Mus musculus

44 known processes

Fen1

flap structure specific endonuclease 1

(Aliases: AW538437)

Fen1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.705
dna repairGO:00062811070.514
meiotic cell cycleGO:00513211220.377
mitotic cell cycle processGO:19030471590.241
dna recombinationGO:0006310920.227
Yeast
nuclear divisionGO:00002801580.201
gene silencingGO:0016458380.200
dna replicationGO:0006260520.199
organelle fissionGO:00482851700.199
microtubule cytoskeleton organizationGO:00002261570.180
cellular protein catabolic processGO:00442571550.175
regulation of mitotic cell cycle phase transitionGO:1901990730.156
mitotic cell cycleGO:00002781950.150
negative regulation of cell cycleGO:00457861230.141
regulation of cell cycle processGO:00105641600.139
dna dependent dna replicationGO:0006261240.135
Human Yeast
chromatin organizationGO:00063252060.122
negative regulation of mitotic cell cycle phase transitionGO:1901991450.115
double strand break repairGO:0006302480.115
Yeast
regulation of cellular catabolic processGO:00313292420.108
macromolecule catabolic processGO:00090572810.107
meiosis iGO:0007127600.097
regulation of organelle organizationGO:00330432890.097
reciprocal dna recombinationGO:0035825160.094
development of primary sexual characteristicsGO:00451371430.092
Worm
endocytosisGO:00068971680.092
Worm
negative regulation of molecular functionGO:00440922580.090
negative regulation of cell cycle processGO:0010948690.089
regulation of hydrolase activityGO:00513362460.087
meiotic cell cycle processGO:1903046770.084
protein catabolic processGO:00301632210.083
regulation of cell divisionGO:0051302760.081
regulation of mitotic cell cycleGO:00073461260.080
cellular response to dna damage stimulusGO:00069742070.079
amine metabolic processGO:0009308450.077
cell cycle checkpointGO:0000075470.072
regulation of cell cycleGO:00517262810.072
nuclear dna replicationGO:003326030.069
cellular amino acid metabolic processGO:00065201030.067
cellular nitrogen compound catabolic processGO:00442702800.067
mitotic sister chromatid segregationGO:0000070140.067
recombinational repairGO:0000725210.065
regulation of cellular amine metabolic processGO:0033238200.064
response to organic cyclic compoundGO:00140701980.062
cellular amine metabolic processGO:0044106440.061
homeostasis of number of cellsGO:00488722100.061
regulation of chromosome organizationGO:0033044830.060
nucleobase containing small molecule metabolic processGO:00550863520.059
protein ubiquitinationGO:00165671710.059
nitrogen compound transportGO:00717052710.058
oxidation reduction processGO:00551143420.058
body morphogenesisGO:0010171450.058
microtubule based processGO:00070172360.058
regulation of cellular amino acid metabolic processGO:000652150.054
protein processingGO:00164851630.053
negative regulation of cell cycle phase transitionGO:1901988480.052
histone modificationGO:00165701590.050
base excision repairGO:000628490.050
Yeast
cytoplasmic transportGO:00164822340.049
posttranscriptional regulation of gene expressionGO:00106081550.048
negative regulation of cellular component organizationGO:00511291940.048
synapsisGO:0007129340.046
dna modificationGO:0006304500.045
reciprocal meiotic recombinationGO:0007131160.045
double strand break repair via homologous recombinationGO:0000724210.045
protein modification by small protein conjugationGO:00324461870.044
response to inorganic substanceGO:0010035960.043
mrna processingGO:0006397630.043
nuclear transportGO:00511691390.043
proteolysis involved in cellular protein catabolic processGO:00516031470.042
establishment of rna localizationGO:0051236180.042
meiotic nuclear divisionGO:00071261150.042
regulation of nucleoside metabolic processGO:00091181300.041
mitotic recombinationGO:000631230.041
Yeast
gonad developmentGO:00084061410.040
Worm
nucleobase containing compound transportGO:0015931270.040
negative regulation of mitotic cell cycleGO:0045930580.039
regulation of cellular ketone metabolic processGO:0010565660.038
engulfment of apoptotic cellGO:004365230.038
nucleotide metabolic processGO:00091173320.036
protein modification by small protein conjugation or removalGO:00706472070.036
cellular ketone metabolic processGO:0042180840.035
dna geometric changeGO:003239270.035
chromatin modificationGO:00165681870.035
nucleoside triphosphate metabolic processGO:00091412300.035
gland developmentGO:00487323300.035
epithelial tube morphogenesisGO:00605623030.034
spermatogenesisGO:00072832840.034
chromosome organization involved in meiosisGO:0070192390.034
cellular macromolecule catabolic processGO:00442652060.034
forebrain developmentGO:00309003020.034
regulation of cell cycle phase transitionGO:1901987770.034
cell type specific apoptotic processGO:00972852680.033
chromosome segregationGO:0007059480.033
nucleoside phosphate metabolic processGO:00067533380.033
chemotaxisGO:00069352470.033
response to organonitrogen compoundGO:00102432460.033
cell divisionGO:00513011200.032
peptidyl amino acid modificationGO:00181933360.032
cellular homeostasisGO:00197252400.032
organophosphate biosynthetic processGO:00904071220.032
positive regulation of cellular amine metabolic processGO:003324050.031
mitotic nuclear divisionGO:0007067480.031
nucleic acid transportGO:0050657180.031
dna endoreduplicationGO:004202340.031
mrna metabolic processGO:0016071840.031
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.030
mitotic centrosome separationGO:000710040.030
purine ribonucleotide metabolic processGO:00091502900.030
regulation of chromosome segregationGO:0051983210.030
positive regulation of cellular amino acid metabolic processGO:004576430.029
nucleocytoplasmic transportGO:00069131390.029
histone acetylationGO:0016573410.029
germ cell developmentGO:00072811850.029
regulation of histone modificationGO:0031056560.029
glial cell differentiationGO:00100011310.029
leukocyte differentiationGO:00025213420.028
organic cyclic compound catabolic processGO:19013612950.028
negative regulation of phosphate metabolic processGO:00459361840.027
regulation of proteolysisGO:00301621640.027
locomotory behaviorGO:00076261950.027
apoptotic signaling pathwayGO:00971903060.027
purine ribonucleoside triphosphate catabolic processGO:00092071990.026
response to radiationGO:00093141650.026
positive regulation of hydrolase activityGO:00513451480.026
regulation of nucleotide catabolic processGO:00308111220.026
dna unwinding involved in dna replicationGO:000626850.026
ribonucleoside triphosphate catabolic processGO:00092031990.026
mrna transportGO:0051028130.026
leukocyte proliferationGO:00706611720.025
blood circulationGO:00080151950.025
purine containing compound metabolic processGO:00725213110.025
nucleoside phosphate biosynthetic processGO:1901293790.025
dna catabolic processGO:0006308190.025
protein maturationGO:00516041760.024
positive regulation of cell cycleGO:0045787920.024
regulation of purine nucleotide metabolic processGO:19005421690.024
cellular protein complex assemblyGO:00436231160.024
ribose phosphate metabolic processGO:00196932910.024
heterocycle catabolic processGO:00467002800.024
small gtpase mediated signal transductionGO:0007264970.024
regulation of nucleotide metabolic processGO:00061401690.024
intrinsic apoptotic signaling pathwayGO:00971931320.023
intracellular protein transportGO:00068862040.023
negative regulation of atpase activityGO:003278020.023
regulation of kinase activityGO:00435492490.023
cellular response to organonitrogen compoundGO:00714171450.023
chromatin silencingGO:0006342150.023
dna conformation changeGO:0071103370.023
rna transportGO:0050658180.022
anatomical structure homeostasisGO:00602491450.022
digestive system developmentGO:00551232000.022
covalent chromatin modificationGO:00165691630.022
ossificationGO:00015032160.022
translesion synthesisGO:001998510.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
ribonucleoside catabolic processGO:00424542060.022
negative regulation of gene expression epigeneticGO:0045814150.022
mrna 3 end processingGO:0031124160.022
regulation of cellular response to stressGO:00801351590.022
rna dependent dna replicationGO:000627830.021
methylationGO:00322591340.021
myeloid cell differentiationGO:00300992330.021
nucleotide biosynthetic processGO:0009165780.021
regulation of secretionGO:00510462740.021
purine nucleoside triphosphate catabolic processGO:00091462030.021
regulation of secretion by cellGO:19035302490.021
regulation of purine nucleotide catabolic processGO:00331211220.021
regulation of lymphocyte activationGO:00512492400.021
positive regulation of protein modification processGO:00314012990.021
cellular response to hormone stimulusGO:00328701500.020
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
blood vessel morphogenesisGO:00485142850.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
dna duplex unwindingGO:003250870.020
striated muscle myosin thick filament assemblyGO:007168810.020
regulation of protein localizationGO:00328802310.020
negative regulation of atp metabolic processGO:190357940.020
regulation of protein maturationGO:1903317960.020
nucleoside triphosphate catabolic processGO:00091432050.020
negative regulation of proteolysisGO:0045861740.020
negative regulation of protein metabolic processGO:00512482820.019
purine ribonucleoside metabolic processGO:00461282410.019
intra s dna damage checkpointGO:003157340.019
positive regulation of apoptotic processGO:00430652170.019
aromatic compound catabolic processGO:00194392860.019
positive regulation of dna templated transcription elongationGO:003278620.019
rna processingGO:00063961050.019
negative regulation of nucleoside metabolic processGO:0045978110.019
negative regulation of organelle organizationGO:0010639900.019
ribonucleotide catabolic processGO:00092612080.019
nucleoside phosphate catabolic processGO:19012922220.019
purine nucleotide metabolic processGO:00061633020.019
deoxyribonucleotide metabolic processGO:0009262140.019
response to acid chemicalGO:00011011110.018
nucleotide excision repairGO:0006289130.018
regulation of protein kinase activityGO:00458592320.018
embryonic placenta developmentGO:0001892980.018
stem cell differentiationGO:00488632680.018
metaphase plate congressionGO:005131020.018
mitochondrion organizationGO:00070051340.018
regulation of transcription by chromatin organizationGO:003440100.018
heart processGO:0003015940.018
organonitrogen compound catabolic processGO:19015652640.018
gtp catabolic processGO:00061841430.017
cellular response to lipidGO:00713961450.017
mitotic cytokinesisGO:000028140.017
stem cell developmentGO:00488642190.017
negative regulation of cellular amine metabolic processGO:003323910.017
modification dependent protein catabolic processGO:00199411330.017
cellular response to abiotic stimulusGO:0071214560.017
respiratory system developmentGO:00605411900.017
negative regulation of hydrolase activityGO:0051346710.017
cellular chemical homeostasisGO:00550822150.017
camera type eye developmentGO:00430102660.016
Zebrafish
regulation of dna replicationGO:0006275170.016
ribonucleotide metabolic processGO:00092592910.016
meiotic chromosome segregationGO:0045132190.016
placenta developmentGO:00018901400.016
negative regulation of protein processingGO:0010955790.016
muscle cell differentiationGO:00426922610.016
wnt signaling pathwayGO:00160551880.016
interspecies interaction between organismsGO:0044419830.016
negative regulation of protein maturationGO:1903318790.016
sister chromatid segregationGO:0000819200.016
embryonic organ morphogenesisGO:00485622760.016
pyrimidine containing compound metabolic processGO:0072527110.016
multicellular organismal homeostasisGO:00488711640.016
proteasomal protein catabolic processGO:0010498980.016
regulation of protein processingGO:0070613960.016
positive regulation of gtpase activityGO:0043547850.016
cellular response to acid chemicalGO:0071229680.016
circulatory system processGO:00030131970.016
mitotic cell cycle checkpointGO:0007093310.015
glycosyl compound metabolic processGO:19016572460.015
cell cycle g1 s phase transitionGO:0044843570.015
neural tube developmentGO:00219151600.015
phagocytosisGO:0006909660.015
rna splicing via transesterification reactionsGO:0000375430.015
receptor mediated endocytosisGO:0006898510.015
Worm
multi multicellular organism processGO:00447061090.015
establishment of organelle localizationGO:00516561220.015
rho protein signal transductionGO:0007266320.015
cellular response to organic cyclic compoundGO:0071407870.015
purine ribonucleotide catabolic processGO:00091542080.015
pharynx developmentGO:006046510.014
lymphocyte proliferationGO:00466511640.014
negative regulation of cellular protein metabolic processGO:00322692470.014
purine nucleoside catabolic processGO:00061522050.014
response to oxidative stressGO:00069791230.014
membrane organizationGO:00610242450.014
gene silencing by rnaGO:0031047190.014
purine nucleoside metabolic processGO:00422782410.014
regulation of gtp catabolic processGO:00331241130.014
ras protein signal transductionGO:0007265770.014
regulation of hormone levelsGO:00108172110.014
positive regulation of cellular catabolic processGO:00313311480.014
positive regulation of programmed cell deathGO:00430682180.014
myeloid leukocyte differentiationGO:00025731190.014
regulation of apoptotic signaling pathwayGO:20012331970.014
multi organism behaviorGO:0051705620.014
leukocyte activation involved in immune responseGO:00023661260.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.014
digestive tract developmentGO:00485651900.014
regulation of intracellular protein transportGO:0033157820.013
response to steroid hormoneGO:0048545560.013
cofactor metabolic processGO:0051186800.013
mapk cascadeGO:00001652810.013
organophosphate catabolic processGO:00464342320.013
dna dependent dna replication maintenance of fidelityGO:004500530.013
somatic diversification of immune receptorsGO:0002200530.013
amide transportGO:00428861380.013
posttranscriptional gene silencingGO:0016441100.013
hormone secretionGO:00468791280.013
negative regulation of protein modification processGO:00314001630.013
notch signaling pathwayGO:0007219710.013
rna splicingGO:0008380540.013
regulation of cell migrationGO:00303342190.013
nuclear exportGO:0051168340.013
negative regulation of nucleotide catabolic processGO:003081290.013
transcription coupled nucleotide excision repairGO:000628320.013
nucleoside metabolic processGO:00091162460.012
regulation of cell cycle checkpointGO:190197690.012
positive regulation of cell deathGO:00109422240.012
cell adhesionGO:00071553290.012
response to light stimulusGO:00094161350.012
angiogenesisGO:00015252010.012
carbohydrate homeostasisGO:00335001280.012
protein localization to nucleusGO:00345041210.012
positive regulation of histone modificationGO:0031058280.012
regulation of cell activationGO:00508652890.012
b cell activationGO:00421131610.012
protein secretionGO:00093061110.012
female meiotic divisionGO:0007143210.012
regulation of cytoskeleton organizationGO:00514931220.012
purine containing compound catabolic processGO:00725232130.012
rna 3 end processingGO:0031123200.012
cellular protein complex disassemblyGO:0043624360.012
humoral immune responseGO:0006959570.012
protein localization to organelleGO:00333651850.012
dna dealkylationGO:0035510110.012
female gamete generationGO:0007292740.012
carbohydrate derivative catabolic processGO:19011362310.012
regulation of peptidyl lysine acetylationGO:2000756220.012
t cell activationGO:00421102890.012
dna biosynthetic processGO:0071897220.012
Yeast
ribonucleoside metabolic processGO:00091192450.012
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.012
regulation of dna recombinationGO:0000018340.012
sensory perceptionGO:00076002450.012
cation transportGO:00068123990.012
nucleoside catabolic processGO:00091642060.012
negative regulation of immune system processGO:00026832090.012
dendrite developmentGO:00163581150.012
glucose homeostasisGO:00425931280.012
regulation of mitotic sister chromatid segregationGO:0033047120.011
response to oxygen levelsGO:0070482620.011
peptide hormone secretionGO:00300721090.011
nucleus organizationGO:0006997450.011
regulation of protein catabolic processGO:00421761080.011
multicellular organism growthGO:00352641610.011
regulation of endopeptidase activityGO:0052548890.011
regulation of ras gtpase activityGO:0032318880.011
regulation of cellular protein catabolic processGO:1903362610.011
heart morphogenesisGO:00030071780.011
cellular response to cytokine stimulusGO:00713451890.011
positive regulation of gtp catabolic processGO:0033126850.011
positive regulation of secretionGO:00510471300.011
peptide secretionGO:00027901140.011
rna localizationGO:0006403230.011
response to extracellular stimulusGO:00099911270.011
male gamete generationGO:00482322850.011
regulation of bindingGO:00510981110.011
synaptonemal complex assemblyGO:0007130130.011
molting cycleGO:0042303900.011
muscle cell developmentGO:00550011330.011
negative regulation of protein phosphorylationGO:00019331260.011
positive regulation of protein phosphorylationGO:00019342420.011
cardiac muscle tissue developmentGO:00487381300.011
developmental cell growthGO:0048588840.011
telomere maintenanceGO:0000723190.011
negative regulation of cell proliferationGO:00082852960.011
regulation of cell motilityGO:20001452360.011
reactive oxygen species metabolic processGO:0072593840.011
anion transportGO:00068201770.011
response to purine containing compoundGO:0014074280.010
purine ribonucleoside triphosphate metabolic processGO:00092052200.010
striated muscle tissue developmentGO:00147062930.010
positive regulation of purine nucleotide metabolic processGO:19005441140.010
generation of precursor metabolites and energyGO:00060911030.010
telencephalon developmentGO:00215371860.010
immunoglobulin productionGO:0002377730.010
regulation of intracellular transportGO:00323861590.010
peptide transportGO:00158331330.010
response to lipopolysaccharideGO:00324961280.010
negative regulation of intracellular signal transductionGO:19025321670.010

Fen1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012