Mus musculus

16 known processes

Phc1

polyhomeotic-like 1 (Drosophila)

(Aliases: Rae-28,rae28,Edr1,AW557034,Edr,Mph1)

Phc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of immature t cell proliferationGO:003309140.987
cell cycle comprising mitosis without cytokinesisGO:003330110.956
Fly
gene silencingGO:0016458380.622
Fly
chromatin modificationGO:00165681870.616
Human
dna metabolic processGO:00062593030.483
axonogenesisGO:00074092740.435
skeletal system morphogenesisGO:00487052030.394
dna alkylationGO:0006305430.383
spermatogenesisGO:00072832840.325
Mouse
cilium morphogenesisGO:00602711020.316
cilium assemblyGO:0042384810.284
embryonic skeletal system developmentGO:00487061200.278
regionalizationGO:00030023370.277
b cell activationGO:00421131610.241
chromatin organizationGO:00063252060.239
Human
cellular response to dna damage stimulusGO:00069742070.234
regulation of interleukin 6 productionGO:0032675550.215
neural tube developmentGO:00219151600.210
digestive tract morphogenesisGO:00485461470.190
dna methylationGO:0006306430.179
cellular response to acid chemicalGO:0071229680.168
cellular response to lipidGO:00713961450.163
histone acetylationGO:0016573410.159
tube formationGO:00351481400.149
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.145
spinal cord developmentGO:0021510810.136
male gamete generationGO:00482322850.130
Mouse
response to acid chemicalGO:00011011110.129
cytokine productionGO:00018163190.126
internal protein amino acid acetylationGO:0006475420.124
negative regulation of tor signalingGO:0032007130.116
response to retinoic acidGO:0032526560.113
peptidyl amino acid modificationGO:00181933360.109
protein modification by small protein conjugation or removalGO:00706472070.105
Human
small gtpase mediated signal transductionGO:0007264970.105
embryonic organ morphogenesisGO:00485622760.103
peptidyl lysine acetylationGO:0018394450.101
neural tube closureGO:0001843900.099
covalent chromatin modificationGO:00165691630.099
Human
tumor necrosis factor superfamily cytokine productionGO:0071706510.095
regulation of lymphocyte differentiationGO:00456191070.095
neuron projection guidanceGO:00974851410.094
skeletal system developmentGO:00015013560.093
regulation of b cell proliferationGO:0030888390.090
positive regulation of immature t cell proliferation in thymusGO:003309230.086
positive regulation of t cell activationGO:00508701010.085
dna modificationGO:0006304500.085
chromatin remodelingGO:0006338320.085
central nervous system neuron differentiationGO:00219531620.083
Fly
response to oxidative stressGO:00069791230.081
mitotic cell cycleGO:00002781950.076
Fly
ribose phosphate metabolic processGO:00196932910.073
ras protein signal transductionGO:0007265770.072
regulation of anatomical structure sizeGO:00900661780.068
positive regulation of lymphocyte activationGO:00512511400.068
protein ubiquitinationGO:00165671710.066
Human
positive regulation of leukocyte differentiationGO:1902107860.065
gastrulationGO:00073691160.064
regulation of cytokine productionGO:00018172660.063
cytoplasmic transportGO:00164822340.063
neural tube formationGO:00018411080.063
t cell activationGO:00421102890.063
positive regulation of t cell proliferationGO:0042102520.062
ribonucleotide metabolic processGO:00092592910.060
ear developmentGO:00435832000.060
regulation of t cell activationGO:00508631700.059
macromolecule methylationGO:00434141200.059
dna repairGO:00062811070.059
apoptotic signaling pathwayGO:00971903060.058
gland developmentGO:00487323300.058
lymphocyte proliferationGO:00466511640.058
central nervous system neuron developmentGO:0021954670.057
Fly
mitotic cell cycle embryonicGO:004544850.056
Fly
tumor necrosis factor productionGO:0032640500.056
methylationGO:00322591340.054
3 utr mediated mrna stabilizationGO:007093520.053
digestive tract developmentGO:00485651900.052
production of molecular mediator of immune responseGO:00024401030.052
response to reactive oxygen speciesGO:0000302560.052
regulation of transcription from rna polymerase iii promoterGO:000635920.051
regulation of cell activationGO:00508652890.051
positive regulation of lymphocyte differentiationGO:0045621610.050
histone methylationGO:0016571710.050
regulation of lymphocyte activationGO:00512492400.049
response to alcoholGO:0097305480.049
Fly
regulation of t cell differentiationGO:0045580830.048
myeloid cell differentiationGO:00300992330.048
negative regulation of protein metabolic processGO:00512482820.048
regulation of tumor necrosis factor productionGO:0032680490.047
toll like receptor signaling pathwayGO:0002224380.047
leukocyte proliferationGO:00706611720.047
protein acylationGO:0043543640.046
regulation of immature t cell proliferation in thymusGO:003308460.046
embryonic skeletal system morphogenesisGO:0048704910.046
posttranscriptional regulation of gene expressionGO:00106081550.046
sensory perception of soundGO:0007605970.046
histone deubiquitinationGO:001657820.045
positive regulation of b cell activationGO:0050871490.045
protein targetingGO:00066051430.045
homeostasis of number of cellsGO:00488722100.045
embryonic epithelial tube formationGO:00018381300.044
camera type eye developmentGO:00430102660.044
positive regulation of cell activationGO:00508671580.044
regulation of b cell activationGO:0050864810.043
regulation of defense responseGO:00313472330.043
cellular amino acid metabolic processGO:00065201030.043
response to organonitrogen compoundGO:00102432460.042
antimicrobial peptide productionGO:000277520.041
protein modification by small protein conjugationGO:00324461870.040
Human
peptidyl serine phosphorylationGO:0018105740.040
regulation of leukocyte differentiationGO:19021051590.040
gastrulation with mouth forming secondGO:0001702290.040
cell agingGO:0007569350.039
regulation of neuron projection developmentGO:00109751690.038
positive regulation of organelle organizationGO:00106381280.038
regulation of cell motilityGO:20001452360.038
regulation of cellular catabolic processGO:00313292420.037
epithelial cell proliferationGO:00506731740.037
negative regulation of intracellular signal transductionGO:19025321670.035
p38mapk cascadeGO:003806640.035
vascular endothelial growth factor receptor signaling pathwayGO:0048010240.035
cellular protein catabolic processGO:00442571550.034
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.034
stress induced premature senescenceGO:009040020.033
primary neural tube formationGO:0014020950.033
histone modificationGO:00165701590.033
Human
immune effector processGO:00022523210.032
chemotaxisGO:00069352470.032
cellular response to retinoic acidGO:0071300250.032
morphogenesis of an epithelial sheetGO:0002011270.031
nucleoside phosphate metabolic processGO:00067533380.031
purine ribonucleotide metabolic processGO:00091502900.031
hindbrain developmentGO:00309021280.031
tor signalingGO:0031929210.031
positive regulation of nervous system developmentGO:00519622210.031
tube closureGO:0060606910.031
regulation of neuron differentiationGO:00456642810.031
peptidyl lysine modificationGO:0018205770.031
protein catabolic processGO:00301632210.031
stress activated protein kinase signaling cascadeGO:0031098810.030
response to ketoneGO:1901654150.030
Fly
angiogenesisGO:00015252010.030
macropinocytosisGO:004435140.030
regulation of jnk cascadeGO:0046328620.029
regulation of t cell proliferationGO:0042129920.029
positive regulation of defense responseGO:00313491240.028
negative regulation of cellular protein metabolic processGO:00322692470.028
regulation of cellular component sizeGO:00325351210.028
stem cell differentiationGO:00488632680.028
regulation of transcription during meiosisGO:005103710.028
innate immune responseGO:00450871570.028
blastocyst developmentGO:0001824800.028
endocytosisGO:00068971680.028
protein methylationGO:0006479810.027
response to growth factorGO:00708481980.027
regulation of homeostatic processGO:00328441820.027
negative regulation of cellular amino acid metabolic processGO:004576300.027
positive regulation of innate immune responseGO:0045089800.027
maintenance of locationGO:0051235890.027
negative regulation of phosphorylationGO:00423261660.026
renal system developmentGO:00720012250.026
protein autophosphorylationGO:0046777610.026
wnt signaling pathwayGO:00160551880.026
leukocyte differentiationGO:00025213420.026
response to hydrogen peroxideGO:0042542320.026
pattern recognition receptor signaling pathwayGO:0002221470.026
ossificationGO:00015032160.026
nucleoside phosphate catabolic processGO:19012922220.025
lymphocyte mediated immunityGO:00024491390.025
respiratory tube developmentGO:00303231670.025
cation homeostasisGO:00550802120.025
response to ionizing radiationGO:0010212420.025
epibolyGO:009050480.024
protein secretionGO:00093061110.024
t cell differentiationGO:00302171740.024
blood circulationGO:00080151950.024
regulation of antimicrobial peptide productionGO:000278410.024
positive regulation of t cell differentiation in thymusGO:0033089130.024
hematopoietic progenitor cell differentiationGO:00022441430.024
negative regulation of apoptotic signaling pathwayGO:20012341040.024
morphogenesis of embryonic epitheliumGO:00163311590.024
response to inorganic substanceGO:0010035960.024
cellular lipid metabolic processGO:00442553230.024
regulation of cellular ketone metabolic processGO:0010565660.024
second messenger mediated signalingGO:0019932730.023
sensory perception of mechanical stimulusGO:00509541070.023
regulation of antimicrobial humoral responseGO:000275930.023
histone h2a monoubiquitinationGO:003551810.023
cellular carbohydrate metabolic processGO:00442621190.023
epithelial tube formationGO:00721751300.023
trunk segmentationGO:003529040.023
single organism cell adhesionGO:00986021560.023
regulation of t cell differentiation in thymusGO:0033081240.023
neural tube patterningGO:0021532430.023
sensory perceptionGO:00076002450.023
cell cycle checkpointGO:0000075470.022
negative regulation of cellular amine metabolic processGO:003323910.022
positive regulation of cellular amine metabolic processGO:003324050.022
muscle cell differentiationGO:00426922610.022
organic cyclic compound catabolic processGO:19013612950.022
purine nucleotide metabolic processGO:00061633020.022
chromatin silencingGO:0006342150.022
regulation of defense response to bacteriumGO:190042430.022
intracellular receptor signaling pathwayGO:0030522740.021
maintenance of apical basal cell polarityGO:003509030.021
transcription from rna polymerase iii promoterGO:000638330.021
regulation of tor signalingGO:0032006170.021
amine metabolic processGO:0009308450.021
nucleobase containing small molecule metabolic processGO:00550863520.021
purine containing compound metabolic processGO:00725213110.021
meiosis iGO:0007127600.021
ubiquitin dependent protein catabolic processGO:00065111290.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.021
response to radiationGO:00093141650.021
immune response activating signal transductionGO:00027571160.020
macromolecule catabolic processGO:00090572810.020
regulation of protein transportGO:00512231630.020
blastocyst growthGO:0001832230.020
muscle tissue developmentGO:00605373080.020
cellular response to oxidative stressGO:0034599760.020
response to lipopolysaccharideGO:00324961280.020
lymphocyte differentiationGO:00300982420.020
regulation of myeloid leukocyte differentiationGO:0002761580.019
proteolysis involved in cellular protein catabolic processGO:00516031470.019
cellular response to organonitrogen compoundGO:00714171450.019
negative regulation of organelle organizationGO:0010639900.019
cellular response to vascular endothelial growth factor stimulusGO:0035924110.019
b cell proliferationGO:0042100530.019
protein importGO:00170381010.019
response to sterolGO:003631440.019
Fly
multicellular organismal signalingGO:0035637910.019
response to organic cyclic compoundGO:00140701980.019
Fly
negative regulation of cell proliferationGO:00082852960.019
demethylationGO:0070988230.019
dna dealkylationGO:0035510110.019
regulation of chromatin modificationGO:1903308570.019
gtp metabolic processGO:00460391440.019
ventral spinal cord developmentGO:0021517480.019
leukocyte mediated immunityGO:00024431740.019
positive regulation of protein modification processGO:00314012990.018
regulation of actin filament based processGO:0032970990.018
histone ubiquitinationGO:0016574100.018
Human
regulation of mrna stabilityGO:0043488230.018
internal peptidyl lysine acetylationGO:0018393420.018
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.018
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.018
calcium mediated signaling using intracellular calcium sourceGO:003558430.018
metal ion homeostasisGO:00550651890.018
cell fate commitmentGO:00451652100.018
regulation of leukocyte proliferationGO:00706631210.018
nuclear importGO:0051170950.018
aromatic compound catabolic processGO:00194392860.018
positive regulation of neuron differentiationGO:00456661410.018
transmission of nerve impulseGO:0019226760.018
positive regulation of protein phosphorylationGO:00019342420.018
positive regulation of cellular catabolic processGO:00313311480.017
immature t cell proliferationGO:003307980.017
regulation of synaptic growth at neuromuscular junctionGO:000858240.017
inorganic ion transmembrane transportGO:00986602340.017
response to molecule of bacterial originGO:00022371430.017
limb morphogenesisGO:00351081490.017
regulation of protein localizationGO:00328802310.017
protein localization to organelleGO:00333651850.017
protein localization to nucleusGO:00345041210.017
endodermal cell fate specificationGO:000171440.017
myeloid leukocyte differentiationGO:00025731190.017
spermatid developmentGO:00072861080.017
histone monoubiquitinationGO:001039030.017
carbohydrate metabolic processGO:00059752300.017
microtubule cytoskeleton organizationGO:00002261570.017
dna recombinationGO:0006310920.017
endocrine system developmentGO:0035270980.017
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.017
purine ribonucleoside metabolic processGO:00461282410.017
positive regulation of t cell differentiationGO:0045582520.017
protein deacylationGO:0035601360.016
respiratory system developmentGO:00605411900.016
lung developmentGO:00303241640.016
positive regulation of myeloid cell differentiationGO:0045639430.016
cellular amine metabolic processGO:0044106440.016
rho protein signal transductionGO:0007266320.016
signal transduction involved in mitotic dna damage checkpointGO:190240230.016
regulation of cell cycleGO:00517262810.016
positive regulation of hydrolase activityGO:00513451480.016
regulation of cell projection organizationGO:00313442060.016
pinocytosisGO:000690760.016
embryonic limb morphogenesisGO:00303261260.016
endomembrane system organizationGO:00102561470.016
response to insulinGO:00328681000.016
sequestering of metal ionGO:0051238190.016
rhythmic processGO:00485111740.016
regulation of cell shapeGO:0008360390.016
regulation of membrane potentialGO:00423911920.016
regulation of organ morphogenesisGO:20000271440.016
rab protein signal transductionGO:003248210.016
regulation of cell morphogenesis involved in differentiationGO:00107691510.016
regulation of protein stabilityGO:0031647520.016
proteasomal protein catabolic processGO:0010498980.016
lipid localizationGO:00108761260.016
regulation of myeloid cell differentiationGO:0045637960.016
development of primary sexual characteristicsGO:00451371430.015
regulation of apoptotic signaling pathwayGO:20012331970.015
calcium mediated signalingGO:0019722460.015
inflammatory responseGO:00069542440.015
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.015
positive regulation of cell projection organizationGO:0031346950.015
lymphocyte activation involved in immune responseGO:0002285930.015
regulation of cellular amino acid metabolic processGO:000652150.015
regulation of cellular response to stressGO:00801351590.015
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.015
histone h4 k16 acetylationGO:004398430.015
organelle fissionGO:00482851700.015
urogenital system developmentGO:00016552610.015
regulation of cellular component biogenesisGO:00440871810.015
circulatory system processGO:00030131970.015
regulation of hormone levelsGO:00108172110.015
epithelial tube morphogenesisGO:00605623030.014
cell adhesionGO:00071553290.014
circadian rhythmGO:00076231140.014
positive regulation of nucleotide metabolic processGO:00459811140.014
somitogenesisGO:0001756690.014
ribonucleoside triphosphate metabolic processGO:00091992200.014
cellular response to insulin stimulusGO:0032869780.014
negative regulation of immune system processGO:00026832090.014
regulation of striated muscle cell differentiationGO:0051153810.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
regulation of antimicrobial peptide biosynthetic processGO:000280510.014
cerebellum developmentGO:0021549770.014
forebrain developmentGO:00309003020.014
regulation of nucleoside metabolic processGO:00091181300.014
dna demethylationGO:0080111100.014
biomineral tissue developmentGO:0031214640.014
adaptive immune responseGO:00022501550.014
glycosyl compound catabolic processGO:19016582060.014
regulation of cytoskeleton organizationGO:00514931220.014
regulation of myotube differentiationGO:0010830620.013
purine nucleoside catabolic processGO:00061522050.013
fat cell differentiationGO:00454441600.013
regulation of nucleotide catabolic processGO:00308111220.013
multicellular organism growthGO:00352641610.013
negative regulation of gene expression epigeneticGO:0045814150.013
kidney developmentGO:00018222130.013
oocyte constructionGO:000730820.013
regulation of ion transmembrane transportGO:00347651190.013
chondrocyte hypertrophyGO:000341540.013
myeloid cell homeostasisGO:00022621140.013
tissue remodelingGO:00487711020.013
regulation of hydrolase activityGO:00513362460.013
cartilage developmentGO:00512161400.013
regulation of cell migrationGO:00303342190.013
macromolecule deacylationGO:0098732370.013
humoral immune responseGO:0006959570.013
meiotic cell cycleGO:00513211220.013
cardiac muscle cell contractionGO:008600370.012
spermatid differentiationGO:00485151150.012
innate immune response activating signal transductionGO:0002758500.012
regulation of cilium assemblyGO:190201770.012
regulation of secretion by cellGO:19035302490.012
response to light stimulusGO:00094161350.012
bmp signaling pathwayGO:0030509930.012
heterochromatin organizationGO:007082840.012
habituationGO:004695930.012
regulation of multi organism processGO:00439001110.012
regulation of purine nucleotide metabolic processGO:19005421690.012
negative regulation of lymphocyte activationGO:0051250910.012
regulation of nucleocytoplasmic transportGO:0046822730.012
segmentationGO:0035282930.012
limb developmentGO:00601731660.012
blood vessel morphogenesisGO:00485142850.012
retina development in camera type eyeGO:00600411190.012
regulation of organelle organizationGO:00330432890.012
single fertilizationGO:0007338820.012
establishment of planar polarityGO:0001736280.012
negative regulation of defense responseGO:0031348770.012
regulation of secretionGO:00510462740.012
regulation of nucleotide metabolic processGO:00061401690.012
proprioceptionGO:001923040.012
intraciliary retrograde transportGO:003572130.012
smoothened signaling pathwayGO:00072241050.012
glycosyl compound metabolic processGO:19016572460.012
regulation of chromosome organizationGO:0033044830.012
oocyte anterior posterior axis specificationGO:000731420.012
oocyte axis specificationGO:000730920.012
potassium ion homeostasisGO:005507540.012
leukocyte activation involved in immune responseGO:00023661260.012
cellular nitrogen compound catabolic processGO:00442702800.012
heterocycle catabolic processGO:00467002800.012
regulation of chromatin silencingGO:003193520.012
calcium ion transportGO:00068161590.012
cardiac chamber morphogenesisGO:0003206930.012
regulation of smoothened signaling pathwayGO:0008589580.012
negative regulation of protein modification processGO:00314001630.012
negative regulation of chromatin silencingGO:003193610.012
immunoglobulin mediated immune responseGO:0016064690.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
cell activation involved in immune responseGO:00022631260.011
regulation of mitotic cell cycle phase transitionGO:1901990730.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
regulation of production of molecular mediator of immune responseGO:0002700650.011
regulation of bindingGO:00510981110.011
regulation of neural precursor cell proliferationGO:2000177700.011
nucleotide catabolic processGO:00091662170.011
sequestering of calcium ionGO:0051208180.011
negative regulation of dna replicationGO:000815640.011
metencephalon developmentGO:0022037890.011
forebrain neuron fate commitmentGO:0021877130.011
action potentialGO:0001508780.011
positive regulation of gtp catabolic processGO:0033126850.011
positive regulation of cell growthGO:0030307330.011
phospholipid metabolic processGO:0006644870.011
cardiocyte differentiationGO:0035051870.011
regulation of inflammatory responseGO:00507271470.011
regulation of transferase activityGO:00513382630.011
digestive system developmentGO:00551232000.011
positive regulation of protein catabolic processGO:0045732600.011
actin mediated cell contractionGO:0070252150.011
regulation of ras protein signal transductionGO:00465781140.011
organophosphate biosynthetic processGO:00904071220.011
cell growthGO:00160491300.011
morphogenesis of a polarized epitheliumGO:0001738370.011
bone mineralizationGO:0030282540.011
regulation of protein targetingGO:1903533610.011
positive regulation of cytokine productionGO:00018191740.011
neuronal action potentialGO:0019228540.011
antimicrobial peptide biosynthetic processGO:000277720.011
developmental maturationGO:00217001930.011
activation of immune responseGO:00022531380.011
organophosphate catabolic processGO:00464342320.011
cellular ion homeostasisGO:00068731650.011
regulation of stem cell proliferationGO:0072091780.011
regulation of innate immune responseGO:0045088910.011
b cell differentiationGO:0030183780.011
positive regulation of dna templated transcription elongationGO:003278620.011
regulation of mitotic cell cycleGO:00073461260.011
negative regulation of synapse assemblyGO:005196430.011
immune response regulating signaling pathwayGO:00027641250.011
calcium ion homeostasisGO:00550741270.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
reactive nitrogen species metabolic processGO:200105700.011
cellular macromolecule catabolic processGO:00442652060.010
positive regulation of cell cycleGO:0045787920.010
nuclear transportGO:00511691390.010
connective tissue developmentGO:00614481790.010
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.010
isotype switchingGO:0045190360.010
cell divisionGO:00513011200.010
protein deubiquitinationGO:0016579190.010
cellular response to organic cyclic compoundGO:0071407870.010
protein maturationGO:00516041760.010
regulation of cellular protein catabolic processGO:1903362610.010
inner ear morphogenesisGO:00424721010.010
somatic diversification of immune receptorsGO:0002200530.010
localization within membraneGO:005166840.010
regulation of rna stabilityGO:0043487260.010
regulation of immature t cell proliferationGO:003308370.010
epithelial cell developmentGO:00020641590.010
Fly
midbrain hindbrain boundary morphogenesisGO:002155540.010
negative regulation of protein maturationGO:1903318790.010
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.010
regulation of lymphocyte mediated immunityGO:0002706840.010
germ cell developmentGO:00072811850.010
Fly
developmental growth involved in morphogenesisGO:00605601380.010

Phc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.011
disease of anatomical entityDOID:700.011
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010