| endoplasmic reticulum unfolded protein response | GO:0030968 | 16 | 1.000 | Fly |
| cellular response to topologically incorrect protein | GO:0035967 | 19 | 0.999 | Fly |
| response to unfolded protein | GO:0006986 | 24 | 0.999 | Fly |
| er nucleus signaling pathway | GO:0006984 | 23 | 0.998 | Fly |
| cellular response to unfolded protein | GO:0034620 | 16 | 0.998 | Fly |
| response to topologically incorrect protein | GO:0035966 | 29 | 0.996 | Fly |
| protein ubiquitination | GO:0016567 | 314 | 0.995 | Human Fly |
| response to endoplasmic reticulum stress | GO:0034976 | 49 | 0.995 | Mouse Fly |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.992 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.991 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.988 | Human Fly |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.977 | Mouse |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.957 | |
| regulation of nuclease activity | GO:0032069 | 11 | 0.928 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.916 | |
| activation of signaling protein activity involved in unfolded protein response | GO:0006987 | 3 | 0.907 | |
| intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | GO:0070059 | 12 | 0.907 | Mouse |
| cellular protein catabolic process | GO:0044257 | 261 | 0.902 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.882 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 31 | 0.854 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.824 | |
| rrna metabolic process | GO:0016072 | 40 | 0.799 | |
| protein catabolic process | GO:0030163 | 325 | 0.761 | |
| protein oligomerization | GO:0051259 | 173 | 0.754 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.747 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.702 | Human |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.702 | |
| cell cycle arrest | GO:0007050 | 71 | 0.690 | |
| rna catabolic process | GO:0006401 | 71 | 0.611 | |
| protein homooligomerization | GO:0051260 | 100 | 0.594 | |
| dna packaging | GO:0006323 | 77 | 0.552 | |
| membrane organization | GO:0061024 | 292 | 0.527 | |
| protein deubiquitination | GO:0016579 | 79 | 0.526 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.518 | |
| positive regulation of nuclease activity | GO:0032075 | 5 | 0.499 | |
| alcohol metabolic process | GO:0006066 | 114 | 0.495 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.487 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.473 | |
| execution phase of apoptosis | GO:0097194 | 32 | 0.451 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.437 | Human |
| cellular component disassembly | GO:0022411 | 92 | 0.436 | |
| dna conformation change | GO:0071103 | 113 | 0.433 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.422 | |
| ncrna catabolic process | GO:0034661 | 14 | 0.419 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.381 | |
| mrna metabolic process | GO:0016071 | 175 | 0.378 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 102 | 0.354 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.351 | Human |
| histone modification | GO:0016570 | 251 | 0.337 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.330 | Mouse |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.293 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 71 | 0.275 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.265 | |
| chromosome segregation | GO:0007059 | 114 | 0.263 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.229 | |
| dna repair | GO:0006281 | 198 | 0.226 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.222 | Human |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.218 | Mouse |
| protein modification by small protein removal | GO:0070646 | 92 | 0.216 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.210 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.206 | |
| rna splicing | GO:0008380 | 131 | 0.204 | |
| apoptotic nuclear changes | GO:0030262 | 13 | 0.196 | |
| single organism membrane organization | GO:0044802 | 268 | 0.192 | |
| regulation of endoplasmic reticulum unfolded protein response | GO:1900101 | 5 | 0.192 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.191 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.183 | |
| chromatin organization | GO:0006325 | 351 | 0.183 | |
| cellular component disassembly involved in execution phase of apoptosis | GO:0006921 | 13 | 0.181 | |
| chromatin modification | GO:0016568 | 298 | 0.178 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.176 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 87 | 0.172 | |
| regulation of ligase activity | GO:0051340 | 29 | 0.169 | |
| ncrna metabolic process | GO:0034660 | 108 | 0.163 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.157 | |
| mitotic nuclear division | GO:0007067 | 119 | 0.150 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.149 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.148 | Mouse |
| endomembrane system organization | GO:0010256 | 196 | 0.148 | |
| organelle fission | GO:0048285 | 149 | 0.148 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.146 | |
| protein maturation | GO:0051604 | 233 | 0.142 | Human |
| response to radiation | GO:0009314 | 151 | 0.141 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.139 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.138 | Mouse |
| positive regulation of endoplasmic reticulum unfolded protein response | GO:1900103 | 4 | 0.138 | |
| microtubule based process | GO:0007017 | 210 | 0.138 | |
| cellular response to misfolded protein | GO:0071218 | 2 | 0.137 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.135 | |
| protein acylation | GO:0043543 | 138 | 0.132 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.130 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.127 | |
| amine metabolic process | GO:0009308 | 44 | 0.124 | |
| cation transport | GO:0006812 | 331 | 0.114 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.114 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.110 | |
| cell development | GO:0048468 | 328 | 0.105 | |
| inositol metabolic process | GO:0006020 | 3 | 0.103 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.103 | Mouse |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.101 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.101 | Mouse |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 37 | 0.101 | |
| rna splicing via endonucleolytic cleavage and ligation | GO:0000394 | 8 | 0.100 | |
| regulation of potassium ion transmembrane transport | GO:1901379 | 20 | 0.098 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.095 | |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 61 | 0.095 | |
| histone acetylation | GO:0016573 | 93 | 0.094 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.093 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.092 | |
| regulation of metal ion transport | GO:0010959 | 120 | 0.092 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.091 | Human |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.091 | |
| positive regulation of protein ubiquitination | GO:0031398 | 53 | 0.091 | |
| chromosome condensation | GO:0030261 | 15 | 0.090 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.089 | |
| regulation of rna splicing | GO:0043484 | 62 | 0.089 | |
| post embryonic development | GO:0009791 | 2 | 0.089 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.088 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.086 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.085 | |
| transmembrane transport | GO:0055085 | 399 | 0.080 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.080 | |
| positive regulation of proteasomal protein catabolic process | GO:1901800 | 35 | 0.077 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.077 | |
| oocyte differentiation | GO:0009994 | 2 | 0.077 | |
| positive regulation of mesenchymal stem cell differentiation | GO:2000741 | 4 | 0.077 | |
| regulation of binding | GO:0051098 | 111 | 0.077 | |
| golgi organization | GO:0007030 | 38 | 0.076 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.076 | |
| regulation of ion transmembrane transport | GO:0034765 | 132 | 0.075 | |
| mitotic sister chromatid segregation | GO:0000070 | 53 | 0.074 | |
| regulation of transmembrane transport | GO:0034762 | 139 | 0.074 | |
| protein monoubiquitination | GO:0006513 | 39 | 0.073 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.072 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.069 | |
| positive regulation of calcium ion transport | GO:0051928 | 51 | 0.068 | |
| rrna catabolic process | GO:0016075 | 6 | 0.068 | |
| developmental programmed cell death | GO:0010623 | 3 | 0.066 | |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.066 | |
| regulation of mitosis | GO:0007088 | 63 | 0.065 | |
| regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:2000058 | 7 | 0.064 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.064 | |
| maintenance of location | GO:0051235 | 112 | 0.063 | |
| negative regulation of chromosome organization | GO:2001251 | 48 | 0.063 | |
| regulation of transmembrane transporter activity | GO:0022898 | 74 | 0.062 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.061 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 35 | 0.060 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.060 | |
| response to ionizing radiation | GO:0010212 | 65 | 0.060 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.060 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.059 | |
| regulation of cellular component size | GO:0032535 | 82 | 0.058 | |
| embryonic camera type eye development | GO:0031076 | 2 | 0.057 | |
| retrograde protein transport er to cytosol | GO:0030970 | 5 | 0.056 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.056 | |
| rna processing | GO:0006396 | 255 | 0.055 | |
| positive regulation of axon extension | GO:0045773 | 4 | 0.055 | |
| negative regulation of intrinsic apoptotic signaling pathway | GO:2001243 | 40 | 0.055 | Mouse |
| negative regulation of proteasomal protein catabolic process | GO:1901799 | 32 | 0.054 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.054 | |
| cell activation | GO:0001775 | 213 | 0.053 | |
| response to growth factor | GO:0070848 | 205 | 0.052 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.052 | |
| maintenance of protein location | GO:0045185 | 57 | 0.051 | |
| maintenance of location in cell | GO:0051651 | 62 | 0.051 | |
| establishment of protein localization to membrane | GO:0090150 | 121 | 0.051 | |
| trabecula morphogenesis | GO:0061383 | 2 | 0.050 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.049 | |
| nuclear division | GO:0000280 | 128 | 0.048 | |
| histone h4 k12 acetylation | GO:0043983 | 6 | 0.048 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.048 | Human |
| regulation of protein stability | GO:0031647 | 87 | 0.048 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.048 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.047 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.047 | |
| positive regulation of locomotion | GO:0040017 | 186 | 0.046 | |
| histone h3 acetylation | GO:0043966 | 45 | 0.044 | |
| double strand break repair | GO:0006302 | 101 | 0.044 | |
| divalent inorganic cation transport | GO:0072511 | 158 | 0.044 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.044 | |
| regulation of ion transport | GO:0043269 | 189 | 0.044 | |
| intracellular protein transport | GO:0006886 | 270 | 0.043 | |
| regulation of calcium ion transport | GO:0051924 | 79 | 0.043 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.043 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.043 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.042 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.042 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.041 | |
| maintenance of protein localization in organelle | GO:0072595 | 15 | 0.041 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.040 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.040 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.040 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 158 | 0.040 | |
| atp catabolic process | GO:0006200 | 157 | 0.040 | |
| regulation of protein localization | GO:0032880 | 296 | 0.039 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.039 | |
| protein processing | GO:0016485 | 226 | 0.039 | Human |
| regulation of histone modification | GO:0031056 | 47 | 0.039 | |
| embryonic camera type eye morphogenesis | GO:0048596 | 2 | 0.039 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 38 | 0.038 | |
| positive regulation of transport | GO:0051050 | 336 | 0.038 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.038 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 94 | 0.038 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.038 | |
| regulation of developmental growth | GO:0048638 | 30 | 0.037 | |
| protein autoubiquitination | GO:0051865 | 37 | 0.037 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.037 | |
| cellular response to hypoxia | GO:0071456 | 51 | 0.037 | |
| regulation of protein processing | GO:0070613 | 150 | 0.037 | Human |
| dna damage response signal transduction resulting in transcription | GO:0042772 | 12 | 0.037 | |
| locomotory behavior | GO:0007626 | 1 | 0.036 | |
| chemical homeostasis | GO:0048878 | 306 | 0.036 | |
| protein localization to organelle | GO:0033365 | 280 | 0.036 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.036 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.036 | |
| response to toxic substance | GO:0009636 | 37 | 0.036 | |
| oocyte development | GO:0048599 | 1 | 0.036 | |
| establishment of monopolar cell polarity | GO:0061162 | 1 | 0.036 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.036 | |
| rna phosphodiester bond hydrolysis endonucleolytic | GO:0090502 | 15 | 0.036 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 158 | 0.036 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.035 | |
| regulation of mitotic metaphase anaphase transition | GO:0030071 | 26 | 0.035 | |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.035 | |
| negative regulation of protein ubiquitination | GO:0031397 | 35 | 0.035 | |
| metal ion transport | GO:0030001 | 272 | 0.035 | |
| peptidyl lysine acetylation | GO:0018394 | 101 | 0.034 | |
| regulation of locomotion | GO:0040012 | 329 | 0.034 | |
| oogenesis | GO:0048477 | 2 | 0.034 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.034 | Mouse |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 30 | 0.034 | |
| cell migration involved in gastrulation | GO:0042074 | 1 | 0.033 | |
| monovalent inorganic cation transport | GO:0015672 | 128 | 0.033 | |
| regulation of hormone levels | GO:0010817 | 125 | 0.033 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.033 | |
| negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:2000059 | 3 | 0.033 | |
| regulation of actin filament based process | GO:0032970 | 141 | 0.033 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.032 | |
| negative regulation of protein catabolic process | GO:0042177 | 59 | 0.032 | |
| regulation of protein polymerization | GO:0032271 | 63 | 0.032 | |
| regulation of gene expression epigenetic | GO:0040029 | 73 | 0.032 | |
| hindbrain development | GO:0030902 | 3 | 0.032 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.032 | |
| regulation of stem cell differentiation | GO:2000736 | 56 | 0.032 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.032 | |
| nucleus organization | GO:0006997 | 28 | 0.031 | |
| response to light stimulus | GO:0009416 | 87 | 0.031 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.031 | |
| sister chromatid segregation | GO:0000819 | 54 | 0.031 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.031 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.031 | |
| positive regulation of protein binding | GO:0032092 | 24 | 0.031 | |
| organelle localization | GO:0051640 | 84 | 0.031 | |
| regulation of chromosome organization | GO:0033044 | 103 | 0.031 | |
| internal peptidyl lysine acetylation | GO:0018393 | 97 | 0.030 | |
| compound eye development | GO:0048749 | 1 | 0.030 | |
| chemotaxis | GO:0006935 | 157 | 0.030 | |
| heart morphogenesis | GO:0003007 | 48 | 0.030 | |
| inner ear morphogenesis | GO:0042472 | 4 | 0.030 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.030 | |
| chromosome separation | GO:0051304 | 23 | 0.029 | |
| positive regulation of response to external stimulus | GO:0032103 | 88 | 0.029 | |
| glycoprotein biosynthetic process | GO:0009101 | 91 | 0.029 | |
| hypothalamus development | GO:0021854 | 1 | 0.029 | |
| protein acetylation | GO:0006473 | 116 | 0.029 | |
| peptidyl lysine modification | GO:0018205 | 144 | 0.028 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 50 | 0.028 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.028 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.028 | |
| defense response | GO:0006952 | 315 | 0.028 | |
| toxin transport | GO:1901998 | 4 | 0.027 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.027 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.027 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 37 | 0.027 | |
| regulation of synaptic plasticity | GO:0048167 | 3 | 0.027 | |
| positive regulation of growth | GO:0045927 | 58 | 0.027 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 72 | 0.027 | |
| store operated calcium entry | GO:0002115 | 3 | 0.026 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.026 | |
| establishment of organelle localization | GO:0051656 | 59 | 0.026 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.026 | Mouse |
| signal transduction by p53 class mediator | GO:0072331 | 72 | 0.026 | |
| spinal cord development | GO:0021510 | 4 | 0.026 | |
| maintenance of protein location in cell | GO:0032507 | 56 | 0.026 | |
| atp metabolic process | GO:0046034 | 176 | 0.026 | |
| regulation of chromatin modification | GO:1903308 | 51 | 0.026 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 44 | 0.026 | |
| regulation of cell division | GO:0051302 | 116 | 0.026 | |
| actin filament based process | GO:0030029 | 224 | 0.026 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 37 | 0.025 | |
| regulation of growth | GO:0040008 | 165 | 0.025 | |
| signal transduction in response to dna damage | GO:0042770 | 57 | 0.025 | |
| positive regulation of chromatin modification | GO:1903310 | 30 | 0.025 | |
| regulation of ubiquitin protein transferase activity | GO:0051438 | 28 | 0.025 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 159 | 0.024 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.024 | |
| cation transmembrane transport | GO:0098655 | 238 | 0.024 | |
| inorganic ion transmembrane transport | GO:0098660 | 231 | 0.024 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.024 | |
| cytokinesis | GO:0000910 | 96 | 0.024 | |
| regulation of immune response | GO:0050776 | 201 | 0.024 | |
| single organism cellular localization | GO:1902580 | 332 | 0.024 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.024 | |
| epidermis morphogenesis | GO:0048730 | 3 | 0.024 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.024 | |
| androgen biosynthetic process | GO:0006702 | 3 | 0.024 | |
| immune response | GO:0006955 | 307 | 0.024 | |
| response to misfolded protein | GO:0051788 | 5 | 0.024 | |
| female gamete generation | GO:0007292 | 2 | 0.024 | |
| response to other organism | GO:0051707 | 261 | 0.024 | |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.023 | |
| nuclear envelope reassembly | GO:0031468 | 3 | 0.023 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.023 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.023 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.023 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.023 | |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.023 | |
| ventricular trabecula myocardium morphogenesis | GO:0003222 | 1 | 0.023 | |
| regulation of cellular response to growth factor stimulus | GO:0090287 | 76 | 0.023 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 4 | 0.023 | |
| mitotic sister chromatid separation | GO:0051306 | 18 | 0.023 | |
| hemopoiesis | GO:0030097 | 180 | 0.023 | |
| cellular response to nutrient levels | GO:0031669 | 69 | 0.023 | |
| glucan metabolic process | GO:0044042 | 22 | 0.023 | |
| protein localization to membrane | GO:0072657 | 160 | 0.023 | |
| positive regulation of cell projection organization | GO:0031346 | 64 | 0.022 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 90 | 0.022 | |
| regulation of nervous system development | GO:0051960 | 88 | 0.022 | |
| system process | GO:0003008 | 349 | 0.022 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.022 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.022 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.022 | Mouse |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.022 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.022 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.022 | |
| energy homeostasis | GO:0097009 | 3 | 0.022 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.022 | |
| actin filament organization | GO:0007015 | 128 | 0.021 | |
| regulation of transporter activity | GO:0032409 | 82 | 0.021 | |
| organ morphogenesis | GO:0009887 | 147 | 0.021 | |
| apoptotic process involved in morphogenesis | GO:0060561 | 3 | 0.021 | |
| steroid biosynthetic process | GO:0006694 | 46 | 0.021 | |
| response to metal ion | GO:0010038 | 84 | 0.021 | |
| multicellular organismal homeostasis | GO:0048871 | 67 | 0.021 | |
| regulation of transforming growth factor beta receptor signaling pathway | GO:0017015 | 48 | 0.021 | |
| metaphase anaphase transition of mitotic cell cycle | GO:0007091 | 21 | 0.021 | |
| response to uv | GO:0009411 | 73 | 0.021 | |
| regulation of cytokine mediated signaling pathway | GO:0001959 | 41 | 0.021 | |
| ion homeostasis | GO:0050801 | 230 | 0.021 | |
| monovalent inorganic cation homeostasis | GO:0055067 | 37 | 0.021 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 35 | 0.021 | |
| retina layer formation | GO:0010842 | 3 | 0.021 | |
| cell projection assembly | GO:0030031 | 126 | 0.021 | |
| establishment of nucleus localization | GO:0040023 | 1 | 0.021 | |
| heart development | GO:0007507 | 95 | 0.021 | |
| maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna | GO:0000466 | 2 | 0.021 | |
| cation homeostasis | GO:0055080 | 189 | 0.021 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.020 | |
| chondrocyte development | GO:0002063 | 1 | 0.020 | |
| negative regulation of chromatin modification | GO:1903309 | 21 | 0.020 | |
| protein secretion | GO:0009306 | 98 | 0.020 | |
| negative regulation of locomotion | GO:0040013 | 118 | 0.020 | |
| regulation of neuronal synaptic plasticity | GO:0048168 | 1 | 0.020 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.020 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.020 | |
| response to transforming growth factor beta | GO:0071559 | 94 | 0.020 | |
| lipid biosynthetic process | GO:0008610 | 177 | 0.020 | |
| er associated misfolded protein catabolic process | GO:0071712 | 1 | 0.020 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.020 | |
| establishment or maintenance of bipolar cell polarity | GO:0061245 | 2 | 0.020 | |
| response to drug | GO:0042493 | 81 | 0.019 | |
| taxis | GO:0042330 | 157 | 0.019 | |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.019 | |
| response to oxidative stress | GO:0006979 | 121 | 0.019 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.019 | |
| cytoskeleton dependent cytokinesis | GO:0061640 | 22 | 0.019 | |
| positive regulation of ubiquitin protein transferase activity | GO:0051443 | 18 | 0.019 | |
| positive regulation of ion transport | GO:0043270 | 87 | 0.019 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.019 | |
| notch signaling pathway | GO:0007219 | 31 | 0.019 | |
| anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process | GO:0031145 | 25 | 0.018 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.018 | |
| lens development in camera type eye | GO:0002088 | 2 | 0.018 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.018 | |
| negative regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032435 | 30 | 0.018 | |
| protein k63 linked deubiquitination | GO:0070536 | 21 | 0.018 | |
| regulation of protein transport | GO:0051223 | 213 | 0.018 | |
| cardiac muscle tissue development | GO:0048738 | 39 | 0.018 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.018 | |
| establishment of apical basal cell polarity | GO:0035089 | 1 | 0.018 | |
| regulation of sister chromatid segregation | GO:0033045 | 27 | 0.018 | |
| negative regulation of response to dna damage stimulus | GO:2001021 | 33 | 0.018 | |
| vesicle organization | GO:0016050 | 62 | 0.018 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.018 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.018 | |
| cellular response to radiation | GO:0071478 | 65 | 0.018 | |
| sodium ion transmembrane transport | GO:0035725 | 59 | 0.018 | |
| autophagy | GO:0006914 | 88 | 0.017 | |
| negative regulation of axonogenesis | GO:0050771 | 4 | 0.017 | |
| cellular response to oxygen levels | GO:0071453 | 55 | 0.017 | |
| protein polymerization | GO:0051258 | 71 | 0.017 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.017 | |
| establishment or maintenance of monopolar cell polarity | GO:0061339 | 1 | 0.017 | |
| cellular response to alcohol | GO:0097306 | 29 | 0.017 | |
| negative regulation of mitotic metaphase anaphase transition | GO:0045841 | 17 | 0.017 | |
| protein n linked glycosylation via asparagine | GO:0018279 | 10 | 0.017 | |
| retrograde transport endosome to golgi | GO:0042147 | 45 | 0.017 | |
| cell projection organization | GO:0030030 | 252 | 0.017 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.017 | |
| peptidyl asparagine modification | GO:0018196 | 11 | 0.017 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.017 | |
| regulation of ossification | GO:0030278 | 58 | 0.017 | |
| steroid metabolic process | GO:0008202 | 94 | 0.017 | |
| membrane fusion | GO:0061025 | 43 | 0.017 | |
| positive regulation of neuron differentiation | GO:0045666 | 40 | 0.016 | |
| regulation of response to oxidative stress | GO:1902882 | 26 | 0.016 | |
| positive regulation of stress activated protein kinase signaling cascade | GO:0070304 | 61 | 0.016 | |
| cellular response to ionizing radiation | GO:0071479 | 32 | 0.016 | |
| cellular response to organic cyclic compound | GO:0071407 | 127 | 0.016 | |
| regulation of leukocyte proliferation | GO:0070663 | 67 | 0.016 | |
| dna replication | GO:0006260 | 116 | 0.016 | |
| regulation of actin filament length | GO:0030832 | 56 | 0.016 | |
| positive regulation of dendrite morphogenesis | GO:0050775 | 3 | 0.016 | |
| calcium ion transport | GO:0006816 | 147 | 0.016 | |
| protein folding | GO:0006457 | 38 | 0.016 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.016 | |
| regulation of cell projection organization | GO:0031344 | 107 | 0.016 | |
| histone h2b conserved c terminal lysine deubiquitination | GO:0035616 | 1 | 0.016 | |
| positive regulation of epithelial cell proliferation | GO:0050679 | 65 | 0.016 | |
| response to lipid | GO:0033993 | 206 | 0.016 | |
| cellular response to extracellular stimulus | GO:0031668 | 72 | 0.016 | |
| response to nutrient levels | GO:0031667 | 81 | 0.016 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.016 | |
| histone h4 k5 acetylation | GO:0043981 | 15 | 0.016 | |
| growth | GO:0040007 | 202 | 0.015 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.015 | |
| t cell activation | GO:0042110 | 99 | 0.015 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.015 | |
| response to alcohol | GO:0097305 | 64 | 0.015 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.015 | |
| regulation of cell growth | GO:0001558 | 135 | 0.015 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.015 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.015 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.015 | |
| mitotic metaphase plate congression | GO:0007080 | 14 | 0.015 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.015 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 45 | 0.015 | |
| organic hydroxy compound biosynthetic process | GO:1901617 | 71 | 0.015 | |
| response to inorganic substance | GO:0010035 | 127 | 0.015 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.015 | Human |
| embryonic organ morphogenesis | GO:0048562 | 24 | 0.015 | |
| substantia nigra development | GO:0021762 | 45 | 0.015 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.015 | |
| microtubule anchoring | GO:0034453 | 24 | 0.015 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.015 | |
| actin polymerization or depolymerization | GO:0008154 | 56 | 0.015 | |
| meiotic chromosome segregation | GO:0045132 | 4 | 0.015 | |
| positive regulation of ligase activity | GO:0051351 | 19 | 0.015 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.015 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.015 | |
| vitamin d receptor signaling pathway | GO:0070561 | 4 | 0.015 | |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.015 | |
| epidermis development | GO:0008544 | 59 | 0.014 | |
| interspecies interaction between organisms | GO:0044419 | 156 | 0.014 | |
| induction of negative chemotaxis | GO:0050929 | 1 | 0.014 | |
| inorganic cation transmembrane transport | GO:0098662 | 194 | 0.014 | |
| regulation of actin polymerization or depolymerization | GO:0008064 | 56 | 0.014 | |
| developmental growth | GO:0048589 | 48 | 0.014 | |
| sodium ion transport | GO:0006814 | 61 | 0.014 | |
| regulation of chromatin organization | GO:1902275 | 56 | 0.014 | |
| positive regulation of neuron projection development | GO:0010976 | 34 | 0.014 | |
| positive regulation of cell adhesion | GO:0045785 | 84 | 0.014 | |
| regulation of protein acetylation | GO:1901983 | 25 | 0.014 | |
| bone mineralization | GO:0030282 | 34 | 0.014 | |
| neuron development | GO:0048666 | 113 | 0.014 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.014 | |
| regulation of mesenchymal stem cell proliferation | GO:1902460 | 1 | 0.014 | |
| rna interference | GO:0016246 | 4 | 0.014 | |
| regulation of actin filament polymerization | GO:0030833 | 50 | 0.014 | |
| cellular response to heparin | GO:0071504 | 2 | 0.014 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 57 | 0.014 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.014 | |
| positive regulation of stem cell differentiation | GO:2000738 | 29 | 0.014 | |
| generation of neurons | GO:0048699 | 152 | 0.014 | |
| epithelium development | GO:0060429 | 227 | 0.014 | |
