Mus musculus

154 known processes

Hells

helicase, lymphoid specific

(Aliases: Lysh,PASG,LSH,E130115I21Rik,YFK8,AI323785)

Hells biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna methylation involved in gamete generationGO:0043046150.997
hypermethylation of cpg islandGO:004402730.973
dna hypermethylationGO:004402630.968
double strand break repairGO:0006302480.944
dna metabolic processGO:00062593030.939
dna repairGO:00062811070.930
chorion developmentGO:006071770.849
meiosis iGO:0007127600.810
cellular response to dna damage stimulusGO:00069742070.779
dna replicationGO:0006260520.745
purine nucleoside triphosphate catabolic processGO:00091462030.718
meiotic cell cycleGO:00513211220.697
dna modificationGO:0006304500.693
meiotic cell cycle processGO:1903046770.688
negative regulation of cell cycle processGO:0010948690.676
heterocycle catabolic processGO:00467002800.657
dna methylationGO:0006306430.636
recombinational repairGO:0000725210.630
negative regulation of cell cycleGO:00457861230.611
double strand break repair via homologous recombinationGO:0000724210.611
cellular macromolecule catabolic processGO:00442652060.555
cell cycle checkpointGO:0000075470.511
synapsisGO:0007129340.487
organic cyclic compound catabolic processGO:19013612950.451
negative regulation of mitotic cell cycle phase transitionGO:1901991450.429
purine ribonucleotide metabolic processGO:00091502900.426
nucleoside phosphate metabolic processGO:00067533380.425
regulation of cell cycle processGO:00105641600.407
purine nucleotide metabolic processGO:00061633020.405
ribonucleoside triphosphate catabolic processGO:00092031990.398
dna geometric changeGO:003239270.396
nucleoside metabolic processGO:00091162460.394
negative regulation of cellular component organizationGO:00511291940.386
nucleoside triphosphate metabolic processGO:00091412300.379
reciprocal dna recombinationGO:0035825160.377
aromatic compound catabolic processGO:00194392860.368
negative regulation of cell cycle phase transitionGO:1901988480.363
glycosyl compound metabolic processGO:19016572460.350
cellular nitrogen compound catabolic processGO:00442702800.343
regulation of dna replicationGO:0006275170.339
chromosome organization involved in meiosisGO:0070192390.332
ribonucleoside triphosphate metabolic processGO:00091992200.323
ribose phosphate metabolic processGO:00196932910.312
ribonucleoside metabolic processGO:00091192450.310
purine ribonucleoside triphosphate catabolic processGO:00092071990.304
gonad developmentGO:00084061410.302
purine nucleoside catabolic processGO:00061522050.301
mitotic cell cycle processGO:19030471590.299
organonitrogen compound catabolic processGO:19015652640.297
purine containing compound metabolic processGO:00725213110.292
cellular response to organonitrogen compoundGO:00714171450.278
meiotic nuclear divisionGO:00071261150.276
nucleobase containing small molecule metabolic processGO:00550863520.276
regulation of cell cycle g2 m phase transitionGO:1902749100.273
glycosyl compound catabolic processGO:19016582060.273
purine nucleoside triphosphate metabolic processGO:00091442260.264
purine ribonucleoside triphosphate metabolic processGO:00092052200.263
ribonucleotide metabolic processGO:00092592910.263
purine nucleoside metabolic processGO:00422782410.258
negative regulation of protein metabolic processGO:00512482820.255
positive regulation of histone h3 k4 methylationGO:005157150.251
nucleoside monophosphate metabolic processGO:0009123850.250
histone methylationGO:0016571710.247
methylationGO:00322591340.244
spermatogenesisGO:00072832840.244
dna recombinationGO:0006310920.243
Yeast
regulation of chromosome organizationGO:0033044830.236
ribonucleotide catabolic processGO:00092612080.236
negative regulation of nuclear divisionGO:0051784190.221
purine ribonucleotide catabolic processGO:00091542080.219
purine nucleotide catabolic processGO:00061952110.219
carbohydrate derivative catabolic processGO:19011362310.217
dna dependent dna replicationGO:0006261240.216
regulation of mitotic cell cycle phase transitionGO:1901990730.211
nucleoside catabolic processGO:00091642060.209
dna alkylationGO:0006305430.206
purine ribonucleoside metabolic processGO:00461282410.206
organelle fissionGO:00482851700.202
nucleotide catabolic processGO:00091662170.193
regulation of hydrolase activityGO:00513362460.192
mitotic cell cycleGO:00002781950.176
microtubule cytoskeleton organizationGO:00002261570.175
nucleoside triphosphate catabolic processGO:00091432050.173
regulation of cell cycleGO:00517262810.169
regulation of dna methylationGO:0044030120.166
male gamete generationGO:00482322850.165
mitotic g2 dna damage checkpointGO:000709580.154
regulation of cell cycle phase transitionGO:1901987770.153
meiotic chromosome segregationGO:0045132190.149
dna methylation involved in embryo developmentGO:004304560.146
nucleotide metabolic processGO:00091173320.143
macromolecule methylationGO:00434141200.143
ribonucleoside catabolic processGO:00424542060.142
histone h3 k9 methylationGO:0051567170.139
protein methylationGO:0006479810.139
regulation of histone h3 k4 methylationGO:0051569120.138
female meiosis chromosome segregationGO:001632110.138
positive regulation of histone methylationGO:0031062160.134
nucleoside phosphate catabolic processGO:19012922220.133
regulation of cell divisionGO:0051302760.132
dosage compensation by inactivation of x chromosomeGO:000904870.130
negative regulation of histone methylationGO:0031061100.126
negative regulation of histone h3 k9 methylationGO:005157340.125
regulation of gene expression by genetic imprintingGO:0006349150.125
response to organonitrogen compoundGO:00102432460.123
negative regulation of mitotic cell cycleGO:0045930580.122
regulation of histone h3 k9 methylationGO:005157080.119
chromatin organizationGO:00063252060.118
regulation of organelle organizationGO:00330432890.118
dna endoreduplicationGO:004202340.117
histone lysine methylationGO:0034968500.116
development of primary sexual characteristicsGO:00451371430.116
nucleic acid phosphodiester bond hydrolysisGO:0090305490.116
genetic imprintingGO:0071514270.115
chromatin modificationGO:00165681870.114
dna catabolic processGO:0006308190.112
protein modification by small protein conjugation or removalGO:00706472070.111
double strand break repair via nonhomologous end joiningGO:0006303100.109
histone acetylationGO:0016573410.108
changes to dna methylation involved in embryo developmentGO:190153860.107
nuclear divisionGO:00002801580.107
negative regulation of gene expression epigeneticGO:0045814150.106
negative regulation of dna replicationGO:000815640.104
response to radiationGO:00093141650.104
dna methylation on cytosineGO:003277650.097
dna catabolic process exonucleolyticGO:000073830.096
positive regulation of apoptotic processGO:00430652170.095
macromolecule catabolic processGO:00090572810.092
organophosphate catabolic processGO:00464342320.091
purine nucleoside monophosphate metabolic processGO:0009126810.091
regulation of chromatin modificationGO:1903308570.090
organelle assemblyGO:00709251770.090
intrinsic apoptotic signaling pathwayGO:00971931320.089
genitalia developmentGO:0048806370.087
female meiotic divisionGO:0007143210.083
maintenance of locationGO:0051235890.082
purine nucleoside monophosphate catabolic processGO:0009128580.082
reciprocal meiotic recombinationGO:0007131160.081
purine ribonucleoside catabolic processGO:00461302050.080
camera type eye developmentGO:00430102660.080
ribonucleoside monophosphate metabolic processGO:0009161800.080
apoptotic signaling pathwayGO:00971903060.078
regulation of meiosis iGO:006063170.077
dna catabolic process endonucleolyticGO:0000737150.076
microtubule based processGO:00070172360.076
histone threonine phosphorylationGO:003540510.072
gene silencingGO:0016458380.071
response to organic cyclic compoundGO:00140701980.070
chorionic trophoblast cell differentiationGO:006071850.068
protein modification by small protein conjugationGO:00324461870.067
positive regulation of chromatin modificationGO:1903310280.067
atp metabolic processGO:0046034750.066
purine ribonucleoside monophosphate metabolic processGO:0009167800.064
translesion synthesisGO:001998510.064
heterochromatin organizationGO:007082840.063
protein alkylationGO:0008213810.062
cellular ketone metabolic processGO:0042180840.060
retina development in camera type eyeGO:00600411190.060
microtubule organizing center organizationGO:0031023280.058
cellular response to acid chemicalGO:0071229680.058
endocytosisGO:00068971680.057
regulation of cellular amino acid metabolic processGO:000652150.057
regulation of mitotic cell cycleGO:00073461260.056
ubiquitin dependent protein catabolic processGO:00065111290.056
mitotic recombinationGO:000631230.056
Yeast
cellular protein catabolic processGO:00442571550.056
cellular response to organic cyclic compoundGO:0071407870.055
histone h3 k4 methylationGO:0051568230.053
regulation of histone modificationGO:0031056560.053
response to ionizing radiationGO:0010212420.052
regulation of nucleotide metabolic processGO:00061401690.052
negative regulation of organelle organizationGO:0010639900.052
placenta developmentGO:00018901400.052
ribonucleoside monophosphate catabolic processGO:0009158570.051
chromatin silencingGO:0006342150.051
protein catabolic processGO:00301632210.050
g2 dna damage checkpointGO:003157280.048
membrane organizationGO:00610242450.047
nucleoside monophosphate catabolic processGO:0009125590.046
regulation of cellular catabolic processGO:00313292420.046
purine containing compound catabolic processGO:00725232130.046
regulation of dna dependent dna replicationGO:009032980.045
meiotic cell cycle checkpointGO:003331320.045
negative regulation of chromosome organizationGO:2001251300.045
cellular amine metabolic processGO:0044106440.044
germ cell developmentGO:00072811850.044
cell divisionGO:00513011200.044
regulation of histone methylationGO:0031060300.044
nuclear dna replicationGO:003326030.042
positive regulation of cell cycle phase transitionGO:1901989170.042
regulation of mitosisGO:0007088290.041
male meiosisGO:0007140370.041
regulation of centriole replicationGO:004659910.040
non recombinational repairGO:0000726100.040
dna integrity checkpointGO:0031570280.040
spindle assembly involved in female meiosisGO:000705630.039
atp catabolic processGO:0006200550.039
response to amino acidGO:0043200370.039
cellular amino acid metabolic processGO:00065201030.039
negative regulation of cellular protein metabolic processGO:00322692470.038
digestive system developmentGO:00551232000.038
positive regulation of programmed cell deathGO:00430682180.038
positive regulation of hydrolase activityGO:00513451480.038
regulation of nucleoside metabolic processGO:00091181300.037
receptor mediated endocytosisGO:0006898510.036
purine ribonucleoside monophosphate catabolic processGO:0009169570.034
mitotic cell cycle checkpointGO:0007093310.034
regulation of cellular amine metabolic processGO:0033238200.033
dna damage checkpointGO:0000077260.033
dna duplex unwindingGO:003250870.032
regulation of dna recombinationGO:0000018340.032
covalent chromatin modificationGO:00165691630.031
regulation of cellular ketone metabolic processGO:0010565660.031
meiotic dna double strand break formationGO:004213830.031
cellular response to amino acid stimulusGO:0071230290.031
response to acid chemicalGO:00011011110.031
regulation of purine nucleotide metabolic processGO:19005421690.030
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.029
positive regulation of cell developmentGO:00107202370.029
response to light stimulusGO:00094161350.028
regulation of transcription by chromatin organizationGO:003440100.028
chromosome segregationGO:0007059480.028
neural retina developmentGO:0003407410.028
regulation of transferase activityGO:00513382630.027
dna ligationGO:000626630.027
neuron migrationGO:00017641220.026
positive regulation of nucleotide metabolic processGO:00459811140.026
eye photoreceptor cell differentiationGO:0001754410.026
negative regulation of cell divisionGO:0051782240.026
proteolysis involved in cellular protein catabolic processGO:00516031470.025
regulation of chromatin organizationGO:1902275570.025
engulfment of apoptotic cellGO:004365230.025
negative regulation of meiotic cell cycle phase transitionGO:190199430.024
nucleocytoplasmic transportGO:00069131390.024
intra s dna damage checkpointGO:003157340.024
dna unwinding involved in dna replicationGO:000626850.023
female gamete generationGO:0007292740.023
positive regulation of lymphocyte activationGO:00512511400.022
amine metabolic processGO:0009308450.022
organophosphate biosynthetic processGO:00904071220.022
multicellular organism growthGO:00352641610.022
mitochondrion organizationGO:00070051340.021
response to alkaloidGO:0043279340.021
positive regulation of gtp catabolic processGO:0033126850.021
protein import into nucleusGO:0006606950.021
peptidyl amino acid modificationGO:00181933360.021
dna biosynthetic processGO:0071897220.021
positive regulation of cell cycle processGO:0090068610.021
mitochondrial genome maintenanceGO:0000002150.020
positive regulation of cell deathGO:00109422240.020
cellular response to abiotic stimulusGO:0071214560.020
regulation of purine nucleotide catabolic processGO:00331211220.020
protein processingGO:00164851630.019
regulation of cell activationGO:00508652890.019
protein maturationGO:00516041760.019
regulation of nucleotide catabolic processGO:00308111220.019
meiotic chromosome condensationGO:001003230.019
negative regulation of meiotic cell cycleGO:0051447140.019
positive regulation of cellular catabolic processGO:00313311480.018
protein oligomerizationGO:0051259670.018
establishment of organelle localizationGO:00516561220.018
rna dependent dna replicationGO:000627830.018
response to purine containing compoundGO:0014074280.018
regulation of protein localizationGO:00328802310.018
spindle organizationGO:0007051280.017
sensory organ morphogenesisGO:00905962420.017
oxidation reduction processGO:00551143420.017
dna replication initiationGO:000627050.017
regulation of nuclear cell cycle dna replicationGO:003326220.017
peptidyl lysine modificationGO:0018205770.017
membrane invaginationGO:0010324170.017
spermatid differentiationGO:00485151150.017
retina morphogenesis in camera type eyeGO:0060042450.017
positive regulation of histone h3 k9 methylationGO:005157440.016
protein ubiquitinationGO:00165671710.016
cell cycle g1 s phase transitionGO:0044843570.016
ras protein signal transductionGO:0007265770.016
regulation of lymphocyte activationGO:00512492400.016
cell fate commitmentGO:00451652100.016
protein acylationGO:0043543640.016
positive regulation of cellular amine metabolic processGO:003324050.016
response to caffeineGO:003100060.015
positive regulation of protein modification processGO:00314012990.015
regulation of asymmetric cell divisionGO:000978640.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
cellular protein complex assemblyGO:00436231160.015
regulation of apoptotic signaling pathwayGO:20012331970.015
forebrain developmentGO:00309003020.015
histone h4 k20 trimethylationGO:003477320.015
negative regulation of protein maturationGO:1903318790.015
intracellular protein transportGO:00068862040.015
anatomical structure homeostasisGO:00602491450.015
cell type specific apoptotic processGO:00972852680.015
response to inorganic substanceGO:0010035960.015
rna interferenceGO:001624620.015
regulation of neuron differentiationGO:00456642810.015
interspecies interaction between organismsGO:0044419830.015
regulation of cellular response to stressGO:00801351590.015
guanosine containing compound catabolic processGO:19010691440.015
exocrine system developmentGO:0035272450.014
positive regulation of cellular amino acid metabolic processGO:004576430.014
protein localization to nucleusGO:00345041210.014
mitochondrial dna replicationGO:000626470.014
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.014
establishment of protein localization to organelleGO:00725941180.014
dna conformation changeGO:0071103370.014
nucleoside phosphate biosynthetic processGO:1901293790.014
regulation of rho protein signal transductionGO:0035023710.014
mitotic nuclear divisionGO:0007067480.014
cellularizationGO:000734910.014
synaptonemal complex assemblyGO:0007130130.014
rho protein signal transductionGO:0007266320.014
positive regulation of histone modificationGO:0031058280.014
regulation of intracellular transportGO:00323861590.014
positive regulation of cellular component biogenesisGO:0044089940.014
actin mediated cell contractionGO:0070252150.014
sister chromatid segregationGO:0000819200.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
modification dependent protein catabolic processGO:00199411330.013
cellular response to cytokine stimulusGO:00713451890.013
gene silencing by rnaGO:0031047190.013
actin cytoskeleton organizationGO:00300362200.013
negative regulation of mitosisGO:0045839100.013
cellular response to oxidative stressGO:0034599760.013
regulation of cellular component biogenesisGO:00440871810.013
peptidyl lysine acetylationGO:0018394450.012
striated muscle myosin thick filament assemblyGO:007168810.012
guanosine containing compound metabolic processGO:19010681440.012
negative regulation of hydrolase activityGO:0051346710.012
single organism nuclear importGO:1902593950.012
regulation of peptidase activityGO:0052547960.012
response to steroid hormoneGO:0048545560.012
chromatin mediated maintenance of transcriptionGO:004809620.012
mitotic sister chromatid cohesionGO:000706410.012
positive regulation of nervous system developmentGO:00519622210.012
posttranscriptional gene silencingGO:0016441100.012
female meiosis iGO:000714470.012
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.012
cellular response to ionizing radiationGO:0071479110.012
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.012
regulation of cell projection organizationGO:00313442060.012
cellular response to external stimulusGO:0071496880.012
cellular response to hormone stimulusGO:00328701500.011
regulation of neural precursor cell proliferationGO:2000177700.011
regulation of microtubule based processGO:0032886520.011
spindle assembly involved in meiosisGO:009030640.011
regulation of neuron projection developmentGO:00109751690.011
chromatin assembly or disassemblyGO:0006333160.011
negative regulation of proteolysisGO:0045861740.011
wnt signaling pathwayGO:00160551880.011
base excision repairGO:000628490.011
negative regulation of neuron deathGO:1901215980.011
protein targetingGO:00066051430.011
negative regulation of dna dependent dna replicationGO:200010410.011
neural precursor cell proliferationGO:00613511210.011
response to metal ionGO:0010038470.011
regulation of canonical wnt signaling pathwayGO:0060828820.011
protein complex localizationGO:0031503190.011
regulation of actin filament based processGO:0032970990.011
positive regulation of growthGO:00459271040.011
positive regulation of cell cycleGO:0045787920.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
pancreas developmentGO:0031016570.011
production of molecular mediator of immune responseGO:00024401030.011
actomyosin structure organizationGO:0031032560.011
axonogenesisGO:00074092740.011
response to oxidative stressGO:00069791230.011
regulation of protein maturationGO:1903317960.010
positive regulation of nucleoside metabolic processGO:0045979910.010
cell maturationGO:00484691270.010
nuclear transportGO:00511691390.010
regulation of cytoplasmic transportGO:19036491120.010
regulation of vesicle mediated transportGO:00606271390.010
regulation of ras protein signal transductionGO:00465781140.010
inner cell mass cell proliferationGO:0001833150.010
leukocyte differentiationGO:00025213420.010
negative regulation of sister chromatid segregationGO:003304670.010
blastocyst developmentGO:0001824800.010
proteasomal protein catabolic processGO:0010498980.010
intracellular mrna localizationGO:000829840.010
response to hypoxiaGO:0001666580.010
nucleus organizationGO:0006997450.010
cytoplasmic transportGO:00164822340.010
lipid localizationGO:00108761260.010

Hells disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.024
cancerDOID:16200.024
thoracic cancerDOID:509300.024
organ system cancerDOID:005068600.024
physical disorderDOID:008001500.015
breast cancerDOID:161200.013