| dna metabolic process | GO:0006259 | 303 | 0.468 | |
| microtubule based process | GO:0007017 | 236 | 0.225 | |
| chromatin organization | GO:0006325 | 206 | 0.201 | Human |
| dna repair | GO:0006281 | 107 | 0.181 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.138 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.125 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.103 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.096 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.093 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.091 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.084 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.084 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.080 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.079 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.077 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.069 | |
| organelle assembly | GO:0070925 | 177 | 0.067 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.067 | |
| rna catabolic process | GO:0006401 | 29 | 0.067 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.065 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.063 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.062 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 15 | 0.062 | |
| protein localization to organelle | GO:0033365 | 185 | 0.062 | Human |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.061 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.059 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.059 | |
| gene silencing | GO:0016458 | 38 | 0.057 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.055 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.054 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.051 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.051 | |
| histone methylation | GO:0016571 | 71 | 0.050 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.049 | |
| base excision repair | GO:0006284 | 9 | 0.049 | |
| cilium morphogenesis | GO:0060271 | 102 | 0.049 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.049 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.048 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.046 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.046 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.046 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.045 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.045 | |
| protein alkylation | GO:0008213 | 81 | 0.043 | |
| methylation | GO:0032259 | 134 | 0.042 | |
| protein methylation | GO:0006479 | 81 | 0.042 | |
| endocytosis | GO:0006897 | 168 | 0.042 | |
| chromatin modification | GO:0016568 | 187 | 0.040 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.040 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.039 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.039 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.037 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.037 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.036 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.036 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.035 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.035 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.034 | |
| regulation of protein localization | GO:0032880 | 231 | 0.034 | |
| protein dna complex subunit organization | GO:0071824 | 28 | 0.034 | |
| organelle localization | GO:0051640 | 179 | 0.033 | |
| dna dependent dna replication maintenance of fidelity | GO:0045005 | 3 | 0.033 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.033 | |
| regulation of ubiquitin protein ligase activity involved in mitotic cell cycle | GO:0051439 | 1 | 0.033 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.033 | |
| positive regulation of cell cycle phase transition | GO:1901989 | 17 | 0.032 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.032 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.032 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.032 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.032 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.031 | |
| regulation of histone modification | GO:0031056 | 56 | 0.031 | |
| recombinational repair | GO:0000725 | 21 | 0.031 | |
| negative regulation of nlrp3 inflammasome complex assembly | GO:1900226 | 2 | 0.031 | |
| regulation of actin nucleation | GO:0051125 | 4 | 0.031 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.031 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.031 | |
| regulation of histone h3 k4 methylation | GO:0051569 | 12 | 0.031 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.030 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.030 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.029 | |
| regulation of histone methylation | GO:0031060 | 30 | 0.029 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.029 | |
| positive regulation of chromosome organization | GO:2001252 | 33 | 0.029 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.028 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.028 | |
| regulation of protein transport | GO:0051223 | 163 | 0.028 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.028 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.027 | |
| histone modification | GO:0016570 | 159 | 0.027 | |
| germ cell development | GO:0007281 | 185 | 0.027 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.027 | |
| camera type eye development | GO:0043010 | 266 | 0.027 | |
| positive regulation of histone modification | GO:0031058 | 28 | 0.026 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.025 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.025 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.025 | |
| histone lysine methylation | GO:0034968 | 50 | 0.025 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.025 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.024 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.024 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.024 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.024 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.024 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.024 | |
| macromolecule methylation | GO:0043414 | 120 | 0.024 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.023 | |
| immune effector process | GO:0002252 | 321 | 0.023 | |
| organelle fission | GO:0048285 | 170 | 0.023 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.023 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.023 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.023 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.023 | |
| nuclear division | GO:0000280 | 158 | 0.022 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.022 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.022 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.022 | |
| operant conditioning | GO:0035106 | 2 | 0.022 | |
| innate immune response | GO:0045087 | 157 | 0.022 | |
| protein polymerization | GO:0051258 | 57 | 0.022 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.022 | |
| rna interference | GO:0016246 | 2 | 0.021 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.021 | |
| regulation of chromatin organization | GO:1902275 | 57 | 0.021 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.021 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.021 | |
| intracellular protein transport | GO:0006886 | 204 | 0.021 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.021 | |
| amine metabolic process | GO:0009308 | 45 | 0.021 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.021 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.020 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.020 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.020 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.020 | |
| viral gene expression | GO:0019080 | 3 | 0.020 | |
| histone h3 k4 methylation | GO:0051568 | 23 | 0.020 | |
| dna replication | GO:0006260 | 52 | 0.019 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.019 | |
| skeletal system development | GO:0001501 | 356 | 0.019 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.019 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.019 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.019 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.019 | |
| meiosis i | GO:0007127 | 60 | 0.019 | |
| organism emergence from protective structure | GO:0071684 | 4 | 0.019 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.018 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.018 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.018 | |
| cell division | GO:0051301 | 120 | 0.018 | |
| mitotic cell cycle checkpoint | GO:0007093 | 31 | 0.018 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.018 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.018 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.018 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.018 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.017 | |
| hatching | GO:0035188 | 4 | 0.017 | |
| metencephalon development | GO:0022037 | 89 | 0.017 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.017 | |
| chromosome segregation | GO:0007059 | 48 | 0.017 | |
| gtp catabolic process | GO:0006184 | 143 | 0.017 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.017 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.017 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.017 | |
| viral transcription | GO:0019083 | 3 | 0.017 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.017 | |
| nucleobase biosynthetic process | GO:0046112 | 3 | 0.017 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 49 | 0.016 | |
| positive regulation of histone methylation | GO:0031062 | 16 | 0.016 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.016 | |
| single organism nuclear import | GO:1902593 | 95 | 0.016 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.016 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.016 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.016 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.016 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.016 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.016 | |
| nuclear transport | GO:0051169 | 139 | 0.016 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.016 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.016 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.015 | |
| protein ubiquitination | GO:0016567 | 171 | 0.015 | |
| regulation of adaptive immune response | GO:0002819 | 90 | 0.015 | |
| dna geometric change | GO:0032392 | 7 | 0.015 | |
| negative regulation of histone h3 k9 methylation | GO:0051573 | 4 | 0.015 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.015 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.015 | |
| calcium ion transport | GO:0006816 | 159 | 0.015 | |
| regulation of g1 s transition of mitotic cell cycle | GO:2000045 | 35 | 0.015 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.015 | |
| metaphase plate congression | GO:0051310 | 2 | 0.015 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.015 | |
| positive regulation of chromosome segregation | GO:0051984 | 4 | 0.015 | |
| skin development | GO:0043588 | 220 | 0.015 | |
| cellular response to organic cyclic compound | GO:0071407 | 87 | 0.015 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.015 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.015 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.015 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.015 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.015 | |
| dna recombination | GO:0006310 | 92 | 0.015 | |
| protein processing | GO:0016485 | 163 | 0.014 | |
| atp catabolic process | GO:0006200 | 55 | 0.014 | |
| rna dependent dna replication | GO:0006278 | 3 | 0.014 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.014 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.014 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.014 | |
| gene silencing by rna | GO:0031047 | 19 | 0.014 | |
| regulation of cell activation | GO:0050865 | 289 | 0.014 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.014 | |
| maintenance of location | GO:0051235 | 89 | 0.014 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.014 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.014 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.013 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.013 | |
| regulation of protein binding | GO:0043393 | 60 | 0.013 | |
| cell cycle g1 s phase transition | GO:0044843 | 57 | 0.013 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.013 | |
| regulation of viral transcription | GO:0046782 | 3 | 0.013 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.013 | |
| response to ionizing radiation | GO:0010212 | 42 | 0.013 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.013 | |
| chemotaxis | GO:0006935 | 247 | 0.013 | |
| rna 3 end processing | GO:0031123 | 20 | 0.013 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.013 | |
| response to growth factor | GO:0070848 | 198 | 0.013 | |
| stem cell differentiation | GO:0048863 | 268 | 0.013 | |
| regulation of binding | GO:0051098 | 111 | 0.013 | |
| nuclear dna replication | GO:0033260 | 3 | 0.013 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.013 | |
| transmembrane transport | GO:0055085 | 412 | 0.013 | |
| gland development | GO:0048732 | 330 | 0.013 | |
| stem cell development | GO:0048864 | 219 | 0.012 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.012 | |
| male gamete generation | GO:0048232 | 285 | 0.012 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.012 | |
| spermatogenesis | GO:0007283 | 284 | 0.012 | |
| lateral inhibition | GO:0046331 | 1 | 0.012 | |
| protein targeting | GO:0006605 | 143 | 0.012 | |
| female gamete generation | GO:0007292 | 74 | 0.012 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.012 | |
| membrane organization | GO:0061024 | 245 | 0.012 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.012 | |
| sulfur compound metabolic process | GO:0006790 | 100 | 0.012 | |
| viral life cycle | GO:0019058 | 36 | 0.012 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.012 | |
| mapk cascade | GO:0000165 | 281 | 0.012 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.012 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.012 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.012 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.012 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 58 | 0.012 | |
| nucleotide excision repair | GO:0006289 | 13 | 0.012 | |
| developmental maturation | GO:0021700 | 193 | 0.012 | |
| digestive tract development | GO:0048565 | 190 | 0.012 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.012 | |
| gtp metabolic process | GO:0046039 | 144 | 0.012 | |
| protein catabolic process | GO:0030163 | 221 | 0.012 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.011 | |
| leukocyte migration | GO:0050900 | 124 | 0.011 | |
| dna modification | GO:0006304 | 50 | 0.011 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.011 | Human |
| response to oxidative stress | GO:0006979 | 123 | 0.011 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.011 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.011 | |
| b cell activation | GO:0042113 | 161 | 0.011 | |
| axon guidance | GO:0007411 | 141 | 0.011 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.011 | |
| connective tissue development | GO:0061448 | 179 | 0.011 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.011 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.011 | |
| cilium assembly | GO:0042384 | 81 | 0.011 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.011 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.011 | |
| regulation of defense response | GO:0031347 | 233 | 0.011 | |
| intracellular mrna localization | GO:0008298 | 4 | 0.011 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.011 | |
| negative regulation of multi organism process | GO:0043901 | 68 | 0.011 | |
| placenta development | GO:0001890 | 140 | 0.011 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.011 | |
| posttranscriptional gene silencing | GO:0016441 | 10 | 0.011 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.011 | |
| dna damage checkpoint | GO:0000077 | 26 | 0.010 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.010 | |
| positive regulation of viral genome replication | GO:0045070 | 2 | 0.010 | |
| protein localization to chromosome | GO:0034502 | 6 | 0.010 | Human |
| cell junction organization | GO:0034330 | 77 | 0.010 | |
| dna duplex unwinding | GO:0032508 | 7 | 0.010 | |
| internal protein amino acid acetylation | GO:0006475 | 42 | 0.010 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.010 | |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.010 | |
| regulation of receptor binding | GO:1900120 | 4 | 0.010 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.010 | |
| viral process | GO:0016032 | 41 | 0.010 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.010 | |
| positive regulation of chromatin modification | GO:1903310 | 28 | 0.010 | |