO:0045137	35	0.013	Worm
spindle elongation	GO:0051231	4	0.013
positive regulation of cellular component organization	GO:0051130	376	0.013
establishment of protein localization to membrane	GO:0090150	121	0.013
cellular ketone metabolic process	GO:0042180	80	0.013
cell part morphogenesis	GO:0032990	137	0.013
regulation of anatomical structure morphogenesis	GO:0022603	286	0.013
actin filament based process	GO:0030029	224	0.013
single organism cell adhesion	GO:0098602	179	0.013
regulation of i kappab kinase nf kappab signaling	GO:0043122	162	0.012
regulation of cellular component biogenesis	GO:0044087	281	0.012
rna catabolic process	GO:0006401	71	0.012
protein localization to membrane	GO:0072657	160	0.012
atp biosynthetic process	GO:0006754	11	0.012	Fly
phagocytosis	GO:0006909	42	0.012
growth	GO:0040007	202	0.012	Fly
atp catabolic process	GO:0006200	157	0.012
multi organism reproductive process	GO:0044703	54	0.012
ribonucleoprotein complex subunit organization	GO:0071826	81	0.012
cellular macromolecule catabolic process	GO:0044265	380	0.012
regulation of innate immune response	GO:0045088	97	0.012
regulation of neurogenesis	GO:0050767	82	0.012
electron transport chain	GO:0022900	8	0.012
ribonucleoprotein complex biogenesis	GO:0022613	116	0.012
type b pancreatic cell development	GO:0003323	4	0.012
regulation of mitochondrial membrane potential	GO:0051881	23	0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	116	0.012
glycerolipid metabolic process	GO:0046486	107	0.012
regulation of multi organism process	GO:0043900	157	0.011
negative regulation of hydrolase activity	GO:0051346	182	0.011
regulation of intracellular transport	GO:0032386	195	0.011
immune effector process	GO:0002252	159	0.011
negative regulation of cellular protein metabolic process	GO:0032269	353	0.011
glycerophospholipid metabolic process	GO:0006650	84	0.011
positive regulation of cellular amine metabolic process	GO:0033240	7	0.011
cellular divalent inorganic cation homeostasis	GO:0072503	128	0.011	Fly
neuroblast proliferation	GO:0007405	4	0.011
response to biotic stimulus	GO:0009607	276	0.011
regulation of secretion	GO:0051046	194	0.011
negative regulation of cell adhesion	GO:0007162	64	0.011
cellular amide metabolic process	GO:0043603	69	0.011
regulation of nucleotide catabolic process	GO:0030811	205	0.011
nuclear transcribed mrna catabolic process	GO:0000956	48	0.011
positive regulation of translation	GO:0045727	35	0.011
nuclear transport	GO:0051169	179	0.011
response to drug	GO:0042493	81	0.011
multicellular organism reproduction	GO:0032504	42	0.011
angiogenesis	GO:0001525	147	0.011
regulation of mitochondrion organization	GO:0010821	54	0.011
cytokine production	GO:0001816	247	0.010
regulation of protein transport	GO:0051223	213	0.010
posttranscriptional regulation of gene expression	GO:0010608	213	0.010
dna catabolic process	GO:0006308	49	0.010
ventral spinal cord development	GO:0021517	1	0.010
nucleocytoplasmic transport	GO:0006913	176	0.010
rna processing	GO:0006396	255	0.010
regulation of sequence specific dna binding transcription factor activity	GO:0051090	211	0.010

SLC25A5 disease predictions

Disease	DO term ID	Size	Probability
organ system cancer	DOID:0050686	164	0.189
cancer	DOID:162	167	0.189
disease of cellular proliferation	DOID:14566	174	0.189
immune system disease	DOID:2914	155	0.025
inherited metabolic disorder	DOID:655	242	0.022
disease of metabolism	DOID:0014667	295	0.022
nervous system disease	DOID:863	431	0.013
central nervous system disease	DOID:331	186	0.013
gastrointestinal system cancer	DOID:3119	52	0.011

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