Mus musculus

27 known processes

Pgk1

phosphoglycerate kinase 1

(Aliases: MGC118097,Pgk-1)

Pgk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hexose catabolic processGO:001932030.999
nadph regenerationGO:000674020.995
glycolytic processGO:0006096200.991
pyruvate metabolic processGO:0006090280.936
pentose phosphate shuntGO:000609820.930
sperm motilityGO:0030317470.908
glucose catabolic processGO:000600730.875
ribonucleoside monophosphate biosynthetic processGO:000915690.849
oxidation reduction processGO:00551143420.837
monocarboxylic acid metabolic processGO:00327871910.746
generation of precursor metabolites and energyGO:00060911030.720
nucleoside monophosphate metabolic processGO:0009123850.708
atp metabolic processGO:0046034750.663
monosaccharide metabolic processGO:00059961060.659
Rat
nucleobase containing small molecule metabolic processGO:00550863520.644
hexose metabolic processGO:0019318980.620
Rat
carbohydrate catabolic processGO:0016052320.575
substantia nigra developmentGO:002176220.526
nadp metabolic processGO:000673960.495
purine containing compound metabolic processGO:00725213110.482
cellular aldehyde metabolic processGO:0006081120.456
ribose phosphate biosynthetic processGO:0046390590.443
nucleotide metabolic processGO:00091173320.434
nucleoside metabolic processGO:00091162460.406
nucleoside triphosphate metabolic processGO:00091412300.386
nucleoside phosphate metabolic processGO:00067533380.374
nucleoside biosynthetic processGO:0009163210.367
carbohydrate metabolic processGO:00059752300.352
striated muscle myosin thick filament assemblyGO:007168810.352
myosin filament organizationGO:003103330.343
purine nucleotide metabolic processGO:00061633020.338
purine nucleoside biosynthetic processGO:0042451190.286
lactate biosynthetic processGO:001924940.271
regulation of coenzyme metabolic processGO:005119640.243
purine ribonucleoside metabolic processGO:00461282410.241
purine nucleoside monophosphate biosynthetic processGO:000912790.236
coenzyme metabolic processGO:0006732520.236
energy derivation by oxidation of organic compoundsGO:0015980770.230
response to decreased oxygen levelsGO:0036293590.230
cofactor metabolic processGO:0051186800.225
purine ribonucleotide metabolic processGO:00091502900.212
carbohydrate biosynthetic processGO:0016051740.208
Rat
carbohydrate derivative biosynthetic processGO:19011371830.197
purine nucleoside triphosphate metabolic processGO:00091442260.183
nucleoside phosphate biosynthetic processGO:1901293790.173
nitrogen compound transportGO:00717052710.172
ribonucleoside monophosphate metabolic processGO:0009161800.165
purine ribonucleoside triphosphate metabolic processGO:00092052200.158
regulation of cofactor metabolic processGO:005119350.156
positive regulation of apoptotic processGO:00430652170.152
purine nucleoside monophosphate metabolic processGO:0009126810.151
mitochondrion organizationGO:00070051340.151
respiratory burstGO:004573080.144
transmembrane transportGO:00550854120.140
purine nucleotide biosynthetic processGO:0006164650.138
4 hydroxyproline metabolic processGO:001947150.136
oxidoreduction coenzyme metabolic processGO:0006733160.135
glycosyl compound biosynthetic processGO:1901659210.134
cellular amide metabolic processGO:0043603580.132
cellular homeostasisGO:00197252400.132
regulation of glycolytic processGO:0006110100.123
cellular response to external stimulusGO:0071496880.120
organonitrogen compound biosynthetic processGO:19015661920.120
ribonucleoside biosynthetic processGO:0042455210.116
ribonucleotide metabolic processGO:00092592910.115
cellular response to extracellular stimulusGO:0031668810.115
syncytium formationGO:0006949430.113
intrinsic apoptotic signaling pathwayGO:00971931320.111
monosaccharide biosynthetic processGO:0046364440.111
Rat
cellular amino acid metabolic processGO:00065201030.109
purine ribonucleoside biosynthetic processGO:0046129190.107
cellular carbohydrate catabolic processGO:0044275150.104
secondary metabolic processGO:0019748180.104
response to oxygen levelsGO:0070482620.089
purine containing compound biosynthetic processGO:0072522700.087
insulin secretionGO:0030073890.087
purine nucleoside metabolic processGO:00422782410.086
regulation of hydrolase activityGO:00513362460.085
carboxylic acid biosynthetic processGO:0046394860.085
apoptotic signaling pathwayGO:00971903060.084
purine ribonucleoside monophosphate metabolic processGO:0009167800.084
organic hydroxy compound biosynthetic processGO:1901617770.083
positive regulation of peptidase activityGO:0010952490.080
regulation of mitochondrial fissionGO:009014030.079
regulation of cellular catabolic processGO:00313292420.079
gluconeogenesisGO:0006094390.077
Rat
apoptotic mitochondrial changesGO:0008637480.077
regulation of nucleotide metabolic processGO:00061401690.075
ion transmembrane transportGO:00342203610.073
purine nucleoside triphosphate biosynthetic processGO:000914570.071
cytoplasmic transportGO:00164822340.069
myotube differentiationGO:00149021050.066
positive regulation of proteolysisGO:0045862850.066
syncytium formation by plasma membrane fusionGO:0000768420.064
organic hydroxy compound metabolic processGO:19016152030.063
response to molecule of bacterial originGO:00022371430.063
nucleotide biosynthetic processGO:0009165780.063
response to heatGO:0009408270.063
small molecule biosynthetic processGO:00442831320.062
heterocycle catabolic processGO:00467002800.062
alpha amino acid metabolic processGO:1901605590.061
pyridine nucleotide metabolic processGO:0019362120.060
myofibril assemblyGO:0030239340.060
ribose phosphate metabolic processGO:00196932910.060
regulation of peptide transportGO:0090087910.060
cell redox homeostasisGO:004545460.059
nicotinamide nucleotide metabolic processGO:0046496120.057
hexose biosynthetic processGO:0019319390.057
Rat
positive regulation of apoptotic signaling pathwayGO:2001235950.056
regulation of intracellular transportGO:00323861590.054
carbohydrate homeostasisGO:00335001280.054
release of cytochrome c from mitochondriaGO:0001836230.054
negative regulation of cellular protein metabolic processGO:00322692470.054
positive regulation of programmed cell deathGO:00430682180.052
regulation of glucose metabolic processGO:0010906600.052
anatomical structure homeostasisGO:00602491450.051
monocarboxylic acid biosynthetic processGO:0072330610.051
regulation of membrane potentialGO:00423911920.049
positive regulation of cellular amino acid metabolic processGO:004576430.048
cation transmembrane transportGO:00986552660.048
pigmentationGO:0043473710.048
organic acid biosynthetic processGO:0016053860.048
cellular nitrogen compound catabolic processGO:00442702800.046
amine metabolic processGO:0009308450.045
regulation of hormone levelsGO:00108172110.044
glucose homeostasisGO:00425931280.043
nucleoside monophosphate biosynthetic processGO:0009124120.043
cellular amine metabolic processGO:0044106440.043
cellular macromolecule catabolic processGO:00442652060.042
reactive oxygen species metabolic processGO:0072593840.042
protein targetingGO:00066051430.041
inorganic cation transmembrane transportGO:00986622070.041
striated muscle cell developmentGO:00550021250.040
response to hypoxiaGO:0001666580.040
regulation of translationGO:0006417710.040
cellular protein complex assemblyGO:00436231160.040
response to organonitrogen compoundGO:00102432460.039
response to oxidative stressGO:00069791230.039
regulation of cellular amino acid metabolic processGO:000652150.037
ribonucleotide biosynthetic processGO:0009260590.037
positive regulation of hydrolase activityGO:00513451480.037
regulation of carbohydrate catabolic processGO:0043470120.037
ribonucleoside metabolic processGO:00091192450.037
muscle cell differentiationGO:00426922610.037
anion transportGO:00068201770.036
cation transportGO:00068123990.036
cellular lipid metabolic processGO:00442553230.036
regulation of protein localizationGO:00328802310.035
protein maturationGO:00516041760.035
organophosphate biosynthetic processGO:00904071220.035
negative regulation of protein metabolic processGO:00512482820.035
response to lipopolysaccharideGO:00324961280.034
ribonucleoside triphosphate metabolic processGO:00091992200.034
positive regulation of cellular amine metabolic processGO:003324050.033
maintenance of locationGO:0051235890.032
regulation of cellular ketone metabolic processGO:0010565660.032
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110110.032
formation of primary germ layerGO:0001704770.031
cellular modified amino acid metabolic processGO:0006575630.031
cellular ketone metabolic processGO:0042180840.031
aromatic compound catabolic processGO:00194392860.031
glucose metabolic processGO:0006006920.031
Rat
regulation of cellular amine metabolic processGO:0033238200.030
regulation of endopeptidase activityGO:0052548890.030
positive regulation of cell deathGO:00109422240.030
regulation of peptidase activityGO:0052547960.030
cellular carbohydrate metabolic processGO:00442621190.030
positive regulation of mapk cascadeGO:00434101700.030
nuclear transportGO:00511691390.030
peptidyl amino acid modificationGO:00181933360.029
regulation of reactive oxygen species metabolic processGO:2000377400.029
glycosyl compound metabolic processGO:19016572460.028
regulation of nucleocytoplasmic transportGO:0046822730.028
regulation of organelle organizationGO:00330432890.027
response to inorganic substanceGO:0010035960.027
midbrain developmentGO:0030901350.027
nuclear importGO:0051170950.027
regulation of ion transmembrane transportGO:00347651190.027
cofactor transportGO:005118140.027
synaptic transmissionGO:00072683290.027
protein catabolic processGO:00301632210.027
response to oxygen radicalGO:0000305160.027
regulation of protein serine threonine kinase activityGO:00719001570.027
hydrogen peroxide metabolic processGO:0042743160.027
positive regulation of growthGO:00459271040.027
cellular response to dna damage stimulusGO:00069742070.026
development of primary sexual characteristicsGO:00451371430.026
regulation of ion transportGO:00432692150.026
cellular component assembly involved in morphogenesisGO:00109271390.026
ribonucleoside catabolic processGO:00424542060.026
epithelial cell proliferationGO:00506731740.026
regulation of establishment of protein localizationGO:00702011810.026
purine ribonucleoside monophosphate biosynthetic processGO:000916890.025
somitogenesisGO:0001756690.025
peptidyl proline hydroxylationGO:001951130.024
regulation of phosphatidylcholine biosynthetic processGO:200124520.024
purine ribonucleotide catabolic processGO:00091542080.024
lateral inhibitionGO:004633110.024
carbohydrate phosphorylationGO:0046835150.023
dna integrity checkpointGO:0031570280.023
regulation of proteolysisGO:00301621640.023
response to extracellular stimulusGO:00099911270.023
monosaccharide catabolic processGO:004636550.023
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.023
carbohydrate derivative catabolic processGO:19011362310.023
pyridine containing compound metabolic processGO:0072524140.023
organelle assemblyGO:00709251770.023
granzyme mediated apoptotic signaling pathwayGO:000862610.023
regulation of protein kinase activityGO:00458592320.023
fat cell differentiationGO:00454441600.023
myosin filament assemblyGO:003103420.022
macromolecule catabolic processGO:00090572810.022
organic anion transportGO:00157111370.022
negative regulation of apoptotic signaling pathwayGO:20012341040.022
cellular response to lipopolysaccharideGO:0071222770.022
cellular response to superoxideGO:0071451140.022
dna metabolic processGO:00062593030.022
regulation of apoptotic signaling pathwayGO:20012331970.021
ribonucleoside triphosphate biosynthetic processGO:000920160.021
positive regulation of protein phosphorylationGO:00019342420.021
cellular ion homeostasisGO:00068731650.021
regulation of protein targetingGO:1903533610.021
cellular response to biotic stimulusGO:0071216920.021
extracellular matrix organizationGO:00301981470.021
nucleoside phosphate catabolic processGO:19012922220.021
cellular response to lipidGO:00713961450.021
positive regulation of protein modification processGO:00314012990.021
intracellular protein transportGO:00068862040.020
mitochondrial membrane organizationGO:0007006260.020
lipid transportGO:0006869980.020
mitotic cell cycleGO:00002781950.020
protein import into nucleusGO:0006606950.020
organonitrogen compound catabolic processGO:19015652640.020
regulation of intracellular protein transportGO:0033157820.020
leukocyte proliferationGO:00706611720.020
regulation of carbohydrate metabolic processGO:0006109750.019
peptidyl serine modificationGO:0018209830.019
spermatogenesisGO:00072832840.019
regulation of cellular carbohydrate metabolic processGO:0010675750.019
cellular response to organonitrogen compoundGO:00714171450.018
adult behaviorGO:00305341350.018
purine ribonucleoside triphosphate biosynthetic processGO:000920660.018
positive regulation of peptide secretionGO:0002793330.018
asymmetric stem cell divisionGO:009872230.018
cellular divalent inorganic cation homeostasisGO:00725031270.018
placenta developmentGO:00018901400.018
removal of superoxide radicalsGO:0019430120.018
negative regulation of cellular amine metabolic processGO:003323910.018
coenzyme biosynthetic processGO:0009108230.018
positive regulation of protein kinase activityGO:00458601440.017
regulation of cellular carbohydrate catabolic processGO:0043471120.017
regulation of generation of precursor metabolites and energyGO:0043467380.017
neuron deathGO:00709971540.017
regulation of cell cycleGO:00517262810.017
positive regulation of mitochondrion organizationGO:0010822170.017
translationGO:0006412930.017
purine containing compound catabolic processGO:00725232130.017
immune effector processGO:00022523210.017
single organism nuclear importGO:1902593950.017
positive regulation of kinase activityGO:00336741550.016
inorganic ion transmembrane transportGO:00986602340.016
superoxide metabolic processGO:0006801270.016
sensory perceptionGO:00076002450.016
cellular response to carbohydrate stimulusGO:0071322500.016
cellularizationGO:000734910.016
positive regulation of hormone secretionGO:0046887380.016
regulation of cell activationGO:00508652890.016
negative regulation of cell proliferationGO:00082852960.016
regulation of mitochondrion organizationGO:0010821270.016
protein processingGO:00164851630.016
positive regulation of cysteine type endopeptidase activityGO:2001056390.016
regulation of protein transportGO:00512231630.016
mesoderm formationGO:0001707620.016
organelle localizationGO:00516401790.016
negative regulation of translationGO:0017148220.016
lymphocyte proliferationGO:00466511640.015
homeostasis of number of cellsGO:00488722100.015
l ascorbic acid metabolic processGO:001985240.015
sulfur compound metabolic processGO:00067901000.015
determination of adult lifespanGO:0008340110.015
mapk cascadeGO:00001652810.015
regulation of mapk cascadeGO:00434082480.015
pyridine nucleotide biosynthetic processGO:001936340.015
protein importGO:00170381010.015
cellular response to hormone stimulusGO:00328701500.015
divalent inorganic cation homeostasisGO:00725071380.015
regulation of cysteine type endopeptidase activityGO:2000116650.015
regulation of transmembrane transportGO:00347621280.015
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
actomyosin structure organizationGO:0031032560.015
inflammatory responseGO:00069542440.015
protein localization to nucleusGO:00345041210.015
glycerolipid metabolic processGO:00464861220.015
purine nucleoside catabolic processGO:00061522050.015
activation of cysteine type endopeptidase activityGO:0097202270.015
purine nucleotide catabolic processGO:00061952110.014
regulation of reactive oxygen species biosynthetic processGO:190342620.014
regulation of transferase activityGO:00513382630.014
cellular respirationGO:0045333380.014
regulation of cellular response to stressGO:00801351590.014
negative regulation of membrane potentialGO:004583740.014
regulation of cytokine productionGO:00018172660.014
negative regulation of t cell activationGO:0050868650.014
genitalia developmentGO:0048806370.014
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.014
regulation of protein import into nucleusGO:0042306520.014
action potentialGO:0001508780.014
adenine nucleotide transportGO:005150320.014
positive regulation of reactive oxygen species metabolic processGO:2000379110.014
heart morphogenesisGO:00030071780.014
forebrain developmentGO:00309003020.013
myeloid cell differentiationGO:00300992330.013
male gamete generationGO:00482322850.013
membrane organizationGO:00610242450.013
galactose metabolic processGO:000601240.013
regulation of cytoplasmic transportGO:19036491120.013
neural tube formationGO:00018411080.013
organophosphate catabolic processGO:00464342320.013
innate immune responseGO:00450871570.013
response to organic cyclic compoundGO:00140701980.013
nucleotide catabolic processGO:00091662170.013
negative regulation of cell cycle phase transitionGO:1901988480.013
gonad developmentGO:00084061410.013
cellular response to oxygen levelsGO:0071453200.013
nucleoside catabolic processGO:00091642060.013
cation homeostasisGO:00550802120.013
tissue homeostasisGO:00018941150.013
spermatid developmentGO:00072861080.013
purine ribonucleoside catabolic processGO:00461302050.013
mitotic cell cycle checkpointGO:0007093310.013
skin developmentGO:00435882200.013
regulation of anion transportGO:0044070270.013
divalent metal ion transportGO:00708381720.013
purine nucleobase biosynthetic processGO:000911330.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.012
cellular response to molecule of bacterial originGO:0071219830.012
metal ion homeostasisGO:00550651890.012
negative regulation of phosphorylationGO:00423261660.012
striated muscle contractionGO:0006941450.012
regulation of phospholipid biosynthetic processGO:007107130.012
negative regulation of lymphocyte activationGO:0051250910.012
nucleic acid phosphodiester bond hydrolysisGO:0090305490.012
nucleoside monophosphate catabolic processGO:0009125590.012
response to increased oxygen levelsGO:003629620.012
response to radiationGO:00093141650.012
ribonucleoside monophosphate catabolic processGO:0009158570.012
negative regulation of molecular functionGO:00440922580.012
epithelial cell developmentGO:00020641590.012
nucleocytoplasmic transportGO:00069131390.012
organic cyclic compound catabolic processGO:19013612950.012
divalent inorganic cation transportGO:00725111780.012
positive regulation of mitochondrial fissionGO:009014120.012
amide transportGO:00428861380.012
purine nucleobase metabolic processGO:000614440.012
alcohol metabolic processGO:00060661160.012
spindle assembly involved in mitosisGO:009030740.012
muscle cell developmentGO:00550011330.012
regulation of transporter activityGO:0032409570.012
reactive nitrogen species metabolic processGO:200105700.012
cellular response to oxygen radicalGO:0071450140.012
regulation of secretion by cellGO:19035302490.012
protein secretionGO:00093061110.012
mitochondrion distributionGO:004831140.012
cell type specific apoptotic processGO:00972852680.012
calcium ion homeostasisGO:00550741270.012
positive regulation of endopeptidase activityGO:0010950430.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.011
organic hydroxy compound transportGO:0015850930.011
regulation of kinase activityGO:00435492490.011
cellular metal ion homeostasisGO:00068751510.011
t cell activationGO:00421102890.011
axonogenesisGO:00074092740.011
reactive oxygen species biosynthetic processGO:190340980.011
response to alcoholGO:0097305480.011
retina homeostasisGO:0001895230.011
cellular response to peptide hormone stimulusGO:0071375920.011
response to acid chemicalGO:00011011110.011
multicellular organismal homeostasisGO:00488711640.011
response to nicotineGO:003509460.011
hexose transmembrane transportGO:003542870.011
sequestering of metal ionGO:0051238190.011
protein homotetramerizationGO:0051289120.011
leukocyte mediated cytotoxicityGO:0001909620.011
cell killingGO:0001906670.011
myeloid cell homeostasisGO:00022621140.011
molting cycleGO:0042303900.011
cellular response to peptideGO:1901653920.011
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108140.011
spermatid differentiationGO:00485151150.011
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.011
glycosyl compound catabolic processGO:19016582060.011
regulation of interleukin 8 productionGO:003267730.011
negative regulation of intracellular signal transductionGO:19025321670.011
positive regulation of response to woundingGO:1903036660.011
epithelial tube morphogenesisGO:00605623030.011
l glutamate uptake involved in synaptic transmissionGO:005193530.011
regulation of atp biosynthetic processGO:200116930.011
cellular response to monosaccharide stimulusGO:0071326470.011
calcium ion transmembrane transportGO:0070588850.011
ras protein signal transductionGO:0007265770.011
extracellular structure organizationGO:00430621480.011
purine ribonucleotide biosynthetic processGO:0009152590.011
gland developmentGO:00487323300.011
positive regulation of transferase activityGO:00513471670.011
lipid biosynthetic processGO:00086101790.010
regulation of lymphocyte activationGO:00512492400.010
sequestering of calcium ionGO:0051208180.010
muscle system processGO:00030121410.010
cell fate commitmentGO:00451652100.010
lipid localizationGO:00108761260.010
peptidyl serine phosphorylationGO:0018105740.010
regulation of response to woundingGO:19030341890.010
protein localization to organelleGO:00333651850.010
protein export from nucleusGO:0006611200.010
cellular response to insulin stimulusGO:0032869780.010
regulation of mitochondrial membrane permeabilityGO:0046902170.010
response to insulinGO:00328681000.010
regulation of body fluid levelsGO:00508781620.010
blood vessel morphogenesisGO:00485142850.010
stress activated protein kinase signaling cascadeGO:0031098810.010
regulation of leukocyte differentiationGO:19021051590.010
negative regulation of cellular component organizationGO:00511291940.010
purine ribonucleoside monophosphate catabolic processGO:0009169570.010

Pgk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.372
carbohydrate metabolism diseaseDOID:005001300.198
acquired metabolic diseaseDOID:006015800.198
disease of anatomical entityDOID:700.118
immune system diseaseDOID:291400.118
hematopoietic system diseaseDOID:7400.050
nervous system diseaseDOID:86300.044
blood coagulation diseaseDOID:124700.022
glucose metabolism diseaseDOID:419400.015
central nervous system diseaseDOID:33100.015
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
musculoskeletal system diseaseDOID:1700.011