IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Cxcr3

chemokine (C-X-C motif) receptor 3

(Aliases: Cd183,Cmkar3)

Entrez: 12766
Ensembl: ENSMUSG00000050232
UniProtKB: O88410

Process Predictions
Disease Predictions

Cxcr3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
immune effector process	GO:0002252	321	0.777	Mouse
defense response to other organism	GO:0098542	197	0.758
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.736	Mouse
leukocyte mediated immunity	GO:0002443	174	0.699	Mouse
sequestering of calcium ion	GO:0051208	18	0.680	Mouse
innate immune response	GO:0045087	157	0.596	Mouse
negative thymic t cell selection	GO:0045060	12	0.587	Mouse
adaptive immune response	GO:0002250	155	0.568	Mouse
negative regulation of eosinophil degranulation	GO:0043310	1	0.554	Mouse
cytokine production	GO:0001816	319	0.541	Human Mouse
regulation of ion homeostasis	GO:2000021	64	0.500	Human Mouse
regulation of defense response	GO:0031347	233	0.500	Mouse
lymphocyte differentiation	GO:0030098	242	0.497	Mouse
membrane organization	GO:0061024	245	0.464	Mouse
thymic t cell selection	GO:0045061	22	0.463	Mouse
leukocyte migration	GO:0050900	124	0.425	Mouse Rat
regulation of cell activation	GO:0050865	289	0.420	Mouse
positive regulation of interferon gamma production	GO:0032729	39	0.419	Mouse
leukocyte proliferation	GO:0070661	172	0.416	Mouse
positive regulation of protein phosphorylation	GO:0001934	242	0.392
eosinophil activation	GO:0043307	1	0.388	Mouse
negative regulation of immune system process	GO:0002683	209	0.380	Mouse
cation transport	GO:0006812	399	0.364	Human Mouse
positive regulation of tumor necrosis factor superfamily cytokine production	GO:1903557	31	0.360	Mouse
myeloid leukocyte mediated immunity	GO:0002444	42	0.359	Mouse
metal ion homeostasis	GO:0055065	189	0.338	Human Mouse Rat
positive regulation of monocyte chemotaxis	GO:0090026	2	0.336	Mouse
response to molecule of bacterial origin	GO:0002237	143	0.326	Mouse
chemotaxis	GO:0006935	247	0.322	Human Mouse Rat
regulation of adaptive immune response	GO:0002819	90	0.321	Mouse
interleukin 12 secretion	GO:0072610	3	0.318	Mouse
stimulatory c type lectin receptor signaling pathway	GO:0002223	2	0.308
regulation of cellular amine metabolic process	GO:0033238	20	0.298
regulation of protein kinase activity	GO:0045859	232	0.297
negative t cell selection	GO:0043383	13	0.296	Mouse
morphogenesis of a branching structure	GO:0001763	203	0.290	Mouse
positive regulation of cd8 positive alpha beta t cell extravasation	GO:2000451	2	0.290	Mouse
mature dendritic cell differentiation	GO:0097029	3	0.289	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.288
leukocyte differentiation	GO:0002521	342	0.287	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.286
cation homeostasis	GO:0055080	212	0.284	Human Mouse Rat
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.284	Mouse
regulation of lymphocyte proliferation	GO:0050670	117	0.275	Mouse
cellular amine metabolic process	GO:0044106	44	0.272
regulation of interferon gamma production	GO:0032649	57	0.271	Mouse
positive regulation of cell activation	GO:0050867	158	0.269	Mouse
cytosolic calcium ion transport	GO:0060401	48	0.269	Human Mouse
positive regulation of t cell receptor signaling pathway	GO:0050862	4	0.268	Mouse
g protein coupled receptor signaling pathway	GO:0007186	243	0.268	Human Mouse Rat
regulated secretory pathway	GO:0045055	32	0.266	Mouse
cell killing	GO:0001906	67	0.265
t cell costimulation	GO:0031295	14	0.264	Mouse
regulation of vesicle mediated transport	GO:0060627	139	0.263	Mouse
positive regulation of protein modification process	GO:0031401	299	0.263
interleukin 2 production	GO:0032623	33	0.261	Mouse
angiogenesis	GO:0001525	201	0.257	Human Mouse
regulation of monocyte extravasation	GO:2000437	2	0.253	Mouse
regulation of immunological synapse formation	GO:2000520	2	0.243	Mouse
positive regulation of cytokine production	GO:0001819	174	0.241	Mouse
inflammatory response	GO:0006954	244	0.240	Mouse
positive regulation of lymphocyte activation	GO:0051251	140	0.239	Mouse
regulation of lymphocyte activation	GO:0051249	240	0.238	Mouse
lymphocyte proliferation	GO:0046651	164	0.238	Mouse
cellular calcium ion homeostasis	GO:0006874	119	0.238	Human Mouse Rat
myeloid cell differentiation	GO:0030099	233	0.234	Mouse
t cell selection	GO:0045058	34	0.233	Mouse
inner cell mass cell proliferation	GO:0001833	15	0.232
germ cell development	GO:0007281	185	0.229	Mouse
positive regulation of t cell activation	GO:0050870	101	0.229	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.229
regulation of cytokine production	GO:0001817	266	0.228	Mouse
cell chemotaxis	GO:0060326	81	0.225	Mouse Rat
regulation of monocyte chemotaxis	GO:0090025	3	0.223	Mouse
positive regulation of kinase activity	GO:0033674	155	0.222
cytokine secretion	GO:0050663	72	0.216	Mouse
regulation of angiogenesis	GO:0045765	81	0.213	Human Mouse
peptidyl amino acid modification	GO:0018193	336	0.212
cell cell recognition	GO:0009988	44	0.209	Mouse
granulocyte chemotaxis	GO:0071621	39	0.207	Mouse
anatomical structure homeostasis	GO:0060249	145	0.206
regulation of leukocyte mediated immunity	GO:0002703	104	0.206	Mouse
amine metabolic process	GO:0009308	45	0.204
regulation of t cell activation	GO:0050863	170	0.202	Mouse
divalent inorganic cation transport	GO:0072511	178	0.201	Human Mouse
immune response activating signal transduction	GO:0002757	116	0.197	Mouse
leukocyte chemotaxis	GO:0030595	69	0.197	Mouse Rat
calcium mediated signaling	GO:0019722	46	0.195	Rat
positive regulation of t cell costimulation	GO:2000525	2	0.194	Mouse
t cell differentiation in thymus	GO:0033077	77	0.193	Mouse
regulation of tumor necrosis factor superfamily cytokine production	GO:1903555	50	0.192	Mouse
positive regulation of immunological synapse formation	GO:2000522	1	0.192	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.190
helper t cell chemotaxis	GO:0035704	1	0.188	Mouse
response to lipopolysaccharide	GO:0032496	128	0.186	Mouse
release of sequestered calcium ion into cytosol	GO:0051209	42	0.184	Human Mouse
defense response to bacterium	GO:0042742	119	0.183
cell recognition	GO:0008037	83	0.181	Mouse
regulation of transferase activity	GO:0051338	263	0.179
t cell activation	GO:0042110	289	0.177	Mouse
monocyte extravasation	GO:0035696	2	0.174	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.169
multicellular organismal homeostasis	GO:0048871	164	0.161
regulation of calcium mediated signaling	GO:0050848	19	0.160
regulation of cell migration	GO:0030334	219	0.160	Mouse
antigen receptor mediated signaling pathway	GO:0050851	64	0.157	Mouse
divalent inorganic cation homeostasis	GO:0072507	138	0.156	Human Mouse Rat
muscle cell differentiation	GO:0042692	261	0.155
regulation of t cell costimulation	GO:2000523	2	0.154	Mouse
extrinsic apoptotic signaling pathway	GO:0097191	126	0.149	Mouse
immune response regulating signaling pathway	GO:0002764	125	0.147	Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.142	Mouse
negative regulation of defense response	GO:0031348	77	0.141	Mouse
rho protein signal transduction	GO:0007266	32	0.140
positive regulation of cellular amine metabolic process	GO:0033240	5	0.138
regulation of inflammatory response to antigenic stimulus	GO:0002861	21	0.138	Mouse
regulation of antigen receptor mediated signaling pathway	GO:0050854	29	0.137	Mouse
regulation of immune complex clearance by monocytes and macrophages	GO:0090264	2	0.135	Mouse
positive regulation of t cell proliferation	GO:0042102	52	0.134	Mouse
regulation of dendritic cell chemotaxis	GO:2000508	1	0.133	Mouse
regulation of cytokine secretion	GO:0050707	61	0.131	Mouse
nucleotide metabolic process	GO:0009117	332	0.131	Human
regulation of kinase activity	GO:0043549	249	0.130
cellular lipid metabolic process	GO:0044255	323	0.129
regulation of cell motility	GO:2000145	236	0.129	Mouse
regulation of chemotaxis	GO:0050920	53	0.129	Human Mouse
calcium ion homeostasis	GO:0055074	127	0.129	Human Mouse Rat
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation	GO:2000526	1	0.129	Mouse
blood vessel morphogenesis	GO:0048514	285	0.128	Human Mouse
cellular extravasation	GO:0045123	17	0.127	Mouse
leukocyte activation involved in immune response	GO:0002366	126	0.126	Mouse
cellular homeostasis	GO:0019725	240	0.126	Human Mouse Rat
signal transduction in absence of ligand	GO:0038034	55	0.126	Mouse
apoptotic signaling pathway	GO:0097190	306	0.126	Mouse
cellular ion homeostasis	GO:0006873	165	0.125	Human Mouse Rat
chemokine mediated signaling pathway	GO:0070098	17	0.125	Mouse Rat
cellular response to biotic stimulus	GO:0071216	92	0.122
positive t cell selection	GO:0043368	23	0.121
reactive oxygen species metabolic process	GO:0072593	84	0.121
regulation of leukocyte apoptotic process	GO:2000106	56	0.121	Mouse
mapk cascade	GO:0000165	281	0.120
regulation of alpha beta t cell activation	GO:0046634	53	0.119	Mouse
muscle tissue development	GO:0060537	308	0.117
eosinophil activation involved in immune response	GO:0002278	1	0.113	Mouse
epithelial tube morphogenesis	GO:0060562	303	0.111	Mouse
regulation of phagocytosis	GO:0050764	33	0.110
hematopoietic stem cell migration	GO:0035701	1	0.109	Mouse
regulation of leukocyte proliferation	GO:0070663	121	0.109	Mouse
telencephalon development	GO:0021537	186	0.109	Mouse
axon guidance	GO:0007411	141	0.108	Mouse
lymphocyte costimulation	GO:0031294	15	0.108	Mouse
regulation of endocytosis	GO:0030100	69	0.106
sensory perception of pain	GO:0019233	47	0.105	Mouse
leukocyte degranulation	GO:0043299	27	0.105	Mouse
telencephalon cell migration	GO:0022029	55	0.103	Mouse
defense response to gram positive bacterium	GO:0050830	50	0.103
microglial cell activation	GO:0001774	3	0.102	Mouse
positive regulation of cell migration	GO:0030335	109	0.100	Mouse
regulation of neutrophil migration	GO:1902622	14	0.100	Mouse
calcium ion transport	GO:0006816	159	0.100	Human Mouse
positive regulation of cell motility	GO:2000147	116	0.100	Mouse
cellular ketone metabolic process	GO:0042180	84	0.100
regulation of response to wounding	GO:1903034	189	0.099	Mouse
positive regulation of immune effector process	GO:0002699	107	0.099	Mouse
maintenance of location	GO:0051235	89	0.098	Mouse
immune complex clearance by monocytes and macrophages	GO:0002436	2	0.097	Mouse
regulation of map kinase activity	GO:0043405	120	0.097
t cell differentiation	GO:0030217	174	0.097	Mouse
cellular metal ion homeostasis	GO:0006875	151	0.097	Human Mouse Rat
ameboidal type cell migration	GO:0001667	128	0.097	Mouse
homeostasis of number of cells	GO:0048872	210	0.097
gamma delta t cell lineage commitment	GO:0002365	1	0.096
positive regulation of calcium mediated signaling	GO:0050850	15	0.095
cerebral cortex cell migration	GO:0021795	44	0.095	Mouse
regulation of tumor necrosis factor production	GO:0032680	49	0.094	Mouse
positive regulation of leukocyte mediated immunity	GO:0002705	70	0.094
neural precursor cell proliferation	GO:0061351	121	0.093	Mouse
glycoprotein metabolic process	GO:0009100	116	0.092	Mouse
nitrogen compound transport	GO:0071705	271	0.092
regulation of protein secretion	GO:0050708	82	0.092	Mouse
glycoprotein biosynthetic process	GO:0009101	89	0.092	Mouse
innate immune response activating cell surface receptor signaling pathway	GO:0002220	4	0.090
positive regulation of alpha beta t cell proliferation	GO:0046641	12	0.090	Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.090	Mouse
myeloid cell activation involved in immune response	GO:0002275	34	0.090	Mouse
positive regulation of protein kinase activity	GO:0045860	144	0.090
response to molecule of fungal origin	GO:0002238	4	0.090
lymphocyte migration	GO:0072676	26	0.089	Mouse Rat
cell adhesion	GO:0007155	329	0.089
branching morphogenesis of an epithelial tube	GO:0048754	159	0.088	Mouse
regulation of eosinophil degranulation	GO:0043309	1	0.088	Mouse
extrinsic apoptotic signaling pathway in absence of ligand	GO:0097192	55	0.087	Mouse
lymphocyte mediated immunity	GO:0002449	139	0.087
positive regulation of dendritic cell chemotaxis	GO:2000510	1	0.087	Mouse
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation	GO:2000721	2	0.086
peptidyl tyrosine modification	GO:0018212	145	0.085
endocytosis	GO:0006897	168	0.085
neuron projection guidance	GO:0097485	141	0.084	Mouse
regulation of mapk cascade	GO:0043408	248	0.084
cytosolic calcium ion homeostasis	GO:0051480	70	0.084	Human Mouse Rat
regulation of secretion by cell	GO:1903530	249	0.083	Mouse
exocytosis	GO:0006887	121	0.082	Mouse
neuron migration	GO:0001764	122	0.081	Mouse
alpha beta t cell activation	GO:0046631	91	0.080	Mouse
regulation of neutrophil chemotaxis	GO:0090022	14	0.080	Mouse
regulation of innate immune response	GO:0045088	91	0.080	Mouse
t cell migration	GO:0072678	19	0.079	Mouse Rat
negative regulation of phosphorylation	GO:0042326	166	0.079
t helper 17 cell chemotaxis	GO:0035705	1	0.078	Mouse
organelle fission	GO:0048285	170	0.078
positive regulation of leukocyte mediated cytotoxicity	GO:0001912	31	0.078
negative regulation of growth	GO:0045926	99	0.077
negative regulation of immune effector process	GO:0002698	55	0.076	Mouse
sensory perception	GO:0007600	245	0.076	Mouse
aromatic compound catabolic process	GO:0019439	286	0.076
antigen processing and presentation	GO:0019882	47	0.076	Mouse
tumor necrosis factor production	GO:0032640	50	0.075	Mouse
cell surface pattern recognition receptor signaling pathway	GO:0002752	2	0.075
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.074	Human Mouse Rat
negative regulation of intracellular signal transduction	GO:1902532	167	0.074
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.072
cell activation involved in immune response	GO:0002263	126	0.072	Mouse
myeloid leukocyte migration	GO:0097529	57	0.070	Mouse
striated muscle tissue development	GO:0014706	293	0.070
regulation of antigen processing and presentation	GO:0002577	10	0.070	Mouse
ras protein signal transduction	GO:0007265	77	0.070
sequestering of metal ion	GO:0051238	19	0.069	Mouse
single organism cell adhesion	GO:0098602	156	0.069
positive regulation of t cell extravasation	GO:2000409	2	0.069	Mouse
myeloid leukocyte differentiation	GO:0002573	119	0.069
tissue homeostasis	GO:0001894	115	0.068
alpha beta t cell proliferation	GO:0046633	21	0.068	Mouse
negative regulation of cell proliferation	GO:0008285	296	0.068	Human
positive regulation of lymphocyte proliferation	GO:0050671	70	0.067	Mouse
positive regulation of alpha beta t cell activation	GO:0046635	39	0.067	Mouse
microglia development	GO:0014005	2	0.067
neutrophil chemotaxis	GO:0030593	36	0.066	Mouse
regulation of organelle organization	GO:0033043	289	0.065
cell fate commitment	GO:0045165	210	0.065
regulation of cellular response to stress	GO:0080135	159	0.064
t cell receptor signaling pathway	GO:0050852	46	0.063	Mouse
regulation of leukocyte degranulation	GO:0043300	20	0.063	Mouse
b cell proliferation	GO:0042100	53	0.063
positive regulation of monocyte extravasation	GO:2000439	1	0.063	Mouse
regulation of cell killing	GO:0031341	40	0.062
b cell activation	GO:0042113	161	0.062
regulation of inflammatory response	GO:0050727	147	0.062	Mouse
regulation of lymphocyte anergy	GO:0002911	4	0.061
single organismal cell cell adhesion	GO:0016337	131	0.061
embryonic organ morphogenesis	GO:0048562	276	0.060
positive regulation of mapk cascade	GO:0043410	170	0.060
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.060
reactive oxygen species biosynthetic process	GO:1903409	8	0.060
regulation of hormone levels	GO:0010817	211	0.060
microglial cell activation involved in immune response	GO:0002282	1	0.060	Mouse
neutrophil mediated immunity	GO:0002446	19	0.059
regulation of canonical wnt signaling pathway	GO:0060828	82	0.058
glial cell differentiation	GO:0010001	131	0.058	Mouse
calcium ion transport into cytosol	GO:0060402	48	0.058	Human Mouse
axonogenesis	GO:0007409	274	0.057	Mouse
positive regulation of nervous system development	GO:0051962	221	0.057	Mouse
cell type specific apoptotic process	GO:0097285	268	0.057	Mouse
regulation of interleukin 2 production	GO:0032663	28	0.056	Mouse
production of molecular mediator of immune response	GO:0002440	103	0.056
positive regulation of granulocyte chemotaxis	GO:0071624	12	0.055	Mouse
positive regulation of behavior	GO:0048520	40	0.055	Human Mouse
positive regulation of hematopoietic stem cell migration	GO:2000473	1	0.055	Mouse
regulation of alpha beta t cell proliferation	GO:0046640	18	0.055	Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002824	61	0.055	Mouse
regulation of leukocyte mediated cytotoxicity	GO:0001910	38	0.054
cd8 positive alpha beta t cell extravasation	GO:0035697	3	0.054	Mouse
positive regulation of immune complex clearance by monocytes and macrophages	GO:0090265	2	0.054	Mouse
regulation of body fluid levels	GO:0050878	162	0.054
microglia differentiation	GO:0014004	2	0.054
pallium development	GO:0021543	120	0.054	Mouse
leukocyte mediated cytotoxicity	GO:0001909	62	0.053
negative regulation of synapse assembly	GO:0051964	3	0.053
macrophage activation	GO:0042116	27	0.053	Mouse
regulation of cytokine biosynthetic process	GO:0042035	59	0.053	Mouse
negative regulation of cellular component organization	GO:0051129	194	0.052
positive regulation of homeostatic process	GO:0032846	64	0.052	Human
forebrain development	GO:0030900	302	0.052	Mouse
regulation of establishment of protein localization	GO:0070201	181	0.052	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.052	Mouse
cognition	GO:0050890	149	0.052
activation of mapk activity	GO:0000187	59	0.052
regulation of cellular catabolic process	GO:0031329	242	0.051
granulocyte migration	GO:0097530	43	0.051	Mouse
positive regulation of natural killer cell mediated immunity	GO:0002717	16	0.051
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.051	Human Mouse Rat
regulation of homeostatic process	GO:0032844	182	0.051	Human Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.050	Human Mouse
positive regulation of innate immune response	GO:0045089	80	0.050
blood circulation	GO:0008015	195	0.050
granzyme mediated apoptotic signaling pathway	GO:0008626	1	0.050
natural killer cell activation	GO:0030101	44	0.049
innate immune response activating signal transduction	GO:0002758	50	0.049
interleukin 1 beta production	GO:0032611	30	0.048	Mouse
purine containing compound metabolic process	GO:0072521	311	0.048	Human
positive regulation of tumor necrosis factor production	GO:0032760	30	0.048	Mouse
labyrinthine layer development	GO:0060711	49	0.048
gliogenesis	GO:0042063	141	0.048	Mouse
positive regulation of lymphocyte anergy	GO:0002913	4	0.048
circulatory system process	GO:0003013	197	0.047
endothelial cell proliferation	GO:0001935	27	0.047	Human Mouse
interferon gamma production	GO:0032609	67	0.047	Mouse
interleukin 4 production	GO:0032633	24	0.047
regulation of mast cell activation involved in immune response	GO:0033006	17	0.047
cellular response to lipid	GO:0071396	145	0.046
regulation of cellular component biogenesis	GO:0044087	181	0.046
negative regulation of lymphocyte activation	GO:0051250	91	0.045
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.045
forebrain cell migration	GO:0021885	58	0.045	Mouse
divalent metal ion transport	GO:0070838	172	0.045	Human Mouse
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.045
detection of yeast	GO:0001879	2	0.045
cellular response to molecule of bacterial origin	GO:0071219	83	0.044
reactive nitrogen species metabolic process	GO:2001057	0	0.044
nucleobase containing small molecule metabolic process	GO:0055086	352	0.044	Human
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.043
positive regulation of endocytosis	GO:0045807	42	0.043
learning or memory	GO:0007611	148	0.043
positive regulation of cell death	GO:0010942	224	0.043	Human
regulation of phospholipase c activity	GO:1900274	3	0.043
dendritic cell chemotaxis	GO:0002407	7	0.042	Mouse
cell substrate adhesion	GO:0031589	130	0.042
regulation of apoptotic signaling pathway	GO:2001233	197	0.042	Mouse
regulation of cd8 positive alpha beta t cell extravasation	GO:2000449	3	0.042	Mouse
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.041	Mouse
cerebral cortex development	GO:0021987	86	0.041	Mouse
detection of stimulus	GO:0051606	84	0.041
positive regulation of defense response	GO:0031349	124	0.041	Mouse
carbohydrate derivative biosynthetic process	GO:1901137	183	0.041	Mouse
regulation of ras protein signal transduction	GO:0046578	114	0.041
positive regulation of neutrophil chemotaxis	GO:0090023	12	0.041	Mouse
cellular response to lipopolysaccharide	GO:0071222	77	0.040
interleukin 1 production	GO:0032612	31	0.040	Mouse
regulation of t cell extravasation	GO:2000407	3	0.040	Mouse
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.040
regulation of natural killer cell mediated immunity	GO:0002715	19	0.040
positive regulation of inflammatory response	GO:0050729	47	0.040	Mouse
eosinophil mediated immunity	GO:0002447	1	0.040	Mouse
ribose phosphate metabolic process	GO:0019693	291	0.040	Human
phagocytosis	GO:0006909	66	0.039
regulation of b cell proliferation	GO:0030888	39	0.039
cdc42 protein signal transduction	GO:0032488	0	0.039
mesodermal cell migration	GO:0008078	4	0.039
positive regulation of angiogenesis	GO:0045766	46	0.039	Human Mouse
membrane lipid metabolic process	GO:0006643	53	0.039
skeletal system development	GO:0001501	356	0.039
regionalization	GO:0003002	337	0.039
positive regulation of leukocyte proliferation	GO:0070665	73	0.038	Mouse
response to acid chemical	GO:0001101	111	0.038
negative regulation of vasculature development	GO:1901343	26	0.038	Human Mouse
blastocyst growth	GO:0001832	23	0.038
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process	GO:0045425	2	0.038
glycosyl compound metabolic process	GO:1901657	246	0.038
regulation of t cell anergy	GO:0002667	4	0.038
cytokine biosynthetic process	GO:0042089	68	0.038	Mouse
regulation of myeloid cell differentiation	GO:0045637	96	0.038
organic hydroxy compound metabolic process	GO:1901615	203	0.037
regulation of t cell proliferation	GO:0042129	92	0.037	Mouse
canonical wnt signaling pathway	GO:0060070	130	0.037
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.037
regulation of neuron projection development	GO:0010975	169	0.037
regulation of protein transport	GO:0051223	163	0.036	Mouse
regulation of erk1 and erk2 cascade	GO:0070372	71	0.036
positive regulation of neutrophil migration	GO:1902624	12	0.036	Mouse
establishment of organelle localization	GO:0051656	122	0.036
positive regulation of inflammatory response to antigenic stimulus	GO:0002863	11	0.036	Mouse
regulation of cell adhesion	GO:0030155	154	0.036
negative regulation of leukocyte degranulation	GO:0043301	7	0.035	Mouse
neuronal action potential	GO:0019228	54	0.035
digestive system development	GO:0055123	200	0.035
metanephric dct cell differentiation	GO:0072240	3	0.035
regulation of acute inflammatory response to antigenic stimulus	GO:0002864	10	0.035	Mouse
positive regulation of phospholipase c activity	GO:0010863	2	0.035
wnt signaling pathway	GO:0016055	188	0.035
tolerance induction	GO:0002507	14	0.035	Mouse
negative regulation of cell activation	GO:0050866	111	0.034	Mouse
neutrophil migration	GO:1990266	37	0.034	Mouse
regulation of b cell activation	GO:0050864	81	0.034
membrane invagination	GO:0010324	17	0.034
positive regulation of phagocytosis	GO:0050766	26	0.034
multicellular organismal signaling	GO:0035637	91	0.034
nucleoside triphosphate catabolic process	GO:0009143	205	0.034
cellular response to acid chemical	GO:0071229	68	0.034
regulation of podosome assembly	GO:0071801	3	0.034
cofactor transport	GO:0051181	4	0.034
regulation of ion transport	GO:0043269	215	0.034	Human
nucleoside phosphate metabolic process	GO:0006753	338	0.034	Human
regulation of actin filament based process	GO:0032970	99	0.033
regulation of myeloid leukocyte mediated immunity	GO:0002886	25	0.033	Mouse
t helper 1 type immune response	GO:0042088	25	0.033	Mouse
positive regulation of organelle organization	GO:0010638	128	0.033
positive regulation of phospholipase activity	GO:0010518	3	0.033
immunoglobulin mediated immune response	GO:0016064	69	0.033
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.033	Mouse
regulation of lymphocyte apoptotic process	GO:0070228	41	0.032
regulation of metal ion transport	GO:0010959	106	0.032	Human
regulation of vascular endothelial growth factor production	GO:0010574	13	0.032	Mouse
locomotory behavior	GO:0007626	195	0.032
negative regulation of homeostatic process	GO:0032845	71	0.032	Human Mouse
organelle localization	GO:0051640	179	0.032
endodermal cell fate specification	GO:0001714	4	0.032
renal system development	GO:0072001	225	0.032
endomembrane system organization	GO:0010256	147	0.032	Mouse
lymphocyte anergy	GO:0002249	4	0.032
guanosine containing compound metabolic process	GO:1901068	144	0.032
activation of innate immune response	GO:0002218	56	0.032
mitotic cell cycle	GO:0000278	195	0.032
fc receptor mediated inhibitory signaling pathway	GO:0002774	1	0.031
regulation of lymphocyte mediated immunity	GO:0002706	84	0.031
transmission of nerve impulse	GO:0019226	76	0.031
regulation of protein serine threonine kinase activity	GO:0071900	157	0.031
myeloid leukocyte activation	GO:0002274	83	0.031	Mouse
regulation of membrane potential	GO:0042391	192	0.031
positive regulation of map kinase activity	GO:0043406	84	0.031
macromolecule glycosylation	GO:0043413	55	0.031
regulation of hypersensitivity	GO:0002883	10	0.031	Mouse
organic cyclic compound catabolic process	GO:1901361	295	0.031
ribonucleoside catabolic process	GO:0042454	206	0.031
positive regulation of leukocyte degranulation	GO:0043302	10	0.030
negative regulation of ras protein signal transduction	GO:0046580	18	0.030
activation of immune response	GO:0002253	138	0.030	Mouse
vascular endothelial growth factor production	GO:0010573	13	0.030	Mouse
nucleotide catabolic process	GO:0009166	217	0.030
positive regulation of cell killing	GO:0031343	33	0.030
positive regulation of epithelial cell proliferation	GO:0050679	68	0.030	Mouse
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.030
positive regulation of chemotaxis	GO:0050921	38	0.030	Human Mouse
positive regulation of cell development	GO:0010720	237	0.029	Mouse
positive regulation of camp mediated signaling	GO:0043950	3	0.029	Human
cytokine metabolic process	GO:0042107	71	0.029	Mouse
erk1 and erk2 cascade	GO:0070371	77	0.029
positive regulation of b cell activation	GO:0050871	49	0.029
response to organonitrogen compound	GO:0010243	246	0.029
eosinophil degranulation	GO:0043308	1	0.029	Mouse
sphingosine 1 phosphate signaling pathway	GO:0003376	3	0.029
eosinophil migration	GO:0072677	3	0.029
nucleoside catabolic process	GO:0009164	206	0.029
negative regulation of leukocyte mediated immunity	GO:0002704	29	0.028	Mouse
cellular nitrogen compound catabolic process	GO:0044270	280	0.028
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.028
regulation of secretion	GO:0051046	274	0.028	Mouse
organonitrogen compound catabolic process	GO:1901565	264	0.028
regulation of calcium ion transport into cytosol	GO:0010522	31	0.028	Human
striated muscle cell development	GO:0055002	125	0.028
positive regulation of transferase activity	GO:0051347	167	0.027
positive regulation of intracellular transport	GO:0032388	70	0.027	Human
glycosyl compound catabolic process	GO:1901658	206	0.027
t cell anergy	GO:0002870	4	0.027
lymphocyte apoptotic process	GO:0070227	54	0.026
positive regulation of endothelial cell proliferation	GO:0001938	17	0.026	Mouse
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.026
cell fate specification	GO:0001708	72	0.026
protein localization to organelle	GO:0033365	185	0.026
inorganic cation transmembrane transport	GO:0098662	207	0.026
ensheathment of neurons	GO:0007272	76	0.026	Mouse
oxidation reduction process	GO:0055114	342	0.026
regulation of regulated secretory pathway	GO:1903305	20	0.026	Mouse
ribonucleoside metabolic process	GO:0009119	245	0.025
positive regulation of leukocyte differentiation	GO:1902107	86	0.025
acute inflammatory response to antigenic stimulus	GO:0002438	12	0.025	Mouse
negative regulation of macrophage apoptotic process	GO:2000110	3	0.025	Mouse
skin development	GO:0043588	220	0.025
neutrophil mediated killing of gram positive bacterium	GO:0070946	2	0.025
developmental maturation	GO:0021700	193	0.025
asymmetric stem cell division	GO:0098722	3	0.025
osteoclast differentiation	GO:0030316	62	0.025
purine nucleotide metabolic process	GO:0006163	302	0.025	Human
purine ribonucleoside metabolic process	GO:0046128	241	0.025
regulation of cell projection organization	GO:0031344	206	0.025
positive thymic t cell selection	GO:0045059	13	0.025
sphingolipid metabolic process	GO:0006665	45	0.025
nucleoside phosphate catabolic process	GO:1901292	222	0.025
female gamete generation	GO:0007292	74	0.025
methylation	GO:0032259	134	0.025
antigen processing and presentation of exogenous antigen	GO:0019884	26	0.025
negative regulation of protein phosphorylation	GO:0001933	126	0.025
epithelial cell proliferation	GO:0050673	174	0.025	Human Mouse
positive regulation of apoptotic process	GO:0043065	217	0.025	Human
filopodium assembly	GO:0046847	19	0.025
immune complex clearance	GO:0002434	2	0.024	Mouse
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.024
natural killer cell inhibitory signaling pathway	GO:0002769	2	0.024
purine ribonucleoside catabolic process	GO:0046130	205	0.024
negative regulation of phosphorus metabolic process	GO:0010563	184	0.024
positive regulation of programmed cell death	GO:0043068	218	0.024	Human
tolerance induction to self antigen	GO:0002513	4	0.024
dendritic spine maintenance	GO:0097062	4	0.024
positive regulation of bone remodeling	GO:0046852	13	0.024
cardiac muscle tissue development	GO:0048738	130	0.024
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.024	Mouse
negative regulation of protein serine threonine kinase activity	GO:0071901	49	0.024
mitotic cell cycle process	GO:1903047	159	0.024

Cxcr3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.029
disease of anatomical entity	DOID:7	0.027
musculoskeletal system disease	DOID:17	0.027

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