IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Gins2

GINS complex subunit 2 (Psf2 homolog)

(Aliases: AI323585,2210013I18Rik,4833427B12Rik,Pfs2)

Ensembl: ENSMUSG00000031821
Entrez: 272551
UniProtKB: Q9D600

Process Predictions
Disease Predictions

Gins2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
dna metabolic process	GO:0006259	303	0.107
cellular response to dna damage stimulus	GO:0006974	207	0.080
dna repair	GO:0006281	107	0.056
cellular amino acid metabolic process	GO:0006520	103	0.055
positive regulation of programmed cell death	GO:0043068	218	0.046
organelle fission	GO:0048285	170	0.041
dna recombination	GO:0006310	92	0.037
regulation of cellular ketone metabolic process	GO:0010565	66	0.036
nuclear division	GO:0000280	158	0.035
positive regulation of cell death	GO:0010942	224	0.033
chromatin modification	GO:0016568	187	0.031
chromatin organization	GO:0006325	206	0.030
regulation of cell cycle	GO:0051726	281	0.030
chromosome segregation	GO:0007059	48	0.028
macromolecule catabolic process	GO:0009057	281	0.028
nucleobase containing small molecule metabolic process	GO:0055086	352	0.028
cellular amine metabolic process	GO:0044106	44	0.028
covalent chromatin modification	GO:0016569	163	0.027
meiotic nuclear division	GO:0007126	115	0.026
double strand break repair	GO:0006302	48	0.026
negative regulation of protein processing	GO:0010955	79	0.024
oxidation reduction process	GO:0055114	342	0.024
nucleoside phosphate metabolic process	GO:0006753	338	0.024
circulatory system process	GO:0003013	197	0.024
asymmetric stem cell division	GO:0098722	3	0.024
positive regulation of apoptotic process	GO:0043065	217	0.022
nucleotide metabolic process	GO:0009117	332	0.022
male gamete generation	GO:0048232	285	0.022
cell type specific apoptotic process	GO:0097285	268	0.022
apoptotic signaling pathway	GO:0097190	306	0.021
cellular homeostasis	GO:0019725	240	0.021
intrinsic apoptotic signaling pathway	GO:0097193	132	0.021
negative regulation of cell proliferation	GO:0008285	296	0.021
nucleotide biosynthetic process	GO:0009165	78	0.021
blood circulation	GO:0008015	195	0.020
purine ribonucleoside metabolic process	GO:0046128	241	0.020
negative regulation of phosphorylation	GO:0042326	166	0.020
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.020
response to radiation	GO:0009314	165	0.020
embryonic epithelial tube formation	GO:0001838	130	0.019
cellular ketone metabolic process	GO:0042180	84	0.019
striated muscle tissue development	GO:0014706	293	0.019
protein processing	GO:0016485	163	0.019
regulation of cellular amino acid metabolic process	GO:0006521	5	0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.018
cell adhesion	GO:0007155	329	0.018
ribose phosphate metabolic process	GO:0019693	291	0.018
carbohydrate homeostasis	GO:0033500	128	0.017
protein maturation	GO:0051604	176	0.017
cellular lipid metabolic process	GO:0044255	323	0.017
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.017
cellular response to growth factor stimulus	GO:0071363	197	0.016
negative regulation of protein metabolic process	GO:0051248	282	0.016
tube formation	GO:0035148	140	0.016
metaphase anaphase transition of mitotic cell cycle	GO:0007091	9	0.016
cellular protein catabolic process	GO:0044257	155	0.016
ribonucleoside metabolic process	GO:0009119	245	0.016
negative regulation of cellular protein metabolic process	GO:0032269	247	0.016
b cell activation	GO:0042113	161	0.016
neural tube development	GO:0021915	160	0.016
amine metabolic process	GO:0009308	45	0.016
epithelial tube morphogenesis	GO:0060562	303	0.016
purine ribonucleotide metabolic process	GO:0009150	290	0.016
peptidyl amino acid modification	GO:0018193	336	0.015
germ cell development	GO:0007281	185	0.015
purine nucleotide metabolic process	GO:0006163	302	0.015
regulation of cellular amine metabolic process	GO:0033238	20	0.015
leukocyte mediated immunity	GO:0002443	174	0.015
regulation of response to wounding	GO:1903034	189	0.015
regulation of cellular response to stress	GO:0080135	159	0.015
somatic recombination of immunoglobulin gene segments	GO:0016447	42	0.015
transmembrane transport	GO:0055085	412	0.015
cell division	GO:0051301	120	0.015
organelle localization	GO:0051640	179	0.015
sister chromatid segregation	GO:0000819	20	0.015
morphogenesis of embryonic epithelium	GO:0016331	159	0.014
heterocycle catabolic process	GO:0046700	280	0.014
ion transmembrane transport	GO:0034220	361	0.014
intracellular mrna localization	GO:0008298	4	0.014
purine containing compound metabolic process	GO:0072521	311	0.014
epithelial tube formation	GO:0072175	130	0.014
response to organonitrogen compound	GO:0010243	246	0.014
muscle tissue development	GO:0060537	308	0.014
ribonucleotide metabolic process	GO:0009259	291	0.014
positive regulation of cellular amine metabolic process	GO:0033240	5	0.014
peptidyl tyrosine phosphorylation	GO:0018108	143	0.013
blood vessel morphogenesis	GO:0048514	285	0.013
lymphocyte mediated immunity	GO:0002449	139	0.013
regulation of hydrolase activity	GO:0051336	246	0.013
monocarboxylic acid metabolic process	GO:0032787	191	0.013
gland development	GO:0048732	330	0.013
spermatogenesis	GO:0007283	284	0.013
alpha amino acid metabolic process	GO:1901605	59	0.013
carbohydrate derivative biosynthetic process	GO:1901137	183	0.013
immunoglobulin mediated immune response	GO:0016064	69	0.013
response to growth factor	GO:0070848	198	0.013
cation transport	GO:0006812	399	0.013
nucleoside catabolic process	GO:0009164	206	0.013
regionalization	GO:0003002	337	0.013
negative regulation of protein modification process	GO:0031400	163	0.012
neuron death	GO:0070997	154	0.012
glucose homeostasis	GO:0042593	128	0.012
histone modification	GO:0016570	159	0.012
nucleoside triphosphate metabolic process	GO:0009141	230	0.012
rhythmic process	GO:0048511	174	0.012
mapk cascade	GO:0000165	281	0.012
nucleotide catabolic process	GO:0009166	217	0.012
regulation of cell cycle phase transition	GO:1901987	77	0.012
fertilization	GO:0009566	127	0.012
organonitrogen compound biosynthetic process	GO:1901566	192	0.012
tube closure	GO:0060606	91	0.011
peptidyl tyrosine modification	GO:0018212	145	0.011
positive regulation of cell development	GO:0010720	237	0.011
adaptive immune response	GO:0002250	155	0.011
lateral inhibition	GO:0046331	1	0.011
membrane organization	GO:0061024	245	0.011
response to inorganic substance	GO:0010035	96	0.011
regulation of neuron apoptotic process	GO:0043523	122	0.011
cell fate commitment	GO:0045165	210	0.011
regulation of homeostatic process	GO:0032844	182	0.011
regulation of transferase activity	GO:0051338	263	0.011
response to ionizing radiation	GO:0010212	42	0.011
developmental maturation	GO:0021700	193	0.010
reactive oxygen species metabolic process	GO:0072593	84	0.010
negative regulation of phosphorus metabolic process	GO:0010563	184	0.010
cellular nitrogen compound catabolic process	GO:0044270	280	0.010
hematopoietic progenitor cell differentiation	GO:0002244	143	0.010
positive regulation of cell cycle	GO:0045787	92	0.010
regulation of mapk cascade	GO:0043408	248	0.010
regulation of proteolysis	GO:0030162	164	0.010
inflammatory response	GO:0006954	244	0.010
purine ribonucleoside catabolic process	GO:0046130	205	0.010
immune effector process	GO:0002252	321	0.010
anatomical structure homeostasis	GO:0060249	145	0.010
negative regulation of cell development	GO:0010721	169	0.010
production of molecular mediator of immune response	GO:0002440	103	0.010
regulation of neuron differentiation	GO:0045664	281	0.010
microtubule based process	GO:0007017	236	0.010
cytoplasmic transport	GO:0016482	234	0.010
cellular macromolecule catabolic process	GO:0044265	206	0.010
aromatic compound catabolic process	GO:0019439	286	0.010
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.010

Gins2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.105
cancer	DOID:162	0.050
disease of metabolism	DOID:0014667	0.030
inherited metabolic disorder	DOID:655	0.027
organ system cancer	DOID:0050686	0.025
thoracic cancer	DOID:5093	0.016
carbohydrate metabolic disorder	DOID:2978	0.015
breast cancer	DOID:1612	0.014

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