| protein modification by small protein removal | GO:0070646 | 21 | 0.617 | Human |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.107 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.100 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.076 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.069 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.066 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.061 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.058 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.057 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.055 | |
| lateral inhibition | GO:0046331 | 1 | 0.055 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.052 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.051 | |
| membrane organization | GO:0061024 | 245 | 0.050 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.050 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.050 | |
| amine metabolic process | GO:0009308 | 45 | 0.047 | |
| oocyte axis specification | GO:0007309 | 2 | 0.046 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.045 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.044 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.044 | |
| mrna splicing via spliceosome | GO:0000398 | 43 | 0.044 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.042 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.039 | |
| cell division | GO:0051301 | 120 | 0.039 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.038 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.038 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.037 | |
| rna splicing via transesterification reactions | GO:0000375 | 43 | 0.037 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.037 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.036 | |
| oocyte construction | GO:0007308 | 2 | 0.034 | |
| blastocyst development | GO:0001824 | 80 | 0.033 | |
| mitotic cell cycle checkpoint | GO:0007093 | 31 | 0.033 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.032 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.032 | |
| mrna metabolic process | GO:0016071 | 84 | 0.032 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.032 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.032 | |
| mrna processing | GO:0006397 | 63 | 0.031 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.031 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.030 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.030 | |
| mapk cascade | GO:0000165 | 281 | 0.027 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.026 | Human |
| cell fate commitment | GO:0045165 | 210 | 0.026 | |
| localization within membrane | GO:0051668 | 4 | 0.026 | |
| stem cell development | GO:0048864 | 219 | 0.025 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.025 | |
| axonogenesis | GO:0007409 | 274 | 0.025 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.024 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.024 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.024 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.024 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.024 | |
| endocytosis | GO:0006897 | 168 | 0.024 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.024 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.023 | Human |
| mitotic cell cycle | GO:0000278 | 195 | 0.023 | |
| fertilization | GO:0009566 | 127 | 0.023 | |
| cell maturation | GO:0048469 | 127 | 0.023 | |
| rna splicing | GO:0008380 | 54 | 0.022 | |
| protein hydroxylation | GO:0018126 | 4 | 0.022 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.022 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.022 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.022 | Human |
| cytokinesis | GO:0000910 | 17 | 0.021 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.021 | |
| camera type eye development | GO:0043010 | 266 | 0.021 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.021 | |
| stem cell differentiation | GO:0048863 | 268 | 0.021 | |
| synaptic transmission | GO:0007268 | 329 | 0.021 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.021 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.020 | |
| rna processing | GO:0006396 | 105 | 0.020 | |
| germ cell development | GO:0007281 | 185 | 0.020 | |
| organelle assembly | GO:0070925 | 177 | 0.020 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.020 | |
| developmental maturation | GO:0021700 | 193 | 0.020 | |
| regulation of cell division | GO:0051302 | 76 | 0.020 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.020 | |
| actomyosin structure organization | GO:0031032 | 56 | 0.020 | |
| cation transport | GO:0006812 | 399 | 0.019 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.019 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.019 | |
| protein localization to organelle | GO:0033365 | 185 | 0.019 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 4 | 0.019 | |
| nuclear import | GO:0051170 | 95 | 0.019 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.019 | |
| protein stabilization | GO:0050821 | 25 | 0.019 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.019 | Human |
| protein ubiquitination | GO:0016567 | 171 | 0.018 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.018 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.018 | |
| mitochondrion organization | GO:0007005 | 134 | 0.018 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.018 | |
| regulation of protein stability | GO:0031647 | 52 | 0.018 | |
| oogenesis | GO:0048477 | 56 | 0.018 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.017 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.017 | |
| cytokine production | GO:0001816 | 319 | 0.017 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.017 | |
| regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045898 | 2 | 0.017 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.017 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.017 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.017 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.017 | |
| response to acid chemical | GO:0001101 | 111 | 0.017 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.017 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.017 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.016 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.016 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.016 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.016 | |
| lipid localization | GO:0010876 | 126 | 0.016 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.016 | Human |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.016 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.016 | Human |
| protein import into nucleus | GO:0006606 | 95 | 0.016 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.016 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.016 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.016 | |
| organelle localization | GO:0051640 | 179 | 0.016 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.016 | |
| protein dna complex subunit organization | GO:0071824 | 28 | 0.016 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.015 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.015 | |
| organelle membrane fusion | GO:0090174 | 1 | 0.015 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.015 | |
| single fertilization | GO:0007338 | 82 | 0.015 | |
| oocyte development | GO:0048599 | 33 | 0.015 | |
| cytokinetic process | GO:0032506 | 2 | 0.015 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.015 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.015 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.015 | |
| macromolecule methylation | GO:0043414 | 120 | 0.014 | |
| atp catabolic process | GO:0006200 | 55 | 0.014 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.014 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.014 | |
| maturation of 5 8s rrna | GO:0000460 | 1 | 0.014 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.014 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.014 | |
| dna damage checkpoint | GO:0000077 | 26 | 0.014 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.014 | |
| ribosomal small subunit biogenesis | GO:0042274 | 4 | 0.013 | |
| intracellular protein transport | GO:0006886 | 204 | 0.013 | |
| pole plasm assembly | GO:0007315 | 2 | 0.013 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.013 | |
| maintenance of location | GO:0051235 | 89 | 0.013 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.013 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.013 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.013 | |
| intracellular mrna localization | GO:0008298 | 4 | 0.013 | |
| male gamete generation | GO:0048232 | 285 | 0.013 | |
| steroid metabolic process | GO:0008202 | 119 | 0.013 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.013 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.013 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.013 | |
| cell recognition | GO:0008037 | 83 | 0.013 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.013 | |
| nuclear transport | GO:0051169 | 139 | 0.012 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.012 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.012 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.012 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.012 | |
| central nervous system neuron differentiation | GO:0021953 | 162 | 0.012 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.012 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.012 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.012 | |
| inflammatory response | GO:0006954 | 244 | 0.012 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.012 | |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.012 | |
| skeletal system development | GO:0001501 | 356 | 0.012 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.012 | |
| positive regulation of protein ubiquitination | GO:0031398 | 27 | 0.012 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.012 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.012 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.012 | |
| muscle cell development | GO:0055001 | 133 | 0.012 | |
| histone modification | GO:0016570 | 159 | 0.012 | |
| respiratory system development | GO:0060541 | 190 | 0.012 | |
| organelle fission | GO:0048285 | 170 | 0.012 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 19 | 0.012 | |
| stem cell maintenance | GO:0019827 | 130 | 0.011 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.011 | |
| protein catabolic process | GO:0030163 | 221 | 0.011 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.011 | |
| alcohol metabolic process | GO:0006066 | 116 | 0.011 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.011 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.011 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.011 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.011 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.011 | |
| cell adhesion | GO:0007155 | 329 | 0.011 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.011 | |
| regionalization | GO:0003002 | 337 | 0.011 | |
| connective tissue development | GO:0061448 | 179 | 0.011 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.011 | |
| inner cell mass cell proliferation | GO:0001833 | 15 | 0.011 | |
| protein import | GO:0017038 | 101 | 0.011 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.011 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.011 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.011 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.011 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 59 | 0.011 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.010 | |
| spermatogenesis | GO:0007283 | 284 | 0.010 | |
| locomotory behavior | GO:0007626 | 195 | 0.010 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.010 | |
| regulation of secretion | GO:0051046 | 274 | 0.010 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.010 | |
| methylation | GO:0032259 | 134 | 0.010 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.010 | |
| organic hydroxy compound transport | GO:0015850 | 93 | 0.010 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.010 | |
| striated muscle myosin thick filament assembly | GO:0071688 | 1 | 0.010 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.010 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.010 | |
| cell differentiation in spinal cord | GO:0021515 | 53 | 0.010 | |
| negative regulation of tor signaling | GO:0032007 | 13 | 0.010 | |