Mus musculus

17 known processes

Dub1a

deubiquitinating enzyme 1a

(Aliases: DUB-1A)

Dub1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amine metabolic processGO:0044106440.057
cellular ketone metabolic processGO:0042180840.053
cellular amino acid metabolic processGO:00065201030.049
regulation of cellular amine metabolic processGO:0033238200.047
regulation of cellular ketone metabolic processGO:0010565660.045
cytokine productionGO:00018163190.044
regulation of cellular amino acid metabolic processGO:000652150.040
g protein coupled receptor signaling pathwayGO:00071862430.038
transmembrane transportGO:00550854120.038
cell adhesionGO:00071553290.036
macromolecule catabolic processGO:00090572810.035
Mouse
regulation of cytokine productionGO:00018172660.034
protein modification by small protein conjugation or removalGO:00706472070.034
inflammatory responseGO:00069542440.033
immune effector processGO:00022523210.033
innate immune responseGO:00450871570.030
amine metabolic processGO:0009308450.030
protein modification by small protein conjugationGO:00324461870.029
leukocyte differentiationGO:00025213420.029
cellular macromolecule catabolic processGO:00442652060.029
Mouse
regulation of membrane potentialGO:00423911920.029
action potentialGO:0001508780.029
nitrogen compound transportGO:00717052710.028
positive regulation of cellular amine metabolic processGO:003324050.027
carbohydrate metabolic processGO:00059752300.026
regulation of defense responseGO:00313472330.026
protein ubiquitinationGO:00165671710.026
response to organonitrogen compoundGO:00102432460.026
positive regulation of protein modification processGO:00314012990.026
positive regulation of cellular amino acid metabolic processGO:004576430.025
regulation of cell cycleGO:00517262810.025
Mouse
cellular response to lipidGO:00713961450.025
cellular response to lipopolysaccharideGO:0071222770.025
reactive oxygen species metabolic processGO:0072593840.025
regulation of lymphocyte activationGO:00512492400.025
regulation of leukocyte differentiationGO:19021051590.025
neuronal action potentialGO:0019228540.025
defense response to other organismGO:00985421970.025
regulation of establishment of protein localizationGO:00702011810.024
transmission of nerve impulseGO:0019226760.024
ossificationGO:00015032160.024
protein catabolic processGO:00301632210.023
Mouse
response to lipopolysaccharideGO:00324961280.023
apoptotic signaling pathwayGO:00971903060.023
cellular response to amino acid stimulusGO:0071230290.023
response to molecule of bacterial originGO:00022371430.023
blood vessel morphogenesisGO:00485142850.023
response to acid chemicalGO:00011011110.023
small gtpase mediated signal transductionGO:0007264970.023
regulation of mapk cascadeGO:00434082480.023
fat cell differentiationGO:00454441600.023
camera type eye developmentGO:00430102660.023
sensory perceptionGO:00076002450.023
synaptic transmissionGO:00072683290.022
regulation of cell activationGO:00508652890.022
regulation of cellular catabolic processGO:00313292420.022
Mouse
monocarboxylic acid metabolic processGO:00327871910.022
oxidation reduction processGO:00551143420.022
mapk cascadeGO:00001652810.022
nucleobase containing small molecule metabolic processGO:00550863520.022
skeletal system developmentGO:00015013560.021
regulation of response to woundingGO:19030341890.021
regulation of hormone levelsGO:00108172110.021
nucleoside phosphate metabolic processGO:00067533380.021
regulation of transferase activityGO:00513382630.021
regulation of kinase activityGO:00435492490.020
heterocycle catabolic processGO:00467002800.020
nucleotide metabolic processGO:00091173320.020
peptidyl amino acid modificationGO:00181933360.020
organic cyclic compound catabolic processGO:19013612950.020
ear developmentGO:00435832000.020
cellular response to organonitrogen compoundGO:00714171450.020
cation homeostasisGO:00550802120.020
stem cell developmentGO:00488642190.020
cytoplasmic transportGO:00164822340.020
cation transportGO:00068123990.019
purine nucleotide metabolic processGO:00061633020.019
adaptive immune responseGO:00022501550.019
cellular response to cytokine stimulusGO:00713451890.019
spermatogenesisGO:00072832840.019
ribonucleotide metabolic processGO:00092592910.019
regulation of organelle organizationGO:00330432890.019
Mouse
organonitrogen compound biosynthetic processGO:19015661920.019
regulation of t cell activationGO:00508631700.019
gland developmentGO:00487323300.019
multicellular organismal signalingGO:0035637910.019
cellular response to biotic stimulusGO:0071216920.019
regulation of reactive oxygen species metabolic processGO:2000377400.019
regulation of cell migrationGO:00303342190.019
lymphocyte differentiationGO:00300982420.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
purine containing compound metabolic processGO:00725213110.019
negative regulation of cellular amine metabolic processGO:003323910.019
negative regulation of cellular component organizationGO:00511291940.019
Mouse
myeloid cell differentiationGO:00300992330.018
cellular chemical homeostasisGO:00550822150.018
protein maturationGO:00516041760.018
cellular nitrogen compound catabolic processGO:00442702800.018
lymphocyte mediated immunityGO:00024491390.018
dna metabolic processGO:00062593030.018
hematopoietic progenitor cell differentiationGO:00022441430.018
angiogenesisGO:00015252010.018
positive regulation of cell deathGO:00109422240.018
response to amino acidGO:0043200370.018
negative regulation of cellular amino acid metabolic processGO:004576300.018
cellular lipid metabolic processGO:00442553230.018
cellular response to molecule of bacterial originGO:0071219830.018
response to radiationGO:00093141650.018
fertilizationGO:00095661270.018
negative regulation of protein metabolic processGO:00512482820.018
Mouse
ribose phosphate metabolic processGO:00196932910.018
kidney developmentGO:00018222130.018
muscle tissue developmentGO:00605373080.018
carbohydrate homeostasisGO:00335001280.017
regulation of protein localizationGO:00328802310.017
cellular homeostasisGO:00197252400.017
multicellular organism growthGO:00352641610.017
engulfment of apoptotic cellGO:004365230.017
stem cell differentiationGO:00488632680.017
developmental maturationGO:00217001930.017
positive regulation of transferase activityGO:00513471670.017
negative regulation of intracellular signal transductionGO:19025321670.017
maintenance of locationGO:0051235890.017
leukocyte mediated immunityGO:00024431740.017
muscle cell differentiationGO:00426922610.017
regulation of protein kinase activityGO:00458592320.017
cellular response to acid chemicalGO:0071229680.017
t cell activationGO:00421102890.017
urogenital system developmentGO:00016552610.017
response to organic cyclic compoundGO:00140701980.017
ion transmembrane transportGO:00342203610.016
regulation of cell motilityGO:20001452360.016
male gamete generationGO:00482322850.016
proteasomal protein catabolic processGO:0010498980.016
Mouse
defense response to bacteriumGO:00427421190.016
positive regulation of mapk cascadeGO:00434101700.016
cation transmembrane transportGO:00986552660.016
glucose homeostasisGO:00425931280.016
anatomical structure homeostasisGO:00602491450.016
multicellular organismal homeostasisGO:00488711640.016
chemotaxisGO:00069352470.016
negative regulation of cell proliferationGO:00082852960.016
tissue remodelingGO:00487711020.016
regulation of cell adhesionGO:00301551540.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.016
extracellular matrix organizationGO:00301981470.016
skin developmentGO:00435882200.016
organonitrogen compound catabolic processGO:19015652640.016
endocytosisGO:00068971680.016
metal ion homeostasisGO:00550651890.016
heart morphogenesisGO:00030071780.016
positive regulation of protein phosphorylationGO:00019342420.015
negative regulation of cellular protein metabolic processGO:00322692470.015
Mouse
intracellular protein transportGO:00068862040.015
regulation of ion transportGO:00432692150.015
cellular protein catabolic processGO:00442571550.015
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.015
germ cell developmentGO:00072811850.015
renal system developmentGO:00720012250.015
myeloid leukocyte differentiationGO:00025731190.015
protein localization to organelleGO:00333651850.015
ras protein signal transductionGO:0007265770.015
negative regulation of molecular functionGO:00440922580.015
forebrain developmentGO:00309003020.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
exocytosisGO:00068871210.015
negative regulation of phosphate metabolic processGO:00459361840.015
wnt signaling pathwayGO:00160551880.015
organelle fissionGO:00482851700.015
cellular response to growth factor stimulusGO:00713631970.015
retina development in camera type eyeGO:00600411190.015
protein processingGO:00164851630.015
regulation of neuron differentiationGO:00456642810.015
adult behaviorGO:00305341350.015
negative regulation of phosphorylationGO:00423261660.015
tissue homeostasisGO:00018941150.014
positive regulation of nervous system developmentGO:00519622210.014
regulation of secretionGO:00510462740.014
cognitionGO:00508901490.014
regulation of homeostatic processGO:00328441820.014
axonogenesisGO:00074092740.014
positive regulation of programmed cell deathGO:00430682180.014
positive regulation of cell developmentGO:00107202370.014
regulation of hydrolase activityGO:00513362460.014
small molecule biosynthetic processGO:00442831320.014
organic hydroxy compound metabolic processGO:19016152030.014
posttranscriptional regulation of gene expressionGO:00106081550.014
cellular response to hormone stimulusGO:00328701500.014
negative regulation of cell cycleGO:00457861230.014
Mouse
modification dependent protein catabolic processGO:00199411330.014
Mouse
extracellular structure organizationGO:00430621480.014
single organism cell adhesionGO:00986021560.014
regulation of lymphocyte differentiationGO:00456191070.014
lipid localizationGO:00108761260.014
mitotic cell cycleGO:00002781950.014
Mouse
positive regulation of protein kinase activityGO:00458601440.014
cell substrate adhesionGO:00315891300.014
membrane organizationGO:00610242450.014
cellular response to dna damage stimulusGO:00069742070.014
regulation of inflammatory responseGO:00507271470.014
epithelial tube morphogenesisGO:00605623030.014
multi multicellular organism processGO:00447061090.014
purine nucleoside triphosphate metabolic processGO:00091442260.013
striated muscle tissue developmentGO:00147062930.013
ribonucleoside metabolic processGO:00091192450.013
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathwayGO:005148240.013
aromatic compound catabolic processGO:00194392860.013
rhythmic processGO:00485111740.013
nucleoside phosphate catabolic processGO:19012922220.013
b cell activationGO:00421131610.013
negative regulation of immune system processGO:00026832090.013
purine ribonucleotide metabolic processGO:00091502900.013
regulation of secretion by cellGO:19035302490.013
regulation of protein transportGO:00512231630.013
regulation of system processGO:00440572000.013
rho protein signal transductionGO:0007266320.013
microtubule based processGO:00070172360.013
anion transportGO:00068201770.013
blood circulationGO:00080151950.013
reactive nitrogen species metabolic processGO:200105700.013
positive regulation of apoptotic processGO:00430652170.013
regulation of leukocyte mediated immunityGO:00027031040.013
inorganic ion transmembrane transportGO:00986602340.013
nuclear divisionGO:00002801580.013
positive regulation of kinase activityGO:00336741550.013
response to extracellular stimulusGO:00099911270.013
purine nucleoside metabolic processGO:00422782410.013
positive regulation of cytokine productionGO:00018191740.013
digestive system developmentGO:00551232000.013
positive regulation of lymphocyte activationGO:00512511400.013
nucleocytoplasmic transportGO:00069131390.013
ubiquitin dependent protein catabolic processGO:00065111290.013
Mouse
positive regulation of cell activationGO:00508671580.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
Mouse
leukocyte migrationGO:00509001240.013
regulation of mitotic cell cycleGO:00073461260.013
Mouse
response to nutrient levelsGO:00316671090.013
carbohydrate derivative catabolic processGO:19011362310.013
oocyte axis specificationGO:000730920.013
lipid biosynthetic processGO:00086101790.013
cell divisionGO:00513011200.012
positive regulation of defense responseGO:00313491240.012
response to growth factorGO:00708481980.012
regulation of cell projection organizationGO:00313442060.012
regulation of ossificationGO:00302781120.012
regulation of cell cycle processGO:00105641600.012
Mouse
homeostasis of number of cellsGO:00488722100.012
regulation of nucleotide metabolic processGO:00061401690.012
regulation of body fluid levelsGO:00508781620.012
sensory organ morphogenesisGO:00905962420.012
response to inorganic substanceGO:0010035960.012
cell type specific apoptotic processGO:00972852680.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
epithelial cell developmentGO:00020641590.012
oocyte constructionGO:000730820.012
conditioned taste aversionGO:000166140.012
organelle localizationGO:00516401790.012
mitotic cell cycle processGO:19030471590.012
Mouse
rna processingGO:00063961050.012
glial cell differentiationGO:00100011310.012
ensheathment of neuronsGO:0007272760.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
cellular metal ion homeostasisGO:00068751510.012
regulation of serotonin secretionGO:001406230.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
myelinationGO:0042552740.012
regulation of erk1 and erk2 cascadeGO:0070372710.012
chromatin organizationGO:00063252060.012
regulation of protein catabolic processGO:00421761080.012
Mouse
regulation of feeding behaviorGO:006025930.012
limb developmentGO:00601731660.012
regulation of cellular component biogenesisGO:00440871810.012
negative regulation of phosphorus metabolic processGO:00105631840.012
cellular ion homeostasisGO:00068731650.011
purine ribonucleoside metabolic processGO:00461282410.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
lateral inhibitionGO:004633110.011
ribonucleotide catabolic processGO:00092612080.011
organophosphate catabolic processGO:00464342320.011
gliogenesisGO:00420631410.011
regulation of protein serine threonine kinase activityGO:00719001570.011
nucleoside triphosphate catabolic processGO:00091432050.011
modification dependent macromolecule catabolic processGO:00436321330.011
Mouse
placenta developmentGO:00018901400.011
amide transportGO:00428861380.011
positive regulation of immune effector processGO:00026991070.011
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
negative regulation of protein modification processGO:00314001630.011
nucleoside triphosphate metabolic processGO:00091412300.011
nuclear transportGO:00511691390.011
cytokine metabolic processGO:0042107710.011
leukocyte proliferationGO:00706611720.011
protein targetingGO:00066051430.011
peptide transportGO:00158331330.011
myeloid cell homeostasisGO:00022621140.011
cell maturationGO:00484691270.011
chromatin modificationGO:00165681870.011
defense response to virusGO:0051607680.011
production of molecular mediator of immune responseGO:00024401030.011
muscle system processGO:00030121410.011
activation of immune responseGO:00022531380.011
cellular carbohydrate metabolic processGO:00442621190.011
t cell differentiationGO:00302171740.011
regulation of multi organism processGO:00439001110.011
carboxylic acid biosynthetic processGO:0046394860.011
locomotory behaviorGO:00076261950.011
erk1 and erk2 cascadeGO:0070371770.011
positive regulation of cell motilityGO:20001471160.011
divalent inorganic cation homeostasisGO:00725071380.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
cell activation involved in immune responseGO:00022631260.011
peptidyl tyrosine phosphorylationGO:00181081430.011
glycosyl compound metabolic processGO:19016572460.011
t cell mediated immunityGO:0002456500.011
regulation of cellular response to stressGO:00801351590.011
glycoprotein metabolic processGO:00091001160.011
regulation of action potentialGO:009890040.011
purine ribonucleotide catabolic processGO:00091542080.011
sequestering of metal ionGO:0051238190.010
positive regulation of organelle organizationGO:00106381280.010
regulation of transmembrane transportGO:00347621280.010
methylationGO:00322591340.010
cytokine mediated signaling pathwayGO:00192211150.010
interferon gamma productionGO:0032609670.010
protein secretionGO:00093061110.010
cell killingGO:0001906670.010
morphogenesis of a branching epitheliumGO:00611381930.010
epidermis developmentGO:00085441870.010
hormone metabolic processGO:0042445860.010
positive regulation of apoptotic signaling pathwayGO:2001235950.010
respiratory system developmentGO:00605411900.010
organophosphate biosynthetic processGO:00904071220.010
response to light stimulusGO:00094161350.010
purine containing compound catabolic processGO:00725232130.010
axon ensheathmentGO:0008366760.010
regulation of cytoplasmic transportGO:19036491120.010
negative regulation of defense responseGO:0031348770.010
respiratory tube developmentGO:00303231670.010
appendage developmentGO:00487361660.010
positive regulation of vasoconstrictionGO:004590740.010
inorganic cation transmembrane transportGO:00986622070.010
carboxylic acid transportGO:00469421000.010
single organismal cell cell adhesionGO:00163371310.010
positive regulation of cellular catabolic processGO:00313311480.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.010
nucleoside metabolic processGO:00091162460.010
negative regulation of cell activationGO:00508661110.010
negative regulation of cytokine productionGO:0001818840.010
symbiosis encompassing mutualism through parasitismGO:0044403830.010
regulation of purine nucleotide metabolic processGO:19005421690.010
establishment of protein localization to organelleGO:00725941180.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.010
Mouse
sequestering of calcium ionGO:0051208180.010
purine nucleoside triphosphate catabolic processGO:00091462030.010
reactive oxygen species biosynthetic processGO:190340980.010

Dub1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.012
central nervous system diseaseDOID:33100.010