IMP: Integrative Multi-species Prediction

Mus musculus

64 known processes

Foxe1

forkhead box E1

(Aliases: Titf2)

Ensembl: ENSMUSG00000070990
Entrez: 110805
UniProtKB: Q8R2I0

Process Predictions
Disease Predictions

Foxe1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
hyperosmotic salinity response	GO:0042538	1	0.587
heart trabecula formation	GO:0060347	14	0.462
positive regulation of nervous system development	GO:0051962	221	0.358	Mouse
response to molecule of bacterial origin	GO:0002237	143	0.355
calcium ion transmembrane transport	GO:0070588	85	0.340
triglyceride metabolic process	GO:0006641	51	0.311
cell fate commitment	GO:0045165	210	0.291	Mouse
kidney development	GO:0001822	213	0.272	Mouse
cation transmembrane transport	GO:0098655	266	0.265
stem cell development	GO:0048864	219	0.257	Mouse
muscle system process	GO:0003012	141	0.256
regulation of voltage gated calcium channel activity	GO:1901385	4	0.240
clara cell differentiation	GO:0060486	4	0.237
glycerolipid metabolic process	GO:0046486	122	0.234
embryonic organ morphogenesis	GO:0048562	276	0.231
urogenital system development	GO:0001655	261	0.228	Mouse
b cell activation	GO:0042113	161	0.227
ion transmembrane transport	GO:0034220	361	0.223
b cell differentiation	GO:0030183	78	0.219
development of primary male sexual characteristics	GO:0046546	88	0.211
ventral spinal cord interneuron fate commitment	GO:0060579	14	0.209
immune effector process	GO:0002252	321	0.208
ear morphogenesis	GO:0042471	118	0.197	Mouse
transmembrane transport	GO:0055085	412	0.189
skeletal system morphogenesis	GO:0048705	203	0.187	Mouse
atrial cardiac muscle cell development	GO:0055014	2	0.182
stem cell differentiation	GO:0048863	268	0.182	Mouse
type b pancreatic cell differentiation	GO:0003309	13	0.176
ventral spinal cord interneuron differentiation	GO:0021514	16	0.174
regulation of cellular amine metabolic process	GO:0033238	20	0.174
positive regulation of glial cell differentiation	GO:0045687	21	0.174
male sex differentiation	GO:0046661	109	0.172
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	GO:0072039	4	0.170
cellular amino acid metabolic process	GO:0006520	103	0.165
t cell differentiation	GO:0030217	174	0.164
regulation of ion transmembrane transporter activity	GO:0032412	54	0.160
cardiac muscle tissue development	GO:0048738	130	0.155	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.152
spinal cord development	GO:0021510	81	0.152
muscle tissue development	GO:0060537	308	0.151	Mouse
endocrine pancreas development	GO:0031018	29	0.151	Mouse
cardiac muscle cell differentiation	GO:0055007	69	0.151
forebrain development	GO:0030900	302	0.147	Mouse
inorganic ion transmembrane transport	GO:0098660	234	0.145
heart morphogenesis	GO:0003007	178	0.145	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.143
epithelial cell development	GO:0002064	159	0.140	Mouse
cd4 positive alpha beta t cell activation	GO:0035710	45	0.140
neutral lipid metabolic process	GO:0006638	57	0.137
regulation of systemic arterial blood pressure mediated by a chemical signal	GO:0003044	33	0.136
positive regulation of cell development	GO:0010720	237	0.134	Mouse
lymphocyte differentiation	GO:0030098	242	0.134
striated muscle tissue development	GO:0014706	293	0.133	Mouse
embryonic skeletal system development	GO:0048706	120	0.130	Mouse
atrial cardiac muscle cell differentiation	GO:0055011	2	0.130
apoptotic process involved in morphogenesis	GO:0060561	25	0.129	Mouse
spleen development	GO:0048536	39	0.128
nephron development	GO:0072006	109	0.127	Mouse
amine metabolic process	GO:0009308	45	0.127
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.125	Mouse
positive regulation of oligodendrocyte differentiation	GO:0048714	9	0.124
regulation of cardioblast differentiation	GO:0051890	3	0.124
negative regulation of cell proliferation	GO:0008285	296	0.124
regulation of cardiac muscle cell proliferation	GO:0060043	23	0.123
regulation of gliogenesis	GO:0014013	50	0.122
male gonad development	GO:0008584	88	0.120
divalent metal ion transport	GO:0070838	172	0.120
ureteric bud morphogenesis	GO:0060675	62	0.119	Mouse
cell differentiation in spinal cord	GO:0021515	53	0.117
limb development	GO:0060173	166	0.115
camera type eye development	GO:0043010	266	0.115	Zebrafish Mouse
regulation of blood pressure	GO:0008217	93	0.114
wnt signaling pathway	GO:0016055	188	0.112
cellular lipid metabolic process	GO:0044255	323	0.112
cation transport	GO:0006812	399	0.112
bundle of his development	GO:0003166	4	0.112
inorganic cation transmembrane transport	GO:0098662	207	0.112
axon guidance	GO:0007411	141	0.111	Mouse
neuron migration	GO:0001764	122	0.110	Mouse
enteroendocrine cell differentiation	GO:0035883	16	0.109
cardiocyte differentiation	GO:0035051	87	0.108
oligodendrocyte development	GO:0014003	20	0.106
cardiac chamber morphogenesis	GO:0003206	93	0.106	Mouse
cerebral cortex neuron differentiation	GO:0021895	19	0.104
cardiac muscle cell proliferation	GO:0060038	31	0.104	Mouse
positive regulation of sodium ion transport	GO:0010765	13	0.104
epidermis development	GO:0008544	187	0.104
cellular ketone metabolic process	GO:0042180	84	0.103
regulation of glial cell differentiation	GO:0045685	41	0.102
regulation of system process	GO:0044057	200	0.102
regulation of stem cell differentiation	GO:2000736	50	0.102
renal system development	GO:0072001	225	0.100	Mouse
response to growth factor	GO:0070848	198	0.100
regulation of neuron differentiation	GO:0045664	281	0.100	Mouse
acylglycerol metabolic process	GO:0006639	55	0.098
cerebral cortex gabaergic interneuron differentiation	GO:0021892	9	0.098
regulation of cytokine production	GO:0001817	266	0.095
columnar cuboidal epithelial cell development	GO:0002066	29	0.095
gabaergic neuron differentiation	GO:0097154	11	0.094
ventricular cardiac muscle cell differentiation	GO:0055012	17	0.094
b cell activation involved in immune response	GO:0002312	50	0.093
heart trabecula morphogenesis	GO:0061384	26	0.093
cellular component assembly involved in morphogenesis	GO:0010927	139	0.091
response to lipopolysaccharide	GO:0032496	128	0.091
muscle cell development	GO:0055001	133	0.091
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.088	Mouse
pancreatic pp cell differentiation	GO:0003312	2	0.088
muscle contraction	GO:0006936	101	0.088
development of primary female sexual characteristics	GO:0046545	73	0.086	Mouse
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.086
lymph node development	GO:0048535	18	0.085
ureteric bud development	GO:0001657	94	0.085	Mouse
cardiac ventricle development	GO:0003231	83	0.084	Mouse
forebrain cell migration	GO:0021885	58	0.084	Mouse
regulation of muscle system process	GO:0090257	80	0.083
lung epithelial cell differentiation	GO:0060487	29	0.083	Mouse
muscle tissue morphogenesis	GO:0060415	53	0.083	Mouse
neuron fate specification	GO:0048665	30	0.083	Mouse
spinal cord dorsal ventral patterning	GO:0021513	23	0.082
respiratory tube development	GO:0030323	167	0.082	Mouse
central nervous system neuron differentiation	GO:0021953	162	0.082	Mouse
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.082
regulation of cardiac muscle tissue growth	GO:0055021	26	0.080
cartilage development	GO:0051216	140	0.080
ventricular cardiac muscle cell development	GO:0055015	11	0.080
respiratory system development	GO:0060541	190	0.079	Mouse
regulation of cardiac muscle tissue development	GO:0055024	31	0.079
pancreatic a cell fate commitment	GO:0003326	2	0.079
spinal cord patterning	GO:0021511	25	0.078
cardiac muscle contraction	GO:0060048	32	0.078
striated muscle cell development	GO:0055002	125	0.078
muscle cell differentiation	GO:0042692	261	0.078
cd4 positive alpha beta t cell differentiation	GO:0043367	41	0.077
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.077
mesenchyme development	GO:0060485	152	0.077	Mouse
positive regulation of transcription via serum response element binding	GO:0010735	1	0.076
forebrain neuron fate commitment	GO:0021877	13	0.076
paramesonephric duct development	GO:0061205	3	0.076
glandular epithelial cell differentiation	GO:0002067	38	0.076	Mouse
regulation of systemic arterial blood pressure	GO:0003073	61	0.076
homeostasis of number of cells	GO:0048872	210	0.076
sensory organ morphogenesis	GO:0090596	242	0.075	Zebrafish Mouse
spinal cord motor neuron differentiation	GO:0021522	35	0.075
positive regulation of ion transmembrane transporter activity	GO:0032414	15	0.075
lung cell differentiation	GO:0060479	30	0.075	Mouse
negative regulation of stem cell differentiation	GO:2000737	14	0.074
neural nucleus development	GO:0048857	22	0.074
nephron epithelium development	GO:0072009	92	0.074	Mouse
positive regulation of calcium ion transmembrane transporter activity	GO:1901021	8	0.074
cell type specific apoptotic process	GO:0097285	268	0.073
myeloid cell differentiation	GO:0030099	233	0.073
regulation of organ growth	GO:0046620	61	0.073	Mouse
negative regulation of stem cell maintenance	GO:1902455	4	0.073
sodium ion transport	GO:0006814	73	0.073
positive regulation of protein modification process	GO:0031401	299	0.072
striated muscle contraction	GO:0006941	45	0.072
lung epithelium development	GO:0060428	37	0.072	Mouse
neuron fate determination	GO:0048664	9	0.072	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.072
left right pattern formation	GO:0060972	23	0.072
positive regulation of transcription initiation from rna polymerase ii promoter	GO:0060261	5	0.071
digestive system development	GO:0055123	200	0.070	Human Mouse
cellular response to growth factor stimulus	GO:0071363	197	0.070
regulation of thyroid hormone generation	GO:2000609	4	0.070
axonogenesis	GO:0007409	274	0.070	Mouse
his purkinje system development	GO:0003164	4	0.070
organ growth	GO:0035265	117	0.070	Mouse
developmental induction	GO:0031128	34	0.070
trabecula formation	GO:0060343	24	0.070
myeloid leukocyte differentiation	GO:0002573	119	0.069
positive regulation of protein complex assembly	GO:0031334	45	0.069
skeletal system development	GO:0001501	356	0.069	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.069	Mouse
chondrocyte differentiation	GO:0002062	72	0.069
chromatin organization	GO:0006325	206	0.069	Mouse
locomotory behavior	GO:0007626	195	0.069	Mouse
epithelial cell proliferation	GO:0050673	174	0.068	Mouse
regulation of ion transmembrane transport	GO:0034765	119	0.068
ear development	GO:0043583	200	0.068	Mouse
lung development	GO:0030324	164	0.068	Mouse
spinal cord oligodendrocyte cell fate specification	GO:0021530	3	0.068
anion transport	GO:0006820	177	0.067
ventricular cardiac myofibril assembly	GO:0055005	3	0.067
positive regulation of neuron differentiation	GO:0045666	141	0.066	Mouse
negative regulation of wnt signaling pathway	GO:0030178	73	0.065
nephric duct formation	GO:0072179	4	0.065
skeletal muscle cell differentiation	GO:0035914	66	0.065
his purkinje system cell differentiation	GO:0060932	2	0.065
branching morphogenesis of an epithelial tube	GO:0048754	159	0.065	Mouse
mesenchymal cell differentiation	GO:0048762	107	0.064	Mouse
regulation of muscle tissue development	GO:1901861	97	0.064
pancreas development	GO:0031016	57	0.064	Mouse
cardiac muscle cell development	GO:0055013	39	0.064
regulation of protein complex assembly	GO:0043254	83	0.063
negative regulation of cellular protein metabolic process	GO:0032269	247	0.063
regulation of fat cell differentiation	GO:0045598	81	0.063
leukocyte homeostasis	GO:0001776	79	0.063
divalent inorganic cation transport	GO:0072511	178	0.063
alpha beta t cell activation	GO:0046631	91	0.063
endoderm development	GO:0007492	45	0.062
negative regulation of cell development	GO:0010721	169	0.062	Mouse
forebrain generation of neurons	GO:0021872	63	0.062	Mouse
odontogenesis	GO:0042476	78	0.062
telencephalon development	GO:0021537	186	0.062	Mouse
histone methylation	GO:0016571	71	0.061
lung morphogenesis	GO:0060425	50	0.061	Mouse
positive regulation of gliogenesis	GO:0014015	27	0.061
circulatory system process	GO:0003013	197	0.060	Mouse
cell fate commitment involved in pattern specification	GO:0060581	14	0.060
paraxial mesodermal cell fate commitment	GO:0048343	2	0.059	Mouse
hippocampus development	GO:0021766	52	0.059
regulation of ion transport	GO:0043269	215	0.059
positive regulation of cellular component biogenesis	GO:0044089	94	0.059
cardiac cell development	GO:0055006	41	0.058
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	GO:0072040	4	0.058
peptidyl tyrosine phosphorylation	GO:0018108	143	0.058
macromolecule methylation	GO:0043414	120	0.058
cell differentiation involved in kidney development	GO:0061005	33	0.058	Mouse
peptidyl amino acid modification	GO:0018193	336	0.058
endocrine process	GO:0050886	39	0.057
negative regulation of cellular component organization	GO:0051129	194	0.057
blood circulation	GO:0008015	195	0.057	Mouse
cell fate determination involved in pattern specification	GO:0060582	1	0.057
positive regulation of metanephric glomerulus development	GO:0072300	4	0.057
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.056	Mouse
mature b cell differentiation involved in immune response	GO:0002313	9	0.056
cardiac ventricle morphogenesis	GO:0003208	50	0.056	Mouse
nephron tubule morphogenesis	GO:0072078	68	0.056	Mouse
kidney rudiment formation	GO:0072003	3	0.055
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.055
macrophage differentiation	GO:0030225	20	0.055
positive regulation of cellular amine metabolic process	GO:0033240	5	0.055
negative regulation of mesenchymal cell apoptotic process involved in metanephros development	GO:1900212	4	0.054
epithelial tube morphogenesis	GO:0060562	303	0.054	Mouse
fat cell differentiation	GO:0045444	160	0.054
regionalization	GO:0003002	337	0.054	Mouse
leukocyte differentiation	GO:0002521	342	0.054
metanephric dct cell differentiation	GO:0072240	3	0.053
spinal cord oligodendrocyte cell differentiation	GO:0021529	3	0.053
mesenchymal cell apoptotic process involved in nephron morphogenesis	GO:1901145	4	0.053
regulation of calcium ion transmembrane transport	GO:1903169	20	0.053
odontogenesis of dentin containing tooth	GO:0042475	66	0.052
endocrine system development	GO:0035270	98	0.052
cytokine production	GO:0001816	319	0.052
oligodendrocyte differentiation	GO:0048709	53	0.052
regulation of epithelial cell proliferation	GO:0050678	141	0.052	Mouse
positive regulation of voltage gated calcium channel activity	GO:1901387	2	0.051
positive regulation of cell cycle	GO:0045787	92	0.051	Mouse
paraxial mesodermal cell differentiation	GO:0048342	2	0.051	Mouse
phospholipid metabolic process	GO:0006644	87	0.051
glandular epithelial cell development	GO:0002068	15	0.051
chemotaxis	GO:0006935	247	0.051	Mouse
lymphocyte activation involved in immune response	GO:0002285	93	0.050
glomerulus development	GO:0032835	40	0.050	Mouse
dna templated transcription initiation	GO:0006352	13	0.050
type b pancreatic cell development	GO:0003323	10	0.050
striated muscle cell proliferation	GO:0014855	39	0.050	Mouse
cellular macromolecule catabolic process	GO:0044265	206	0.049
stem cell maintenance	GO:0019827	130	0.049
cellular modified amino acid metabolic process	GO:0006575	63	0.049
regulation of oligodendrocyte differentiation	GO:0048713	23	0.049
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.049
monocarboxylic acid metabolic process	GO:0032787	191	0.049
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.049	Mouse
regulation of cell motility	GO:2000145	236	0.048	Mouse
cellular amine metabolic process	GO:0044106	44	0.048
myoblast differentiation involved in skeletal muscle regeneration	GO:0014835	3	0.048
trabecula morphogenesis	GO:0061383	40	0.048
hypophysis morphogenesis	GO:0048850	3	0.048
gliogenesis	GO:0042063	141	0.048
negative regulation of nervous system development	GO:0051961	156	0.048	Mouse
metanephros development	GO:0001656	79	0.047	Mouse
glial cell differentiation	GO:0010001	131	0.047
regulation of defense response	GO:0031347	233	0.047
actin cytoskeleton organization	GO:0030036	220	0.047
negative regulation of protein metabolic process	GO:0051248	282	0.046
alpha beta t cell differentiation	GO:0046632	69	0.046
regulation of metal ion transport	GO:0010959	106	0.046
glial cell development	GO:0021782	54	0.046
negative regulation of molecular function	GO:0044092	258	0.046	Mouse
ventricular trabecula myocardium morphogenesis	GO:0003222	11	0.046
forebrain neuron differentiation	GO:0021879	52	0.046	Mouse
glial cell fate specification	GO:0021780	5	0.045
regulation of heart growth	GO:0060420	31	0.045
regulation of cytokine secretion	GO:0050707	61	0.045
regulation of cation channel activity	GO:2001257	22	0.045
negative regulation of cellular response to growth factor stimulus	GO:0090288	46	0.044
negative regulation of prostatic bud formation	GO:0060686	4	0.044
retina development in camera type eye	GO:0060041	119	0.043
cell cell signaling involved in cell fate commitment	GO:0045168	35	0.043
heart growth	GO:0060419	45	0.043	Mouse
modification dependent macromolecule catabolic process	GO:0043632	133	0.043
canonical wnt signaling pathway	GO:0060070	130	0.043
forebrain regionalization	GO:0021871	25	0.043
methylation	GO:0032259	134	0.043
pancreatic a cell differentiation	GO:0003310	7	0.042
somatotropin secreting cell differentiation	GO:0060126	4	0.042
heart process	GO:0003015	94	0.042
embryonic heart tube morphogenesis	GO:0003143	51	0.042
ventral spinal cord development	GO:0021517	48	0.042
regulation of canonical wnt signaling pathway	GO:0060828	82	0.042
determination of left right symmetry	GO:0007368	80	0.042
epithelial tube formation	GO:0072175	130	0.042
digestive tract development	GO:0048565	190	0.041	Human Mouse
renal tubule development	GO:0061326	87	0.041	Mouse
regulation of circadian rhythm	GO:0042752	58	0.041
regulation of blood volume by renin angiotensin	GO:0002016	7	0.041
regulation of mesenchymal cell apoptotic process involved in metanephros development	GO:1900211	4	0.041
intestinal epithelial cell differentiation	GO:0060575	14	0.041
biological phase	GO:0044848	20	0.040
skeletal muscle organ development	GO:0060538	163	0.040
appendage development	GO:0048736	166	0.040
epithelial cell differentiation involved in kidney development	GO:0035850	23	0.040	Mouse
calcium ion transport	GO:0006816	159	0.040
segmentation	GO:0035282	93	0.040	Mouse
regulation of systemic arterial blood pressure by hormone	GO:0001990	25	0.039
somatic stem cell maintenance	GO:0035019	47	0.039
sclerotome development	GO:0061056	4	0.039
negative regulation of neuron differentiation	GO:0045665	101	0.039	Mouse
limb morphogenesis	GO:0035108	149	0.039
placenta development	GO:0001890	140	0.039	Mouse
synaptic transmission	GO:0007268	329	0.039
modification dependent protein catabolic process	GO:0019941	133	0.039
pancreatic pp cell fate commitment	GO:0003329	2	0.039
regulation of chromosome organization	GO:0033044	83	0.038
regulation of systemic arterial blood pressure by renin angiotensin	GO:0003081	20	0.038
negative regulation of cell migration	GO:0030336	59	0.038
histone lysine methylation	GO:0034968	50	0.037
positive regulation of stem cell differentiation	GO:2000738	23	0.037
regulation of cartilage development	GO:0061035	44	0.037
neural tube development	GO:0021915	160	0.037	Mouse
heart contraction	GO:0060047	93	0.036
transcription initiation from rna polymerase ii promoter	GO:0006367	8	0.036
negative regulation of protein modification process	GO:0031400	163	0.036
metanephric s shaped body morphogenesis	GO:0072284	2	0.036
sulfur compound metabolic process	GO:0006790	100	0.035
regulation of wnt signaling pathway	GO:0030111	123	0.035
regulation of anatomical structure size	GO:0090066	178	0.035	Mouse
regulation of asymmetric cell division	GO:0009786	4	0.035
regulation of chondrocyte differentiation	GO:0032330	33	0.035
regulation of secretion by cell	GO:1903530	249	0.035	Mouse
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.035
ventricular cardiac muscle tissue development	GO:0003229	38	0.035	Mouse
connective tissue development	GO:0061448	179	0.035	Mouse
regulation of muscle cell apoptotic process	GO:0010660	17	0.035
female sex differentiation	GO:0046660	84	0.035	Mouse
ubiquitin dependent protein catabolic process	GO:0006511	129	0.035
organelle assembly	GO:0070925	177	0.034
morphogenesis of a branching structure	GO:0001763	203	0.034	Mouse
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.034
limbic system development	GO:0021761	72	0.034
epithelial to mesenchymal transition	GO:0001837	47	0.034
pituitary gland development	GO:0021983	38	0.034
embryonic skeletal system morphogenesis	GO:0048704	91	0.034	Mouse
smoothened signaling pathway	GO:0007224	105	0.034	Mouse
regulation of calcium ion transport	GO:0051924	69	0.034
digestive tract morphogenesis	GO:0048546	147	0.033	Mouse
negative regulation of cell morphogenesis involved in differentiation	GO:0010771	48	0.033
muscle cell apoptotic process	GO:0010657	18	0.033
tube closure	GO:0060606	91	0.033
regulation of osteoblast differentiation	GO:0045667	67	0.033
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.032
metanephric loop of henle development	GO:0072236	4	0.032
hematopoietic progenitor cell differentiation	GO:0002244	143	0.032
positive regulation of dna templated transcription initiation	GO:2000144	5	0.032
bone morphogenesis	GO:0060349	78	0.032
bmp signaling pathway	GO:0030509	93	0.032	Mouse
astrocyte differentiation	GO:0048708	43	0.032
negative regulation of intracellular signal transduction	GO:1902532	167	0.032
negative regulation of cellular amine metabolic process	GO:0033239	1	0.032
regulation of dna templated transcription initiation	GO:2000142	7	0.032
determination of heart left right asymmetry	GO:0061371	48	0.031
neuronal action potential	GO:0019228	54	0.031
kidney morphogenesis	GO:0060993	83	0.031	Mouse
regulation of apoptotic signaling pathway	GO:2001233	197	0.031
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.031
lateral inhibition	GO:0046331	1	0.031
oxidation reduction process	GO:0055114	342	0.031
dna metabolic process	GO:0006259	303	0.031
cardiac pacemaker cell fate commitment	GO:0060927	1	0.031
leukocyte migration	GO:0050900	124	0.031
plasma cell differentiation	GO:0002317	3	0.031
skin development	GO:0043588	220	0.031
regulation of neurotransmitter levels	GO:0001505	87	0.031
nephron epithelium morphogenesis	GO:0072088	68	0.030	Mouse
globus pallidus development	GO:0021759	2	0.030
multicellular organismal signaling	GO:0035637	91	0.030
mesonephros development	GO:0001823	97	0.030	Mouse
cellular protein catabolic process	GO:0044257	155	0.030
leydig cell differentiation	GO:0033327	10	0.030
response to transforming growth factor beta	GO:0071559	88	0.030
t cell activation	GO:0042110	289	0.030
macromolecule catabolic process	GO:0009057	281	0.030
regulation of organ morphogenesis	GO:2000027	144	0.030	Mouse
dct cell differentiation	GO:0072069	3	0.030
pharynx development	GO:0060465	1	0.030	Human
heterocycle catabolic process	GO:0046700	280	0.029
cardiac myofibril assembly	GO:0055003	12	0.029
regulation of carbohydrate biosynthetic process	GO:0043255	40	0.029
response to inorganic substance	GO:0010035	96	0.029
regulation of muscle contraction	GO:0006937	49	0.029
regulation of kinase activity	GO:0043549	249	0.029	Mouse
diencephalon development	GO:0021536	63	0.029
thyroid hormone metabolic process	GO:0042403	16	0.029
small molecule biosynthetic process	GO:0044283	132	0.029
intestinal epithelial cell development	GO:0060576	12	0.029
pharyngeal system development	GO:0060037	17	0.029
carbohydrate metabolic process	GO:0005975	230	0.029	Mouse
axon ensheathment	GO:0008366	76	0.029
neuron projection guidance	GO:0097485	141	0.028	Mouse
sarcomere organization	GO:0045214	24	0.028
forebrain morphogenesis	GO:0048853	17	0.028
protein catabolic process	GO:0030163	221	0.028
response to osmotic stress	GO:0006970	21	0.028
polarity specification of proximal distal axis	GO:0010085	2	0.028
kidney epithelium development	GO:0072073	121	0.028	Mouse
embryonic heart tube left right pattern formation	GO:0060971	5	0.028
regulation of neural precursor cell proliferation	GO:2000177	70	0.028	Mouse
regulation of interleukin 8 production	GO:0032677	3	0.028
positive regulation of heart contraction	GO:0045823	14	0.028
gonad development	GO:0008406	141	0.028	Mouse
regulation of cardiac muscle cell apoptotic process	GO:0010665	9	0.027
cell differentiation in hindbrain	GO:0021533	24	0.027	Mouse
atrioventricular node development	GO:0003162	3	0.027
type ii pneumocyte differentiation	GO:0060510	7	0.027
atrioventricular node cell development	GO:0060928	2	0.027
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.027	Mouse
embryonic digit morphogenesis	GO:0042733	56	0.027
mesonephric epithelium development	GO:0072163	94	0.027	Mouse
cardiac muscle tissue growth	GO:0055017	37	0.027	Mouse
hormone metabolic process	GO:0042445	86	0.027
covalent chromatin modification	GO:0016569	163	0.027
hypothalamus development	GO:0021854	16	0.027
regulation of organ formation	GO:0003156	34	0.026
atrioventricular node cell differentiation	GO:0060922	2	0.026
mature b cell differentiation	GO:0002335	13	0.026
protein methylation	GO:0006479	81	0.026
actomyosin structure organization	GO:0031032	56	0.026
erythrocyte differentiation	GO:0030218	88	0.026
positive regulation of transmembrane transport	GO:0034764	29	0.026
response to organonitrogen compound	GO:0010243	246	0.026
embryonic epithelial tube formation	GO:0001838	130	0.026
small gtpase mediated signal transduction	GO:0007264	97	0.026
interferon gamma production	GO:0032609	67	0.026
negative regulation of mesenchymal cell proliferation	GO:0072201	3	0.026
histone modification	GO:0016570	159	0.026
cell fate specification	GO:0001708	72	0.026	Mouse
regulation of kidney size	GO:0035564	3	0.026
striated muscle cell apoptotic process	GO:0010658	12	0.025
olfactory bulb development	GO:0021772	30	0.025
metanephric nephron development	GO:0072210	34	0.025	Mouse
regulation of inflammatory response	GO:0050727	147	0.025
nephron tubule development	GO:0072080	84	0.025	Mouse
cardiac muscle cell fate commitment	GO:0060923	6	0.025
regulation of calcium ion transmembrane transporter activity	GO:1901019	20	0.025
positive regulation of hormone metabolic process	GO:0032352	3	0.025
regulation of leukocyte differentiation	GO:1902105	159	0.025
positive regulation of ion transmembrane transport	GO:0034767	24	0.025
oligodendrocyte cell fate commitment	GO:0021779	5	0.025
regulation of cardiac muscle contraction	GO:0055117	21	0.025
mesonephric tubule morphogenesis	GO:0072171	63	0.025	Mouse
regulation of transporter activity	GO:0032409	57	0.025
regulation of stem cell maintenance	GO:2000036	17	0.025
gastrulation	GO:0007369	116	0.025	Mouse
pericardium development	GO:0060039	16	0.024
positive regulation of stem cell proliferation	GO:2000648	59	0.024	Mouse
glycoprotein metabolic process	GO:0009100	116	0.024
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.024
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.024
negative regulation of cell motility	GO:2000146	61	0.024
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	26	0.024
regulation of membrane potential	GO:0042391	192	0.024
asymmetric stem cell division	GO:0098722	3	0.024
regulation of blood circulation	GO:1903522	93	0.024
regulation of interferon gamma production	GO:0032649	57	0.023
spermatogenesis	GO:0007283	284	0.023	Mouse
regulation of kidney development	GO:0090183	40	0.023	Mouse
regulation of secretion	GO:0051046	274	0.023	Mouse
regulation of bmp signaling pathway	GO:0030510	60	0.023	Mouse
carbohydrate derivative biosynthetic process	GO:1901137	183	0.023
venous blood vessel development	GO:0060841	13	0.023
tongue development	GO:0043586	18	0.023
positive regulation of cardioblast differentiation	GO:0051891	3	0.023
negative regulation of neuron death	GO:1901215	98	0.023
molting cycle	GO:0042303	90	0.023
regulation of feeding behavior	GO:0060259	3	0.023
interleukin 8 production	GO:0032637	4	0.023
regulation of striated muscle cell apoptotic process	GO:0010662	11	0.023
negative regulation of metanephros development	GO:0072217	6	0.023
ensheathment of neurons	GO:0007272	76	0.023
glucose homeostasis	GO:0042593	128	0.022	Mouse
activation of immune response	GO:0002253	138	0.022
primary neural tube formation	GO:0014020	95	0.022
regulation of histone methylation	GO:0031060	30	0.022
metencephalon development	GO:0022037	89	0.022
chromatin modification	GO:0016568	187	0.022	Mouse

Foxe1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability	Func Analog Org
nervous system disease	DOID:863	0.036
disease of anatomical entity	DOID:7	0.036	Human
sensory system disease	DOID:0050155	0.028

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