IMP: Integrative Multi-species Prediction

Mus musculus

55 known processes

Hif3a

hypoxia inducible factor 3, alpha subunit

(Aliases: bHLHe17,MOP7,NEPAS,Ipas)

Entrez: 53417
Ensembl: ENSMUSG00000004328
UniProtKB: Q0VBL6
UniProtKB: E9Q6J3

Process Predictions
Disease Predictions

Hif3a biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
stem cell development	GO:0048864	219	0.853	Mouse
cellular amine metabolic process	GO:0044106	44	0.846
gland development	GO:0048732	330	0.827	Mouse
blood vessel morphogenesis	GO:0048514	285	0.817	Mouse
regulation of body fluid levels	GO:0050878	162	0.791	Mouse
cardiac muscle tissue development	GO:0048738	130	0.781
forebrain development	GO:0030900	302	0.775	Mouse
angiogenesis	GO:0001525	201	0.766	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.764
muscle cell differentiation	GO:0042692	261	0.705	Mouse
neuronal action potential	GO:0019228	54	0.704
gonad development	GO:0008406	141	0.676
axonogenesis	GO:0007409	274	0.669
central nervous system neuron differentiation	GO:0021953	162	0.628
striated muscle tissue development	GO:0014706	293	0.603
cellular amino acid metabolic process	GO:0006520	103	0.603
muscle tissue development	GO:0060537	308	0.574
regulation of cellular amino acid metabolic process	GO:0006521	5	0.523
small gtpase mediated signal transduction	GO:0007264	97	0.514
regulation of neuron differentiation	GO:0045664	281	0.498
homeostasis of number of cells	GO:0048872	210	0.496	Mouse
regulation of cell cycle	GO:0051726	281	0.487	Fly
dendrite development	GO:0016358	115	0.475
locomotory behavior	GO:0007626	195	0.469	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.466
embryonic epithelial tube formation	GO:0001838	130	0.465	Mouse
cellular response to hormone stimulus	GO:0032870	150	0.464	Fly
glial cell differentiation	GO:0010001	131	0.458
apoptotic signaling pathway	GO:0097190	306	0.424
positive regulation of cellular amine metabolic process	GO:0033240	5	0.424
neural crest cell migration	GO:0001755	32	0.423	Mouse
positive regulation of growth	GO:0045927	104	0.413
skeletal system development	GO:0001501	356	0.405	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.399
transmission of nerve impulse	GO:0019226	76	0.398
anatomical structure homeostasis	GO:0060249	145	0.395	Mouse
lung development	GO:0030324	164	0.393	Mouse
negative regulation of protein metabolic process	GO:0051248	282	0.393
neuroblast proliferation	GO:0007405	49	0.390	Mouse
urogenital system development	GO:0001655	261	0.387	Mouse
gliogenesis	GO:0042063	141	0.387
negative regulation of nervous system development	GO:0051961	156	0.386
central nervous system neuron development	GO:0021954	67	0.384
nucleotide metabolic process	GO:0009117	332	0.380
cell fate commitment	GO:0045165	210	0.374	Mouse
neuron death	GO:0070997	154	0.370	Mouse
neuron migration	GO:0001764	122	0.364
skin development	GO:0043588	220	0.363
cardiocyte differentiation	GO:0035051	87	0.361
regulation of cellular ketone metabolic process	GO:0010565	66	0.360
morphogenesis of a branching epithelium	GO:0061138	193	0.355
camera type eye development	GO:0043010	266	0.355	Mouse
development of primary female sexual characteristics	GO:0046545	73	0.354
neuron projection guidance	GO:0097485	141	0.350
organonitrogen compound catabolic process	GO:1901565	264	0.349
respiratory tube development	GO:0030323	167	0.348	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	352	0.338
cell type specific apoptotic process	GO:0097285	268	0.338	Mouse
myeloid cell homeostasis	GO:0002262	114	0.337	Mouse
regulation of membrane potential	GO:0042391	192	0.337
aortic valve morphogenesis	GO:0003180	4	0.327
cardiac chamber morphogenesis	GO:0003206	93	0.321	Mouse
neural tube formation	GO:0001841	108	0.311	Mouse
hindbrain development	GO:0030902	128	0.311
epidermis development	GO:0008544	187	0.309
neural crest cell development	GO:0014032	48	0.306	Mouse
cardiac ventricle morphogenesis	GO:0003208	50	0.305	Mouse
negative regulation of neuron death	GO:1901215	98	0.303	Mouse
leukocyte differentiation	GO:0002521	342	0.299
purine containing compound metabolic process	GO:0072521	311	0.297
diencephalon development	GO:0021536	63	0.296
ion transmembrane transport	GO:0034220	361	0.295
metencephalon development	GO:0022037	89	0.293
rhythmic process	GO:0048511	174	0.292
stem cell differentiation	GO:0048863	268	0.290	Mouse
ribose phosphate metabolic process	GO:0019693	291	0.289
amine metabolic process	GO:0009308	45	0.279
heart contraction	GO:0060047	93	0.279	Mouse
erythrocyte differentiation	GO:0030218	88	0.278	Mouse
embryonic organ morphogenesis	GO:0048562	276	0.276	Mouse
ensheathment of neurons	GO:0007272	76	0.274
metal ion homeostasis	GO:0055065	189	0.271	Mouse
digestive system development	GO:0055123	200	0.271	Mouse
negative regulation of molecular function	GO:0044092	258	0.270
regulation of neuron projection development	GO:0010975	169	0.268
telencephalon cell migration	GO:0022029	55	0.267
negative regulation of cellular protein metabolic process	GO:0032269	247	0.266
regulation of neural precursor cell proliferation	GO:2000177	70	0.266	Mouse
extracellular structure organization	GO:0043062	148	0.265
cellular chemical homeostasis	GO:0055082	215	0.260	Mouse
axon ensheathment	GO:0008366	76	0.256
regulation of heart contraction	GO:0008016	77	0.256	Mouse
cerebral cortex development	GO:0021987	86	0.256	Mouse
negative regulation of neuron projection development	GO:0010977	50	0.251
cation transport	GO:0006812	399	0.249
ribonucleotide catabolic process	GO:0009261	208	0.239
retina development in camera type eye	GO:0060041	119	0.236	Mouse
ameboidal type cell migration	GO:0001667	128	0.236	Mouse
placenta development	GO:0001890	140	0.235	Mouse
cardiac muscle tissue morphogenesis	GO:0055008	44	0.233
epithelial tube morphogenesis	GO:0060562	303	0.232	Mouse
stem cell proliferation	GO:0072089	117	0.231	Mouse
cytokine production	GO:0001816	319	0.231
connective tissue development	GO:0061448	179	0.231	Mouse
b cell activation	GO:0042113	161	0.230
cell maturation	GO:0048469	127	0.228	Mouse
primary neural tube formation	GO:0014020	95	0.228	Mouse
development of primary sexual characteristics	GO:0045137	143	0.228
tissue remodeling	GO:0048771	102	0.227	Mouse
cellular ketone metabolic process	GO:0042180	84	0.222
developmental maturation	GO:0021700	193	0.221	Mouse
cell adhesion	GO:0007155	329	0.221
astrocyte fate commitment	GO:0060018	4	0.220
regionalization	GO:0003002	337	0.220
cardiac ventricle development	GO:0003231	83	0.219	Mouse
cellular response to peptide	GO:1901653	92	0.212	Fly
regulation of organ morphogenesis	GO:2000027	144	0.212
axon guidance	GO:0007411	141	0.211
blood circulation	GO:0008015	195	0.210	Mouse
respiratory system development	GO:0060541	190	0.210	Mouse Fly
peptidyl amino acid modification	GO:0018193	336	0.208
cardiac chamber development	GO:0003205	108	0.204	Mouse
cellular response to organonitrogen compound	GO:0071417	145	0.200	Fly
glycosyl compound catabolic process	GO:1901658	206	0.200
negative regulation of cell proliferation	GO:0008285	296	0.199
forebrain generation of neurons	GO:0021872	63	0.198
fat cell differentiation	GO:0045444	160	0.197
endocrine system development	GO:0035270	98	0.196
mitral valve development	GO:0003174	4	0.195
regulation of organelle organization	GO:0033043	289	0.193
action potential	GO:0001508	78	0.193
positive regulation of apoptotic process	GO:0043065	217	0.193
sensory organ morphogenesis	GO:0090596	242	0.191
regulation of cell projection organization	GO:0031344	206	0.190
negative regulation of cellular component organization	GO:0051129	194	0.190
positive regulation of homeostatic process	GO:0032846	64	0.188	Mouse
muscle system process	GO:0003012	141	0.188
purine ribonucleotide metabolic process	GO:0009150	290	0.188
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.187	Mouse
morphogenesis of a branching structure	GO:0001763	203	0.186
cell differentiation in hindbrain	GO:0021533	24	0.186
purine ribonucleoside catabolic process	GO:0046130	205	0.185
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.182
embryonic placenta development	GO:0001892	98	0.180	Mouse
epithelial cell proliferation	GO:0050673	174	0.179
positive regulation of cell cycle	GO:0045787	92	0.178
inner ear morphogenesis	GO:0042472	101	0.177
purine nucleotide catabolic process	GO:0006195	211	0.176
cardiac epithelial to mesenchymal transition	GO:0060317	18	0.175
peptidyl tyrosine modification	GO:0018212	145	0.173
positive regulation of angiogenesis	GO:0045766	46	0.169
ribonucleoside catabolic process	GO:0042454	206	0.166
regulation of neuron death	GO:1901214	134	0.165	Mouse
regulation of secretion	GO:0051046	274	0.164	Mouse
regulation of nucleotide metabolic process	GO:0006140	169	0.164
regulation of hydrolase activity	GO:0051336	246	0.163
b cell differentiation	GO:0030183	78	0.163
epithelial cell migration	GO:0010631	63	0.162	Mouse
glial cell development	GO:0021782	54	0.161
sympathetic nervous system development	GO:0048485	22	0.161
positive regulation of ion transport	GO:0043270	65	0.160
neural crest cell differentiation	GO:0014033	54	0.158	Mouse
sensory perception	GO:0007600	245	0.158	Mouse
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.158
glycosyl compound metabolic process	GO:1901657	246	0.157
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.156	Mouse
renal system development	GO:0072001	225	0.152	Mouse
morphogenesis of embryonic epithelium	GO:0016331	159	0.151	Mouse
calcium ion transport	GO:0006816	159	0.150
embryonic skeletal system morphogenesis	GO:0048704	91	0.150
circadian rhythm	GO:0007623	114	0.149
regulation of system process	GO:0044057	200	0.149	Mouse
somitogenesis	GO:0001756	69	0.149
response to decreased oxygen levels	GO:0036293	59	0.148
forebrain neuron differentiation	GO:0021879	52	0.146
cellular homeostasis	GO:0019725	240	0.146	Mouse
ventricular cardiac muscle tissue morphogenesis	GO:0055010	32	0.145
multicellular organismal homeostasis	GO:0048871	164	0.145	Mouse
nerve development	GO:0021675	67	0.145
female sex differentiation	GO:0046660	84	0.144
response to hypoxia	GO:0001666	58	0.143
response to growth factor	GO:0070848	198	0.143	Mouse
intracellular receptor signaling pathway	GO:0030522	74	0.142
regulation of cell migration	GO:0030334	219	0.141	Mouse Fly
tube closure	GO:0060606	91	0.141
divalent inorganic cation homeostasis	GO:0072507	138	0.138
regulation of neural retina development	GO:0061074	3	0.138
muscle cell development	GO:0055001	133	0.137
canonical wnt signaling pathway	GO:0060070	130	0.137
lymphocyte proliferation	GO:0046651	164	0.135
response to peptide	GO:1901652	136	0.134	Fly
negative regulation of protein modification process	GO:0031400	163	0.134
purine containing compound catabolic process	GO:0072523	213	0.133
hair follicle development	GO:0001942	85	0.133
purine ribonucleoside metabolic process	GO:0046128	241	0.132
guanosine containing compound catabolic process	GO:1901069	144	0.131
myotube differentiation	GO:0014902	105	0.130
response to inorganic substance	GO:0010035	96	0.129
purine ribonucleotide catabolic process	GO:0009154	208	0.128
negative regulation of cell projection organization	GO:0031345	56	0.128
nitrogen compound transport	GO:0071705	271	0.126	Mouse
lung epithelial cell differentiation	GO:0060487	29	0.123
branching morphogenesis of an epithelial tube	GO:0048754	159	0.123
neural tube closure	GO:0001843	90	0.122
regulation of endothelial cell migration	GO:0010594	22	0.122
kidney epithelium development	GO:0072073	121	0.122	Mouse
carbohydrate derivative catabolic process	GO:1901136	231	0.121
regulation of ion transport	GO:0043269	215	0.121
purine nucleotide metabolic process	GO:0006163	302	0.120
forebrain cell migration	GO:0021885	58	0.119
positive regulation of cellular catabolic process	GO:0031331	148	0.119	Fly
epithelial cell development	GO:0002064	159	0.118	Mouse
mesenchymal cell development	GO:0014031	93	0.118	Mouse
ovulation cycle	GO:0042698	59	0.118
neural precursor cell proliferation	GO:0061351	121	0.117	Mouse
response to light stimulus	GO:0009416	135	0.117	Mouse
hair cycle	GO:0042633	90	0.116
response to oxygen levels	GO:0070482	62	0.116
neural tube development	GO:0021915	160	0.115	Mouse
carbohydrate homeostasis	GO:0033500	128	0.115	Mouse
negative regulation of neuron differentiation	GO:0045665	101	0.115
glandular epithelial cell differentiation	GO:0002067	38	0.115
wnt signaling pathway	GO:0016055	188	0.114
peptidyl tyrosine phosphorylation	GO:0018108	143	0.114
lung cell differentiation	GO:0060479	30	0.114
stem cell maintenance	GO:0019827	130	0.114
respiratory gaseous exchange	GO:0007585	43	0.113
t cell activation	GO:0042110	289	0.113
cellular response to inorganic substance	GO:0071241	37	0.112
regulation of anatomical structure size	GO:0090066	178	0.111
endothelial cell migration	GO:0043542	44	0.111
epithelial tube formation	GO:0072175	130	0.110	Mouse
alpha beta t cell activation	GO:0046631	91	0.110
bmp signaling pathway	GO:0030509	93	0.110
response to radiation	GO:0009314	165	0.110	Mouse
striated muscle cell development	GO:0055002	125	0.109
sensory perception of mechanical stimulus	GO:0050954	107	0.109
regulation of neuron apoptotic process	GO:0043523	122	0.109	Mouse
transmembrane transport	GO:0055085	412	0.108
regulation of blood circulation	GO:1903522	93	0.107	Mouse
regulation of ossification	GO:0030278	112	0.107	Mouse
germ cell development	GO:0007281	185	0.105	Fly
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.105
multi organism behavior	GO:0051705	62	0.104	Mouse
negative regulation of cell development	GO:0010721	169	0.104
leukocyte proliferation	GO:0070661	172	0.104
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.103
neuromuscular process	GO:0050905	99	0.103	Mouse
subpallium neuron fate commitment	GO:0060163	2	0.103
oligodendrocyte differentiation	GO:0048709	53	0.102
lymphocyte differentiation	GO:0030098	242	0.101
multicellular organismal signaling	GO:0035637	91	0.101
nucleoside phosphate metabolic process	GO:0006753	338	0.101
artery development	GO:0060840	53	0.101
organic cyclic compound catabolic process	GO:1901361	295	0.100
positive regulation of programmed cell death	GO:0043068	218	0.100
embryonic skeletal system development	GO:0048706	120	0.099
synaptic transmission	GO:0007268	329	0.098
regulation of cell motility	GO:2000145	236	0.098	Mouse Fly
positive regulation of cell death	GO:0010942	224	0.097
regulation of epithelial cell migration	GO:0010632	35	0.097	Mouse
positive regulation of nervous system development	GO:0051962	221	0.096	Mouse
limb development	GO:0060173	166	0.095
positive regulation of kidney development	GO:0090184	28	0.095
purine nucleoside catabolic process	GO:0006152	205	0.095
keratinocyte proliferation	GO:0043616	21	0.093
ribonucleoside metabolic process	GO:0009119	245	0.092
heart morphogenesis	GO:0003007	178	0.092	Mouse
myeloid cell differentiation	GO:0030099	233	0.092	Mouse
epithelium migration	GO:0090132	63	0.091	Mouse
molting cycle	GO:0042303	90	0.091
ribonucleotide metabolic process	GO:0009259	291	0.090
tissue migration	GO:0090130	68	0.090	Mouse
asymmetric stem cell division	GO:0098722	3	0.090
regulation of proteolysis	GO:0030162	164	0.089
blastocyst development	GO:0001824	80	0.089
regulation of nucleoside metabolic process	GO:0009118	130	0.089
aromatic compound catabolic process	GO:0019439	286	0.089
organophosphate catabolic process	GO:0046434	232	0.088
positive regulation of cell activation	GO:0050867	158	0.088
lactation	GO:0007595	25	0.088	Mouse
cell division	GO:0051301	120	0.088
ras protein signal transduction	GO:0007265	77	0.087
nephron tubule morphogenesis	GO:0072078	68	0.087
cation homeostasis	GO:0055080	212	0.087	Mouse
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.086
retina morphogenesis in camera type eye	GO:0060042	45	0.086
nephron development	GO:0072006	109	0.086
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.086
regulation of gliogenesis	GO:0014013	50	0.085
paraxial mesodermal cell fate commitment	GO:0048343	2	0.085
regulation of stem cell proliferation	GO:0072091	78	0.085	Mouse
lipid transport	GO:0006869	98	0.084
cation transmembrane transport	GO:0098655	266	0.084
body fluid secretion	GO:0007589	53	0.084	Mouse
limb morphogenesis	GO:0035108	149	0.084
intestinal epithelial cell differentiation	GO:0060575	14	0.083	Mouse
guanosine containing compound metabolic process	GO:1901068	144	0.083
t cell differentiation in thymus	GO:0033077	77	0.083
regulation of cellular catabolic process	GO:0031329	242	0.083	Mouse Fly
regulation of epithelial cell proliferation	GO:0050678	141	0.082
regulation of nuclear division	GO:0051783	56	0.082
erythrocyte maturation	GO:0043249	6	0.082
olfactory bulb interneuron differentiation	GO:0021889	12	0.082
regulation of leukocyte proliferation	GO:0070663	121	0.082
t cell proliferation	GO:0042098	120	0.081
nucleoside phosphate catabolic process	GO:1901292	222	0.081
tube formation	GO:0035148	140	0.080	Mouse
regulation of fat cell differentiation	GO:0045598	81	0.080
outflow tract morphogenesis	GO:0003151	53	0.080	Mouse
actin cytoskeleton organization	GO:0030036	220	0.079
telencephalon development	GO:0021537	186	0.079	Mouse
morphogenesis of a polarized epithelium	GO:0001738	37	0.079
cell differentiation in spinal cord	GO:0021515	53	0.078
g protein coupled receptor signaling pathway	GO:0007186	243	0.078
compound eye development	GO:0048749	1	0.078
lung epithelium development	GO:0060428	37	0.078
endocardial cushion to mesenchymal transition involved in heart valve formation	GO:0003199	4	0.078
regulation of homeostatic process	GO:0032844	182	0.077	Mouse
organic anion transport	GO:0015711	137	0.076
positive regulation of neural precursor cell proliferation	GO:2000179	42	0.076	Mouse
skeletal muscle cell differentiation	GO:0035914	66	0.076
glucose homeostasis	GO:0042593	128	0.076	Mouse
regulation of striated muscle cell differentiation	GO:0051153	81	0.075
mesenchymal cell differentiation	GO:0048762	107	0.075	Mouse
cellular response to monosaccharide stimulus	GO:0071326	47	0.075	Mouse
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.073
regulation of nucleotide catabolic process	GO:0030811	122	0.073
neuron apoptotic process	GO:0051402	142	0.073	Mouse
regulation of actin filament based process	GO:0032970	99	0.073
mitral valve morphogenesis	GO:0003183	4	0.073
nucleoside catabolic process	GO:0009164	206	0.072
organic acid transport	GO:0015849	101	0.072
jak stat cascade	GO:0007259	42	0.071
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.071
regulation of angiogenesis	GO:0045765	81	0.071
developmental programmed cell death	GO:0010623	41	0.071
regulation of transferase activity	GO:0051338	263	0.070
regulation of glial cell differentiation	GO:0045685	41	0.070
cell differentiation involved in kidney development	GO:0061005	33	0.070
nucleotide catabolic process	GO:0009166	217	0.070
digestive tract morphogenesis	GO:0048546	147	0.070	Mouse
cellular response to metal ion	GO:0071248	31	0.070
pancreas development	GO:0031016	57	0.070
positive regulation of proteolysis	GO:0045862	85	0.069
regulation of cell cycle process	GO:0010564	160	0.069
establishment or maintenance of cell polarity	GO:0007163	86	0.069
nucleoside triphosphate catabolic process	GO:0009143	205	0.069
cartilage development	GO:0051216	140	0.069	Mouse
response to organic cyclic compound	GO:0014070	198	0.069
auditory receptor cell fate determination	GO:0042668	3	0.068
regulation of metal ion transport	GO:0010959	106	0.068
digestive tract development	GO:0048565	190	0.068	Mouse
circulatory system process	GO:0003013	197	0.068	Mouse
chromatin modification	GO:0016568	187	0.068
respiratory system process	GO:0003016	25	0.067
kidney development	GO:0001822	213	0.067	Mouse
somite development	GO:0061053	81	0.067
determination of heart left right asymmetry	GO:0061371	48	0.066	Mouse
purine nucleoside metabolic process	GO:0042278	241	0.066
regulation of erythrocyte differentiation	GO:0045646	23	0.066	Mouse
eye photoreceptor cell differentiation	GO:0001754	41	0.066
transdifferentiation	GO:0060290	1	0.066
autonomic nervous system development	GO:0048483	43	0.066
multicellular organism growth	GO:0035264	161	0.065
cerebral cortex cell migration	GO:0021795	44	0.065
developmental cell growth	GO:0048588	84	0.065
olfactory bulb development	GO:0021772	30	0.064
cervix development	GO:0060067	2	0.064
endocytosis	GO:0006897	168	0.064
lung alveolus development	GO:0048286	45	0.064
protein catabolic process	GO:0030163	221	0.064
positive regulation of inner ear receptor cell differentiation	GO:2000982	1	0.064
negative regulation of cellular amine metabolic process	GO:0033239	1	0.063
cellular calcium ion homeostasis	GO:0006874	119	0.063
inflammatory response	GO:0006954	244	0.063	Mouse
response to peptide hormone	GO:0043434	127	0.062	Fly
protein modification by small protein conjugation	GO:0032446	187	0.062
regulation of mitotic cell cycle	GO:0007346	126	0.062
response to organonitrogen compound	GO:0010243	246	0.062	Fly
synapse organization	GO:0050808	125	0.062
cerebellum morphogenesis	GO:0021587	42	0.062
protein processing	GO:0016485	163	0.061
muscle tissue morphogenesis	GO:0060415	53	0.061
reactive oxygen species metabolic process	GO:0072593	84	0.061
cellular response to dna damage stimulus	GO:0006974	207	0.061	Fly
regulation of cell adhesion	GO:0030155	154	0.061
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.060
calcium ion transmembrane transport	GO:0070588	85	0.060
protein acylation	GO:0043543	64	0.060
macromolecule catabolic process	GO:0009057	281	0.060
positive regulation of keratinocyte proliferation	GO:0010838	4	0.060
negative regulation of cell motility	GO:2000146	61	0.060
midbrain development	GO:0030901	35	0.060
chemotaxis	GO:0006935	247	0.060
regulation of cell activation	GO:0050865	289	0.060
organonitrogen compound biosynthetic process	GO:1901566	192	0.060
divalent metal ion transport	GO:0070838	172	0.059
negative regulation of phosphorylation	GO:0042326	166	0.059
response to insulin	GO:0032868	100	0.059	Fly
apoptotic process involved in morphogenesis	GO:0060561	25	0.059
regulation of apoptotic signaling pathway	GO:2001233	197	0.059
regulation of lymphocyte apoptotic process	GO:0070228	41	0.059	Mouse
ventricular cardiac muscle tissue development	GO:0003229	38	0.059
ovarian follicle development	GO:0001541	40	0.059
regulation of vasculature development	GO:1901342	88	0.059
pancreatic pp cell fate commitment	GO:0003329	2	0.058
asymmetric neuroblast division	GO:0055059	1	0.058
regulation of mapk cascade	GO:0043408	248	0.058
dorsal ventral axon guidance	GO:0033563	3	0.058
lymphocyte homeostasis	GO:0002260	64	0.058	Mouse
cognition	GO:0050890	149	0.057	Mouse
positive regulation of protein modification process	GO:0031401	299	0.057
pallium development	GO:0021543	120	0.057	Mouse
learning or memory	GO:0007611	148	0.057	Mouse
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.056
mitotic cell cycle	GO:0000278	195	0.056
intestinal epithelial cell development	GO:0060576	12	0.056	Mouse
positive regulation of cell migration	GO:0030335	109	0.056	Mouse
carbohydrate derivative biosynthetic process	GO:1901137	183	0.056
regulation of secretion by cell	GO:1903530	249	0.056	Mouse
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process	GO:2000763	1	0.055
negative regulation of cell migration	GO:0030336	59	0.054
extracellular matrix organization	GO:0030198	147	0.054
cellular nitrogen compound catabolic process	GO:0044270	280	0.054
cellular response to external stimulus	GO:0071496	88	0.054	Worm
catecholamine metabolic process	GO:0006584	30	0.054	Mouse
lipid localization	GO:0010876	126	0.054
regulation of protein serine threonine kinase activity	GO:0071900	157	0.054
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.053
nucleoside triphosphate metabolic process	GO:0009141	230	0.053
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.053
regulation of dna binding	GO:0051101	39	0.053
regulation of cell division	GO:0051302	76	0.053
cranial nerve development	GO:0021545	41	0.053
ureteric bud morphogenesis	GO:0060675	62	0.053
hematopoietic progenitor cell differentiation	GO:0002244	143	0.053
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.053
protein modification by small protein conjugation or removal	GO:0070647	207	0.052
regulation of circadian rhythm	GO:0042752	58	0.052
nucleoside metabolic process	GO:0009116	246	0.052
cell fate determination involved in pattern specification	GO:0060582	1	0.052
positive regulation of map kinase activity	GO:0043406	84	0.052
columnar cuboidal epithelial cell development	GO:0002066	29	0.052	Mouse
negative regulation of phosphate metabolic process	GO:0045936	184	0.052
cell growth	GO:0016049	130	0.052	Fly
semaphorin plexin signaling pathway	GO:0071526	21	0.051
anion transport	GO:0006820	177	0.051
cardiac muscle contraction	GO:0060048	32	0.051
regulation of jak stat cascade	GO:0046425	34	0.051
b cell proliferation	GO:0042100	53	0.051
cellular response to abiotic stimulus	GO:0071214	56	0.051
regulation of glucose metabolic process	GO:0010906	60	0.051
positive regulation of behavior	GO:0048520	40	0.051
regeneration	GO:0031099	38	0.051
maintenance of location	GO:0051235	89	0.051
regulation of response to wounding	GO:1903034	189	0.050
heterocycle catabolic process	GO:0046700	280	0.050
positive regulation of synaptic plasticity	GO:0031915	4	0.050
peripheral nervous system development	GO:0007422	53	0.050
spermatogenesis	GO:0007283	284	0.050
female gonad development	GO:0008585	71	0.050
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	GO:0072108	3	0.050
protein ubiquitination	GO:0016567	171	0.050
cellular metal ion homeostasis	GO:0006875	151	0.050	Mouse
neuron projection extension	GO:1990138	64	0.050
regulation of transmembrane transport	GO:0034762	128	0.049
hypothalamus development	GO:0021854	16	0.049
cell proliferation involved in outflow tract morphogenesis	GO:0061325	4	0.049
cellular response to peptide hormone stimulus	GO:0071375	92	0.049	Fly
membrane organization	GO:0061024	245	0.049
sensory system development	GO:0048880	3	0.049
positive regulation of response to wounding	GO:1903036	66	0.049
histone modification	GO:0016570	159	0.049
positive regulation of organelle organization	GO:0010638	128	0.048
glossopharyngeal nerve morphogenesis	GO:0021615	4	0.048
positive regulation of auditory receptor cell differentiation	GO:0045609	1	0.048
endocrine pancreas development	GO:0031018	29	0.048
positive regulation of transmembrane transport	GO:0034764	29	0.048
cerebellum development	GO:0021549	77	0.048
oligodendrocyte development	GO:0014003	20	0.047
divalent inorganic cation transport	GO:0072511	178	0.047
regulation of mast cell differentiation	GO:0060375	3	0.047
body morphogenesis	GO:0010171	45	0.047
epithelial to mesenchymal transition	GO:0001837	47	0.047	Mouse
regulation of lipid transport	GO:0032368	36	0.047
organelle fission	GO:0048285	170	0.047
male gamete generation	GO:0048232	285	0.047
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	40	0.047
regulation of lymphocyte proliferation	GO:0050670	117	0.047
cellular response to insulin stimulus	GO:0032869	78	0.047	Fly
heart process	GO:0003015	94	0.046	Mouse
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.046
positive regulation of gliogenesis	GO:0014015	27	0.046
carbohydrate metabolic process	GO:0005975	230	0.046	Mouse
intracellular protein transport	GO:0006886	204	0.046

Hif3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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