| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 1.000 | Human |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 132 | 1.000 | Human |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 26 | 1.000 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 1.000 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 1.000 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 1.000 | |
| positive regulation of jnk cascade | GO:0046330 | 52 | 1.000 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 1.000 | Human |
| negative regulation of neurological system process | GO:0031645 | 2 | 0.999 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.998 | |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.997 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.997 | |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.996 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.996 | |
| positive regulation of tumor necrosis factor superfamily cytokine production | GO:1903557 | 22 | 0.995 | |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.993 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.992 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.991 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.989 | |
| positive regulation of tumor necrosis factor production | GO:0032760 | 21 | 0.989 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 60 | 0.985 | |
| regulation of jun kinase activity | GO:0043506 | 27 | 0.983 | |
| response to lipid | GO:0033993 | 206 | 0.982 | Human |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.979 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 62 | 0.977 | Human |
| positive regulation of map kinase activity | GO:0043406 | 80 | 0.976 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.974 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 81 | 0.972 | |
| positive regulation of cdc42 gtpase activity | GO:0043089 | 6 | 0.969 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.969 | |
| adaptive immune response | GO:0002250 | 49 | 0.968 | |
| cdc42 protein signal transduction | GO:0032488 | 4 | 0.966 | |
| peptidyl serine autophosphorylation | GO:0036289 | 2 | 0.964 | |
| negative regulation of myelination | GO:0031642 | 1 | 0.960 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.959 | |
| regulation of adaptive immune response | GO:0002819 | 33 | 0.958 | |
| cellular response to tumor necrosis factor | GO:0071356 | 63 | 0.952 | |
| neuronal action potential | GO:0019228 | 9 | 0.951 | |
| positive regulation of stress activated protein kinase signaling cascade | GO:0070304 | 61 | 0.948 | |
| positive regulation of jun kinase activity | GO:0043507 | 23 | 0.946 | |
| regulation of protein homodimerization activity | GO:0043496 | 9 | 0.946 | |
| immune response activating signal transduction | GO:0002757 | 90 | 0.943 | Human |
| osteoclast differentiation | GO:0030316 | 21 | 0.930 | Human |
| regulation of cdc42 protein signal transduction | GO:0032489 | 14 | 0.929 | |
| positive regulation of jak stat cascade | GO:0046427 | 35 | 0.925 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.924 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.923 | |
| programmed necrotic cell death | GO:0097300 | 18 | 0.922 | Mouse |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 119 | 0.922 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.910 | |
| regulation of stress activated protein kinase signaling cascade | GO:0070302 | 85 | 0.893 | |
| response to molecule of bacterial origin | GO:0002237 | 82 | 0.889 | Human |
| protein autoubiquitination | GO:0051865 | 37 | 0.887 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.882 | |
| hemopoiesis | GO:0030097 | 180 | 0.882 | Human |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 108 | 0.879 | |
| positive regulation of osteoclast differentiation | GO:0045672 | 9 | 0.877 | Human |
| myeloid cell differentiation | GO:0030099 | 117 | 0.876 | Human |
| positive regulation of t cell cytokine production | GO:0002726 | 4 | 0.874 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.850 | |
| transmission of nerve impulse | GO:0019226 | 11 | 0.846 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.845 | |
| response to cytokine | GO:0034097 | 232 | 0.841 | |
| regulation of jnk cascade | GO:0046328 | 73 | 0.840 | |
| positive regulation of protein kinase c signaling | GO:0090037 | 5 | 0.838 | |
| activation of nf kappab inducing kinase activity | GO:0007250 | 9 | 0.838 | |
| negative regulation of secretion by cell | GO:1903531 | 52 | 0.838 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.832 | |
| cellular response to biotic stimulus | GO:0071216 | 71 | 0.831 | Human |
| response to mechanical stimulus | GO:0009612 | 51 | 0.829 | |
| regulation of myelination | GO:0031641 | 1 | 0.829 | |
| positive regulation of defense response | GO:0031349 | 87 | 0.821 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.806 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.790 | |
| regulation of lymphocyte proliferation | GO:0050670 | 64 | 0.789 | |
| protein ubiquitination | GO:0016567 | 314 | 0.786 | |
| regulation of t cell cytokine production | GO:0002724 | 10 | 0.781 | |
| response to lipopolysaccharide | GO:0032496 | 70 | 0.779 | Human |
| toll like receptor 2 signaling pathway | GO:0034134 | 4 | 0.751 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.744 | |
| interleukin 2 production | GO:0032623 | 20 | 0.742 | |
| jnk cascade | GO:0007254 | 80 | 0.741 | |
| protein oligomerization | GO:0051259 | 173 | 0.740 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.739 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.738 | |
| regulation of stress activated mapk cascade | GO:0032872 | 84 | 0.727 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.719 | |
| positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002824 | 19 | 0.712 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.709 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.707 | Human |
| regulation of cytokine production | GO:0001817 | 232 | 0.697 | |
| protein k63 linked ubiquitination | GO:0070534 | 31 | 0.670 | |
| membrane protein ectodomain proteolysis | GO:0006509 | 33 | 0.662 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.654 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.652 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.639 | |
| negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001240 | 16 | 0.635 | |
| action potential | GO:0001508 | 34 | 0.635 | |
| protein catabolic process | GO:0030163 | 325 | 0.633 | Mouse |
| tnfsf11 mediated signaling pathway | GO:0071847 | 2 | 0.627 | |
| regulation of rho protein signal transduction | GO:0035023 | 79 | 0.623 | |
| immune system development | GO:0002520 | 195 | 0.616 | Human |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.614 | |
| cellular response to muramyl dipeptide | GO:0071225 | 3 | 0.603 | |
| regulation of osteoclast differentiation | GO:0045670 | 18 | 0.598 | Human |
| lymphocyte apoptotic process | GO:0070227 | 20 | 0.598 | |
| positive regulation of transcription regulatory region dna binding | GO:2000679 | 8 | 0.595 | Human |
| positive regulation of developmental process | GO:0051094 | 314 | 0.590 | Human |
| regulation of tyrosine phosphorylation of stat protein | GO:0042509 | 30 | 0.581 | |
| cytokine production involved in immune response | GO:0002367 | 27 | 0.578 | |
| regulation of map kinase activity | GO:0043405 | 108 | 0.575 | |
| positive regulation of interleukin 2 production | GO:0032743 | 11 | 0.565 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.564 | |
| regulation of protein kinase c signaling | GO:0090036 | 8 | 0.563 | |
| regulation of nik nf kappab signaling | GO:1901222 | 11 | 0.560 | |
| stress activated mapk cascade | GO:0051403 | 93 | 0.556 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.551 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.547 | |
| carbohydrate derivative transport | GO:1901264 | 20 | 0.545 | |
| gtp metabolic process | GO:0046039 | 239 | 0.542 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.538 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.537 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.535 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.535 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.532 | |
| cellular response to lipopolysaccharide | GO:0071222 | 57 | 0.523 | Human |
| positive regulation of nik nf kappab signaling | GO:1901224 | 10 | 0.521 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.512 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.507 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.503 | Human Mouse |
| regulation of transcription regulatory region dna binding | GO:2000677 | 15 | 0.495 | Human |
| stress activated protein kinase signaling cascade | GO:0031098 | 94 | 0.487 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.474 | Human |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.472 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.466 | |
| activation of innate immune response | GO:0002218 | 55 | 0.463 | |
| positive regulation of production of molecular mediator of immune response | GO:0002702 | 11 | 0.463 | |
| regulation of dna binding | GO:0051101 | 37 | 0.463 | Human |
| response to abiotic stimulus | GO:0009628 | 336 | 0.463 | |
| positive regulation of interleukin 8 biosynthetic process | GO:0045416 | 8 | 0.460 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.450 | |
| mapk cascade | GO:0000165 | 288 | 0.447 | |
| regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001239 | 20 | 0.445 | |
| positive regulation of protein homodimerization activity | GO:0090073 | 5 | 0.443 | |
| activation of protein kinase activity | GO:0032147 | 90 | 0.441 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.431 | Human |
| tumor necrosis factor production | GO:0032640 | 43 | 0.431 | |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 26 | 0.426 | |
| regulation of secretion | GO:0051046 | 194 | 0.424 | Mouse |
| myeloid leukocyte differentiation | GO:0002573 | 60 | 0.396 | Human |
| amine metabolic process | GO:0009308 | 44 | 0.391 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 52 | 0.388 | |
| protein secretion | GO:0009306 | 98 | 0.387 | Mouse |
| rho protein signal transduction | GO:0007266 | 26 | 0.384 | |
| response to other organism | GO:0051707 | 261 | 0.383 | Human |
| regulation of lymphocyte activation | GO:0051249 | 103 | 0.377 | |
| regulation of membrane potential | GO:0042391 | 95 | 0.373 | |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 51 | 0.371 | Human |
| regulation of protein binding | GO:0043393 | 66 | 0.368 | |
| t cell cytokine production | GO:0002369 | 12 | 0.358 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.358 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 50 | 0.356 | |
| myelination | GO:0042552 | 6 | 0.348 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.347 | Human |
| defense response to bacterium | GO:0042742 | 63 | 0.341 | |
| regulation of neurological system process | GO:0031644 | 6 | 0.340 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.336 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.333 | |
| positive regulation of endothelial cell apoptotic process | GO:2000353 | 8 | 0.328 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.319 | Human |
| response to virus | GO:0009615 | 126 | 0.315 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.307 | |
| trail activated apoptotic signaling pathway | GO:0036462 | 4 | 0.303 | |
| tumor necrosis factor mediated signaling pathway | GO:0033209 | 27 | 0.294 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 25 | 0.293 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.291 | |
| positive regulation of membrane protein ectodomain proteolysis | GO:0051044 | 13 | 0.288 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.283 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.279 | |
| immune response | GO:0006955 | 307 | 0.277 | |
| positive regulation of cytokine secretion involved in immune response | GO:0002741 | 2 | 0.276 | |
| translation | GO:0006412 | 132 | 0.274 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.271 | |
| positive regulation of tyrosine phosphorylation of stat protein | GO:0042531 | 28 | 0.265 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.258 | |
| neurological system process | GO:0050877 | 163 | 0.258 | |
| regulation of cytokine production involved in immune response | GO:0002718 | 22 | 0.256 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.244 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.244 | Human Mouse |
| cytokine biosynthetic process | GO:0042089 | 37 | 0.240 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.237 | |
| regulation of immune response | GO:0050776 | 201 | 0.235 | |
| negative regulation of nervous system development | GO:0051961 | 28 | 0.232 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.231 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.231 | |
| regulation of tor signaling | GO:0032006 | 30 | 0.231 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.228 | |
| positive regulation of dna binding | GO:0043388 | 17 | 0.226 | Human |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.221 | |
| regulation of interferon beta production | GO:0032648 | 22 | 0.221 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.220 | |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 25 | 0.220 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.217 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.214 | Human |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.209 | |
| positive regulation of interleukin 8 production | GO:0032757 | 36 | 0.206 | |
| regulation of innate immune response | GO:0045088 | 97 | 0.205 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.205 | |
| cytokine production | GO:0001816 | 247 | 0.202 | |
| necroptotic signaling pathway | GO:0097527 | 6 | 0.201 | |
| response to interleukin 1 | GO:0070555 | 47 | 0.193 | Human |
| immune response regulating signaling pathway | GO:0002764 | 97 | 0.192 | Human |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 85 | 0.191 | |
| positive regulation of lymphocyte mediated immunity | GO:0002708 | 23 | 0.190 | |
| serine phosphorylation of stat protein | GO:0042501 | 4 | 0.187 | |
| membrane protein proteolysis | GO:0033619 | 38 | 0.187 | |
| positive regulation of immune effector process | GO:0002699 | 40 | 0.185 | |
| positive regulation of hair follicle development | GO:0051798 | 3 | 0.183 | |
| cellular response to lipid | GO:0071396 | 127 | 0.182 | Human |
| regulation of ion transmembrane transport | GO:0034765 | 132 | 0.180 | |
| regulation of immune effector process | GO:0002697 | 91 | 0.177 | |
| regulation of anion transport | GO:0044070 | 25 | 0.177 | |
| regulation of jak stat cascade | GO:0046425 | 44 | 0.175 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.174 | |
| immunoglobulin secretion | GO:0048305 | 1 | 0.174 | Mouse |
| positive regulation of erk1 and erk2 cascade via tnfsf11 mediated signaling | GO:0071848 | 2 | 0.173 | |
| regulation of tumor necrosis factor production | GO:0032680 | 43 | 0.169 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.166 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.165 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.165 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.163 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.162 | |
| positive regulation of secretion by cell | GO:1903532 | 108 | 0.160 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.160 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.159 | |
| positive regulation of adaptive immune response | GO:0002821 | 21 | 0.149 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.148 | |
| positive regulation of cell activation | GO:0050867 | 81 | 0.146 | |
| regulation of protein localization | GO:0032880 | 296 | 0.145 | Mouse |
| regulation of protein transport | GO:0051223 | 213 | 0.144 | Mouse |
| multicellular organismal signaling | GO:0035637 | 34 | 0.143 | |
| jak stat cascade | GO:0007259 | 46 | 0.140 | |
| generation of neurons | GO:0048699 | 152 | 0.140 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.139 | |
| interleukin 6 production | GO:0032635 | 37 | 0.135 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.134 | |
| negative regulation of response to external stimulus | GO:0032102 | 83 | 0.133 | |
| regulation of defense response | GO:0031347 | 154 | 0.129 | |
| positive regulation of t cell mediated immunity | GO:0002711 | 12 | 0.128 | |
| innate immune response | GO:0045087 | 178 | 0.123 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 35 | 0.123 | |
| endocytic recycling | GO:0032456 | 12 | 0.123 | |
| protein homooligomerization | GO:0051260 | 100 | 0.122 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.117 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.117 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 75 | 0.116 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.115 | |
| cellular response to mechanical stimulus | GO:0071260 | 39 | 0.115 | |
| cellular response to hyperoxia | GO:0071455 | 4 | 0.114 | |
| ripoptosome assembly | GO:0097343 | 1 | 0.113 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.113 | |
| positive regulation of binding | GO:0051099 | 45 | 0.113 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.112 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.111 | |
| secretion by cell | GO:0032940 | 226 | 0.110 | Mouse |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 22 | 0.110 | |
| positive regulation of interleukin 6 production | GO:0032755 | 21 | 0.108 | |
| positive regulation of rho gtpase activity | GO:0032321 | 56 | 0.108 | |
| endosomal transport | GO:0016197 | 129 | 0.107 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 40 | 0.106 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.105 | |
| leukocyte differentiation | GO:0002521 | 98 | 0.105 | Human |
| regulation of t cell proliferation | GO:0042129 | 42 | 0.105 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.104 | |
| endothelial cell apoptotic process | GO:0072577 | 26 | 0.104 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.101 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 38 | 0.098 | |
| regulation of binding | GO:0051098 | 111 | 0.098 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.098 | |
| cellular component disassembly | GO:0022411 | 92 | 0.097 | |
| positive regulation of ras gtpase activity | GO:0032320 | 117 | 0.096 | |
| response to bacterium | GO:0009617 | 144 | 0.096 | Human |
| negative regulation of defense response | GO:0031348 | 47 | 0.093 | |
| neurogenesis | GO:0022008 | 169 | 0.092 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.092 | |
| protein k48 linked ubiquitination | GO:0070936 | 38 | 0.090 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.089 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.088 | |
| protein localization to organelle | GO:0033365 | 280 | 0.087 | |
| mononuclear cell proliferation | GO:0032943 | 71 | 0.086 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.086 | |
| positive regulation of interferon beta production | GO:0032728 | 17 | 0.084 | |
| positive regulation of intracellular protein transport | GO:0090316 | 76 | 0.083 | |
| regulation of lymphocyte mediated immunity | GO:0002706 | 33 | 0.083 | |
| nervous system development | GO:0007399 | 293 | 0.083 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 156 | 0.082 | |
| cellular homeostasis | GO:0019725 | 196 | 0.082 | |
| protein processing | GO:0016485 | 226 | 0.082 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.081 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 49 | 0.081 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.081 | |
| regulation of rho gtpase activity | GO:0032319 | 66 | 0.080 | |
| regulation of endothelial cell apoptotic process | GO:2000351 | 24 | 0.080 | |
| gtp catabolic process | GO:0006184 | 237 | 0.080 | |
| intracellular protein transport | GO:0006886 | 270 | 0.079 | |
| tyrosine phosphorylation of stat protein | GO:0007260 | 33 | 0.078 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 29 | 0.078 | |
| response to alcohol | GO:0097305 | 64 | 0.078 | |
| regulation of protein monoubiquitination | GO:1902525 | 1 | 0.076 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.075 | |
| protein targeting | GO:0006605 | 187 | 0.074 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.073 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.073 | |
| protein kinase c signaling | GO:0070528 | 17 | 0.073 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.072 | |
| interferon beta production | GO:0032608 | 23 | 0.071 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.070 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.069 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.069 | |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 61 | 0.068 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.067 | |
| regulation of protein localization to nucleus | GO:1900180 | 85 | 0.067 | |
| mitochondrion organization | GO:0007005 | 156 | 0.067 | |
| neuron remodeling | GO:0016322 | 2 | 0.065 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.064 | |
| regulation of ras gtpase activity | GO:0032318 | 128 | 0.064 | |
| peptidyl serine modification | GO:0018209 | 106 | 0.063 | |
| regulation of cdc42 gtpase activity | GO:0043088 | 10 | 0.063 | |
| cell cycle g1 s phase transition | GO:0044843 | 80 | 0.061 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.060 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 88 | 0.060 | |
| regulation of response to wounding | GO:1903034 | 101 | 0.060 | |
| ensheathment of neurons | GO:0007272 | 6 | 0.059 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.059 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.059 | |
| positive regulation of leukocyte mediated immunity | GO:0002705 | 24 | 0.057 | |
| regulation of type i interferon production | GO:0032479 | 26 | 0.057 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.057 | |
| negative regulation of alpha beta t cell proliferation | GO:0046642 | 1 | 0.056 | |
| activation of immune response | GO:0002253 | 114 | 0.056 | Human |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 45 | 0.055 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.055 | |
| regulation of interleukin 6 production | GO:0032675 | 37 | 0.054 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.053 | |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.053 | Human |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.053 | |
| positive regulation of cytokine production involved in immune response | GO:0002720 | 6 | 0.053 | |
| negative regulation of multi organism process | GO:0043901 | 92 | 0.052 | |
| regulation of oxidoreductase activity | GO:0051341 | 43 | 0.052 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.051 | |
| cation homeostasis | GO:0055080 | 189 | 0.051 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.051 | |
| response to steroid hormone | GO:0048545 | 80 | 0.051 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.050 | Human |
| defense response to gram positive bacterium | GO:0050830 | 29 | 0.050 | |
| cytokine metabolic process | GO:0042107 | 38 | 0.049 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.049 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.048 | |
| response to growth factor | GO:0070848 | 205 | 0.047 | |
| protein heterooligomerization | GO:0051291 | 16 | 0.047 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 3 | 0.047 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.046 | |
| fat soluble vitamin metabolic process | GO:0006775 | 19 | 0.046 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 48 | 0.045 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.045 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 99 | 0.045 | |
| protein monoubiquitination | GO:0006513 | 39 | 0.045 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.044 | |
| nucleobase containing compound transport | GO:0015931 | 51 | 0.044 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 39 | 0.044 | Human |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.044 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.043 | |
| regulation of membrane protein ectodomain proteolysis | GO:0051043 | 17 | 0.043 | |
| tor signaling | GO:0031929 | 39 | 0.043 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.043 | |
| necrotic cell death | GO:0070265 | 21 | 0.042 | Mouse |
| regulation of transmembrane transporter activity | GO:0022898 | 74 | 0.042 | |
| positive regulation of interferon alpha production | GO:0032727 | 11 | 0.042 | |
| chemokine production | GO:0032602 | 32 | 0.041 | |
| positive regulation of cell size | GO:0045793 | 3 | 0.041 | |
| antigen receptor mediated signaling pathway | GO:0050851 | 38 | 0.041 | Human |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.041 | |
| response to acid chemical | GO:0001101 | 66 | 0.041 | |
| amyloid fibril formation | GO:1990000 | 3 | 0.041 | |
| negative regulation of interleukin 6 production | GO:0032715 | 13 | 0.040 | |
| positive regulation of tor signaling | GO:0032008 | 11 | 0.040 | |
| defense response to other organism | GO:0098542 | 129 | 0.040 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.040 | |
| defense response | GO:0006952 | 315 | 0.040 | |
| positive regulation of necroptotic process | GO:0060545 | 2 | 0.039 | |
| viral process | GO:0016032 | 146 | 0.039 | |
| type i interferon production | GO:0032606 | 27 | 0.039 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.038 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.038 | |
| positive regulation of protein linear polyubiquitination | GO:1902530 | 2 | 0.038 | |
| extrinsic apoptotic signaling pathway via death domain receptors | GO:0008625 | 42 | 0.038 | |
| regulation of immunoglobulin production | GO:0002637 | 4 | 0.038 | Mouse |
| positive regulation of lymphocyte migration | GO:2000403 | 16 | 0.038 | |
| canonical wnt signaling pathway | GO:0060070 | 116 | 0.038 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 37 | 0.038 | Human |
| positive regulation of secretion | GO:0051047 | 116 | 0.038 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.037 | Mouse |
| regulation of tyrosine phosphorylation of stat1 protein | GO:0042510 | 11 | 0.037 | |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 44 | 0.036 | |
| anion transport | GO:0006820 | 161 | 0.036 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.036 | Mouse |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.036 | |
| regulation of nucleoside transport | GO:0032242 | 1 | 0.035 | |
| positive regulation of peptidyl serine phosphorylation | GO:0033138 | 42 | 0.035 | |
| regulation of leukocyte apoptotic process | GO:2000106 | 25 | 0.035 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.035 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.035 | |
| positive regulation of transport | GO:0051050 | 336 | 0.034 | |
| positive regulation of immune response | GO:0050778 | 159 | 0.033 | |
| t helper 1 cell differentiation | GO:0045063 | 1 | 0.033 | |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.033 | |
| response to hyperoxia | GO:0055093 | 4 | 0.033 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.033 | |
| regulation of lymphocyte apoptotic process | GO:0070228 | 15 | 0.033 | |
| positive regulation of protein secretion | GO:0050714 | 60 | 0.033 | |
| single organism nuclear import | GO:1902593 | 104 | 0.033 | |
| positive regulation of protein polyubiquitination | GO:1902916 | 3 | 0.033 | |
| nuclear transport | GO:0051169 | 179 | 0.033 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.033 | |
| chemical homeostasis | GO:0048878 | 306 | 0.032 | |
| locomotory behavior | GO:0007626 | 1 | 0.032 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.032 | |
| t cell mediated immunity | GO:0002456 | 25 | 0.032 | |
| protein homotrimerization | GO:0070207 | 9 | 0.032 | |
| neuron development | GO:0048666 | 113 | 0.032 | |
| post embryonic development | GO:0009791 | 2 | 0.032 | |
| regulation of hair cycle | GO:0042634 | 10 | 0.032 | |
| negative regulation of alpha beta t cell activation | GO:0046636 | 3 | 0.031 | |
| growth | GO:0040007 | 202 | 0.031 | |
| chemokine metabolic process | GO:0050755 | 4 | 0.031 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.031 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.031 | |
| regulation of system process | GO:0044057 | 101 | 0.031 | |
| activation of jnkk activity | GO:0007256 | 1 | 0.031 | |
| cellular response to oxygen levels | GO:0071453 | 55 | 0.031 | |
| inflammatory response | GO:0006954 | 79 | 0.031 | |
| single organism cellular localization | GO:1902580 | 332 | 0.031 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 51 | 0.030 | Human |
| dephosphorylation | GO:0016311 | 209 | 0.030 | |
| cellular calcium ion homeostasis | GO:0006874 | 117 | 0.030 | |
| positive regulation of tumor necrosis factor biosynthetic process | GO:0042535 | 5 | 0.030 | |
| cell division | GO:0051301 | 168 | 0.030 | |
| lipid metabolic process | GO:0006629 | 381 | 0.030 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 125 | 0.029 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.029 | |
| regulation of synaptic plasticity | GO:0048167 | 3 | 0.029 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.029 | |
| fibril organization | GO:0097435 | 10 | 0.028 | |
| syncytium formation by plasma membrane fusion | GO:0000768 | 2 | 0.028 | |
| release of cytoplasmic sequestered nf kappab | GO:0008588 | 4 | 0.028 | |
| positive regulation of rac gtpase activity | GO:0032855 | 31 | 0.027 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.027 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.027 | |
| production of molecular mediator of immune response | GO:0002440 | 37 | 0.027 | |
| taxis | GO:0042330 | 157 | 0.026 | |
| regulation of isotype switching | GO:0045191 | 2 | 0.026 | |
| protein targeting to nucleus | GO:0044744 | 104 | 0.026 | |
| positive regulation of immunoglobulin production | GO:0002639 | 4 | 0.026 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.026 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.026 | |
| cell growth | GO:0016049 | 160 | 0.026 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.025 | |
| neuron differentiation | GO:0030182 | 138 | 0.025 | |
| actin filament based process | GO:0030029 | 224 | 0.025 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.025 | |
| cellular response to increased oxygen levels | GO:0036295 | 4 | 0.025 | |
| regulation of chemokine production | GO:0032642 | 31 | 0.025 | |
| lymphocyte proliferation | GO:0046651 | 70 | 0.024 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.024 | |
| cell morphogenesis | GO:0000902 | 296 | 0.024 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.024 | |
| positive regulation of chemokine production | GO:0032722 | 22 | 0.024 | |
| interferon alpha production | GO:0032607 | 11 | 0.024 | |
| regulation of cell activation | GO:0050865 | 125 | 0.023 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 156 | 0.023 | |
| axon ensheathment | GO:0008366 | 6 | 0.023 | |
| regulation of protein secretion | GO:0050708 | 86 | 0.023 | Mouse |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.023 | |
| somatic recombination of immunoglobulin gene segments | GO:0016447 | 4 | 0.023 | |
| positive regulation of myeloid leukocyte differentiation | GO:0002763 | 24 | 0.023 | Human |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.022 | Mouse |
| regulation of protein linear polyubiquitination | GO:1902528 | 2 | 0.022 | |
| regulation of phosphatase activity | GO:0010921 | 81 | 0.022 | |
| multi organism cellular process | GO:0044764 | 156 | 0.022 | |
| positive regulation of type i interferon mediated signaling pathway | GO:0060340 | 4 | 0.022 | |
