Mus musculus

0 known processes

Pdk3

pyruvate dehydrogenase kinase, isoenzyme 3

(Aliases: 2610001M10Rik,AI035637,MGC6383)

Pdk3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular catabolic processGO:00313292420.104
nucleotide metabolic processGO:00091173320.091
cellular nitrogen compound catabolic processGO:00442702800.078
negative regulation of cellular protein metabolic processGO:00322692470.077
nucleoside phosphate metabolic processGO:00067533380.074
organic cyclic compound catabolic processGO:19013612950.074
nucleobase containing small molecule metabolic processGO:00550863520.072
ribose phosphate metabolic processGO:00196932910.064
cellular amino acid metabolic processGO:00065201030.059
negative regulation of protein metabolic processGO:00512482820.059
regulation of purine nucleotide catabolic processGO:00331211220.059
heterocycle catabolic processGO:00467002800.058
carbohydrate metabolic processGO:00059752300.056
Human
positive regulation of cellular catabolic processGO:00313311480.054
aromatic compound catabolic processGO:00194392860.053
oxidation reduction processGO:00551143420.049
small gtpase mediated signal transductionGO:0007264970.049
organonitrogen compound catabolic processGO:19015652640.048
intracellular protein transportGO:00068862040.047
purine nucleotide metabolic processGO:00061633020.046
glycosyl compound metabolic processGO:19016572460.046
ribonucleotide metabolic processGO:00092592910.045
regulation of organelle organizationGO:00330432890.045
ion transmembrane transportGO:00342203610.045
positive regulation of nucleotide catabolic processGO:0030813880.042
glycosyl compound catabolic processGO:19016582060.042
ribonucleoside metabolic processGO:00091192450.041
positive regulation of cellular amine metabolic processGO:003324050.041
nitrogen compound transportGO:00717052710.041
nucleoside metabolic processGO:00091162460.041
ribonucleoside catabolic processGO:00424542060.040
purine containing compound catabolic processGO:00725232130.040
positive regulation of purine nucleotide metabolic processGO:19005441140.040
nucleotide catabolic processGO:00091662170.040
regulation of hydrolase activityGO:00513362460.039
nucleoside catabolic processGO:00091642060.039
purine containing compound metabolic processGO:00725213110.039
cation transportGO:00068123990.039
carbohydrate derivative catabolic processGO:19011362310.038
organophosphate catabolic processGO:00464342320.037
cellular ketone metabolic processGO:0042180840.037
Human Mouse
regulation of nucleotide metabolic processGO:00061401690.037
negative regulation of molecular functionGO:00440922580.037
cellular macromolecule catabolic processGO:00442652060.036
amine metabolic processGO:0009308450.036
nadph regenerationGO:000674020.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
cellular amine metabolic processGO:0044106440.035
purine ribonucleoside metabolic processGO:00461282410.035
purine nucleoside catabolic processGO:00061522050.034
purine ribonucleotide catabolic processGO:00091542080.034
ras protein signal transductionGO:0007265770.034
negative regulation of protein modification processGO:00314001630.034
spermatogenesisGO:00072832840.034
microtubule cytoskeleton organizationGO:00002261570.033
monocarboxylic acid metabolic processGO:00327871910.033
Human Mouse
cytoplasmic transportGO:00164822340.033
carbohydrate derivative biosynthetic processGO:19011371830.033
regulation of cellular amine metabolic processGO:0033238200.033
peptide transportGO:00158331330.032
purine nucleoside metabolic processGO:00422782410.032
regulation of purine nucleotide metabolic processGO:19005421690.032
apoptotic signaling pathwayGO:00971903060.032
transmembrane transportGO:00550854120.031
response to oxidative stressGO:00069791230.031
purine ribonucleoside catabolic processGO:00461302050.031
negative regulation of phosphate metabolic processGO:00459361840.030
protein targetingGO:00066051430.030
homeostasis of number of cellsGO:00488722100.030
negative regulation of phosphorus metabolic processGO:00105631840.030
mitotic cell cycle processGO:19030471590.030
positive regulation of hydrolase activityGO:00513451480.030
regulation of cellular ketone metabolic processGO:0010565660.029
Human Mouse
macromolecule catabolic processGO:00090572810.029
mitotic cytokinesisGO:000028140.029
nucleoside triphosphate metabolic processGO:00091412300.029
positive regulation of purine nucleotide catabolic processGO:0033123880.028
purine ribonucleotide metabolic processGO:00091502900.028
organophosphate biosynthetic processGO:00904071220.028
positive regulation of organelle organizationGO:00106381280.028
coenzyme metabolic processGO:0006732520.027
Human Mouse
organelle fissionGO:00482851700.027
regulation of cell cycle processGO:00105641600.027
positive regulation of nucleotide metabolic processGO:00459811140.027
purine nucleotide catabolic processGO:00061952110.027
regulation of cellular amino acid metabolic processGO:000652150.026
nucleoside phosphate catabolic processGO:19012922220.026
ribonucleoside triphosphate metabolic processGO:00091992200.026
purine nucleoside triphosphate catabolic processGO:00091462030.026
inorganic ion transmembrane transportGO:00986602340.026
cellular lipid metabolic processGO:00442553230.026
Human Mouse
purine ribonucleoside triphosphate metabolic processGO:00092052200.026
positive regulation of nucleoside metabolic processGO:0045979910.025
purine nucleoside triphosphate metabolic processGO:00091442260.025
regulation of nucleoside metabolic processGO:00091181300.025
regulation of hormone levelsGO:00108172110.025
sulfur compound metabolic processGO:00067901000.025
Human Mouse
cytokinetic processGO:003250620.025
positive regulation of gtpase activityGO:0043547850.024
protein catabolic processGO:00301632210.024
regulation of cellular component biogenesisGO:00440871810.024
cellular response to lipidGO:00713961450.024
Human
regulation of gtp catabolic processGO:00331241130.024
ribonucleoside triphosphate catabolic processGO:00092031990.024
positive regulation of cell cycleGO:0045787920.024
regulation of cytoskeleton organizationGO:00514931220.024
small molecule biosynthetic processGO:00442831320.024
maintenance of locationGO:0051235890.023
cation transmembrane transportGO:00986552660.023
cofactor metabolic processGO:0051186800.023
Human Mouse
cellular response to dna damage stimulusGO:00069742070.023
ribonucleotide catabolic processGO:00092612080.023
negative regulation of cellular component organizationGO:00511291940.023
regulation of mitotic cell cycleGO:00073461260.023
anion transportGO:00068201770.023
protein complex disassemblyGO:0043241400.023
posttranscriptional regulation of gene expressionGO:00106081550.023
negative regulation of phosphorylationGO:00423261660.023
positive regulation of protein modification processGO:00314012990.023
protein localization to organelleGO:00333651850.023
membrane organizationGO:00610242450.023
wnt signaling pathwayGO:00160551880.023
meiotic cell cycleGO:00513211220.022
lipid biosynthetic processGO:00086101790.022
cellular protein catabolic processGO:00442571550.022
mitotic cell cycleGO:00002781950.022
retrograde transport endosome to golgiGO:004214720.021
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
organonitrogen compound biosynthetic processGO:19015661920.021
positive regulation of apoptotic processGO:00430652170.021
cellular chemical homeostasisGO:00550822150.021
guanosine containing compound catabolic processGO:19010691440.021
nuclear importGO:0051170950.021
pyridine nucleotide biosynthetic processGO:001936340.021
nucleocytoplasmic transportGO:00069131390.021
dna replication independent nucleosome assemblyGO:000633610.020
organic hydroxy compound metabolic processGO:19016152030.020
microtubule based processGO:00070172360.020
regulation of protein transportGO:00512231630.020
peptidyl amino acid modificationGO:00181933360.020
Human
cell type specific apoptotic processGO:00972852680.020
protein localization to nucleusGO:00345041210.020
positive regulation of gtp catabolic processGO:0033126850.020
regulation of nucleotide catabolic processGO:00308111220.019
regulation of intracellular protein transportGO:0033157820.019
regulation of cell cycleGO:00517262810.019
cellular homeostasisGO:00197252400.019
negative regulation of intracellular signal transductionGO:19025321670.019
nuclear divisionGO:00002801580.019
muscle cell differentiationGO:00426922610.019
regulation of kinase activityGO:00435492490.019
oocyte constructionGO:000730820.018
protein maturationGO:00516041760.018
amide transportGO:00428861380.018
establishment of protein localization to organelleGO:00725941180.018
nucleoside triphosphate catabolic processGO:00091432050.018
glucose metabolic processGO:0006006920.018
Human
protein importGO:00170381010.018
organelle assemblyGO:00709251770.018
regulation of transferase activityGO:00513382630.018
peptide hormone secretionGO:00300721090.018
regulation of protein localizationGO:00328802310.018
nuclear transportGO:00511691390.018
protein modification by small protein conjugation or removalGO:00706472070.018
guanosine containing compound metabolic processGO:19010681440.017
camera type eye developmentGO:00430102660.017
negative regulation of protein phosphorylationGO:00019331260.017
compound eye developmentGO:004874910.017
response to inorganic substanceGO:0010035960.017
regulation of microtubule based processGO:0032886520.017
asymmetric stem cell divisionGO:009872230.017
negative regulation of cell cycle processGO:0010948690.017
striated muscle tissue developmentGO:00147062930.017
germ cell developmentGO:00072811850.017
glucose catabolic processGO:000600730.017
inorganic cation transmembrane transportGO:00986622070.017
carbohydrate homeostasisGO:00335001280.017
mrna metabolic processGO:0016071840.017
male gamete generationGO:00482322850.016
regulation of cell projection organizationGO:00313442060.016
regulation of mapk cascadeGO:00434082480.016
protein import into nucleusGO:0006606950.016
positive regulation of protein phosphorylationGO:00019342420.016
mapk cascadeGO:00001652810.016
regulation of apoptotic signaling pathwayGO:20012331970.016
cellular response to hormone stimulusGO:00328701500.016
cell adhesionGO:00071553290.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
regulation of cytoplasmic transportGO:19036491120.016
meiosis iGO:0007127600.016
sensory perceptionGO:00076002450.016
development of primary sexual characteristicsGO:00451371430.016
negative regulation of organelle organizationGO:0010639900.016
hormone secretionGO:00468791280.015
dephosphorylationGO:00163111290.015
regulation of secretion by cellGO:19035302490.015
glucose homeostasisGO:00425931280.015
nicotinamide nucleotide biosynthetic processGO:001935940.015
regulation of secretionGO:00510462740.015
positive regulation of cell cycle processGO:0090068610.015
sensory organ morphogenesisGO:00905962420.015
endocytosisGO:00068971680.015
monosaccharide metabolic processGO:00059961060.015
Human
protein modification by small protein conjugationGO:00324461870.015
regulation of cellular response to stressGO:00801351590.015
response to organonitrogen compoundGO:00102432460.015
protein ubiquitinationGO:00165671710.015
lymphocyte differentiationGO:00300982420.015
regulation of intracellular transportGO:00323861590.015
substantia nigra developmentGO:002176220.015
positive regulation of cell deathGO:00109422240.015
positive regulation of programmed cell deathGO:00430682180.015
protein processingGO:00164851630.014
regulation of anatomical structure sizeGO:00900661780.014
membrane lipid biosynthetic processGO:0046467320.014
hexose catabolic processGO:001932030.014
rho protein signal transductionGO:0007266320.014
insulin secretionGO:0030073890.014
neuron deathGO:00709971540.014
g protein coupled receptor signaling pathwayGO:00071862430.014
cilium assemblyGO:0042384810.014
regulation of vesicle mediated transportGO:00606271390.014
lymphocyte proliferationGO:00466511640.014
peptide secretionGO:00027901140.014
regulation of system processGO:00440572000.014
asymmetric neuroblast divisionGO:005505910.014
gtp metabolic processGO:00460391440.014
skeletal muscle organ developmentGO:00605381630.014
gland developmentGO:00487323300.014
canonical wnt signaling pathwayGO:00600701300.013
pentose phosphate shuntGO:000609820.013
regulation of ras protein signal transductionGO:00465781140.013
regulation of centriole replicationGO:004659910.013
response to oxygen levelsGO:0070482620.013
Human
rac protein signal transductionGO:0016601130.013
regulation of homeostatic processGO:00328441820.013
cellular response to oxidative stressGO:0034599760.013
actin cytoskeleton organizationGO:00300362200.013
blood circulationGO:00080151950.013
ameboidal type cell migrationGO:00016671280.013
cellular ion homeostasisGO:00068731650.013
cellular response to organic cyclic compoundGO:0071407870.013
skin developmentGO:00435882200.013
muscle tissue developmentGO:00605373080.013
positive regulation of mitotic cell cycleGO:0045931410.013
cellular protein complex assemblyGO:00436231160.013
regulation of neuron deathGO:19012141340.013
negative regulation of cellular amine metabolic processGO:003323910.013
regulation of establishment of protein localizationGO:00702011810.013
skeletal system developmentGO:00015013560.013
regulation of protein serine threonine kinase activityGO:00719001570.013
response to radiationGO:00093141650.013
apoptotic mitochondrial changesGO:0008637480.013
hematopoietic progenitor cell differentiationGO:00022441430.013
nucleotide biosynthetic processGO:0009165780.013
myeloid cell differentiationGO:00300992330.013
organic acid transportGO:00158491010.012
extracellular structure organizationGO:00430621480.012
regulation of protein catabolic processGO:00421761080.012
epidermis developmentGO:00085441870.012
fertilizationGO:00095661270.012
modification dependent macromolecule catabolic processGO:00436321330.012
hexose metabolic processGO:0019318980.012
Human
engulfment of apoptotic cellGO:004365230.012
ribose phosphate biosynthetic processGO:0046390590.012
cytokine productionGO:00018163190.012
erythrocyte differentiationGO:0030218880.012
regulation of cell activationGO:00508652890.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
digestive system developmentGO:00551232000.012
nucleoside phosphate biosynthetic processGO:1901293790.012
regulation of protein maturationGO:1903317960.012
fatty acid metabolic processGO:00066311210.012
Human Mouse
microtubule based movementGO:0007018840.012
neural precursor cell proliferationGO:00613511210.012
alcohol metabolic processGO:00060661160.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
intra golgi vesicle mediated transportGO:000689110.012
protein depolymerizationGO:0051261340.012
regulation of membrane potentialGO:00423911920.012
purine nucleoside monophosphate metabolic processGO:0009126810.011
protein secretionGO:00093061110.011
extracellular matrix organizationGO:00301981470.011
cellular response to organonitrogen compoundGO:00714171450.011
meiotic cell cycle processGO:1903046770.011
response to organic cyclic compoundGO:00140701980.011
chemotaxisGO:00069352470.011
ubiquitin dependent protein catabolic processGO:00065111290.011
t cell activationGO:00421102890.011
positive regulation of secretionGO:00510471300.011
neuron apoptotic processGO:00514021420.011
myeloid cell homeostasisGO:00022621140.011
negative regulation of cell developmentGO:00107211690.011
gonad developmentGO:00084061410.011
positive regulation of cellular component biogenesisGO:0044089940.011
i kappab kinase nf kappab signalingGO:0007249850.011
endomembrane system organizationGO:00102561470.011
regulation of microtubule cytoskeleton organizationGO:0070507370.011
developmental maturationGO:00217001930.011
positive regulation of protein catabolic processGO:0045732600.011
chromatin organizationGO:00063252060.011
regulation of actin filament based processGO:0032970990.011
microtubule cytoskeleton organization involved in mitosisGO:190285040.011
divalent metal ion transportGO:00708381720.011
circulatory system processGO:00030131970.011
sequestering of calcium ionGO:0051208180.011
positive regulation of intracellular transportGO:0032388700.011
synapsisGO:0007129340.011
carboxylic acid biosynthetic processGO:0046394860.011
regulation of protein kinase activityGO:00458592320.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
positive regulation of kinase activityGO:00336741550.011
cellular protein complex disassemblyGO:0043624360.011
establishment or maintenance of cytoskeleton polarityGO:003095220.011
response to acid chemicalGO:00011011110.011
Human
regulation of multi organism processGO:00439001110.011
positive regulation of protein transportGO:0051222930.011
spindle assembly involved in mitosisGO:009030740.010
transmission of nerve impulseGO:0019226760.010
proteasomal protein catabolic processGO:0010498980.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
regulation of lymphocyte activationGO:00512492400.010
centromere complex assemblyGO:003450830.010
positive regulation of cell developmentGO:00107202370.010
regulation of mitotic cell cycle phase transitionGO:1901990730.010
response to light stimulusGO:00094161350.010
carbohydrate biosynthetic processGO:0016051740.010
reactive oxygen species metabolic processGO:0072593840.010
Human
oxidoreduction coenzyme metabolic processGO:0006733160.010
divalent inorganic cation transportGO:00725111780.010
chromosome organization involved in meiosisGO:0070192390.010
negative regulation of wnt signaling pathwayGO:0030178730.010
regulation of ossificationGO:00302781120.010
muscle system processGO:00030121410.010
regulation of cytokine productionGO:00018172660.010
nicotinamide nucleotide metabolic processGO:0046496120.010
negative regulation of cell proliferationGO:00082852960.010
positive regulation of secretion by cellGO:19035321140.010
regulation of cell divisionGO:0051302760.010
sequestering of metal ionGO:0051238190.010
organism emergence from protective structureGO:007168440.010
leukocyte proliferationGO:00706611720.010
positive regulation of nervous system developmentGO:00519622210.010
modification dependent protein catabolic processGO:00199411330.010
fat cell differentiationGO:00454441600.010

Pdk3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015
nervous system diseaseDOID:86300.015
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011
sensory system diseaseDOID:005015500.011
immune system diseaseDOID:291400.010