Mus musculus

97 known processes

Tbk1

TANK-binding kinase 1

(Aliases: AW048562,MGC150302,1200008B05Rik,MGC150301,AI462036)

Tbk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dendritic cell proliferationGO:004456520.823
i kappab kinase nf kappab signalingGO:0007249850.732
Human Mouse
leukocyte proliferationGO:00706611720.535
purine nucleoside triphosphate catabolic processGO:00091462030.461
cytokine productionGO:00018163190.389
nucleoside phosphate metabolic processGO:00067533380.379
inflammatory responseGO:00069542440.335
positive regulation of cytokine productionGO:00018191740.324
activation of immune responseGO:00022531380.321
nucleoside triphosphate metabolic processGO:00091412300.296
epithelial tube formationGO:00721751300.264
organic cyclic compound catabolic processGO:19013612950.259
t cell activationGO:00421102890.256
response to organonitrogen compoundGO:00102432460.246
regulation of neuron differentiationGO:00456642810.243
neutrophil degranulationGO:004331260.231
regulation of innate immune responseGO:0045088910.230
regulation of lymphocyte activationGO:00512492400.226
nucleoside triphosphate catabolic processGO:00091432050.216
antibacterial peptide productionGO:000277820.212
purine nucleoside metabolic processGO:00422782410.210
immune response activating signal transductionGO:00027571160.208
vesicle organizationGO:0016050600.203
neuron apoptotic processGO:00514021420.201
ribonucleoside triphosphate metabolic processGO:00091992200.191
cell type specific apoptotic processGO:00972852680.189
morphogenesis of embryonic epitheliumGO:00163311590.182
purine nucleotide catabolic processGO:00061952110.181
protein modification by small protein conjugationGO:00324461870.171
positive regulation of secretionGO:00510471300.171
purine containing compound metabolic processGO:00725213110.157
embryonic epithelial tube formationGO:00018381300.154
axonogenesisGO:00074092740.150
nucleobase containing small molecule metabolic processGO:00550863520.143
regulation of sequence specific dna binding transcription factor activityGO:00510901060.137
positive regulation of cell deathGO:00109422240.135
Fly
negative regulation of t cell activationGO:0050868650.134
immune response regulating signaling pathwayGO:00027641250.133
peptidyl amino acid modificationGO:00181933360.132
Fly
regulation of cytokine productionGO:00018172660.132
leukocyte differentiationGO:00025213420.128
Mouse
single organismal cell cell adhesionGO:00163371310.128
heart morphogenesisGO:00030071780.127
positive regulation of innate immune responseGO:0045089800.123
pigmentationGO:0043473710.117
immune response in mucosal associated lymphoid tissueGO:000238620.117
response to organic cyclic compoundGO:00140701980.116
lymphocyte proliferationGO:00466511640.116
response to peptideGO:19016521360.116
regulation of synaptic growth at neuromuscular junctionGO:000858240.113
nucleoside monophosphate metabolic processGO:0009123850.113
nucleoside metabolic processGO:00091162460.107
regulation of inflammatory responseGO:00507271470.107
regulation of t cell activationGO:00508631700.105
neural tube developmentGO:00219151600.103
regulation of neuron apoptotic processGO:00435231220.101
nucleoside phosphate catabolic processGO:19012922220.101
activation of innate immune responseGO:0002218560.101
tumor necrosis factor productionGO:0032640500.101
ribonucleoside monophosphate metabolic processGO:0009161800.099
epidermis developmentGO:00085441870.095
negative regulation of calcium ion dependent exocytosisGO:004595530.095
regulation of protein processingGO:0070613960.095
response to peptide hormoneGO:00434341270.094
glycosyl compound metabolic processGO:19016572460.093
cellular response to cytokine stimulusGO:00713451890.093
regulation of cell activationGO:00508652890.092
negative regulation of neuron apoptotic processGO:0043524920.092
regulation of secretionGO:00510462740.092
purine nucleoside triphosphate metabolic processGO:00091442260.092
wound healingGO:00420601570.092
nucleotide metabolic processGO:00091173320.091
heterocycle catabolic processGO:00467002800.090
positive regulation of apoptotic processGO:00430652170.089
Fly
negative regulation of cellular amine metabolic processGO:003323910.088
carbohydrate derivative catabolic processGO:19011362310.086
regulation of secretion by cellGO:19035302490.086
negative regulation of cell proliferationGO:00082852960.085
ribonucleoside metabolic processGO:00091192450.085
positive regulation of hydrolase activityGO:00513451480.083
Fly
hormone secretionGO:00468791280.083
angiogenesisGO:00015252010.083
cellular lipid metabolic processGO:00442553230.083
ribonucleoside catabolic processGO:00424542060.082
response to insulinGO:00328681000.082
cell adhesionGO:00071553290.080
negative regulation of insulin receptor signaling pathwayGO:0046627140.079
positive regulation of growthGO:00459271040.079
aromatic compound catabolic processGO:00194392860.079
regulation of cellular component sizeGO:00325351210.078
neurotransmitter secretionGO:0007269620.078
regulation of cell migrationGO:00303342190.076
neuron deathGO:00709971540.076
regulation of leukocyte differentiationGO:19021051590.076
carbohydrate homeostasisGO:00335001280.076
regulation of endopeptidase activityGO:0052548890.074
Fly
cation transportGO:00068123990.073
Mouse
interleukin 6 productionGO:0032635580.073
myeloid leukocyte activationGO:0002274830.073
positive regulation of cell developmentGO:00107202370.072
regulation of purine nucleotide metabolic processGO:19005421690.069
positive regulation of smooth muscle cell migrationGO:001491140.069
somite specificationGO:000175740.068
regulation of endocytosisGO:0030100690.068
innate immune response activating signal transductionGO:0002758500.066
regulation of nucleoside metabolic processGO:00091181300.066
rho protein signal transductionGO:0007266320.066
positive regulation of defense responseGO:00313491240.065
regulation of insulin receptor signaling pathwayGO:0046626210.065
regulation of t cell differentiationGO:0045580830.065
regionalizationGO:00030023370.063
regulation of cellular ketone metabolic processGO:0010565660.062
protein ubiquitinationGO:00165671710.062
ribose phosphate metabolic processGO:00196932910.062
regulation of ion transmembrane transporter activityGO:0032412540.062
Mouse
regulation of synaptic vesicle transportGO:1902803130.062
regulation of t cell proliferationGO:0042129920.061
cellular nitrogen compound catabolic processGO:00442702800.061
regulation of exocytosisGO:0017157610.060
negative regulation of neuron deathGO:1901215980.059
regulation of antibacterial peptide biosynthetic processGO:000280810.059
tube formationGO:00351481400.058
stem cell differentiationGO:00488632680.058
regulation of protein maturationGO:1903317960.058
exocytosisGO:00068871210.058
regulation of response to woundingGO:19030341890.056
methylationGO:00322591340.056
positive regulation of protein modification processGO:00314012990.056
regulation of nucleotide metabolic processGO:00061401690.055
purine ribonucleoside metabolic processGO:00461282410.055
negative regulation of cellular component organizationGO:00511291940.055
protein processingGO:00164851630.054
regulation of neuron projection developmentGO:00109751690.054
epithelial tube morphogenesisGO:00605623030.054
wnt signaling pathway planar cell polarity pathwayGO:0060071270.053
regulation of organ morphogenesisGO:20000271440.053
peptidyl serine modificationGO:0018209830.053
Fly
cellular amino acid metabolic processGO:00065201030.053
maintenance of locationGO:0051235890.052
regulation of cellular amino acid metabolic processGO:000652150.052
purine nucleotide metabolic processGO:00061633020.052
positive regulation of antimicrobial humoral responseGO:000276020.051
lipid storageGO:0019915360.051
purine ribonucleotide catabolic processGO:00091542080.051
regulation of anatomical structure sizeGO:00900661780.051
cellular amine metabolic processGO:0044106440.050
regulation of defense responseGO:00313472330.050
purine ribonucleoside catabolic processGO:00461302050.050
regulation of reactive oxygen species metabolic processGO:2000377400.050
developmental maturationGO:00217001930.050
Fly
purine ribonucleoside triphosphate metabolic processGO:00092052200.049
regulation of cellular component biogenesisGO:00440871810.049
synaptic vesicle localizationGO:0097479590.049
regulation of cytokine biosynthetic processGO:0042035590.049
regulation of nucleotide catabolic processGO:00308111220.048
striated muscle tissue developmentGO:00147062930.048
cell agingGO:0007569350.048
regulation of body fluid levelsGO:00508781620.048
Mouse
protein modification by small protein conjugation or removalGO:00706472070.048
protein maturationGO:00516041760.047
cellular response to lipopolysaccharideGO:0071222770.047
amine metabolic processGO:0009308450.047
tumor necrosis factor superfamily cytokine productionGO:0071706510.046
positive regulation of cellular amino acid metabolic processGO:004576430.046
purine ribonucleotide metabolic processGO:00091502900.046
purine nucleoside catabolic processGO:00061522050.045
negative regulation of molecular functionGO:00440922580.045
regulation of hydrolase activityGO:00513362460.045
Fly
neural tube formationGO:00018411080.044
regulation of ion transportGO:00432692150.044
Mouse
negative regulation of growthGO:0045926990.043
regulation of cell motilityGO:20001452360.043
response to lipopolysaccharideGO:00324961280.043
establishment or maintenance of cell polarityGO:0007163860.043
reactive oxygen species metabolic processGO:0072593840.042
positive regulation of interferon beta productionGO:003272880.042
synaptic transmissionGO:00072683290.042
fat cell differentiationGO:00454441600.042
cytokine metabolic processGO:0042107710.041
nuclear divisionGO:00002801580.040
nucleoside monophosphate catabolic processGO:0009125590.040
male gamete generationGO:00482322850.040
protein localization to organelleGO:00333651850.040
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.040
Fly
nucleoside catabolic processGO:00091642060.040
positive regulation of nervous system developmentGO:00519622210.040
neurotransmitter transportGO:0006836760.040
negative regulation of hydrolase activityGO:0051346710.039
positive regulation of programmed cell deathGO:00430682180.039
Fly
regulation of interferon beta biosynthetic processGO:004535740.039
hormone mediated signaling pathwayGO:0009755230.038
positive regulation of leukocyte differentiationGO:1902107860.038
single organism cell adhesionGO:00986021560.038
cellular macromolecule catabolic processGO:00442652060.038
cellular response to organonitrogen compoundGO:00714171450.038
respiratory tube developmentGO:00303231670.038
blood vessel morphogenesisGO:00485142850.038
respiratory system developmentGO:00605411900.038
Fly
pigment granule localizationGO:0051875130.037
lipid localizationGO:00108761260.037
positive regulation of cellular catabolic processGO:00313311480.037
peptidyl tyrosine phosphorylationGO:00181081430.037
regulation of production of molecular mediator of immune responseGO:0002700650.037
regulation of cell growthGO:0001558910.036
positive regulation of cytokine biosynthetic processGO:0042108400.036
organophosphate catabolic processGO:00464342320.035
neuronal action potentialGO:0019228540.035
nitrogen compound transportGO:00717052710.035
ribonucleotide catabolic processGO:00092612080.035
positive regulation of lymphocyte activationGO:00512511400.035
regulation of cytoskeleton organizationGO:00514931220.035
Fly
cellular ketone metabolic processGO:0042180840.035
cellular response to biotic stimulusGO:0071216920.035
mammary gland epithelium developmentGO:0061180650.034
Mouse
regulation of cellular response to insulin stimulusGO:1900076300.034
purine ribonucleoside monophosphate metabolic processGO:0009167800.034
regulation of cell projection organizationGO:00313442060.034
immunoglobulin transcytosis in epithelial cellsGO:000241420.034
synaptic vesicle maturationGO:001618870.033
membrane organizationGO:00610242450.033
positive regulation of toll like receptor 4 signaling pathwayGO:003414510.032
negative regulation of immune system processGO:00026832090.032
covalent chromatin modificationGO:00165691630.032
vesicle docking involved in exocytosisGO:000690470.032
proteolysis involved in cellular protein catabolic processGO:00516031470.032
regulation of protein localizationGO:00328802310.032
morphogenesis of a polarized epitheliumGO:0001738370.032
cellular response to molecule of bacterial originGO:0071219830.032
positive regulation of sequestering of triglycerideGO:001089040.032
glycosyl compound catabolic processGO:19016582060.031
spermatogenesisGO:00072832840.031
somitogenesisGO:0001756690.031
interspecies interaction between organismsGO:0044419830.031
homeostasis of number of cellsGO:00488722100.031
Mouse
dna metabolic processGO:00062593030.031
positive regulation of protein phosphorylationGO:00019342420.030
ribonucleotide metabolic processGO:00092592910.030
cellular response to arsenic containing substanceGO:007124340.030
mammary gland epithelial cell proliferationGO:0033598240.030
Mouse
negative regulation of protein maturationGO:1903318790.030
purine nucleoside monophosphate metabolic processGO:0009126810.030
t cell differentiationGO:00302171740.030
small gtpase mediated signal transductionGO:0007264970.029
calcium ion dependent exocytosisGO:0017156350.029
modification dependent macromolecule catabolic processGO:00436321330.029
protein kinase b signalingGO:0043491740.029
regulation of planar cell polarity pathway involved in axis elongationGO:200004030.028
positive regulation of cysteine type endopeptidase activityGO:2001056390.028
Fly
regulation of t cell differentiation in thymusGO:0033081240.028
metal ion homeostasisGO:00550651890.028
synaptic vesicle recyclingGO:0036465190.028
nucleotide catabolic processGO:00091662170.028
protein polymerizationGO:0051258570.028
multi multicellular organism processGO:00447061090.028
regulation of ossificationGO:00302781120.028
mapk cascadeGO:00001652810.028
organelle fusionGO:0048284280.028
positive regulation of cellular amine metabolic processGO:003324050.028
cellular protein catabolic processGO:00442571550.028
cytokine biosynthetic processGO:0042089680.027
antigen receptor mediated signaling pathwayGO:0050851640.027
regulation of platelet derived growth factor receptor beta signaling pathwayGO:200058620.027
regulation of lymphocyte differentiationGO:00456191070.027
action potentialGO:0001508780.027
negative regulation of intracellular signal transductionGO:19025321670.027
positive regulation of antibacterial peptide biosynthetic processGO:000696310.027
regulation of protein transportGO:00512231630.027
organophosphate biosynthetic processGO:00904071220.027
regulated secretory pathwayGO:0045055320.027
regulation of cellular catabolic processGO:00313292420.027
immune effector processGO:00022523210.027
meiotic cell cycleGO:00513211220.026
regulation of neuron deathGO:19012141340.026
regulation of cellular amine metabolic processGO:0033238200.026
endocytosisGO:00068971680.026
extrinsic apoptotic signaling pathwayGO:00971911260.026
regulation of antibacterial peptide productionGO:000278610.026
spermatid differentiationGO:00485151150.026
t cell proliferationGO:00420981200.026
ribonucleoside triphosphate catabolic processGO:00092031990.026
regulation of protein kinase b signalingGO:0051896560.026
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.026
rhythmic processGO:00485111740.026
embryonic organ morphogenesisGO:00485622760.026
negative regulation of lymphocyte activationGO:0051250910.026
negative regulation of cytokine productionGO:0001818840.026
microtubule based processGO:00070172360.025
Fly
modification dependent protein catabolic processGO:00199411330.025
response to nutrient levelsGO:00316671090.025
negative regulation of cell activationGO:00508661110.025
response to oxidative stressGO:00069791230.025
pattern recognition receptor signaling pathwayGO:0002221470.025
epithelial cell developmentGO:00020641590.025
organelle localizationGO:00516401790.025
positive regulation of gtpase activityGO:0043547850.025
establishment of protein localization to organelleGO:00725941180.025
amide transportGO:00428861380.025
organonitrogen compound catabolic processGO:19015652640.024
primary neural tube formationGO:0014020950.024
muscle tissue developmentGO:00605373080.024
negative regulation of proteolysisGO:0045861740.024
non canonical wnt signaling pathwayGO:0035567330.023
peptide secretionGO:00027901140.023
intracellular cholesterol transportGO:003236730.023
regulation of neurotransmitter secretionGO:0046928290.023
muscle cell differentiationGO:00426922610.023
regulation of androgen receptor signaling pathwayGO:006076530.023
notch signaling pathwayGO:0007219710.023
regulation of cell cycleGO:00517262810.023
positive regulation of engulfment of apoptotic cellGO:190107610.023
neural tube closureGO:0001843900.023
cellular response to peptide hormone stimulusGO:0071375920.023
cellular homeostasisGO:00197252400.023
response to molecule of bacterial originGO:00022371430.023
apoptotic signaling pathwayGO:00971903060.022
embryonic appendage morphogenesisGO:00351131260.022
ribonucleoside monophosphate catabolic processGO:0009158570.022
circadian rhythmGO:00076231140.022
negative regulation of protein processingGO:0010955790.022
regulation of cell sizeGO:0008361720.022
organelle fissionGO:00482851700.022
skin developmentGO:00435882200.022
regulation of synaptic transmission gabaergicGO:0032228170.022
regulation of hormone levelsGO:00108172110.022
mitotic cell cycleGO:00002781950.022
negative regulation of endopeptidase activityGO:0010951440.022
digestive system developmentGO:00551232000.022
interferon beta biosynthetic processGO:004535040.021
positive regulation of interleukin 6 productionGO:0032755370.021
neuromuscular synaptic transmissionGO:0007274160.021
regulation of ion transmembrane transportGO:00347651190.021
Mouse
establishment of pigment granule localizationGO:0051905120.021
peptidyl tyrosine modificationGO:00182121450.021
somite developmentGO:0061053810.021
positive regulation of interferon beta biosynthetic processGO:004535930.021
developmental growth involved in morphogenesisGO:00605601380.021
granulocyte activationGO:0036230100.021
t cell differentiation in thymusGO:0033077770.021
cellular response to insulin stimulusGO:0032869780.021
myeloid leukocyte differentiationGO:00025731190.021
Mouse
positive regulation of proteolysisGO:0045862850.021
Fly
macromolecule methylationGO:00434141200.021
regulation of lymphocyte proliferationGO:00506701170.021
cell substrate adhesionGO:00315891300.021
positive regulation of apoptotic signaling pathwayGO:2001235950.021
humoral immune responseGO:0006959570.021
negative regulation of tor signalingGO:0032007130.021
synaptic transmission gabaergicGO:0051932190.021
regulation of intracellular protein transportGO:0033157820.021
cardiac ventricle developmentGO:0003231830.021
phospholipid metabolic processGO:0006644870.020
regulation of purine nucleotide catabolic processGO:00331211220.020
epithelial cell proliferationGO:00506731740.020
Mouse
b cell activationGO:00421131610.020
actin cytoskeleton organizationGO:00300362200.020
Fly
negative regulation of cell developmentGO:00107211690.020
regulation of transferase activityGO:00513382630.020
macromolecule catabolic processGO:00090572810.020
defense response to virusGO:0051607680.020
establishment of protein localization to vacuoleGO:007266640.020
positive regulation of peptidase activityGO:0010952490.020
Fly
negative regulation of inflammatory responseGO:0050728610.020
negative regulation of neuron differentiationGO:00456651010.020
necrotic cell deathGO:0070265300.020
forebrain neuron differentiationGO:0021879520.020
cellular response to hormone stimulusGO:00328701500.020
atp metabolic processGO:0046034750.020
leukocyte mediated immunityGO:00024431740.020
regulation of membrane potentialGO:00423911920.020
establishment of synaptic vesicle localizationGO:0097480570.020
regulation of synaptic vesicle exocytosisGO:2000300110.020
regulation of carbohydrate biosynthetic processGO:0043255400.020
toll like receptor 3 signaling pathwayGO:003413840.020
cellular response to interleukin 15GO:007135020.020
regulation of mapk cascadeGO:00434082480.020
negative regulation of cellular amino acid metabolic processGO:004576300.019
interferon gamma mediated signaling pathwayGO:006033350.019
positive regulation of cell adhesionGO:0045785800.019
cellular response to peptideGO:1901653920.019
insulin secretionGO:0030073890.019
protein localization to endosomeGO:003601020.019
negative regulation of nf kappab transcription factor activityGO:0032088150.019
cellular response to dna damage stimulusGO:00069742070.019
cell maturationGO:00484691270.019
Fly
protein localization to vacuoleGO:007266540.019
syncytium formation by plasma membrane fusionGO:0000768420.019
lymphocyte differentiationGO:00300982420.019
molting cycleGO:0042303900.019
regulation of antimicrobial peptide biosynthetic processGO:000280510.018
cell fate commitmentGO:00451652100.018
development of primary sexual characteristicsGO:00451371430.018
negative regulation of peptidase activityGO:0010466460.018
positive regulation of purine nucleotide catabolic processGO:0033123880.018
chromatin organizationGO:00063252060.018
regulation of metal ion transportGO:00109591060.018
Mouse
cellular response to lipidGO:00713961450.018
locomotory behaviorGO:00076261950.018
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.018
embryonic heart tube developmentGO:0035050650.018
positive regulation of protein kinase b signalingGO:0051897320.018
positive regulation of kinase activityGO:00336741550.018
positive regulation of nucleoside metabolic processGO:0045979910.018
neutrophil mediated immunityGO:0002446190.018
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.018
gland developmentGO:00487323300.018
Mouse
multicellular organismal signalingGO:0035637910.017
interferon gamma productionGO:0032609670.017
gtp catabolic processGO:00061841430.017
cell growthGO:00160491300.017
glucose homeostasisGO:00425931280.017
intracellular sterol transportGO:003236630.017
axon target recognitionGO:000741240.017
regulation of vasculature developmentGO:1901342880.017
antimicrobial peptide productionGO:000277520.017
cardiac chamber developmentGO:00032051080.017
immune response regulating cell surface receptor signaling pathwayGO:0002768800.017
hepatocyte growth factor receptor signaling pathwayGO:004801230.017
negative regulation of cellular carbohydrate metabolic processGO:0010677190.017
guanosine containing compound catabolic processGO:19010691440.017
monoubiquitinated histone h2a deubiquitinationGO:003552210.017
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.017
peptidyl serine phosphorylationGO:0018105740.016
Fly
establishment of tissue polarityGO:0007164280.016
protein catabolic processGO:00301632210.016
regulation of vesicle mediated transportGO:00606271390.016
regulation of cysteine type endopeptidase activityGO:2000116650.016
Fly
atp catabolic processGO:0006200550.016
regulation of interleukin 6 productionGO:0032675550.016
response to tumor necrosis factorGO:0034612260.016
diencephalon developmentGO:0021536630.016
regulation of homeostatic processGO:00328441820.016
divalent inorganic cation homeostasisGO:00725071380.016
cell divisionGO:00513011200.016
Fly
apical constrictionGO:000338340.016
protein retention in golgi apparatusGO:004505310.016
regulation of antimicrobial peptide productionGO:000278410.016
regulation of tor signalingGO:0032006170.016
response to acid chemicalGO:00011011110.016
establishment or maintenance of apical basal cell polarityGO:0035088210.015
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.015
regulation of erk1 and erk2 cascadeGO:0070372710.015
b cell homeostasisGO:0001782340.015
Mouse
protein targetingGO:00066051430.015
actin filament based movementGO:0030048230.015
negative regulation of phosphorylationGO:00423261660.015
regulation of cell morphogenesis involved in differentiationGO:00107691510.015
cellular metal ion homeostasisGO:00068751510.015
cellular protein complex assemblyGO:00436231160.015
wnt signaling pathwayGO:00160551880.015
tissue homeostasisGO:00018941150.015
Fly
positive regulation of nucleotide catabolic processGO:0030813880.015
spermatid developmentGO:00072861080.015
negative regulation of protein metabolic processGO:00512482820.015
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptorGO:000241510.015
canonical wnt signaling pathwayGO:00600701300.015
hematopoietic progenitor cell differentiationGO:00022441430.015
regulation of multi organism processGO:00439001110.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
organic hydroxy compound transportGO:0015850930.014
positive regulation of exocytosisGO:0045921200.014
positive regulation of neuron projection developmentGO:0010976790.014
positive t cell selectionGO:0043368230.014
skeletal system developmentGO:00015013560.014
regulation of organelle organizationGO:00330432890.014
Fly
positive regulation of lipid storageGO:0010884100.014
response to steroid hormoneGO:0048545560.014
interleukin 2 mediated signaling pathwayGO:003811020.014
positive regulation of defense response to virus by hostGO:000223060.014
negative regulation of fatty acid transportGO:200019210.014
positive regulation of purine nucleotide metabolic processGO:19005441140.014
regulation of mitotic cell cycle phase transitionGO:1901990730.014
regulation of proteolysisGO:00301621640.014
Fly
muscle atrophyGO:001488930.014
regulation of establishment of protein localizationGO:00702011810.014
antimicrobial peptide biosynthetic processGO:000277720.014
purine containing compound catabolic processGO:00725232130.014
regulation of leukocyte proliferationGO:00706631210.014
regulation of protein complex assemblyGO:0043254830.014
positive regulation of mapk cascadeGO:00434101700.014
establishment of planar polarityGO:0001736280.014
regulation of gluconeogenesisGO:0006111300.014
determination of heart left right asymmetryGO:0061371480.013
regulation of antimicrobial humoral responseGO:000275930.013
cellular response to oxidative stressGO:0034599760.013
inorganic ion transmembrane transportGO:00986602340.013
negative regulation of cell motilityGO:2000146610.013
lymphocyte homeostasisGO:0002260640.013
Mouse

Tbk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.073
cancerDOID:16200.073
organ system cancerDOID:005068600.036
connective tissue diseaseDOID:6500.019
disease of anatomical entityDOID:700.019
bone diseaseDOID:008000100.019
musculoskeletal system diseaseDOID:1700.019
gastrointestinal system cancerDOID:311900.015
large intestine cancerDOID:567200.015
intestinal cancerDOID:1015500.015
colorectal cancerDOID:925600.015
colon cancerDOID:21900.015