Mus musculus

194 known processes

Irs2

insulin receptor substrate 2

(Aliases: Irs-2)

Irs2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of insulin receptor signaling pathwayGO:0046626210.998
positive regulation of insulin receptor signaling pathwayGO:004662840.991
cellular response to peptide hormone stimulusGO:0071375920.947
monosaccharide metabolic processGO:00059961060.940
Human
monocarboxylic acid metabolic processGO:00327871910.939
Human
male germ line stem cell asymmetric divisionGO:004813320.937
Fly
cellular ketone metabolic processGO:0042180840.929
Human
regulation of glucan biosynthetic processGO:001096270.924
Human
carbohydrate metabolic processGO:00059752300.922
Human
carbohydrate biosynthetic processGO:0016051740.920
Human
regulation of cellular ketone metabolic processGO:0010565660.919
Human
regulation of glucose metabolic processGO:0010906600.919
Human
regulation of fatty acid metabolic processGO:0019217280.916
Human
connective tissue developmentGO:00614481790.905
regulation of fatty acid oxidationGO:0046320100.901
Human
regulation of feeding behaviorGO:006025930.884
cellular response to insulin stimulusGO:0032869780.874
negative regulation of triglyceride metabolic processGO:009020940.867
cellular response to peptideGO:1901653920.801
response to organonitrogen compoundGO:00102432460.799
response to peptide hormoneGO:00434341270.795
regulation of carbohydrate biosynthetic processGO:0043255400.792
Human
negative regulation of kinase activityGO:0033673810.791
multicellular organism growthGO:00352641610.786
Fly
regulation of cellular carbohydrate metabolic processGO:0010675750.784
Human
glucose metabolic processGO:0006006920.782
Human
polysaccharide metabolic processGO:0005976390.772
Human
generation of precursor metabolites and energyGO:00060911030.768
Human
insulin receptor signaling pathwayGO:0008286490.759
glucan biosynthetic processGO:0009250140.743
Human
response to peptideGO:19016521360.740
cellular response to hormone stimulusGO:00328701500.712
hexose biosynthetic processGO:0019319390.693
regulation of gluconeogenesisGO:0006111300.691
lipid biosynthetic processGO:00086101790.691
response to testosteroneGO:003357430.677
regulation of cellular amine metabolic processGO:0033238200.675
response to insulinGO:00328681000.669
negative regulation of molecular functionGO:00440922580.668
glycogen biosynthetic processGO:0005978140.667
Human
gluconeogenesisGO:0006094390.665
neutral lipid metabolic processGO:0006638570.664
cellular carbohydrate metabolic processGO:00442621190.659
Human
regulation of fatty acid beta oxidationGO:003199810.611
Human
positive regulation of glucose metabolic processGO:0010907210.597
Human
monosaccharide biosynthetic processGO:0046364440.591
vitellogenesisGO:000729620.590
Fly
positive regulation of fatty acid oxidationGO:004632140.572
Human
positive regulation of male gonad developmentGO:200002060.562
regulation of cellular amino acid metabolic processGO:000652150.558
nitrogen compound transportGO:00717052710.555
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.553
regulation of triglyceride metabolic processGO:0090207170.550
energy reserve metabolic processGO:0006112390.542
Human
mitotic cell cycleGO:00002781950.539
germline stem cell asymmetric divisionGO:009872820.529
Fly
regulation of triglyceride biosynthetic processGO:0010866100.528
regulation of protein serine threonine kinase activityGO:00719001570.524
positive regulation of carbohydrate metabolic processGO:0045913300.520
Human
lipid catabolic processGO:0016042690.509
Human Mouse
response to organic cyclic compoundGO:00140701980.502
regionalizationGO:00030023370.501
negative regulation of cellular response to insulin stimulusGO:1900077160.493
oxidation reduction processGO:00551143420.493
Human
regulation of kinase activityGO:00435492490.492
regulation of glycogen metabolic processGO:0070873130.490
Human
regulation of lipid metabolic processGO:00192161180.481
Human Mouse
spermatogenesisGO:00072832840.477
Fly
regulation of sequence specific dna binding transcription factor activityGO:00510901060.473
negative regulation of cell proliferationGO:00082852960.471
regulation of protein kinase activityGO:00458592320.469
positive regulation of cellular catabolic processGO:00313311480.464
Human
response to oxygen levelsGO:0070482620.460
Fly
cellular glucan metabolic processGO:0006073320.458
Human
sterol homeostasisGO:0055092450.456
organ growthGO:00352651170.456
Fly
acylglycerol metabolic processGO:0006639550.451
negative regulation of insulin receptor signaling pathwayGO:0046627140.433
cartilage development involved in endochondral bone morphogenesisGO:0060351240.431
regulation of myeloid leukocyte differentiationGO:0002761580.428
response to radiationGO:00093141650.419
hexose metabolic processGO:0019318980.418
Human
regulation of organelle organizationGO:00330432890.409
negative regulation of protein metabolic processGO:00512482820.405
polysaccharide biosynthetic processGO:0000271200.401
Human
peptidyl amino acid modificationGO:00181933360.398
regulation of glycogen biosynthetic processGO:000597970.393
Human
regulation of fat cell differentiationGO:0045598810.391
cellular amino acid metabolic processGO:00065201030.386
glucan metabolic processGO:0044042320.384
Human
response to extracellular stimulusGO:00099911270.379
Fly
negative regulation of cellular amino acid metabolic processGO:004576300.377
male gamete generationGO:00482322850.372
Fly
positive regulation of organelle organizationGO:00106381280.366
positive regulation of transferase activityGO:00513471670.364
Mouse
regulation of nitrogen cycle metabolic processGO:190331410.360
positive regulation of inositol phosphate biosynthetic processGO:006073220.359
triglyceride metabolic processGO:0006641510.357
carbohydrate transportGO:0008643620.353
Human
female mating behaviorGO:006018080.351
regulation of cell migrationGO:00303342190.350
regulation of neuron deathGO:19012141340.344
regulation of lipid catabolic processGO:0050994150.343
Human
endochondral bone morphogenesisGO:0060350500.342
cardiocyte differentiationGO:0035051870.342
negative regulation of triglyceride biosynthetic processGO:001086820.342
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.331
negative regulation of feeding behaviorGO:200025210.331
histone acetylationGO:0016573410.329
erythrocyte differentiationGO:0030218880.328
cell fate commitmentGO:00451652100.324
positive regulation of growthGO:00459271040.322
Fly
positive regulation of hormone secretionGO:0046887380.322
fat cell differentiationGO:00454441600.317
adult behaviorGO:00305341350.315
germ cell developmentGO:00072811850.308
Fly
glycerolipid metabolic processGO:00464861220.307
Mouse
acylglycerol biosynthetic processGO:0046463180.304
maintenance of locationGO:0051235890.303
regulation of bindingGO:00510981110.303
inflammatory responseGO:00069542440.300
positive regulation of cellular amine metabolic processGO:003324050.295
myeloid cell differentiationGO:00300992330.290
cellular amine metabolic processGO:0044106440.289
cholesterol homeostasisGO:0042632440.286
steroid metabolic processGO:00082021190.285
negative regulation of transferase activityGO:0051348850.285
brain segmentationGO:003528430.284
regulation of circadian sleep wake cycle sleepGO:004518730.283
regulation of mapk cascadeGO:00434082480.283
neuron apoptotic processGO:00514021420.281
endocrine system developmentGO:0035270980.277
negative regulation of cellular carbohydrate metabolic processGO:0010677190.275
ossificationGO:00015032160.275
axonogenesisGO:00074092740.275
positive regulation of protein serine threonine kinase activityGO:00719021060.273
circadian sleep wake cycleGO:004274550.272
regulation of peptide transportGO:0090087910.270
urogenital system developmentGO:00016552610.269
regulation of cellular catabolic processGO:00313292420.268
Human
muscle cell differentiationGO:00426922610.268
blastocyst growthGO:0001832230.268
organic acid catabolic processGO:0016054510.268
Human
negative regulation of insulin secretionGO:0046676140.264
negative regulation of intracellular signal transductionGO:19025321670.263
developmental maturationGO:00217001930.263
glycerolipid biosynthetic processGO:0045017500.263
organic hydroxy compound metabolic processGO:19016152030.262
regulation of circadian sleep wake cycleGO:004274930.261
positive regulation of cellular carbohydrate metabolic processGO:0010676290.259
Human
negative regulation of gluconeogenesisGO:004572190.258
skeletal system developmentGO:00015013560.256
glycogen metabolic processGO:0005977320.256
Human
germ line stem cell divisionGO:004207820.256
Fly
macroautophagyGO:0016236210.255
regulation of circadian rhythmGO:0042752580.254
negative regulation of cellular protein metabolic processGO:00322692470.250
regulation of cellular response to insulin stimulusGO:1900076300.249
circadian regulation of gene expressionGO:0032922480.249
development of primary female sexual characteristicsGO:0046545730.247
embryonic organ morphogenesisGO:00485622760.245
triglyceride biosynthetic processGO:0019432170.243
regulation of hormone levelsGO:00108172110.241
female gonad developmentGO:0008585710.240
cellular polysaccharide metabolic processGO:0044264380.238
Human
autophagyGO:0006914450.238
regulation of transferase activityGO:00513382630.231
cell type specific apoptotic processGO:00972852680.231
amine metabolic processGO:0009308450.230
neuron deathGO:00709971540.227
lipid modificationGO:0030258650.226
Human Mouse
cellular response to cytokine stimulusGO:00713451890.226
regulation of intracellular transportGO:00323861590.225
bone developmentGO:00603481200.224
negative regulation of phosphorylationGO:00423261660.223
regulation of androgen receptor signaling pathwayGO:006076530.220
cytoplasmic transportGO:00164822340.215
regulation of peptide secretionGO:0002791770.215
positive regulation of mapk cascadeGO:00434101700.214
stem cell divisionGO:0017145300.214
Fly
embryonic placenta developmentGO:0001892980.212
posttranscriptional regulation of gene expressionGO:00106081550.211
regulation of leukocyte differentiationGO:19021051590.208
organic anion transportGO:00157111370.207
Human
monocarboxylic acid catabolic processGO:0072329270.206
Human
negative regulation of fatty acid metabolic processGO:0045922100.201
type i pneumocyte differentiationGO:006050970.199
small molecule catabolic processGO:0044282710.197
Human
negative regulation of peptide secretionGO:0002792160.197
regulation of translationGO:0006417710.197
negative regulation of neuron deathGO:1901215980.194
negative regulation of neuron apoptotic processGO:0043524920.193
negative regulation of fat cell differentiationGO:0045599360.192
wnt signaling pathway involved in kidney developmentGO:006128920.192
positive regulation of protein phosphorylationGO:00019342420.192
asymmetric neuroblast divisionGO:005505910.189
negative regulation of cellular amine metabolic processGO:003323910.186
fatty acid metabolic processGO:00066311210.186
Human
response to alkaloidGO:0043279340.182
cellular polysaccharide biosynthetic processGO:0033692190.180
Human
transdifferentiationGO:006029010.179
neural precursor cell proliferationGO:00613511210.178
mapk cascadeGO:00001652810.176
positive regulation of protein kinase activityGO:00458601440.175
glucose importGO:0046323320.173
Human
cellular response to steroid hormone stimulusGO:0071383330.173
negative regulation of hydrolase activityGO:0051346710.172
regulation of carbohydrate metabolic processGO:0006109750.169
Human
response to purine containing compoundGO:0014074280.168
positive regulation of insulin secretionGO:0032024260.166
negative regulation of peptide hormone secretionGO:0090278160.166
regulation of cellular response to stressGO:00801351590.166
negative regulation of lipid metabolic processGO:0045833300.165
lipid transportGO:0006869980.164
Human
negative regulation of protein phosphorylationGO:00019331260.164
bile acid metabolic processGO:0008206170.162
skeletal muscle cell differentiationGO:0035914660.162
lipid oxidationGO:0034440290.161
Human
internal protein amino acid acetylationGO:0006475420.160
hindbrain developmentGO:00309021280.160
regulation of myeloid cell differentiationGO:0045637960.160
negative regulation of androgen receptor signaling pathwayGO:006076630.157
lipid localizationGO:00108761260.154
Human
positive regulation of kinase activityGO:00336741550.150
Mouse
peptidyl lysine acetylationGO:0018394450.148
response to inorganic substanceGO:0010035960.146
inner ear morphogenesisGO:00424721010.145
establishment or maintenance of epithelial cell apical basal polarityGO:0045197140.145
locomotory behaviorGO:00076261950.144
anion transportGO:00068201770.144
Human
cellular amide metabolic processGO:0043603580.144
intracellular protein transportGO:00068862040.143
positive regulation of neuron differentiationGO:00456661410.143
protein acylationGO:0043543640.143
male meiosis iGO:0007141160.142
response to nutrient levelsGO:00316671090.142
Fly
regulation of autophagic vacuole assemblyGO:200078540.140
insulin secretionGO:0030073890.139
positive regulation of cell cycleGO:0045787920.139
small molecule biosynthetic processGO:00442831320.139
regulation of cell cycleGO:00517262810.139
cellular lipid metabolic processGO:00442553230.137
Human Mouse
alpha amino acid metabolic processGO:1901605590.137
negative regulation of translational initiationGO:004594740.137
peptide transportGO:00158331330.137
regulation of cell motilityGO:20001452360.136
g protein coupled receptor signaling pathwayGO:00071862430.136
chromatin organizationGO:00063252060.135
cellular response to dna damage stimulusGO:00069742070.134
sensory organ morphogenesisGO:00905962420.130
response to decreased oxygen levelsGO:0036293590.130
Fly
appendage developmentGO:00487361660.129
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.129
chromatin modificationGO:00165681870.123
cell maturationGO:00484691270.123
positive regulation of fatty acid beta oxidationGO:003200010.122
Human
regulation of peptidyl lysine acetylationGO:2000756220.122
olfactory learningGO:000835520.121
Fly
lactationGO:0007595250.121
positive regulation of lipid metabolic processGO:0045834400.121
Human Mouse
regulation of vacuole organizationGO:004408840.121
neutral lipid biosynthetic processGO:0046460180.120
gland developmentGO:00487323300.118
insulin like growth factor receptor signaling pathwayGO:0048009210.116
regulation of response to reactive oxygen speciesGO:190103190.116
regulation of secretion by cellGO:19035302490.115
wnt signaling pathwayGO:00160551880.113
anoikisGO:004327660.113
negative regulation of cell motilityGO:2000146610.112
negative regulation of protein modification processGO:00314001630.110
associative learningGO:0008306610.109
Fly
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.109
nucleocytoplasmic transportGO:00069131390.106
glucose homeostasisGO:00425931280.106
establishment of protein localization to organelleGO:00725941180.105
lung epithelial cell differentiationGO:0060487290.104
positive regulation of stem cell proliferationGO:2000648590.104
regulation of activin receptor signaling pathwayGO:0032925100.104
Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.104
Fly
negative regulation of translationGO:0017148220.104
response to hypoxiaGO:0001666580.104
creatinine metabolic processGO:004644930.102
negative regulation of protein kinase b signalingGO:0051898180.100
amide transportGO:00428861380.100
histone h3 deacetylationGO:007093280.100
ear developmentGO:00435832000.099
lung cell differentiationGO:0060479300.099
regulation of polysaccharide metabolic processGO:0032881130.098
Human
positive regulation of programmed cell deathGO:00430682180.097
regulation of hormone secretionGO:0046883880.096
phosphatidylinositol mediated signalingGO:0048015410.096
glucose transportGO:0015758560.095
Human
regulation of glutamine family amino acid metabolic processGO:000082010.095
cartilage developmentGO:00512161400.095
cellular chemical homeostasisGO:00550822150.094
limb morphogenesisGO:00351081490.094
forebrain developmentGO:00309003020.094
epithelial tube morphogenesisGO:00605623030.094
regulation of mitotic cell cycleGO:00073461260.093
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021340.092
carbohydrate derivative biosynthetic processGO:19011371830.092
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.092
heart morphogenesisGO:00030071780.090
regulation of generation of precursor metabolites and energyGO:0043467380.090
Human
rhythmic processGO:00485111740.090
regulation of lipid biosynthetic processGO:0046890540.089
epidermis developmentGO:00085441870.088
fatty acid beta oxidationGO:0006635160.088
Human
aortic valve morphogenesisGO:000318040.088
antral ovarian follicle growthGO:000154750.087
epithelial cell developmentGO:00020641590.086
cellular response to gonadotropin stimulusGO:007137140.086
bmp signaling pathwayGO:0030509930.085
regulation of polysaccharide biosynthetic processGO:003288570.085
Human
cation transportGO:00068123990.084
regulation of protein import into nucleus translocationGO:003315820.084
diencephalon developmentGO:0021536630.083
organophosphate biosynthetic processGO:00904071220.083
osteoclast differentiationGO:0030316620.083
lymphocyte differentiationGO:00300982420.083
intracellular receptor signaling pathwayGO:0030522740.083
positive regulation of protein modification processGO:00314012990.083
organelle localizationGO:00516401790.081
fatty acid catabolic processGO:0009062250.081
Human
fibroblast proliferationGO:0048144350.081
positive regulation of peptide secretionGO:0002793330.079
female sex differentiationGO:0046660840.079
regulation of fibroblast proliferationGO:0048145340.078
cell growthGO:00160491300.078
Fly
intracellular steroid hormone receptor signaling pathwayGO:0030518290.078
regulation of dna bindingGO:0051101390.078
regulation of dna templated transcription in response to stressGO:004362090.078
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288120.077
hormone mediated signaling pathwayGO:0009755230.077
regulation of peptide hormone secretionGO:0090276750.077
male gonad developmentGO:0008584880.077
negative regulation of circadian rhythmGO:004275480.077
regulation of steroid hormone biosynthetic processGO:009003040.077
t cell activationGO:00421102890.077
protein autophosphorylationGO:0046777610.076
inositol phosphate biosynthetic processGO:003295860.076
regulation of steroid biosynthetic processGO:0050810260.075
regulation of glucagon secretionGO:007009220.075
monosaccharide transportGO:0015749580.075
Human
catecholamine metabolic processGO:0006584300.075
purine containing compound metabolic processGO:00725213110.074
regulation of neuron projection developmentGO:00109751690.074
developmental cell growthGO:0048588840.073
Fly
peptidyl lysine modificationGO:0018205770.072
axon guidanceGO:00074111410.072
response to acid chemicalGO:00011011110.072
cellular response to organonitrogen compoundGO:00714171450.072
organonitrogen compound biosynthetic processGO:19015661920.072
negative regulation of phosphorus metabolic processGO:00105631840.072
cellular response to starvationGO:0009267570.072
cellular response to external stimulusGO:0071496880.072
synaptic transmissionGO:00072683290.071
autophagic vacuole assemblyGO:0000045130.071
positive regulation of cellular response to insulin stimulusGO:190007890.070
regulation of bmp signaling pathwayGO:0030510600.070
telencephalon developmentGO:00215371860.070
regulation of glucose transportGO:0010827320.070
Human
mammary gland lobule developmentGO:0061377220.069
cell proliferation in hindbrainGO:0021534100.068
succinate metabolic processGO:000610540.068
cerebellum developmentGO:0021549770.068
regulation of fatty acid biosynthetic processGO:0042304120.067
positive regulation of lipid catabolic processGO:005099660.067
Human
placenta developmentGO:00018901400.067
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.066
energy derivation by oxidation of organic compoundsGO:0015980770.066
Human
circadian rhythmGO:00076231140.066
striated muscle tissue developmentGO:00147062930.066
sensory system developmentGO:004888030.066
negative regulation of growthGO:0045926990.065
positive regulation of fibroblast proliferationGO:0048146200.065
neuron projection guidanceGO:00974851410.065
cerebellar purkinje cell layer developmentGO:0021680260.065
cognitionGO:00508901490.065
Fly
regulation of system processGO:00440572000.064
b cell activationGO:00421131610.064
cytokine mediated signaling pathwayGO:00192211150.064
regulation of exit from mitosisGO:000709610.064
b cell proliferationGO:0042100530.064
positive regulation of cholesterol transportGO:003237690.064
regulation of cell morphogenesis involved in differentiationGO:00107691510.063
myeloid leukocyte differentiationGO:00025731190.063
acetylcholine transportGO:001587020.063
protein deacetylationGO:0006476320.063
development of primary sexual characteristicsGO:00451371430.063
negative regulation of secretion by cellGO:1903531540.063
regulation of protein transportGO:00512231630.062
cellular response to oxidative stressGO:0034599760.062
stem cell proliferationGO:00720891170.062
positive regulation of neuron apoptotic processGO:0043525250.062
positive regulation of cell deathGO:00109422240.062
regulation of renal sodium excretionGO:003581330.062
cellular response to metal ionGO:0071248310.061
positive regulation of transcription from rna polymerase i promoterGO:004594330.061
exocrine pancreas developmentGO:003101770.061
jak stat cascadeGO:0007259420.061
cell divisionGO:00513011200.061
Fly
regulation of endopeptidase activityGO:0052548890.061
regulation of neurotransmitter uptakeGO:005158060.061
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.060
positive regulation of reproductive processGO:2000243190.060
regulation of mast cell differentiationGO:006037530.059
protein localization to nucleusGO:00345041210.059
Mouse
negative regulation of release of cytochrome c from mitochondriaGO:009020160.059
regulation of protein localizationGO:00328802310.059
glycoprotein metabolic processGO:00091001160.059
alpha beta t cell differentiationGO:0046632690.059
regulation of organ growthGO:0046620610.059
Fly
positive regulation of nervous system developmentGO:00519622210.059
regulation of male gonad developmentGO:200001870.059
cellular response to nutrient levelsGO:0031669640.059
sulfur compound biosynthetic processGO:0044272370.058
regulation of inflammatory responseGO:00507271470.058
kidney epithelium developmentGO:00720731210.058
regulation of cell growthGO:0001558910.057
regulation of phosphate transportGO:001096610.057
bone morphogenesisGO:0060349780.057
response to starvationGO:0042594650.057
Fly
carboxylic acid transportGO:00469421000.056
Human
regulation of b cell apoptotic processGO:0002902130.056
renal sodium excretionGO:003581230.056
negative regulation of creb transcription factor activityGO:003279220.056
angiogenesisGO:00015252010.056
cellular response to extracellular stimulusGO:0031668810.056
lipid storageGO:0019915360.056
central nervous system segmentationGO:003528330.056
positive regulation of glucose transportGO:0010828160.056
Human
digestive system developmentGO:00551232000.056
regulation of neuron apoptotic processGO:00435231220.056
ammonia assimilation cycleGO:001967620.056
response to ammonium ionGO:0060359210.056
glycoprotein biosynthetic processGO:0009101890.055
embryonic hemopoiesisGO:0035162230.055
response to amphetamineGO:0001975160.055
ear morphogenesisGO:00424711180.055
circulatory system processGO:00030131970.055
regulation of sterol transportGO:0032371170.055
organelle fissionGO:00482851700.054
glucose import in response to insulin stimulusGO:004438180.054
positive regulation of inositol trisphosphate biosynthetic processGO:003296220.054
vacuole organizationGO:0007033380.053
activin receptor signaling pathwayGO:0032924180.053
Fly
regulation of striated muscle cell differentiationGO:0051153810.053
regulation of ion transportGO:00432692150.053
Human
pancreas developmentGO:0031016570.053
regulation of intracellular protein transportGO:0033157820.053
feeding behaviorGO:0007631620.052
muscle tissue developmentGO:00605373080.052
multi organism behaviorGO:0051705620.052
monocarboxylic acid biosynthetic processGO:0072330610.052
histone h3 acetylationGO:0043966140.052
segmentationGO:0035282930.051
protein localization to organelleGO:00333651850.051
Mouse
peptide secretionGO:00027901140.051
cell fate determinationGO:0001709320.051
response to iron ionGO:001003940.051
cyclic purine nucleotide metabolic processGO:0052652430.051
negative regulation of myeloid cell differentiationGO:0045638380.051
regulation of cytoplasmic transportGO:19036491120.051
cardiac muscle tissue developmentGO:00487381300.051
regulation of inositol trisphosphate biosynthetic processGO:003296030.050
regulation of cell cycle processGO:00105641600.050
regulation of b cell proliferationGO:0030888390.050
macromolecule methylationGO:00434141200.050
regulation of stem cell proliferationGO:0072091780.050
positive regulation of sterol transportGO:003237390.050
negative regulation of phosphate metabolic processGO:00459361840.050
positive regulation of smooth muscle cell migrationGO:001491140.050
blastocyst developmentGO:0001824800.049
phosphatidylinositol 3 kinase signalingGO:0014065360.049
organic hydroxy compound transportGO:0015850930.049
limb developmentGO:00601731660.049
columnar cuboidal epithelial cell differentiationGO:0002065820.049
negative regulation of glycogen metabolic processGO:007087420.049
nuclear importGO:0051170950.049
negative regulation of glycogen biosynthetic processGO:004571910.049
alcohol metabolic processGO:00060661160.048
cholesterol transportGO:0030301380.048

Irs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.819
Human
inherited metabolic disorderDOID:65500.664
diabetes mellitusDOID:935100.349
Human
type 2 diabetes mellitusDOID:935200.349
Human
carbohydrate metabolism diseaseDOID:005001300.349
Human
glucose metabolism diseaseDOID:419400.349
Human
acquired metabolic diseaseDOID:006015800.349
Human
spinocerebellar degenerationDOID:247800.205
spinocerebellar ataxiaDOID:144100.205
central nervous system diseaseDOID:33100.205
disease of anatomical entityDOID:700.205
neurodegenerative diseaseDOID:128900.205
nervous system diseaseDOID:86300.205
carbohydrate metabolic disorderDOID:297800.073
immune system diseaseDOID:291400.059