| positive regulation of phosphorylation | GO:0042327 | 394 | 0.995 | Fly |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.989 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.982 | |
| membrane depolarization during action potential | GO:0086010 | 10 | 0.976 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.973 | |
| asymmetric neuroblast division | GO:0055059 | 1 | 0.966 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.962 | Human |
| cell development | GO:0048468 | 328 | 0.956 | Human Fly |
| growth | GO:0040007 | 202 | 0.952 | |
| establishment or maintenance of microtubule cytoskeleton polarity | GO:0030951 | 2 | 0.944 | Fly |
| oogenesis | GO:0048477 | 2 | 0.943 | Fly |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.939 | Fly |
| regulation of neuron differentiation | GO:0045664 | 70 | 0.929 | Human |
| dna replication | GO:0006260 | 116 | 0.918 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.915 | |
| sodium ion transmembrane transport | GO:0035725 | 59 | 0.908 | |
| cell fate determination | GO:0001709 | 3 | 0.904 | Worm Fly |
| ras protein signal transduction | GO:0007265 | 73 | 0.893 | Fly |
| oocyte differentiation | GO:0009994 | 2 | 0.876 | Fly |
| single organism cellular localization | GO:1902580 | 332 | 0.864 | Worm |
| activation of protein kinase activity | GO:0032147 | 90 | 0.851 | |
| mitochondrion organization | GO:0007005 | 156 | 0.846 | Human |
| dna dependent dna replication | GO:0006261 | 44 | 0.841 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.822 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.814 | |
| sodium ion transport | GO:0006814 | 61 | 0.791 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 75 | 0.791 | Fly |
| female gamete generation | GO:0007292 | 2 | 0.788 | Fly |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.773 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.765 | |
| cellular potassium ion transport | GO:0071804 | 60 | 0.760 | Human |
| positive regulation of developmental process | GO:0051094 | 314 | 0.753 | |
| oocyte development | GO:0048599 | 1 | 0.751 | Fly |
| neuroblast division | GO:0055057 | 1 | 0.745 | |
| neuronal stem cell division | GO:0036445 | 1 | 0.745 | |
| establishment or maintenance of cytoskeleton polarity | GO:0030952 | 3 | 0.744 | Fly |
| neuroblast proliferation | GO:0007405 | 4 | 0.741 | |
| regulation of sodium ion transmembrane transporter activity | GO:2000649 | 17 | 0.725 | |
| protein targeting to nucleus | GO:0044744 | 104 | 0.720 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.717 | |
| potassium ion transmembrane transport | GO:0071805 | 60 | 0.713 | Human |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 83 | 0.712 | |
| cation transport | GO:0006812 | 331 | 0.703 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.698 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.686 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.685 | |
| neuron differentiation | GO:0030182 | 138 | 0.678 | Human |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.671 | |
| regulation of cell diameter | GO:0060305 | 1 | 0.663 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.662 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.662 | |
| response to growth factor | GO:0070848 | 205 | 0.653 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.648 | |
| stem cell division | GO:0017145 | 2 | 0.644 | |
| protein dephosphorylation | GO:0006470 | 81 | 0.641 | Human |
| response to abiotic stimulus | GO:0009628 | 336 | 0.636 | Fly |
| potassium ion transport | GO:0006813 | 62 | 0.631 | Human |
| regulation of mapk cascade | GO:0043408 | 262 | 0.630 | Fly |
| glucocorticoid catabolic process | GO:0006713 | 1 | 0.627 | |
| regulation of peptidyl serine dephosphorylation | GO:1902308 | 2 | 0.612 | Human |
| regulation of membrane repolarization | GO:0060306 | 16 | 0.612 | Human |
| nuclear transport | GO:0051169 | 179 | 0.603 | |
| apoptotic mitochondrial changes | GO:0008637 | 57 | 0.597 | Human |
| establishment or maintenance of cell polarity | GO:0007163 | 31 | 0.595 | Worm Fly |
| membrane repolarization | GO:0086009 | 23 | 0.588 | Human |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.574 | Human |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.568 | Fly |
| cell projection organization | GO:0030030 | 252 | 0.560 | |
| steroid catabolic process | GO:0006706 | 10 | 0.557 | |
| neurogenesis | GO:0022008 | 169 | 0.548 | Human |
| establishment or maintenance of apical basal cell polarity | GO:0035088 | 2 | 0.533 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.531 | |
| nuclear migration | GO:0007097 | 1 | 0.522 | Worm |
| regulation of neuron projection development | GO:0010975 | 57 | 0.513 | |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.512 | |
| asymmetric stem cell division | GO:0098722 | 1 | 0.505 | |
| inorganic cation transmembrane transport | GO:0098662 | 194 | 0.505 | |
| metal ion transport | GO:0030001 | 272 | 0.493 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.492 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.490 | Worm |
| lipid catabolic process | GO:0016042 | 84 | 0.489 | |
| regulation of transporter activity | GO:0032409 | 82 | 0.478 | |
| regulation of transmembrane transporter activity | GO:0022898 | 74 | 0.465 | |
| regulation of cell development | GO:0060284 | 161 | 0.462 | Human |
| monovalent inorganic cation transport | GO:0015672 | 128 | 0.461 | |
| regulation of cellular component size | GO:0032535 | 82 | 0.461 | |
| regulation of nervous system development | GO:0051960 | 88 | 0.460 | Human |
| regulation of membrane potential | GO:0042391 | 95 | 0.458 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.458 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.457 | |
| positive regulation of dna templated transcription elongation | GO:0032786 | 18 | 0.455 | |
| response to radiation | GO:0009314 | 151 | 0.447 | |
| cell cell signaling | GO:0007267 | 155 | 0.446 | Human |
| negative regulation of myotube differentiation | GO:0010832 | 4 | 0.443 | |
| cell division | GO:0051301 | 168 | 0.439 | Worm |
| positive regulation of ras gtpase activity | GO:0032320 | 117 | 0.439 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.436 | |
| negative regulation of cell size | GO:0045792 | 3 | 0.435 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.424 | Fly |
| embryonic morphogenesis | GO:0048598 | 85 | 0.419 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.415 | Human |
| regulation of sodium ion transport | GO:0002028 | 24 | 0.410 | |
| peptidyl serine dephosphorylation | GO:0070262 | 2 | 0.403 | Human |
| amine metabolic process | GO:0009308 | 44 | 0.401 | |
| lipid metabolic process | GO:0006629 | 381 | 0.397 | |
| mapk cascade | GO:0000165 | 288 | 0.395 | Fly |
| regulation of cell projection organization | GO:0031344 | 107 | 0.380 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 90 | 0.364 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.360 | |
| oocyte maturation | GO:0001556 | 1 | 0.350 | |
| protein targeting | GO:0006605 | 187 | 0.347 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.346 | |
| rho protein signal transduction | GO:0007266 | 26 | 0.332 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.328 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 4 | 0.328 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.320 | |
| stem cell development | GO:0048864 | 69 | 0.318 | |
| regulation of neurogenesis | GO:0050767 | 82 | 0.313 | Human |
| regulation of erk1 and erk2 cascade | GO:0070372 | 99 | 0.309 | Fly |
| regulation of ion transport | GO:0043269 | 189 | 0.306 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.305 | |
| regulation of sodium ion transmembrane transport | GO:1902305 | 23 | 0.305 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.305 | |
| response to light stimulus | GO:0009416 | 87 | 0.303 | |
| regulation of potassium ion transmembrane transport | GO:1901379 | 20 | 0.303 | Human |
| regulation of potassium ion transport | GO:0043266 | 24 | 0.298 | Human |
| generation of neurons | GO:0048699 | 152 | 0.297 | Human |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.296 | |
| microtubule based process | GO:0007017 | 210 | 0.294 | Worm Fly |
| cell junction organization | GO:0034330 | 79 | 0.294 | |
| cell growth | GO:0016049 | 160 | 0.289 | |
| glucocorticoid metabolic process | GO:0008211 | 10 | 0.282 | |
| positive regulation of meiotic cell cycle | GO:0051446 | 2 | 0.279 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.277 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.277 | Worm |
| single organism membrane organization | GO:0044802 | 268 | 0.276 | |
| somatic stem cell division | GO:0048103 | 1 | 0.276 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.258 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.257 | Human |
| release of cytochrome c from mitochondria | GO:0001836 | 35 | 0.255 | Human |
| maintenance of protein location | GO:0045185 | 57 | 0.254 | Human |
| epithelial cell proliferation | GO:0050673 | 128 | 0.247 | |
| tube morphogenesis | GO:0035239 | 95 | 0.247 | |
| regulation of vesicle mediated transport | GO:0060627 | 130 | 0.246 | |
| cation transmembrane transport | GO:0098655 | 238 | 0.245 | |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.245 | Fly |
| cytoplasmic sequestering of protein | GO:0051220 | 12 | 0.244 | Human |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.243 | |
| oxidation reduction process | GO:0055114 | 396 | 0.241 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.236 | Worm Fly |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.236 | |
| embryonic epithelial tube formation | GO:0001838 | 4 | 0.233 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.233 | |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.231 | |
| dna replication initiation | GO:0006270 | 6 | 0.229 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.226 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 72 | 0.225 | |
| monosaccharide metabolic process | GO:0005996 | 74 | 0.225 | |
| membrane organization | GO:0061024 | 292 | 0.224 | |
| male meiosis | GO:0007140 | 1 | 0.223 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.221 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.219 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.218 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.218 | |
| cytokinesis | GO:0000910 | 96 | 0.217 | |
| photoreceptor cell differentiation | GO:0046530 | 2 | 0.216 | |
| protein localization to organelle | GO:0033365 | 280 | 0.214 | |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.213 | Fly |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.210 | Human |
| plasma membrane organization | GO:0007009 | 115 | 0.208 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.203 | Human |
| regulation of transcription factor import into nucleus | GO:0042990 | 39 | 0.202 | |
| intracellular receptor signaling pathway | GO:0030522 | 104 | 0.202 | |
| intracellular protein transport | GO:0006886 | 270 | 0.200 | |
| regulation of potassium ion transmembrane transporter activity | GO:1901016 | 16 | 0.198 | Human |
| regulation of metal ion transport | GO:0010959 | 120 | 0.198 | |
| embryo development | GO:0009790 | 123 | 0.198 | Worm Fly |
| inorganic ion transmembrane transport | GO:0098660 | 231 | 0.197 | |
| positive regulation of neuron differentiation | GO:0045666 | 40 | 0.193 | |
| anterior posterior axis specification | GO:0009948 | 2 | 0.189 | Worm |
| anterior posterior axis specification embryo | GO:0008595 | 2 | 0.188 | |
| establishment of cell polarity | GO:0030010 | 22 | 0.187 | Worm |
| regulation of anatomical structure size | GO:0090066 | 101 | 0.186 | |
| regulation of growth | GO:0040008 | 165 | 0.184 | |
| wnt signaling pathway | GO:0016055 | 156 | 0.184 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.184 | Human |
| peptidyl serine modification | GO:0018209 | 106 | 0.181 | |
| cellular response to uv | GO:0034644 | 32 | 0.178 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.177 | |
| regulation of ion transmembrane transport | GO:0034765 | 132 | 0.176 | |
| tor signaling | GO:0031929 | 39 | 0.176 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.176 | Worm Fly |
| multicellular organismal aging | GO:0010259 | 3 | 0.175 | Worm |
| negative regulation of cell death | GO:0060548 | 345 | 0.175 | Human |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.175 | |
| cell morphogenesis | GO:0000902 | 296 | 0.172 | |
| somatic muscle development | GO:0007525 | 1 | 0.171 | |
| positive regulation of small gtpase mediated signal transduction | GO:0051057 | 12 | 0.166 | Fly |
| establishment of nucleus localization | GO:0040023 | 1 | 0.163 | Worm |
| neural tube formation | GO:0001841 | 3 | 0.163 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.162 | |
| transcription factor import into nucleus | GO:0042991 | 40 | 0.161 | |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.159 | |
| positive regulation of anoikis | GO:2000210 | 4 | 0.157 | |
| cellular component disassembly | GO:0022411 | 92 | 0.154 | |
| limbic system development | GO:0021761 | 3 | 0.153 | |
| regulation of epithelial to mesenchymal transition | GO:0010717 | 37 | 0.153 | |
| endomembrane system organization | GO:0010256 | 196 | 0.152 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.151 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.151 | Worm |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.150 | Human |
| response to uv | GO:0009411 | 73 | 0.149 | |
| cell fate commitment | GO:0045165 | 27 | 0.148 | Worm Fly |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.146 | Human |
| glycogen metabolic process | GO:0005977 | 22 | 0.146 | |
| positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation | GO:0003257 | 3 | 0.144 | |
| cell migration involved in sprouting angiogenesis | GO:0002042 | 19 | 0.144 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.142 | Worm |
| peptidyl lysine modification | GO:0018205 | 144 | 0.142 | |
| epithelial cell migration | GO:0010631 | 119 | 0.140 | |
| behavior | GO:0007610 | 112 | 0.140 | Worm Fly |
| endocytosis | GO:0006897 | 159 | 0.139 | Worm |
| muscle structure development | GO:0061061 | 98 | 0.139 | |
| cell projection assembly | GO:0030031 | 126 | 0.138 | |
| neuron projection development | GO:0031175 | 106 | 0.137 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.136 | |
| negative regulation of transport | GO:0051051 | 176 | 0.136 | Human |
| response to nitrogen compound | GO:1901698 | 184 | 0.136 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.134 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.134 | |
| vasculature development | GO:0001944 | 181 | 0.131 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.131 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.130 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.128 | |
| mesenchymal cell development | GO:0014031 | 50 | 0.128 | |
| negative regulation of peptidyl serine dephosphorylation | GO:1902309 | 1 | 0.128 | Human |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 156 | 0.127 | Fly |
| positive regulation of cell projection organization | GO:0031346 | 64 | 0.127 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.126 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.126 | |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.125 | Human |
| positive regulation of protein import into nucleus | GO:0042307 | 46 | 0.124 | |
| regulation of cell migration | GO:0030334 | 289 | 0.123 | |
| positive regulation of neuron projection development | GO:0010976 | 34 | 0.123 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.122 | |
| gastrulation | GO:0007369 | 51 | 0.122 | |
| organ morphogenesis | GO:0009887 | 147 | 0.120 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.119 | Human |
| digestive tract development | GO:0048565 | 75 | 0.119 | |
| regulation of neurotransmitter secretion | GO:0046928 | 3 | 0.119 | |
| maintenance of location in cell | GO:0051651 | 62 | 0.119 | Human |
| digestive system development | GO:0055123 | 75 | 0.118 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.117 | |
| single organism nuclear import | GO:1902593 | 104 | 0.117 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.116 | |
| regulation of actin filament based process | GO:0032970 | 141 | 0.115 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.115 | Human |
| positive regulation of map kinase activity | GO:0043406 | 80 | 0.114 | |
| protein localization to plasma membrane | GO:0072659 | 93 | 0.113 | |
| cell cycle arrest | GO:0007050 | 71 | 0.113 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.113 | |
| tripartite regional subdivision | GO:0007351 | 2 | 0.113 | |
| tissue migration | GO:0090130 | 119 | 0.112 | |
| meiosis i | GO:0007127 | 4 | 0.112 | |
| corticosteroid receptor signaling pathway | GO:0031958 | 5 | 0.111 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.111 | Human |
| cellular carbohydrate metabolic process | GO:0044262 | 84 | 0.109 | |
| regulation of synaptic plasticity | GO:0048167 | 3 | 0.108 | Human |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.108 | |
| synaptic transmission | GO:0007268 | 61 | 0.106 | Human |
| generation of precursor metabolites and energy | GO:0006091 | 68 | 0.106 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.106 | |
| negative regulation of exit from mitosis | GO:0001100 | 1 | 0.106 | |
| meiotic chromosome segregation | GO:0045132 | 4 | 0.106 | |
| chemical homeostasis | GO:0048878 | 306 | 0.105 | |
| regulation of epithelial cell migration | GO:0010632 | 93 | 0.104 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.103 | Human |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.102 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.102 | Fly |
| dephosphorylation | GO:0016311 | 209 | 0.100 | Human |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.100 | |
| transmembrane transport | GO:0055085 | 399 | 0.099 | |
| gtp metabolic process | GO:0046039 | 239 | 0.099 | |
| chromatin organization | GO:0006325 | 351 | 0.098 | |
| mitotic nuclear division | GO:0007067 | 119 | 0.096 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 10 | 0.095 | |
| cardiovascular system development | GO:0072358 | 262 | 0.095 | |
| nuclear division | GO:0000280 | 128 | 0.095 | Worm |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.095 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.095 | |
| organelle assembly | GO:0070925 | 176 | 0.095 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.095 | |
| regulation of transmembrane transport | GO:0034762 | 139 | 0.094 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.094 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.093 | |
| negative regulation of protein transport | GO:0051224 | 75 | 0.093 | Human |
| negative regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043154 | 46 | 0.092 | Human |
| regulation of protein localization | GO:0032880 | 296 | 0.092 | Human |
| protein import into nucleus | GO:0006606 | 104 | 0.090 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.090 | |
| digestive tract morphogenesis | GO:0048546 | 56 | 0.089 | |
| gtp catabolic process | GO:0006184 | 237 | 0.089 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.088 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.086 | |
| nervous system development | GO:0007399 | 293 | 0.086 | |
| regulation of ras gtpase activity | GO:0032318 | 128 | 0.086 | |
| regulation of protein processing | GO:0070613 | 150 | 0.085 | Human |
| endothelial cell migration | GO:0043542 | 86 | 0.085 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 119 | 0.085 | |
| microtubule organizing center organization | GO:0031023 | 62 | 0.085 | |
| positive regulation of endothelial cell migration | GO:0010595 | 39 | 0.084 | |
| regulation of rho gtpase activity | GO:0032319 | 66 | 0.084 | |
| regulation of map kinase activity | GO:0043405 | 108 | 0.083 | |
| maintenance of location | GO:0051235 | 112 | 0.083 | Human |
| positive regulation of peptidyl serine phosphorylation | GO:0033138 | 42 | 0.083 | |
| regulation of cell motility | GO:2000145 | 299 | 0.083 | |
| regulation of rho protein signal transduction | GO:0035023 | 79 | 0.082 | |
| neurological system process | GO:0050877 | 163 | 0.082 | Fly |
| defense response | GO:0006952 | 315 | 0.082 | |
| actin filament based process | GO:0030029 | 224 | 0.081 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.080 | |
| positive regulation of cell development | GO:0010720 | 92 | 0.079 | |
| mesenchymal to epithelial transition involved in metanephros morphogenesis | GO:0003337 | 4 | 0.078 | |
| positive regulation of transport | GO:0051050 | 336 | 0.078 | |
| cell junction assembly | GO:0034329 | 67 | 0.078 | |
| negative regulation of dephosphorylation | GO:0035305 | 63 | 0.077 | Human |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.077 | |
| negative regulation of chromatin silencing | GO:0031936 | 4 | 0.077 | |
| regulation of epithelial cell proliferation | GO:0050678 | 113 | 0.077 | |
| peptidyl tyrosine dephosphorylation | GO:0035335 | 36 | 0.075 | |
| renal system development | GO:0072001 | 63 | 0.073 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 4 | 0.073 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.073 | |
| single fertilization | GO:0007338 | 11 | 0.073 | Worm |
| blastoderm segmentation | GO:0007350 | 2 | 0.072 | |
| negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle | GO:0051436 | 4 | 0.072 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.072 | |
| positive regulation of cell division | GO:0051781 | 59 | 0.072 | |
| protein ubiquitination | GO:0016567 | 314 | 0.070 | |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 61 | 0.070 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.069 | |
| regulation of endocytosis | GO:0030100 | 72 | 0.069 | |
| centrosome organization | GO:0051297 | 58 | 0.069 | |
| axon cargo transport | GO:0008088 | 2 | 0.069 | |
| protein dna complex subunit organization | GO:0071824 | 80 | 0.068 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.068 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.068 | |
| regulation of synaptic transmission | GO:0050804 | 11 | 0.068 | Human |
| cell cell junction organization | GO:0045216 | 69 | 0.068 | |
| negative regulation of map kinase activity | GO:0043407 | 27 | 0.067 | |
| brain development | GO:0007420 | 97 | 0.067 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.067 | |
| receptor mediated endocytosis | GO:0006898 | 84 | 0.067 | Worm |
| establishment or maintenance of bipolar cell polarity | GO:0061245 | 2 | 0.067 | |
| visual learning | GO:0008542 | 1 | 0.067 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.067 | |
| regulation of protein localization to plasma membrane | GO:1903076 | 40 | 0.066 | |
| midbrain development | GO:0030901 | 45 | 0.066 | |
| regulation of protein dephosphorylation | GO:0035304 | 18 | 0.066 | Human |
| regulation of exocytosis | GO:0017157 | 46 | 0.066 | |
| organelle fission | GO:0048285 | 149 | 0.066 | Worm |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.066 | |
| regulation of cellular response to growth factor stimulus | GO:0090287 | 76 | 0.064 | |
| regulation of homeostatic process | GO:0032844 | 121 | 0.064 | |
| cellular response to mechanical stimulus | GO:0071260 | 39 | 0.063 | |
| positive regulation of cytokinesis | GO:0032467 | 29 | 0.063 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 76 | 0.063 | |
| protein acylation | GO:0043543 | 138 | 0.063 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.062 | Human |
| positive regulation of blood vessel endothelial cell migration | GO:0043536 | 16 | 0.061 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.060 | |
| blood vessel endothelial cell migration | GO:0043534 | 42 | 0.060 | |
| single organism reproductive process | GO:0044702 | 98 | 0.059 | Worm Fly |
| head development | GO:0060322 | 108 | 0.058 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.058 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.057 | |
| positive regulation of neurogenesis | GO:0050769 | 49 | 0.057 | |
| pattern specification process | GO:0007389 | 43 | 0.057 | Worm Fly |
| anoikis | GO:0043276 | 22 | 0.057 | |
| eye photoreceptor cell differentiation | GO:0001754 | 2 | 0.057 | |
| regulation of dendrite development | GO:0050773 | 18 | 0.056 | |
| chromosome segregation | GO:0007059 | 114 | 0.056 | Fly |
| cell maturation | GO:0048469 | 11 | 0.056 | Fly |
| regulation of cytokinesis | GO:0032465 | 45 | 0.056 | |
| protein kinase b signaling | GO:0043491 | 69 | 0.056 | |
| regulation of protein kinase b signaling | GO:0051896 | 61 | 0.056 | |
| maintenance of protein location in cell | GO:0032507 | 56 | 0.055 | Human |
| rna processing | GO:0006396 | 255 | 0.055 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.055 | Human |
| polysaccharide metabolic process | GO:0005976 | 33 | 0.055 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.054 | Fly |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.054 | |
| specification of axis polarity | GO:0065001 | 1 | 0.054 | Worm |
| regulation of cellular component movement | GO:0051270 | 334 | 0.054 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.053 | |
| peptidyl threonine phosphorylation | GO:0018107 | 41 | 0.053 | |
| epithelial cell differentiation | GO:0030855 | 141 | 0.053 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.053 | |
| termination of signal transduction | GO:0023021 | 3 | 0.052 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 108 | 0.052 | |
| muscle organ development | GO:0007517 | 56 | 0.052 | |
| rac protein signal transduction | GO:0016601 | 12 | 0.051 | |
| protein maturation | GO:0051604 | 233 | 0.051 | Human |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.051 | |
| stem cell differentiation | GO:0048863 | 93 | 0.051 | |
| vesicle transport along microtubule | GO:0047496 | 4 | 0.051 | |
| regulation of protein targeting | GO:1903533 | 91 | 0.051 | |
| positive regulation of calcium ion transport | GO:0051928 | 51 | 0.050 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 50 | 0.050 | Human |
| glucocorticoid receptor signaling pathway | GO:0042921 | 5 | 0.049 | |
| protein processing | GO:0016485 | 226 | 0.049 | Human |
| epithelial tube morphogenesis | GO:0060562 | 38 | 0.049 | |
| divalent inorganic cation transport | GO:0072511 | 158 | 0.049 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.049 | Human |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.049 | |
| nucleus localization | GO:0051647 | 1 | 0.049 | Worm |
| calcium ion transport | GO:0006816 | 147 | 0.048 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.048 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.048 | |
| regulation of axonogenesis | GO:0050770 | 16 | 0.048 | |
| epithelium development | GO:0060429 | 227 | 0.048 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.048 | |
| regulation of protein transport | GO:0051223 | 213 | 0.048 | Human |
| positive regulation of synaptic transmission | GO:0050806 | 4 | 0.047 | |
| regulation of cardiac muscle contraction by calcium ion signaling | GO:0010882 | 3 | 0.047 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.047 | |
| response to transforming growth factor beta | GO:0071559 | 94 | 0.047 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 94 | 0.047 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.047 | |
| positive regulation of superoxide anion generation | GO:0032930 | 4 | 0.046 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.046 | Human |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 125 | 0.045 | |
| striated muscle cell differentiation | GO:0051146 | 43 | 0.045 | |
| regulation of stem cell differentiation | GO:2000736 | 56 | 0.045 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.045 | |
| regulation of synaptic vesicle transport | GO:1902803 | 3 | 0.045 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.045 | |
| muscle contraction | GO:0006936 | 73 | 0.045 | |
| regulation of locomotion | GO:0040012 | 329 | 0.045 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.044 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.044 | Human |
| negative regulation of locomotion | GO:0040013 | 118 | 0.043 | |
| centriole assembly | GO:0098534 | 14 | 0.043 | |
| system process | GO:0003008 | 349 | 0.043 | Fly |
| positive regulation of angiogenesis | GO:0045766 | 51 | 0.043 | |
| regulation of neural precursor cell proliferation | GO:2000177 | 4 | 0.043 | |
| regulation of mitosis | GO:0007088 | 63 | 0.043 | |
| negative regulation of microtubule polymerization or depolymerization | GO:0031111 | 17 | 0.042 | |
| peroxisome organization | GO:0007031 | 28 | 0.042 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.042 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.042 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.042 | Human |
| positive regulation of locomotion | GO:0040017 | 186 | 0.042 | |
| ion homeostasis | GO:0050801 | 230 | 0.042 | |
| regulation of branching involved in ureteric bud morphogenesis | GO:0090189 | 3 | 0.041 | |
| positive regulation of lipid biosynthetic process | GO:0046889 | 22 | 0.041 | |
| regulation of behavior | GO:0050795 | 82 | 0.041 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.041 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.041 | |
| mitochondrion distribution | GO:0048311 | 3 | 0.041 | |
| tube development | GO:0035295 | 125 | 0.041 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.041 | |
| neuron projection morphogenesis | GO:0048812 | 50 | 0.041 | |
| angiogenesis | GO:0001525 | 147 | 0.040 | |
| positive regulation of embryonic development | GO:0040019 | 6 | 0.040 | |
| response to hormone | GO:0009725 | 175 | 0.040 | |
| positive regulation of intracellular transport | GO:0032388 | 104 | 0.040 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.040 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.040 | |
| nuclear import | GO:0051170 | 106 | 0.040 | |
| neuron development | GO:0048666 | 113 | 0.040 | |
| epithelium migration | GO:0090132 | 119 | 0.040 | |
| stem cell proliferation | GO:0072089 | 25 | 0.040 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.039 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 81 | 0.039 | |
| epithelial to mesenchymal transition | GO:0001837 | 48 | 0.039 | |
| hindbrain development | GO:0030902 | 3 | 0.039 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.039 | |
| regulation of peptidyl serine phosphorylation | GO:0033135 | 50 | 0.038 | |
| regulation of blood circulation | GO:1903522 | 59 | 0.038 | |
| taxis | GO:0042330 | 157 | 0.038 | |
| negative regulation of cardiac muscle cell apoptotic process | GO:0010667 | 2 | 0.038 | |
| keratinization | GO:0031424 | 2 | 0.038 | |
| multicellular organismal response to stress | GO:0033555 | 1 | 0.038 | |
| regulation of protein import into nucleus | GO:0042306 | 78 | 0.038 | |
| regulation of embryonic development | GO:0045995 | 20 | 0.037 | |
| establishment of organelle localization | GO:0051656 | 59 | 0.037 | Worm |
| membrane depolarization | GO:0051899 | 26 | 0.037 | |
| regulation of lipid metabolic process | GO:0019216 | 96 | 0.037 | |
| regulation of jnk cascade | GO:0046328 | 73 | 0.037 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.037 | |
| negative regulation of protein ubiquitination | GO:0031397 | 35 | 0.037 | |
