Mus musculus

263 known processes

Myd88

myeloid differentiation primary response gene 88

Myd88 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to molecule of bacterial originGO:0071219831.000
nucleotide binding oligomerization domain containing signaling pathwayGO:007042361.000
activation of innate immune responseGO:0002218561.000
pattern recognition receptor signaling pathwayGO:0002221471.000
toll like receptor signaling pathwayGO:0002224381.000
regulation of interleukin 6 productionGO:0032675551.000
immune response regulating signaling pathwayGO:00027641251.000
positive regulation of innate immune responseGO:0045089801.000
immune response activating signal transductionGO:00027571161.000
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753101.000
regulation of innate immune responseGO:0045088911.000
response to interleukin 12GO:007067121.000
interleukin 18 mediated signaling pathwayGO:003565521.000
i kappab kinase nf kappab signalingGO:0007249851.000
lipopolysaccharide mediated signaling pathwayGO:0031663251.000
innate immune response activating signal transductionGO:0002758501.000
interferon beta biosynthetic processGO:004535041.000
response to interleukin 1GO:0070555111.000
Human
cytokine mediated signaling pathwayGO:00192211151.000
Rat
positive regulation of chemokine productionGO:0032722221.000
cellular response to lipopolysaccharideGO:0071222770.999
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.999
defense response to other organismGO:00985421970.999
cytokine productionGO:00018163190.999
negative regulation of interleukin 6 productionGO:0032715170.999
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.999
cellular response to biotic stimulusGO:0071216920.999
detection of molecule of bacterial originGO:003249020.999
regulation of interferon beta biosynthetic processGO:004535740.999
cellular response to interleukin 18GO:007135130.999
regulation of cytokine biosynthetic processGO:0042035590.999
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.998
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.998
activation of immune responseGO:00022531380.998
cellular response to peptidoglycanGO:007122440.998
toll like receptor 4 signaling pathwayGO:003414290.998
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.998
type i interferon productionGO:0032606290.998
positive regulation of nf kappab transcription factor activityGO:0051092300.997
chemokine productionGO:0032602340.997
cytokine biosynthetic processGO:0042089680.997
response to defense related nitric oxide production by other organism involved in symbiotic interactionGO:005255120.997
regulation of chemokine productionGO:0032642300.997
positive regulation of interferon beta biosynthetic processGO:004535930.996
response to peptidoglycanGO:003249490.996
positive regulation of cytokine biosynthetic processGO:0042108400.996
response to molecule of bacterial originGO:00022371430.996
regulation of macrophage cytokine productionGO:001093580.995
regulation of cytokine productionGO:00018172660.995
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.995
interleukin 8 productionGO:003263740.994
interleukin 1 mediated signaling pathwayGO:007049840.994
regulation of cell activationGO:00508652890.994
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.993
macrophage cytokine productionGO:001093490.992
positive regulation of type i interferon productionGO:0032481140.992
positive regulation of defense responseGO:00313491240.991
positive regulation of chemokine biosynthetic processGO:004508060.990
tumor necrosis factor superfamily cytokine productionGO:0071706510.988
positive regulation by symbiont of defense related host nitric oxide productionGO:005234710.987
positive regulation of interferon alpha productionGO:003272740.987
modulation by symbiont of defense related host nitric oxide productionGO:005216310.986
positive regulation of reactive oxygen species biosynthetic processGO:190342820.986
regulation of toll like receptor signaling pathwayGO:0034121200.986
regulation of leukocyte proliferationGO:00706631210.986
cellular response to cytokine stimulusGO:00713451890.985
Rat
cellular response to lipidGO:00713961450.985
b cell activationGO:00421131610.983
positive regulation of lymphocyte proliferationGO:0050671700.982
regulation of tumor necrosis factor productionGO:0032680490.982
regulation of defense responseGO:00313472330.982
interleukin 6 productionGO:0032635580.982
cytokine metabolic processGO:0042107710.981
response to lipopolysaccharideGO:00324961280.980
positive regulation of tumor necrosis factor productionGO:0032760300.980
positive regulation of interleukin 18 productionGO:003274120.980
negative regulation of cytokine productionGO:0001818840.980
regulation of cytokine production involved in immune responseGO:0002718260.980
immune effector processGO:00022523210.980
response to molecule of fungal originGO:000223840.980
positive regulation of cell activationGO:00508671580.979
innate immune responseGO:00450871570.978
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.975
positive regulation of reactive oxygen species metabolic processGO:2000379110.974
positive regulation of jnk cascadeGO:0046330460.974
positive regulation of interferon beta productionGO:003272880.972
negative regulation of immune system processGO:00026832090.972
interferon beta productionGO:0032608160.970
response to lipoteichoic acidGO:007039160.969
immune response regulating cell surface receptor signaling pathwayGO:0002768800.968
positive regulation of cytokine productionGO:00018191740.968
response to bacterial lipoproteinGO:003249340.967
production of molecular mediator of immune responseGO:00024401030.966
Fly
lymphocyte homeostasisGO:0002260640.962
response to dsrnaGO:0043331300.959
positive regulation of b cell activationGO:0050871490.959
regulation of jnk cascadeGO:0046328620.959
chemokine biosynthetic processGO:004203380.958
ripoptosome assembly involved in necroptotic processGO:190102660.958
toll like receptor 2 signaling pathwayGO:003413460.956
positive regulation of interleukin 6 productionGO:0032755370.952
regulation of lymphocyte proliferationGO:00506701170.950
chemokine metabolic processGO:0050755100.950
jnk cascadeGO:0007254720.949
tumor necrosis factor mediated signaling pathwayGO:0033209130.947
interleukin 17 productionGO:0032620110.946
negative regulation of toll like receptor signaling pathwayGO:0034122140.944
negative regulation of defense responseGO:0031348770.941
response to organonitrogen compoundGO:00102432460.940
positive regulation of leukocyte proliferationGO:0070665730.938
natural killer cell activationGO:0030101440.937
regulation of b cell proliferationGO:0030888390.936
cellular response to lipoteichoic acidGO:007122360.932
antibacterial peptide productionGO:000277820.928
negative regulation of tumor necrosis factor superfamily cytokine productionGO:1903556170.927
regulation of necroptotic processGO:0060544100.913
adaptive immune responseGO:00022501550.911
regulation of production of molecular mediator of immune responseGO:0002700650.911
Fly
positive regulation by symbiont of host immune responseGO:005255610.908
positive regulation of interleukin 8 productionGO:003275720.908
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.907
modulation by organism of immune response of other organism involved in symbiotic interactionGO:005255210.907
regulation of type i interferon productionGO:0032479220.899
regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043230.896
activation of nf kappab inducing kinase activityGO:000725040.895
modulation by symbiont of host defense responseGO:005203110.894
type i interferon signaling pathwayGO:0060337100.892
defense response to virusGO:0051607680.892
regulation of cellular amino acid metabolic processGO:000652150.889
positive regulation of interferon gamma productionGO:0032729390.886
nik nf kappab signalingGO:0038061140.882
regulation of reactive oxygen species biosynthetic processGO:190342620.882
intracellular receptor signaling pathwayGO:0030522740.879
induction by symbiont of host immune responseGO:005255910.874
positive regulation of lymphocyte activationGO:00512511400.872
t cell activationGO:00421102890.872
regulation of interferon gamma productionGO:0032649570.867
response to defense related host nitric oxide productionGO:005256520.859
positive regulation of response to cytokine stimulusGO:0060760110.855
regulation of response to cytokine stimulusGO:0060759230.855
regulation of peptidyl tyrosine phosphorylationGO:0050730930.851
nitric oxide synthase biosynthetic processGO:005176770.851
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005230210.845
reactive oxygen species metabolic processGO:0072593840.840
negative regulation of necroptotic processGO:006054690.839
positive regulation of antimicrobial peptide productionGO:000222510.838
Fly
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.838
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005234510.836
positive regulation by organism of immune response of other organism involved in symbiotic interactionGO:005255510.836
necroptotic processGO:0070266210.835
response to interleukin 18GO:007067340.834
peptidyl tyrosine phosphorylationGO:00181081430.830
nucleotide binding domain leucine rich repeat containing receptor signaling pathwayGO:003587260.825
interspecies interaction between organismsGO:0044419830.811
cell activation involved in immune responseGO:00022631260.811
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007043010.805
response to organic cyclic compoundGO:00140701980.802
cellular response to bacterial lipopeptideGO:007122130.800
positive regulation of mapk cascadeGO:00434101700.800
positive regulation of production of molecular mediator of immune responseGO:0002702450.799
Fly
cytokine production involved in immune responseGO:0002367340.795
reactive nitrogen species metabolic processGO:200105700.794
myd88 independent toll like receptor signaling pathwayGO:000275630.793
reactive oxygen species biosynthetic processGO:190340980.790
positive regulation of macrophage cytokine productionGO:006090770.787
regulation of interleukin 8 productionGO:003267730.787
regulation of interleukin 18 productionGO:003266130.786
interleukin 6 biosynthetic processGO:0042226120.784
cellular response to bacterial lipoproteinGO:007122030.781
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.777
regulation of interleukin 23 productionGO:003266720.775
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005226310.765
positive regulation of protein modification processGO:00314012990.765
regulation of alpha beta t cell proliferationGO:0046640180.764
peptidyl tyrosine modificationGO:00182121450.756
regulation of b cell activationGO:0050864810.749
regulation of antimicrobial humoral responseGO:000275930.747
Fly
alpha beta t cell activationGO:0046631910.746
response to immune response of other organism involved in symbiotic interactionGO:005256430.739
tumor necrosis factor productionGO:0032640500.737
response to defenses of other organism involved in symbiotic interactionGO:005217330.735
negative regulation of alpha beta t cell activationGO:0046636180.735
regulation of sequence specific dna binding transcription factor activityGO:00510901060.729
nitric oxide production involved in inflammatory responseGO:000253720.728
programmed necrotic cell deathGO:0097300280.728
regulation of cellular amine metabolic processGO:0033238200.727
drug transportGO:001589370.723
negative regulation of intracellular signal transductionGO:19025321670.719
positive regulation of interleukin 6 biosynthetic processGO:004541060.718
innate immune response activating cell surface receptor signaling pathwayGO:000222040.712
cd4 positive alpha beta t cell differentiationGO:0043367410.711
myeloid cell differentiationGO:00300992330.707
regulation of lymphocyte activationGO:00512492400.707
regulation of antibacterial peptide biosynthetic processGO:000280810.705
positive regulation of natural killer cell activationGO:0032816150.704
protein autophosphorylationGO:0046777610.700
cellular amine metabolic processGO:0044106440.699
negative regulation of cellular protein metabolic processGO:00322692470.698
negative regulation of tumor necrosis factor productionGO:0032720170.693
regulation of interferon beta productionGO:0032648130.687
regulation of reactive oxygen species metabolic processGO:2000377400.685
modulation by organism of defense response of other organism involved in symbiotic interactionGO:005225510.683
homeostasis of number of cellsGO:00488722100.683
response to exogenous dsrnaGO:0043330220.681
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.677
response to host immune responseGO:005257230.673
regulation of tumor necrosis factor biosynthetic processGO:0042534100.668
alpha beta t cell differentiation involved in immune responseGO:0002293300.665
regulation of chemokine biosynthetic processGO:004507380.661
response to interleukin 15GO:007067230.660
negative regulation of reactive oxygen species biosynthetic processGO:190342700.660
cd4 positive alpha beta t cell lineage commitmentGO:004337360.658
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.656
cellular amino acid metabolic processGO:00065201030.648
response to host defensesGO:005220030.648
leukocyte proliferationGO:00706611720.646
alpha beta t cell proliferationGO:0046633210.637
wound healing involved in inflammatory responseGO:000224640.631
mapk cascadeGO:00001652810.631
antibiotic transportGO:004289110.627
myeloid leukocyte activationGO:0002274830.624
negative regulation of phosphorus metabolic processGO:00105631840.623
response to interleukin 4GO:0070670230.621
positive regulation of stress activated mapk cascadeGO:0032874480.620
negative regulation of b cell activationGO:0050869270.618
peptidyl amino acid modificationGO:00181933360.615
regulation of inflammatory responseGO:00507271470.613
apoptotic signaling pathwayGO:00971903060.611
leukocyte apoptotic processGO:0071887710.610
negative regulation of t cell activationGO:0050868650.609
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.607
regulation of t cell activationGO:00508631700.604
induction by organism of defense response of other organism involved in symbiotic interactionGO:005225110.602
regulation of leukocyte differentiationGO:19021051590.602
t cell proliferationGO:00420981200.598
b cell proliferationGO:0042100530.595
toll like receptor 7 signaling pathwayGO:003415440.591
regulation of alpha beta t cell activationGO:0046634530.586
cellular response to interleukin 1GO:007134780.584
symbiosis encompassing mutualism through parasitismGO:0044403830.582
lymphocyte activation involved in immune responseGO:0002285930.581
negative regulation of lymphocyte proliferationGO:0050672450.575
positive regulation of apoptotic cell clearanceGO:200042730.573
negative regulation of lymphocyte activationGO:0051250910.570
regulation of interleukin 1 productionGO:0032652260.568
positive regulation of antibacterial peptide biosynthetic processGO:000696310.566
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.566
inflammatory responseGO:00069542440.560
negative regulation of phosphorylationGO:00423261660.557
inflammatory response to woundingGO:009059440.557
regulation of cd8 positive alpha beta cytotoxic t cell extravasationGO:200045220.555
positive regulation of t cell proliferationGO:0042102520.551
negative regulation of leukocyte proliferationGO:0070664460.543
regulation of natural killer cell differentiationGO:0032823110.542
cellular ketone metabolic processGO:0042180840.535
type i interferon biosynthetic processGO:004535190.531
negative regulation of phosphate metabolic processGO:00459361840.530
positive regulation of response to biotic stimulusGO:0002833150.528
Fly
regulation of stress activated mapk cascadeGO:0032872690.527
progesterone metabolic processGO:004244840.526
positive regulation by symbiont of host defense responseGO:005250910.519
negative regulation of interleukin 23 productionGO:003270710.518
growth involved in symbiotic interactionGO:0044110230.517
lymphocyte apoptotic processGO:0070227540.517
response to type i interferonGO:0034340120.513
i kappab phosphorylationGO:000725260.512
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.511
regulation of response to woundingGO:19030341890.507
interleukin 4 mediated signaling pathwayGO:003577120.503
regulation of inflammatory response to antigenic stimulusGO:0002861210.502
myd88 dependent toll like receptor signaling pathwayGO:000275570.499
negative regulation of cholesterol effluxGO:009037040.495
positive regulation of jun kinase activityGO:0043507300.491
positive regulation of inflammatory responseGO:0050729470.491
nitric oxide biosynthetic processGO:0006809250.490
regulation of mapk cascadeGO:00434082480.488
regulation of protein kinase activityGO:00458592320.481
negative regulation of nf kappab transcription factor activityGO:0032088150.481
regulation of nitric oxide biosynthetic processGO:0045428180.478
taurine metabolic processGO:001953040.477
lymphocyte proliferationGO:00466511640.474
defense response to bacteriumGO:00427421190.470
positive regulation of defense response to bacteriumGO:190042610.469
necroptotic signaling pathwayGO:009752730.460
positive regulation of cellular amine metabolic processGO:003324050.458
leukocyte homeostasisGO:0001776790.457
positive regulation by organism of defense response of other organism involved in symbiotic interactionGO:005251010.452
chloramphenicol transportGO:004289210.450
toll like receptor 3 signaling pathwayGO:003413840.437
modification by symbiont of host morphology or physiologyGO:004400340.430
stress activated mapk cascadeGO:0051403800.428
negative regulation of necrotic cell deathGO:0060547110.427
t cell homeostasisGO:0043029350.426
mast cell proliferationGO:007066240.424
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.422
response to tumor necrosis factorGO:0034612260.421
cellular response to oxidative stressGO:0034599760.420
regulation of peptidase activityGO:0052547960.418
interleukin 2 productionGO:0032623330.414
regulation of mast cell differentiationGO:006037530.412
negative regulation of innate immune responseGO:0045824170.409
protein modification by small protein conjugation or removalGO:00706472070.409
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.406
macrophage activationGO:0042116270.404
response to bacterial lipopeptideGO:007033930.404
production of molecular mediator involved in inflammatory responseGO:0002532210.404
regulation of growth of symbiont in hostGO:0044126190.402
regulation of cellular ketone metabolic processGO:0010565660.398
negative regulation of erk1 and erk2 cascadeGO:0070373210.397
eye photoreceptor cell differentiationGO:0001754410.394
regulation of defense response to virusGO:0050688180.393
regulation of natural killer cell activationGO:0032814220.384
cellular response to interleukin 4GO:0071353210.384
positive regulation of leukocyte mediated immunityGO:0002705700.373
antibacterial peptide biosynthetic processGO:000278020.371
positive regulation of immune effector processGO:00026991070.371
Fly
regulation of lipid transportGO:0032368360.371
regulation of cholesterol transportGO:0032374170.369
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043420.368
toxin transportGO:1901998380.366
interferon gamma productionGO:0032609670.364
regulation of tolerance inductionGO:0002643100.359
t cell activation involved in immune responseGO:0002286430.356
tyrosine phosphorylation of stat1 proteinGO:004250830.352
regulation of bindingGO:00510981110.346
antigen receptor mediated signaling pathwayGO:0050851640.346
cell surface pattern recognition receptor signaling pathwayGO:000275220.341
regulation of interleukin 10 productionGO:0032653210.341
positive regulation of cellular amino acid metabolic processGO:004576430.341
negative regulation of protein metabolic processGO:00512482820.338
tolerance inductionGO:0002507140.338
regulation of transferase activityGO:00513382630.336
positive regulation of atp biosynthetic processGO:200117120.336
interleukin 18 productionGO:003262140.335
regulation of protein tyrosine kinase activityGO:0061097170.330
positive regulation of interleukin 10 productionGO:0032733120.330
myeloid leukocyte cytokine productionGO:0061082120.330
isotype switching to ige isotypesGO:004828970.327
response to granulocyte macrophage colony stimulating factorGO:009701230.327
multicellular organismal homeostasisGO:00488711640.326
protein catabolic processGO:00301632210.326
interleukin 23 productionGO:003262720.322
positive regulation of glial cell proliferationGO:006025240.322
lymphocyte anergyGO:000224940.321
regulation of protein bindingGO:0043393600.318
regulation of interleukin 6 biosynthetic processGO:0045408110.317
regulation of multi organism processGO:00439001110.315
carbohydrate metabolic processGO:00059752300.313
intrinsic apoptotic signaling pathwayGO:00971931320.313
regulation of necrotic cell deathGO:0010939130.305
cd4 positive alpha beta t cell activationGO:0035710450.304
defense response to gram negative bacteriumGO:0050829280.303
positive regulation of adaptive immune responseGO:0002821610.300
macromolecule catabolic processGO:00090572810.299
negative regulation of growth of symbiont involved in interaction with hostGO:0044146190.297
regulation of mast cell proliferationGO:007066640.293
positive regulation of protein import into nucleus translocationGO:003316010.293
regulation of natural killer cell proliferationGO:003281720.291
negative regulation of interleukin 5 secretionGO:200066310.287
regulation of protein homodimerization activityGO:004349640.287
prolactin signaling pathwayGO:003816150.286
interferon alpha productionGO:003260770.279
cellular response to inorganic substanceGO:0071241370.278
positive regulation of tolerance inductionGO:000264580.277
positive regulation of apoptotic signaling pathwayGO:2001235950.276
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.274
t cell differentiationGO:00302171740.273
negative regulation of kinase activityGO:0033673810.270
macrophage fusionGO:003423830.268
antimicrobial peptide biosynthetic processGO:000277720.265
negative regulation of cell activationGO:00508661110.264
positive regulation of protein ubiquitinationGO:0031398270.263
positive regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042620.262
cellular response to granulocyte macrophage colony stimulating factor stimulusGO:009701130.259
positive regulation of multi organism processGO:0043902260.258
Fly
immunoglobulin productionGO:0002377730.258
regulation of defense response to bacteriumGO:190042430.258
t cell differentiation involved in immune responseGO:0002292300.255
interleukin 6 mediated signaling pathwayGO:007010260.253
positive regulation of map kinase activityGO:0043406840.250
growth of symbiont in hostGO:0044117230.247
regulation of acute inflammatory responseGO:0002673270.246
regulation of interleukin 2 productionGO:0032663280.243
regulation of antibacterial peptide productionGO:000278610.243
negative regulation of cell proliferationGO:00082852960.242
regulation of t cell proliferationGO:0042129920.242
positive regulation of b cell differentiationGO:0045579130.240
interleukin 12 biosynthetic processGO:004209080.240
immunoglobulin mediated immune responseGO:0016064690.239
dendritic cell differentiationGO:0097028260.236
stress activated protein kinase signaling cascadeGO:0031098810.231
alpha beta t cell lineage commitmentGO:000236370.228
positive regulation of bindingGO:0051099490.224
regulation of defense response to virus by hostGO:005069180.221
positive regulation of response to woundingGO:1903036660.220
regulation of type i interferon mediated signaling pathwayGO:006033870.218
nitric oxide metabolic processGO:0046209250.218
interleukin 13 secretionGO:007261120.217
positive regulation of acute inflammatory responseGO:0002675160.216
interleukin 12 productionGO:0032615320.216
regulation of protein transportGO:00512231630.215
valine metabolic processGO:000657340.214
positive regulation of nitric oxide biosynthetic processGO:0045429140.214
natural killer cell proliferationGO:000178730.214
positive regulation of interleukin 12 biosynthetic processGO:004508460.211
negative regulation of protein tyrosine kinase activityGO:006109930.211
regulation of interleukin 13 secretionGO:200066520.208
alpha beta t cell differentiationGO:0046632690.206
induction by symbiont of defense related host nitric oxide productionGO:005206310.204
negative regulation of molecular functionGO:00440922580.203
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.203
positive regulation of isotype switching to ige isotypesGO:004829540.202
epithelial tube morphogenesisGO:00605623030.201
jak stat cascadeGO:0007259420.200
isotype switchingGO:0045190360.200
regulation of mhc class ii biosynthetic processGO:004534670.200
cellular response to organonitrogen compoundGO:00714171450.199
positive regulation of interleukin 12 productionGO:0032735210.199
regulation of interleukin 1 alpha productionGO:003265040.196
t cell differentiation in thymusGO:0033077770.192
interleukin 5 secretionGO:007260320.189
b cell homeostasisGO:0001782340.188
coagulationGO:0050817780.188
negative regulation of immune effector processGO:0002698550.188
positive regulation of erk1 and erk2 cascadeGO:0070374470.187
regulation of apoptotic signaling pathwayGO:20012331970.187
leukocyte activation involved in immune responseGO:00023661260.187
regulation of interleukin 12 productionGO:0032655300.186
positive regulation of myeloid leukocyte cytokine production involved in immune responseGO:006108190.186
positive regulation of t cell activationGO:00508701010.186
positive regulation of gamma delta t cell activationGO:004664560.185
regulation of response to biotic stimulusGO:0002831380.183
Fly
t helper 1 cell lineage commitmentGO:000229620.181
regulation of interferon alpha productionGO:003264750.180
sterol transportGO:0015918380.178
response to reactive oxygen speciesGO:0000302560.178
positive regulation of protein phosphorylationGO:00019342420.177
t cell selectionGO:0045058340.177
positive regulation of b cell proliferationGO:0030890240.176
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.174
positive regulation of gamma delta t cell differentiationGO:004558860.173
regulation of leukocyte mediated immunityGO:00027031040.170
protein ubiquitinationGO:00165671710.170
regulation of carbohydrate metabolic processGO:0006109750.169
negative regulation of cytokine production involved in immune responseGO:000271950.169
somatic diversification of immune receptorsGO:0002200530.166
negative regulation of hydrolase activityGO:0051346710.165
interleukin 10 productionGO:0032613230.163
positive regulation of nitric oxide synthase biosynthetic processGO:005177060.162
b cell activation involved in immune responseGO:0002312500.160
detection of lipopolysaccharideGO:003249710.160
regulation of establishment of protein localizationGO:00702011810.158
t cell apoptotic processGO:0070231390.158
cellular response to interleukin 6GO:007135490.157
positive regulation of cytokine production involved in immune responseGO:0002720190.157
activation induced cell death of t cellsGO:0006924100.156
positive regulation of tyrosine phosphorylation of stat1 proteinGO:004251110.155
positive regulation of protein localization to nucleusGO:1900182300.152
leukocyte differentiationGO:00025213420.151
regulation of adaptive immune responseGO:0002819900.151
cholesterol effluxGO:0033344240.151
defense response to gram positive bacteriumGO:0050830500.150
positive regulation of antimicrobial humoral responseGO:000276020.149
Fly
interferon gamma mediated signaling pathwayGO:006033350.148
amine metabolic processGO:0009308450.148
development of secondary male sexual characteristicsGO:004654430.147
sensory perception of soundGO:0007605970.147
positive regulation of immature t cell proliferationGO:003309140.146
regulation of membrane potentialGO:00423911920.146
intestinal epithelial structure maintenanceGO:006072940.145
positive regulation of b cell mediated immunityGO:0002714260.145
positive regulation of isotype switchingGO:0045830150.145
regulation of chemokine secretionGO:009019640.143
positive regulation of kinase activityGO:00336741550.141
regulation of antigen receptor mediated signaling pathwayGO:0050854290.140
response to hostGO:007513630.139
regulation of interleukin 1 alpha secretionGO:005070530.139
negative regulation of transferase activityGO:0051348850.138
protein import into nucleus translocationGO:0000060120.138
positive regulation of activated t cell proliferationGO:004210480.137
regulation of ion transportGO:00432692150.137
defense response to fungusGO:0050832120.136
Fly
immune response activating cell surface receptor signaling pathwayGO:0002429720.136
modulation by symbiont of host immune responseGO:005255310.133
sulfur compound metabolic processGO:00067901000.133
regulation of hepatocyte proliferationGO:200034560.133
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.133

Myd88 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
retinal diseaseDOID:567900.708
sensory system diseaseDOID:005015500.708
disease of anatomical entityDOID:700.708
eye and adnexa diseaseDOID:149200.708
nervous system diseaseDOID:86300.708
eye diseaseDOID:561400.708
cancerDOID:16200.249
Human
disease of cellular proliferationDOID:1456600.249
Human
organ system cancerDOID:005068600.249
Human
retinal degenerationDOID:846600.149
degeneration of macula and posterior poleDOID:200700.132
macular degenerationDOID:444800.132