IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Fibin

fin bud initiation factor homolog (zebrafish)

(Aliases: 1110018M03Rik)

Ensembl: ENSMUSG00000074971
Entrez: 67606
UniProtKB: Q9CQS3

Process Predictions
Disease Predictions

Fibin biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular response to growth factor stimulus	GO:0071363	197	0.094
circulatory system process	GO:0003013	197	0.078
muscle cell differentiation	GO:0042692	261	0.074
renal system development	GO:0072001	225	0.069
angiogenesis	GO:0001525	201	0.066
muscle cell development	GO:0055001	133	0.064
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.061
cellular amino acid metabolic process	GO:0006520	103	0.057
extracellular structure organization	GO:0043062	148	0.057
extracellular matrix organization	GO:0030198	147	0.056
purine ribonucleotide metabolic process	GO:0009150	290	0.055
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.055
regulation of system process	GO:0044057	200	0.053
negative regulation of cell proliferation	GO:0008285	296	0.053
negative regulation of cellular response to growth factor stimulus	GO:0090288	46	0.052
positive regulation of cellular amine metabolic process	GO:0033240	5	0.048
muscle tissue development	GO:0060537	308	0.047
g protein coupled receptor signaling pathway	GO:0007186	243	0.045
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.044
regulation of vasculature development	GO:1901342	88	0.043
striated muscle tissue development	GO:0014706	293	0.042
regulation of cell adhesion	GO:0030155	154	0.040
negative regulation of vasculature development	GO:1901343	26	0.038
response to growth factor	GO:0070848	198	0.038
morphogenesis of embryonic epithelium	GO:0016331	159	0.038
muscle system process	GO:0003012	141	0.038
regulation of body fluid levels	GO:0050878	162	0.038
divalent metal ion transport	GO:0070838	172	0.037
positive regulation of cell adhesion	GO:0045785	80	0.037
connective tissue development	GO:0061448	179	0.037
response to organonitrogen compound	GO:0010243	246	0.036
organonitrogen compound catabolic process	GO:1901565	264	0.036
regulation of muscle system process	GO:0090257	80	0.036
striated muscle cell development	GO:0055002	125	0.036
regulation of cell substrate adhesion	GO:0010810	73	0.035
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.035
cardiac muscle cell differentiation	GO:0055007	69	0.035
response to amino acid	GO:0043200	37	0.034
nucleoside phosphate metabolic process	GO:0006753	338	0.034
heart morphogenesis	GO:0003007	178	0.033
regulation of cellular ketone metabolic process	GO:0010565	66	0.032
oxidation reduction process	GO:0055114	342	0.032
urogenital system development	GO:0001655	261	0.031
negative regulation of blood vessel morphogenesis	GO:2000181	25	0.031
calcium ion transport	GO:0006816	159	0.031
regulation of cellular amine metabolic process	GO:0033238	20	0.031
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.031
skeletal system development	GO:0001501	356	0.030
peptidyl amino acid modification	GO:0018193	336	0.030
actin cytoskeleton organization	GO:0030036	220	0.030
respiratory system development	GO:0060541	190	0.029
developmental growth involved in morphogenesis	GO:0060560	138	0.029
stem cell differentiation	GO:0048863	268	0.029
regulation of angiogenesis	GO:0045765	81	0.028
physiological cardiac muscle hypertrophy	GO:0003301	3	0.028
regulation of cardiac muscle tissue growth	GO:0055021	26	0.028
regulation of cellular component biogenesis	GO:0044087	181	0.027
ribose phosphate metabolic process	GO:0019693	291	0.027
organ growth	GO:0035265	117	0.027
drug metabolic process	GO:0017144	4	0.027
ras protein signal transduction	GO:0007265	77	0.026
nucleotide metabolic process	GO:0009117	332	0.026
respiratory tube development	GO:0030323	167	0.026
mesenchyme development	GO:0060485	152	0.026
regulation of heart growth	GO:0060420	31	0.026
positive regulation of kinase activity	GO:0033674	155	0.025
epithelium migration	GO:0090132	63	0.025
regulation of organelle organization	GO:0033043	289	0.025
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.025
nucleobase containing small molecule metabolic process	GO:0055086	352	0.024
cell growth involved in cardiac muscle cell development	GO:0061049	3	0.024
vascular endothelial growth factor receptor signaling pathway	GO:0048010	24	0.024
cation transport	GO:0006812	399	0.024
cell substrate adhesion	GO:0031589	130	0.023
skeletal muscle organ development	GO:0060538	163	0.023
ribonucleotide metabolic process	GO:0009259	291	0.023
blood vessel morphogenesis	GO:0048514	285	0.023
regulation of cytoskeleton organization	GO:0051493	122	0.023
tissue remodeling	GO:0048771	102	0.023
positive regulation of protein modification process	GO:0031401	299	0.023
single organism cell adhesion	GO:0098602	156	0.023
cytokine production	GO:0001816	319	0.023
cellular ketone metabolic process	GO:0042180	84	0.022
positive regulation of protein phosphorylation	GO:0001934	242	0.022
carbohydrate derivative biosynthetic process	GO:1901137	183	0.022
regulation of homeostatic process	GO:0032844	182	0.022
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	26	0.022
multicellular organismal homeostasis	GO:0048871	164	0.021
sulfur compound metabolic process	GO:0006790	100	0.021
regulation of cellular amino acid metabolic process	GO:0006521	5	0.021
blood circulation	GO:0008015	195	0.021
lung development	GO:0030324	164	0.021
small gtpase mediated signal transduction	GO:0007264	97	0.021
negative regulation of growth	GO:0045926	99	0.021
skeletal system morphogenesis	GO:0048705	203	0.021
hematopoietic progenitor cell differentiation	GO:0002244	143	0.021
mesodermal cell migration	GO:0008078	4	0.020
embryonic epithelial tube formation	GO:0001838	130	0.020
cartilage development	GO:0051216	140	0.020
purine nucleotide metabolic process	GO:0006163	302	0.020
extrinsic apoptotic signaling pathway	GO:0097191	126	0.020
muscle contraction	GO:0006936	101	0.020
digestive system development	GO:0055123	200	0.020
wnt signaling pathway	GO:0016055	188	0.020
endochondral bone morphogenesis	GO:0060350	50	0.020
negative regulation of angiogenesis	GO:0016525	25	0.020
forebrain development	GO:0030900	302	0.019
placenta development	GO:0001890	140	0.019
tissue homeostasis	GO:0001894	115	0.019
positive regulation of erk1 and erk2 cascade	GO:0070374	47	0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.019
hindbrain development	GO:0030902	128	0.019
reactive oxygen species biosynthetic process	GO:1903409	8	0.019
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.019
second messenger mediated signaling	GO:0019932	73	0.019
negative regulation of cellular component organization	GO:0051129	194	0.019
cellular response to acid chemical	GO:0071229	68	0.018
drug catabolic process	GO:0042737	2	0.018
organonitrogen compound biosynthetic process	GO:1901566	192	0.018
camera type eye development	GO:0043010	266	0.018
anatomical structure homeostasis	GO:0060249	145	0.018
kidney development	GO:0001822	213	0.018
regulation of ossification	GO:0030278	112	0.018
compound eye development	GO:0048749	1	0.018
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.018
regulation of cell growth involved in cardiac muscle cell development	GO:0061050	3	0.018
branching morphogenesis of an epithelial tube	GO:0048754	159	0.018
regulation of neuron differentiation	GO:0045664	281	0.017
endochondral bone growth	GO:0003416	19	0.017
regulation of apoptotic signaling pathway	GO:2001233	197	0.017
tissue migration	GO:0090130	68	0.017
cellular amine metabolic process	GO:0044106	44	0.017
physiological muscle hypertrophy	GO:0003298	3	0.017
apoptotic signaling pathway	GO:0097190	306	0.017
inflammatory response	GO:0006954	244	0.017
organelle localization	GO:0051640	179	0.017
negative regulation of intracellular signal transduction	GO:1902532	167	0.017
bone development	GO:0060348	120	0.017
regulation of purine nucleotide metabolic process	GO:1900542	169	0.017
bmp signaling pathway	GO:0030509	93	0.017
cell adhesion	GO:0007155	329	0.017
spinal cord development	GO:0021510	81	0.017
regulation of nucleotide metabolic process	GO:0006140	169	0.017
actomyosin structure organization	GO:0031032	56	0.016
regulation of cell growth	GO:0001558	91	0.016
regulation of tooth mineralization	GO:0070170	2	0.016
regionalization	GO:0003002	337	0.016
muscle fiber development	GO:0048747	76	0.016
transmembrane transport	GO:0055085	412	0.016
positive regulation of cell substrate adhesion	GO:0010811	47	0.016
morphogenesis of a branching epithelium	GO:0061138	193	0.016
positive regulation of camp mediated signaling	GO:0043950	3	0.016
response to acid chemical	GO:0001101	111	0.016
regulation of cytokine production	GO:0001817	266	0.016
cardiac muscle cell development	GO:0055013	39	0.016
carbohydrate metabolic process	GO:0005975	230	0.016
ameboidal type cell migration	GO:0001667	128	0.016
cytokine mediated signaling pathway	GO:0019221	115	0.016
amine metabolic process	GO:0009308	45	0.016
regulation of organ growth	GO:0046620	61	0.016
regulation of mapk cascade	GO:0043408	248	0.016
cellular protein complex assembly	GO:0043623	116	0.016
synaptic transmission	GO:0007268	329	0.016
smoothened signaling pathway	GO:0007224	105	0.016
regulation of removal of superoxide radicals	GO:2000121	4	0.015
neuromuscular process	GO:0050905	99	0.015
morphogenesis of a branching structure	GO:0001763	203	0.015
regulation of muscle tissue development	GO:1901861	97	0.015
biomineral tissue development	GO:0031214	64	0.015
regulation of androgen receptor signaling pathway	GO:0060765	3	0.015
regulation of white fat cell proliferation	GO:0070350	2	0.015
vascular process in circulatory system	GO:0003018	62	0.015
reactive oxygen species metabolic process	GO:0072593	84	0.015
neural tube formation	GO:0001841	108	0.015
epithelial tube formation	GO:0072175	130	0.015
aminoglycan metabolic process	GO:0006022	34	0.015
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.015
peptidyl tyrosine modification	GO:0018212	145	0.015
positive regulation of transcription from rna polymerase i promoter	GO:0045943	3	0.015
heart growth	GO:0060419	45	0.014
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	24	0.014
cyclic nucleotide biosynthetic process	GO:0009190	44	0.014
elastic fiber assembly	GO:0048251	4	0.014
heterocycle catabolic process	GO:0046700	280	0.014
ossification	GO:0001503	216	0.014
cell type specific apoptotic process	GO:0097285	268	0.014
purine containing compound metabolic process	GO:0072521	311	0.014
positive regulation of cell death	GO:0010942	224	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.014
negative regulation of hormone metabolic process	GO:0032351	4	0.014
cellular response to organonitrogen compound	GO:0071417	145	0.014
cell activation involved in immune response	GO:0002263	126	0.014
cellular ion homeostasis	GO:0006873	165	0.014
regulation of cell activation	GO:0050865	289	0.014
regulation of protein binding	GO:0043393	60	0.014
negative regulation of organelle organization	GO:0010639	90	0.014
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.013
reactive nitrogen species metabolic process	GO:2001057	0	0.013
tube closure	GO:0060606	91	0.013
positive regulation of mapk cascade	GO:0043410	170	0.013
regulation of blood pressure	GO:0008217	93	0.013
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.013
asymmetric stem cell division	GO:0098722	3	0.013
smooth muscle contraction	GO:0006939	44	0.013
chondroitin sulfate proteoglycan metabolic process	GO:0050654	20	0.013
purine nucleotide catabolic process	GO:0006195	211	0.013
embryonic organ morphogenesis	GO:0048562	276	0.013
embryonic digit morphogenesis	GO:0042733	56	0.013
muscle adaptation	GO:0043500	39	0.013
multi organism behavior	GO:0051705	62	0.013
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.013
regulation of cardiac muscle tissue development	GO:0055024	31	0.013
rhythmic process	GO:0048511	174	0.013
positive regulation of programmed cell death	GO:0043068	218	0.013
detection of chemical stimulus involved in sensory perception of smell	GO:0050911	4	0.013
protein localization to membrane	GO:0072657	108	0.013
regulation of transferase activity	GO:0051338	263	0.013
stem cell development	GO:0048864	219	0.013
purine ribonucleoside metabolic process	GO:0046128	241	0.013
regulation of odontogenesis	GO:0042481	18	0.012
inner ear morphogenesis	GO:0042472	101	0.012
olfactory lobe development	GO:0021988	32	0.012
glycoprotein metabolic process	GO:0009100	116	0.012
dorsal ventral axon guidance	GO:0033563	3	0.012
response to endoplasmic reticulum stress	GO:0034976	53	0.012
positive regulation of mesenchymal cell proliferation	GO:0002053	33	0.012
establishment or maintenance of cell polarity	GO:0007163	86	0.012
cardiac cell development	GO:0055006	41	0.012
positive regulation of cellular component biogenesis	GO:0044089	94	0.012
regulation of blood circulation	GO:1903522	93	0.012
cellular response to cytokine stimulus	GO:0071345	189	0.012
mesonephros development	GO:0001823	97	0.012
calcium mediated signaling	GO:0019722	46	0.012
cellular nitrogen compound catabolic process	GO:0044270	280	0.012
aromatic compound catabolic process	GO:0019439	286	0.012
primary neural tube formation	GO:0014020	95	0.012
notch signaling pathway	GO:0007219	71	0.012
neural tube development	GO:0021915	160	0.012
regulation of intracellular transport	GO:0032386	159	0.012
cellular homeostasis	GO:0019725	240	0.012
mesenchymal cell differentiation	GO:0048762	107	0.012
immune effector process	GO:0002252	321	0.012
retina development in camera type eye	GO:0060041	119	0.012
ribonucleotide biosynthetic process	GO:0009260	59	0.012
purine nucleoside catabolic process	GO:0006152	205	0.012
mucopolysaccharide metabolic process	GO:1903510	25	0.012
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.012
male anatomical structure morphogenesis	GO:0090598	4	0.012
spermatogenesis	GO:0007283	284	0.012
negative regulation of cell proliferation involved in contact inhibition	GO:0060244	3	0.012
purine nucleoside metabolic process	GO:0042278	241	0.011
production of molecular mediator of immune response	GO:0002440	103	0.011
response to extracellular stimulus	GO:0009991	127	0.011
endomembrane system organization	GO:0010256	147	0.011
regulation of cell projection organization	GO:0031344	206	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.011
olfactory bulb development	GO:0021772	30	0.011
bone morphogenesis	GO:0060349	78	0.011
regulation of binding	GO:0051098	111	0.011
generation of precursor metabolites and energy	GO:0006091	103	0.011
posttranscriptional regulation of gene expression	GO:0010608	155	0.011
embryonic placenta development	GO:0001892	98	0.011
macromolecule catabolic process	GO:0009057	281	0.011
body fluid secretion	GO:0007589	53	0.011
cartilage development involved in endochondral bone morphogenesis	GO:0060351	24	0.011
nucleoside catabolic process	GO:0009164	206	0.011
heart process	GO:0003015	94	0.011
energy derivation by oxidation of organic compounds	GO:0015980	77	0.011
lung alveolus development	GO:0048286	45	0.011
ear morphogenesis	GO:0042471	118	0.011
locomotory behavior	GO:0007626	195	0.011
ribose phosphate biosynthetic process	GO:0046390	59	0.011
positive regulation of transferase activity	GO:0051347	167	0.011
organic cyclic compound catabolic process	GO:1901361	295	0.011
response to oxidative stress	GO:0006979	123	0.011
negative regulation of epithelial cell proliferation	GO:0050680	64	0.011
muscle cell proliferation	GO:0033002	52	0.011
mesenchymal cell proliferation	GO:0010463	44	0.011
hindbrain morphogenesis	GO:0021575	46	0.011
positive regulation of nucleotide metabolic process	GO:0045981	114	0.011
nucleoside phosphate catabolic process	GO:1901292	222	0.011
epithelial tube morphogenesis	GO:0060562	303	0.011
digestive tract morphogenesis	GO:0048546	147	0.011
cardiac muscle tissue development	GO:0048738	130	0.011
organophosphate catabolic process	GO:0046434	232	0.011
regulation of vesicle mediated transport	GO:0060627	139	0.011
neuron migration	GO:0001764	122	0.011
regulation of erk1 and erk2 cascade	GO:0070372	71	0.011
ion transmembrane transport	GO:0034220	361	0.011
naphthalene containing compound metabolic process	GO:0090420	1	0.011
regulation of anatomical structure size	GO:0090066	178	0.011
purine ribonucleoside catabolic process	GO:0046130	205	0.011
positive regulation of protein kinase activity	GO:0045860	144	0.011
regulation of stem cell proliferation	GO:0072091	78	0.011
regulation of secretion by cell	GO:1903530	249	0.011
endocrine system development	GO:0035270	98	0.011
submandibular salivary gland formation	GO:0060661	1	0.011
positive regulation of neuron differentiation	GO:0045666	141	0.011
development of primary sexual characteristics	GO:0045137	143	0.011
ear development	GO:0043583	200	0.011
cell growth	GO:0016049	130	0.011
organophosphate biosynthetic process	GO:0090407	122	0.011
cardiocyte differentiation	GO:0035051	87	0.011
regulation of macrophage migration inhibitory factor signaling pathway	GO:2000446	1	0.011
regulation of ras protein signal transduction	GO:0046578	114	0.011
cellular glucan metabolic process	GO:0006073	32	0.010
protein maturation	GO:0051604	176	0.010
lymphocyte activation involved in immune response	GO:0002285	93	0.010
epithelial cell proliferation	GO:0050673	174	0.010
spermatid development	GO:0007286	108	0.010
mesoderm development	GO:0007498	100	0.010
t cell activation involved in immune response	GO:0002286	43	0.010
intrinsic apoptotic signaling pathway	GO:0097193	132	0.010
microtubule cytoskeleton organization	GO:0000226	157	0.010
actin mediated cell contraction	GO:0070252	15	0.010
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.010
cation transmembrane transport	GO:0098655	266	0.010

Fibin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.043
musculoskeletal system disease	DOID:17	0.043
myopathy	DOID:423	0.043
muscle tissue disease	DOID:66	0.043
muscular disease	DOID:0080000	0.043
muscular dystrophy	DOID:9884	0.019
limb girdle muscular dystrophy	DOID:11724	0.019
cardiovascular system disease	DOID:1287	0.013
heart disease	DOID:114	0.013
nervous system disease	DOID:863	0.012
anemia	DOID:2355	0.010
immune system disease	DOID:2914	0.010
hematopoietic system disease	DOID:74	0.010

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