Mus musculus

85 known processes

Cops2

COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)

(Aliases: Sgn2,C85265,alien-like,Csn2,AI315723,Trip15)

Cops2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecule catabolic processGO:00090572810.829
ubiquitin dependent protein catabolic processGO:00065111290.716
proteasomal protein catabolic processGO:0010498980.715
cellular protein catabolic processGO:00442571550.623
glycosyl compound catabolic processGO:19016582060.474
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.459
protein neddylationGO:004511610.454
ribonucleotide catabolic processGO:00092612080.442
protein catabolic processGO:00301632210.436
proteolysis involved in cellular protein catabolic processGO:00516031470.360
modification dependent protein catabolic processGO:00199411330.357
cellular macromolecule catabolic processGO:00442652060.357
mitotic cell cycleGO:00002781950.343
cellular response to dna damage stimulusGO:00069742070.335
regulation of cell cycleGO:00517262810.328
chromosome segregationGO:0007059480.286
nucleotide catabolic processGO:00091662170.284
purine nucleotide catabolic processGO:00061952110.258
guanosine containing compound metabolic processGO:19010681440.237
regulation of mitotic cell cycleGO:00073461260.235
regulation of cell cycle processGO:00105641600.234
multicellular organismal protein catabolic processGO:004425410.225
purine ribonucleotide metabolic processGO:00091502900.225
positive regulation of cellular catabolic processGO:00313311480.220
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.208
protein modification by small protein conjugation or removalGO:00706472070.197
Human
glycosyl compound metabolic processGO:19016572460.194
carbohydrate derivative catabolic processGO:19011362310.192
ribonucleoside triphosphate catabolic processGO:00092031990.191
ribonucleoside catabolic processGO:00424542060.190
purine ribonucleoside catabolic processGO:00461302050.184
purine ribonucleotide catabolic processGO:00091542080.173
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.170
establishment of protein localization to organelleGO:00725941180.170
protein targetingGO:00066051430.163
purine ribonucleoside metabolic processGO:00461282410.162
nucleotide metabolic processGO:00091173320.154
organonitrogen compound catabolic processGO:19015652640.151
modification dependent macromolecule catabolic processGO:00436321330.144
protein localization to organelleGO:00333651850.142
regulation of protein localizationGO:00328802310.141
nucleoside triphosphate metabolic processGO:00091412300.133
purine containing compound catabolic processGO:00725232130.132
organophosphate catabolic processGO:00464342320.131
nucleoside catabolic processGO:00091642060.127
regulation of protein catabolic processGO:00421761080.121
ribonucleotide metabolic processGO:00092592910.119
nucleoside phosphate catabolic processGO:19012922220.115
aromatic compound catabolic processGO:00194392860.110
purine ribonucleoside triphosphate metabolic processGO:00092052200.109
ribonucleoside metabolic processGO:00091192450.105
purine ribonucleoside triphosphate catabolic processGO:00092071990.103
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.101
dna metabolic processGO:00062593030.100
dna repairGO:00062811070.100
nucleoside metabolic processGO:00091162460.099
purine nucleoside catabolic processGO:00061522050.094
organic cyclic compound catabolic processGO:19013612950.092
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.091
regulation of intracellular protein transportGO:0033157820.082
trna processingGO:0008033110.081
regulation of cellular catabolic processGO:00313292420.079
cellular nitrogen compound catabolic processGO:00442702800.079
maintenance of locationGO:0051235890.078
negative regulation of cell cycleGO:00457861230.075
negative regulation of mitotic cell cycleGO:0045930580.072
mitotic cell cycle processGO:19030471590.071
ribose phosphate metabolic processGO:00196932910.071
translational initiationGO:0006413240.068
positive regulation of cell deathGO:00109422240.068
organelle fissionGO:00482851700.067
establishment of organelle localizationGO:00516561220.067
ras protein signal transductionGO:0007265770.066
regulation of transcription factor import into nucleusGO:0042990240.066
organelle assemblyGO:00709251770.065
ribonucleoside triphosphate metabolic processGO:00091992200.064
development of primary sexual characteristicsGO:00451371430.064
atp catabolic processGO:0006200550.061
positive regulation of apoptotic processGO:00430652170.060
organelle localizationGO:00516401790.059
positive regulation of cellular protein catabolic processGO:1903364340.059
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.058
negative regulation of protein metabolic processGO:00512482820.058
protein importGO:00170381010.057
nucleoside phosphate metabolic processGO:00067533380.056
mitotic g2 dna damage checkpointGO:000709580.053
purine nucleotide metabolic processGO:00061633020.051
regulation of protein transportGO:00512231630.050
positive regulation of protein catabolic processGO:0045732600.050
stem cell differentiationGO:00488632680.050
regulation of cell cycle phase transitionGO:1901987770.049
regulation of cell migrationGO:00303342190.049
positive regulation of programmed cell deathGO:00430682180.048
regulation of cytoplasmic transportGO:19036491120.047
protein digestionGO:004425610.047
nucleoside triphosphate catabolic processGO:00091432050.046
cytoplasmic transportGO:00164822340.046
neuron migrationGO:00017641220.045
regulation of establishment of protein localizationGO:00702011810.045
regulation of protein targetingGO:1903533610.045
ribonucleoside monophosphate metabolic processGO:0009161800.045
guanosine containing compound catabolic processGO:19010691440.045
stem cell maintenanceGO:00198271300.045
trna wobble base modificationGO:000209720.044
protein modification by small protein conjugationGO:00324461870.043
gtp metabolic processGO:00460391440.043
dna integrity checkpointGO:0031570280.043
negative regulation of cell proliferationGO:00082852960.042
intracellular protein transportGO:00068862040.042
purine containing compound metabolic processGO:00725213110.041
positive regulation of transferase activityGO:00513471670.039
heterocycle catabolic processGO:00467002800.038
positive regulation of proteolysisGO:0045862850.038
protein foldingGO:0006457280.038
purine nucleoside metabolic processGO:00422782410.037
positive regulation of ras gtpase activityGO:0032320650.037
muscle tissue developmentGO:00605373080.036
lateral inhibitionGO:004633110.035
protein dna complex subunit organizationGO:0071824280.035
positive regulation of cell cycleGO:0045787920.035
retrograde transport endosome to golgiGO:004214720.033
purine ribonucleoside monophosphate metabolic processGO:0009167800.033
regulation of protein complex assemblyGO:0043254830.030
response to inorganic substanceGO:0010035960.030
developmental maturationGO:00217001930.030
positive regulation of cell cycle processGO:0090068610.030
negative regulation of protein modification processGO:00314001630.030
cellular ketone metabolic processGO:0042180840.030
regulation of proteolysisGO:00301621640.029
purine nucleoside triphosphate metabolic processGO:00091442260.029
regulation of cell divisionGO:0051302760.029
regulation of protein kinase activityGO:00458592320.029
cell divisionGO:00513011200.028
Worm
membrane fusionGO:0061025380.028
negative regulation of cellular protein metabolic processGO:00322692470.028
negative regulation of cell cycle phase transitionGO:1901988480.028
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.028
striated muscle cell developmentGO:00550021250.028
endocytosisGO:00068971680.028
cellular amine metabolic processGO:0044106440.027
response to organonitrogen compoundGO:00102432460.026
protein modification by small protein removalGO:0070646210.026
Human
purine nucleoside triphosphate catabolic processGO:00091462030.026
regulation of protein processingGO:0070613960.026
regulation of cellular protein catabolic processGO:1903362610.025
negative regulation of mitotic cell cycle phase transitionGO:1901991450.025
nucleobase containing small molecule metabolic processGO:00550863520.025
negative regulation of intracellular signal transductionGO:19025321670.025
chromatin modificationGO:00165681870.025
response to organic cyclic compoundGO:00140701980.024
positive regulation of nucleotide catabolic processGO:0030813880.024
cellular response to organonitrogen compoundGO:00714171450.024
positive regulation of hydrolase activityGO:00513451480.024
regulation of kinase activityGO:00435492490.023
positive regulation of mitotic cell cycleGO:0045931410.023
regulation of cellular component sizeGO:00325351210.023
stem cell developmentGO:00488642190.023
gene silencingGO:0016458380.022
regulation of ras gtpase activityGO:0032318880.022
negative regulation of insulin receptor signaling pathwayGO:0046627140.022
regulation of mapk cascadeGO:00434082480.022
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:0031146100.021
ossificationGO:00015032160.021
centrosome duplicationGO:0051298160.021
cell cycle g1 s phase transitionGO:0044843570.021
muscle cell differentiationGO:00426922610.021
dna dependent dna replicationGO:0006261240.021
mitotic nuclear divisionGO:0007067480.021
amp metabolic processGO:004603340.021
nuclear importGO:0051170950.021
positive regulation of intracellular protein transportGO:0090316420.021
amine metabolic processGO:0009308450.021
negative regulation of cell cycle processGO:0010948690.020
dna damage checkpointGO:0000077260.020
meiotic cell cycle processGO:1903046770.020
cell maturationGO:00484691270.020
dna replicationGO:0006260520.020
cellular amino acid metabolic processGO:00065201030.019
regionalizationGO:00030023370.019
regulation of apoptotic signaling pathwayGO:20012331970.019
microtubule based processGO:00070172360.019
regulation of cellular response to stressGO:00801351590.019
immune effector processGO:00022523210.019
regulation of intracellular transportGO:00323861590.018
positive regulation of cell cycle phase transitionGO:1901989170.018
purine ribonucleoside monophosphate catabolic processGO:0009169570.018
lipid localizationGO:00108761260.018
regulation of nucleotide metabolic processGO:00061401690.018
developmental growth involved in morphogenesisGO:00605601380.018
ribosomal small subunit biogenesisGO:004227440.018
positive regulation of mitotic cell cycle phase transitionGO:1901992170.018
multicellular organismal macromolecule catabolic processGO:004426610.018
nfat protein import into nucleusGO:005153160.018
chromatin organizationGO:00063252060.017
protein oligomerizationGO:0051259670.017
neuronal action potentialGO:0019228540.017
trna metabolic processGO:0006399110.017
g2 dna damage checkpointGO:003157280.017
regulation of cell adhesionGO:00301551540.017
cellularizationGO:000734910.017
regulation of transferase activityGO:00513382630.017
nucleoside monophosphate metabolic processGO:0009123850.017
purine nucleoside monophosphate metabolic processGO:0009126810.017
regulation of system processGO:00440572000.016
body morphogenesisGO:0010171450.016
atp metabolic processGO:0046034750.016
negative regulation of molecular functionGO:00440922580.016
regulation of organelle organizationGO:00330432890.016
negative regulation of cellular component organizationGO:00511291940.016
positive regulation of apoptotic signaling pathwayGO:2001235950.015
purine nucleoside monophosphate catabolic processGO:0009128580.015
positive regulation of protein kinase activityGO:00458601440.015
insulin receptor signaling pathwayGO:0008286490.015
response to uvGO:0009411440.015
lung field specificationGO:006042430.015
regulation of cellular response to growth factor stimulusGO:0090287820.015
regulation of nucleocytoplasmic transportGO:0046822730.015
regulation of peptidyl tyrosine phosphorylationGO:0050730930.014
mitotic cell cycle checkpointGO:0007093310.014
negative regulation of tor signalingGO:0032007130.014
gtp catabolic processGO:00061841430.014
genitalia developmentGO:0048806370.014
muscle cell developmentGO:00550011330.014
protein ubiquitinationGO:00165671710.014
negative regulation of immune system processGO:00026832090.014
positive regulation of nfat protein import into nucleusGO:005153310.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
protein import into nucleusGO:0006606950.014
posttranscriptional regulation of gene expressionGO:00106081550.013
positive regulation of cell adhesionGO:0045785800.013
striated muscle tissue developmentGO:00147062930.013
nucleoside monophosphate catabolic processGO:0009125590.013
regulation of hydrolase activityGO:00513362460.013
er associated ubiquitin dependent protein catabolic processGO:0030433100.013
mitotic sister chromatid segregationGO:0000070140.013
tor signalingGO:0031929210.013
negative regulation of protein phosphorylationGO:00019331260.013
rna interferenceGO:001624620.013
male gamete generationGO:00482322850.013
positive regulation of protein autophosphorylationGO:003195440.013
regulation of epithelial cell proliferationGO:00506781410.013
segmentationGO:0035282930.012
positive regulation of dna templated transcription elongationGO:003278620.012
positive regulation of cell migrationGO:00303351090.012
cardiocyte differentiationGO:0035051870.012
regulation of anatomical structure sizeGO:00900661780.012
regulation of jnk cascadeGO:0046328620.012
positive regulation of dna templated transcription initiationGO:200014450.012
protein deubiquitinationGO:0016579190.012
regulation of protein import into nucleusGO:0042306520.012
neuron maturationGO:0042551290.012
forebrain developmentGO:00309003020.012
circulatory system processGO:00030131970.012
regulation of cell motilityGO:20001452360.012
regulation of ras protein signal transductionGO:00465781140.012
regulation of vesicle mediated transportGO:00606271390.012
cytokinesisGO:0000910170.012
Worm
negative regulation of cellular response to insulin stimulusGO:1900077160.011
transforming growth factor beta2 productionGO:003290620.011
establishment of spindle localizationGO:0051293190.011
positive regulation of protein complex assemblyGO:0031334450.011
cell adhesionGO:00071553290.011
wnt signaling pathwayGO:00160551880.011
cellular response to peptide hormone stimulusGO:0071375920.011
maintenance of location in cellGO:0051651240.011
meiotic cell cycleGO:00513211220.011
regulation of cellular ketone metabolic processGO:0010565660.011
telencephalon developmentGO:00215371860.011
attachment of spindle microtubules to kinetochoreGO:000860840.011
amp biosynthetic processGO:000616720.011
establishment of protein localization to endoplasmic reticulumGO:007259920.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
blastocyst developmentGO:0001824800.011
regulation of vacuole organizationGO:004408840.011
spindle organizationGO:0007051280.011
endoplasmic reticulum tubular network organizationGO:007178610.010
regulation of microtubule based processGO:0032886520.010
positive regulation of phospholipase activityGO:001051830.010
spermatid developmentGO:00072861080.010
regulation of nucleotide catabolic processGO:00308111220.010
single organism nuclear importGO:1902593950.010
negative regulation of protein processingGO:0010955790.010
g1 s transition of mitotic cell cycleGO:0000082570.010
protein maturationGO:00516041760.010
response to transforming growth factor betaGO:0071559880.010

Cops2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye and adnexa diseaseDOID:149200.071
eye diseaseDOID:561400.071
sensory system diseaseDOID:005015500.071
disease of anatomical entityDOID:700.071
retinal diseaseDOID:567900.071
retinal degenerationDOID:846600.071
nervous system diseaseDOID:86300.071
central nervous system diseaseDOID:33100.017
neurodegenerative diseaseDOID:128900.017