Mus musculus

79 known processes

Pcna

proliferating cell nuclear antigen

Pcna biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.988
recombinational repairGO:0000725210.952
regulation of mitotic cell cycleGO:00073461260.889
dna metabolic processGO:00062593030.881
meiotic cell cycleGO:00513211220.871
dna packagingGO:0006323300.870
mrna metabolic processGO:0016071840.767
dna repairGO:00062811070.713
double strand break repairGO:0006302480.673
meiotic nuclear divisionGO:00071261150.668
dna conformation changeGO:0071103370.660
g1 s transition of mitotic cell cycleGO:0000082570.649
regulation of cell cycle processGO:00105641600.536
modification dependent macromolecule catabolic processGO:00436321330.527
cellular protein catabolic processGO:00442571550.518
ubiquitin dependent protein catabolic processGO:00065111290.484
regulation of cell cycle phase transitionGO:1901987770.482
modification dependent protein catabolic processGO:00199411330.476
heterocycle catabolic processGO:00467002800.461
Human
regulation of glycogen catabolic processGO:000598120.442
regulation of cell cycleGO:00517262810.411
gonad developmentGO:00084061410.410
inseminationGO:000732060.400
copulationGO:000762070.390
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.386
mrna processingGO:0006397630.357
microtubule based processGO:00070172360.355
Fly
regulation of cellular response to stressGO:00801351590.338
germ cell developmentGO:00072811850.335
positive regulation of cell cycleGO:0045787920.322
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.315
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.313
double strand break repair via homologous recombinationGO:0000724210.306
meiosis iGO:0007127600.293
mitotic cell cycle processGO:19030471590.283
Fly
mitotic centrosome separationGO:000710040.282
negative regulation of meiotic cell cycleGO:0051447140.279
proteolysis involved in cellular protein catabolic processGO:00516031470.277
small gtpase mediated signal transductionGO:0007264970.277
synapsisGO:0007129340.276
dna replicationGO:0006260520.266
Fly
nucleic acid transportGO:0050657180.258
mrna splicing via spliceosomeGO:0000398430.258
development of primary sexual characteristicsGO:00451371430.245
carbohydrate metabolic processGO:00059752300.238
protein ubiquitinationGO:00165671710.238
posttranscriptional gene silencing by rnaGO:0035194100.237
organelle fissionGO:00482851700.235
mitotic cell cycleGO:00002781950.225
Fly
cell cycle checkpointGO:0000075470.222
regulation of mitotic cell cycle phase transitionGO:1901990730.215
ras protein signal transductionGO:0007265770.209
regulation of response to dna damage stimulusGO:2001020340.205
microtubule cytoskeleton organizationGO:00002261570.201
Fly
mitotic nuclear divisionGO:0007067480.197
cellular macromolecule catabolic processGO:00442652060.189
Human
dna dependent dna replicationGO:0006261240.182
rna processingGO:00063961050.180
response to metal ionGO:0010038470.179
gene silencingGO:0016458380.179
cellular glucan metabolic processGO:0006073320.177
meiotic chromosome segregationGO:0045132190.177
deoxyribonucleotide biosynthetic processGO:000926360.175
centrosome separationGO:005129940.173
aromatic compound catabolic processGO:00194392860.172
Human
regulation of nuclear divisionGO:0051783560.172
cellular carbohydrate metabolic processGO:00442621190.169
spermatogenesisGO:00072832840.156
male gamete generationGO:00482322850.154
rna splicingGO:0008380540.151
mitotic sister chromatid separationGO:005130690.148
meiotic cell cycle processGO:1903046770.140
cell cycle g1 s phase transitionGO:0044843570.136
regulation of cellular catabolic processGO:00313292420.136
Human
regulation of organelle organizationGO:00330432890.129
response to uvGO:0009411440.128
response to light stimulusGO:00094161350.127
negative regulation of chromosome organizationGO:2001251300.127
oxidation reduction processGO:00551143420.127
cellular lipid metabolic processGO:00442553230.119
negative regulation of cellular protein metabolic processGO:00322692470.118
genitalia developmentGO:0048806370.111
cellular response to lipidGO:00713961450.109
response to inorganic substanceGO:0010035960.107
regulation of protein complex disassemblyGO:0043244280.104
regulation of cellular protein catabolic processGO:1903362610.103
female gamete generationGO:0007292740.103
cellular amino acid metabolic processGO:00065201030.102
rna interferenceGO:001624620.101
posttranscriptional gene silencingGO:0016441100.101
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.100
protein modification by small protein conjugation or removalGO:00706472070.099
translationGO:0006412930.097
positive regulation of cell cycle processGO:0090068610.093
protein modification by small protein conjugationGO:00324461870.092
cellular nitrogen compound catabolic processGO:00442702800.090
Human
negative regulation of cellular component organizationGO:00511291940.090
nucleobase containing small molecule metabolic processGO:00550863520.090
cellular polysaccharide metabolic processGO:0044264380.089
gene silencing by rnaGO:0031047190.088
regulation of intracellular transportGO:00323861590.088
glycogen metabolic processGO:0005977320.087
negative regulation of cell cycle processGO:0010948690.086
cell divisionGO:00513011200.086
apoptotic signaling pathwayGO:00971903060.083
synaptonemal complex assemblyGO:0007130130.083
regulation of mrna processingGO:0050684410.082
chromatin organizationGO:00063252060.081
mrna catabolic processGO:0006402220.080
regulation of mrna splicing via spliceosomeGO:0048024320.079
positive regulation of mitotic cell cycleGO:0045931410.079
response to oxidative stressGO:00069791230.079
negative regulation of mitotic cell cycle phase transitionGO:1901991450.079
regulation of ras protein signal transductionGO:00465781140.078
chromosome segregationGO:0007059480.078
polysaccharide metabolic processGO:0005976390.078
synaptonemal complex organizationGO:0070193150.076
negative regulation of cell cycleGO:00457861230.075
body morphogenesisGO:0010171450.074
macromolecule catabolic processGO:00090572810.073
Human
energy derivation by oxidation of organic compoundsGO:0015980770.073
regulation of rna splicingGO:0043484370.071
cellular chemical homeostasisGO:00550822150.071
regulation of proteasomal protein catabolic processGO:0061136460.069
regulation of carbohydrate metabolic processGO:0006109750.068
response to organic cyclic compoundGO:00140701980.067
nuclear transportGO:00511691390.067
regulation of proteolysisGO:00301621640.067
monosaccharide metabolic processGO:00059961060.067
spindle assembly involved in female meiosis iGO:000705720.067
proteasomal protein catabolic processGO:0010498980.067
double strand break repair via nonhomologous end joiningGO:0006303100.065
mitotic g1 dna damage checkpointGO:003157140.064
dna templated transcription terminationGO:000635340.064
oogenesisGO:0048477560.063
non recombinational repairGO:0000726100.062
cellular response to organic cyclic compoundGO:0071407870.062
protein complex disassemblyGO:0043241400.061
rna splicing via transesterification reactionsGO:0000375430.060
cellular polysaccharide catabolic processGO:004424750.060
intra s dna damage checkpointGO:003157340.059
regulation of lipid metabolic processGO:00192161180.059
endocytosisGO:00068971680.059
energy reserve metabolic processGO:0006112390.059
chromatin modificationGO:00165681870.059
organ regenerationGO:003110020.058
ossificationGO:00015032160.057
peptidyl amino acid modificationGO:00181933360.056
receptor mediated endocytosisGO:0006898510.056
response to steroid hormoneGO:0048545560.055
protein maturationGO:00516041760.055
regulation of protein maturationGO:1903317960.055
cellular response to hormone stimulusGO:00328701500.054
lung developmentGO:00303241640.053
protein catabolic processGO:00301632210.053
regulation of cellular carbohydrate metabolic processGO:0010675750.052
axon guidanceGO:00074111410.052
regulation of mitosisGO:0007088290.052
dna recombinationGO:0006310920.052
positive regulation of protein modification processGO:00314012990.051
generation of precursor metabolites and energyGO:00060911030.051
mapk cascadeGO:00001652810.051
regenerationGO:0031099380.051
negative regulation of organelle organizationGO:0010639900.050
nucleotide metabolic processGO:00091173320.050
regulation of hydrolase activityGO:00513362460.050
Human
base excision repairGO:000628490.049
dna integrity checkpointGO:0031570280.048
positive regulation of organelle organizationGO:00106381280.047
dna replication independent nucleosome assemblyGO:000633610.047
protein localization to organelleGO:00333651850.046
regulation of cell divisionGO:0051302760.046
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.046
glucan metabolic processGO:0044042320.045
regulation of double strand break repair via nonhomologous end joiningGO:200103220.044
histone acetylationGO:0016573410.044
positive regulation of protein phosphorylationGO:00019342420.044
regulation of microtubule based processGO:0032886520.043
regulation of cell cycle checkpointGO:190197690.043
oocyte anterior posterior axis specificationGO:000731420.043
regulation of protein processingGO:0070613960.042
respiratory system developmentGO:00605411900.042
nuclear divisionGO:00002801580.042
nucleobase containing compound transportGO:0015931270.041
regulation of chromosome organizationGO:0033044830.041
mitotic cell cycle embryonicGO:004544850.041
chromatin assemblyGO:0031497130.041
glucose metabolic processGO:0006006920.040
spermatid developmentGO:00072861080.040
respiratory tube developmentGO:00303231670.040
locomotory behaviorGO:00076261950.039
regulation of erk1 and erk2 cascadeGO:0070372710.039
protein processingGO:00164851630.039
intracellular protein transportGO:00068862040.039
posttranscriptional regulation of gene expressionGO:00106081550.039
regulation of lymphocyte activationGO:00512492400.038
dna replication checkpointGO:000007620.038
mitotic cell cycle checkpointGO:0007093310.038
oocyte maturationGO:0001556180.037
regulation of chromosome segregationGO:0051983210.037
regulation of cell cycle g1 s phase transitionGO:1902806350.037
regulation of protein catabolic processGO:00421761080.037
fertilizationGO:00095661270.037
homeostasis of number of cellsGO:00488722100.036
covalent chromatin modificationGO:00165691630.036
dna catabolic process exonucleolyticGO:000073830.036
amine metabolic processGO:0009308450.036
chromosome condensationGO:0030261100.036
organophosphate biosynthetic processGO:00904071220.034
adult locomotory behaviorGO:0008344910.034
negative regulation of protein metabolic processGO:00512482820.033
oocyte constructionGO:000730820.033
organic cyclic compound catabolic processGO:19013612950.033
Human
regulation of transferase activityGO:00513382630.033
cell growthGO:00160491300.032
skin developmentGO:00435882200.032
rna localizationGO:0006403230.032
regulation of carbohydrate catabolic processGO:0043470120.031
regulation of dna recombinationGO:0000018340.031
glucan catabolic processGO:000925150.031
negative regulation of b cell differentiationGO:004557840.031
regulation of nucleoside metabolic processGO:00091181300.031
organelle localizationGO:00516401790.031
positive regulation of cell divisionGO:0051781310.030
protein localization to chromosome centromeric regionGO:007145910.030
negative regulation of proteolysisGO:0045861740.030
positive regulation of nuclear divisionGO:0051785270.030
negative regulation of molecular functionGO:00440922580.029
dendrite developmentGO:00163581150.029
glycogen catabolic processGO:000598050.028
nitrogen compound transportGO:00717052710.028
ribonucleoside catabolic processGO:00424542060.028
pharynx developmentGO:006046510.028
positive regulation of cellular amine metabolic processGO:003324050.028
regulation of nucleocytoplasmic transportGO:0046822730.028
positive regulation of cytoskeleton organizationGO:0051495490.028
circadian regulation of gene expressionGO:0032922480.028
positive regulation of glycogen catabolic processGO:004581920.028
positive regulation of apoptotic processGO:00430652170.027
sister chromatid segregationGO:0000819200.027
response to alcoholGO:0097305480.027
negative regulation of mitotic cell cycleGO:0045930580.026
cytoplasmic transportGO:00164822340.026
regulation of mapk cascadeGO:00434082480.026
positive regulation of dna replicationGO:004574090.026
positive regulation of protein kinase activityGO:00458601440.026
negative regulation of protein maturationGO:1903318790.026
histone modificationGO:00165701590.026
organelle assemblyGO:00709251770.026
dna dependent dna replication maintenance of fidelityGO:004500530.026
dna damage response signal transduction by p53 class mediatorGO:0030330190.026
cellular ketone metabolic processGO:0042180840.025
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.025
response to radiationGO:00093141650.025
nucleoside monophosphate catabolic processGO:0009125590.024
nucleocytoplasmic transportGO:00069131390.024
positive regulation of mapk cascadeGO:00434101700.024
negative regulation of cell cycle phase transitionGO:1901988480.024
regulation of exit from mitosisGO:000709610.024
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.024
negative regulation of cellular protein catabolic processGO:1903363220.024
negative regulation of gene expression epigeneticGO:0045814150.024
mitotic spindle organizationGO:0007052100.024
Fly
regulation of cellular ketone metabolic processGO:0010565660.023
hexose metabolic processGO:0019318980.023
protein localization to nucleusGO:00345041210.023
regulation of protein kinase activityGO:00458592320.023
multicellular organismal reproductive behaviorGO:0033057230.023
regulation of glucose metabolic processGO:0010906600.023
chemotaxisGO:00069352470.023
organ growthGO:00352651170.023
cellular homeostasisGO:00197252400.023
negative regulation of protein processingGO:0010955790.022
regulation of polyamine transmembrane transportGO:190226750.022
protein dna complex subunit organizationGO:0071824280.022
nucleic acid phosphodiester bond hydrolysisGO:0090305490.022
Human
microtubule cytoskeleton organization involved in mitosisGO:190285040.022
b cell activationGO:00421131610.022
positive regulation of transferase activityGO:00513471670.022
regulation of cellular component biogenesisGO:00440871810.022
regulation of purine nucleotide catabolic processGO:00331211220.022
mitotic g2 dna damage checkpointGO:000709580.021
response to drugGO:0042493750.021
negative regulation of protein catabolic processGO:0042177360.021
cellular response to metal ionGO:0071248310.021
regulation of g1 s transition of mitotic cell cycleGO:2000045350.021
regulation of apoptotic signaling pathwayGO:20012331970.021
positive regulation of cell deathGO:00109422240.021
regulation of meiosis iGO:006063170.021
positive regulation of mrna processingGO:0050685160.021
positive regulation of triglyceride catabolic processGO:001089830.021
positive regulation of protein serine threonine kinase activityGO:00719021060.020
positive regulation of mrna metabolic processGO:1903313170.020
axonogenesisGO:00074092740.020
nucleoside catabolic processGO:00091642060.020
b cell differentiationGO:0030183780.020
negative regulation of nuclear divisionGO:0051784190.020
regulation of meiotic cell cycleGO:0051445340.020
blastocyst developmentGO:0001824800.020
positive regulation of lipid metabolic processGO:0045834400.019
oocyte developmentGO:0048599330.019
regulation of cell growthGO:0001558910.019
cellular carbohydrate catabolic processGO:0044275150.019
regulation of circadian rhythmGO:0042752580.019
positive regulation of cell cycle phase transitionGO:1901989170.019
spindle assembly involved in mitosisGO:009030740.019
positive regulation of programmed cell deathGO:00430682180.019
positive regulation of hydrolase activityGO:00513451480.018
Human
negative regulation of cellular catabolic processGO:0031330470.018
negative regulation of phagocytosisGO:005076540.018
rna dependent dna replicationGO:000627830.018
response to oxygen levelsGO:0070482620.018
regulation of cytoplasmic transportGO:19036491120.018
dephosphorylationGO:00163111290.018
nucleosome assemblyGO:000633470.018
cell cycle comprising mitosis without cytokinesisGO:003330110.017
establishment of organelle localizationGO:00516561220.017
jak stat cascadeGO:0007259420.017
carbohydrate derivative biosynthetic processGO:19011371830.017
cardiac muscle tissue developmentGO:00487381300.017
cardiac muscle cell differentiationGO:0055007690.017
adult behaviorGO:00305341350.017
regulation of multi organism processGO:00439001110.017
forebrain developmentGO:00309003020.016
regulation of mrna metabolic processGO:1903311430.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
positive regulation of erk1 and erk2 cascadeGO:0070374470.016
phagocytosisGO:0006909660.016
response to estrogenGO:0043627240.016
cellular response to organonitrogen compoundGO:00714171450.016
regulation of purine nucleotide metabolic processGO:19005421690.016
deoxyribonucleotide metabolic processGO:0009262140.016
segmentationGO:0035282930.016
lymphocyte proliferationGO:00466511640.016
cation transportGO:00068123990.015
microtubule organizing center organizationGO:0031023280.015
ribonucleotide catabolic processGO:00092612080.015
positive regulation of nucleotide metabolic processGO:00459811140.015
positive regulation of striated muscle tissue developmentGO:0045844310.015
neural tube closureGO:0001843900.015
nuclear dna replicationGO:003326030.015
erk1 and erk2 cascadeGO:0070371770.015
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114590.015
viral life cycleGO:0019058360.015
internal protein amino acid acetylationGO:0006475420.015
regulation of cellular amino acid metabolic processGO:000652150.015
response to growth factorGO:00708481980.015
positive regulation of meiotic cell cycleGO:0051446150.015
regulation of organ growthGO:0046620610.015
cell cycle g2 m phase transitionGO:0044839200.014
muscle cell proliferationGO:0033002520.014
regulation of body fluid levelsGO:00508781620.014
positive regulation of cellular catabolic processGO:00313311480.014
Human
gene silencing by mirnaGO:0035195100.014
anatomical structure homeostasisGO:00602491450.014
single fertilizationGO:0007338820.014
positive regulation of phosphatase activityGO:001092240.014
body fluid secretionGO:0007589530.014
purine nucleotide catabolic processGO:00061952110.014
negative regulation of growthGO:0045926990.014
chromatin remodelingGO:0006338320.014
negative regulation of intracellular signal transductionGO:19025321670.013
negative regulation of myeloid cell differentiationGO:0045638380.013
regulation of homeostatic processGO:00328441820.013
regulation of cellular carbohydrate catabolic processGO:0043471120.013
positive regulation of cell developmentGO:00107202370.013
regulation of cellular amine metabolic processGO:0033238200.013
meiotic chromosome condensationGO:001003230.013
cardiac cell developmentGO:0055006410.013
intracellular mrna localizationGO:000829840.013
positive regulation of secretion by cellGO:19035321140.013
rhythmic processGO:00485111740.013
establishment or maintenance of cell polarityGO:0007163860.013
rna transportGO:0050658180.013
dna damage checkpointGO:0000077260.013
purine ribonucleoside metabolic processGO:00461282410.012
striated muscle tissue developmentGO:00147062930.012
organophosphate catabolic processGO:00464342320.012
nucleoside phosphate biosynthetic processGO:1901293790.012
lipid biosynthetic processGO:00086101790.012
female sex determinationGO:003023710.012
regionalizationGO:00030023370.012
response to iron ionGO:001003940.012
response to transition metal nanoparticleGO:1990267110.012
nucleosome positioningGO:001658440.012
purine containing compound catabolic processGO:00725232130.012
response to hydrogen peroxideGO:0042542320.012
nuclear transcribed mrna catabolic processGO:0000956160.012
leukocyte proliferationGO:00706611720.012
positive regulation of kinase activityGO:00336741550.012
regulation of embryonic developmentGO:0045995710.012
negative regulation of phosphorylationGO:00423261660.012
positive regulation of rna splicingGO:0033120120.012
camera type eye developmentGO:00430102660.012
regulation of microtubule cytoskeleton organizationGO:0070507370.012
ribonucleotide metabolic processGO:00092592910.012
sensory perceptionGO:00076002450.011
cell type specific apoptotic processGO:00972852680.011
regulation of glycogen metabolic processGO:0070873130.011
regulation of double strand break repair via homologous recombinationGO:001056920.011
negative regulation of apoptotic cell clearanceGO:200042610.011
protein depolymerizationGO:0051261340.011
regulation of cell cycle g2 m phase transitionGO:1902749100.011
ribosomal small subunit biogenesisGO:004227440.011
negative regulation of g1 s transition of mitotic cell cycleGO:2000134180.011
protein homooligomerizationGO:0051260430.011
telencephalon developmentGO:00215371860.011
dna biosynthetic processGO:0071897220.011
Human
negative regulation of multi organism processGO:0043901680.011
carbohydrate homeostasisGO:00335001280.011
cardiac muscle tissue growthGO:0055017370.011
regulation of translationGO:0006417710.011
peptidyl lysine acetylationGO:0018394450.011
regulation of hormone levelsGO:00108172110.011
viral processGO:0016032410.011
regulation of secretion by cellGO:19035302490.011
regulation of lymphocyte differentiationGO:00456191070.011
negative regulation of leukocyte differentiationGO:1902106510.011
regulation of peptidase activityGO:0052547960.011
ribonucleoprotein complex localizationGO:007116610.011
nucleoside phosphate metabolic processGO:00067533380.011
oocyte differentiationGO:0009994350.011
macromolecular complex disassemblyGO:0032984430.011
neuron migrationGO:00017641220.011
regulation of b cell differentiationGO:0045577230.010
protein import into nucleusGO:0006606950.010
positive regulation of growthGO:00459271040.010
molting cycleGO:0042303900.010
male gonad developmentGO:0008584880.010
synapse organizationGO:00508081250.010

Pcna disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012