Mus musculus

0 known processes

Plekhg4

pleckstrin homology domain containing, family G (with RhoGef domain) member 4

(Aliases: mFLJ00068,4931414L13Rik,AI448583)

Plekhg4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.111
regulation of cellular amino acid metabolic processGO:000652150.070
male gamete generationGO:00482322850.070
spermatogenesisGO:00072832840.059
amine metabolic processGO:0009308450.057
regionalizationGO:00030023370.054
cellular ketone metabolic processGO:0042180840.052
dna metabolic processGO:00062593030.050
nucleobase containing small molecule metabolic processGO:00550863520.049
regulation of cellular ketone metabolic processGO:0010565660.049
peptidyl amino acid modificationGO:00181933360.049
fertilizationGO:00095661270.048
proteolysis involved in cellular protein catabolic processGO:00516031470.046
macromolecule catabolic processGO:00090572810.045
cellular nitrogen compound catabolic processGO:00442702800.041
cellular macromolecule catabolic processGO:00442652060.041
regulation of transferase activityGO:00513382630.040
cell adhesionGO:00071553290.040
renal system developmentGO:00720012250.040
positive regulation of cell developmentGO:00107202370.040
regulation of cell adhesionGO:00301551540.040
regulation of cellular amine metabolic processGO:0033238200.039
negative regulation of molecular functionGO:00440922580.038
positive regulation of cellular amino acid metabolic processGO:004576430.036
cellular amine metabolic processGO:0044106440.036
regulation of protein kinase activityGO:00458592320.034
regulation of cellular catabolic processGO:00313292420.033
pole plasm assemblyGO:000731520.032
sensory organ morphogenesisGO:00905962420.031
aromatic compound catabolic processGO:00194392860.030
cellular protein catabolic processGO:00442571550.030
extracellular matrix organizationGO:00301981470.029
spermatid developmentGO:00072861080.029
negative regulation of protein metabolic processGO:00512482820.028
mitotic chromosome condensationGO:000707610.028
inorganic cation transmembrane transportGO:00986622070.028
protein maturationGO:00516041760.027
nucleotide metabolic processGO:00091173320.027
regulation of vesicle mediated transportGO:00606271390.027
protein catabolic processGO:00301632210.027
kidney developmentGO:00018222130.026
negative regulation of cellular protein metabolic processGO:00322692470.026
urogenital system developmentGO:00016552610.025
meiosis iGO:0007127600.025
positive regulation of transferase activityGO:00513471670.025
divalent metal ion transportGO:00708381720.025
protein processingGO:00164851630.024
purine nucleotide metabolic processGO:00061633020.024
glycosyl compound metabolic processGO:19016572460.024
purine ribonucleoside metabolic processGO:00461282410.024
cation transportGO:00068123990.023
positive regulation of cellular amine metabolic processGO:003324050.023
nucleoside phosphate metabolic processGO:00067533380.023
segmentationGO:0035282930.023
meiotic nuclear divisionGO:00071261150.023
meiotic cell cycleGO:00513211220.023
regulation of neuron differentiationGO:00456642810.023
carbohydrate metabolic processGO:00059752300.023
respiratory tube developmentGO:00303231670.023
oocyte axis specificationGO:000730920.023
cation transmembrane transportGO:00986552660.022
exocytosisGO:00068871210.022
respiratory system developmentGO:00605411900.022
purine nucleoside catabolic processGO:00061522050.022
nucleoside metabolic processGO:00091162460.022
germ cell developmentGO:00072811850.022
nuclear divisionGO:00002801580.022
chemotaxisGO:00069352470.022
ribose phosphate metabolic processGO:00196932910.022
intracellular protein transportGO:00068862040.022
male meiosisGO:0007140370.021
stem cell developmentGO:00488642190.021
protein localization to organelleGO:00333651850.021
organelle fissionGO:00482851700.021
heterocycle catabolic processGO:00467002800.021
organic cyclic compound catabolic processGO:19013612950.021
ribonucleotide catabolic processGO:00092612080.021
positive regulation of neuron differentiationGO:00456661410.021
adaptive immune responseGO:00022501550.021
extracellular structure organizationGO:00430621480.021
neuron deathGO:00709971540.021
oocyte constructionGO:000730820.021
negative regulation of protein modification processGO:00314001630.021
placenta developmentGO:00018901400.020
epithelial tube morphogenesisGO:00605623030.020
camera type eye developmentGO:00430102660.020
membrane organizationGO:00610242450.020
modification dependent macromolecule catabolic processGO:00436321330.020
lateral inhibitionGO:004633110.020
ribonucleoside metabolic processGO:00091192450.020
protein modification by small protein conjugationGO:00324461870.020
leukocyte differentiationGO:00025213420.020
ribonucleotide metabolic processGO:00092592910.019
blood circulationGO:00080151950.019
positive regulation of nervous system developmentGO:00519622210.019
synaptic transmissionGO:00072683290.019
positive regulation of protein modification processGO:00314012990.019
mrna metabolic processGO:0016071840.019
striated muscle tissue developmentGO:00147062930.019
lymphocyte differentiationGO:00300982420.019
microtubule based processGO:00070172360.019
oxidation reduction processGO:00551143420.019
cellular lipid metabolic processGO:00442553230.019
spermatid differentiationGO:00485151150.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
rna processingGO:00063961050.019
organonitrogen compound catabolic processGO:19015652640.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.018
dna methylation involved in gamete generationGO:0043046150.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.018
positive regulation of programmed cell deathGO:00430682180.018
positive regulation of kinase activityGO:00336741550.018
small gtpase mediated signal transductionGO:0007264970.018
stem cell differentiationGO:00488632680.018
gland developmentGO:00487323300.018
divalent inorganic cation transportGO:00725111780.018
protein targetingGO:00066051430.018
regulation of cell cycleGO:00517262810.018
retina development in camera type eyeGO:00600411190.018
peptidyl tyrosine phosphorylationGO:00181081430.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
regulation of response to woundingGO:19030341890.018
transmission of nerve impulseGO:0019226760.018
monocarboxylic acid metabolic processGO:00327871910.017
protein ubiquitinationGO:00165671710.017
neuron apoptotic processGO:00514021420.017
ribonucleoside catabolic processGO:00424542060.017
chromatin organizationGO:00063252060.017
mrna processingGO:0006397630.017
response to organonitrogen compoundGO:00102432460.017
leukocyte mediated immunityGO:00024431740.017
cellularizationGO:000734910.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
regulation of apoptotic signaling pathwayGO:20012331970.017
female gonad developmentGO:0008585710.017
nucleoside phosphate catabolic processGO:19012922220.017
nucleoside triphosphate metabolic processGO:00091412300.017
regulation of intracellular transportGO:00323861590.017
positive regulation of cellular catabolic processGO:00313311480.017
regulation of defense responseGO:00313472330.016
reactive oxygen species metabolic processGO:0072593840.016
response to organic cyclic compoundGO:00140701980.016
maternal determination of anterior posterior axis embryoGO:000835820.016
development of primary sexual characteristicsGO:00451371430.016
sensory perceptionGO:00076002450.016
methylationGO:00322591340.016
posttranscriptional regulation of gene expressionGO:00106081550.016
organophosphate catabolic processGO:00464342320.016
inorganic ion transmembrane transportGO:00986602340.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.016
embryonic epithelial tube formationGO:00018381300.016
cellular response to organonitrogen compoundGO:00714171450.016
heart morphogenesisGO:00030071780.016
g protein coupled receptor signaling pathwayGO:00071862430.016
positive regulation of growthGO:00459271040.016
negative regulation of protein phosphorylationGO:00019331260.016
purine nucleotide catabolic processGO:00061952110.016
cytokine productionGO:00018163190.016
skeletal system developmentGO:00015013560.016
embryonic organ morphogenesisGO:00485622760.016
modification dependent protein catabolic processGO:00199411330.015
cell cell recognitionGO:0009988440.015
apoptotic signaling pathwayGO:00971903060.015
b cell activationGO:00421131610.015
purine ribonucleotide metabolic processGO:00091502900.015
immune effector processGO:00022523210.015
connective tissue developmentGO:00614481790.015
ubiquitin dependent protein catabolic processGO:00065111290.015
digestive system developmentGO:00551232000.015
cellular ion homeostasisGO:00068731650.015
nephron developmentGO:00720061090.015
organonitrogen compound biosynthetic processGO:19015661920.015
muscle cell differentiationGO:00426922610.015
ribonucleoside triphosphate catabolic processGO:00092031990.015
positive regulation of cell deathGO:00109422240.015
single fertilizationGO:0007338820.015
rna interferenceGO:001624620.015
purine nucleoside metabolic processGO:00422782410.015
organic anion transportGO:00157111370.015
regulation of neuron deathGO:19012141340.015
regulation of protein processingGO:0070613960.015
regulation of mapk cascadeGO:00434082480.015
regulation of cellular protein catabolic processGO:1903362610.015
nucleotide catabolic processGO:00091662170.015
cytoplasmic transportGO:00164822340.014
skeletal system morphogenesisGO:00487052030.014
endocytosisGO:00068971680.014
regulation of protein catabolic processGO:00421761080.014
regulation of membrane potentialGO:00423911920.014
gonad developmentGO:00084061410.014
multicellular organism growthGO:00352641610.014
regulation of hormone levelsGO:00108172110.014
lung developmentGO:00303241640.014
lymphocyte mediated immunityGO:00024491390.014
regulation of cell activationGO:00508652890.014
purine ribonucleotide catabolic processGO:00091542080.014
cellular chemical homeostasisGO:00550822150.014
single organism cell adhesionGO:00986021560.014
dna recombinationGO:0006310920.014
circulatory system processGO:00030131970.014
protein modification by small protein conjugation or removalGO:00706472070.014
regulation of nucleotide metabolic processGO:00061401690.014
oocyte anterior posterior axis specificationGO:000731420.014
regulation of purine nucleotide metabolic processGO:19005421690.014
cellular carbohydrate metabolic processGO:00442621190.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
renal tubule developmentGO:0061326870.014
neural tube developmentGO:00219151600.014
purine containing compound metabolic processGO:00725213110.013
histone modificationGO:00165701590.013
sensory system developmentGO:004888030.013
establishment of protein localization to organelleGO:00725941180.013
nucleoside monophosphate metabolic processGO:0009123850.013
sperm egg recognitionGO:0035036370.013
neuronal action potentialGO:0019228540.013
negative regulation of cellular amine metabolic processGO:003323910.013
regulation of protein localizationGO:00328802310.013
developmental growth involved in morphogenesisGO:00605601380.013
regulation of sequence specific dna binding transcription factor activityGO:00510901060.013
regulation of neuron projection developmentGO:00109751690.013
alcohol metabolic processGO:00060661160.013
regulation of kinase activityGO:00435492490.013
regulation of protein serine threonine kinase activityGO:00719001570.013
negative regulation of neuron apoptotic processGO:0043524920.013
nucleoside catabolic processGO:00091642060.013
regulation of exocytosisGO:0017157610.013
alpha amino acid metabolic processGO:1901605590.013
negative regulation of phosphorylationGO:00423261660.013
nucleoside triphosphate catabolic processGO:00091432050.013
anion transportGO:00068201770.013
skin developmentGO:00435882200.013
anatomical structure homeostasisGO:00602491450.013
regulation of proteolysisGO:00301621640.013
male meiosis iGO:0007141160.013
embryonic placenta developmentGO:0001892980.013
mesodermal cell migrationGO:000807840.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
organelle localizationGO:00516401790.013
regulation of organelle organizationGO:00330432890.013
ras protein signal transductionGO:0007265770.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
positive regulation of cell adhesionGO:0045785800.013
positive regulation of protein kinase activityGO:00458601440.013
peptidyl serine modificationGO:0018209830.013
negative regulation of cell proliferationGO:00082852960.013
mitotic cell cycle processGO:19030471590.012
ameboidal type cell migrationGO:00016671280.012
hematopoietic progenitor cell differentiationGO:00022441430.012
cardiac ventricle developmentGO:0003231830.012
response to growth factorGO:00708481980.012
proteasomal protein catabolic processGO:0010498980.012
mitotic cell cycleGO:00002781950.012
endomembrane system organizationGO:00102561470.012
cell recognitionGO:0008037830.012
meiotic cell cycle processGO:1903046770.012
cell activation involved in immune responseGO:00022631260.012
macromolecule methylationGO:00434141200.012
carbohydrate derivative catabolic processGO:19011362310.012
peptidyl tyrosine modificationGO:00182121450.012
regulation of inflammatory responseGO:00507271470.012
cellular response to growth factor stimulusGO:00713631970.012
transmembrane transportGO:00550854120.012
mesenchymal cell differentiationGO:00487621070.012
regulation of secretionGO:00510462740.012
regulation of system processGO:00440572000.012
regulation of transmembrane transportGO:00347621280.012
leukocyte activation involved in immune responseGO:00023661260.012
sequestering of calcium ionGO:0051208180.012
inflammatory responseGO:00069542440.012
calcium ion transmembrane transportGO:0070588850.012
ion transmembrane transportGO:00342203610.012
regulation of cytokine productionGO:00018172660.012
organic hydroxy compound metabolic processGO:19016152030.012
positive regulation of immune effector processGO:00026991070.012
sequestering of metal ionGO:0051238190.012
mesoderm developmentGO:00074981000.011
regulation of leukocyte mediated immunityGO:00027031040.011
multicellular organismal signalingGO:0035637910.011
negative regulation of neuron deathGO:1901215980.011
retina morphogenesis in camera type eyeGO:0060042450.011
cellular metal ion homeostasisGO:00068751510.011
intracellular mrna localizationGO:000829840.011
adult behaviorGO:00305341350.011
regulation of bindingGO:00510981110.011
maintenance of locationGO:0051235890.011
nucleocytoplasmic transportGO:00069131390.011
response to radiationGO:00093141650.011
fat cell differentiationGO:00454441600.011
small molecule biosynthetic processGO:00442831320.011
skeletal muscle organ developmentGO:00605381630.011
regulation of mitotic cell cycleGO:00073461260.011
bmp signaling pathwayGO:0030509930.011
angiogenesisGO:00015252010.011
positive regulation of cell projection organizationGO:0031346950.011
cellular homeostasisGO:00197252400.011
regulation of mrna metabolic processGO:1903311430.011
ossificationGO:00015032160.011
forebrain developmentGO:00309003020.011
regulation of purine nucleotide catabolic processGO:00331211220.011
carbohydrate derivative biosynthetic processGO:19011371830.011
cell substrate adhesionGO:00315891300.011
regulation of cell cycle processGO:00105641600.011
purine ribonucleoside catabolic processGO:00461302050.011
microtubule cytoskeleton organizationGO:00002261570.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
positive regulation of leukocyte mediated immunityGO:0002705700.011
positive regulation of neuron projection developmentGO:0010976790.011
engulfment of apoptotic cellGO:004365230.011
pirna metabolic processGO:0034587120.011
coagulationGO:0050817780.011
gastrulationGO:00073691160.011
development of primary female sexual characteristicsGO:0046545730.011
chromatin modificationGO:00165681870.011
positive regulation of protein phosphorylationGO:00019342420.011
neuron projection guidanceGO:00974851410.011
digestive tract morphogenesisGO:00485461470.011
carboxylic acid biosynthetic processGO:0046394860.011
oogenesisGO:0048477560.010
binding of sperm to zona pellucidaGO:0007339340.010
negative regulation of intracellular signal transductionGO:19025321670.010
multi multicellular organism processGO:00447061090.010
neural tube formationGO:00018411080.010
purine ribonucleoside triphosphate catabolic processGO:00092071990.010
kidney epithelium developmentGO:00720731210.010
rho protein signal transductionGO:0007266320.010
nephron epithelium developmentGO:0072009920.010
regulation of ion transmembrane transportGO:00347651190.010
glycoprotein metabolic processGO:00091001160.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
locomotory behaviorGO:00076261950.010
sulfur compound metabolic processGO:00067901000.010
epithelial tube formationGO:00721751300.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.010
negative regulation of phosphorus metabolic processGO:00105631840.010
negative regulation of transferase activityGO:0051348850.010
muscle tissue developmentGO:00605373080.010

Plekhg4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.049
disease of anatomical entityDOID:700.049
sensory system diseaseDOID:005015500.027
eye and adnexa diseaseDOID:149200.017
eye diseaseDOID:561400.014
musculoskeletal system diseaseDOID:1700.012
retinal diseaseDOID:567900.012
retinal degenerationDOID:846600.012