Mus musculus

9 known processes

Cops5

COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)

(Aliases: Jab1,CSN5,Mov34,AI303502,Sgn5)

Cops5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein removalGO:0070646211.000
Human Worm Fly
proteolysis involved in cellular protein catabolic processGO:00516031470.744
Fly
modification dependent protein catabolic processGO:00199411330.709
Fly
modification dependent macromolecule catabolic processGO:00436321330.693
Fly
protein modification by small protein conjugation or removalGO:00706472070.660
Human Worm Fly
protein catabolic processGO:00301632210.641
Fly
cellular protein catabolic processGO:00442571550.543
Fly
cellular response to dna damage stimulusGO:00069742070.531
Fly
proteasomal protein catabolic processGO:0010498980.530
Fly
macromolecule catabolic processGO:00090572810.470
Fly
ubiquitin dependent protein catabolic processGO:00065111290.425
Fly
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.240
Fly
lateral inhibitionGO:004633110.230
proteasomal ubiquitin independent protein catabolic processGO:001049910.211
cellular macromolecule catabolic processGO:00442652060.186
Fly
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.154
nucleotide metabolic processGO:00091173320.154
regulation of cell cycleGO:00517262810.153
purine ribonucleotide metabolic processGO:00091502900.150
negative regulation of protein metabolic processGO:00512482820.136
Fly
positive regulation of protein catabolic processGO:0045732600.123
Fly
purine ribonucleoside metabolic processGO:00461282410.118
regulation of cellular protein catabolic processGO:1903362610.115
Fly
microtubule cytoskeleton organization involved in mitosisGO:190285040.114
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.104
Fly
spermatid differentiationGO:00485151150.103
purine nucleotide catabolic processGO:00061952110.102
organelle assemblyGO:00709251770.097
positive regulation of cellular component biogenesisGO:0044089940.091
male gamete generationGO:00482322850.089
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.089
Fly
mitotic cell cycleGO:00002781950.088
Fly
regulation of proteolysisGO:00301621640.086
Fly
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.085
cellular nitrogen compound catabolic processGO:00442702800.084
nucleotide catabolic processGO:00091662170.082
aromatic compound catabolic processGO:00194392860.079
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.077
Fly
positive regulation of protein modification processGO:00314012990.077
spindle assembly involved in mitosisGO:009030740.072
carbohydrate derivative catabolic processGO:19011362310.072
nucleobase containing small molecule metabolic processGO:00550863520.071
ribonucleoside triphosphate metabolic processGO:00091992200.067
protein maturationGO:00516041760.067
Fly
nucleoside phosphate metabolic processGO:00067533380.066
organelle fissionGO:00482851700.063
purine ribonucleoside triphosphate catabolic processGO:00092071990.061
proteasome assemblyGO:004324810.061
regulation of mitotic cell cycleGO:00073461260.061
Fly
regulation of cellular component biogenesisGO:00440871810.059
guanosine containing compound metabolic processGO:19010681440.059
chromatin modificationGO:00165681870.058
ribonucleoside metabolic processGO:00091192450.058
regulation of cell cycle processGO:00105641600.058
Fly
purine containing compound metabolic processGO:00725213110.057
regulation of protein maturationGO:1903317960.056
Fly
intracellular protein transportGO:00068862040.056
mitotic cell cycle processGO:19030471590.055
Fly
heterocycle catabolic processGO:00467002800.053
purine nucleotide metabolic processGO:00061633020.052
chromatin organizationGO:00063252060.051
histone modificationGO:00165701590.050
cell fate commitmentGO:00451652100.047
organophosphate catabolic processGO:00464342320.047
regulation of protein processingGO:0070613960.046
Fly
purine ribonucleoside catabolic processGO:00461302050.046
negative regulation of cell cycleGO:00457861230.045
Fly
spermatid developmentGO:00072861080.045
positive regulation of hydrolase activityGO:00513451480.044
ribonucleoside triphosphate catabolic processGO:00092031990.043
regulation of protein catabolic processGO:00421761080.043
Fly
nuclear divisionGO:00002801580.043
ribose phosphate metabolic processGO:00196932910.042
nucleoside metabolic processGO:00091162460.042
regulation of chromosome organizationGO:0033044830.041
negative regulation of proteolysisGO:0045861740.040
Fly
organonitrogen compound catabolic processGO:19015652640.040
atp metabolic processGO:0046034750.039
negative regulation of protein processingGO:0010955790.039
Fly
purine nucleoside catabolic processGO:00061522050.038
positive regulation of protein complex assemblyGO:0031334450.038
protein localization to organelleGO:00333651850.038
microtubule cytoskeleton organizationGO:00002261570.038
covalent chromatin modificationGO:00165691630.037
posttranscriptional regulation of gene expressionGO:00106081550.037
Fly
nucleoside phosphate catabolic processGO:19012922220.037
cytoplasmic transportGO:00164822340.036
protein targetingGO:00066051430.036
ribonucleotide catabolic processGO:00092612080.035
cell divisionGO:00513011200.035
Worm
ribonucleoside monophosphate metabolic processGO:0009161800.034
protein importGO:00170381010.034
positive regulation of cellular protein catabolic processGO:1903364340.034
Fly
mitotic cytokinesisGO:000028140.033
regulation of hydrolase activityGO:00513362460.033
purine ribonucleotide catabolic processGO:00091542080.033
negative regulation of cell proliferationGO:00082852960.033
Fly
purine ribonucleoside triphosphate metabolic processGO:00092052200.032
purine nucleoside triphosphate catabolic processGO:00091462030.032
protein stabilizationGO:0050821250.031
Fly
ribonucleotide metabolic processGO:00092592910.031
dna recombinationGO:0006310920.031
protein processingGO:00164851630.030
Fly
nucleoside triphosphate catabolic processGO:00091432050.030
negative regulation of protein maturationGO:1903318790.030
Fly
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.030
Fly
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.030
spermatogenesisGO:00072832840.029
regulation of proteasomal protein catabolic processGO:0061136460.029
Fly
positive regulation of kinase activityGO:00336741550.029
purine containing compound catabolic processGO:00725232130.029
regulation of cellular catabolic processGO:00313292420.028
Fly
nuclear importGO:0051170950.028
dna metabolic processGO:00062593030.028
regulation of transferase activityGO:00513382630.028
negative regulation of cellular component organizationGO:00511291940.028
double strand break repair via homologous recombinationGO:0000724210.027
cellular protein complex assemblyGO:00436231160.027
double strand break repairGO:0006302480.027
positive regulation of cellular amine metabolic processGO:003324050.027
negative regulation of cell developmentGO:00107211690.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
regulation of protein complex assemblyGO:0043254830.026
organic cyclic compound catabolic processGO:19013612950.026
regulation of vesicle mediated transportGO:00606271390.026
negative regulation of cellular protein metabolic processGO:00322692470.026
Fly
positive regulation of protein serine threonine kinase activityGO:00719021060.025
regulation of cellular amine metabolic processGO:0033238200.025
camera type eye developmentGO:00430102660.025
protein acylationGO:0043543640.025
er to golgi vesicle mediated transportGO:0006888110.024
glycosyl compound catabolic processGO:19016582060.024
internal protein amino acid acetylationGO:0006475420.024
amine metabolic processGO:0009308450.024
microtubule based processGO:00070172360.023
single fertilizationGO:0007338820.023
positive regulation of transferase activityGO:00513471670.022
membrane organizationGO:00610242450.022
protein deubiquitinationGO:0016579190.022
Human
sperm individualizationGO:000729110.022
peptidyl amino acid modificationGO:00181933360.022
neural tube formationGO:00018411080.022
actin cytoskeleton organizationGO:00300362200.022
glycosyl compound metabolic processGO:19016572460.022
maintenance of locationGO:0051235890.022
developmental maturationGO:00217001930.021
Fly
purine ribonucleoside monophosphate metabolic processGO:0009167800.021
regulation of cytoplasmic transportGO:19036491120.021
regulation of organelle organizationGO:00330432890.021
establishment of protein localization to organelleGO:00725941180.021
ribonucleoside catabolic processGO:00424542060.021
gonad developmentGO:00084061410.020
Worm
recombinational repairGO:0000725210.020
regulation of multi organism processGO:00439001110.020
nucleoside triphosphate metabolic processGO:00091412300.019
oocyte anterior posterior axis specificationGO:000731420.019
Fly
negative regulation of immune system processGO:00026832090.019
Fly
purine nucleoside triphosphate metabolic processGO:00091442260.019
transmembrane transportGO:00550854120.019
cytokinesisGO:0000910170.019
Worm
regulation of cell cycle phase transitionGO:1901987770.019
Fly
gtp catabolic processGO:00061841430.019
cell cell signaling involved in cell fate commitmentGO:0045168350.019
dna integrity checkpointGO:0031570280.018
Fly
germ cell developmentGO:00072811850.018
Worm Fly
positive regulation of dna templated transcription elongationGO:003278620.018
regulation of histone modificationGO:0031056560.018
regulation of protein ubiquitinationGO:0031396520.018
positive regulation of protein kinase activityGO:00458601440.018
organelle localizationGO:00516401790.018
regulation of intracellular transportGO:00323861590.018
regulation of protein stabilityGO:0031647520.018
Fly
cell cycle checkpointGO:0000075470.018
Fly
nucleoside monophosphate metabolic processGO:0009123850.018
ossificationGO:00015032160.018
protein import into nucleusGO:0006606950.018
negative regulation of protein catabolic processGO:0042177360.018
Fly
development of primary sexual characteristicsGO:00451371430.017
Worm
regulation of cellular amino acid metabolic processGO:000652150.017
golgi vesicle transportGO:0048193300.017
regulation of ion transportGO:00432692150.017
nucleoside catabolic processGO:00091642060.017
regulation of mitotic cell cycle phase transitionGO:1901990730.017
Fly
protein localization to nucleusGO:00345041210.017
leukocyte proliferationGO:00706611720.017
small gtpase mediated signal transductionGO:0007264970.017
negative regulation of cell cycle processGO:0010948690.017
Fly
single organism nuclear importGO:1902593950.017
regulation of establishment of protein localizationGO:00702011810.016
regulation of protein serine threonine kinase activityGO:00719001570.016
purine nucleoside metabolic processGO:00422782410.016
fertilizationGO:00095661270.016
regulation of peptidase activityGO:0052547960.016
guanosine containing compound catabolic processGO:19010691440.016
stem cell differentiationGO:00488632680.016
striated muscle tissue developmentGO:00147062930.016
regulation of kinase activityGO:00435492490.016
protein neddylationGO:004511610.016
cellular amine metabolic processGO:0044106440.015
negative regulation of phosphate metabolic processGO:00459361840.015
positive regulation of cellular catabolic processGO:00313311480.015
Fly
regulation of protein localization to nucleusGO:1900180600.015
negative regulation of cellular protein catabolic processGO:1903363220.015
Fly
negative regulation of molecular functionGO:00440922580.015
spindle organizationGO:0007051280.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
regulation of cytoskeleton organizationGO:00514931220.015
protein modification by small protein conjugationGO:00324461870.015
regulation of protein localizationGO:00328802310.015
peptidyl lysine acetylationGO:0018394450.015
histone acetylationGO:0016573410.014
regulation of protein targetingGO:1903533610.014
t cell proliferationGO:00420981200.014
response to organonitrogen compoundGO:00102432460.014
stem cell developmentGO:00488642190.014
regulation of protein kinase activityGO:00458592320.014
er associated ubiquitin dependent protein catabolic processGO:0030433100.014
positive regulation of proteolysisGO:0045862850.014
Fly
organic hydroxy compound metabolic processGO:19016152030.014
extracellular structure organizationGO:00430621480.014
intracellular mrna localizationGO:000829840.014
positive regulation of cell deathGO:00109422240.013
positive regulation of organelle organizationGO:00106381280.013
positive regulation of peptidase activityGO:0010952490.013
regulation of cellular ketone metabolic processGO:0010565660.013
dna templated transcriptional preinitiation complex assemblyGO:007089740.013
chromosome segregationGO:0007059480.013
forebrain developmentGO:00309003020.013
regulation of cell migrationGO:00303342190.013
regulation of hormone levelsGO:00108172110.013
methylationGO:00322591340.013
nuclear transportGO:00511691390.013
regulation of cell growthGO:0001558910.012
mitotic cell cycle checkpointGO:0007093310.012
Fly
transforming growth factor beta receptor signaling pathwayGO:0007179710.012
protein polymerizationGO:0051258570.012
regulation of membrane potentialGO:00423911920.012
regulation of translationGO:0006417710.012
negative regulation of mitotic cell cycleGO:0045930580.012
Fly
cell maturationGO:00484691270.012
Fly
peptidyl lysine modificationGO:0018205770.012
blood circulationGO:00080151950.011
nitrogen compound transportGO:00717052710.011
transcription initiation from rna polymerase ii promoterGO:000636780.011
regulation of ion transmembrane transportGO:00347651190.011
sensory organ morphogenesisGO:00905962420.011
Fly
cellular amino acid metabolic processGO:00065201030.011
dna repairGO:00062811070.011
positive regulation of chromosome organizationGO:2001252330.011
negative regulation of mitotic cell cycle phase transitionGO:1901991450.011
Fly
circulatory system processGO:00030131970.011
tube formationGO:00351481400.011
apoptotic signaling pathwayGO:00971903060.011
ion transmembrane transportGO:00342203610.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
mitotic g2 dna damage checkpointGO:000709580.011
Fly
regulation of secretionGO:00510462740.011
inflammatory responseGO:00069542440.011
epithelial cell proliferationGO:00506731740.011
leukocyte migrationGO:00509001240.011
blastocyst developmentGO:0001824800.011
regulation of system processGO:00440572000.011
positive regulation of cell cycleGO:0045787920.011
Fly
sperm egg recognitionGO:0035036370.010
negative regulation of phosphorylationGO:00423261660.010
digestive system developmentGO:00551232000.010
rna splicing via endonucleolytic cleavage and ligationGO:000039410.010
muscle tissue developmentGO:00605373080.010
locomotory behaviorGO:00076261950.010
epithelial tube morphogenesisGO:00605623030.010
response to organic cyclic compoundGO:00140701980.010

Cops5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.010