Mus musculus

32 known processes

Xrn2

5'-3' exoribonuclease 2

Xrn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.437
regulation of cell cycle processGO:00105641600.200
regulation of cellular component biogenesisGO:00440871810.188
dna metabolic processGO:00062593030.140
nuclear divisionGO:00002801580.127
regulation of organelle organizationGO:00330432890.126
dna repairGO:00062811070.125
meiotic cell cycleGO:00513211220.117
regulation of cell cycleGO:00517262810.105
chromatin organizationGO:00063252060.104
cellular ketone metabolic processGO:0042180840.088
spermatogenesisGO:00072832840.083
chromosome organization involved in meiosisGO:0070192390.083
organelle fissionGO:00482851700.075
meiotic nuclear divisionGO:00071261150.074
germ cell developmentGO:00072811850.069
organophosphate catabolic processGO:00464342320.067
regulation of cell divisionGO:0051302760.065
regulation of cellular ketone metabolic processGO:0010565660.064
gene silencing by rnaGO:0031047190.054
gonad developmentGO:00084061410.052
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.051
mitotic cell cycleGO:00002781950.051
mitotic cell cycle processGO:19030471590.051
rna processingGO:00063961050.050
development of primary sexual characteristicsGO:00451371430.048
microtubule cytoskeleton organizationGO:00002261570.048
regulation of chromatin modificationGO:1903308570.048
regulation of mrna processingGO:0050684410.046
regulation of cell activationGO:00508652890.046
posttranscriptional regulation of gene expressionGO:00106081550.045
oocyte axis specificationGO:000730920.045
cellular response to cytokine stimulusGO:00713451890.045
mrna metabolic processGO:0016071840.044
negative regulation of cellular component organizationGO:00511291940.041
ion transmembrane transportGO:00342203610.040
regulation of protein complex assemblyGO:0043254830.040
regulation of mitotic cell cycle phase transitionGO:1901990730.037
cellular amino acid metabolic processGO:00065201030.037
mrna processingGO:0006397630.037
rna interferenceGO:001624620.036
male gamete generationGO:00482322850.036
regulation of mitotic cell cycleGO:00073461260.036
negative regulation of cell cycleGO:00457861230.036
cellular response to lipidGO:00713961450.036
regulation of lymphocyte activationGO:00512492400.035
g1 s transition of mitotic cell cycleGO:0000082570.035
response to radiationGO:00093141650.034
positive regulation of organelle organizationGO:00106381280.034
apoptotic signaling pathwayGO:00971903060.034
stem cell differentiationGO:00488632680.033
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000047910.032
stem cell developmentGO:00488642190.030
negative regulation of protein metabolic processGO:00512482820.030
maturation of 5 8s rrnaGO:000046010.030
regulation of lymphocyte proliferationGO:00506701170.029
regulation of chromosome organizationGO:0033044830.028
regulation of cellular amine metabolic processGO:0033238200.027
modification dependent macromolecule catabolic processGO:00436321330.027
posttranscriptional gene silencingGO:0016441100.027
cellular amine metabolic processGO:0044106440.027
microtubule nucleationGO:000702020.026
microtubule based processGO:00070172360.026
positive regulation of apoptotic processGO:00430652170.025
cell divisionGO:00513011200.025
regulation of cellular response to stressGO:00801351590.025
regulation of cellular amino acid metabolic processGO:000652150.025
cellular response to gamma radiationGO:007148040.024
translationGO:0006412930.024
meiotic cell cycle processGO:1903046770.024
regulation of response to dna damage stimulusGO:2001020340.024
regulation of synaptic growth at neuromuscular junctionGO:000858240.023
intracellular mrna localizationGO:000829840.023
chromosome segregationGO:0007059480.023
regulation of chromatin organizationGO:1902275570.023
erythrocyte differentiationGO:0030218880.023
regulation of nuclear divisionGO:0051783560.023
histone lysine methylationGO:0034968500.023
organic cyclic compound catabolic processGO:19013612950.023
positive regulation of protein modification processGO:00314012990.023
mitotic nuclear divisionGO:0007067480.023
cellular response to radiationGO:0071478280.023
spermatid developmentGO:00072861080.023
lymphocyte proliferationGO:00466511640.022
homeostasis of number of cellsGO:00488722100.022
ossificationGO:00015032160.022
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.022
nucleoside monophosphate metabolic processGO:0009123850.022
negative regulation of immune system processGO:00026832090.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
negative regulation of leukocyte proliferationGO:0070664460.022
rna localizationGO:0006403230.021
positive regulation of lymphocyte activationGO:00512511400.021
positive regulation of apoptotic signaling pathwayGO:2001235950.021
ncrna processingGO:0034470260.021
compound eye developmentGO:004874910.021
inflammatory responseGO:00069542440.021
cellularizationGO:000734910.021
regulation of cell cycle phase transitionGO:1901987770.021
negative regulation of organelle organizationGO:0010639900.021
positive regulation of cellular amine metabolic processGO:003324050.020
ribose phosphate metabolic processGO:00196932910.020
negative regulation of cellular protein metabolic processGO:00322692470.020
peptidyl amino acid modificationGO:00181933360.020
positive regulation of cell cycle processGO:0090068610.020
myeloid cell differentiationGO:00300992330.020
nucleic acid phosphodiester bond hydrolysisGO:0090305490.020
aromatic compound catabolic processGO:00194392860.020
regulation of bindingGO:00510981110.020
carbohydrate derivative catabolic processGO:19011362310.019
response to organic cyclic compoundGO:00140701980.019
protein localization to organelleGO:00333651850.019
oocyte constructionGO:000730820.019
organic hydroxy compound metabolic processGO:19016152030.019
synapse organizationGO:00508081250.019
regulation of meiotic cell cycleGO:0051445340.019
rna splicing via transesterification reactionsGO:0000375430.018
heterochromatin organizationGO:007082840.018
nucleotide metabolic processGO:00091173320.018
regulation of neuron deathGO:19012141340.018
regulation of mrna splicing via spliceosomeGO:0048024320.018
amine metabolic processGO:0009308450.018
regulation of system processGO:00440572000.018
cellular homeostasisGO:00197252400.018
nitrogen compound transportGO:00717052710.017
chromatin modificationGO:00165681870.017
regulation of apoptotic signaling pathwayGO:20012331970.017
nucleoside phosphate metabolic processGO:00067533380.017
response to acid chemicalGO:00011011110.017
intrinsic apoptotic signaling pathwayGO:00971931320.017
leukocyte differentiationGO:00025213420.016
leukocyte proliferationGO:00706611720.016
protein importGO:00170381010.016
rna splicingGO:0008380540.016
microtubule organizing center organizationGO:0031023280.016
negative regulation of protein processingGO:0010955790.016
nuclear importGO:0051170950.016
response to organonitrogen compoundGO:00102432460.016
positive regulation of transferase activityGO:00513471670.016
ribonucleotide catabolic processGO:00092612080.016
mitotic chromosome condensationGO:000707610.016
regulation of homeostatic processGO:00328441820.016
regulation of cellular catabolic processGO:00313292420.015
sensory perceptionGO:00076002450.015
ribonucleotide metabolic processGO:00092592910.015
regulation of kinase activityGO:00435492490.015
nuclear transportGO:00511691390.015
response to light stimulusGO:00094161350.015
actin cytoskeleton organizationGO:00300362200.015
protein localization to nucleusGO:00345041210.015
extracellular structure organizationGO:00430621480.015
purine ribonucleotide metabolic processGO:00091502900.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
ribonucleoside catabolic processGO:00424542060.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
spermatid differentiationGO:00485151150.015
regulation of protein localizationGO:00328802310.015
protein ubiquitinationGO:00165671710.015
cation transmembrane transportGO:00986552660.015
dna packagingGO:0006323300.015
negative regulation of lymphocyte activationGO:0051250910.015
cellular response to abiotic stimulusGO:0071214560.015
cytokine productionGO:00018163190.015
lipid localizationGO:00108761260.014
positive regulation of cellular catabolic processGO:00313311480.014
organonitrogen compound catabolic processGO:19015652640.014
leukocyte apoptotic processGO:0071887710.014
regulation of lipid storageGO:0010883200.014
maintenance of locationGO:0051235890.014
positive regulation of cell deathGO:00109422240.014
positive regulation of homeostatic processGO:0032846640.014
positive regulation of nervous system developmentGO:00519622210.014
male meiosisGO:0007140370.014
cellular nitrogen compound catabolic processGO:00442702800.014
negative regulation of molecular functionGO:00440922580.014
bone developmentGO:00603481200.014
developmental maturationGO:00217001930.014
nuclear membrane organizationGO:007176340.014
regulation of hydrolase activityGO:00513362460.014
positive regulation of programmed cell deathGO:00430682180.014
oocyte anterior posterior axis specificationGO:000731420.013
cation transportGO:00068123990.013
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.013
t cell activationGO:00421102890.013
hematopoietic progenitor cell differentiationGO:00022441430.013
multi multicellular organism processGO:00447061090.013
muscle cell differentiationGO:00426922610.013
centrosome separationGO:005129940.013
nucleobase containing small molecule metabolic processGO:00550863520.013
inorganic cation transmembrane transportGO:00986622070.013
protein modification by small protein conjugation or removalGO:00706472070.013
rhythmic processGO:00485111740.012
negative regulation of cell activationGO:00508661110.012
carbohydrate derivative biosynthetic processGO:19011371830.012
histone modificationGO:00165701590.012
regulation of leukocyte proliferationGO:00706631210.012
nucleotide catabolic processGO:00091662170.012
nucleobase containing compound transportGO:0015931270.012
regulation of transferase activityGO:00513382630.012
lymphocyte differentiationGO:00300982420.012
positive regulation of mitotic cell cycleGO:0045931410.012
action potentialGO:0001508780.012
wound healingGO:00420601570.012
locomotory behaviorGO:00076261950.012
oocyte developmentGO:0048599330.012
lipid storageGO:0019915360.012
regulation of engulfment of apoptotic cellGO:190107420.012
transmembrane transportGO:00550854120.012
protein import into nucleusGO:0006606950.012
developmental growth involved in morphogenesisGO:00605601380.012
membrane organizationGO:00610242450.012
cation homeostasisGO:00550802120.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
response to uvGO:0009411440.011
cellular protein catabolic processGO:00442571550.011
organic anion transportGO:00157111370.011
response to inorganic substanceGO:0010035960.011
cell matrix adhesionGO:0007160680.011
signal transduction by p53 class mediatorGO:0072331510.011
positive regulation of protein phosphorylationGO:00019342420.011
protein processingGO:00164851630.011
ribosomal small subunit biogenesisGO:004227440.011
meiosis iGO:0007127600.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
nucleoside triphosphate metabolic processGO:00091412300.011
regulation of response to woundingGO:19030341890.011
methylationGO:00322591340.011
female gamete generationGO:0007292740.011
protein oligomerizationGO:0051259670.011
protein autophosphorylationGO:0046777610.010
purine nucleotide metabolic processGO:00061633020.010
genitalia developmentGO:0048806370.010
protein polyubiquitinationGO:0000209330.010
rna 5 end processingGO:000096610.010
male sex differentiationGO:00466611090.010
purine ribonucleotide catabolic processGO:00091542080.010
anatomical structure homeostasisGO:00602491450.010
regulation of inflammatory responseGO:00507271470.010
negative regulation of cellular amine metabolic processGO:003323910.010
regulation of rna splicingGO:0043484370.010
cell substrate adhesionGO:00315891300.010
negative regulation of neuron differentiationGO:00456651010.010
neural tube developmentGO:00219151600.010
neuronal action potentialGO:0019228540.010
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.010
cellular response to organic cyclic compoundGO:0071407870.010
regulation of cytoskeleton organizationGO:00514931220.010
negative regulation of proteolysisGO:0045861740.010
single organism nuclear importGO:1902593950.010

Xrn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.061
nervous system diseaseDOID:86300.061
eye diseaseDOID:561400.021
sensory system diseaseDOID:005015500.021
eye and adnexa diseaseDOID:149200.021
central nervous system diseaseDOID:33100.018
neurodegenerative diseaseDOID:128900.016
retinal diseaseDOID:567900.016
retinal degenerationDOID:846600.014
kidney diseaseDOID:55700.010
urinary system diseaseDOID:1800.010
nephritisDOID:1095200.010