Mus musculus

35 known processes

Cxcr2

chemokine (C-X-C motif) receptor 2

(Aliases: Il8rb,Gpcr16,IL8RA,CD128,CDw128,mIL-8RH,IL-8rb,IL-8Rh,Cmkar2)

Cxcr2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of inflammatory responseGO:00507271470.912
Mouse
neutrophil chemotaxisGO:0030593360.819
Human Mouse Rat
cell chemotaxisGO:0060326810.758
Human Mouse Rat
inflammatory responseGO:00069542440.711
Mouse Rat
leukocyte chemotaxisGO:0030595690.685
Human Mouse Rat
neutrophil migrationGO:1990266370.675
Human Mouse Rat
granulocyte migrationGO:0097530430.662
Human Mouse Rat
chemotaxisGO:00069352470.609
Human Mouse Rat
cytokine mediated signaling pathwayGO:00192211150.607
myeloid leukocyte migrationGO:0097529570.570
Human Mouse Rat
regulation of neutrophil migrationGO:1902622140.569
Mouse Rat
inflammatory response to antigenic stimulusGO:0002437300.553
Mouse Rat
cellular response to cytokine stimulusGO:00713451890.552
myeloid leukocyte mediated immunityGO:0002444420.525
Mouse
positive regulation of monocyte chemotaxisGO:009002620.525
Mouse
monocyte extravasationGO:003569620.519
Mouse
immune effector processGO:00022523210.506
Mouse
leukocyte activation involved in immune responseGO:00023661260.496
Mouse
acute inflammatory responseGO:0002526410.461
Mouse Rat
cytokine metabolic processGO:0042107710.442
Mouse
positive regulation of defense responseGO:00313491240.437
Mouse
eosinophil activation involved in immune responseGO:000227810.418
Mouse
immune response regulating signaling pathwayGO:00027641250.414
Mouse
regulation of cell activationGO:00508652890.413
Mouse
regulation of cytokine biosynthetic processGO:0042035590.411
Mouse
regulation of lymphocyte activationGO:00512492400.407
Mouse
regulation of cytokine productionGO:00018172660.395
Mouse
t helper 17 cell chemotaxisGO:003570510.389
Mouse
regulation of monocyte extravasationGO:200043720.388
Mouse
regulation of immunological synapse formationGO:200052020.385
Mouse
granulocyte chemotaxisGO:0071621390.383
Human Mouse Rat
regulation of granulocyte chemotaxisGO:0071622170.377
Mouse Rat
regulation of chemokine productionGO:0032642300.376
immune response activating cell surface receptor signaling pathwayGO:0002429720.376
Mouse
myeloid leukocyte activationGO:0002274830.367
Human Mouse
symbiosis encompassing mutualism through parasitismGO:0044403830.352
regulation of vesicle mediated transportGO:00606271390.351
Mouse
cytokine productionGO:00018163190.347
Mouse
negative regulation of adaptive immune responseGO:0002820250.346
positive regulation of lymphocyte activationGO:00512511400.331
Mouse
regulation of multi organism processGO:00439001110.326
defense response to other organismGO:00985421970.304
defense response to gram positive bacteriumGO:0050830500.303
defense response to bacteriumGO:00427421190.300
regulation of neutrophil chemotaxisGO:0090022140.291
Mouse Rat
eosinophil degranulationGO:004330810.283
Mouse
negative regulation of immune system processGO:00026832090.282
Mouse Rat
positive regulation of neutrophil chemotaxisGO:0090023120.266
Mouse Rat
myeloid leukocyte differentiationGO:00025731190.264
regulation of vascular endothelial growth factor productionGO:0010574130.256
Mouse
response to molecule of bacterial originGO:00022371430.254
Mouse
immune response activating signal transductionGO:00027571160.254
Mouse
regulation of response to woundingGO:19030341890.252
Mouse
negative regulation of leukocyte mediated immunityGO:0002704290.252
Mouse
regulation of adaptive immune responseGO:0002819900.252
Mouse
ameboidal type cell migrationGO:00016671280.250
Mouse
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.250
Mouse
leukocyte differentiationGO:00025213420.246
Mouse
interaction with symbiontGO:0051702140.244
helper t cell chemotaxisGO:003570410.243
Mouse
interleukin 12 secretionGO:007261030.242
Mouse
divalent inorganic cation homeostasisGO:00725071380.241
Mouse Rat
action potentialGO:0001508780.237
positive regulation of dendritic cell chemotaxisGO:200051010.236
Mouse
regulation of antigen receptor mediated signaling pathwayGO:0050854290.233
Mouse
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.232
positive regulation of t cell costimulationGO:200052520.229
Mouse
keratinocyte migrationGO:005154630.226
positive regulation of cytokine productionGO:00018191740.225
Mouse
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formationGO:200052610.223
Mouse
myeloid cell activation involved in immune responseGO:0002275340.222
Mouse
positive regulation of t cell receptor signaling pathwayGO:005086240.221
Mouse
humoral immune responseGO:0006959570.219
Mouse
positive regulation of chemotaxisGO:0050921380.213
Mouse Rat
regulation of defense responseGO:00313472330.211
Mouse
negative regulation of secretionGO:0051048610.209
Mouse
interspecies interaction between organismsGO:0044419830.206
natural killer cell activationGO:0030101440.203
innate immune response in mucosaGO:000222730.203
regulation of myeloid leukocyte mediated immunityGO:0002886250.201
Mouse
cd8 positive alpha beta t cell extravasationGO:003569730.201
Mouse
negative regulation of secretion by cellGO:1903531540.201
Mouse
response to lipopolysaccharideGO:00324961280.198
Mouse
acute inflammatory response to antigenic stimulusGO:0002438120.197
Mouse Rat
killing of cells in other organism involved in symbiotic interactionGO:0051883130.197
axon ensheathmentGO:0008366760.196
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.192
Mouse
regulation of dendritic cell chemotaxisGO:200050810.192
Mouse
chemokine metabolic processGO:0050755100.191
regulation of leukocyte differentiationGO:19021051590.188
eosinophil activationGO:004330710.187
Mouse
negative regulation of cell proliferationGO:00082852960.187
eosinophil mediated immunityGO:000244710.181
Mouse
positive regulation of angiogenesisGO:0045766460.178
Mouse Rat
nitrogen compound transportGO:00717052710.178
protein secretionGO:00093061110.173
Mouse
monocarboxylic acid biosynthetic processGO:0072330610.171
regulation of cell motilityGO:20001452360.170
Mouse Rat
macrophage chemotaxisGO:0048246140.170
Mouse
myeloid cell apoptotic processGO:0033028220.169
Mouse Rat
negative regulation of cell activationGO:00508661110.167
Mouse
regulation of hypersensitivityGO:0002883100.167
Mouse
positive regulation of immunological synapse formationGO:200052210.165
Mouse
killing by host of symbiont cellsGO:0051873110.164
regulation of exocytosisGO:0017157610.163
Mouse
gliogenesisGO:00420631410.161
Mouse
negative regulation of chemokine productionGO:003268240.161
adaptive immune responseGO:00022501550.159
Mouse
macrophage activationGO:0042116270.159
Mouse
regulation of mast cell activationGO:0033003210.158
positive regulation of monocyte extravasationGO:200043910.157
Mouse
vascular endothelial growth factor productionGO:0010573130.150
Mouse
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.145
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.145
Mouse
cytokine biosynthetic processGO:0042089680.144
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.142
Mouse
exocytosisGO:00068871210.142
Mouse
calcium mediated signalingGO:0019722460.140
positive regulation of hematopoietic stem cell migrationGO:200047310.138
Mouse
activation of immune responseGO:00022531380.138
Mouse
positive regulation of chemokine secretionGO:009019740.138
positive regulation of behaviorGO:0048520400.138
Mouse Rat
g protein coupled receptor signaling pathwayGO:00071862430.137
lymphocyte mediated immunityGO:00024491390.136
activation of mapk activity involved in innate immune responseGO:003541920.135
cell activation involved in immune responseGO:00022631260.131
Mouse
regulation of cellular amine metabolic processGO:0033238200.129
production of molecular mediator of immune responseGO:00024401030.129
ensheathment of neuronsGO:0007272760.127
Mouse
hematopoietic stem cell migrationGO:003570110.126
Mouse
regulation of cell cycleGO:00517262810.125
neutrophil mediated immunityGO:0002446190.124
t cell activationGO:00421102890.123
Mouse
regulation of inflammatory response to antigenic stimulusGO:0002861210.122
Mouse
positive regulation of t cell extravasationGO:200040920.121
Mouse
chemokine productionGO:0032602340.121
negative regulation of immune effector processGO:0002698550.115
Mouse
membrane organizationGO:00610242450.112
Mouse
cell killingGO:0001906670.110
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.109
Mouse
regulation of protein localizationGO:00328802310.108
Mouse
cation homeostasisGO:00550802120.108
Mouse Rat
immune complex clearanceGO:000243420.107
Mouse
regulation of macrophage activationGO:0043030170.107
stem cell differentiationGO:00488632680.106
positive regulation of granulocyte chemotaxisGO:0071624120.105
Mouse Rat
lymphocyte proliferationGO:00466511640.105
Mouse
leukocyte mediated immunityGO:00024431740.105
Mouse
disruption by host of symbiont cellsGO:0051852110.104
lymphocyte differentiationGO:00300982420.103
Mouse
regulation of immunoglobulin mediated immune responseGO:0002889370.103
positive regulation of response to woundingGO:1903036660.103
Mouse
regulation of t cell costimulationGO:200052320.103
Mouse
positive regulation of inflammatory responseGO:0050729470.102
Mouse
intracellular protein transportGO:00068862040.102
cell adhesionGO:00071553290.100
positive regulation of chemokine productionGO:0032722220.100
blood vessel morphogenesisGO:00485142850.099
Mouse Rat
muscle tissue developmentGO:00605373080.099
peptidyl amino acid modificationGO:00181933360.098
interferon gamma productionGO:0032609670.098
Mouse
cytokine secretionGO:0050663720.097
Mouse
innate immune responseGO:00450871570.096
Mouse
alpha beta t cell activationGO:0046631910.096
Mouse
positive regulation of interferon gamma productionGO:0032729390.095
Mouse
myeloid cell differentiationGO:00300992330.095
Mouse
t cell extravasationGO:007268340.094
Mouse
antibacterial peptide productionGO:000277820.093
glycoprotein metabolic processGO:00091001160.091
Mouse
positive regulation of neutrophil migrationGO:1902624120.091
Mouse Rat
organic acid biosynthetic processGO:0016053860.090
cellular response to lipopolysaccharideGO:0071222770.090
axonogenesisGO:00074092740.088
Mouse
regulation of secretion by cellGO:19035302490.087
Mouse
epithelial tube morphogenesisGO:00605623030.086
Mouse Rat
hypersensitivityGO:0002524100.086
Mouse
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.086
Mouse
innate immune response activating signal transductionGO:0002758500.086
positive regulation of cell motilityGO:20001471160.086
Mouse Rat
leukocyte migrationGO:00509001240.086
Human Mouse Rat
positive regulation of nervous system developmentGO:00519622210.085
Mouse
regulation of cell migrationGO:00303342190.085
Mouse Rat
positive regulation of tumor necrosis factor biosynthetic processGO:004253580.084
Mouse
cellular amide metabolic processGO:0043603580.084
negative regulation of multi organism processGO:0043901680.083
negative regulation of phagocytosisGO:005076540.083
cellular extravasationGO:0045123170.083
Mouse
negative regulation of t cell mediated immunityGO:000271090.082
negative regulation of macrophage apoptotic processGO:200011030.081
Mouse
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.081
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.081
Mouse
positive regulation of acute inflammatory responseGO:0002675160.081
Mouse
dendritic cell chemotaxisGO:000240770.081
Mouse
regulation of interleukin 2 productionGO:0032663280.080
Mouse
negative regulation of exocytosisGO:0045920120.080
Mouse
modification of morphology or physiology of other organismGO:0035821180.080
angiogenesisGO:00015252010.080
Mouse Rat
digestive tract morphogenesisGO:00485461470.079
interleukin 18 mediated signaling pathwayGO:003565520.079
regulation of chemokine secretionGO:009019640.079
wound healingGO:00420601570.079
regulation of tumor necrosis factor biosynthetic processGO:0042534100.079
Mouse
t cell receptor signaling pathwayGO:0050852460.079
Mouse
leukocyte proliferationGO:00706611720.078
Mouse
regulation of tumor necrosis factor productionGO:0032680490.077
Mouse
chemokine secretionGO:009019550.077
regulation of hormone levelsGO:00108172110.077
positive regulation of mapk cascadeGO:00434101700.077
negative regulation of defense responseGO:0031348770.076
Mouse
regulation of t helper 1 type immune responseGO:0002825170.076
Mouse
regulation of b cell mediated immunityGO:0002712370.075
maintenance of locationGO:0051235890.075
Mouse
regulation of t cell differentiationGO:0045580830.075
cytosolic calcium ion transportGO:0060401480.073
Mouse
small molecule biosynthetic processGO:00442831320.073
microglial cell activationGO:000177430.073
Mouse
positive regulation vascular endothelial growth factor productionGO:0010575100.072
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.071
Mouse
regulation of mapk cascadeGO:00434082480.071
positive regulation of leukocyte differentiationGO:1902107860.071
positive regulation of protein modification processGO:00314012990.071
immunoglobulin productionGO:0002377730.071
neutrophil mediated killing of gram positive bacteriumGO:007094620.071
neuronal action potentialGO:0019228540.070
organonitrogen compound biosynthetic processGO:19015661920.069
regulation of brown fat cell proliferationGO:007034710.069
negative regulation of response to woundingGO:1903035770.068
interleukin 6 productionGO:0032635580.068
phagocytosisGO:0006909660.068
b cell differentiationGO:0030183780.068
gland developmentGO:00487323300.068
regulation of cellular ketone metabolic processGO:0010565660.067
lysosome localizationGO:0032418200.067
negative regulation of eosinophil degranulationGO:004331010.067
Mouse
regulation of monocyte chemotaxisGO:009002530.067
Mouse
defense response to virusGO:0051607680.067
regulation of innate immune responseGO:0045088910.066
Mouse
response to oxidative stressGO:00069791230.066
myelinationGO:0042552740.066
Mouse
negative regulation of molecular functionGO:00440922580.066
striated muscle tissue developmentGO:00147062930.066
regulation of establishment of protein localizationGO:00702011810.066
Mouse
regulation of regulated secretory pathwayGO:1903305200.065
Mouse
negative regulation of chemokine biosynthetic processGO:004507920.065
regulation of toll like receptor signaling pathwayGO:0034121200.064
regulation of humoral immune responseGO:0002920220.063
Mouse
cytoplasmic transportGO:00164822340.063
Mouse
positive regulation of acute inflammatory response to antigenic stimulusGO:000286670.063
Mouse
interleukin 11 mediated signaling pathwayGO:003815420.062
neural precursor cell proliferationGO:00613511210.062
Mouse
negative regulation of cellular component organizationGO:00511291940.061
regulation of hematopoietic stem cell migrationGO:200047110.061
Mouse
regulation of inositol trisphosphate biosynthetic processGO:003296030.060
positive regulation of phagocytosisGO:0050766260.060
regulation of epithelial cell proliferationGO:00506781410.060
Mouse
positive regulation of glial cell differentiationGO:0045687210.060
Mouse
regulation of type 2 immune responseGO:0002828180.059
Mouse
mature dendritic cell differentiationGO:009702930.059
Mouse
immune complex clearance by monocytes and macrophagesGO:000243620.059
Mouse
cytosolic calcium ion homeostasisGO:0051480700.058
Mouse Rat
response to peptideGO:19016521360.058
regulated secretory pathwayGO:0045055320.058
Mouse
regulation of secretionGO:00510462740.058
Mouse
mucosal immune responseGO:0002385130.058
cation transportGO:00068123990.058
Mouse
dendritic cell migrationGO:0036336120.057
Mouse
negative regulation of intracellular signal transductionGO:19025321670.057
negative regulation of signal transduction in absence of ligandGO:1901099160.057
Mouse
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.057
Mouse
regulation of acute inflammatory responseGO:0002673270.057
Mouse
b cell activationGO:00421131610.057
ossificationGO:00015032160.057
regulation of b cell activationGO:0050864810.057
viral processGO:0016032410.056
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.055
Mouse
regulation of angiogenesisGO:0045765810.055
Mouse Rat
activation of mapk activityGO:0000187590.054
protein targetingGO:00066051430.054
positive regulation of cell activationGO:00508671580.054
Mouse
positive regulation of alpha beta t cell proliferationGO:0046641120.053
Mouse
cellular response to organonitrogen compoundGO:00714171450.053
response to acid chemicalGO:00011011110.052
negative regulation of interleukin 5 productionGO:003271440.052
second messenger mediated signalingGO:0019932730.052
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.051
chemokine mediated signaling pathwayGO:0070098170.051
positive regulation of cellular amine metabolic processGO:003324050.051
cellular response to hormone stimulusGO:00328701500.051
tumor necrosis factor superfamily cytokine productionGO:0071706510.050
Mouse
neuron projection guidanceGO:00974851410.050
Mouse
detection of fungusGO:001604620.050
fatty acid derivative biosynthetic processGO:1901570150.050
negative regulation of regulated secretory pathwayGO:190330670.049
Mouse
regulation of eosinophil degranulationGO:004330910.049
Mouse
interleukin 33 mediated signaling pathwayGO:003817210.049
cell surface pattern recognition receptor signaling pathwayGO:000275220.049
positive regulation of cellular amino acid metabolic processGO:004576430.049
negative regulation of inflammatory responseGO:0050728610.048
lymphocyte activation involved in immune responseGO:0002285930.048
regulation of t cell extravasationGO:200040730.048
Mouse
positive regulation of lymphocyte mediated immunityGO:0002708620.048
osteoclast differentiationGO:0030316620.048
regulation of cellular amino acid metabolic processGO:000652150.047
reactive oxygen species metabolic processGO:0072593840.047
chromatin modificationGO:00165681870.047
cellular response to dna damage stimulusGO:00069742070.047
regulation of leukocyte proliferationGO:00706631210.047
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.047
Mouse
regulation of protein transportGO:00512231630.047
Mouse
cellular lipid metabolic processGO:00442553230.047
immune response regulating cell surface receptor signaling pathwayGO:0002768800.046
Mouse
positive regulation of inositol phosphate biosynthetic processGO:006073220.046
positive regulation of protein serine threonine kinase activityGO:00719021060.046
negative regulation of protein secretionGO:0050709200.045
nuclear importGO:0051170950.045
positive regulation of chemokine biosynthetic processGO:004508060.045
peptide metabolic processGO:0006518460.045
regulation of homeostatic processGO:00328441820.044
Mouse Rat
positive regulation of myeloid cell differentiationGO:0045639430.044
glycoprotein biosynthetic processGO:0009101890.044
Mouse
negative regulation of leukocyte degranulationGO:004330170.044
Mouse
regulation of chemokine biosynthetic processGO:004507380.044
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic processGO:004542520.044
cellular response to peptide hormone stimulusGO:0071375920.044
regulation of lymphocyte differentiationGO:00456191070.044
antigen processing and presentationGO:0019882470.043
Mouse
regulation of interleukin 6 productionGO:0032675550.043
regulation of leukocyte mediated immunityGO:00027031040.043
Mouse
negative regulation of cytokine productionGO:0001818840.043
positive regulation of cytokine biosynthetic processGO:0042108400.043
Mouse
positive regulation of lymphocyte proliferationGO:0050671700.043
Mouse
regulation of alpha beta t cell activationGO:0046634530.043
Mouse
protein localization to organelleGO:00333651850.043
regulation of intracellular transportGO:00323861590.042
negative regulation of myeloid leukocyte mediated immunityGO:000288770.042
Mouse
stem cell proliferationGO:00720891170.042
negative regulation of cellular protein metabolic processGO:00322692470.042
positive regulation of myeloid leukocyte differentiationGO:0002763260.041
negative regulation of hypersensitivityGO:000288430.041
oxidation reduction processGO:00551143420.041
mrna transcriptionGO:000929940.041
interleukin 12 productionGO:0032615320.041
Mouse
transmission of nerve impulseGO:0019226760.041
signal transduction in absence of ligandGO:0038034550.040
Mouse
small gtpase mediated signal transductionGO:0007264970.040
b cell mediated immunityGO:0019724710.040
brown fat cell proliferationGO:007034210.040
antimicrobial peptide biosynthetic processGO:000277720.039
positive regulation of epithelial cell proliferationGO:0050679680.039
Mouse
neutrophil differentiationGO:003022330.039
fc epsilon receptor signaling pathwayGO:003809530.039
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.039
regulation of lymphocyte proliferationGO:00506701170.038
Mouse
leukocyte degranulationGO:0043299270.038
Mouse
interleukin 27 mediated signaling pathwayGO:007010610.038
positive regulation of camp mediated signalingGO:004395030.038
regulation of mast cell degranulationGO:0043304160.038
regulation of gliogenesisGO:0014013500.038
Mouse
response to radiationGO:00093141650.038
positive regulation of t cell activationGO:00508701010.038
Mouse
negative regulation of protein metabolic processGO:00512482820.038
modification by host of symbiont morphology or physiologyGO:0051851120.037
blood coagulationGO:0007596760.037
regulation of membrane potentialGO:00423911920.037
positive regulation of calcium mediated signalingGO:0050850150.037
regulation of myeloid leukocyte differentiationGO:0002761580.037
disruption of cells of other organism involved in symbiotic interactionGO:0051818130.036
tumor necrosis factor productionGO:0032640500.036
Mouse
mast cell activation involved in immune responseGO:0002279200.036
regulation of map kinase activityGO:00434051200.036
negative regulation of lipopolysaccharide mediated signaling pathwayGO:003166530.036
positive regulation of oligodendrocyte differentiationGO:004871490.036
Mouse
mrna transcription from rna polymerase ii promoterGO:004278940.036
positive regulation of transferase activityGO:00513471670.036
positive regulation of immune effector processGO:00026991070.035
Mouse
germ cell developmentGO:00072811850.035
Mouse
morphogenesis of a branching epitheliumGO:00611381930.035
Mouse
reactive nitrogen species metabolic processGO:200105700.035
single organism cell adhesionGO:00986021560.035
mapk cascadeGO:00001652810.035
nuclear transportGO:00511691390.035
phospholipid metabolic processGO:0006644870.035
apoptotic signaling pathwayGO:00971903060.035
Mouse
cellular response to peptideGO:1901653920.035
carboxylic acid biosynthetic processGO:0046394860.035
regulation of myeloid cell differentiationGO:0045637960.035
regulation of osteoclast differentiationGO:0045670360.035
compound eye developmentGO:004874910.035
organ or tissue specific immune responseGO:0002251130.035
jnk cascadeGO:0007254720.035
regulation of cellular response to stressGO:00801351590.034
divalent inorganic cation transportGO:00725111780.034
Mouse
metanephros developmentGO:0001656790.034
Rat
positive regulation of membrane protein ectodomain proteolysisGO:005104430.034
cell recognitionGO:0008037830.034
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.034
Mouse
regulation of transferase activityGO:00513382630.034
mast cell mediated immunityGO:0002448200.033
sequestering of metal ionGO:0051238190.033
Mouse
antibacterial peptide biosynthetic processGO:000278020.033
killing of cells of other organismGO:0031640130.032
cellular calcium ion homeostasisGO:00068741190.032
Mouse Rat
neutrophil mediated killing of symbiont cellGO:007094380.032
regulation of kinase activityGO:00435492490.032
methylationGO:00322591340.032
regulation of toll like receptor 2 signaling pathwayGO:003413530.032
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200260.032
Human
antibacterial peptide secretionGO:000277910.032
branching morphogenesis of an epithelial tubeGO:00487541590.032
Mouse
interleukin 8 productionGO:003263740.032
antimicrobial peptide productionGO:000277520.032
cellular ion homeostasisGO:00068731650.032
Mouse Rat
positive regulation of protein kinase activityGO:00458601440.032
positive regulation of macrophage activationGO:0043032100.031
granzyme mediated apoptotic signaling pathwayGO:000862610.031
t helper 1 type immune responseGO:0042088250.031
Mouse
protein import into nucleusGO:0006606950.031
amide transportGO:00428861380.030
amine metabolic processGO:0009308450.030
regulation of interferon gamma productionGO:0032649570.030
Mouse
regulation of leukocyte degranulationGO:0043300200.030
Mouse
mast cell activationGO:0045576270.030
stimulatory c type lectin receptor signaling pathwayGO:000222320.030
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.030
posttranscriptional regulation of gene expressionGO:00106081550.030
cerebral cortex cell migrationGO:0021795440.030
Mouse
regulation of chromosome organizationGO:0033044830.030
lipid biosynthetic processGO:00086101790.030
regulation of acute inflammatory response to antigenic stimulusGO:0002864100.030
Mouse
regulation of phagocytosisGO:0050764330.030
negative regulation of t cell cytokine productionGO:000272510.030
stem cell developmentGO:00488642190.030
cell growthGO:00160491300.029
positive regulation of coagulationGO:0050820130.029
positive regulation of protein phosphorylationGO:00019342420.029
neutrophil mediated cytotoxicityGO:007094280.029
positive regulation of intracellular transportGO:0032388700.029
motor neuron axon guidanceGO:0008045260.029
Mouse
negative regulation of bone trabecula formationGO:190015510.029
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.029
activation of innate immune responseGO:0002218560.029
mucopolysaccharide metabolic processGO:1903510250.029
interleukin 2 productionGO:0032623330.029
Mouse
regulation of interleukin 12 productionGO:0032655300.029
Mouse
immunoglobulin mediated immune responseGO:0016064690.028
lymphocyte migrationGO:0072676260.028
Mouse
eosinophil migrationGO:007267730.028
t cell costimulationGO:0031295140.028
Mouse
negative regulation of vasculature developmentGO:1901343260.028
Mouse
interleukin 18 productionGO:003262140.028
regulation of stress activated mapk cascadeGO:0032872690.028
regulation of tissue remodelingGO:0034103380.028
regulation of protein secretionGO:0050708820.028
Mouse
positive regulation of innate immune responseGO:0045089800.028
microglial cell activation involved in immune responseGO:000228210.028
Mouse
regulation of granulocyte macrophage colony stimulating factor biosynthetic processGO:004542320.028
macrophage differentiationGO:0030225200.028
single organism nuclear importGO:1902593950.027
forebrain developmentGO:00309003020.027
Mouse
protein importGO:00170381010.027
positive regulation of exocytosisGO:0045921200.027
embryonic placenta developmentGO:0001892980.027
antibacterial humoral responseGO:001973180.027
cellular response to follicle stimulating hormone stimulusGO:007137210.026
skeletal muscle organ developmentGO:00605381630.026
ribonucleotide metabolic processGO:00092592910.026
positive regulation of map kinase activityGO:0043406840.026
regulation of vasculature developmentGO:1901342880.026
Mouse Rat
positive regulation of gliogenesisGO:0014015270.026
Mouse
t cell differentiation in thymusGO:0033077770.026
Mouse
sequestering of calcium ionGO:0051208180.026
Mouse
response to hyperoxiaGO:005509320.025
negative regulation of lymphocyte proliferationGO:0050672450.025
cellular response to gonadotropin stimulusGO:007137140.025
negative regulation of interferon gamma productionGO:0032689180.025
positive regulation of hypersensitivityGO:000288570.025
Mouse
negative regulation of neuron apoptotic processGO:0043524920.025
regulation of histone modificationGO:0031056560.025
protein kinase b signalingGO:0043491740.025
glial cell differentiationGO:00100011310.025
Mouse
response to peptide hormoneGO:00434341270.025
kidney developmentGO:00018222130.025
Rat
cellular defense responseGO:000696860.025
Human Mouse
multicellular organismal homeostasisGO:00488711640.024
cd4 positive alpha beta t cell activationGO:0035710450.024
positive regulation of humoral immune responseGO:0002922110.024
Mouse
cellular response to insulin stimulusGO:0032869780.024
negative regulation of lymphocyte activationGO:0051250910.024
cellular response to molecule of bacterial originGO:0071219830.024

Cxcr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.269
immune system diseaseDOID:291400.269
disease of metabolismDOID:001466700.138
cancerDOID:16200.102
organ system cancerDOID:005068600.102
disease of cellular proliferationDOID:1456600.102
blood coagulation diseaseDOID:124700.061
hematopoietic system diseaseDOID:7400.061
inherited blood coagulation diseaseDOID:221400.043
hemorrhagic diseaseDOID:221300.036