| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.223 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.211 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.165 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.165 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.159 | |
| endoplasmic reticulum tubular network organization | GO:0071786 | 1 | 0.135 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.117 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.115 | |
| protein ubiquitination | GO:0016567 | 171 | 0.077 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.072 | |
| dna recombination | GO:0006310 | 92 | 0.066 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.063 | |
| protein catabolic process | GO:0030163 | 221 | 0.055 | |
| double strand break repair via homologous recombination | GO:0000724 | 21 | 0.055 | |
| gpi anchor metabolic process | GO:0006505 | 7 | 0.055 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.051 | |
| translesion synthesis | GO:0019985 | 1 | 0.050 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.047 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.047 | |
| mitochondrion degradation | GO:0000422 | 3 | 0.045 | |
| chiasma assembly | GO:0051026 | 6 | 0.042 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 25 | 0.042 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.042 | |
| spermatogenesis | GO:0007283 | 284 | 0.040 | |
| calcium ion transmembrane transport | GO:0070588 | 85 | 0.037 | |
| recombinational repair | GO:0000725 | 21 | 0.036 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.036 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.035 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.034 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.034 | |
| stem cell differentiation | GO:0048863 | 268 | 0.033 | |
| meiosis i | GO:0007127 | 60 | 0.033 | |
| dna metabolic process | GO:0006259 | 303 | 0.032 | |
| germ cell development | GO:0007281 | 185 | 0.032 | |
| synapsis | GO:0007129 | 34 | 0.031 | |
| vacuole organization | GO:0007033 | 38 | 0.031 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.031 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.031 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.031 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.030 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.030 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.030 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.029 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.029 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.029 | |
| double strand break repair | GO:0006302 | 48 | 0.029 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.028 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.028 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.027 | |
| protein lipidation | GO:0006497 | 28 | 0.027 | |
| regulation of protein localization | GO:0032880 | 231 | 0.026 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.026 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.026 | |
| endomembrane system organization | GO:0010256 | 147 | 0.026 | |
| spermatid development | GO:0007286 | 108 | 0.026 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.025 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.025 | |
| regulation of protein stability | GO:0031647 | 52 | 0.025 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.025 | |
| lipoprotein metabolic process | GO:0042157 | 43 | 0.024 | |
| heart process | GO:0003015 | 94 | 0.024 | |
| regulation of system process | GO:0044057 | 200 | 0.023 | |
| dna repair | GO:0006281 | 107 | 0.023 | |
| calcium ion transport | GO:0006816 | 159 | 0.023 | |
| heart contraction | GO:0060047 | 93 | 0.022 | |
| organelle fission | GO:0048285 | 170 | 0.022 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.022 | |
| cellular homeostasis | GO:0019725 | 240 | 0.021 | |
| male gamete generation | GO:0048232 | 285 | 0.021 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.021 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.021 | |
| axoneme assembly | GO:0035082 | 15 | 0.021 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.021 | |
| nuclear division | GO:0000280 | 158 | 0.021 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.021 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.021 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.020 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.020 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.020 | |
| protein localization to organelle | GO:0033365 | 185 | 0.020 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.020 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.019 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.019 | |
| regulation of blood circulation | GO:1903522 | 93 | 0.019 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.019 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.019 | |
| transmembrane transport | GO:0055085 | 412 | 0.018 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.018 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.018 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.018 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.018 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.018 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.018 | |
| dipeptide transport | GO:0042938 | 2 | 0.018 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.018 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.017 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.017 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 31 | 0.017 | |
| immune effector process | GO:0002252 | 321 | 0.017 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.017 | |
| microtubule based process | GO:0007017 | 236 | 0.017 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.017 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.017 | |
| synaptonemal complex organization | GO:0070193 | 15 | 0.017 | |
| response to light stimulus | GO:0009416 | 135 | 0.016 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.016 | |
| scf dependent proteasomal ubiquitin dependent protein catabolic process | GO:0031146 | 10 | 0.016 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.016 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.016 | |
| blastocyst development | GO:0001824 | 80 | 0.016 | |
| skeletal system development | GO:0001501 | 356 | 0.016 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.015 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.015 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.015 | |
| regulation of protein transport | GO:0051223 | 163 | 0.015 | |
| regulation of secretion | GO:0051046 | 274 | 0.015 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.015 | |
| amine metabolic process | GO:0009308 | 45 | 0.015 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.015 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.015 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.015 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.015 | |
| negative regulation of camp mediated signaling | GO:0043951 | 3 | 0.015 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.015 | |
| synaptic transmission | GO:0007268 | 329 | 0.015 | |
| cation transport | GO:0006812 | 399 | 0.015 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.015 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.014 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.014 | |
| organelle assembly | GO:0070925 | 177 | 0.014 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.014 | |
| negative regulation of chromosome organization | GO:2001251 | 30 | 0.014 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.014 | |
| mitotic g1 dna damage checkpoint | GO:0031571 | 4 | 0.014 | |
| response to radiation | GO:0009314 | 165 | 0.014 | |
| centrosome separation | GO:0051299 | 4 | 0.014 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.014 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.014 | |
| protein secretion | GO:0009306 | 111 | 0.014 | |
| peptide transport | GO:0015833 | 133 | 0.014 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.014 | |
| reciprocal dna recombination | GO:0035825 | 16 | 0.014 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.014 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.014 | |
| membrane organization | GO:0061024 | 245 | 0.014 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.014 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.014 | |
| gonad development | GO:0008406 | 141 | 0.013 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.013 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.013 | |
| leukocyte migration | GO:0050900 | 124 | 0.013 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.013 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.013 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.013 | |
| intracellular protein transport | GO:0006886 | 204 | 0.013 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 40 | 0.013 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.013 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.013 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.013 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.013 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.013 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.012 | |
| regulation of heart contraction | GO:0008016 | 77 | 0.012 | |
| protein processing | GO:0016485 | 163 | 0.012 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 10 | 0.012 | |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.012 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.012 | |
| histone modification | GO:0016570 | 159 | 0.012 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.012 | |
| regulation of meiosis i | GO:0060631 | 7 | 0.012 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.012 | |
| circulatory system process | GO:0003013 | 197 | 0.012 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.012 | |
| amide transport | GO:0042886 | 138 | 0.012 | |
| respiratory system development | GO:0060541 | 190 | 0.012 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.012 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.012 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 23 | 0.011 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.011 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.011 | |
| asymmetric stem cell division | GO:0098722 | 3 | 0.011 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.011 | |
| blood circulation | GO:0008015 | 195 | 0.011 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.011 | |
| tube formation | GO:0035148 | 140 | 0.011 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.011 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.011 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.011 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.011 | |
| protein maturation | GO:0051604 | 176 | 0.011 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.011 | |
| regulation of cell migration | GO:0030334 | 219 | 0.011 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.011 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.011 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.011 | |
| protein neddylation | GO:0045116 | 1 | 0.011 | |
| respiratory tube development | GO:0030323 | 167 | 0.011 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.011 | |
| regulation of long term synaptic potentiation | GO:1900271 | 4 | 0.011 | |
| regulation of muscle system process | GO:0090257 | 80 | 0.010 | |
| organelle localization | GO:0051640 | 179 | 0.010 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.010 | |
| cell adhesion | GO:0007155 | 329 | 0.010 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.010 | |
| neural tube formation | GO:0001841 | 108 | 0.010 | |
| gtp metabolic process | GO:0046039 | 144 | 0.010 | |
| regulation of glycogen catabolic process | GO:0005981 | 2 | 0.010 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 46 | 0.010 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.010 | |
| cellularization | GO:0007349 | 1 | 0.010 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.010 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.010 | |
| regulation of cardiac muscle contraction | GO:0055117 | 21 | 0.010 | |
| muscle contraction | GO:0006936 | 101 | 0.010 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.010 | |
| microtubule organizing center organization | GO:0031023 | 28 | 0.010 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.010 | |
| protein demethylation | GO:0006482 | 13 | 0.010 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.010 | |
| l amino acid transport | GO:0015807 | 32 | 0.010 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.010 | |
