| protein ubiquitination | GO:0016567 | 314 | 1.000 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 1.000 | |
| histone h2a ubiquitination | GO:0033522 | 17 | 1.000 | |
| chromatin organization | GO:0006325 | 351 | 1.000 | Fly |
| histone ubiquitination | GO:0016574 | 31 | 1.000 | |
| histone monoubiquitination | GO:0010390 | 20 | 1.000 | |
| chromatin modification | GO:0016568 | 298 | 1.000 | Fly |
| histone h2a monoubiquitination | GO:0035518 | 11 | 0.998 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.998 | |
| histone modification | GO:0016570 | 251 | 0.995 | Fly |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.995 | |
| protein monoubiquitination | GO:0006513 | 39 | 0.994 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.993 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.993 | |
| segmentation | GO:0035282 | 4 | 0.983 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.978 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.976 | |
| protein catabolic process | GO:0030163 | 325 | 0.976 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.968 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.964 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.963 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.959 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.951 | Fly |
| negative regulation of cell death | GO:0060548 | 345 | 0.941 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.935 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.918 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.909 | |
| response to radiation | GO:0009314 | 151 | 0.896 | |
| fibroblast proliferation | GO:0048144 | 33 | 0.895 | |
| blastoderm segmentation | GO:0007350 | 2 | 0.892 | |
| gene silencing | GO:0016458 | 49 | 0.888 | Fly |
| mrna metabolic process | GO:0016071 | 175 | 0.881 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.877 | |
| response to endoplasmic reticulum stress | GO:0034976 | 49 | 0.867 | |
| rostrocaudal neural tube patterning | GO:0021903 | 1 | 0.851 | |
| regulation of chromosome organization | GO:0033044 | 103 | 0.844 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.836 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.821 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.816 | |
| negative regulation of intrinsic apoptotic signaling pathway | GO:2001243 | 40 | 0.791 | |
| dna repair | GO:0006281 | 198 | 0.779 | |
| embryo development | GO:0009790 | 123 | 0.773 | Worm |
| cell development | GO:0048468 | 328 | 0.768 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.768 | Rat |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 76 | 0.759 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.758 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.754 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.747 | |
| negative regulation of chromosome organization | GO:2001251 | 48 | 0.731 | |
| negative regulation of g1 s transition of mitotic cell cycle | GO:2000134 | 29 | 0.728 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 37 | 0.727 | |
| response to gamma radiation | GO:0010332 | 14 | 0.703 | |
| anterior posterior axis specification | GO:0009948 | 2 | 0.696 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.660 | |
| bmp signaling pathway | GO:0030509 | 49 | 0.644 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.633 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.609 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.592 | |
| regulation of nervous system development | GO:0051960 | 88 | 0.591 | |
| internal peptidyl lysine acetylation | GO:0018393 | 97 | 0.589 | |
| macromolecule methylation | GO:0043414 | 97 | 0.576 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.564 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.555 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.552 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.548 | |
| protein deubiquitination | GO:0016579 | 79 | 0.545 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.541 | |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 61 | 0.527 | |
| chemotaxis | GO:0006935 | 157 | 0.514 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.505 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.490 | |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.475 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 71 | 0.474 | |
| rna processing | GO:0006396 | 255 | 0.467 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.461 | |
| response to ionizing radiation | GO:0010212 | 65 | 0.436 | |
| pattern specification process | GO:0007389 | 43 | 0.403 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.400 | |
| protein localization to organelle | GO:0033365 | 280 | 0.400 | |
| intracellular receptor signaling pathway | GO:0030522 | 104 | 0.399 | |
| response to growth factor | GO:0070848 | 205 | 0.395 | |
| positive regulation of ligase activity | GO:0051351 | 19 | 0.390 | |
| cellular response to decreased oxygen levels | GO:0036294 | 51 | 0.389 | |
| mrna splicing via spliceosome | GO:0000398 | 89 | 0.388 | |
| signal transduction by p53 class mediator | GO:0072331 | 72 | 0.384 | |
| organelle fission | GO:0048285 | 149 | 0.382 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.373 | |
| regulation of protein stability | GO:0031647 | 87 | 0.371 | Rat |
| regionalization | GO:0003002 | 29 | 0.361 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 37 | 0.360 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 89 | 0.358 | |
| tube development | GO:0035295 | 125 | 0.356 | |
| rna splicing via transesterification reactions | GO:0000375 | 90 | 0.349 | |
| organ morphogenesis | GO:0009887 | 147 | 0.334 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.314 | |
| axonogenesis | GO:0007409 | 31 | 0.297 | |
| oocyte differentiation | GO:0009994 | 2 | 0.295 | |
| neurogenesis | GO:0022008 | 169 | 0.293 | |
| chromosome segregation | GO:0007059 | 114 | 0.290 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.274 | |
| cellular response to oxygen levels | GO:0071453 | 55 | 0.271 | |
| post embryonic development | GO:0009791 | 2 | 0.261 | Worm |
| neuron projection development | GO:0031175 | 106 | 0.258 | |
| generation of neurons | GO:0048699 | 152 | 0.257 | |
| cellular response to hypoxia | GO:0071456 | 51 | 0.254 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.245 | |
| internal protein amino acid acetylation | GO:0006475 | 101 | 0.244 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 94 | 0.240 | |
| growth | GO:0040007 | 202 | 0.238 | Worm |
| positive regulation of protein ubiquitination | GO:0031398 | 53 | 0.237 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.232 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 87 | 0.224 | |
| regulation of cell cycle arrest | GO:0071156 | 36 | 0.222 | |
| nervous system development | GO:0007399 | 293 | 0.222 | |
| response to caffeine | GO:0031000 | 3 | 0.221 | |
| protein alkylation | GO:0008213 | 74 | 0.215 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.214 | |
| protein targeting | GO:0006605 | 187 | 0.208 | |
| intracellular protein transport | GO:0006886 | 270 | 0.205 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.204 | |
| skeletal system development | GO:0001501 | 79 | 0.204 | |
| protein acylation | GO:0043543 | 138 | 0.204 | |
| taxis | GO:0042330 | 157 | 0.197 | |
| response to lipid | GO:0033993 | 206 | 0.194 | |
| female gamete generation | GO:0007292 | 2 | 0.192 | |
| spinal cord development | GO:0021510 | 4 | 0.191 | |
| neural tube patterning | GO:0021532 | 2 | 0.189 | |
| nuclear transport | GO:0051169 | 179 | 0.189 | |
| regulation of leukocyte proliferation | GO:0070663 | 67 | 0.187 | |
| positive regulation of proteasomal protein catabolic process | GO:1901800 | 35 | 0.185 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.185 | |
| neuron development | GO:0048666 | 113 | 0.180 | |
| regulation of histone modification | GO:0031056 | 47 | 0.174 | |
| negative regulation of response to dna damage stimulus | GO:2001021 | 33 | 0.174 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.173 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.172 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.168 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.168 | |
| embryonic organ morphogenesis | GO:0048562 | 24 | 0.165 | |
| single organism nuclear import | GO:1902593 | 104 | 0.164 | |
| rna splicing | GO:0008380 | 131 | 0.163 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.163 | |
| response to transforming growth factor beta | GO:0071559 | 94 | 0.161 | |
| methylation | GO:0032259 | 106 | 0.160 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.158 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.158 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.157 | |
| cellular response to unfolded protein | GO:0034620 | 16 | 0.157 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.152 | |
| positive regulation of ubiquitin protein transferase activity | GO:0051443 | 18 | 0.151 | |
| mrna processing | GO:0006397 | 133 | 0.151 | |
| neuron differentiation | GO:0030182 | 138 | 0.151 | |
| cartilage development | GO:0051216 | 31 | 0.148 | |
| regulation of organ morphogenesis | GO:2000027 | 24 | 0.147 | |
| regulation of signal transduction by p53 class mediator | GO:1901796 | 26 | 0.147 | |
| regulation of neuron differentiation | GO:0045664 | 70 | 0.146 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.145 | |
| regulation of fibroblast proliferation | GO:0048145 | 32 | 0.143 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.142 | |
| histone methylation | GO:0016571 | 60 | 0.141 | |
| response to oxygen levels | GO:0070482 | 100 | 0.139 | |
| leukocyte proliferation | GO:0070661 | 74 | 0.135 | |
| response to hypoxia | GO:0001666 | 96 | 0.135 | |
| regulation of protein targeting | GO:1903533 | 91 | 0.134 | |
| negative regulation of protein ubiquitination | GO:0031397 | 35 | 0.134 | |
| locomotory behavior | GO:0007626 | 1 | 0.132 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.129 | |
| chromatin silencing | GO:0006342 | 12 | 0.128 | Fly |
| metencephalon development | GO:0022037 | 2 | 0.127 | |
| cerebellum development | GO:0021549 | 2 | 0.125 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.125 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.125 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.124 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 81 | 0.123 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.121 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.121 | |
| regulation of ligase activity | GO:0051340 | 29 | 0.120 | |
| negative regulation of cell cycle g1 s phase transition | GO:1902807 | 29 | 0.118 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.116 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.115 | |
| protein import | GO:0017038 | 130 | 0.115 | |
| embryonic morphogenesis | GO:0048598 | 85 | 0.114 | |
| forebrain development | GO:0030900 | 26 | 0.113 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.111 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.111 | |
| chemical homeostasis | GO:0048878 | 306 | 0.110 | |
| response to topologically incorrect protein | GO:0035966 | 29 | 0.108 | |
| regulation of b cell activation | GO:0050864 | 24 | 0.107 | |
| regulation of cell cycle g1 s phase transition | GO:1902806 | 42 | 0.106 | |
| regeneration | GO:0031099 | 4 | 0.106 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.106 | |
| signal transduction involved in mitotic cell cycle checkpoint | GO:0072413 | 13 | 0.106 | |
| limbic system development | GO:0021761 | 3 | 0.105 | |
| g1 dna damage checkpoint | GO:0044783 | 18 | 0.101 | |
| axon guidance | GO:0007411 | 12 | 0.101 | |
| negative regulation of histone modification | GO:0031057 | 19 | 0.100 | |
| regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:2000058 | 7 | 0.100 | |
| energy homeostasis | GO:0097009 | 3 | 0.098 | |
| peptidyl lysine acetylation | GO:0018394 | 101 | 0.098 | |
| eye morphogenesis | GO:0048592 | 16 | 0.097 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.097 | |
| negative regulation of dna metabolic process | GO:0051053 | 57 | 0.097 | |
| negative regulation of chromatin modification | GO:1903309 | 21 | 0.096 | |
| response to drug | GO:0042493 | 81 | 0.096 | |
| response to oxidative stress | GO:0006979 | 121 | 0.096 | |
| negative regulation of transcription involved in g1 s transition of mitotic cell cycle | GO:0071930 | 2 | 0.096 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.095 | |
| cell growth | GO:0016049 | 160 | 0.094 | |
| mitotic g1 s transition checkpoint | GO:0044819 | 17 | 0.093 | |
| single organism cellular localization | GO:1902580 | 332 | 0.092 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.092 | |
| response to unfolded protein | GO:0006986 | 24 | 0.089 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 98 | 0.088 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.088 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.088 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.087 | |
| protein oligomerization | GO:0051259 | 173 | 0.087 | |
| regulation of translation | GO:0006417 | 89 | 0.087 | |
| heart development | GO:0007507 | 95 | 0.087 | |
| regulation of mitotic metaphase anaphase transition | GO:0030071 | 26 | 0.086 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.085 | |
| cell division | GO:0051301 | 168 | 0.085 | |
| response to alcohol | GO:0097305 | 64 | 0.083 | |
| regulation of symbiosis encompassing mutualism through parasitism | GO:0043903 | 109 | 0.083 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 31 | 0.083 | |
| regulation of g1 s transition of mitotic cell cycle | GO:2000045 | 40 | 0.082 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.082 | |
| chondrocyte development | GO:0002063 | 1 | 0.082 | |
| protein stabilization | GO:0050821 | 64 | 0.081 | |
| histone acetylation | GO:0016573 | 93 | 0.081 | |
| cellular response to topologically incorrect protein | GO:0035967 | 19 | 0.079 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.079 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.078 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.077 | |
| establishment or maintenance of monopolar cell polarity | GO:0061339 | 1 | 0.077 | |
| regulation of mononuclear cell proliferation | GO:0032944 | 65 | 0.075 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.074 | |
| developmental cell growth | GO:0048588 | 18 | 0.071 | |
| peptidyl lysine modification | GO:0018205 | 144 | 0.071 | |
| neuron projection morphogenesis | GO:0048812 | 50 | 0.071 | |
| signal transduction involved in dna damage checkpoint | GO:0072422 | 15 | 0.071 | |
| regulation of chromatin modification | GO:1903308 | 51 | 0.070 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.070 | |
| positive regulation of cell cycle arrest | GO:0071158 | 23 | 0.070 | |
| response to acid chemical | GO:0001101 | 66 | 0.070 | |
| negative regulation of translation | GO:0017148 | 37 | 0.069 | |
| metal ion transport | GO:0030001 | 272 | 0.067 | |
| protein k63 linked ubiquitination | GO:0070534 | 31 | 0.066 | |
| negative regulation of protein catabolic process | GO:0042177 | 59 | 0.066 | |
| negative regulation of signal transduction by p53 class mediator | GO:1901797 | 15 | 0.066 | |
| urogenital system development | GO:0001655 | 65 | 0.065 | |
| autophagy | GO:0006914 | 88 | 0.064 | |
| dna replication | GO:0006260 | 116 | 0.063 | |
| regulation of axon guidance | GO:1902667 | 3 | 0.062 | |
| response to temperature stimulus | GO:0009266 | 22 | 0.062 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.062 | |
| response to retinoic acid | GO:0032526 | 33 | 0.062 | |
| maintenance of location | GO:0051235 | 112 | 0.061 | |
| protein processing | GO:0016485 | 226 | 0.061 | |
| regulation of ubiquitin protein transferase activity | GO:0051438 | 28 | 0.060 | |
| ribonucleoprotein complex biogenesis | GO:0022613 | 116 | 0.060 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.060 | |
| axis specification | GO:0009798 | 12 | 0.060 | |
| oocyte development | GO:0048599 | 1 | 0.060 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.059 | |
| protein targeting to nucleus | GO:0044744 | 104 | 0.059 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 35 | 0.059 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 37 | 0.059 | |
| regulation of chromatin organization | GO:1902275 | 56 | 0.058 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.058 | |
| response to inorganic substance | GO:0010035 | 127 | 0.058 | |
| response to wounding | GO:0009611 | 168 | 0.058 | |
| immune response | GO:0006955 | 307 | 0.058 | |
| cation transport | GO:0006812 | 331 | 0.057 | |
| viral process | GO:0016032 | 146 | 0.057 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.057 | |
| mitotic dna damage checkpoint | GO:0044773 | 28 | 0.056 | |
| mitochondrion organization | GO:0007005 | 156 | 0.056 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 78 | 0.055 | |
| cellular homeostasis | GO:0019725 | 196 | 0.055 | |
| ion homeostasis | GO:0050801 | 230 | 0.055 | |
| axon development | GO:0061564 | 34 | 0.055 | |
| response to estrogen | GO:0043627 | 47 | 0.055 | |
| regulation of protein processing | GO:0070613 | 150 | 0.054 | |
| regulation of cell development | GO:0060284 | 161 | 0.054 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.053 | |
| reproductive process | GO:0022414 | 106 | 0.053 | |
| regulation of viral process | GO:0050792 | 103 | 0.053 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.052 | |
| g0 to g1 transition | GO:0045023 | 3 | 0.052 | |
| primary neural tube formation | GO:0014020 | 3 | 0.052 | |
| adult locomotory behavior | GO:0008344 | 1 | 0.052 | |
| zymogen activation | GO:0031638 | 70 | 0.051 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.051 | |
| response to toxic substance | GO:0009636 | 37 | 0.051 | |
| positive regulation of intracellular protein transport | GO:0090316 | 76 | 0.050 | |
| transcription factor import into nucleus | GO:0042991 | 40 | 0.050 | |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.049 | |
| negative regulation of calcium ion import | GO:0090281 | 1 | 0.049 | |
| protein n linked glycosylation via asparagine | GO:0018279 | 10 | 0.048 | |
| positive regulation of protein complex assembly | GO:0031334 | 86 | 0.048 | |
| establishment of monopolar cell polarity | GO:0061162 | 1 | 0.048 | |
| regulation of mrna stability | GO:0043488 | 23 | 0.048 | |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.048 | |
| ribosome biogenesis | GO:0042254 | 48 | 0.047 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.047 | |
| negative regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043154 | 46 | 0.046 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 60 | 0.046 | |
| sex differentiation | GO:0007548 | 45 | 0.046 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 22 | 0.046 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.046 | |
| regulation of nuclear division | GO:0051783 | 65 | 0.045 | |
| golgi vesicle transport | GO:0048193 | 80 | 0.045 | |
| hormone metabolic process | GO:0042445 | 61 | 0.045 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.045 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 16 | 0.045 | |
| development of primary sexual characteristics | GO:0045137 | 35 | 0.044 | |
| multicellular organismal homeostasis | GO:0048871 | 67 | 0.044 | |
| modification by host of symbiont morphology or physiology | GO:0051851 | 26 | 0.043 | |
| mating | GO:0007618 | 1 | 0.043 | |
| protein modification by small protein removal | GO:0070646 | 92 | 0.042 | |
| negative regulation of viral process | GO:0048525 | 66 | 0.042 | |
| activation of immune response | GO:0002253 | 114 | 0.042 | |
| protein methylation | GO:0006479 | 74 | 0.042 | |
| regulation of tooth mineralization | GO:0070170 | 3 | 0.042 | |
| histone h3 acetylation | GO:0043966 | 45 | 0.041 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 39 | 0.041 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 30 | 0.041 | |
| hindbrain development | GO:0030902 | 3 | 0.041 | |
| double strand break repair | GO:0006302 | 101 | 0.040 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.040 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.038 | |
| regulation of odontogenesis | GO:0042481 | 4 | 0.038 | |
| protein import into nucleus | GO:0006606 | 104 | 0.038 | |
| mitotic g1 dna damage checkpoint | GO:0031571 | 17 | 0.038 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.037 | |
| oogenesis | GO:0048477 | 2 | 0.037 | |
| regulation of metaphase anaphase transition of cell cycle | GO:1902099 | 26 | 0.037 | |
| cell morphogenesis involved in neuron differentiation | GO:0048667 | 44 | 0.037 | |
| embryonic cranial skeleton morphogenesis | GO:0048701 | 6 | 0.037 | |
| negative regulation of protein modification by small protein conjugation or removal | GO:1903321 | 41 | 0.036 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 116 | 0.036 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.036 | |
| multi organism reproductive process | GO:0044703 | 54 | 0.036 | |
| developmental programmed cell death | GO:0010623 | 3 | 0.036 | |
| response to fungus | GO:0009620 | 4 | 0.035 | |
| gland development | GO:0048732 | 48 | 0.035 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.035 | |
| positive regulation of protein import into nucleus | GO:0042307 | 46 | 0.034 | |
| maintenance of protein location | GO:0045185 | 57 | 0.034 | |
| biomineral tissue development | GO:0031214 | 39 | 0.034 | |
| regulation of dna repair | GO:0006282 | 47 | 0.033 | |
| ribonucleoprotein complex assembly | GO:0022618 | 78 | 0.033 | |
| smad protein import into nucleus | GO:0007184 | 13 | 0.033 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.033 | |
| dna integrity checkpoint | GO:0031570 | 71 | 0.032 | |
| negative regulation of cysteine type endopeptidase activity | GO:2000117 | 48 | 0.032 | |
| monovalent inorganic cation transport | GO:0015672 | 128 | 0.032 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.032 | |
| regulation of mrna splicing via spliceosome | GO:0048024 | 32 | 0.032 | |
| behavior | GO:0007610 | 112 | 0.032 | |
| lymphocyte proliferation | GO:0046651 | 70 | 0.032 | |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 51 | 0.031 | |
| glycoprotein biosynthetic process | GO:0009101 | 91 | 0.031 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.031 | |
| protein k48 linked ubiquitination | GO:0070936 | 38 | 0.030 | |
| sensory organ morphogenesis | GO:0090596 | 21 | 0.030 | |
| developmental maturation | GO:0021700 | 28 | 0.030 | |
| interspecies interaction between organisms | GO:0044419 | 156 | 0.030 | |
| camera type eye development | GO:0043010 | 25 | 0.029 | |
| er nucleus signaling pathway | GO:0006984 | 23 | 0.029 | |
| signal transduction involved in mitotic dna integrity checkpoint | GO:1902403 | 13 | 0.028 | |
| cell cycle arrest | GO:0007050 | 71 | 0.028 | |
| negative regulation of viral release from host cell | GO:1902187 | 12 | 0.028 | |
| regulation of rna splicing | GO:0043484 | 62 | 0.028 | |
| meiotic nuclear division | GO:0007126 | 10 | 0.027 | |
| mrna stabilization | GO:0048255 | 18 | 0.027 | |
| central nervous system development | GO:0007417 | 123 | 0.027 | |
| regulation of rna stability | GO:0043487 | 23 | 0.026 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.026 | |
| regulation of double strand break repair | GO:2000779 | 22 | 0.026 | |
| embryonic eye morphogenesis | GO:0048048 | 2 | 0.026 | |
| establishment or maintenance of bipolar cell polarity | GO:0061245 | 2 | 0.026 | |
| chondrocyte differentiation | GO:0002062 | 17 | 0.026 | |
| embryonic camera type eye morphogenesis | GO:0048596 | 2 | 0.026 | |
| cellular modified amino acid metabolic process | GO:0006575 | 64 | 0.026 | |
| proteasomal ubiquitin independent protein catabolic process | GO:0010499 | 3 | 0.026 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 156 | 0.026 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.025 | |
| protein glycosylation | GO:0006486 | 62 | 0.025 | |
| notch signaling pathway | GO:0007219 | 31 | 0.025 | |
| wound healing | GO:0042060 | 115 | 0.025 | |
| regulation of lymphocyte proliferation | GO:0050670 | 64 | 0.025 | |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.024 | |
| glycoprotein metabolic process | GO:0009100 | 110 | 0.024 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.024 | |
| regulation of system process | GO:0044057 | 101 | 0.024 | |
| regulation of protein transport | GO:0051223 | 213 | 0.024 | |
| b cell proliferation | GO:0042100 | 22 | 0.024 | |
| embryonic organ development | GO:0048568 | 36 | 0.024 | |
| cell death in response to oxidative stress | GO:0036473 | 29 | 0.024 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 44 | 0.024 | |
| er to golgi vesicle mediated transport | GO:0006888 | 19 | 0.023 | |
| protein acetylation | GO:0006473 | 116 | 0.023 | |
| cellular response to organic cyclic compound | GO:0071407 | 127 | 0.023 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.023 | |
| male meiosis | GO:0007140 | 1 | 0.023 | |
| regulation of intracellular steroid hormone receptor signaling pathway | GO:0033143 | 32 | 0.023 | |
| regulation of cell growth | GO:0001558 | 135 | 0.023 | |
| regulation of notch signaling pathway | GO:0008593 | 18 | 0.022 | |
| vesicle targeting rough er to cis golgi | GO:0048207 | 2 | 0.022 | |
| viral life cycle | GO:0019058 | 132 | 0.022 | |
| epidermis development | GO:0008544 | 59 | 0.022 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 35 | 0.022 | |
| pathway restricted smad protein phosphorylation | GO:0060389 | 38 | 0.022 | |
| developmental growth | GO:0048589 | 48 | 0.022 | Worm |
| citrate metabolic process | GO:0006101 | 2 | 0.022 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.022 | |
| copii vesicle coating | GO:0048208 | 2 | 0.021 | |
| amine metabolic process | GO:0009308 | 44 | 0.021 | |
| camera type eye morphogenesis | GO:0048593 | 12 | 0.021 | |
| positive regulation of transcription initiation from rna polymerase ii promoter | GO:0060261 | 4 | 0.021 | |
| regulation of cell activation | GO:0050865 | 125 | 0.021 | |
| response to other organism | GO:0051707 | 261 | 0.021 | |
| embryonic skeletal system morphogenesis | GO:0048704 | 9 | 0.021 | |
| system process | GO:0003008 | 349 | 0.021 | |
| cell cycle g1 s phase transition | GO:0044843 | 80 | 0.021 | |
| positive regulation of cell cycle process | GO:0090068 | 106 | 0.021 | |
| genetic imprinting | GO:0071514 | 1 | 0.021 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.021 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.020 | |
| regulation of metal ion transport | GO:0010959 | 120 | 0.020 | |
| negative regulation of dna replication | GO:0008156 | 29 | 0.020 | |
| establishment of apical basal cell polarity | GO:0035089 | 1 | 0.020 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 38 | 0.020 | |
| glycosylation | GO:0070085 | 71 | 0.020 | |
| multicellular organism reproduction | GO:0032504 | 42 | 0.020 | |
| embryonic skeletal system development | GO:0048706 | 13 | 0.020 | |
| regulation of potassium ion transmembrane transporter activity | GO:1901016 | 16 | 0.020 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.019 | |
| regulation of viral transcription | GO:0046782 | 34 | 0.019 | |
| negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:2000059 | 3 | 0.019 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 82 | 0.019 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.019 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.019 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 34 | 0.019 | Worm |
| neuron projection guidance | GO:0097485 | 12 | 0.019 | |
| methylation dependent chromatin silencing | GO:0006346 | 3 | 0.019 | |
| regulation of ion transport | GO:0043269 | 189 | 0.019 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.018 | |
| positive regulation of wnt signaling pathway | GO:0030177 | 54 | 0.018 | |
| cell projection organization | GO:0030030 | 252 | 0.018 | |
| regulation of actin filament based process | GO:0032970 | 141 | 0.018 | |
| negative regulation of multi organism process | GO:0043901 | 92 | 0.018 | |
| monoubiquitinated protein deubiquitination | GO:0035520 | 6 | 0.018 | |
| stem cell division | GO:0017145 | 2 | 0.018 | |
| appendage development | GO:0048736 | 23 | 0.018 | |
| negative regulation of intracellular transport | GO:0032387 | 60 | 0.018 | |
| histone lysine methylation | GO:0034968 | 50 | 0.018 | |
| regulation of transcription involved in g1 s transition of mitotic cell cycle | GO:0000083 | 8 | 0.018 | |
| regulation of gene expression epigenetic | GO:0040029 | 73 | 0.018 | Fly |
| rhythmic process | GO:0048511 | 31 | 0.018 | |
| b cell activation | GO:0042113 | 33 | 0.017 | |
| rna interference | GO:0016246 | 4 | 0.017 | |
| positive regulation of intracellular transport | GO:0032388 | 104 | 0.017 | |
| viral transcription | GO:0019083 | 35 | 0.017 | |
| regulation of cytokine mediated signaling pathway | GO:0001959 | 41 | 0.017 | |
| regulation of mrna export from nucleus | GO:0010793 | 3 | 0.017 | |
| regulation of mrna metabolic process | GO:1903311 | 53 | 0.017 | |
| response to heat | GO:0009408 | 21 | 0.017 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.017 | Rat |
| protein maturation | GO:0051604 | 233 | 0.017 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.017 | |
| regulation of neurogenesis | GO:0050767 | 82 | 0.017 | |
| sexual reproduction | GO:0019953 | 37 | 0.017 | |
| vesicle organization | GO:0016050 | 62 | 0.017 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.017 | |
| retina development in camera type eye | GO:0060041 | 15 | 0.017 | |
| regulation of protein import into nucleus | GO:0042306 | 78 | 0.016 | |
| regulation of cell projection organization | GO:0031344 | 107 | 0.016 | |
| ncrna processing | GO:0034470 | 83 | 0.016 | |
| prostate gland development | GO:0030850 | 3 | 0.016 | |
| response to antibiotic | GO:0046677 | 15 | 0.016 | |