| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.834 | Human |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 26 | 0.792 | Human |
| regulation of proteolysis | GO:0030162 | 293 | 0.640 | Human |
| activation of nf kappab inducing kinase activity | GO:0007250 | 9 | 0.569 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.563 | |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.506 | Human Mouse |
| mapk cascade | GO:0000165 | 288 | 0.503 | Human |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 119 | 0.502 | Human |
| lymphocyte mediated immunity | GO:0002449 | 48 | 0.489 | |
| osteoclast differentiation | GO:0030316 | 21 | 0.487 | Human |
| cdc42 protein signal transduction | GO:0032488 | 4 | 0.483 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.479 | Human |
| tnfsf11 mediated signaling pathway | GO:0071847 | 2 | 0.442 | Human |
| positive regulation of stress activated mapk cascade | GO:0032874 | 60 | 0.430 | Human |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.417 | Human |
| regulation of osteoclast differentiation | GO:0045670 | 18 | 0.417 | |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.416 | Human |
| protein polyubiquitination | GO:0000209 | 110 | 0.403 | |
| positive regulation of endothelial cell apoptotic process | GO:2000353 | 8 | 0.398 | Human |
| hemopoiesis | GO:0030097 | 180 | 0.376 | Human |
| positive regulation of map kinase activity | GO:0043406 | 80 | 0.365 | Human |
| cellular response to tumor necrosis factor | GO:0071356 | 63 | 0.356 | Human |
| regulation of map kinase activity | GO:0043405 | 108 | 0.345 | Human |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 0.341 | Human |
| regulation of jnk cascade | GO:0046328 | 73 | 0.323 | Human |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.319 | Human |
| protein autoubiquitination | GO:0051865 | 37 | 0.317 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.317 | Human |
| positive regulation of osteoclast differentiation | GO:0045672 | 9 | 0.294 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.288 | Human |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 81 | 0.287 | Human |
| regulation of cdc42 protein signal transduction | GO:0032489 | 14 | 0.280 | Human |
| regulation of secretion | GO:0051046 | 194 | 0.279 | Mouse |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.275 | Human |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.275 | Human |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.268 | Human |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 132 | 0.268 | Human |
| t cell cytokine production | GO:0002369 | 12 | 0.267 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.267 | Human |
| adaptive immune response | GO:0002250 | 49 | 0.265 | Human |
| activation of protein kinase activity | GO:0032147 | 90 | 0.259 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.257 | Human |
| cellular response to external stimulus | GO:0071496 | 111 | 0.256 | Human |
| cytokine production | GO:0001816 | 247 | 0.253 | Human Mouse |
| activation of immune response | GO:0002253 | 114 | 0.251 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.244 | Human |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.234 | |
| regulation of lymphocyte mediated immunity | GO:0002706 | 33 | 0.232 | |
| response to bacterium | GO:0009617 | 144 | 0.228 | Human Mouse |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.228 | Human |
| positive regulation of immune system process | GO:0002684 | 283 | 0.227 | Mouse |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.224 | Human |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.223 | |
| immune effector process | GO:0002252 | 159 | 0.221 | Mouse |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.214 | Human |
| regulation of kinase activity | GO:0043549 | 314 | 0.213 | Human |
| regulation of erk1 and erk2 cascade | GO:0070372 | 99 | 0.212 | Human |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.207 | Human |
| regulation of jun kinase activity | GO:0043506 | 27 | 0.205 | Human |
| negative regulation of neurological system process | GO:0031645 | 2 | 0.204 | Human |
| leukocyte differentiation | GO:0002521 | 98 | 0.203 | Human |
| positive regulation of immune response | GO:0050778 | 159 | 0.201 | Mouse |
| positive regulation of nik nf kappab signaling | GO:1901224 | 10 | 0.200 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 38 | 0.195 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.195 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.192 | Human |
| nik nf kappab signaling | GO:0038061 | 12 | 0.191 | |
| regulation of cytokine production | GO:0001817 | 232 | 0.190 | Human Mouse |
| rho protein signal transduction | GO:0007266 | 26 | 0.188 | |
| regulation of nik nf kappab signaling | GO:1901222 | 11 | 0.188 | |
| regulation of t cell cytokine production | GO:0002724 | 10 | 0.186 | |
| regulation of complement activation lectin pathway | GO:0001868 | 2 | 0.182 | |
| regulation of adaptive immune response | GO:0002819 | 33 | 0.182 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.182 | Human Mouse |
| immune response regulating signaling pathway | GO:0002764 | 97 | 0.175 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.170 | |
| positive regulation of leukocyte mediated immunity | GO:0002705 | 24 | 0.163 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.161 | Human |
| production of molecular mediator of immune response | GO:0002440 | 37 | 0.155 | Mouse |
| positive regulation of myeloid leukocyte differentiation | GO:0002763 | 24 | 0.154 | |
| cellular response to lipopolysaccharide | GO:0071222 | 57 | 0.154 | Human |
| jnk cascade | GO:0007254 | 80 | 0.145 | Human |
| regulation of endothelial cell apoptotic process | GO:2000351 | 24 | 0.143 | Human |
| myeloid leukocyte differentiation | GO:0002573 | 60 | 0.143 | Human |
| positive regulation of protein binding | GO:0032092 | 24 | 0.143 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.143 | |
| immune response activating signal transduction | GO:0002757 | 90 | 0.140 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 25 | 0.138 | Mouse |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.137 | Human |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.136 | Human |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.133 | Human |
| response to cytokine | GO:0034097 | 232 | 0.132 | Human |
| leukocyte mediated immunity | GO:0002443 | 59 | 0.130 | |
| regulation of immune response | GO:0050776 | 201 | 0.130 | Mouse |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.129 | Human Mouse |
| regulation of peptidase activity | GO:0052547 | 180 | 0.127 | |
| immune response | GO:0006955 | 307 | 0.126 | Human Mouse |
| regulation of protein binding | GO:0043393 | 66 | 0.126 | |
| positive regulation of erk1 and erk2 cascade via tnfsf11 mediated signaling | GO:0071848 | 2 | 0.122 | Human |
| negative regulation of complement activation lectin pathway | GO:0001869 | 2 | 0.121 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 45 | 0.120 | |
| regulation of protein transport | GO:0051223 | 213 | 0.119 | Mouse |
| cellular response to biotic stimulus | GO:0071216 | 71 | 0.119 | Human |
| positive regulation of transcription regulatory region dna binding | GO:2000679 | 8 | 0.119 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.118 | Human |
| protein homooligomerization | GO:0051260 | 100 | 0.116 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.116 | |
| tumor necrosis factor mediated signaling pathway | GO:0033209 | 27 | 0.112 | Human |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.112 | Human |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.112 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.112 | Human |
| nucleotide catabolic process | GO:0009166 | 408 | 0.111 | Human |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.111 | Human |
| myeloid cell differentiation | GO:0030099 | 117 | 0.110 | Human |
| response to lipid | GO:0033993 | 206 | 0.110 | Human |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.110 | Human |
| multicellular organismal homeostasis | GO:0048871 | 67 | 0.109 | |
| positive regulation of ras gtpase activity | GO:0032320 | 117 | 0.108 | Human |
| protein k63 linked ubiquitination | GO:0070534 | 31 | 0.107 | |
| cytokine production involved in immune response | GO:0002367 | 27 | 0.106 | Mouse |
| negative regulation of developmental process | GO:0051093 | 247 | 0.105 | Human |
| protein oligomerization | GO:0051259 | 173 | 0.102 | |
| regulation of binding | GO:0051098 | 111 | 0.102 | |
| regulation of stress activated protein kinase signaling cascade | GO:0070302 | 85 | 0.102 | Human |
| positive regulation of jnk cascade | GO:0046330 | 52 | 0.101 | Human |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.101 | |
| interleukin 2 production | GO:0032623 | 20 | 0.100 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.100 | Human |
| protein trimerization | GO:0070206 | 20 | 0.099 | |
| response to other organism | GO:0051707 | 261 | 0.098 | Human Mouse |
| stress activated protein kinase signaling cascade | GO:0031098 | 94 | 0.097 | Human |
| protein ubiquitination | GO:0016567 | 314 | 0.097 | |
| protein homotrimerization | GO:0070207 | 9 | 0.097 | |
| positive regulation of stress activated protein kinase signaling cascade | GO:0070304 | 61 | 0.097 | Human |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.096 | |
| regulation of protein homodimerization activity | GO:0043496 | 9 | 0.095 | |
| regulation of transcription regulatory region dna binding | GO:2000677 | 15 | 0.095 | |
| positive regulation of t cell cytokine production | GO:0002726 | 4 | 0.095 | |
| cell adhesion | GO:0007155 | 325 | 0.094 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.094 | |
| response to mechanical stimulus | GO:0009612 | 51 | 0.093 | Human |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.093 | Human |
| response to external biotic stimulus | GO:0043207 | 261 | 0.092 | Human Mouse |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 156 | 0.091 | Human |
| positive regulation of myeloid cell differentiation | GO:0045639 | 39 | 0.090 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 62 | 0.090 | Human |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 51 | 0.090 | |
| t cell receptor signaling pathway | GO:0050852 | 21 | 0.088 | |
| neuronal action potential | GO:0019228 | 9 | 0.088 | |
| antigen receptor mediated signaling pathway | GO:0050851 | 38 | 0.088 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.088 | Human |
| cellular cation homeostasis | GO:0030003 | 163 | 0.087 | Human |
| leukocyte activation | GO:0045321 | 164 | 0.087 | Mouse |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.086 | Human |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.086 | Human |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.085 | Human |
| release of cytoplasmic sequestered nf kappab | GO:0008588 | 4 | 0.085 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 29 | 0.085 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.083 | Human |
| regulation of immune effector process | GO:0002697 | 91 | 0.083 | Mouse |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.083 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.081 | Human |
| response to interleukin 1 | GO:0070555 | 47 | 0.081 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.081 | |
| positive regulation of interleukin 2 production | GO:0032743 | 11 | 0.081 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.079 | Human |
| regulation of stress activated mapk cascade | GO:0032872 | 84 | 0.079 | Human |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.077 | |
| protein processing | GO:0016485 | 226 | 0.073 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.073 | |
| secretion by cell | GO:0032940 | 226 | 0.073 | Mouse |
| immune system development | GO:0002520 | 195 | 0.073 | Human |
| action potential | GO:0001508 | 34 | 0.072 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.071 | |
| t cell mediated immunity | GO:0002456 | 25 | 0.070 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.069 | Mouse |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.069 | |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.067 | Mouse |
| positive regulation of binding | GO:0051099 | 45 | 0.066 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.066 | Human |
| response to oxygen containing compound | GO:1901700 | 369 | 0.066 | Human |
| regulation of protein processing | GO:0070613 | 150 | 0.065 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.065 | Human |
| regulation of cell activation | GO:0050865 | 125 | 0.065 | Mouse |
| positive regulation of leukocyte differentiation | GO:1902107 | 37 | 0.065 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.064 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.063 | Human |
| response to lipopolysaccharide | GO:0032496 | 70 | 0.062 | Human |
| protein maturation | GO:0051604 | 233 | 0.062 | |
| positive regulation of jun kinase activity | GO:0043507 | 23 | 0.061 | Human |
| positive regulation of immune effector process | GO:0002699 | 40 | 0.061 | Mouse |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.061 | Human |
| organophosphate catabolic process | GO:0046434 | 430 | 0.061 | Human |
| response to nitric oxide | GO:0071731 | 4 | 0.060 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.060 | |
| positive regulation of rho gtpase activity | GO:0032321 | 56 | 0.060 | Human |
| ras protein signal transduction | GO:0007265 | 73 | 0.059 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.059 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.059 | Human |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 39 | 0.059 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.059 | Human |
| regulation of protein localization | GO:0032880 | 296 | 0.058 | Mouse |
| negative regulation of protein processing | GO:0010955 | 142 | 0.058 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.058 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.056 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.055 | Human |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 51 | 0.054 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.054 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.054 | |
| positive regulation of adaptive immune response | GO:0002821 | 21 | 0.053 | |
| cellular response to lipid | GO:0071396 | 127 | 0.053 | Human |
| regulation of cytokine production involved in immune response | GO:0002718 | 22 | 0.053 | Mouse |
| regulation of lymphocyte activation | GO:0051249 | 103 | 0.052 | Mouse |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.052 | Human |
| lymphocyte activation | GO:0046649 | 133 | 0.052 | Mouse |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 40 | 0.051 | |
| cell activation | GO:0001775 | 213 | 0.050 | Mouse |
| positive regulation of cell activation | GO:0050867 | 81 | 0.050 | |
| positive regulation of lymphocyte activation | GO:0051251 | 73 | 0.049 | |
| response to molecule of bacterial origin | GO:0002237 | 82 | 0.049 | Human |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.048 | |
| regulation of t cell mediated immunity | GO:0002709 | 18 | 0.048 | |
| anion transport | GO:0006820 | 161 | 0.048 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.047 | Human |
| endothelial cell apoptotic process | GO:0072577 | 26 | 0.047 | Human |
| response to biotic stimulus | GO:0009607 | 276 | 0.046 | Human Mouse |
| positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002824 | 19 | 0.046 | |
| transmission of nerve impulse | GO:0019226 | 11 | 0.045 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.045 | Human |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.045 | |
| positive regulation of lymphocyte mediated immunity | GO:0002708 | 23 | 0.043 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.043 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.042 | Human |
| biological adhesion | GO:0022610 | 331 | 0.042 | |
| anatomical structure homeostasis | GO:0060249 | 100 | 0.042 | |
| positive regulation of dna binding | GO:0043388 | 17 | 0.042 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.042 | |
| negative regulation of response to external stimulus | GO:0032102 | 83 | 0.042 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.042 | Human |
| positive regulation of mitochondrion organization | GO:0010822 | 30 | 0.041 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.040 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.039 | Human |
| protein secretion | GO:0009306 | 98 | 0.038 | Mouse |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.037 | |
| neurological system process | GO:0050877 | 163 | 0.037 | Human |
| positive regulation of cell death | GO:0010942 | 263 | 0.036 | Human |
| stress activated mapk cascade | GO:0051403 | 93 | 0.036 | Human |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.036 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.036 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.036 | Human |
| inflammatory response | GO:0006954 | 79 | 0.036 | |
| system process | GO:0003008 | 349 | 0.036 | Human |
| lipid metabolic process | GO:0006629 | 381 | 0.035 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.035 | |
| leukocyte migration | GO:0050900 | 107 | 0.034 | Mouse |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.033 | Human |
| positive regulation of cdc42 gtpase activity | GO:0043089 | 6 | 0.032 | Human |
| chemotaxis | GO:0006935 | 157 | 0.031 | |
| positive regulation of t cell mediated immunity | GO:0002711 | 12 | 0.030 | |
| negative regulation of locomotion | GO:0040013 | 118 | 0.030 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.030 | Human |
| cellular protein complex assembly | GO:0043623 | 188 | 0.030 | |
| single organism cell adhesion | GO:0098602 | 179 | 0.030 | |
| immunoglobulin secretion | GO:0048305 | 1 | 0.030 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.030 | Mouse |
| defense response | GO:0006952 | 315 | 0.029 | Mouse |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.029 | Human |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.029 | Human |
| regulation of cytokine biosynthetic process | GO:0042035 | 35 | 0.029 | Human |
| response to growth factor | GO:0070848 | 205 | 0.029 | |
| lymphocyte apoptotic process | GO:0070227 | 20 | 0.029 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.029 | |
| maintenance of location | GO:0051235 | 112 | 0.028 | |
| negative regulation of myelination | GO:0031642 | 1 | 0.028 | Human |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.028 | Human |
| regulation of cytokine secretion | GO:0050707 | 57 | 0.027 | Mouse |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 25 | 0.027 | Human |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.027 | Human |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.027 | |
| cellular response to mechanical stimulus | GO:0071260 | 39 | 0.027 | Human |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 125 | 0.027 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.027 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.027 | Human |
| positive regulation of protein homodimerization activity | GO:0090073 | 5 | 0.026 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.026 | Mouse |
| amine metabolic process | GO:0009308 | 44 | 0.026 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.026 | |
| regulation of innate immune response | GO:0045088 | 97 | 0.026 | |
| positive regulation of transport | GO:0051050 | 336 | 0.025 | Mouse |
| nucleoside catabolic process | GO:0009164 | 408 | 0.025 | Human |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.025 | Human |
| regulation of immunoglobulin production | GO:0002637 | 4 | 0.025 | |
| post embryonic development | GO:0009791 | 2 | 0.025 | |
| negative regulation of immune system process | GO:0002683 | 136 | 0.025 | Mouse |
| regulation of defense response | GO:0031347 | 154 | 0.024 | |
| postsynaptic membrane organization | GO:0001941 | 2 | 0.024 | |
| positive regulation of immunoglobulin production | GO:0002639 | 4 | 0.024 | |
| mitochondrion organization | GO:0007005 | 156 | 0.024 | |
| lipid transport | GO:0006869 | 90 | 0.024 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.023 | Human |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.023 | |
| positive regulation of immunoglobulin mediated immune response | GO:0002891 | 4 | 0.023 | |
| regulation of rho gtpase activity | GO:0032319 | 66 | 0.023 | Human |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.023 | Human |
| regulation of mitochondrion organization | GO:0010821 | 54 | 0.023 | |
| negative regulation of vasculature development | GO:1901343 | 43 | 0.023 | |
| negative regulation of response to wounding | GO:1903035 | 47 | 0.022 | |
| negative regulation of cysteine type endopeptidase activity | GO:2000117 | 48 | 0.022 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.022 | |
| single organism cellular localization | GO:1902580 | 332 | 0.022 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.022 | Human |
| maintenance of location in cell | GO:0051651 | 62 | 0.021 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.021 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.021 | |
| positive regulation of secretion | GO:0051047 | 116 | 0.021 | Mouse |
| negative regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043154 | 46 | 0.021 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.021 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.021 | Mouse |
| negative regulation of protein activation cascade | GO:2000258 | 7 | 0.021 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.020 | Human |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.020 | |
| lipid localization | GO:0010876 | 106 | 0.020 | |
| cellular homeostasis | GO:0019725 | 196 | 0.020 | Human |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 94 | 0.020 | |
| myeloid leukocyte migration | GO:0097529 | 62 | 0.020 | |
| jak stat cascade | GO:0007259 | 46 | 0.020 | Human |
| regulation of ras gtpase activity | GO:0032318 | 128 | 0.020 | Human |
| regulation of interleukin 2 production | GO:0032663 | 19 | 0.020 | |
| positive regulation of leukocyte activation | GO:0002696 | 80 | 0.020 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 90 | 0.019 | |
| membrane protein ectodomain proteolysis | GO:0006509 | 33 | 0.019 | Human |
| peptide transport | GO:0015833 | 74 | 0.019 | |
| leukocyte chemotaxis | GO:0030595 | 76 | 0.019 | |
| regulation of membrane protein ectodomain proteolysis | GO:0051043 | 17 | 0.019 | Human |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.019 | |
| positive regulation of release of cytochrome c from mitochondria | GO:0090200 | 18 | 0.019 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.019 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.019 | |
| negative regulation of protein transport | GO:0051224 | 75 | 0.019 | |
| dephosphorylation | GO:0016311 | 209 | 0.018 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.018 | Human |
| stem cell division | GO:0017145 | 2 | 0.018 | |
| nervous system development | GO:0007399 | 293 | 0.018 | Human |
| regulation of nervous system development | GO:0051960 | 88 | 0.018 | Human |
| organic anion transport | GO:0015711 | 103 | 0.018 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.018 | |
| tissue homeostasis | GO:0001894 | 63 | 0.018 | |
| positive regulation of protein secretion | GO:0050714 | 60 | 0.018 | Mouse |
| regulation of vesicle mediated transport | GO:0060627 | 130 | 0.018 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.018 | Human |
| programmed necrotic cell death | GO:0097300 | 18 | 0.017 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 207 | 0.017 | |
| secretion | GO:0046903 | 254 | 0.017 | Mouse |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.017 | |
| oogenesis | GO:0048477 | 2 | 0.017 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.017 | |
| positive regulation of membrane protein ectodomain proteolysis | GO:0051044 | 13 | 0.017 | Human |
| regulation of lymphocyte proliferation | GO:0050670 | 64 | 0.017 | Mouse |
| negative regulation of defense response | GO:0031348 | 47 | 0.017 | |
| regulation of anion transport | GO:0044070 | 25 | 0.017 | |
| regulation of protein secretion | GO:0050708 | 86 | 0.016 | Mouse |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.016 | |
| memory | GO:0007613 | 3 | 0.016 | |
| positive regulation of cell adhesion | GO:0045785 | 84 | 0.016 | |
| regulation of interleukin 10 secretion | GO:2001179 | 4 | 0.016 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.016 | |
| interleukin 12 secretion | GO:0072610 | 1 | 0.016 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.016 | |
| triglyceride metabolic process | GO:0006641 | 23 | 0.016 | |
| response to wounding | GO:0009611 | 168 | 0.016 | |
| regulation of wound healing | GO:0061041 | 56 | 0.016 | |
| phospholipid metabolic process | GO:0006644 | 99 | 0.016 | |
| positive regulation of rac gtpase activity | GO:0032855 | 31 | 0.016 | Human |
| membrane organization | GO:0061024 | 292 | 0.016 | |
| female gamete generation | GO:0007292 | 2 | 0.016 | |
| cell substrate adhesion | GO:0031589 | 132 | 0.016 | |
| negative regulation of immune response | GO:0050777 | 40 | 0.016 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.016 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 49 | 0.015 | |
| lipid biosynthetic process | GO:0008610 | 177 | 0.015 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.015 | |
| protein import | GO:0017038 | 130 | 0.015 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.015 | |
| positive regulation of cytokine production involved in immune response | GO:0002720 | 6 | 0.015 | Mouse |
| lipid modification | GO:0030258 | 84 | 0.015 | |
| fatty acid metabolic process | GO:0006631 | 115 | 0.015 | |
| multicellular organismal signaling | GO:0035637 | 34 | 0.015 | |
| regulation of dna binding | GO:0051101 | 37 | 0.015 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 57 | 0.015 | |
| single organismal cell cell adhesion | GO:0016337 | 148 | 0.015 | |
| protein catabolic process | GO:0030163 | 325 | 0.015 | Human |
| leukocyte apoptotic process | GO:0071887 | 31 | 0.015 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.014 | Human |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.014 | |
| plasma lipoprotein particle clearance | GO:0034381 | 16 | 0.014 | |
| positive regulation of bone resorption | GO:0045780 | 2 | 0.014 | |
| regulation of intracellular protein transport | GO:0033157 | 123 | 0.014 | |
| regulation of immunoglobulin secretion | GO:0051023 | 1 | 0.014 | |
| cytokine metabolic process | GO:0042107 | 38 | 0.014 | Human |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.014 | |
| chloride transport | GO:0006821 | 41 | 0.014 | |
| regulation of response to wounding | GO:1903034 | 101 | 0.014 | |
| organic acid transport | GO:0015849 | 65 | 0.014 | |
| intracellular protein transport | GO:0006886 | 270 | 0.014 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.014 | |
| maintenance of protein location in cell | GO:0032507 | 56 | 0.014 | |
| blood vessel development | GO:0001568 | 172 | 0.014 | |
| regulation of cell migration | GO:0030334 | 289 | 0.014 | Mouse |
| determination of adult lifespan | GO:0008340 | 2 | 0.014 | |
| microtubule based process | GO:0007017 | 210 | 0.014 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.014 | |
| cytokine secretion | GO:0050663 | 64 | 0.014 | Mouse |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.014 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.013 | |
| response to inorganic substance | GO:0010035 | 127 | 0.013 | |
| negative regulation of intracellular transport | GO:0032387 | 60 | 0.013 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.013 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.013 | Human |
| neuroblast proliferation | GO:0007405 | 4 | 0.013 | |
| regulation of inflammatory response | GO:0050727 | 46 | 0.013 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.013 | Human |
| nitrogen compound transport | GO:0071705 | 191 | 0.013 | |
| ectoderm development | GO:0007398 | 3 | 0.013 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.013 | |
| cell projection organization | GO:0030030 | 252 | 0.013 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.013 | Human |
| segmentation | GO:0035282 | 4 | 0.013 | |
| protein kinase c activating g protein coupled receptor signaling pathway | GO:0007205 | 2 | 0.013 | |
| regulation of rho protein signal transduction | GO:0035023 | 79 | 0.013 | Human |
| positive regulation of organic acid transport | GO:0032892 | 3 | 0.013 | |
| cellular response to muramyl dipeptide | GO:0071225 | 3 | 0.013 | |
| innate immune response | GO:0045087 | 178 | 0.013 | |
| glycerophospholipid metabolic process | GO:0006650 | 84 | 0.013 | |
| actin filament based process | GO:0030029 | 224 | 0.013 | |
| spermatid differentiation | GO:0048515 | 4 | 0.013 | |
| monocarboxylic acid metabolic process | GO:0032787 | 185 | 0.013 | |
| extrinsic apoptotic signaling pathway via death domain receptors | GO:0008625 | 42 | 0.013 | |
| negative regulation of humoral immune response | GO:0002921 | 7 | 0.013 | |
| oocyte development | GO:0048599 | 1 | 0.013 | |
| positive regulation of dna metabolic process | GO:0051054 | 73 | 0.012 | |
| negative regulation of cytoplasmic transport | GO:1903650 | 46 | 0.012 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 75 | 0.012 | Human |
| acylglycerol metabolic process | GO:0006639 | 27 | 0.012 | |
| negative regulation of alpha beta t cell activation | GO:0046636 | 3 | 0.012 | Mouse |
| regulation of synaptic plasticity | GO:0048167 | 3 | 0.012 | |
| cell projection assembly | GO:0030031 | 126 | 0.012 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.012 | Human |
| positive regulation of icosanoid secretion | GO:0032305 | 3 | 0.012 | |
| negative regulation of nucleocytoplasmic transport | GO:0046823 | 37 | 0.012 | |
| negative regulation of cell motility | GO:2000146 | 104 | 0.012 | |
| regulation of cellular response to growth factor stimulus | GO:0090287 | 76 | 0.012 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.012 | |
| post embryonic organ development | GO:0048569 | 1 | 0.012 | |
| regulation of myelination | GO:0031641 | 1 | 0.012 | Human |
| blastoderm segmentation | GO:0007350 | 2 | 0.012 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.012 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.012 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 108 | 0.012 | Human Mouse |
| small molecule catabolic process | GO:0044282 | 92 | 0.012 | |
| cation homeostasis | GO:0055080 | 189 | 0.012 | Human |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 76 | 0.012 | |
| response to transforming growth factor beta | GO:0071559 | 94 | 0.012 | |
| leukocyte proliferation | GO:0070661 | 74 | 0.011 | Mouse |
| somatic muscle development | GO:0007525 | 1 | 0.011 | |
| protein localization to membrane | GO:0072657 | 160 | 0.011 | |
| single organism membrane organization | GO:0044802 | 268 | 0.011 | |
| apoptotic mitochondrial changes | GO:0008637 | 57 | 0.011 | |
| glycerolipid biosynthetic process | GO:0045017 | 51 | 0.011 | |
| regulation of icosanoid secretion | GO:0032303 | 4 | 0.011 | |
| vasculature development | GO:0001944 | 181 | 0.011 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.011 | |
| negative regulation of protein import into nucleus | GO:0042308 | 30 | 0.011 | |
| positive regulation of b cell mediated immunity | GO:0002714 | 4 | 0.011 | |
| glycerolipid metabolic process | GO:0046486 | 107 | 0.011 | |
| positive regulation of fatty acid transport | GO:2000193 | 3 | 0.011 | |
| gtp catabolic process | GO:0006184 | 237 | 0.011 | Human |
| transcription factor import into nucleus | GO:0042991 | 40 | 0.011 | |
| negative regulation of transport | GO:0051051 | 176 | 0.011 | |
| positive regulation of lipid storage | GO:0010884 | 10 | 0.011 | |
| regulation of endocytosis | GO:0030100 | 72 | 0.011 | |
| chemokine production | GO:0032602 | 32 | 0.011 | |