Mus musculus

0 known processes

Sh2d4b

SH2 domain containing 4B

(Aliases: D030001E08,A430109M18Rik)

Sh2d4b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
g protein coupled receptor signaling pathwayGO:00071862430.069
cytokine productionGO:00018163190.067
transmembrane transportGO:00550854120.058
membrane organizationGO:00610242450.057
amine metabolic processGO:0009308450.054
leukocyte differentiationGO:00025213420.051
regulation of membrane potentialGO:00423911920.050
Mouse
cellular amino acid metabolic processGO:00065201030.049
cellular amine metabolic processGO:0044106440.044
regulation of cytokine productionGO:00018172660.043
regulation of cellular amine metabolic processGO:0033238200.043
small gtpase mediated signal transductionGO:0007264970.041
ras protein signal transductionGO:0007265770.041
regulation of lymphocyte activationGO:00512492400.041
cellular metal ion homeostasisGO:00068751510.039
male gamete generationGO:00482322850.038
ion transmembrane transportGO:00342203610.037
regulation of defense responseGO:00313472330.037
inflammatory responseGO:00069542440.036
maintenance of locationGO:0051235890.036
cellular ketone metabolic processGO:0042180840.036
dna metabolic processGO:00062593030.036
response to molecule of bacterial originGO:00022371430.035
spermatogenesisGO:00072832840.034
cell type specific apoptotic processGO:00972852680.034
Mouse
regulation of mapk cascadeGO:00434082480.033
cellular homeostasisGO:00197252400.033
regulation of cell cycleGO:00517262810.033
regulation of protein localizationGO:00328802310.033
cation transmembrane transportGO:00986552660.032
positive regulation of programmed cell deathGO:00430682180.032
synaptic transmissionGO:00072683290.031
regulation of cellular amino acid metabolic processGO:000652150.031
nucleobase containing small molecule metabolic processGO:00550863520.030
macromolecule catabolic processGO:00090572810.030
organonitrogen compound biosynthetic processGO:19015661920.030
t cell activationGO:00421102890.029
Mouse
regulation of neuron differentiationGO:00456642810.029
positive regulation of cellular amine metabolic processGO:003324050.029
purine containing compound metabolic processGO:00725213110.029
response to organonitrogen compoundGO:00102432460.029
regulation of leukocyte differentiationGO:19021051590.029
regulation of cell motilityGO:20001452360.029
protein catabolic processGO:00301632210.029
defense response to bacteriumGO:00427421190.029
action potentialGO:0001508780.029
cation homeostasisGO:00550802120.029
apoptotic signaling pathwayGO:00971903060.028
sensory perceptionGO:00076002450.028
carbohydrate derivative biosynthetic processGO:19011371830.028
cellular chemical homeostasisGO:00550822150.028
forebrain developmentGO:00309003020.028
purine ribonucleotide metabolic processGO:00091502900.028
cation transportGO:00068123990.028
leukocyte migrationGO:00509001240.028
positive regulation of protein modification processGO:00314012990.027
inorganic ion transmembrane transportGO:00986602340.027
chemotaxisGO:00069352470.027
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.027
amino acid transportGO:0006865610.027
cellular ion homeostasisGO:00068731650.027
nitrogen compound transportGO:00717052710.026
regulation of response to woundingGO:19030341890.026
plasma membrane organizationGO:0007009900.026
anion transportGO:00068201770.026
skeletal system developmentGO:00015013560.026
nucleotide metabolic processGO:00091173320.026
carbohydrate metabolic processGO:00059752300.026
regulation of cellular ketone metabolic processGO:0010565660.025
cytoplasmic transportGO:00164822340.025
regionalizationGO:00030023370.025
endomembrane system organizationGO:00102561470.025
negative regulation of cellular component organizationGO:00511291940.025
multicellular organismal signalingGO:0035637910.025
regulation of hydrolase activityGO:00513362460.025
response to organic cyclic compoundGO:00140701980.025
immune effector processGO:00022523210.025
nucleoside phosphate metabolic processGO:00067533380.025
positive regulation of cell developmentGO:00107202370.025
germ cell developmentGO:00072811850.025
posttranscriptional regulation of gene expressionGO:00106081550.025
regulation of system processGO:00440572000.025
inorganic cation transmembrane transportGO:00986622070.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.024
cell adhesionGO:00071553290.024
regulation of secretion by cellGO:19035302490.024
cellular response to acid chemicalGO:0071229680.024
organelle localizationGO:00516401790.024
myeloid cell differentiationGO:00300992330.024
regulation of establishment of protein localizationGO:00702011810.024
protein secretionGO:00093061110.024
nuclear transportGO:00511691390.024
single organism cell adhesionGO:00986021560.024
mapk cascadeGO:00001652810.023
muscle system processGO:00030121410.023
regulation of apoptotic signaling pathwayGO:20012331970.023
regulation of purine nucleotide metabolic processGO:19005421690.023
negative regulation of protein metabolic processGO:00512482820.023
organic anion transportGO:00157111370.023
purine nucleotide metabolic processGO:00061633020.023
muscle contractionGO:00069361010.023
cell activation involved in immune responseGO:00022631260.023
asymmetric stem cell divisionGO:009872230.023
ribose phosphate metabolic processGO:00196932910.022
intracellular protein transportGO:00068862040.022
circulatory system processGO:00030131970.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
nucleoside metabolic processGO:00091162460.022
innate immune responseGO:00450871570.022
small molecule biosynthetic processGO:00442831320.022
regulation of body fluid levelsGO:00508781620.022
protein localization to organelleGO:00333651850.022
protein maturationGO:00516041760.022
cellular response to organonitrogen compoundGO:00714171450.022
heterocycle catabolic processGO:00467002800.022
blood circulationGO:00080151950.021
morphogenesis of a branching epitheliumGO:00611381930.021
telencephalon developmentGO:00215371860.021
cellular protein complex assemblyGO:00436231160.021
regulation of ossificationGO:00302781120.021
regulation of cell activationGO:00508652890.021
microtubule cytoskeleton organizationGO:00002261570.021
cellular calcium ion homeostasisGO:00068741190.021
negative regulation of molecular functionGO:00440922580.021
alcohol metabolic processGO:00060661160.021
response to lipopolysaccharideGO:00324961280.021
cellular response to lipidGO:00713961450.021
regulation of synaptic growth at neuromuscular junctionGO:000858240.021
tube formationGO:00351481400.021
positive regulation of nervous system developmentGO:00519622210.021
locomotory behaviorGO:00076261950.021
regulation of cell migrationGO:00303342190.021
negative regulation of immune system processGO:00026832090.021
cellular nitrogen compound catabolic processGO:00442702800.021
protein localization to membraneGO:00726571080.021
regulation of protein kinase activityGO:00458592320.020
central nervous system neuron differentiationGO:00219531620.020
blood vessel morphogenesisGO:00485142850.020
ossificationGO:00015032160.020
organophosphate biosynthetic processGO:00904071220.020
negative regulation of phosphate metabolic processGO:00459361840.020
negative regulation of cellular protein metabolic processGO:00322692470.020
epithelial tube morphogenesisGO:00605623030.020
epithelial cell proliferationGO:00506731740.020
regulation of ion transportGO:00432692150.020
t cell differentiationGO:00302171740.020
nucleocytoplasmic transportGO:00069131390.020
multi multicellular organism processGO:00447061090.020
peptidyl amino acid modificationGO:00181933360.020
regulation of secretionGO:00510462740.020
organic acid transportGO:00158491010.020
positive regulation of neuron differentiationGO:00456661410.019
regulation of ion transmembrane transportGO:00347651190.019
protein localization to plasma membraneGO:0072659570.019
fat cell differentiationGO:00454441600.019
transmission of nerve impulseGO:0019226760.019
regulation of inflammatory responseGO:00507271470.019
cellular lipid metabolic processGO:00442553230.019
anatomical structure homeostasisGO:00602491450.019
purine nucleoside metabolic processGO:00422782410.019
positive regulation of cytokine productionGO:00018191740.019
metal ion homeostasisGO:00550651890.019
gliogenesisGO:00420631410.018
nucleotide catabolic processGO:00091662170.018
nucleoside phosphate catabolic processGO:19012922220.018
ribonucleotide metabolic processGO:00092592910.018
regulation of protein transportGO:00512231630.018
sensory organ morphogenesisGO:00905962420.018
regulation of kinase activityGO:00435492490.018
cellular divalent inorganic cation homeostasisGO:00725031270.018
regulation of epithelial cell proliferationGO:00506781410.018
leukocyte activation involved in immune responseGO:00023661260.018
regulation of proteolysisGO:00301621640.018
muscle tissue developmentGO:00605373080.018
microtubule based processGO:00070172360.018
aromatic compound catabolic processGO:00194392860.018
positive regulation of lymphocyte activationGO:00512511400.018
rap protein signal transductionGO:003248630.018
neuron migrationGO:00017641220.018
heart processGO:0003015940.017
positive regulation of transferase activityGO:00513471670.017
mitotic cell cycle processGO:19030471590.017
b cell activationGO:00421131610.017
positive regulation of cell activationGO:00508671580.017
striated muscle tissue developmentGO:00147062930.017
nucleoside triphosphate catabolic processGO:00091432050.017
cardiac muscle tissue developmentGO:00487381300.017
divalent inorganic cation transportGO:00725111780.017
positive regulation of defense responseGO:00313491240.017
calcium ion transportGO:00068161590.017
regulation of cell morphogenesis involved in differentiationGO:00107691510.017
glycerolipid metabolic processGO:00464861220.017
epithelial cell developmentGO:00020641590.017
ribonucleoside catabolic processGO:00424542060.017
sequestering of metal ionGO:0051238190.017
regulation of transmembrane transportGO:00347621280.017
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.017
cell fate commitmentGO:00451652100.017
carboxylic acid transportGO:00469421000.017
nucleoside triphosphate metabolic processGO:00091412300.016
protein ubiquitinationGO:00165671710.016
positive regulation of apoptotic processGO:00430652170.016
regulation of cellular component sizeGO:00325351210.016
positive regulation of protein phosphorylationGO:00019342420.016
rho protein signal transductionGO:0007266320.016
response to acid chemicalGO:00011011110.016
divalent metal ion transportGO:00708381720.016
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.016
single organismal cell cell adhesionGO:00163371310.016
wnt signaling pathwayGO:00160551880.016
regulation of anatomical structure sizeGO:00900661780.016
production of molecular mediator of immune responseGO:00024401030.016
developmental maturationGO:00217001930.016
organic cyclic compound catabolic processGO:19013612950.016
regulation of cell divisionGO:0051302760.016
leukocyte proliferationGO:00706611720.016
regulation of interleukin 8 secretionGO:200048220.016
regulation of transferase activityGO:00513382630.016
sequestering of calcium ionGO:0051208180.016
muscle cell differentiationGO:00426922610.016
protein modification by small protein conjugationGO:00324461870.016
stem cell developmentGO:00488642190.016
regulation of leukocyte mediated immunityGO:00027031040.016
immune response regulating signaling pathwayGO:00027641250.016
establishment of organelle localizationGO:00516561220.016
organic hydroxy compound metabolic processGO:19016152030.016
regulation of innate immune responseGO:0045088910.016
positive regulation of cell deathGO:00109422240.016
negative regulation of protein modification processGO:00314001630.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
stem cell differentiationGO:00488632680.015
reactive nitrogen species metabolic processGO:200105700.015
cellular response to cytokine stimulusGO:00713451890.015
learning or memoryGO:00076111480.015
homeostasis of number of cellsGO:00488722100.015
angiogenesisGO:00015252010.015
purine ribonucleoside metabolic processGO:00461282410.015
lymphocyte differentiationGO:00300982420.015
response to nutrient levelsGO:00316671090.015
glycerophospholipid metabolic processGO:0006650710.015
camera type eye developmentGO:00430102660.015
meiotic nuclear divisionGO:00071261150.015
regulation of cellular catabolic processGO:00313292420.015
positive regulation of secretionGO:00510471300.015
cellular protein catabolic processGO:00442571550.015
response to radiationGO:00093141650.015
skeletal system morphogenesisGO:00487052030.015
protein modification by small protein conjugation or removalGO:00706472070.015
regulation of muscle system processGO:0090257800.015
cellular macromolecule catabolic processGO:00442652060.015
methylationGO:00322591340.015
regulation of metal ion transportGO:00109591060.015
lymphocyte activation involved in immune responseGO:0002285930.014
male anatomical structure morphogenesisGO:009059840.014
protein targetingGO:00066051430.014
regulation of cellular component biogenesisGO:00440871810.014
positive regulation of secretion by cellGO:19035321140.014
mitotic cell cycleGO:00002781950.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
regulation of nucleotide metabolic processGO:00061401690.014
glycosyl compound metabolic processGO:19016572460.014
calcium ion homeostasisGO:00550741270.014
peptide transportGO:00158331330.014
regulation of lymphocyte differentiationGO:00456191070.014
regulation of interleukin 8 productionGO:003267730.014
immune response activating signal transductionGO:00027571160.014
interleukin 8 secretionGO:007260630.014
morphogenesis of a branching structureGO:00017632030.014
canonical wnt signaling pathwayGO:00600701300.014
positive regulation of cellular catabolic processGO:00313311480.014
negative regulation of cell proliferationGO:00082852960.014
axonogenesisGO:00074092740.014
oocyte constructionGO:000730820.014
lipid biosynthetic processGO:00086101790.014
regulation of cytokine secretionGO:0050707610.014
cell divisionGO:00513011200.014
regulation of adaptive immune responseGO:0002819900.014
lymphocyte proliferationGO:00466511640.014
oocyte axis specificationGO:000730920.014
regulation of organelle organizationGO:00330432890.014
divalent inorganic cation homeostasisGO:00725071380.014
leukocyte mediated immunityGO:00024431740.014
synapse organizationGO:00508081250.014
regulation of interleukin 10 secretionGO:200117940.014
pallium developmentGO:00215431200.014
purine nucleoside catabolic processGO:00061522050.014
purine containing compound catabolic processGO:00725232130.014
regulation of homeostatic processGO:00328441820.014
Mouse
positive regulation of hydrolase activityGO:00513451480.014
regulation of blood circulationGO:1903522930.014
male sex differentiationGO:00466611090.014
regulation of cell cycle processGO:00105641600.014
protein localization to nucleusGO:00345041210.014
response to growth factorGO:00708481980.013
neuron deathGO:00709971540.013
ribonucleotide biosynthetic processGO:0009260590.013
cellular response to biotic stimulusGO:0071216920.013
positive regulation of cytosolic calcium ion concentrationGO:0007204650.013
reactive oxygen species biosynthetic processGO:190340980.013
regulation of cell adhesionGO:00301551540.013
regulation of canonical wnt signaling pathwayGO:0060828820.013
cellular response to molecule of bacterial originGO:0071219830.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
embryonic genitalia morphogenesisGO:003053840.013
morphogenesis of embryonic epitheliumGO:00163311590.013
neuron apoptotic processGO:00514021420.013
cell growthGO:00160491300.013
embryonic organ morphogenesisGO:00485622760.013
nuclear importGO:0051170950.013
nucleoside phosphate biosynthetic processGO:1901293790.013
purine ribonucleotide biosynthetic processGO:0009152590.013
reactive oxygen species metabolic processGO:0072593840.013
extracellular structure organizationGO:00430621480.013
gland developmentGO:00487323300.013
negative regulation of cell cycleGO:00457861230.013
positive regulation of protein transportGO:0051222930.013
ribonucleotide catabolic processGO:00092612080.013
macromolecule methylationGO:00434141200.013
purine nucleoside triphosphate metabolic processGO:00091442260.013
activation of immune responseGO:00022531380.013
organelle fissionGO:00482851700.013
positive regulation of kinase activityGO:00336741550.013
organonitrogen compound catabolic processGO:19015652640.013
regulation of neuron projection developmentGO:00109751690.013
negative regulation of wnt signaling pathwayGO:0030178730.013
defense response to other organismGO:00985421970.013
ear developmentGO:00435832000.013
ameboidal type cell migrationGO:00016671280.013
regulation of cell sizeGO:0008361720.013
cell recognitionGO:0008037830.013
tissue homeostasisGO:00018941150.013
glial cell differentiationGO:00100011310.013
hematopoietic progenitor cell differentiationGO:00022441430.013
purine ribonucleotide catabolic processGO:00091542080.013
myosin filament organizationGO:003103330.013
multicellular organismal homeostasisGO:00488711640.013
cytosolic calcium ion homeostasisGO:0051480700.013
glycosyl compound catabolic processGO:19016582060.012
sensory perception of soundGO:0007605970.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
glycoprotein metabolic processGO:00091001160.012
establishment of protein localization to organelleGO:00725941180.012
regulation of extent of cell growthGO:0061387520.012
rna interferenceGO:001624620.012
establishment or maintenance of neuroblast polarityGO:004519610.012
bone developmentGO:00603481200.012
regulation of high voltage gated calcium channel activityGO:190184120.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
male genitalia morphogenesisGO:004880840.012
modification dependent protein catabolic processGO:00199411330.012
negative regulation of organelle organizationGO:0010639900.012
adult locomotory behaviorGO:0008344910.012
regulation of wnt signaling pathwayGO:00301111230.012
adaptive immune responseGO:00022501550.012
protein processingGO:00164851630.012
regulation of vesicle mediated transportGO:00606271390.012
extracellular matrix organizationGO:00301981470.012
regulation of cell cycle phase transitionGO:1901987770.012
cytokine secretionGO:0050663720.012
endocytosisGO:00068971680.012
limb developmentGO:00601731660.012
interleukin 8 productionGO:003263740.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
organophosphate catabolic processGO:00464342320.012
purine containing compound biosynthetic processGO:0072522700.012
cellular response to lipopolysaccharideGO:0071222770.012
establishment of neuroblast polarityGO:004520010.012
positive regulation of innate immune responseGO:0045089800.012
b cell differentiationGO:0030183780.012
negative regulation of phosphorus metabolic processGO:00105631840.012
actin cytoskeleton organizationGO:00300362200.012
peptidyl tyrosine phosphorylationGO:00181081430.011
sensory perception of mechanical stimulusGO:00509541070.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
asymmetric neuroblast divisionGO:005505910.011
developmental growth involved in morphogenesisGO:00605601380.011
positive regulation of cell motilityGO:20001471160.011
positive regulation of immune effector processGO:00026991070.011
regulation of mitotic cell cycleGO:00073461260.011
meiotic cell cycleGO:00513211220.011
substantia nigra developmentGO:002176220.011
regulation of leukocyte apoptotic processGO:2000106560.011
Mouse
striated muscle myosin thick filament assemblyGO:007168810.011
interleukin 10 secretionGO:007260840.011
cerebral cortex developmentGO:0021987860.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
cellular response to hormone stimulusGO:00328701500.011
purine nucleotide catabolic processGO:00061952110.011
regulation of protein catabolic processGO:00421761080.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
regulation of blood pressureGO:0008217930.011
heart contractionGO:0060047930.011
neuronal action potentialGO:0019228540.011
positive regulation of intracellular transportGO:0032388700.011
regulation of hormone levelsGO:00108172110.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
exocytosisGO:00068871210.011
cell cell junction organizationGO:0045216720.011
protein importGO:00170381010.011
appendage morphogenesisGO:00351071490.011
spermatid developmentGO:00072861080.011
purine ribonucleoside catabolic processGO:00461302050.011
molting cycleGO:0042303900.011
spermatid differentiationGO:00485151150.011
fertilizationGO:00095661270.011
translationGO:0006412930.011
regulation of intracellular transportGO:00323861590.011
gonad developmentGO:00084061410.011
positive regulation of protein kinase activityGO:00458601440.011
single organism nuclear importGO:1902593950.011
cyclic nucleotide metabolic processGO:0009187590.011
regulation of ion homeostasisGO:2000021640.011
Mouse
epithelial cell morphogenesisGO:0003382410.011
response to inorganic substanceGO:0010035960.011
positive regulation of nucleotide metabolic processGO:00459811140.011
modification dependent macromolecule catabolic processGO:00436321330.011
detection of stimulusGO:0051606840.011
regulation of myeloid cell differentiationGO:0045637960.011
oxidation reduction processGO:00551143420.010
retina development in camera type eyeGO:00600411190.010
positive regulation of neuron projection developmentGO:0010976790.010
response to extracellular stimulusGO:00099911270.010
stem cell maintenanceGO:00198271300.010
regulation of cell projection organizationGO:00313442060.010
regulation of cellular response to growth factor stimulusGO:0090287820.010
regulation of t cell activationGO:00508631700.010
cellular response to transforming growth factor beta stimulusGO:0071560880.010
positive regulation of mapk cascadeGO:00434101700.010
nucleoside catabolic processGO:00091642060.010
negative regulation of cytokine productionGO:0001818840.010
myeloid leukocyte differentiationGO:00025731190.010
negative regulation of nervous system developmentGO:00519611560.010
regulation of interferon gamma productionGO:0032649570.010
adult behaviorGO:00305341350.010
sulfur compound metabolic processGO:00067901000.010
negative regulation of synapse assemblyGO:005196430.010
limb morphogenesisGO:00351081490.010
negative regulation of lymphocyte activationGO:0051250910.010
muscle cell developmentGO:00550011330.010
skin developmentGO:00435882200.010
myosin filament assemblyGO:003103420.010
appendage developmentGO:00487361660.010
regulation of cell growthGO:0001558910.010
regulation of muscle tissue developmentGO:1901861970.010
regulation of mitotic cell cycle phase transitionGO:1901990730.010
nuclear divisionGO:00002801580.010
ribonucleoside triphosphate catabolic processGO:00092031990.010
negative regulation of neuron apoptotic processGO:0043524920.010
blastocyst developmentGO:0001824800.010
positive regulation of apoptotic signaling pathwayGO:2001235950.010
regulation of lymphocyte mediated immunityGO:0002706840.010
establishment or maintenance of cytoskeleton polarityGO:003095220.010

Sh2d4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.013
disease of anatomical entityDOID:700.013
immune system diseaseDOID:291400.010