| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.926 | Human |
| regulation of protein secretion | GO:0050708 | 86 | 0.899 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.884 | |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.884 | Human Mouse Rat |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.884 | |
| hemopoiesis | GO:0030097 | 180 | 0.866 | Human |
| membrane protein proteolysis | GO:0033619 | 38 | 0.838 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.834 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 52 | 0.829 | |
| osteoclast differentiation | GO:0030316 | 21 | 0.812 | Human |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.811 | |
| cellular response to biotic stimulus | GO:0071216 | 71 | 0.810 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.806 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.776 | |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.771 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.759 | |
| negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001240 | 16 | 0.739 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.714 | |
| immune system development | GO:0002520 | 195 | 0.710 | Human |
| adaptive immune response | GO:0002250 | 49 | 0.708 | Human |
| amine metabolic process | GO:0009308 | 44 | 0.708 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.703 | Human |
| membrane protein ectodomain proteolysis | GO:0006509 | 33 | 0.703 | |
| positive regulation of cytokine secretion | GO:0050715 | 42 | 0.692 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.690 | |
| secretion | GO:0046903 | 254 | 0.684 | |
| response to cytokine | GO:0034097 | 232 | 0.681 | Human Mouse Rat |
| positive regulation of map kinase activity | GO:0043406 | 80 | 0.677 | Human |
| chronic inflammatory response | GO:0002544 | 2 | 0.674 | |
| positive regulation of tumor necrosis factor superfamily cytokine production | GO:1903557 | 22 | 0.673 | |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.668 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.660 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.657 | Human Mouse |
| positive regulation of secretion by cell | GO:1903532 | 108 | 0.653 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 62 | 0.641 | |
| positive regulation of interleukin 8 biosynthetic process | GO:0045416 | 8 | 0.622 | |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 132 | 0.618 | Human |
| regulation of protein localization | GO:0032880 | 296 | 0.615 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.614 | Human |
| positive regulation of jun kinase activity | GO:0043507 | 23 | 0.581 | Human |
| secretion by cell | GO:0032940 | 226 | 0.572 | |
| signal release | GO:0023061 | 70 | 0.566 | |
| regulation of cytokine production involved in immune response | GO:0002718 | 22 | 0.563 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.559 | Human |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.559 | |
| heterotypic cell cell adhesion | GO:0034113 | 28 | 0.558 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 39 | 0.546 | |
| lymphocyte activation | GO:0046649 | 133 | 0.530 | |
| biological adhesion | GO:0022610 | 331 | 0.529 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.527 | |
| regulation of protein transport | GO:0051223 | 213 | 0.525 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.524 | Human |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.512 | Human |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.489 | |
| cytokine production involved in immune response | GO:0002367 | 27 | 0.481 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.477 | Human |
| cellular extravasation | GO:0045123 | 21 | 0.476 | |
| production of molecular mediator of immune response | GO:0002440 | 37 | 0.473 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.458 | Human |
| negative regulation of developmental process | GO:0051093 | 247 | 0.452 | Human |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.445 | |
| protein targeting to nucleus | GO:0044744 | 104 | 0.443 | |
| lipid catabolic process | GO:0016042 | 84 | 0.434 | |
| regulation of osteoclast differentiation | GO:0045670 | 18 | 0.429 | |
| positive regulation of calcidiol 1 monooxygenase activity | GO:0060559 | 3 | 0.427 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 39 | 0.423 | |
| positive regulation of osteoclast differentiation | GO:0045672 | 9 | 0.413 | |
| response to molecule of bacterial origin | GO:0002237 | 82 | 0.410 | |
| protein catabolic process | GO:0030163 | 325 | 0.408 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.407 | |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.406 | Human Mouse Rat |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.391 | Human |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 108 | 0.391 | Human |
| response to lipid | GO:0033993 | 206 | 0.389 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.387 | |
| leukocyte migration | GO:0050900 | 107 | 0.384 | |
| regulation of cytokine production | GO:0001817 | 232 | 0.383 | |
| protein localization to organelle | GO:0033365 | 280 | 0.383 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 119 | 0.380 | Human |
| regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001239 | 20 | 0.380 | |
| positive regulation of jak stat cascade | GO:0046427 | 35 | 0.379 | Human |
| regulation of lipid catabolic process | GO:0050994 | 23 | 0.375 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.371 | |
| negative regulation of signal transduction in absence of ligand | GO:1901099 | 16 | 0.370 | |
| epithelial tube branching involved in lung morphogenesis | GO:0060441 | 4 | 0.370 | |
| regulation of stress activated protein kinase signaling cascade | GO:0070302 | 85 | 0.368 | Human |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.365 | Human Mouse |
| leukocyte differentiation | GO:0002521 | 98 | 0.357 | Human |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.356 | |
| cellular response to lipopolysaccharide | GO:0071222 | 57 | 0.352 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.341 | Human |
| regulation of secretion | GO:0051046 | 194 | 0.338 | |
| response to lipopolysaccharide | GO:0032496 | 70 | 0.335 | |
| chemical homeostasis | GO:0048878 | 306 | 0.331 | Human |
| leukocyte activation | GO:0045321 | 164 | 0.331 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.331 | Human |
| negative regulation of lipid catabolic process | GO:0050995 | 9 | 0.326 | |
| negative regulation of immune system process | GO:0002683 | 136 | 0.323 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.318 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 49 | 0.315 | |
| single organism cellular localization | GO:1902580 | 332 | 0.313 | |
| single organism nuclear import | GO:1902593 | 104 | 0.312 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.306 | |
| immune effector process | GO:0002252 | 159 | 0.306 | |
| positive regulation of secretion | GO:0051047 | 116 | 0.303 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.303 | Human |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.302 | Human |
| positive regulation of jnk cascade | GO:0046330 | 52 | 0.301 | Human |
| regulation of lymphocyte proliferation | GO:0050670 | 64 | 0.299 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.296 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.291 | |
| protein secretion | GO:0009306 | 98 | 0.291 | |
| positive regulation of heterotypic cell cell adhesion | GO:0034116 | 8 | 0.288 | |
| regulation of leukocyte differentiation | GO:1902105 | 61 | 0.285 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.281 | |
| cell cell signaling | GO:0007267 | 155 | 0.281 | |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.279 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.278 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.271 | Human |
| nuclear import | GO:0051170 | 106 | 0.271 | |
| regulation of jnk cascade | GO:0046328 | 73 | 0.270 | Human |
| reactive nitrogen species metabolic process | GO:2001057 | 3 | 0.262 | |
| response to alcohol | GO:0097305 | 64 | 0.262 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.257 | |
| positive regulation of protein secretion | GO:0050714 | 60 | 0.254 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.253 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.252 | Human |
| lipid metabolic process | GO:0006629 | 381 | 0.252 | |
| intracellular protein transport | GO:0006886 | 270 | 0.251 | |
| positive regulation of smooth muscle cell proliferation | GO:0048661 | 14 | 0.251 | |
| cytokine production | GO:0001816 | 247 | 0.249 | |
| vitamin metabolic process | GO:0006766 | 26 | 0.241 | |
| neurological system process | GO:0050877 | 163 | 0.240 | Human |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 22 | 0.240 | |
| response to bacterium | GO:0009617 | 144 | 0.239 | |
| regulation of chemokine production | GO:0032642 | 31 | 0.236 | |
| activation of protein kinase activity | GO:0032147 | 90 | 0.234 | |
| inflammatory response to antigenic stimulus | GO:0002437 | 4 | 0.233 | |
| blood vessel morphogenesis | GO:0048514 | 162 | 0.226 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.226 | |
| neurotransmitter secretion | GO:0007269 | 4 | 0.217 | |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.217 | Human |
| positive regulation of membrane protein ectodomain proteolysis | GO:0051044 | 13 | 0.216 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.215 | Human |
| response to other organism | GO:0051707 | 261 | 0.212 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.211 | Human |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.210 | Human |
| mononuclear cell proliferation | GO:0032943 | 71 | 0.210 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.209 | Human |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.208 | |
| single organismal cell cell adhesion | GO:0016337 | 148 | 0.206 | |
| alcohol metabolic process | GO:0006066 | 114 | 0.203 | |
| protein targeting | GO:0006605 | 187 | 0.203 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.203 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.203 | |
| positive regulation of steroid metabolic process | GO:0045940 | 13 | 0.201 | |
| taxis | GO:0042330 | 157 | 0.200 | |
| regulation of tyrosine phosphorylation of stat protein | GO:0042509 | 30 | 0.199 | Human |
| leukocyte cell cell adhesion | GO:0007159 | 37 | 0.199 | |
| cellular response to alkaloid | GO:0071312 | 11 | 0.197 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.195 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.193 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.193 | |
| muscle cell proliferation | GO:0033002 | 35 | 0.193 | |
| programmed necrotic cell death | GO:0097300 | 18 | 0.192 | |
| negative regulation of production of molecular mediator of immune response | GO:0002701 | 13 | 0.192 | |
| positive regulation of chemokine production | GO:0032722 | 22 | 0.191 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.190 | |
| peptide secretion | GO:0002790 | 51 | 0.190 | |
| positive regulation of stress activated protein kinase signaling cascade | GO:0070304 | 61 | 0.189 | Human |
| jnk cascade | GO:0007254 | 80 | 0.189 | Human |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.189 | Human |
| response to external biotic stimulus | GO:0043207 | 261 | 0.186 | |
| negative regulation of immune response | GO:0050777 | 40 | 0.185 | |
| regulation of leukocyte proliferation | GO:0070663 | 67 | 0.184 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.183 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 37 | 0.182 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.181 | |
| protein import | GO:0017038 | 130 | 0.181 | |
| positive regulation of tyrosine phosphorylation of stat protein | GO:0042531 | 28 | 0.180 | Human |
| response to biotic stimulus | GO:0009607 | 276 | 0.180 | |
| cardiovascular system development | GO:0072358 | 262 | 0.180 | |
| regulation of vitamin d biosynthetic process | GO:0060556 | 8 | 0.174 | |
| positive regulation of transcription factor import into nucleus | GO:0042993 | 25 | 0.174 | |
| nuclear transport | GO:0051169 | 179 | 0.171 | |
| fat soluble vitamin metabolic process | GO:0006775 | 19 | 0.171 | |
| cellular response to tumor necrosis factor | GO:0071356 | 63 | 0.168 | Human Mouse Rat |
| organophosphate catabolic process | GO:0046434 | 430 | 0.166 | Human |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.165 | Human |
| negative regulation of immune effector process | GO:0002698 | 38 | 0.165 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.163 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 3 | 0.163 | |
| activation of mapkkk activity | GO:0000185 | 7 | 0.161 | |
| regulation of oxidoreductase activity | GO:0051341 | 43 | 0.160 | |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 45 | 0.160 | |
| regulation of heterotypic cell cell adhesion | GO:0034114 | 14 | 0.160 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.159 | Human |
| positive regulation of myeloid leukocyte differentiation | GO:0002763 | 24 | 0.159 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 25 | 0.158 | |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 25 | 0.154 | |
| positive regulation of vitamin d biosynthetic process | GO:0060557 | 3 | 0.154 | |
| defense response | GO:0006952 | 315 | 0.153 | Mouse |
| protein oligomerization | GO:0051259 | 173 | 0.153 | |
| protein complex disassembly | GO:0043241 | 52 | 0.152 | |
| cell adhesion | GO:0007155 | 325 | 0.151 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.148 | |
| cytokine secretion | GO:0050663 | 64 | 0.145 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.145 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.144 | |
| signal transduction in absence of ligand | GO:0038034 | 22 | 0.142 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.141 | Human |
| positive regulation of lipid biosynthetic process | GO:0046889 | 22 | 0.141 | |
| extrinsic apoptotic signaling pathway via death domain receptors | GO:0008625 | 42 | 0.141 | |
| macromolecular complex disassembly | GO:0032984 | 60 | 0.140 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.139 | Human |
| peptide transport | GO:0015833 | 74 | 0.139 | |
| regulation of smooth muscle cell proliferation | GO:0048660 | 28 | 0.139 | |
| positive regulation of protein import into nucleus | GO:0042307 | 46 | 0.139 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.138 | |
| positive regulation of cell adhesion | GO:0045785 | 84 | 0.138 | |
| regulation of lymphocyte activation | GO:0051249 | 103 | 0.137 | |
| negative regulation of secretion by cell | GO:1903531 | 52 | 0.137 | |
| receptor metabolic process | GO:0043112 | 81 | 0.136 | |
| activation of mapk activity | GO:0000187 | 45 | 0.136 | |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.136 | Human |
| vasculature development | GO:0001944 | 181 | 0.136 | |
| response to nitric oxide | GO:0071731 | 4 | 0.135 | |
| hormone secretion | GO:0046879 | 65 | 0.135 | |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.134 | Human |
| interleukin 6 production | GO:0032635 | 37 | 0.132 | |
| cellular homeostasis | GO:0019725 | 196 | 0.131 | Human |
| regulation of podosome assembly | GO:0071801 | 5 | 0.129 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 158 | 0.129 | |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 44 | 0.127 | |
| immune response | GO:0006955 | 307 | 0.126 | Human Rat |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.125 | Human |
| protein import into nucleus | GO:0006606 | 104 | 0.124 | |
| regulation of map kinase activity | GO:0043405 | 108 | 0.124 | Human |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.123 | Human |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 40 | 0.122 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.121 | |
| small molecule biosynthetic process | GO:0044283 | 157 | 0.121 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 4 | 0.121 | |
| regulation of protein localization to nucleus | GO:1900180 | 85 | 0.120 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 81 | 0.118 | Human |
| lung morphogenesis | GO:0060425 | 6 | 0.118 | |
| cellular component disassembly | GO:0022411 | 92 | 0.118 | |
| epithelium development | GO:0060429 | 227 | 0.117 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.117 | Human |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.116 | Human |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.114 | Human |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.113 | |
| regulation of immune response | GO:0050776 | 201 | 0.112 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.111 | |
| tyrosine phosphorylation of stat protein | GO:0007260 | 33 | 0.111 | Human |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.109 | Human |
| negative regulation of neurological system process | GO:0031645 | 2 | 0.109 | Human |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.109 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.108 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.107 | Human |
| cytokine biosynthetic process | GO:0042089 | 37 | 0.104 | |
| steroid metabolic process | GO:0008202 | 94 | 0.104 | |
| positive regulation of tumor necrosis factor production | GO:0032760 | 21 | 0.103 | |
| chemokine production | GO:0032602 | 32 | 0.103 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.102 | Human |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.102 | |
| blood vessel development | GO:0001568 | 172 | 0.102 | |
| positive regulation of lipid metabolic process | GO:0045834 | 50 | 0.101 | |
| regulation of protein targeting | GO:1903533 | 91 | 0.101 | |
| chemokine c x c motif ligand 2 production | GO:0072567 | 3 | 0.100 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.100 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.100 | Human |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.098 | Human |
| positive regulation of protein localization to nucleus | GO:1900182 | 48 | 0.097 | |
| regulation of rho protein signal transduction | GO:0035023 | 79 | 0.097 | Human |
| positive regulation of cell death | GO:0010942 | 263 | 0.094 | Human |
| negative regulation of alpha beta t cell activation | GO:0046636 | 3 | 0.094 | |
| cellular response to lipid | GO:0071396 | 127 | 0.093 | |
| protein localization to membrane | GO:0072657 | 160 | 0.093 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.092 | |
| neuron projection development | GO:0031175 | 106 | 0.092 | |
| nervous system development | GO:0007399 | 293 | 0.091 | Human |
| leukocyte mediated immunity | GO:0002443 | 59 | 0.091 | |
| chemokine metabolic process | GO:0050755 | 4 | 0.090 | |
| protein kinase b signaling | GO:0043491 | 69 | 0.090 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.090 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.090 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.090 | |
| protein maturation | GO:0051604 | 233 | 0.090 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.088 | Human |
| regulation of immune effector process | GO:0002697 | 91 | 0.087 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.087 | Human |
| multi organism cellular process | GO:0044764 | 156 | 0.086 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.086 | Human Mouse Rat |
| membrane organization | GO:0061024 | 292 | 0.085 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.084 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.082 | Human |
| regulation of proteolysis | GO:0030162 | 293 | 0.082 | |
| single organism cell adhesion | GO:0098602 | 179 | 0.081 | |
| response to alkaloid | GO:0043279 | 20 | 0.080 | |
| regulation of stress activated mapk cascade | GO:0032872 | 84 | 0.080 | Human |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.079 | |
| tumor necrosis factor production | GO:0032640 | 43 | 0.079 | |
| positive regulation of transport | GO:0051050 | 336 | 0.079 | |
| positive regulation of intracellular protein transport | GO:0090316 | 76 | 0.079 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.079 | |
| positive regulation of cell activation | GO:0050867 | 81 | 0.079 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 35 | 0.079 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.078 | |
| negative regulation of protein complex disassembly | GO:0043242 | 20 | 0.078 | |
| positive regulation of nfat protein import into nucleus | GO:0051533 | 3 | 0.077 | |
| mature natural killer cell chemotaxis | GO:0035782 | 1 | 0.077 | |
| protein processing | GO:0016485 | 226 | 0.077 | |
| regulation of interleukin 6 production | GO:0032675 | 37 | 0.077 | |
| positive regulation of interleukin 8 production | GO:0032757 | 36 | 0.076 | |
| inflammatory response | GO:0006954 | 79 | 0.076 | Mouse |
| regulation of hormone secretion | GO:0046883 | 57 | 0.075 | |
| cell development | GO:0048468 | 328 | 0.075 | |
| mapk cascade | GO:0000165 | 288 | 0.074 | Human |
| regulation of cell adhesion | GO:0030155 | 166 | 0.073 | |
| regulation of cell cell adhesion | GO:0022407 | 57 | 0.073 | |
| response to ethanol | GO:0045471 | 11 | 0.072 | |
| regulation of symbiosis encompassing mutualism through parasitism | GO:0043903 | 109 | 0.072 | |
| leukocyte proliferation | GO:0070661 | 74 | 0.071 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.071 | |
| post embryonic development | GO:0009791 | 2 | 0.071 | |
| smooth muscle cell proliferation | GO:0048659 | 28 | 0.071 | |
| regulation of viral genome replication | GO:0045069 | 48 | 0.071 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 39 | 0.069 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.069 | Mouse |
| response to heat | GO:0009408 | 21 | 0.069 | |
| atp metabolic process | GO:0046034 | 176 | 0.068 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.068 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 0.068 | Human |
| nucleoside monophosphate catabolic process | GO:0009125 | 159 | 0.068 | |
| regulation of cytokine secretion | GO:0050707 | 57 | 0.068 | |
| steroid biosynthetic process | GO:0006694 | 46 | 0.068 | |
| insulin secretion | GO:0030073 | 39 | 0.068 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.068 | Human |
| zymogen activation | GO:0031638 | 70 | 0.066 | |
| regulation of protein import into nucleus | GO:0042306 | 78 | 0.066 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.066 | |
| intracellular protein transmembrane transport | GO:0065002 | 24 | 0.066 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 158 | 0.065 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 94 | 0.065 | Human |
| negative regulation of secretion | GO:0051048 | 58 | 0.065 | |
| regulation of lipid metabolic process | GO:0019216 | 96 | 0.065 | |
| protein import into nucleus translocation | GO:0000060 | 22 | 0.065 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 75 | 0.065 | Human |
| regulation of peptide transport | GO:0090087 | 62 | 0.064 | |
| negative regulation of cytokine production involved in immune response | GO:0002719 | 13 | 0.064 | |
| maintenance of location | GO:0051235 | 112 | 0.064 | |
| regulation of homeostatic process | GO:0032844 | 121 | 0.064 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.064 | Human |
| granulocyte migration | GO:0097530 | 40 | 0.063 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.063 | |
| response to lipoteichoic acid | GO:0070391 | 3 | 0.063 | |
| cytokine metabolic process | GO:0042107 | 38 | 0.063 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.063 | Human |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.063 | Human |
| growth | GO:0040007 | 202 | 0.063 | |
| regulation of intracellular protein transport | GO:0033157 | 123 | 0.062 | |
| viral process | GO:0016032 | 146 | 0.062 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.062 | Human |
| response to organic cyclic compound | GO:0014070 | 204 | 0.062 | |
| regulation of lipid biosynthetic process | GO:0046890 | 47 | 0.061 | |
| interleukin 8 production | GO:0032637 | 51 | 0.061 | |
| cell morphogenesis | GO:0000902 | 296 | 0.060 | |
| immune response activating signal transduction | GO:0002757 | 90 | 0.060 | |
| regulation of steroid metabolic process | GO:0019218 | 32 | 0.060 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.060 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.059 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 156 | 0.058 | |
| hormone transport | GO:0009914 | 68 | 0.058 | |
| calcium ion homeostasis | GO:0055074 | 122 | 0.057 | Human |
| receptor biosynthetic process | GO:0032800 | 18 | 0.055 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.055 | |
| lymphocyte apoptotic process | GO:0070227 | 20 | 0.055 | |
| negative regulation of defense response | GO:0031348 | 47 | 0.054 | Mouse |
| positive regulation of defense response | GO:0031349 | 87 | 0.054 | |
| regulation of tumor necrosis factor production | GO:0032680 | 43 | 0.054 | |
| mitochondrion organization | GO:0007005 | 156 | 0.053 | |
| organ morphogenesis | GO:0009887 | 147 | 0.053 | |
| single organism membrane organization | GO:0044802 | 268 | 0.053 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.052 | Human |
| circulatory system development | GO:0072359 | 262 | 0.051 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.051 | |
| positive regulation of alcohol biosynthetic process | GO:1902932 | 9 | 0.051 | |
| cation transport | GO:0006812 | 331 | 0.051 | |
| regulation of growth | GO:0040008 | 165 | 0.051 | |
| response to nicotine | GO:0035094 | 12 | 0.051 | |
| viral life cycle | GO:0019058 | 132 | 0.050 | |
| regulation of immunoglobulin production | GO:0002637 | 4 | 0.050 | |
| granulocyte chemotaxis | GO:0071621 | 37 | 0.049 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.049 | Mouse |
| vitamin d metabolic process | GO:0042359 | 10 | 0.049 | |
| cytokine secretion involved in immune response | GO:0002374 | 7 | 0.049 | |
| regulation of hormone levels | GO:0010817 | 125 | 0.048 | |
| positive regulation of intracellular transport | GO:0032388 | 104 | 0.047 | |
| positive regulation of organelle assembly | GO:1902117 | 17 | 0.047 | |
| regulation of jun kinase activity | GO:0043506 | 27 | 0.047 | Human |
| homeostasis of number of cells | GO:0048872 | 40 | 0.047 | |
| regulation of steroid biosynthetic process | GO:0050810 | 23 | 0.047 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.047 | |
| response to steroid hormone | GO:0048545 | 80 | 0.046 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.046 | |
| regulation of locomotion | GO:0040012 | 329 | 0.046 | |
| regulation of insulin secretion | GO:0050796 | 33 | 0.046 | |
| negative regulation of lipid metabolic process | GO:0045833 | 38 | 0.045 | |
| neurogenesis | GO:0022008 | 169 | 0.045 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 99 | 0.045 | Human |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 26 | 0.045 | |
| transcription factor import into nucleus | GO:0042991 | 40 | 0.045 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.045 | |
| rna catabolic process | GO:0006401 | 71 | 0.044 | |
| cdc42 protein signal transduction | GO:0032488 | 4 | 0.044 | |
| lipid biosynthetic process | GO:0008610 | 177 | 0.043 | |
| morphogenesis of an epithelium | GO:0002009 | 60 | 0.043 | |
| positive regulation of vitamin metabolic process | GO:0046136 | 3 | 0.043 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.042 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 98 | 0.042 | |
| regulation of chemokine biosynthetic process | GO:0045073 | 4 | 0.042 | |
| negative regulation of protein transport | GO:0051224 | 75 | 0.042 | |
| sequestering of triglyceride | GO:0030730 | 11 | 0.041 | |
| positive regulation of peptidyl serine phosphorylation | GO:0033138 | 42 | 0.041 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.041 | Human |
| regulation of viral process | GO:0050792 | 103 | 0.041 | |
| chemotaxis | GO:0006935 | 157 | 0.040 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 29 | 0.040 | |
| regulation of peptide secretion | GO:0002791 | 42 | 0.040 | |
| regulation of cell motility | GO:2000145 | 299 | 0.040 | |
| response to virus | GO:0009615 | 126 | 0.040 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.040 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.040 | Human |
| organic hydroxy compound biosynthetic process | GO:1901617 | 71 | 0.040 | |
| positive regulation of leukocyte migration | GO:0002687 | 46 | 0.040 | |
| amide transport | GO:0042886 | 76 | 0.039 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.039 | |
| generation of neurons | GO:0048699 | 152 | 0.039 | |
| cell projection organization | GO:0030030 | 252 | 0.039 | |
| positive regulation of ras gtpase activity | GO:0032320 | 117 | 0.039 | Human |
| positive regulation of macrophage chemotaxis | GO:0010759 | 3 | 0.039 | |
| rna interference | GO:0016246 | 4 | 0.039 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.038 | |
| cell growth | GO:0016049 | 160 | 0.038 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.038 | |
| neuron differentiation | GO:0030182 | 138 | 0.037 | |
| establishment of lymphocyte polarity | GO:0001767 | 2 | 0.037 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.037 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.037 | Human |
| cell projection morphogenesis | GO:0048858 | 129 | 0.037 | |
| positive regulation of immunoglobulin mediated immune response | GO:0002891 | 4 | 0.036 | |
| mitochondrial transport | GO:0006839 | 60 | 0.036 | |
| action potential | GO:0001508 | 34 | 0.036 | |
| regulation of peptide hormone secretion | GO:0090276 | 41 | 0.036 | |
| regulation of interleukin 8 production | GO:0032677 | 49 | 0.036 | |
| regulation of cell migration | GO:0030334 | 289 | 0.036 | |
| cell activation | GO:0001775 | 213 | 0.035 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 57 | 0.035 | |
| positive regulation of acute inflammatory response | GO:0002675 | 2 | 0.035 | |
| regulation of inflammatory response | GO:0050727 | 46 | 0.035 | Mouse |
| negative regulation of viral process | GO:0048525 | 66 | 0.034 | |
| negative regulation of nervous system development | GO:0051961 | 28 | 0.034 | Human |
| establishment of protein localization to mitochondrion | GO:0072655 | 22 | 0.034 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.034 | Human |
| regulation of protein localization to cell surface | GO:2000008 | 15 | 0.034 | |
| protein refolding | GO:0042026 | 14 | 0.034 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.034 | Human |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 82 | 0.033 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.033 | |
| atp catabolic process | GO:0006200 | 157 | 0.033 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.033 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.033 | Human |
| actin filament based process | GO:0030029 | 224 | 0.033 | |
| positive regulation of lymphocyte proliferation | GO:0050671 | 46 | 0.033 | |
| negative regulation of protein secretion | GO:0050709 | 29 | 0.033 | |
| positive regulation of protein complex assembly | GO:0031334 | 86 | 0.033 | |
| response to electrical stimulus | GO:0051602 | 1 | 0.032 | |
| stress activated mapk cascade | GO:0051403 | 93 | 0.032 | Human |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.032 | Human |
| cellular response to organic cyclic compound | GO:0071407 | 127 | 0.032 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.032 | Human |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.032 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 207 | 0.032 | |
| regulation of cytokine secretion involved in immune response | GO:0002739 | 7 | 0.032 | |
| neuron projection morphogenesis | GO:0048812 | 50 | 0.032 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.032 | Human |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.032 | Human |