Mus musculus

0 known processes

Prpf8

pre-mRNA processing factor 8

(Aliases: DBF3/PRP8,Sfprp8l,AU019467,Prp8,D11Bwg0410e)

Prpf8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
covalent chromatin modificationGO:00165691630.558
chromatin organizationGO:00063252060.248
protein modification by small protein conjugation or removalGO:00706472070.223
histone modificationGO:00165701590.170
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.163
cellular response to dna damage stimulusGO:00069742070.157
dna metabolic processGO:00062593030.141
positive regulation of dna templated transcription elongationGO:003278620.137
protein methylationGO:0006479810.126
protein ubiquitinationGO:00165671710.120
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.115
Human Fly
chromatin modificationGO:00165681870.111
dna alkylationGO:0006305430.096
purine nucleoside catabolic processGO:00061522050.089
mrna metabolic processGO:0016071840.089
Human Fly
protein modification by small protein removalGO:0070646210.082
regulation of cell cycleGO:00517262810.080
histone methylationGO:0016571710.079
methylationGO:00322591340.078
peptidyl lysine modificationGO:0018205770.077
intracellular protein transportGO:00068862040.075
macromolecule methylationGO:00434141200.074
nuclear exportGO:0051168340.072
chromatin disassemblyGO:003149810.071
epithalamus developmentGO:002153820.069
peptidyl amino acid modificationGO:00181933360.068
histone deubiquitinationGO:001657820.067
autophagyGO:0006914450.066
tube closureGO:0060606910.065
heterocycle catabolic processGO:00467002800.065
organonitrogen compound catabolic processGO:19015652640.064
regulation of chromatin modificationGO:1903308570.063
intracellular receptor signaling pathwayGO:0030522740.062
regulation of cellular ketone metabolic processGO:0010565660.061
rna splicingGO:0008380540.060
Human Fly
immune effector processGO:00022523210.060
intracellular steroid hormone receptor signaling pathwayGO:0030518290.059
stem cell maintenanceGO:00198271300.058
innate immune responseGO:00450871570.057
carbohydrate derivative catabolic processGO:19011362310.056
cellular ketone metabolic processGO:0042180840.056
regulation of organelle organizationGO:00330432890.053
positive regulation of protein modification processGO:00314012990.051
regulation of histone modificationGO:0031056560.051
regulation of chromatin silencingGO:003193520.050
symbiosis encompassing mutualism through parasitismGO:0044403830.050
protein processingGO:00164851630.050
ribonucleotide catabolic processGO:00092612080.050
stem cell developmentGO:00488642190.050
response to nutrient levelsGO:00316671090.049
regulation of myeloid leukocyte differentiationGO:0002761580.049
rna processingGO:00063961050.049
Human Fly
posttranscriptional regulation of gene expressionGO:00106081550.048
macromolecular complex disassemblyGO:0032984430.047
misfolded protein transportGO:007084310.046
regulation of response to alcoholGO:190141920.046
nucleocytoplasmic transportGO:00069131390.045
purine nucleoside triphosphate metabolic processGO:00091442260.045
response to radiationGO:00093141650.045
dna repairGO:00062811070.044
histone h4 acetylationGO:0043967100.044
defense response to bacteriumGO:00427421190.043
glycosyl compound metabolic processGO:19016572460.043
gland developmentGO:00487323300.040
cellular amino acid metabolic processGO:00065201030.040
dna methylationGO:0006306430.039
regulation of cell cycle checkpointGO:190197690.039
action potentialGO:0001508780.039
regulation of protein serine threonine kinase activityGO:00719001570.038
astral microtubule organizationGO:003095330.038
protein modification by small protein conjugationGO:00324461870.038
response to extracellular stimulusGO:00099911270.037
ribose phosphate metabolic processGO:00196932910.037
positive regulation of histone methylationGO:0031062160.037
nuclear transportGO:00511691390.036
stem cell differentiationGO:00488632680.036
cellular nitrogen compound catabolic processGO:00442702800.036
dendrite developmentGO:00163581150.036
modification dependent protein catabolic processGO:00199411330.035
nucleic acid transportGO:0050657180.035
wnt signaling pathwayGO:00160551880.035
regulation of chromosome organizationGO:0033044830.034
cytoplasmic transportGO:00164822340.034
amine metabolic processGO:0009308450.034
cellular amine metabolic processGO:0044106440.034
blastocyst developmentGO:0001824800.033
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.033
primary neural tube formationGO:0014020950.032
purine ribonucleoside catabolic processGO:00461302050.032
maintenance of locationGO:0051235890.032
copii coated vesicle buddingGO:009011420.031
gonad developmentGO:00084061410.031
Worm
purine containing compound metabolic processGO:00725213110.031
aromatic compound catabolic processGO:00194392860.031
transcription from rna polymerase iii promoterGO:000638330.031
transmission of nerve impulseGO:0019226760.031
microtubule cytoskeleton organizationGO:00002261570.031
regulation of chromatin organizationGO:1902275570.031
mrna transportGO:0051028130.030
negative regulation of synapse assemblyGO:005196430.030
defense response to other organismGO:00985421970.030
negative regulation of cellular protein metabolic processGO:00322692470.030
purine containing compound catabolic processGO:00725232130.029
regulation of cell morphogenesis involved in differentiationGO:00107691510.029
vitamin d receptor signaling pathwayGO:007056120.029
regulation of antimicrobial humoral responseGO:000275930.028
negative regulation of cellular component organizationGO:00511291940.028
regulation of wnt signaling pathwayGO:00301111230.028
nuclear divisionGO:00002801580.028
axon ensheathmentGO:0008366760.027
regulation of mrna metabolic processGO:1903311430.027
ossificationGO:00015032160.027
protein targetingGO:00066051430.027
regulation of myeloid cell differentiationGO:0045637960.027
positive regulation of neuron projection developmentGO:0010976790.027
protein oligomerizationGO:0051259670.027
cognitionGO:00508901490.026
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.026
dna modificationGO:0006304500.026
morphogenesis of embryonic epitheliumGO:00163311590.026
nucleobase containing small molecule metabolic processGO:00550863520.026
myeloid leukocyte differentiationGO:00025731190.026
neural tube developmentGO:00219151600.025
ribonucleoside monophosphate catabolic processGO:0009158570.025
gliogenesisGO:00420631410.025
positive regulation of protein phosphorylationGO:00019342420.025
regulation of mitotic cell cycle phase transitionGO:1901990730.025
nucleotide catabolic processGO:00091662170.024
negative regulation of protein metabolic processGO:00512482820.024
blastocyst growthGO:0001832230.024
regulation of cell cycle processGO:00105641600.024
ensheathment of neuronsGO:0007272760.024
regulation of rna splicingGO:0043484370.024
histone h4 k16 acetylationGO:004398430.023
nucleoside triphosphate catabolic processGO:00091432050.023
regulation of protein localizationGO:00328802310.023
fat cell differentiationGO:00454441600.023
protein maturationGO:00516041760.023
localization within membraneGO:005166840.023
glial cell differentiationGO:00100011310.023
regulation of neuron projection developmentGO:00109751690.023
protein deubiquitinationGO:0016579190.022
negative regulation of molecular functionGO:00440922580.022
nucleotide metabolic processGO:00091173320.022
regulation of map kinase activityGO:00434051200.022
positive regulation of antibacterial peptide biosynthetic processGO:000696310.022
skeletal system developmentGO:00015013560.022
response to organic cyclic compoundGO:00140701980.022
cytoplasmic translational initiationGO:000218330.021
cellular response to external stimulusGO:0071496880.021
protein alkylationGO:0008213810.021
mrna export from nucleusGO:0006406110.021
negative regulation of cell proliferationGO:00082852960.021
positive regulation of chromosome organizationGO:2001252330.021
purine ribonucleotide catabolic processGO:00091542080.021
myeloid cell differentiationGO:00300992330.021
synaptonemal complex assemblyGO:0007130130.021
chemotaxisGO:00069352470.021
transcription coupled nucleotide excision repairGO:000628320.021
developmental growth involved in morphogenesisGO:00605601380.020
regulation of protein stabilityGO:0031647520.020
meiotic nuclear divisionGO:00071261150.020
regulation of protein complex assemblyGO:0043254830.020
negative regulation of protein maturationGO:1903318790.020
positive regulation of defense response to bacteriumGO:190042610.020
rna localizationGO:0006403230.020
regulation of cell divisionGO:0051302760.020
neural tube closureGO:0001843900.019
ribonucleoside catabolic processGO:00424542060.019
regulation of histone methylationGO:0031060300.019
multi multicellular organism processGO:00447061090.019
regulation of neuron differentiationGO:00456642810.019
rhythmic processGO:00485111740.019
receptor biosynthetic processGO:003280030.019
regulation of cell substrate adhesionGO:0010810730.019
regulation of lymphocyte activationGO:00512492400.019
regulation of cell projection organizationGO:00313442060.019
dna templated transcription elongationGO:0006354130.019
ribonucleoprotein complex subunit organizationGO:0071826280.018
Human
defense response to virusGO:0051607680.018
lymphocyte differentiationGO:00300982420.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
negative regulation of proteolysisGO:0045861740.018
positive regulation of programmed cell deathGO:00430682180.018
nucleoside metabolic processGO:00091162460.018
epithelial tube formationGO:00721751300.018
regulation of establishment of protein localizationGO:00702011810.018
response to endoplasmic reticulum stressGO:0034976530.018
negative regulation of cell sizeGO:004579230.018
glial cell developmentGO:0021782540.018
cellular response to starvationGO:0009267570.018
regulation of cellular carbohydrate metabolic processGO:0010675750.018
response to growth factorGO:00708481980.018
atp metabolic processGO:0046034750.018
positive regulation of histone modificationGO:0031058280.018
carbohydrate biosynthetic processGO:0016051740.017
embryonic skeletal system developmentGO:00487061200.017
microtubule nucleationGO:000702020.017
lipid localizationGO:00108761260.017
establishment of rna localizationGO:0051236180.017
homeostasis of number of cellsGO:00488722100.017
regulation of multi organism processGO:00439001110.017
response to inorganic substanceGO:0010035960.017
positive regulation of nucleocytoplasmic transportGO:0046824300.017
memoryGO:0007613580.017
leukocyte differentiationGO:00025213420.017
myelinationGO:0042552740.017
nucleoside monophosphate catabolic processGO:0009125590.016
regulation of cellular amino acid metabolic processGO:000652150.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
ribonucleoprotein complex disassemblyGO:003298830.016
endomembrane system organizationGO:00102561470.016
somite developmentGO:0061053810.016
cellular hyperosmotic salinity responseGO:007147500.016
embryonic epithelial tube formationGO:00018381300.016
multicellular organismal homeostasisGO:00488711640.016
regulation of dna templated transcription elongationGO:0032784100.016
regulation of transcription by chromatin organizationGO:003440100.016
positive regulation of defense responseGO:00313491240.016
ribonucleoside triphosphate catabolic processGO:00092031990.016
meiotic cell cycleGO:00513211220.016
cellular response to extracellular stimulusGO:0031668810.016
tube formationGO:00351481400.016
nucleoside phosphate catabolic processGO:19012922220.016
regulation of glucose metabolic processGO:0010906600.016
renal system developmentGO:00720012250.016
antimicrobial peptide productionGO:000277520.016
multicellular organismal signalingGO:0035637910.015
mrna splicing via spliceosomeGO:0000398430.015
Human Fly
cell junction organizationGO:0034330770.015
cell fate determination involved in pattern specificationGO:006058210.015
dna templated transcription initiationGO:0006352130.015
establishment of protein localization to organelleGO:00725941180.015
hindbrain developmentGO:00309021280.015
axis elongationGO:0003401300.015
regulation of cellular amine metabolic processGO:0033238200.015
protein import into nucleusGO:0006606950.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
response to light stimulusGO:00094161350.015
spermatid differentiationGO:00485151150.015
nucleoside monophosphate metabolic processGO:0009123850.015
neural tube formationGO:00018411080.015
response to acid chemicalGO:00011011110.015
positive regulation of immune effector processGO:00026991070.015
regulation of cell activationGO:00508652890.015
cellular protein complex disassemblyGO:0043624360.015
membrane organizationGO:00610242450.015
intracellular mrna localizationGO:000829840.015
positive regulation of neuron differentiationGO:00456661410.015
organic cyclic compound catabolic processGO:19013612950.015
nucleoside phosphate metabolic processGO:00067533380.014
trna wobble uridine modificationGO:000209820.014
cellular protein complex assemblyGO:00436231160.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
male gamete generationGO:00482322850.014
rna splicing via transesterification reactionsGO:0000375430.014
Human Fly
lipid storageGO:0019915360.014
positive regulation of chromatin modificationGO:1903310280.014
regulation of antimicrobial peptide productionGO:000278410.014
ameboidal type cell migrationGO:00016671280.014
regulation of carbohydrate metabolic processGO:0006109750.014
cell cycle arrestGO:0007050370.014
mesenchyme developmentGO:00604851520.014
positive regulation of hydrolase activityGO:00513451480.014
negative regulation of neuron deathGO:1901215980.014
regulation of t cell activationGO:00508631700.014
mitotic cell cycleGO:00002781950.014
rna transportGO:0050658180.014
synapsisGO:0007129340.013
ncrna 3 end processingGO:004362820.013
protein complex disassemblyGO:0043241400.013
positive regulation of growthGO:00459271040.013
cell fate commitmentGO:00451652100.013
digestive system developmentGO:00551232000.013
negative regulation of cellular amine metabolic processGO:003323910.013
neuron deathGO:00709971540.013
cytokine productionGO:00018163190.013
regulation of mrna processingGO:0050684410.013
positive regulation of histone h3 k4 methylationGO:005157150.013
cellular response to nutrient levelsGO:0031669640.013
protein localization to organelleGO:00333651850.013
regulation of cellular component biogenesisGO:00440871810.013
regulation of homeostatic processGO:00328441820.013
regulation of response to biotic stimulusGO:0002831380.013
purine nucleoside metabolic processGO:00422782410.013
purine ribonucleoside metabolic processGO:00461282410.013
response to starvationGO:0042594650.013
somitogenesisGO:0001756690.013
dephosphorylationGO:00163111290.013
negative regulation of neuron apoptotic processGO:0043524920.013
positive regulation of protein serine threonine kinase activityGO:00719021060.013
ribonucleotide metabolic processGO:00092592910.013
positive regulation of apoptotic processGO:00430652170.013
adult locomotory behaviorGO:0008344910.013
oligodendrocyte differentiationGO:0048709530.013
ubiquitin dependent protein catabolic processGO:00065111290.013
liver developmentGO:0001889660.013
cellular response to growth factor stimulusGO:00713631970.013
regulation of antimicrobial peptide biosynthetic processGO:000280510.013
response to reactive oxygen speciesGO:0000302560.013
response to temperature stimulusGO:0009266550.012
skeletal system morphogenesisGO:00487052030.012
regulation of neuron deathGO:19012141340.012
changes to dna methylation involved in embryo developmentGO:190153860.012
cellular response to lipidGO:00713961450.012
anatomical structure homeostasisGO:00602491450.012
placenta developmentGO:00018901400.012
organelle assemblyGO:00709251770.012
nucleoside catabolic processGO:00091642060.012
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.012
cell recognitionGO:0008037830.012
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.012
positive regulation of wnt signaling pathwayGO:0030177450.012
response to sterolGO:003631440.012
axonogenesisGO:00074092740.012
regulation of protein import into nucleusGO:0042306520.012
protein catabolic processGO:00301632210.012
segmentationGO:0035282930.012
regulation of protein kinase activityGO:00458592320.012
single fertilizationGO:0007338820.012
neuronal action potentialGO:0019228540.012
axis elongation involved in somitogenesisGO:009024540.012
nucleoside triphosphate metabolic processGO:00091412300.012
epithelial cell developmentGO:00020641590.012
regulation of hydrolase activityGO:00513362460.012
viral life cycleGO:0019058360.012
viral processGO:0016032410.012
positive regulation of cellular amine metabolic processGO:003324050.012
habenula developmentGO:002198620.011
regulation of proteolysisGO:00301621640.011
interspecies interaction between organismsGO:0044419830.011
purine nucleotide catabolic processGO:00061952110.011
cell adhesionGO:00071553290.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
epithelial tube morphogenesisGO:00605623030.011
regulation of rna export from nucleusGO:004683140.011
spermatogenesisGO:00072832840.011
positive regulation of nervous system developmentGO:00519622210.011
positive regulation of organelle organizationGO:00106381280.011
regulation of mrna splicing via spliceosomeGO:0048024320.011
activation of mapkkk activityGO:000018510.011
spliceosomal complex disassemblyGO:000039010.011
positive regulation of cell deathGO:00109422240.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
ribonucleoside metabolic processGO:00091192450.011
positive regulation of cell developmentGO:00107202370.011
positive regulation of lymphocyte activationGO:00512511400.011
internal protein amino acid acetylationGO:0006475420.011
cellular response to organic cyclic compoundGO:0071407870.011
histone lysine methylationGO:0034968500.011
protein acylationGO:0043543640.011
blood circulationGO:00080151950.011
regulation of neural precursor cell proliferationGO:2000177700.011
ectoderm formationGO:000170530.011
regulation of dna damage checkpointGO:200000130.011
embryonic organ morphogenesisGO:00485622760.011
positive regulation of intracellular transportGO:0032388700.011
regulation of cell motilityGO:20001452360.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
skin developmentGO:00435882200.011
gtp metabolic processGO:00460391440.011
neural precursor cell proliferationGO:00613511210.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.010
negative regulation of androgen receptor signaling pathwayGO:006076630.010
positive regulation of intracellular protein transportGO:0090316420.010
urogenital system developmentGO:00016552610.010
forebrain developmentGO:00309003020.010
single organism nuclear importGO:1902593950.010
response to uvGO:0009411440.010
blastocyst hatchingGO:000183540.010
connective tissue developmentGO:00614481790.010
embryonic skeletal system morphogenesisGO:0048704910.010
sensory perceptionGO:00076002450.010
mitotic cell cycle processGO:19030471590.010
positive regulation of cell cycle processGO:0090068610.010
muscle cell differentiationGO:00426922610.010
dna dealkylationGO:0035510110.010
regulation of antibacterial peptide biosynthetic processGO:000280810.010
positive regulation of cell projection organizationGO:0031346950.010

Prpf8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.025
Human
disease of anatomical entityDOID:700.025
Human
central nervous system diseaseDOID:33100.023
neuropathyDOID:87000.017
neuromuscular diseaseDOID:44000.017
physical disorderDOID:008001500.011
congenital nervous system abnormalityDOID:249000.011