Mus musculus

182 known processes

Ikzf1

IKAROS family zinc finger 1

(Aliases: 5832432G11Rik,hlk-1,LyF-1,Ikaros,mKIAA4227,Znfn1a1,KIAA4227,Zfpn1a1)

Ikzf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of b cell differentiationGO:0045577231.000
t cell differentiation in thymusGO:0033077771.000
Zebrafish
lymphocyte differentiationGO:00300982421.000
b cell differentiationGO:0030183781.000
alpha beta t cell differentiationGO:0046632691.000
b cell activationGO:00421131611.000
t cell differentiationGO:00302171741.000
positive regulation of gamma delta t cell differentiationGO:004558860.999
t cell activationGO:00421102890.999
regulation of cell activationGO:00508652890.999
t cell receptor signaling pathwayGO:0050852460.999
positive regulation of t cell activationGO:00508701010.999
t cell selectionGO:0045058340.999
regulation of b cell activationGO:0050864810.999
cell activation involved in immune responseGO:00022631260.999
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.999
positive regulation of cell activationGO:00508671580.999
leukocyte differentiationGO:00025213420.999
immune response activating signal transductionGO:00027571160.998
v d j recombinationGO:0033151140.998
somatic cell dna recombinationGO:0016444510.998
immune response activating cell surface receptor signaling pathwayGO:0002429720.998
regulation of myeloid leukocyte differentiationGO:0002761580.998
dna recombinationGO:0006310920.998
regulation of lymphocyte differentiationGO:00456191070.998
positive regulation of t cell differentiationGO:0045582520.997
t cell proliferationGO:00420981200.997
negative regulation of leukocyte differentiationGO:1902106510.997
positive regulation of b cell proliferationGO:0030890240.997
erythrocyte differentiationGO:0030218880.996
extrinsic apoptotic signaling pathwayGO:00971911260.996
myeloid leukocyte activationGO:0002274830.996
cell fate commitmentGO:00451652100.996
somatic diversification of immune receptorsGO:0002200530.996
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.996
lymphocyte proliferationGO:00466511640.995
Mouse
regulation of erythrocyte differentiationGO:0045646230.995
positive regulation of regulatory t cell differentiationGO:004559140.994
positive regulation of cell developmentGO:00107202370.994
antigen receptor mediated signaling pathwayGO:0050851640.994
hematopoietic stem cell migrationGO:003570110.994
positive regulation of lymphocyte activationGO:00512511400.993
cytokine mediated signaling pathwayGO:00192211150.993
regulation of leukocyte differentiationGO:19021051590.993
positive regulation of translational initiationGO:004594840.992
negative regulation of myeloid leukocyte differentiationGO:0002762200.992
alpha beta t cell activationGO:0046631910.991
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.989
b cell receptor signaling pathwayGO:0050853200.989
positive t cell selectionGO:0043368230.989
regulation of hypersensitivityGO:0002883100.989
regulation of mast cell activationGO:0033003210.987
regulation of antigen receptor mediated signaling pathwayGO:0050854290.986
forebrain developmentGO:00309003020.986
myeloid cell differentiationGO:00300992330.986
cytokine biosynthetic processGO:0042089680.986
b cell proliferationGO:0042100530.984
Mouse
immune response regulating signaling pathwayGO:00027641250.984
regulation of cytokine biosynthetic processGO:0042035590.984
regulation of adaptive immune responseGO:0002819900.983
defense response to other organismGO:00985421970.983
cytosolic calcium ion homeostasisGO:0051480700.982
positive regulation of leukocyte differentiationGO:1902107860.981
regulation of toll like receptor 2 signaling pathwayGO:003413530.979
negative regulation of adaptive immune responseGO:0002820250.979
defense response to virusGO:0051607680.977
regulation of leukocyte proliferationGO:00706631210.975
Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.974
regulation of cd4 positive alpha beta t cell activationGO:2000514240.973
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.972
negative regulation of cell proliferationGO:00082852960.972
b cell mediated immunityGO:0019724710.971
dna metabolic processGO:00062593030.970
positive regulation of leukocyte proliferationGO:0070665730.970
negative regulation of apoptotic signaling pathwayGO:20012341040.968
adaptive immune responseGO:00022501550.968
immature b cell differentiationGO:0002327100.967
leukocyte proliferationGO:00706611720.967
Mouse
regulation of leukocyte mediated immunityGO:00027031040.966
columnar cuboidal epithelial cell differentiationGO:0002065820.966
myeloid leukocyte differentiationGO:00025731190.966
regulation of mast cell activation involved in immune responseGO:0033006170.965
gland developmentGO:00487323300.964
positive regulation of cytokine biosynthetic processGO:0042108400.964
positive regulation of isotype switching to igg isotypesGO:004830470.964
b cell activation involved in immune responseGO:0002312500.964
activation of immune responseGO:00022531380.961
regulation of corticotropin releasing hormone secretionGO:004339720.959
regulation of neuron differentiationGO:00456642810.959
homeostasis of number of cellsGO:00488722100.958
leukocyte mediated immunityGO:00024431740.957
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.957
myeloid cell activation involved in immune responseGO:0002275340.956
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.956
signal transduction in absence of ligandGO:0038034550.955
t cell receptor v d j recombinationGO:003315350.955
regulation of regulated secretory pathwayGO:1903305200.954
negative regulation of myeloid cell differentiationGO:0045638380.952
immunoglobulin mediated immune responseGO:0016064690.952
regulation of myeloid cell differentiationGO:0045637960.950
regulation of interleukin 6 productionGO:0032675550.950
regulation of toll like receptor 4 signaling pathwayGO:003414340.950
positive regulation of myeloid cell differentiationGO:0045639430.949
myeloid cell homeostasisGO:00022621140.948
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.948
positive regulation of cytokine productionGO:00018191740.946
positive regulation of tyrosine phosphorylation of stat proteinGO:0042531150.946
positive regulation of nervous system developmentGO:00519622210.946
regulation of toll like receptor signaling pathwayGO:0034121200.945
metal ion homeostasisGO:00550651890.945
regulated secretory pathwayGO:0045055320.943
negative regulation of growthGO:0045926990.943
apoptotic signaling pathwayGO:00971903060.942
leukocyte activation involved in immune responseGO:00023661260.940
positive regulation of adaptive immune responseGO:0002821610.939
cellular response to amino acid stimulusGO:0071230290.934
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.933
regulation of tolerance induction dependent upon immune responseGO:000265210.931
regulation of cell motilityGO:20001452360.931
i kappab kinase nf kappab signalingGO:0007249850.929
mast cell mediated immunityGO:0002448200.929
cellular response to dna damage stimulusGO:00069742070.927
amine metabolic processGO:0009308450.927
regulation of dendritic cell apoptotic processGO:200066830.924
lymphocyte homeostasisGO:0002260640.920
negative regulation of t cell mediated cytotoxicityGO:000191530.918
regulation of bindingGO:00510981110.918
dendritic cell differentiationGO:0097028260.916
thymic t cell selectionGO:0045061220.913
regulation of antimicrobial humoral responseGO:000275930.913
b cell homeostasisGO:0001782340.912
negative regulation of b cell activationGO:0050869270.909
regulation of inflammatory response to antigenic stimulusGO:0002861210.908
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.908
regulation of lymphocyte proliferationGO:00506701170.907
Mouse
divalent metal ion transportGO:00708381720.907
leukocyte homeostasisGO:0001776790.905
cellular amine metabolic processGO:0044106440.904
axonogenesisGO:00074092740.903
single organismal cell cell adhesionGO:00163371310.901
granulocyte differentiationGO:0030851170.901
neutrophil differentiationGO:003022330.900
mast cell activationGO:0045576270.900
immune response regulating cell surface receptor signaling pathwayGO:0002768800.899
positive regulation of chronic inflammatory response to antigenic stimulusGO:000287620.898
sequestering of metal ionGO:0051238190.898
positive regulation of cellular amine metabolic processGO:003324050.898
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.897
erk1 and erk2 cascadeGO:0070371770.896
regulation of apoptotic signaling pathwayGO:20012331970.893
regulation of cellular amino acid metabolic processGO:000652150.893
toll like receptor 4 signaling pathwayGO:003414290.892
fc receptor mediated inhibitory signaling pathwayGO:000277410.891
negative regulation of homeostatic processGO:0032845710.890
regulation of cytokine productionGO:00018172660.889
regulation of b cell proliferationGO:0030888390.889
Mouse
natural killer cell differentiationGO:0001779210.889
lymph node developmentGO:0048535180.888
neuron projection guidanceGO:00974851410.887
mast cell activation involved in immune responseGO:0002279200.887
positive regulation of chronic inflammatory responseGO:000267840.885
axon guidanceGO:00074111410.882
regulation of t cell activationGO:00508631700.881
muscle fiber developmentGO:0048747760.878
regulation of lymphocyte activationGO:00512492400.877
tumor necrosis factor biosynthetic processGO:0042533100.877
regulation of alpha beta t cell differentiationGO:0046637350.877
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.871
immunoglobulin secretionGO:0048305170.862
regulation of neutrophil differentiationGO:004565820.862
positive regulation of tyrosine phosphorylation of stat5 proteinGO:004252360.860
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.860
regulation of t cell receptor signaling pathwayGO:0050856210.859
cellular response to molecule of bacterial originGO:0071219830.856
negative regulation of immune system processGO:00026832090.855
epithelial tube morphogenesisGO:00605623030.855
somatic diversification of immunoglobulinsGO:0016445430.855
negative regulation of t cell mediated immunityGO:000271090.853
immune response inhibiting signal transductionGO:000276540.852
positive regulation of translational initiation by ironGO:004599420.852
regulation of epithelial cell proliferationGO:00506781410.844
negative regulation of protein serine threonine kinase activityGO:0071901490.842
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.830
cellular response to cytokine stimulusGO:00713451890.828
regulation of leukocyte apoptotic processGO:2000106560.826
positive regulation of antigen receptor mediated signaling pathwayGO:005085790.823
regulation of cellular amine metabolic processGO:0033238200.821
immunoglobulin v d j recombinationGO:003315250.821
positive regulation of b cell activationGO:0050871490.820
negative regulation of protein modification processGO:00314001630.820
positive regulation of jnk cascadeGO:0046330460.819
telencephalon developmentGO:00215371860.819
maintenance of locationGO:0051235890.816
branching morphogenesis of an epithelial tubeGO:00487541590.816
myd88 independent toll like receptor signaling pathwayGO:000275630.815
hematopoietic progenitor cell differentiationGO:00022441430.811
inflammatory response to antigenic stimulusGO:0002437300.807
myeloid leukocyte mediated immunityGO:0002444420.805
thymus developmentGO:0048538410.798
positive regulation of exocytosisGO:0045921200.793
regulation of sequence specific dna binding transcription factor activityGO:00510901060.790
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.789
somatic recombination of immunoglobulin gene segmentsGO:0016447420.783
negative regulation of cellular amine metabolic processGO:003323910.777
osteoclast differentiationGO:0030316620.772
regulation of tumor necrosis factor productionGO:0032680490.770
somatic recombination of t cell receptor gene segmentsGO:000268150.767
single organism cell adhesionGO:00986021560.763
regulation of tyrosine phosphorylation of stat5 proteinGO:004252280.763
innate immune response activating signal transductionGO:0002758500.762
tolerance induction to self antigenGO:000251340.761
negative regulation of molecular functionGO:00440922580.756
motor neuron axon guidanceGO:0008045260.753
calcium ion transport into cytosolGO:0060402480.750
integrin mediated signaling pathwayGO:0007229270.750
positive regulation of growthGO:00459271040.750
regulation of cellular ketone metabolic processGO:0010565660.746
epithelial cell proliferationGO:00506731740.745
positive regulation of myeloid leukocyte differentiationGO:0002763260.745
tissue remodelingGO:00487711020.742
membrane organizationGO:00610242450.741
lymphocyte mediated immunityGO:00024491390.736
regulation of mast cell degranulationGO:0043304160.735
morphogenesis of a branching epitheliumGO:00611381930.734
positive regulation of b cell receptor signaling pathwayGO:005086140.732
cd4 positive alpha beta t cell differentiationGO:0043367410.732
defense response to bacteriumGO:00427421190.731
regulation of t cell differentiationGO:0045580830.728
regulation of translational initiationGO:0006446150.723
release of sequestered calcium ion into cytosolGO:0051209420.723
isotype switchingGO:0045190360.722
response to organic cyclic compoundGO:00140701980.722
cellular metal ion homeostasisGO:00068751510.721
phospholipid metabolic processGO:0006644870.716
regulation of tumor necrosis factor biosynthetic processGO:0042534100.716
regulation of kinase activityGO:00435492490.715
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.714
histamine production involved in inflammatory responseGO:000234910.712
cytokine productionGO:00018163190.709
extracellular matrix organizationGO:00301981470.704
muscle cell developmentGO:00550011330.704
covalent chromatin modificationGO:00165691630.701
t cell lineage commitmentGO:0002360130.701
mammary gland epithelial cell proliferationGO:0033598240.698
negative regulation of protein metabolic processGO:00512482820.698
tyrosine phosphorylation of stat proteinGO:0007260230.692
interleukin 12 productionGO:0032615320.690
regulation of cell cycleGO:00517262810.689
regionalizationGO:00030023370.689
regulation of t cell costimulationGO:200052320.689
interleukin 6 productionGO:0032635580.687
positive regulation of podosome assemblyGO:007180330.685
activation of cysteine type endopeptidase activityGO:0097202270.685
eosinophil degranulationGO:004330810.684
bmp signaling pathwayGO:0030509930.683
regulation of exocytosisGO:0017157610.681
negative regulation of toll like receptor signaling pathwayGO:0034122140.680
prostaglandin transportGO:001573270.679
sensory organ morphogenesisGO:00905962420.679
regulation of skeletal muscle fiber developmentGO:0048742360.677
osteoclast proliferationGO:000215840.677
positive regulation of lymphocyte differentiationGO:0045621610.674
regulation of b cell receptor signaling pathwayGO:005085590.671
extracellular structure organizationGO:00430621480.671
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.669
inflammatory responseGO:00069542440.665
cytoplasmic transportGO:00164822340.660
oligodendrocyte developmentGO:0014003200.660
odontogenesisGO:0042476780.659
regulation of granulocyte differentiationGO:003085280.658
positive regulation of hematopoietic stem cell migrationGO:200047310.657
regulation of map kinase activityGO:00434051200.656
humoral immune responseGO:0006959570.653
regulation of multi organism processGO:00439001110.652
cellular amino acid metabolic processGO:00065201030.646
regulation of t helper 1 type immune responseGO:0002825170.645
positive regulation of neuron differentiationGO:00456661410.645
peptidyl amino acid modificationGO:00181933360.643
histone modificationGO:00165701590.641
regulation of humoral immune responseGO:0002920220.639
positive regulation of leukocyte apoptotic processGO:2000108210.636
olfactory bulb axon guidanceGO:007167810.635
interferon gamma productionGO:0032609670.634
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.634
regulation of jak stat cascadeGO:0046425340.632
regulation of monocyte extravasationGO:200043720.629
response to ethanolGO:0045471180.629
dephosphorylationGO:00163111290.628
regulation of immunoglobulin mediated immune responseGO:0002889370.626
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.626
stem cell proliferationGO:00720891170.625
cellular ion homeostasisGO:00068731650.622
positive regulation of monocyte extravasationGO:200043910.618
somatic diversification of t cell receptor genesGO:000256850.617
posttranscriptional regulation of gene expressionGO:00106081550.617
production of molecular mediator of immune responseGO:00024401030.616
positive regulation of antibacterial peptide biosynthetic processGO:000696310.611
skin developmentGO:00435882200.608
anatomical structure homeostasisGO:00602491450.608
platelet aggregationGO:0070527200.607
regulation of protein stabilityGO:0031647520.607
positive regulation of cell migrationGO:00303351090.602
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.601
mammary gland epithelium developmentGO:0061180650.600
t helper cell differentiationGO:0042093280.600
striated muscle cell developmentGO:00550021250.599
megakaryocyte differentiationGO:0030219260.598
stem cell maintenanceGO:00198271300.591
negative regulation of immune effector processGO:0002698550.589
morphogenesis of a branching structureGO:00017632030.588
response to organonitrogen compoundGO:00102432460.584
detection of mechanical stimulus involved in sensory perception of painGO:005096640.583
exocrine system developmentGO:0035272450.582
positive regulation of mapk cascadeGO:00434101700.581
regulation of stress activated mapk cascadeGO:0032872690.581
positive regulation of erythrocyte differentiationGO:0045648110.579
cellular chemical homeostasisGO:00550822150.577
positive regulation of lymphocyte proliferationGO:0050671700.577
muscle cell differentiationGO:00426922610.577
positive regulation of cytosolic calcium ion concentrationGO:0007204650.574
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.572
response to lipopolysaccharideGO:00324961280.568
transmission of nerve impulseGO:0019226760.566
regulation of striated muscle cell differentiationGO:0051153810.564
regulation of organelle organizationGO:00330432890.563
positive regulation of alpha beta t cell differentiationGO:0046638280.562
positive regulation of stress activated mapk cascadeGO:0032874480.560
sphingolipid metabolic processGO:0006665450.560
metanephros developmentGO:0001656790.553
stem cell developmentGO:00488642190.551
positive regulation of protein modification processGO:00314012990.549
cd4 positive alpha beta t cell activationGO:0035710450.549
multicellular organismal homeostasisGO:00488711640.548
eosinophil activationGO:004330710.545
regulation of jun kinase activityGO:0043506400.545
regulation of podosome assemblyGO:007180130.540
myeloid dendritic cell differentiationGO:0043011160.539
cytosolic calcium ion transportGO:0060401480.538
angiogenesisGO:00015252010.538
negative regulation of map kinase activityGO:0043407340.536
actin cytoskeleton organizationGO:00300362200.534
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.531
regulation of ion transportGO:00432692150.528
germ cell developmentGO:00072811850.527
lymphocyte activation involved in immune responseGO:0002285930.526
dendritic cell apoptotic processGO:009704830.519
negative regulation of osteoblast differentiationGO:0045668300.518
calcium ion homeostasisGO:00550741270.516
protein localization to nucleusGO:00345041210.514
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.511
regulation of interleukin 2 productionGO:0032663280.510
negative regulation of t helper 1 cell differentiationGO:004562630.510
gonad developmentGO:00084061410.510
intrinsic apoptotic signaling pathwayGO:00971931320.507
regulation of vasculature developmentGO:1901342880.506
calcium ion transportGO:00068161590.505
regulation of chemotaxisGO:0050920530.503
negative regulation of cellular amino acid metabolic processGO:004576300.502
regulation of alpha beta t cell activationGO:0046634530.502
phagocytosisGO:0006909660.502
t cell differentiation involved in immune responseGO:0002292300.497
positive regulation of apoptotic signaling pathwayGO:2001235950.495
cell fate determinationGO:0001709320.493
negative regulation of interleukin 5 productionGO:003271440.493
observational learningGO:009859710.491
positive regulation of interleukin 6 productionGO:0032755370.489
regulation of release of cytochrome c from mitochondriaGO:0090199110.487
skeletal muscle fiber developmentGO:0048741580.485
striated muscle tissue developmentGO:00147062930.483
b cell lineage commitmentGO:000232640.482
positive regulation of myoblast differentiationGO:004566380.482
humoral immune response mediated by circulating immunoglobulinGO:0002455140.480
regulation of translational initiation by ironGO:000644720.479
chemotaxisGO:00069352470.479
central nervous system neuron differentiationGO:00219531620.478
regulation of ion homeostasisGO:2000021640.477
positive regulation of organelle organizationGO:00106381280.475
regulation of cellular component sizeGO:00325351210.475
granulocyte activationGO:0036230100.474
positive regulation of hypersensitivityGO:000288570.470
positive regulation of secretion by cellGO:19035321140.469
regulation of defense response to virus by hostGO:005069180.469
regulation of b cell apoptotic processGO:0002902130.466
regulation of chronic inflammatory responseGO:000267670.461
positive regulation of t cell mediated immunityGO:0002711240.459
regulation of calcium ion transport into cytosolGO:0010522310.459
positive regulation of osteoclast differentiationGO:0045672150.457
regulation of secretionGO:00510462740.454
bone resorptionGO:0045453380.454
carbohydrate derivative biosynthetic processGO:19011371830.449
regulation of lymphocyte mediated immunityGO:0002706840.447
positive regulation of mast cell degranulationGO:0043306100.446
mitochondrial outer membrane permeabilization involved in programmed cell deathGO:1902686110.446
positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292560.445
negative regulation of toll like receptor 2 signaling pathwayGO:003413630.443
positive regulation of interleukin 12 productionGO:0032735210.440
compound eye developmentGO:004874910.439
zymogen activationGO:0031638410.439
endodermal cell fate specificationGO:000171440.437
positive regulation of lymphocyte mediated immunityGO:0002708620.435
osteoclast developmentGO:003603590.434
positive regulation of map kinase activityGO:0043406840.433
fc receptor mediated stimulatory signaling pathwayGO:000243140.431
gliogenesisGO:00420631410.428
learned vocalization behavior or vocal learningGO:009859810.428
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.426
hypermethylation of cpg islandGO:004402730.425
regulation of regulatory t cell differentiationGO:004558970.425
muscle tissue developmentGO:00605373080.424
cytokine production involved in immune responseGO:0002367340.420
positive regulation of osteoclast developmentGO:200120630.418
stem cell differentiationGO:00488632680.418
myotube differentiationGO:00149021050.417
chromatin organizationGO:00063252060.417
regulation of protein localizationGO:00328802310.416
tumor necrosis factor superfamily cytokine productionGO:0071706510.416
glycoprotein metabolic processGO:00091001160.415
hair follicle developmentGO:0001942850.415
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.414
response to ionizing radiationGO:0010212420.414
positive regulation of interferon gamma productionGO:0032729390.412
carboxylic acid transportGO:00469421000.412
response to platelet derived growth factorGO:003611960.412
protection from non homologous end joining at telomereGO:003184840.407
regulation of myeloid leukocyte mediated immunityGO:0002886250.404
lymphoid progenitor cell differentiationGO:0002320170.403
divalent inorganic cation transportGO:00725111780.401
leukocyte apoptotic processGO:0071887710.400
cell maturationGO:00484691270.399
platelet degranulationGO:000257660.399
translational initiationGO:0006413240.398
alpha beta t cell differentiation involved in immune responseGO:0002293300.398
mast cell proliferationGO:007066240.397
regulation of leukocyte degranulationGO:0043300200.396
alpha beta t cell proliferationGO:0046633210.396
myeloid leukocyte migrationGO:0097529570.396
digestive tract developmentGO:00485651900.396
positive regulation of cysteine type endopeptidase activityGO:2001056390.394
lysosome localizationGO:0032418200.392
negative regulation of mast cell proliferationGO:007066710.392
regulation of cell migrationGO:00303342190.391
male gamete generationGO:00482322850.390
positive regulation of innate immune responseGO:0045089800.388
positive regulation of oligodendrocyte differentiationGO:004871490.388
response to dsrnaGO:0043331300.387
chromatin modificationGO:00165681870.387
oligodendrocyte differentiationGO:0048709530.386
positive regulation of myeloid leukocyte mediated immunityGO:0002888140.385
regulation of oligodendrocyte differentiationGO:0048713230.385
salivary gland morphogenesisGO:0007435330.384
tissue homeostasisGO:00018941150.383
positive regulation of release of cytochrome c from mitochondriaGO:009020050.382
regulation of hydrolase activityGO:00513362460.379
positive regulation of phospholipase c activityGO:001086320.378
developmental maturationGO:00217001930.374
nk t cell differentiationGO:000186580.373
isotype switching to igg isotypesGO:0048291100.373
apical constrictionGO:000338340.372
regulation of mast cell proliferationGO:007066640.372
positive regulation of gliogenesisGO:0014015270.371
positive regulation of cellular amino acid metabolic processGO:004576430.370
negative regulation of b cell mediated immunityGO:000271370.370
regulation of cysteine type endopeptidase activityGO:2000116650.369
positive regulation of leukocyte mediated immunityGO:0002705700.369
neuroblast fate determinationGO:000740010.368
regulation of b cell mediated immunityGO:0002712370.368
negative regulation of t cell activationGO:0050868650.367
negative regulation of cell activationGO:00508661110.366
branching involved in mammary gland duct morphogenesisGO:0060444270.365
response to molecule of bacterial originGO:00022371430.363
regulation of anatomical structure sizeGO:00900661780.363
negative regulation of cell developmentGO:00107211690.363
tolerance inductionGO:0002507140.361
gamma delta t cell differentiationGO:0042492110.361
positive regulation of neuron projection developmentGO:0010976790.359
regulation of protein serine threonine kinase activityGO:00719001570.358
b cell apoptotic processGO:0001783190.358
regulation of cell divisionGO:0051302760.356
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.356

Ikzf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.911
disease of anatomical entityDOID:700.911
myeloid leukemiaDOID:869200.728
immune system cancerDOID:006008300.728
hematologic cancerDOID:253100.728
cancerDOID:16200.728
leukemiaDOID:124000.728
disease of cellular proliferationDOID:1456600.728
organ system cancerDOID:005068600.728
disease by infectious agentDOID:005011700.609
viral infectious diseaseDOID:93400.609
primary immunodeficiency diseaseDOID:61200.604
blood protein diseaseDOID:62000.580
agammaglobulinemiaDOID:258300.580
common variable immunodeficiencyDOID:1217700.580
b cell deficiencyDOID:211500.580
hematopoietic system diseaseDOID:7400.580
human immunodeficiency virus infectious diseaseDOID:52600.566
severe combined immunodeficiencyDOID:62700.436
combined t cell and b cell immunodeficiencyDOID:62800.436