Mus musculus

225 known processes

Itch

itchy, E3 ubiquitin protein ligase

(Aliases: C230047C07Rik,mKIAA4011,8030492O04Rik,6720481N21Rik,KIAA4011,A130065M08,AIP4)

Itch biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ripoptosome assembly involved in necroptotic processGO:190102660.981
necroptotic processGO:0070266210.901
negative regulation of nf kappab transcription factor activityGO:0032088150.740
programmed necrotic cell deathGO:0097300280.726
extrinsic apoptotic signaling pathwayGO:00971911260.694
regulation of sequence specific dna binding transcription factor activityGO:00510901060.672
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.634
necrotic cell deathGO:0070265300.579
regulation of necroptotic processGO:0060544100.565
negative regulation of necroptotic processGO:006054690.388
regulation of apoptotic signaling pathwayGO:20012331970.386
negative regulation of molecular functionGO:00440922580.381
negative regulation of necrotic cell deathGO:0060547110.360
stress activated protein kinase signaling cascadeGO:0031098810.317
i kappab kinase nf kappab signalingGO:0007249850.282
macromolecule catabolic processGO:00090572810.263
positive regulation of cytokine productionGO:00018191740.223
small gtpase mediated signal transductionGO:0007264970.217
protein modification by small protein removalGO:0070646210.206
ripoptosome assemblyGO:009734360.193
muscle cell proliferationGO:0033002520.188
response to interleukin 12GO:007067120.184
protein catabolic processGO:00301632210.178
apoptotic signaling pathwayGO:00971903060.173
cellular protein catabolic processGO:00442571550.172
modification dependent macromolecule catabolic processGO:00436321330.170
t cell activationGO:00421102890.168
activation of immune responseGO:00022531380.163
positive regulation of protein phosphorylationGO:00019342420.163
protein modification by small protein conjugation or removalGO:00706472070.160
ras protein signal transductionGO:0007265770.158
proteolysis involved in cellular protein catabolic processGO:00516031470.153
rho protein signal transductionGO:0007266320.151
t cell receptor signaling pathwayGO:0050852460.141
regulation of t cell proliferationGO:0042129920.137
regulation of lymphocyte differentiationGO:00456191070.136
activation of nf kappab inducing kinase activityGO:000725040.134
lymphocyte differentiationGO:00300982420.133
negative regulation of lymphocyte activationGO:0051250910.128
positive regulation of protein modification processGO:00314012990.127
canonical wnt signaling pathwayGO:00600701300.125
alpha beta t cell activationGO:0046631910.121
negative regulation of cell proliferationGO:00082852960.120
positive regulation of nf kappab transcription factor activityGO:0051092300.116
t cell proliferationGO:00420981200.115
pattern recognition receptor signaling pathwayGO:0002221470.113
regulation of transferase activityGO:00513382630.112
myeloid leukocyte differentiationGO:00025731190.111
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.110
regulation of lymphocyte activationGO:00512492400.108
regulation of interferon gamma productionGO:0032649570.107
lymphocyte proliferationGO:00466511640.106
nik nf kappab signalingGO:0038061140.104
striated muscle atrophyGO:001489120.104
cell type specific apoptotic processGO:00972852680.103
regulation of cd8 positive alpha beta cytotoxic t cell extravasationGO:200045220.100
negative regulation of intracellular signal transductionGO:19025321670.099
immune response regulating signaling pathwayGO:00027641250.099
regulation of protein localizationGO:00328802310.099
Yeast Fly
epithelial tube morphogenesisGO:00605623030.098
interleukin 8 productionGO:003263740.096
actin cytoskeleton organizationGO:00300362200.094
Yeast
tumor necrosis factor superfamily cytokine productionGO:0071706510.093
lymphocyte mediated immunityGO:00024491390.093
t cell differentiationGO:00302171740.093
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.092
response to organic cyclic compoundGO:00140701980.091
protein modification by small protein conjugationGO:00324461870.090
regulation of interleukin 2 productionGO:0032663280.090
leukocyte mediated immunityGO:00024431740.088
protein import into nucleusGO:0006606950.085
negative regulation of apoptotic signaling pathwayGO:20012341040.085
positive regulation of hydrolase activityGO:00513451480.084
regulation of cell migrationGO:00303342190.084
regulation of cell activationGO:00508652890.084
jnk cascadeGO:0007254720.083
regulation of interleukin 8 productionGO:003267730.083
cdc42 protein signal transductionGO:003248800.083
microtubule cytoskeleton organizationGO:00002261570.083
protein deacetylationGO:0006476320.082
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.081
organonitrogen compound biosynthetic processGO:19015661920.080
muscle atrophyGO:001488930.080
negative regulation of canonical wnt signaling pathwayGO:0090090510.080
regulation of protein serine threonine kinase activityGO:00719001570.077
immune effector processGO:00022523210.077
leukocyte differentiationGO:00025213420.076
gtp metabolic processGO:00460391440.076
cellular response to lipidGO:00713961450.075
nucleocytoplasmic transportGO:00069131390.074
Yeast
cellular macromolecule catabolic processGO:00442652060.073
positive regulation of mapk cascadeGO:00434101700.072
macromolecule deacylationGO:0098732370.072
immune response activating signal transductionGO:00027571160.072
tube formationGO:00351481400.070
regulation of endopeptidase activityGO:0052548890.069
regulation of protein transportGO:00512231630.068
ubiquitin dependent protein catabolic processGO:00065111290.067
homeostasis of number of cellsGO:00488722100.067
respiratory tube developmentGO:00303231670.066
positive regulation of programmed cell deathGO:00430682180.066
digestive system developmentGO:00551232000.065
response to oxidative stressGO:00069791230.065
regulation of adaptive immune responseGO:0002819900.065
protein localization to organelleGO:00333651850.064
regulation of lymphocyte mediated immunityGO:0002706840.064
negative regulation of immune system processGO:00026832090.064
positive regulation of cellular amine metabolic processGO:003324050.063
regulation of protein maturationGO:1903317960.062
acylglycerol homeostasisGO:0055090160.062
heart morphogenesisGO:00030071780.062
Mouse
regulation of rho protein signal transductionGO:0035023710.062
positive regulation of protein kinase activityGO:00458601440.061
positive regulation of rac gtpase activityGO:0032855140.061
morphogenesis of embryonic epitheliumGO:00163311590.061
regulation of t cell differentiationGO:0045580830.061
intracellular protein transportGO:00068862040.061
antigen receptor mediated signaling pathwayGO:0050851640.061
leukocyte activation involved in immune responseGO:00023661260.061
regulation of hydrolase activityGO:00513362460.060
cellular homeostasisGO:00197252400.060
digestive tract morphogenesisGO:00485461470.059
myeloid cell differentiationGO:00300992330.058
regulation of reactive oxygen species metabolic processGO:2000377400.058
regulation of leukocyte proliferationGO:00706631210.057
muscle tissue developmentGO:00605373080.057
positive regulation of apoptotic signaling pathwayGO:2001235950.057
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.056
regulation of transmembrane transportGO:00347621280.055
Mouse
regulation of cellular response to stressGO:00801351590.055
positive regulation of gtpase activityGO:0043547850.055
amine metabolic processGO:0009308450.054
cytokine productionGO:00018163190.054
organelle localizationGO:00516401790.054
Yeast
cellular response to peptidoglycanGO:007122440.054
positive regulation of immature t cell proliferationGO:003309140.053
positive regulation of production of molecular mediator of immune responseGO:0002702450.052
positive regulation of macroautophagyGO:001623930.052
activation of innate immune responseGO:0002218560.052
mitotic cell cycleGO:00002781950.051
positive regulation of lymphocyte mediated immunityGO:0002708620.050
anion transportGO:00068201770.050
negative regulation of protein processingGO:0010955790.050
oxidation reduction processGO:00551143420.049
purine ribonucleoside catabolic processGO:00461302050.049
mitotic cell cycle processGO:19030471590.049
leukocyte proliferationGO:00706611720.049
positive regulation of kinase activityGO:00336741550.048
response to reactive oxygen speciesGO:0000302560.048
regulation of mapk cascadeGO:00434082480.048
regulation of myotube differentiationGO:0010830620.047
regulation of necrotic cell deathGO:0010939130.047
regulation of production of molecular mediator of immune responseGO:0002700650.047
positive regulation of protein serine threonine kinase activityGO:00719021060.047
positive regulation of cellular amino acid metabolic processGO:004576430.047
muscle cell differentiationGO:00426922610.046
organelle assemblyGO:00709251770.046
mapk cascadeGO:00001652810.046
ear developmentGO:00435832000.046
positive regulation of interleukin 8 productionGO:003275720.045
positive regulation of map kinase activityGO:0043406840.045
protein localization to nucleusGO:00345041210.044
cellular response to nitric oxideGO:007173240.044
nuclear importGO:0051170950.044
negative regulation of cell activationGO:00508661110.044
skeletal muscle adaptationGO:0043501160.043
regulation of cell cycleGO:00517262810.043
cellular response to oxidative stressGO:0034599760.043
striated muscle tissue developmentGO:00147062930.042
heterocycle catabolic processGO:00467002800.042
cellular amino acid metabolic processGO:00065201030.042
negative regulation of endopeptidase activityGO:0010951440.041
cytokine metabolic processGO:0042107710.041
negative regulation of wnt signaling pathwayGO:0030178730.040
negative regulation of cellular component organizationGO:00511291940.040
nitrogen compound transportGO:00717052710.040
Yeast
lipid homeostasisGO:0055088630.040
t helper cell differentiationGO:0042093280.040
regulation of alpha beta t cell activationGO:0046634530.040
regulation of microtubule based processGO:0032886520.040
myotube differentiationGO:00149021050.039
regulation of mitotic cell cycleGO:00073461260.039
regulation of organelle organizationGO:00330432890.039
Yeast
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.038
syncytium formation by plasma membrane fusionGO:0000768420.038
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.038
positive regulation of stress activated mapk cascadeGO:0032874480.038
muscle system processGO:00030121410.038
embryonic organ morphogenesisGO:00485622760.038
response to lipopolysaccharideGO:00324961280.038
muscle cell developmentGO:00550011330.037
regulation of t cell extravasationGO:200040730.037
striated muscle adaptationGO:0014888260.037
positive regulation of lymphocyte activationGO:00512511400.037
skeletal myofibril assemblyGO:001486640.036
immune response regulating cell surface receptor signaling pathwayGO:0002768800.036
neural tube developmentGO:00219151600.035
response to molecule of bacterial originGO:00022371430.035
histone modificationGO:00165701590.035
positive regulation of innate immune responseGO:0045089800.035
skeletal muscle organ developmentGO:00605381630.034
regulation of cytoskeleton organizationGO:00514931220.034
Yeast
cellular nitrogen compound catabolic processGO:00442702800.034
embryonic epithelial tube formationGO:00018381300.034
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.034
positive regulation of adaptive immune responseGO:0002821610.034
positive regulation of apoptotic processGO:00430652170.034
cellular chemical homeostasisGO:00550822150.034
cellular ion homeostasisGO:00068731650.033
regulation of cellular ketone metabolic processGO:0010565660.033
Yeast
regulation of establishment of protein localizationGO:00702011810.033
cytoplasmic transportGO:00164822340.033
Yeast
cell activation involved in immune responseGO:00022631260.032
dna repairGO:00062811070.032
regulation of cell motilityGO:20001452360.032
microtubule based processGO:00070172360.032
negative regulation of lymphocyte differentiationGO:0045620320.032
epithelial tube formationGO:00721751300.032
epithelial cell proliferationGO:00506731740.032
syncytium formationGO:0006949430.031
establishment of protein localization to organelleGO:00725941180.031
inorganic cation transmembrane transportGO:00986622070.031
Mouse
retrograde transport endosome to golgiGO:004214720.031
regulation of nucleotide catabolic processGO:00308111220.031
positive regulation of t cell activationGO:00508701010.031
digestive tract developmentGO:00485651900.031
positive regulation of ras gtpase activityGO:0032320650.031
nuclear transportGO:00511691390.031
Yeast
cd8 positive alpha beta t cell extravasationGO:003569730.031
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.031
protein deacylationGO:0035601360.031
sensory organ morphogenesisGO:00905962420.031
interleukin 2 productionGO:0032623330.030
organelle fissionGO:00482851700.030
regulation of protein import into nucleusGO:0042306520.030
transmembrane transportGO:00550854120.030
Mouse
positive regulation of cell deathGO:00109422240.030
erk1 and erk2 cascadeGO:0070371770.030
regulation of protein processingGO:0070613960.030
amide transportGO:00428861380.030
regulation of microtubule cytoskeleton organizationGO:0070507370.030
response to organonitrogen compoundGO:00102432460.030
protein maturationGO:00516041760.030
regulation of syncytium formation by plasma membrane fusionGO:0060142230.030
gland developmentGO:00487323300.029
cellular component assembly involved in morphogenesisGO:00109271390.029
Yeast
cellular protein complex assemblyGO:00436231160.029
limb developmentGO:00601731660.029
ribonucleoside triphosphate catabolic processGO:00092031990.029
tissue homeostasisGO:00018941150.029
lymphocyte activation involved in immune responseGO:0002285930.029
regulation of erk1 and erk2 cascadeGO:0070372710.029
leukocyte migrationGO:00509001240.029
protein processingGO:00164851630.029
cd4 positive alpha beta t cell activationGO:0035710450.029
synaptic transmissionGO:00072683290.029
Mouse
defense response to other organismGO:00985421970.029
regulation of ion transportGO:00432692150.028
Mouse
regulation of peptide transportGO:0090087910.028
regulation of cytokine productionGO:00018172660.028
negative regulation of leukocyte differentiationGO:1902106510.028
regulation of gtp catabolic processGO:00331241130.028
regulation of stress activated mapk cascadeGO:0032872690.028
purine ribonucleotide catabolic processGO:00091542080.028
regulation of striated muscle cell differentiationGO:0051153810.028
extracellular matrix organizationGO:00301981470.028
regulation of map kinase activityGO:00434051200.028
guanosine containing compound metabolic processGO:19010681440.028
cytokine production involved in immune responseGO:0002367340.028
negative regulation of endothelial cell migrationGO:001059640.028
regulation of purine nucleotide catabolic processGO:00331211220.027
regulation of cellular amino acid metabolic processGO:000652150.027
wnt signaling pathwayGO:00160551880.027
negative regulation of muscle cell differentiationGO:0051148330.027
muscle adaptationGO:0043500390.027
protein polyubiquitinationGO:0000209330.027
cellular metal ion homeostasisGO:00068751510.027
cellular divalent inorganic cation homeostasisGO:00725031270.027
regulation of defense responseGO:00313472330.027
negative regulation of peptidase activityGO:0010466460.027
positive regulation of endocytosisGO:0045807420.027
Yeast
interleukin 1 mediated signaling pathwayGO:007049840.027
forebrain developmentGO:00309003020.027
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.027
camera type eye developmentGO:00430102660.026
cation transmembrane transportGO:00986552660.026
Mouse
regulation of ras protein signal transductionGO:00465781140.026
cellular response to organonitrogen compoundGO:00714171450.026
negative regulation of protein transportGO:0051224460.026
lipopolysaccharide mediated signaling pathwayGO:0031663250.026
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.026
interferon gamma productionGO:0032609670.026
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.026
t cell mediated immunityGO:0002456500.026
purine containing compound catabolic processGO:00725232130.026
t cell extravasationGO:007268340.026
blood circulationGO:00080151950.025
Mouse
lymphocyte homeostasisGO:0002260640.025
regulation of lymphocyte proliferationGO:00506701170.025
regulation of interleukin 6 productionGO:0032675550.025
aromatic compound catabolic processGO:00194392860.025
cellular response to lipopolysaccharideGO:0071222770.025
regulation of myeloid leukocyte differentiationGO:0002761580.025
purine ribonucleoside metabolic processGO:00461282410.025
ameboidal type cell migrationGO:00016671280.025
ear morphogenesisGO:00424711180.025
male gamete generationGO:00482322850.025
regulation of myeloid cell differentiationGO:0045637960.025
lymph node developmentGO:0048535180.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.025
Mouse
cellular ketone metabolic processGO:0042180840.025
Yeast
purine ribonucleotide metabolic processGO:00091502900.025
stress activated mapk cascadeGO:0051403800.025
regulation of b cell activationGO:0050864810.024
cation homeostasisGO:00550802120.024
regulation of t cell mediated immunityGO:0002709340.024
regulation of nucleocytoplasmic transportGO:0046822730.024
Yeast
myeloid dendritic cell activationGO:0001773250.024
alpha beta t cell differentiationGO:0046632690.024
positive regulation of interleukin 6 productionGO:0032755370.024
primary neural tube formationGO:0014020950.024
purine nucleotide metabolic processGO:00061633020.024
regulation of rho gtpase activityGO:0032319580.024
purine nucleoside triphosphate metabolic processGO:00091442260.024
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.024
negative regulation of hydrolase activityGO:0051346710.024
lateral inhibitionGO:004633110.024
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.024
Yeast Mouse
negative regulation of proteolysisGO:0045861740.023
cell adhesionGO:00071553290.023
regulation of cellular catabolic processGO:00313292420.023
Yeast
extracellular structure organizationGO:00430621480.023
divalent inorganic cation homeostasisGO:00725071380.023
negative regulation of cellular protein metabolic processGO:00322692470.023
regulation of leukocyte differentiationGO:19021051590.023
memoryGO:0007613580.023
intrinsic apoptotic signaling pathwayGO:00971931320.023
positive regulation of myeloid leukocyte differentiationGO:0002763260.022
type i interferon productionGO:0032606290.022
single organism nuclear importGO:1902593950.022
regulation of canonical wnt signaling pathwayGO:0060828820.022
organic hydroxy compound transportGO:0015850930.022
inner ear morphogenesisGO:00424721010.022
organic hydroxy compound biosynthetic processGO:1901617770.022
Yeast
membrane organizationGO:00610242450.022
positive regulation of interferon gamma productionGO:0032729390.022
positive regulation of erk1 and erk2 cascadeGO:0070374470.022
response to inorganic substanceGO:0010035960.022
positive regulation of jnk cascadeGO:0046330460.022
locomotory behaviorGO:00076261950.022
modification dependent protein catabolic processGO:00199411330.022
tube closureGO:0060606910.022
nucleoside triphosphate metabolic processGO:00091412300.022
regulation of intracellular transportGO:00323861590.022
Yeast
protein k63 linked deubiquitinationGO:007053610.021
cellular response to biotic stimulusGO:0071216920.021
placenta developmentGO:00018901400.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.021
endocytosisGO:00068971680.021
Yeast Fly
osteoclast differentiationGO:0030316620.021
positive regulation of leukocyte mediated immunityGO:0002705700.021
interleukin 6 productionGO:0032635580.021
bone resorptionGO:0045453380.021
lung developmentGO:00303241640.021
positive regulation of proteolysisGO:0045862850.021
Yeast
purine ribonucleoside triphosphate metabolic processGO:00092052200.021
telencephalon developmentGO:00215371860.021
purine nucleoside metabolic processGO:00422782410.021
positive regulation of cellular catabolic processGO:00313311480.021
Yeast
appendage developmentGO:00487361660.021
Fly
positive regulation of transferase activityGO:00513471670.021
nucleoside phosphate metabolic processGO:00067533380.021
defense response to bacteriumGO:00427421190.021
regenerationGO:0031099380.021
positive regulation of rho gtpase activityGO:0032321410.020
reactive oxygen species metabolic processGO:0072593840.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.020
multicellular organismal homeostasisGO:00488711640.020
ribose phosphate metabolic processGO:00196932910.020
negative regulation of endothelial cell differentiationGO:004560220.020
regulation of protein kinase activityGO:00458592320.020
cell divisionGO:00513011200.020
regulation of system processGO:00440572000.020
neural tube closureGO:0001843900.020
kidney developmentGO:00018222130.020
negative regulation of protein metabolic processGO:00512482820.020
wound healingGO:00420601570.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
positive regulation of leukocyte proliferationGO:0070665730.020
regulation of tumor necrosis factor productionGO:0032680490.020
nuclear divisionGO:00002801580.020
ribonucleoside triphosphate metabolic processGO:00091992200.020
embryonic appendage morphogenesisGO:00351131260.020
regulation of cysteine type endopeptidase activityGO:2000116650.020
respiratory system developmentGO:00605411900.020
regulation of nucleoside metabolic processGO:00091181300.020
cellular response to external stimulusGO:0071496880.020
positive regulation of leukocyte differentiationGO:1902107860.020
actin filament organizationGO:00070151130.019
innate immune responseGO:00450871570.019
bone remodelingGO:0046849530.019
nucleobase containing small molecule metabolic processGO:00550863520.019
tumor necrosis factor productionGO:0032640500.019
tissue remodelingGO:00487711020.019
inorganic ion transmembrane transportGO:00986602340.019
Mouse
regulation of jnk cascadeGO:0046328620.019
regulation of leukocyte mediated immunityGO:00027031040.019
signal transduction in absence of ligandGO:0038034550.019
sensory perceptionGO:00076002450.019
regulation of organ morphogenesisGO:20000271440.018
organic cyclic compound catabolic processGO:19013612950.018
regulation of t cell activationGO:00508631700.018
protein ubiquitinationGO:00165671710.018
organic hydroxy compound metabolic processGO:19016152030.018
Yeast
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041220.018
calcium ion homeostasisGO:00550741270.018
protein oligomerizationGO:0051259670.018
neural tube formationGO:00018411080.018
negative regulation of t cell differentiationGO:0045581230.018
positive regulation of necrotic cell deathGO:001094010.018
appendage morphogenesisGO:00351071490.018
Fly
protein targetingGO:00066051430.018
regulation of secretion by cellGO:19035302490.018
response to unfolded proteinGO:0006986210.017
glycosyl compound metabolic processGO:19016572460.017
nucleoside monophosphate metabolic processGO:0009123850.017
circulatory system processGO:00030131970.017
Mouse
negative regulation of cytokine productionGO:0001818840.017
nucleoside metabolic processGO:00091162460.017
negative regulation of protein maturationGO:1903318790.017
negative regulation of t cell proliferationGO:0042130380.017
anatomical structure homeostasisGO:00602491450.017
transmission of nerve impulseGO:0019226760.017
negative regulation of signal transduction in absence of ligandGO:1901099160.017
renal system developmentGO:00720012250.017
cell junction organizationGO:0034330770.017
Mouse
respiratory gaseous exchangeGO:0007585430.017
actomyosin structure organizationGO:0031032560.017
ribonucleoside metabolic processGO:00091192450.017
positive regulation of purine nucleotide metabolic processGO:19005441140.016
covalent chromatin modificationGO:00165691630.016
embryonic placenta developmentGO:0001892980.016
response to uvGO:0009411440.016
Yeast
regulation of peptidase activityGO:0052547960.016
response to starvationGO:0042594650.016
hematopoietic progenitor cell differentiationGO:00022441430.016
ion transmembrane transportGO:00342203610.016
Mouse
regulation of nik nf kappab signalingGO:1901222100.016
synaptic vesicle localizationGO:0097479590.016
palate developmentGO:0060021760.016
regulation of cytoplasmic transportGO:19036491120.016
Yeast
regulation of ras gtpase activityGO:0032318880.016
positive regulation of defense responseGO:00313491240.016
negative regulation of striated muscle cell differentiationGO:0051154140.016
neural precursor cell proliferationGO:00613511210.016
posttranscriptional regulation of gene expressionGO:00106081550.016
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.016
humoral immune responseGO:0006959570.016
divalent metal ion transportGO:00708381720.016
protein alkylationGO:0008213810.016
regulation of homeostatic processGO:00328441820.016
pharynx developmentGO:006046510.016
cognitionGO:00508901490.016
lipid localizationGO:00108761260.016
Worm Fly
peptide transportGO:00158331330.016
leukocyte homeostasisGO:0001776790.015
neuron deathGO:00709971540.015
glycoprotein metabolic processGO:00091001160.015
maintenance of locationGO:0051235890.015
Worm Fly
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.015
skeletal system developmentGO:00015013560.015
establishment of vesicle localizationGO:0051650810.015
protein deubiquitinationGO:0016579190.015
negative regulation of nucleocytoplasmic transportGO:0046823230.015
cellular response to topologically incorrect proteinGO:0035967250.015
regulation of alpha beta t cell proliferationGO:0046640180.015
regulation of alpha beta t cell differentiationGO:0046637350.015
organonitrogen compound catabolic processGO:19015652640.015
cd4 positive alpha beta t cell differentiationGO:0043367410.015
regulation of endocytosisGO:0030100690.015
Yeast
endoplasmic reticulum unfolded protein responseGO:0030968190.015
regulation of protein deacetylationGO:0090311170.015

Itch disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.056
disease of cellular proliferationDOID:1456600.056
organ system cancerDOID:005068600.056
disease of metabolismDOID:001466700.038
disease of anatomical entityDOID:700.024
connective tissue diseaseDOID:6500.024
musculoskeletal system diseaseDOID:1700.024
immune system cancerDOID:006008300.021
inherited metabolic disorderDOID:65500.019
bone development diseaseDOID:008000600.019
bone diseaseDOID:008000100.019
immune system diseaseDOID:291400.016
hematopoietic system diseaseDOID:7400.016