Mus musculus

218 known processes

Sod2

superoxide dismutase 2, mitochondrial

(Aliases: Sod-2,MGC6144,MnSOD)

Sod2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
generation of precursor metabolites and energyGO:00060911030.440
oxidation reduction processGO:00551143420.430
mitochondrion organizationGO:00070051340.411
purine ribonucleoside metabolic processGO:00461282410.282
nucleobase containing small molecule metabolic processGO:00550863520.225
intrinsic apoptotic signaling pathwayGO:00971931320.186
regulation of mitochondrial fissionGO:009014030.179
nucleotide metabolic processGO:00091173320.163
amine metabolic processGO:0009308450.147
cellular amine metabolic processGO:0044106440.141
energy derivation by oxidation of organic compoundsGO:0015980770.141
purine nucleoside metabolic processGO:00422782410.133
regulation of membrane potentialGO:00423911920.126
cellular respirationGO:0045333380.123
transmembrane transportGO:00550854120.121
nitrogen compound transportGO:00717052710.117
cellular amino acid metabolic processGO:00065201030.117
cellular ketone metabolic processGO:0042180840.115
cellular macromolecule catabolic processGO:00442652060.115
heterocycle catabolic processGO:00467002800.114
apoptotic signaling pathwayGO:00971903060.113
nucleoside phosphate metabolic processGO:00067533380.110
organic hydroxy compound metabolic processGO:19016152030.104
ribose phosphate metabolic processGO:00196932910.103
atp metabolic processGO:0046034750.103
regulation of cellular amine metabolic processGO:0033238200.102
nucleoside metabolic processGO:00091162460.101
monocarboxylic acid metabolic processGO:00327871910.100
glycosyl compound metabolic processGO:19016572460.099
response to oxygen levelsGO:0070482620.094
small molecule biosynthetic processGO:00442831320.093
pyruvate transportGO:000684820.092
organic acid biosynthetic processGO:0016053860.092
positive regulation of cell deathGO:00109422240.091
nucleoside monophosphate metabolic processGO:0009123850.091
organonitrogen compound biosynthetic processGO:19015661920.088
ion transmembrane transportGO:00342203610.088
ribonucleoside monophosphate metabolic processGO:0009161800.087
mitochondrial transportGO:0006839360.087
organic anion transportGO:00157111370.085
sulfur compound biosynthetic processGO:0044272370.085
purine nucleoside monophosphate metabolic processGO:0009126810.083
purine ribonucleoside triphosphate metabolic processGO:00092052200.082
lipid biosynthetic processGO:00086101790.081
sulfur compound metabolic processGO:00067901000.080
purine containing compound metabolic processGO:00725213110.079
regulation of cellular catabolic processGO:00313292420.079
Fly
purine ribonucleotide metabolic processGO:00091502900.078
protein processingGO:00164851630.076
cellular lipid metabolic processGO:00442553230.075
ribonucleoside triphosphate metabolic processGO:00091992200.074
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.073
Human
regulation of apoptotic signaling pathwayGO:20012331970.071
Human
nucleoside triphosphate metabolic processGO:00091412300.068
reactive oxygen species metabolic processGO:0072593840.065
positive regulation of programmed cell deathGO:00430682180.065
cation transmembrane transportGO:00986552660.064
ribonucleotide metabolic processGO:00092592910.063
purine ribonucleoside monophosphate metabolic processGO:0009167800.061
spermatogenesisGO:00072832840.061
cellular nitrogen compound catabolic processGO:00442702800.060
neuron apoptotic processGO:00514021420.060
Human
neuron deathGO:00709971540.059
Human
cell type specific apoptotic processGO:00972852680.059
Human
peptidyl amino acid modificationGO:00181933360.057
purine nucleoside triphosphate metabolic processGO:00091442260.057
regulation of cellular ketone metabolic processGO:0010565660.056
cation transportGO:00068123990.055
protein localization to organelleGO:00333651850.054
protein localization to mitochondrionGO:0070585150.053
cytoplasmic transportGO:00164822340.053
regulation of endopeptidase activityGO:0052548890.052
positive regulation of apoptotic processGO:00430652170.051
organic cyclic compound catabolic processGO:19013612950.049
cristae formationGO:004240730.049
cellular response to lipidGO:00713961450.048
positive regulation of cellular amine metabolic processGO:003324050.048
glycerolipid biosynthetic processGO:0045017500.048
striated muscle tissue developmentGO:00147062930.048
response to molecule of bacterial originGO:00022371430.047
ribonucleoside metabolic processGO:00091192450.046
positive regulation of cellular amino acid metabolic processGO:004576430.044
negative regulation of phosphorus metabolic processGO:00105631840.044
carboxylic acid biosynthetic processGO:0046394860.043
regulation of cellular amino acid metabolic processGO:000652150.043
aldehyde catabolic processGO:004618540.043
regulation of hydrolase activityGO:00513362460.043
carboxylic acid transportGO:00469421000.042
anion transportGO:00068201770.042
regulation of neuron deathGO:19012141340.040
Human
male gamete generationGO:00482322850.040
positive regulation of proteolysisGO:0045862850.040
intracellular protein transportGO:00068862040.039
positive regulation of hydrolase activityGO:00513451480.039
inflammatory responseGO:00069542440.039
regulation of kinase activityGO:00435492490.039
oxidative phosphorylationGO:0006119140.038
negative regulation of cellular amine metabolic processGO:003323910.038
response to organonitrogen compoundGO:00102432460.038
response to nutrient levelsGO:00316671090.037
regulation of proteolysisGO:00301621640.037
acetyl coa biosynthetic process from pyruvateGO:000608630.037
cellular modified amino acid metabolic processGO:0006575630.037
response to lipopolysaccharideGO:00324961280.037
regulation of cysteine type endopeptidase activityGO:2000116650.037
inorganic cation transmembrane transportGO:00986622070.036
regulation of organelle organizationGO:00330432890.036
cellular homeostasisGO:00197252400.035
macromolecule catabolic processGO:00090572810.035
aromatic compound catabolic processGO:00194392860.035
organic acid transportGO:00158491010.035
mitochondrial pyruvate transportGO:000685020.035
glycerophospholipid biosynthetic processGO:0046474320.034
response to inorganic substanceGO:0010035960.034
activation of cysteine type endopeptidase activityGO:0097202270.034
positive regulation of protein modification processGO:00314012990.033
negative regulation of intracellular signal transductionGO:19025321670.033
Human
monocarboxylic acid biosynthetic processGO:0072330610.033
cellular response to cytokine stimulusGO:00713451890.032
nuclear transportGO:00511691390.032
alcohol metabolic processGO:00060661160.032
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.032
purine nucleotide metabolic processGO:00061633020.032
coenzyme metabolic processGO:0006732520.032
regulation of phosphatidylcholine biosynthetic processGO:200124520.032
purine nucleoside catabolic processGO:00061522050.031
dna metabolic processGO:00062593030.031
coenzyme biosynthetic processGO:0009108230.031
negative regulation of cell proliferationGO:00082852960.031
positive regulation of protein phosphorylationGO:00019342420.030
regulation of protein kinase activityGO:00458592320.030
negative regulation of protein metabolic processGO:00512482820.030
homeostasis of number of cellsGO:00488722100.029
phagocytosisGO:0006909660.029
epithelial cell proliferationGO:00506731740.029
regulation of cytokine productionGO:00018172660.028
regulation of hormone levelsGO:00108172110.028
negative regulation of phosphorylationGO:00423261660.028
regulation of cell activationGO:00508652890.028
regulation of defense responseGO:00313472330.028
cofactor metabolic processGO:0051186800.028
regulation of protein transportGO:00512231630.028
organophosphate catabolic processGO:00464342320.027
regulation of neuron apoptotic processGO:00435231220.027
Human
myeloid cell differentiationGO:00300992330.027
purine nucleoside triphosphate catabolic processGO:00091462030.027
dna catabolic process endonucleolyticGO:0000737150.027
urogenital system developmentGO:00016552610.027
protein maturationGO:00516041760.027
developmental maturationGO:00217001930.027
epithelial tube morphogenesisGO:00605623030.026
inorganic ion transmembrane transportGO:00986602340.026
apoptotic nuclear changesGO:003026290.026
response to decreased oxygen levelsGO:0036293590.026
purine ribonucleotide catabolic processGO:00091542080.026
response to metal ionGO:0010038470.026
Zebrafish
mitochondrial electron transport nadh to ubiquinoneGO:000612040.026
cellular chemical homeostasisGO:00550822150.026
protein targetingGO:00066051430.026
regulation of intracellular transportGO:00323861590.025
regulation of peptidase activityGO:0052547960.025
monosaccharide metabolic processGO:00059961060.025
sensory perceptionGO:00076002450.025
negative regulation of phosphate metabolic processGO:00459361840.025
t cell activationGO:00421102890.025
small molecule catabolic processGO:0044282710.025
mapk cascadeGO:00001652810.025
glucose metabolic processGO:0006006920.024
multicellular organism growthGO:00352641610.024
immune effector processGO:00022523210.024
membrane organizationGO:00610242450.024
cellular response to hormone stimulusGO:00328701500.024
leukocyte differentiationGO:00025213420.024
regulation of establishment of protein localizationGO:00702011810.024
cofactor biosynthetic processGO:0051188410.024
spermatid differentiationGO:00485151150.024
gland developmentGO:00487323300.024
muscle tissue developmentGO:00605373080.024
carbohydrate metabolic processGO:00059752300.023
regulation of secretion by cellGO:19035302490.023
metal ion homeostasisGO:00550651890.023
regulation of lipid metabolic processGO:00192161180.023
extrinsic apoptotic signaling pathwayGO:00971911260.023
divalent metal ion transportGO:00708381720.023
response to hypoxiaGO:0001666580.023
innate immune responseGO:00450871570.022
purine nucleotide catabolic processGO:00061952110.022
negative regulation of molecular functionGO:00440922580.022
apoptotic mitochondrial changesGO:0008637480.022
spermatid developmentGO:00072861080.022
regulation of transferase activityGO:00513382630.022
response to extracellular stimulusGO:00099911270.022
peptide metabolic processGO:0006518460.021
regulation of intracellular protein transportGO:0033157820.021
glucose homeostasisGO:00425931280.021
protein hydroxylationGO:001812640.021
amide transportGO:00428861380.021
organophosphate biosynthetic processGO:00904071220.021
endocytosisGO:00068971680.021
establishment of protein localization to organelleGO:00725941180.021
ribonucleoside catabolic processGO:00424542060.021
mitochondrial membrane organizationGO:0007006260.021
negative regulation of neuron apoptotic processGO:0043524920.021
Human
monocarboxylic acid transportGO:0015718440.021
atp synthesis coupled electron transportGO:004277380.021
acetyl coa biosynthetic processGO:000608550.020
regulation of cytoplasmic transportGO:19036491120.020
negative regulation of apoptotic signaling pathwayGO:20012341040.020
Human
regulation of lymphocyte activationGO:00512492400.020
regulation of secretionGO:00510462740.020
tissue homeostasisGO:00018941150.020
lymphocyte proliferationGO:00466511640.020
lymphocyte differentiationGO:00300982420.020
t cell differentiationGO:00302171740.020
nucleocytoplasmic transportGO:00069131390.020
muscle cell differentiationGO:00426922610.020
negative regulation of cellular component organizationGO:00511291940.020
positive regulation of endopeptidase activityGO:0010950430.020
response to reactive oxygen speciesGO:0000302560.020
protein importGO:00170381010.020
negative regulation of cellular protein metabolic processGO:00322692470.019
cellular protein complex assemblyGO:00436231160.019
regulation of phospholipid biosynthetic processGO:007107130.019
regulation of leukocyte differentiationGO:19021051590.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.019
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.019
Human
response to oxidative stressGO:00069791230.019
protein ubiquitinationGO:00165671710.019
lateral inhibitionGO:004633110.019
organonitrogen compound catabolic processGO:19015652640.019
regulation of response to woundingGO:19030341890.019
glycerolipid metabolic processGO:00464861220.019
zymogen activationGO:0031638410.019
neural tube formationGO:00018411080.019
locomotory behaviorGO:00076261950.019
regulation of ion transportGO:00432692150.019
cytokine productionGO:00018163190.018
cellular amide metabolic processGO:0043603580.018
transmission of nerve impulseGO:0019226760.018
positive regulation of protein kinase activityGO:00458601440.018
regulation of protein serine threonine kinase activityGO:00719001570.018
dna catabolic processGO:0006308190.018
positive regulation of cysteine type endopeptidase activityGO:2001056390.018
purine containing compound catabolic processGO:00725232130.018
ossificationGO:00015032160.018
protein catabolic processGO:00301632210.018
protein refoldingGO:004202610.018
muscle fiber developmentGO:0048747760.018
carbohydrate homeostasisGO:00335001280.018
organic hydroxy compound transportGO:0015850930.018
cellular response to oxidative stressGO:0034599760.018
camera type eye developmentGO:00430102660.018
renal system developmentGO:00720012250.018
positive regulation of kinase activityGO:00336741550.018
cellular ion homeostasisGO:00068731650.018
divalent inorganic cation transportGO:00725111780.017
skeletal system developmentGO:00015013560.017
adult behaviorGO:00305341350.017
action potentialGO:0001508780.017
nucleotide catabolic processGO:00091662170.017
regulation of protein localizationGO:00328802310.017
regulation of protein targetingGO:1903533610.017
heart morphogenesisGO:00030071780.017
Fly
regulation of blood pressureGO:0008217930.017
cellular metal ion homeostasisGO:00068751510.017
b cell activationGO:00421131610.017
purine nucleotide biosynthetic processGO:0006164650.017
maintenance of locationGO:0051235890.017
synaptic transmissionGO:00072683290.016
positive regulation of apoptotic signaling pathwayGO:2001235950.016
carbohydrate derivative biosynthetic processGO:19011371830.016
cellular response to organonitrogen compoundGO:00714171450.016
alpha amino acid metabolic processGO:1901605590.016
peptide secretionGO:00027901140.016
ribonucleotide catabolic processGO:00092612080.016
glycosyl compound catabolic processGO:19016582060.016
negative regulation of alcohol biosynthetic processGO:190293140.016
fatty acid metabolic processGO:00066311210.016
sequestering of metal ionGO:0051238190.016
acyl coa biosynthetic processGO:007161670.016
positive regulation of transferase activityGO:00513471670.016
fatty acid biosynthetic processGO:0006633410.016
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.016
g protein coupled receptor signaling pathwayGO:00071862430.015
regulation of protein localization to nucleusGO:1900180600.015
regulation of map kinase activityGO:00434051200.015
leukocyte mediated immunityGO:00024431740.015
positive regulation of protein serine threonine kinase activityGO:00719021060.015
purine ribonucleoside catabolic processGO:00461302050.015
removal of superoxide radicalsGO:0019430120.015
divalent inorganic cation homeostasisGO:00725071380.015
cellular response to lipopolysaccharideGO:0071222770.015
myeloid leukocyte differentiationGO:00025731190.015
regulation of removal of superoxide radicalsGO:200012140.015
phosphatidylethanolamine metabolic processGO:004633720.015
positive regulation of cell developmentGO:00107202370.015
multicellular organismal homeostasisGO:00488711640.015
kidney developmentGO:00018222130.015
positive regulation of peptidase activityGO:0010952490.015
digestive system developmentGO:00551232000.015
positive regulation of reactive oxygen species metabolic processGO:2000379110.015
myeloid cell homeostasisGO:00022621140.015
regulation of cellular component biogenesisGO:00440871810.015
phospholipid biosynthetic processGO:0008654360.015
morphogenesis of embryonic epitheliumGO:00163311590.015
regulation of nucleocytoplasmic transportGO:0046822730.014
negative regulation of protein modification processGO:00314001630.014
nucleoside triphosphate catabolic processGO:00091432050.014
stem cell differentiationGO:00488632680.014
negative regulation of protein phosphorylationGO:00019331260.014
regulation of neuron differentiationGO:00456642810.014
neural tube developmentGO:00219151600.014
cellular response to molecule of bacterial originGO:0071219830.014
cellular response to biotic stimulusGO:0071216920.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
regulation of homeostatic processGO:00328441820.014
multicellular organismal signalingGO:0035637910.014
epidermis developmentGO:00085441870.014
sensory organ morphogenesisGO:00905962420.014
response to radiationGO:00093141650.014
epithelial cell developmentGO:00020641590.014
nucleoside phosphate catabolic processGO:19012922220.014
germ cell developmentGO:00072811850.014
nucleoside catabolic processGO:00091642060.014
regulation of vesicle mediated transportGO:00606271390.014
nuclear importGO:0051170950.014
nonribosomal peptide biosynthetic processGO:001918450.014
digestive tract morphogenesisGO:00485461470.014
cell agingGO:0007569350.013
hormone secretionGO:00468791280.013
autophagyGO:0006914450.013
Fly
substantia nigra developmentGO:002176220.013
negative regulation of kinase activityGO:0033673810.013
glycerophospholipid metabolic processGO:0006650710.013
response to steroid hormoneGO:0048545560.013
protein oxidationGO:001815820.013
cellular biogenic amine metabolic processGO:0006576280.013
lipid localizationGO:00108761260.013
defense response to other organismGO:00985421970.013
pyridine nucleotide biosynthetic processGO:001936340.013
synapse organizationGO:00508081250.013
sequestering of calcium ionGO:0051208180.013
regulation of system processGO:00440572000.013
thioester metabolic processGO:0035383190.013
negative regulation of organelle organizationGO:0010639900.013
negative regulation of transferase activityGO:0051348850.013
ribonucleotide biosynthetic processGO:0009260590.013
response to organic cyclic compoundGO:00140701980.013
peptide transportGO:00158331330.013
circulatory system processGO:00030131970.013
skin developmentGO:00435882200.013
positive regulation of cytokine productionGO:00018191740.013
negative regulation of immune system processGO:00026832090.013
interleukin 8 productionGO:003263740.013
regulation of transmembrane transportGO:00347621280.013
skeletal system morphogenesisGO:00487052030.013
regulation of microtubule based processGO:0032886520.012
negative regulation of growthGO:0045926990.012
carbohydrate derivative catabolic processGO:19011362310.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
negative regulation of neuron deathGO:1901215980.012
Human
connective tissue developmentGO:00614481790.012
regulation of t cell activationGO:00508631700.012
cellular response to extracellular stimulusGO:0031668810.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
positive regulation of response to woundingGO:1903036660.012
regulation of inflammatory responseGO:00507271470.012
triglyceride metabolic processGO:0006641510.012
regulation of lymphocyte differentiationGO:00456191070.012
mitochondrial atp synthesis coupled electron transportGO:004277580.012
rhythmic processGO:00485111740.012
cation homeostasisGO:00550802120.012
immune response activating signal transductionGO:00027571160.012
canonical wnt signaling pathwayGO:00600701300.012
activation of immune responseGO:00022531380.012
organelle fissionGO:00482851700.012
organic hydroxy compound biosynthetic processGO:1901617770.012
wound healingGO:00420601570.012
regulation of ion transmembrane transportGO:00347651190.012
regulation of multi organism processGO:00439001110.012
regulation of cellular response to stressGO:00801351590.012
Human
cellular aldehyde metabolic processGO:0006081120.012
adult locomotory behaviorGO:0008344910.012
nucleoside monophosphate catabolic processGO:0009125590.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
regulation of transporter activityGO:0032409570.011
translationGO:0006412930.011
leukocyte proliferationGO:00706611720.011
positive regulation of cell activationGO:00508671580.011
t cell proliferationGO:00420981200.011
immune response regulating signaling pathwayGO:00027641250.011
regulation of metal ion transportGO:00109591060.011
positive regulation of lymphocyte activationGO:00512511400.011
cellular response to oxygen levelsGO:0071453200.011
nucleic acid phosphodiester bond hydrolysisGO:0090305490.011
blood vessel morphogenesisGO:00485142850.011
calcium ion transportGO:00068161590.011
peptidyl tyrosine phosphorylationGO:00181081430.011
nucleoside phosphate biosynthetic processGO:1901293790.011
regulation of mitochondrion organizationGO:0010821270.011
reflexGO:0060004220.011
calcium ion homeostasisGO:00550741270.011
regulation of mitochondrial membrane potentialGO:0051881170.011
inner mitochondrial membrane organizationGO:000700750.011
negative regulation of t cell activationGO:0050868650.011
tube formationGO:00351481400.011
norepinephrine secretionGO:004824320.011
epithelial tube formationGO:00721751300.011
cofactor transportGO:005118140.011
cellular calcium ion homeostasisGO:00068741190.011
acylglycerol metabolic processGO:0006639550.011
selenium compound metabolic processGO:000188730.011
response to oxygen radicalGO:0000305160.011
anion transmembrane transportGO:0098656710.011
forebrain developmentGO:00309003020.011
cytokine mediated signaling pathwayGO:00192211150.011
acyl coa metabolic processGO:0006637190.011
protein localization to nucleusGO:00345041210.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
regulation of peptide transportGO:0090087910.011
serine family amino acid metabolic processGO:000906970.011
regulation of purine nucleotide metabolic processGO:19005421690.011
positive regulation of cellular catabolic processGO:00313311480.011
multi multicellular organism processGO:00447061090.011
erythrocyte differentiationGO:0030218880.011
regulation of epithelial cell proliferationGO:00506781410.011
neural precursor cell proliferationGO:00613511210.010
phospholipid metabolic processGO:0006644870.010
second messenger mediated signalingGO:0019932730.010
blood circulationGO:00080151950.010
peptidyl serine phosphorylationGO:0018105740.010
engulfment of apoptotic cellGO:004365230.010
sperm motilityGO:0030317470.010
citrate metabolic processGO:000610130.010
response to acid chemicalGO:00011011110.010
hydrogen peroxide metabolic processGO:0042743160.010
cell adhesionGO:00071553290.010
neuronal action potentialGO:0019228540.010
protein foldingGO:0006457280.010
positive regulation of organelle organizationGO:00106381280.010
regulation of mapk cascadeGO:00434082480.010
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.010
hormone metabolic processGO:0042445860.010
peptide hormone secretionGO:00300721090.010

Sod2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.126
inherited metabolic disorderDOID:65500.094
disease of cellular proliferationDOID:1456600.035
nervous system diseaseDOID:86300.032
disease of anatomical entityDOID:700.032
immune system diseaseDOID:291400.031
cancerDOID:16200.026
hematopoietic system diseaseDOID:7400.025
central nervous system diseaseDOID:33100.024
blood coagulation diseaseDOID:124700.023
organ system cancerDOID:005068600.019
hemorrhagic diseaseDOID:221300.013
blood platelet diseaseDOID:221800.013
neurodegenerative diseaseDOID:128900.011