Mus musculus

37 known processes

Pold1

polymerase (DNA directed), delta 1, catalytic subunit

(Aliases: 125kDa)

Pold1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:00062811070.969
dna metabolic processGO:00062593030.961
cellular response to dna damage stimulusGO:00069742070.960
dna recombinationGO:0006310920.901
base excision repairGO:000628490.818
meiotic cell cycle processGO:1903046770.639
meiotic nuclear divisionGO:00071261150.625
recombinational repairGO:0000725210.616
nuclear divisionGO:00002801580.538
chromatin organizationGO:00063252060.529
double strand break repairGO:0006302480.497
mitotic sister chromatid cohesionGO:000706410.487
response to radiationGO:00093141650.485
nuclear dna replicationGO:003326030.478
double strand break repair via homologous recombinationGO:0000724210.437
regulation of mitotic cell cycle phase transitionGO:1901990730.424
dna integrity checkpointGO:0031570280.396
chromatin silencingGO:0006342150.380
regulation of cell cycle processGO:00105641600.377
intra s dna damage checkpointGO:003157340.361
nucleobase containing small molecule metabolic processGO:00550863520.353
regulation of circadian sleep wake cycleGO:004274930.349
regulation of cell cycleGO:00517262810.335
mitotic cell cycle processGO:19030471590.308
chromosome segregationGO:0007059480.308
lateral inhibitionGO:004633110.293
dna dependent dna replicationGO:0006261240.292
somatic diversification of immune receptors via somatic mutationGO:000256680.277
telomere maintenanceGO:0000723190.275
purine nucleoside catabolic processGO:00061522050.274
circadian temperature homeostasisGO:006008620.269
heterochromatin organizationGO:007082840.264
organelle fissionGO:00482851700.263
double strand break repair via nonhomologous end joiningGO:0006303100.242
meiosis iGO:0007127600.237
mitotic cell cycleGO:00002781950.235
regulation of transcription by chromatin organizationGO:003440100.235
sister chromatid cohesionGO:0007062120.234
glycosyl compound metabolic processGO:19016572460.228
heterocycle catabolic processGO:00467002800.225
Yeast
nucleoside monophosphate metabolic processGO:0009123850.222
meiotic cell cycleGO:00513211220.200
reciprocal dna recombinationGO:0035825160.183
dna unwinding involved in dna replicationGO:000626850.176
purine containing compound metabolic processGO:00725213110.172
purine ribonucleoside monophosphate catabolic processGO:0009169570.172
dna damage checkpointGO:0000077260.169
cell cycle g2 m phase transitionGO:0044839200.168
somatic hypermutation of immunoglobulin genesGO:001644670.167
ribonucleoside triphosphate metabolic processGO:00091992200.165
purine ribonucleoside metabolic processGO:00461282410.160
gene silencingGO:0016458380.157
nucleoside triphosphate catabolic processGO:00091432050.156
regulation of circadian rhythmGO:0042752580.153
dna replicationGO:0006260520.150
negative regulation of mitotic cell cycleGO:0045930580.149
regulation of chromosome organizationGO:0033044830.148
purine ribonucleoside monophosphate metabolic processGO:0009167800.147
purine nucleotide metabolic processGO:00061633020.146
regulation of circadian sleep wake cycle sleepGO:004518730.141
nucleoside phosphate catabolic processGO:19012922220.140
mitotic nuclear divisionGO:0007067480.138
regulation of bindingGO:00510981110.133
negative regulation of molecular functionGO:00440922580.132
nucleoside metabolic processGO:00091162460.130
somatic recombination of immunoglobulin gene segmentsGO:0016447420.124
cellular amino acid metabolic processGO:00065201030.124
cell cycle checkpointGO:0000075470.121
nucleoside catabolic processGO:00091642060.120
negative regulation of gene expression epigeneticGO:0045814150.119
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.117
regulation of organelle organizationGO:00330432890.113
purine ribonucleoside triphosphate metabolic processGO:00092052200.112
purine nucleoside triphosphate catabolic processGO:00091462030.110
atp catabolic processGO:0006200550.106
ribonucleotide metabolic processGO:00092592910.106
nucleoside triphosphate metabolic processGO:00091412300.097
regulation of cellular catabolic processGO:00313292420.096
translesion synthesisGO:001998510.095
carbohydrate derivative catabolic processGO:19011362310.092
negative regulation of chromatin silencingGO:003193610.087
meiotic chromosome segregationGO:0045132190.085
purine ribonucleoside triphosphate catabolic processGO:00092071990.084
intrinsic apoptotic signaling pathwayGO:00971931320.083
dna duplex unwindingGO:003250870.083
organonitrogen compound catabolic processGO:19015652640.082
ribonucleoside catabolic processGO:00424542060.080
nucleoside monophosphate catabolic processGO:0009125590.078
organophosphate catabolic processGO:00464342320.077
mitotic sister chromatid segregationGO:0000070140.077
chromosome organization involved in meiosisGO:0070192390.075
ribonucleoside triphosphate catabolic processGO:00092031990.074
regulation of mitotic cell cycleGO:00073461260.072
ribonucleoside monophosphate metabolic processGO:0009161800.071
purine ribonucleotide catabolic processGO:00091542080.070
regulation of cell cycle phase transitionGO:1901987770.068
purine ribonucleoside catabolic processGO:00461302050.068
purine ribonucleotide metabolic processGO:00091502900.067
immunoglobulin productionGO:0002377730.067
dna geometric changeGO:003239270.066
rhythmic processGO:00485111740.065
glycosyl compound catabolic processGO:19016582060.064
sister chromatid segregationGO:0000819200.063
dna biosynthetic processGO:0071897220.063
Human Yeast
ribonucleoside metabolic processGO:00091192450.062
production of molecular mediator of immune responseGO:00024401030.062
regulation of hydrolase activityGO:00513362460.060
purine nucleoside triphosphate metabolic processGO:00091442260.060
meiotic sister chromatid segregationGO:004514460.059
cellular nitrogen compound catabolic processGO:00442702800.059
Yeast
development of primary sexual characteristicsGO:00451371430.059
respiratory tube developmentGO:00303231670.057
organic cyclic compound catabolic processGO:19013612950.055
Yeast
copulationGO:000762070.053
circadian rhythmGO:00076231140.050
multicellular organismal homeostasisGO:00488711640.050
protein processingGO:00164851630.049
regulation of chromatin silencingGO:003193520.047
locomotory behaviorGO:00076261950.046
gonad developmentGO:00084061410.045
meiosis iiGO:000713570.045
protein polymerizationGO:0051258570.044
somatic diversification of immunoglobulinsGO:0016445430.044
male meiosisGO:0007140370.044
dna replication initiationGO:000627050.043
regulation of chromosome segregationGO:0051983210.043
regulation of dna dependent dna replication initiationGO:003017430.042
purine nucleotide catabolic processGO:00061952110.042
negative regulation of cell cycleGO:00457861230.042
morphogenesis of a branching structureGO:00017632030.041
purine nucleoside monophosphate metabolic processGO:0009126810.040
cellular response to interleukin 4GO:0071353210.039
negative regulation of bindingGO:0051100390.039
purine nucleoside metabolic processGO:00422782410.037
response to light stimulusGO:00094161350.037
camera type eye developmentGO:00430102660.037
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.037
lung developmentGO:00303241640.036
dna endoreduplicationGO:004202340.036
signal transduction involved in dna damage checkpointGO:007242230.036
ribose phosphate metabolic processGO:00196932910.035
organelle localizationGO:00516401790.035
positive regulation of hydrolase activityGO:00513451480.035
somatic diversification of immune receptorsGO:0002200530.035
cell cycle g1 s phase transitionGO:0044843570.034
respiratory system developmentGO:00605411900.034
oogenesisGO:0048477560.034
regulation of cell cycle g2 m phase transitionGO:1902749100.034
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.033
dna conformation changeGO:0071103370.033
negative regulation of cell proliferationGO:00082852960.032
positive regulation of organelle organizationGO:00106381280.032
microtubule based processGO:00070172360.032
cellular response to abiotic stimulusGO:0071214560.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
nucleoside phosphate metabolic processGO:00067533380.031
negative regulation of cellular protein metabolic processGO:00322692470.031
positive regulation of mitotic sister chromatid separationGO:190197020.031
inner cell mass cell proliferationGO:0001833150.031
purine containing compound catabolic processGO:00725232130.031
response to inorganic substanceGO:0010035960.031
microtubule cytoskeleton organizationGO:00002261570.031
protein localization to chromosomeGO:003450260.031
digestive system developmentGO:00551232000.031
positive regulation of cellular amine metabolic processGO:003324050.030
adaptive immune responseGO:00022501550.030
ribonucleotide catabolic processGO:00092612080.030
nucleotide metabolic processGO:00091173320.029
histone modificationGO:00165701590.029
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.029
negative regulation of hydrolase activityGO:0051346710.028
endocytosisGO:00068971680.028
Worm
apoptotic signaling pathwayGO:00971903060.028
positive regulation of transferase activityGO:00513471670.028
purine nucleoside monophosphate catabolic processGO:0009128580.028
morphogenesis of a branching epitheliumGO:00611381930.028
cellular response to cytokine stimulusGO:00713451890.028
negative regulation of nucleoside metabolic processGO:0045978110.028
rhythmic behaviorGO:0007622150.027
regulation of transferase activityGO:00513382630.027
protein localization to chromatinGO:007116830.027
positive regulation of protein modification processGO:00314012990.027
cell divisionGO:00513011200.027
Worm
regulation of nuclear cell cycle dna replicationGO:003326220.026
female gamete generationGO:0007292740.026
cellular protein complex assemblyGO:00436231160.026
mitotic chromosome condensationGO:000707610.026
anatomical structure homeostasisGO:00602491450.025
g2 m transition of mitotic cell cycleGO:0000086200.025
cellular ketone metabolic processGO:0042180840.025
epithelial tube morphogenesisGO:00605623030.025
ribonucleoside monophosphate catabolic processGO:0009158570.025
atp metabolic processGO:0046034750.025
b cell activationGO:00421131610.024
mating behaviorGO:0007617200.024
snrna metabolic processGO:001607310.024
negative regulation of gene silencingGO:006096920.024
negative regulation of protein modification processGO:00314001630.024
negative regulation of dna bindingGO:0043392200.024
regulation of anatomical structure sizeGO:00900661780.024
negative regulation of cell cycle phase transitionGO:1901988480.024
nucleobase biosynthetic processGO:004611230.024
response to testosteroneGO:003357430.023
membrane organizationGO:00610242450.023
protein dna complex subunit organizationGO:0071824280.023
aromatic compound catabolic processGO:00194392860.023
Yeast
alpha amino acid metabolic processGO:1901605590.023
digestive tract developmentGO:00485651900.023
positive regulation of cell cycle phase transitionGO:1901989170.023
regulation of dna dependent dna replicationGO:009032980.023
multicellular organismal agingGO:0010259240.023
organonitrogen compound biosynthetic processGO:19015661920.022
nucleotide catabolic processGO:00091662170.022
regulation of dna bindingGO:0051101390.022
positive regulation of protein phosphorylationGO:00019342420.022
negative regulation of purine nucleotide metabolic processGO:1900543160.022
membrane disassemblyGO:003039710.022
covalent chromatin modificationGO:00165691630.022
male gamete generationGO:00482322850.021
cellular amine metabolic processGO:0044106440.021
regulation of protein localizationGO:00328802310.021
positive regulation of mitotic metaphase anaphase transitionGO:004584220.021
histone methylationGO:0016571710.021
regulation of apoptotic signaling pathwayGO:20012331970.021
b cell activation involved in immune responseGO:0002312500.020
digestive tract morphogenesisGO:00485461470.020
lymphocyte mediated immunityGO:00024491390.020
regulation of protein kinase activityGO:00458592320.020
regulation of nucleoside metabolic processGO:00091181300.020
immunoglobulin mediated immune responseGO:0016064690.020
leukocyte activation involved in immune responseGO:00023661260.020
regulation of cellular amino acid metabolic processGO:000652150.020
stem cell proliferationGO:00720891170.019
nucleus organizationGO:0006997450.019
gliogenesisGO:00420631410.019
response to organonitrogen compoundGO:00102432460.019
amine metabolic processGO:0009308450.019
protein localization to organelleGO:00333651850.019
pharynx developmentGO:006046510.019
cofactor metabolic processGO:0051186800.018
branching morphogenesis of an epithelial tubeGO:00487541590.018
intracellular protein transportGO:00068862040.018
regulation of cysteine type endopeptidase activityGO:2000116650.018
circadian behaviorGO:0048512130.018
response to lipopolysaccharideGO:00324961280.018
protein maturationGO:00516041760.018
response to interleukin 4GO:0070670230.017
negative regulation of cell developmentGO:00107211690.017
negative regulation of mitotic cell cycle phase transitionGO:1901991450.017
actin filament polymerizationGO:0030041440.017
regulation of cytokine productionGO:00018172660.017
leukocyte mediated immunityGO:00024431740.017
positive regulation of cell deathGO:00109422240.017
dna replication checkpointGO:000007620.017
maintenance of epithelial cell apical basal polarityGO:004519920.016
oxidation reduction processGO:00551143420.016
regulation of meiotic cell cycleGO:0051445340.016
response to growth factorGO:00708481980.016
positive regulation of fibroblast proliferationGO:0048146200.016
peptidyl amino acid modificationGO:00181933360.016
l serine metabolic processGO:000656320.016
lymphocyte activation involved in immune responseGO:0002285930.016
regulation of transcription regulatory region dna bindingGO:200067790.016
regulation of g2 m transition of mitotic cell cycleGO:0010389100.016
macromolecule catabolic processGO:00090572810.016
Yeast
multi organism behaviorGO:0051705620.015
regulation of dna replicationGO:0006275170.015
glial cell differentiationGO:00100011310.015
dna packagingGO:0006323300.015
telomere maintenance via telomere lengtheningGO:001083340.015
protein modification by small protein conjugationGO:00324461870.015
circadian sleep wake cycleGO:004274550.015
snrna processingGO:001618010.015
telomere maintenance via telomeraseGO:000700410.015
gland developmentGO:00487323300.015
cellular response to transforming growth factor beta stimulusGO:0071560880.015
cellular response to growth factor stimulusGO:00713631970.015
cellular response to inorganic substanceGO:0071241370.015
regulation of cellular amine metabolic processGO:0033238200.015
positive regulation of chromosome organizationGO:2001252330.014
response to ionizing radiationGO:0010212420.014
regulation of lymphocyte proliferationGO:00506701170.014
immune effector processGO:00022523210.014
regulation of proteolysisGO:00301621640.014
negative regulation of phosphorylationGO:00423261660.014
regulation of cell divisionGO:0051302760.014
negative regulation of transcription regulatory region dna bindingGO:200067870.014
cell activation involved in immune responseGO:00022631260.014
negative regulation of phosphate metabolic processGO:00459361840.014
temperature homeostasisGO:0001659260.014
response to transforming growth factor betaGO:0071559880.014
antimicrobial peptide biosynthetic processGO:000277720.014
peptidyl lysine modificationGO:0018205770.013
isotype switchingGO:0045190360.013
positive regulation of nervous system developmentGO:00519622210.013
cell cell signaling involved in cell fate commitmentGO:0045168350.013
peptidyl serine phosphorylationGO:0018105740.013
regulation of cellular ketone metabolic processGO:0010565660.013
nuclear envelope organizationGO:0006998110.013
negative regulation of protein metabolic processGO:00512482820.013
spermatogenesisGO:00072832840.013
regulation of nucleotide catabolic processGO:00308111220.013
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.013
response to temperature stimulusGO:0009266550.013
blastocyst developmentGO:0001824800.013
regulation of secretion by cellGO:19035302490.013
negative regulation of histone h3 k9 methylationGO:005157340.013
non recombinational repairGO:0000726100.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.012
cellular response to hormone stimulusGO:00328701500.012
matingGO:0007618270.012
b cell mediated immunityGO:0019724710.012
cell maturationGO:00484691270.012
negative regulation of organelle organizationGO:0010639900.012
amide transportGO:00428861380.012
positive regulation of programmed cell deathGO:00430682180.012
protein ubiquitinationGO:00165671710.012
mitotic cell cycle checkpointGO:0007093310.012
cellular homeostasisGO:00197252400.012
cellular response to radiationGO:0071478280.012
cytokine productionGO:00018163190.012
organism emergence from protective structureGO:007168440.012
Worm
g1 s transition of mitotic cell cycleGO:0000082570.012
regulation of actin polymerization or depolymerizationGO:0008064450.012
pyrimidine nucleobase metabolic processGO:000620630.012
positive regulation of apoptotic processGO:00430652170.012
endomembrane system organizationGO:00102561470.012
response to oxidative stressGO:00069791230.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
divalent metal ion transportGO:00708381720.011
transmembrane transportGO:00550854120.011
positive regulation of cellular catabolic processGO:00313311480.011
protein modification by small protein conjugation or removalGO:00706472070.011
spindle assembly involved in female meiosisGO:000705630.011
response to reactive oxygen speciesGO:0000302560.011
regulation of chromatin modificationGO:1903308570.011
negative regulation of kinase activityGO:0033673810.011
gene conversionGO:003582220.011
positive regulation of histone modificationGO:0031058280.011
regulation of purine nucleotide metabolic processGO:19005421690.011
locomotor rhythmGO:004547580.011
hematopoietic stem cell proliferationGO:0071425130.011
regulation of atp metabolic processGO:1903578170.011
tricarboxylic acid metabolic processGO:007235050.011
positive regulation of chromosome segregationGO:005198440.011
innate immune responseGO:00450871570.011
positive regulation of metaphase anaphase transition of cell cycleGO:190210120.011
histone lysine methylationGO:0034968500.011
positive regulation of immune effector processGO:00026991070.011
mitotic g1 dna damage checkpointGO:003157140.010
chromosome separationGO:0051304140.010
divalent inorganic cation transportGO:00725111780.010
sensory organ morphogenesisGO:00905962420.010
regulation of multi organism processGO:00439001110.010
genitalia developmentGO:0048806370.010
regulation of homeostatic processGO:00328441820.010
regulation of sister chromatid cohesionGO:000706350.010
nucleobase metabolic processGO:000911270.010
multi multicellular organism processGO:00447061090.010
cellular response to organonitrogen compoundGO:00714171450.010

Pold1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.266
Human
disease of cellular proliferationDOID:1456600.266
Human
inherited metabolic disorderDOID:65500.082
disease of metabolismDOID:001466700.082
organ system cancerDOID:005068600.054
Human
large intestine cancerDOID:567200.028
Human
gastrointestinal system cancerDOID:311900.028
Human
intestinal cancerDOID:1015500.028
Human
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
central nervous system diseaseDOID:33100.020
neurodegenerative diseaseDOID:128900.011