Mus musculus

147 known processes

Kdm6b

KDM1 lysine (K)-specific demethylase 6B

(Aliases: mKIAA0346,BC038313,KIAA0346,1700064E03Rik,Jmjd3)

Kdm6b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin organizationGO:00063252060.147
immune effector processGO:00022523210.105
negative regulation of immune system processGO:00026832090.099
leukocyte differentiationGO:00025213420.083
muscle cell differentiationGO:00426922610.072
negative regulation of cell proliferationGO:00082852960.071
covalent chromatin modificationGO:00165691630.068
striated muscle tissue developmentGO:00147062930.065
chromatin modificationGO:00165681870.062
adaptive immune responseGO:00022501550.062
development of primary sexual characteristicsGO:00451371430.062
Worm
macromolecule catabolic processGO:00090572810.061
cellular amine metabolic processGO:0044106440.060
cell adhesionGO:00071553290.060
gonad developmentGO:00084061410.059
Worm
gland developmentGO:00487323300.058
dorsal ventral axon guidanceGO:003356330.057
circadian rhythmGO:00076231140.057
regulation of cellular amino acid metabolic processGO:000652150.055
nucleosome disassemblyGO:000633710.055
male meiosis iGO:0007141160.053
negative regulation of t helper 2 cell differentiationGO:004562940.050
histone modificationGO:00165701590.048
developmental maturationGO:00217001930.047
nucleoside phosphate metabolic processGO:00067533380.046
developmental cell growthGO:0048588840.046
cellular ketone metabolic processGO:0042180840.046
locomotory behaviorGO:00076261950.046
skeletal system developmentGO:00015013560.045
regulation of cellular ketone metabolic processGO:0010565660.045
cell growthGO:00160491300.044
regulation of cellular catabolic processGO:00313292420.044
viral gene expressionGO:001908030.043
amine metabolic processGO:0009308450.043
lymphocyte activation involved in immune responseGO:0002285930.041
cellular response to dna damage stimulusGO:00069742070.041
regulation of cell projection organizationGO:00313442060.041
male gamete generationGO:00482322850.041
regulation of wnt signaling pathwayGO:00301111230.040
cardiac cell fate specificationGO:006091220.040
positive regulation of immune effector processGO:00026991070.039
ras protein signal transductionGO:0007265770.039
regulation of cell activationGO:00508652890.039
cellular amino acid metabolic processGO:00065201030.038
regulation of protein catabolic processGO:00421761080.038
meiotic cell cycleGO:00513211220.037
peptidyl amino acid modificationGO:00181933360.037
single organism cell adhesionGO:00986021560.037
negative regulation of protein metabolic processGO:00512482820.037
hepaticobiliary system developmentGO:0061008670.036
t cell differentiationGO:00302171740.036
t cell activationGO:00421102890.036
central nervous system neuron differentiationGO:00219531620.036
lymphocyte differentiationGO:00300982420.036
digestive system developmentGO:00551232000.035
regulation of organelle organizationGO:00330432890.035
molting cycleGO:0042303900.035
response to organonitrogen compoundGO:00102432460.034
dendrite developmentGO:00163581150.034
negative regulation of wnt signaling pathwayGO:0030178730.034
regionalizationGO:00030023370.033
Mouse
interspecies interaction between organismsGO:0044419830.033
rhythmic processGO:00485111740.033
cell fate commitmentGO:00451652100.033
spermatogenesisGO:00072832840.033
regulation of lymphocyte activationGO:00512492400.033
cellular nitrogen compound catabolic processGO:00442702800.032
mammary gland morphogenesisGO:0060443540.032
skeletal muscle organ developmentGO:00605381630.032
developmental growth involved in morphogenesisGO:00605601380.032
ribose phosphate metabolic processGO:00196932910.032
cellular homeostasisGO:00197252400.031
nucleoside triphosphate metabolic processGO:00091412300.031
rho protein signal transductionGO:0007266320.031
positive regulation of cellular amine metabolic processGO:003324050.031
leukocyte activation involved in immune responseGO:00023661260.031
regulation of neuron differentiationGO:00456642810.031
cellular response to organonitrogen compoundGO:00714171450.031
cellular macromolecule catabolic processGO:00442652060.030
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.030
positive regulation of growthGO:00459271040.030
Worm
negative regulation of cellular component organizationGO:00511291940.030
regulation of cell migrationGO:00303342190.030
nucleoside phosphate catabolic processGO:19012922220.030
feeding behaviorGO:0007631620.030
chromatin disassemblyGO:003149810.029
purine nucleotide metabolic processGO:00061633020.029
organonitrogen compound catabolic processGO:19015652640.029
regulation of cellular amine metabolic processGO:0033238200.029
epidermis developmentGO:00085441870.029
purine containing compound metabolic processGO:00725213110.029
regulation of cell motilityGO:20001452360.029
mitotic cell cycleGO:00002781950.029
purine nucleotide catabolic processGO:00061952110.029
forebrain developmentGO:00309003020.028
actin cytoskeleton organizationGO:00300362200.028
negative regulation of cellular protein metabolic processGO:00322692470.028
positive regulation of nervous system developmentGO:00519622210.028
negative regulation of cell activationGO:00508661110.028
regulation of cell cycleGO:00517262810.028
negative regulation of leukocyte differentiationGO:1902106510.028
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.028
organic cyclic compound catabolic processGO:19013612950.027
nucleoside metabolic processGO:00091162460.027
myotube differentiationGO:00149021050.027
positive regulation of organelle organizationGO:00106381280.027
regulation of cellular component biogenesisGO:00440871810.027
viral transcriptionGO:001908330.027
regulation of cell adhesionGO:00301551540.026
cellular protein catabolic processGO:00442571550.026
regulation of cellular response to stressGO:00801351590.026
purine nucleoside metabolic processGO:00422782410.026
small gtpase mediated signal transductionGO:0007264970.026
regulation of anatomical structure sizeGO:00900661780.026
purine ribonucleotide metabolic processGO:00091502900.026
myeloid cell differentiationGO:00300992330.026
reactive oxygen species metabolic processGO:0072593840.026
regulation of adaptive immune responseGO:0002819900.026
purine nucleoside catabolic processGO:00061522050.026
regulation of defense responseGO:00313472330.026
positive regulation of cellular component biogenesisGO:0044089940.026
positive regulation of cell activationGO:00508671580.025
negative regulation of molecular functionGO:00440922580.025
dna metabolic processGO:00062593030.025
ribonucleoside metabolic processGO:00091192450.025
aromatic compound catabolic processGO:00194392860.025
nucleobase containing small molecule metabolic processGO:00550863520.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
regulation of neuron projection developmentGO:00109751690.025
cell activation involved in immune responseGO:00022631260.025
meiosis iGO:0007127600.025
spleen developmentGO:0048536390.025
cellular lipid metabolic processGO:00442553230.024
protein methylationGO:0006479810.024
Worm
homeostasis of number of cellsGO:00488722100.024
nucleotide metabolic processGO:00091173320.024
maintenance of locationGO:0051235890.024
neural tube developmentGO:00219151600.024
Mouse
digestive tract developmentGO:00485651900.024
apoptotic signaling pathwayGO:00971903060.024
skeletal system morphogenesisGO:00487052030.024
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.024
protein ubiquitinationGO:00165671710.024
proteolysis involved in cellular protein catabolic processGO:00516031470.024
negative regulation of nervous system developmentGO:00519611560.024
rna processingGO:00063961050.024
muscle tissue developmentGO:00605373080.023
negative regulation of phosphorylationGO:00423261660.023
organophosphate catabolic processGO:00464342320.023
innate immune responseGO:00450871570.023
erythrocyte differentiationGO:0030218880.023
embryonic organ morphogenesisGO:00485622760.023
Mouse
negative regulation of protein modification processGO:00314001630.023
protein modification by small protein conjugationGO:00324461870.022
meiotic nuclear divisionGO:00071261150.022
ossificationGO:00015032160.022
chemotaxisGO:00069352470.022
mammary gland epithelium developmentGO:0061180650.022
proteasomal protein catabolic processGO:0010498980.022
renal system developmentGO:00720012250.022
regulation of reactive oxygen species metabolic processGO:2000377400.022
glycosyl compound metabolic processGO:19016572460.022
protein dna complex disassemblyGO:003298610.022
multicellular organism growthGO:00352641610.022
Mouse Worm
regulation of cellular protein catabolic processGO:1903362610.022
negative regulation of immune effector processGO:0002698550.022
positive regulation of leukocyte differentiationGO:1902107860.022
macromolecule methylationGO:00434141200.022
Worm
negative regulation of phosphate metabolic processGO:00459361840.022
actin filament organizationGO:00070151130.021
nuclear divisionGO:00002801580.021
ribonucleoside catabolic processGO:00424542060.021
regulation of cytokine productionGO:00018172660.021
cartilage developmentGO:00512161400.021
regulation of circadian rhythmGO:0042752580.021
microtubule based processGO:00070172360.021
lateral inhibitionGO:004633110.021
alpha beta t cell differentiation involved in immune responseGO:0002293300.021
stem cell differentiationGO:00488632680.021
response to peptideGO:19016521360.021
axonogenesisGO:00074092740.021
neuron migrationGO:00017641220.021
carbohydrate derivative catabolic processGO:19011362310.021
regulation of cd4 positive alpha beta t cell activationGO:2000514240.021
purine ribonucleoside catabolic processGO:00461302050.020
regulation of actin filament based processGO:0032970990.020
myeloid cell homeostasisGO:00022621140.020
blood vessel morphogenesisGO:00485142850.020
single organismal cell cell adhesionGO:00163371310.020
protein catabolic processGO:00301632210.020
nucleoside triphosphate catabolic processGO:00091432050.020
viral processGO:0016032410.020
positive regulation of alpha beta t cell differentiationGO:0046638280.020
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
negative regulation of cell developmentGO:00107211690.020
regulation of hormone levelsGO:00108172110.020
heart morphogenesisGO:00030071780.020
Mouse
pole plasm assemblyGO:000731520.019
kidney developmentGO:00018222130.019
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.019
epithelial tube morphogenesisGO:00605623030.019
Mouse
posttranscriptional regulation of gene expressionGO:00106081550.019
telencephalon developmentGO:00215371860.019
regulation of mapk cascadeGO:00434082480.019
negative regulation of protein phosphorylationGO:00019331260.019
cognitionGO:00508901490.019
actin filament polymerizationGO:0030041440.019
positive regulation of t cell activationGO:00508701010.019
nucleotide catabolic processGO:00091662170.019
regulation of proteolysisGO:00301621640.019
positive regulation of cell developmentGO:00107202370.019
purine ribonucleoside metabolic processGO:00461282410.019
positive regulation of protein modification processGO:00314012990.019
regulation of system processGO:00440572000.019
neuromuscular processGO:0050905990.019
microtubule cytoskeleton organizationGO:00002261570.018
purine nucleoside triphosphate metabolic processGO:00091442260.018
regulation of multi organism processGO:00439001110.018
regulation of mitotic cell cycleGO:00073461260.018
positive regulation of cellular catabolic processGO:00313311480.018
neuron projection extensionGO:1990138640.018
carbohydrate metabolic processGO:00059752300.018
regulation of viral transcriptionGO:004678230.018
positive regulation of protein catabolic processGO:0045732600.018
peptidyl lysine modificationGO:0018205770.018
modification dependent protein catabolic processGO:00199411330.018
histone methylationGO:0016571710.018
methylationGO:00322591340.018
Worm
carbohydrate derivative biosynthetic processGO:19011371830.018
actin polymerization or depolymerizationGO:0008154540.018
sensory perceptionGO:00076002450.018
neuron deathGO:00709971540.018
cell recognitionGO:0008037830.018
positive regulation of adaptive immune responseGO:0002821610.018
cardiocyte differentiationGO:0035051870.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
mapk cascadeGO:00001652810.018
organelle fissionGO:00482851700.017
negative regulation of intracellular signal transductionGO:19025321670.017
purine nucleoside triphosphate catabolic processGO:00091462030.017
mitotic cell cycle processGO:19030471590.017
regulation of cell cycle processGO:00105641600.017
alpha beta t cell differentiationGO:0046632690.017
regulation of lymphocyte differentiationGO:00456191070.017
purine containing compound catabolic processGO:00725232130.017
cellular protein complex assemblyGO:00436231160.017
regulation of transferase activityGO:00513382630.017
forebrain generation of neuronsGO:0021872630.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.017
negative regulation of cell cycleGO:00457861230.017
regulation of cytoskeleton organizationGO:00514931220.017
regulation of kinase activityGO:00435492490.017
blastocyst developmentGO:0001824800.017
camera type eye developmentGO:00430102660.017
oocyte constructionGO:000730820.017
oxidation reduction processGO:00551143420.017
Mouse
regulation of t cell differentiationGO:0045580830.017
cell type specific apoptotic processGO:00972852680.017
ubiquitin dependent protein catabolic processGO:00065111290.017
regulation of body fluid levelsGO:00508781620.017
canonical wnt signaling pathwayGO:00600701300.017
Mouse
anatomical structure homeostasisGO:00602491450.016
mrna metabolic processGO:0016071840.016
mitotic cytokinesisGO:000028140.016
regulation of protein kinase activityGO:00458592320.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
protein maturationGO:00516041760.016
regulation of response to woundingGO:19030341890.016
compound eye developmentGO:004874910.016
positive regulation of purine nucleotide metabolic processGO:19005441140.016
regulation of hydrolase activityGO:00513362460.016
positive regulation of cell adhesionGO:0045785800.016
motor neuron axon guidanceGO:0008045260.016
wnt signaling pathwayGO:00160551880.016
Mouse
endocytosisGO:00068971680.015
cation transportGO:00068123990.015
epithelial cell developmentGO:00020641590.015
modification dependent macromolecule catabolic processGO:00436321330.015
negative regulation of lymphocyte activationGO:0051250910.015
dephosphorylationGO:00163111290.015
response to organic cyclic compoundGO:00140701980.015
purine ribonucleotide catabolic processGO:00091542080.015
response to peptide hormoneGO:00434341270.015
positive regulation of t cell differentiationGO:0045582520.015
gliogenesisGO:00420631410.015
negative regulation of phosphorus metabolic processGO:00105631840.015
ribonucleotide catabolic processGO:00092612080.015
organonitrogen compound biosynthetic processGO:19015661920.015
regulation of nucleotide catabolic processGO:00308111220.015
extracellular structure organizationGO:00430621480.015
sensory system developmentGO:004888030.015
hematopoietic progenitor cell differentiationGO:00022441430.015
liver developmentGO:0001889660.015
response to molecule of bacterial originGO:00022371430.015
ribonucleoside triphosphate catabolic processGO:00092031990.015
regulation of alpha beta t cell differentiationGO:0046637350.015
neuron projection guidanceGO:00974851410.015
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.015
meiotic cell cycle processGO:1903046770.014
regulation of actin cytoskeleton organizationGO:0032956840.014
regulation of proteasomal protein catabolic processGO:0061136460.014
response to acid chemicalGO:00011011110.014
neural precursor cell proliferationGO:00613511210.014
ameboidal type cell migrationGO:00016671280.014
regulation of protein serine threonine kinase activityGO:00719001570.014
fat cell differentiationGO:00454441600.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
body morphogenesisGO:0010171450.014
ribonucleotide metabolic processGO:00092592910.014
regulation of protein maturationGO:1903317960.014
oocyte axis specificationGO:000730920.014
anatomical structure maturationGO:0071695490.014
t cell proliferationGO:00420981200.014
t cell activation involved in immune responseGO:0002286430.014
regulation of nucleotide metabolic processGO:00061401690.014
negative regulation of cell motilityGO:2000146610.014
regulation of neuron apoptotic processGO:00435231220.014
cell divisionGO:00513011200.014
alpha beta t cell activationGO:0046631910.014
t helper 1 type immune responseGO:0042088250.014
maternal determination of anterior posterior axis embryoGO:000835820.014
protein acylationGO:0043543640.014
regulation of actin nucleationGO:005112540.014
heterocycle catabolic processGO:00467002800.013
negative regulation of t cell activationGO:0050868650.013
glycosyl compound catabolic processGO:19016582060.013
viral life cycleGO:0019058360.013
regulation of inflammatory responseGO:00507271470.013
regulation of protein localizationGO:00328802310.013
regulation of organ growthGO:0046620610.013
negative regulation of cellular amine metabolic processGO:003323910.013
regulation of cell growthGO:0001558910.013
muscle system processGO:00030121410.013
Mouse
central nervous system neuron developmentGO:0021954670.013
urogenital system developmentGO:00016552610.013
exocrine system developmentGO:0035272450.013
leukocyte proliferationGO:00706611720.013
autonomic nervous system developmentGO:0048483430.013
regulation of bindingGO:00510981110.013
hair cycleGO:0042633900.013
positive regulation of cell deathGO:00109422240.013
negative regulation of lymphocyte differentiationGO:0045620320.013
stem cell proliferationGO:00720891170.013
angiogenesisGO:00015252010.013
regulation of nucleoside metabolic processGO:00091181300.013
regulation of purine nucleotide metabolic processGO:19005421690.013
cellular response to hormone stimulusGO:00328701500.013
negative regulation of proteolysisGO:0045861740.013
regulation of secretionGO:00510462740.013
intrinsic apoptotic signaling pathwayGO:00971931320.013
regulation of leukocyte differentiationGO:19021051590.013
organic hydroxy compound metabolic processGO:19016152030.013
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.013
response to insulinGO:00328681000.013
mrna processingGO:0006397630.012
regulation of apoptotic signaling pathwayGO:20012331970.012
cellular response to cytokine stimulusGO:00713451890.012
chromatin assembly or disassemblyGO:0006333160.012
regulation of t cell activationGO:00508631700.012
cation transmembrane transportGO:00986552660.012
cellular chemical homeostasisGO:00550822150.012
cellular carbohydrate metabolic processGO:00442621190.012
wound healingGO:00420601570.012
regulation of purine nucleotide catabolic processGO:00331211220.012
nuclear transportGO:00511691390.012
regulation of rho protein signal transductionGO:0035023710.012
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.012
chromosome segregationGO:0007059480.012
positive regulation of alpha beta t cell activationGO:0046635390.012
negative regulation of t cell differentiationGO:0045581230.012
nucleocytoplasmic transportGO:00069131390.012
negative regulation of synapse assemblyGO:005196430.012
cellular response to peptide hormone stimulusGO:0071375920.012
regulation of protein processingGO:0070613960.012
negative regulation of organelle organizationGO:0010639900.012
respiratory tube developmentGO:00303231670.012
regulation of cell cycle phase transitionGO:1901987770.012
gtp metabolic processGO:00460391440.012
respiratory system developmentGO:00605411900.012
myosin filament assemblyGO:003103420.012
response to inorganic substanceGO:0010035960.012
learning or memoryGO:00076111480.012
neuron apoptotic processGO:00514021420.012
protein alkylationGO:0008213810.012
Worm
axon guidanceGO:00074111410.012
regulation of alpha beta t cell activationGO:0046634530.012
positive regulation of protein kinase activityGO:00458601440.012
histone lysine methylationGO:0034968500.012
negative regulation of protein processingGO:0010955790.012
bone developmentGO:00603481200.012
immune response regulating signaling pathwayGO:00027641250.012
positive regulation of gtpase activityGO:0043547850.012
rna interferenceGO:001624620.012
regulation of gtp catabolic processGO:00331241130.012
positive regulation of apoptotic processGO:00430652170.012
germ cell developmentGO:00072811850.012
Worm
oocyte anterior posterior axis specificationGO:000731420.012
morphogenesis of a branching epitheliumGO:00611381930.012
positive regulation of transferase activityGO:00513471670.012
protein processingGO:00164851630.012
positive regulation of cell projection organizationGO:0031346950.012
negative regulation of protein maturationGO:1903318790.012
organelle localizationGO:00516401790.012
myeloid leukocyte differentiationGO:00025731190.012
cation homeostasisGO:00550802120.012
generation of precursor metabolites and energyGO:00060911030.012
epithelial tube formationGO:00721751300.012
Mouse
outflow tract morphogenesisGO:0003151530.012
rna splicingGO:0008380540.011
pallium developmentGO:00215431200.011
regulation of stem cell proliferationGO:0072091780.011
cytokine productionGO:00018163190.011
gtp catabolic processGO:00061841430.011
negative regulation of multi organism processGO:0043901680.011
g protein coupled receptor signaling pathwayGO:00071862430.011
negative regulation of kinase activityGO:0033673810.011
placenta developmentGO:00018901400.011
regulation of ossificationGO:00302781120.011
positive regulation of viral entry into host cellGO:004659830.011
limb morphogenesisGO:00351081490.011
histone acetylationGO:0016573410.011
positive regulation of viral processGO:004852450.011
cytoplasmic transportGO:00164822340.011
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.011
cd4 positive alpha beta t cell activationGO:0035710450.011
cardiac chamber developmentGO:00032051080.011
negative regulation of viral transcriptionGO:003289730.011
intracellular protein transportGO:00068862040.011
leukocyte mediated immunityGO:00024431740.011
asymmetric stem cell divisionGO:009872230.011
salivary gland developmentGO:0007431370.011
hair cycle phaseGO:0044851160.011
regulation of protein complex assemblyGO:0043254830.011
hindbrain developmentGO:00309021280.011
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.011
regulation of t helper cell differentiationGO:0045622140.011
symbiosis encompassing mutualism through parasitismGO:0044403830.011
synaptic transmissionGO:00072683290.011
cd4 positive alpha beta t cell differentiationGO:0043367410.011
protein polymerizationGO:0051258570.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.011
neuron recognitionGO:0008038250.011
response to growth factorGO:00708481980.011
stress activated mapk cascadeGO:0051403800.011
cardiac muscle tissue developmentGO:00487381300.011
multicellular organismal homeostasisGO:00488711640.010
positive regulation of actin nucleationGO:005112730.010
lipid biosynthetic processGO:00086101790.010
positive regulation of kinase activityGO:00336741550.010
tube closureGO:0060606910.010
Mouse
osteoclast differentiationGO:0030316620.010
protein localization to organelleGO:00333651850.010
protein modification by small protein conjugation or removalGO:00706472070.010
regulation of neuron deathGO:19012141340.010
regulation of ras protein signal transductionGO:00465781140.010
regulation of innate immune responseGO:0045088910.010
ventral spinal cord developmentGO:0021517480.010
negative regulation of cell cycle processGO:0010948690.010
nucleoside catabolic processGO:00091642060.010
regulation of secretion by cellGO:19035302490.010
dna methylationGO:0006306430.010
regulation of cellular component sizeGO:00325351210.010
intracellular mrna localizationGO:000829840.010
hormone secretionGO:00468791280.010
tissue homeostasisGO:00018941150.010
rna splicing via transesterification reactionsGO:0000375430.010
cellular response to insulin stimulusGO:0032869780.010
cell substrate adhesionGO:00315891300.010

Kdm6b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.022
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.019
organ system cancerDOID:005068600.013
cancerDOID:16200.013
disease of metabolismDOID:001466700.010