IMP: Integrative Multi-species Prediction

Mus musculus

136 known processes

Tnfsf14

tumor necrosis factor (ligand) superfamily, member 14

(Aliases: HVEML,Ly113,LTg,HVEM-L,LIGHT)

Entrez: 50930
Ensembl: ENSMUSG00000005824
UniProtKB: Q9QYH9

Process Predictions
Disease Predictions

Tnfsf14 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of translational initiation	GO:0045948	4	0.990	Mouse
positive regulation of chronic inflammatory response	GO:0002678	4	0.937	Mouse
regulation of translational initiation by iron	GO:0006447	2	0.915	Mouse
positive regulation of translational initiation by iron	GO:0045994	2	0.866	Mouse
lymph node development	GO:0048535	18	0.844	Mouse
regulation of b cell proliferation	GO:0030888	39	0.842
positive regulation of cell activation	GO:0050867	158	0.834
positive regulation of leukocyte proliferation	GO:0070665	73	0.827
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.817
metal ion homeostasis	GO:0055065	189	0.812	Mouse
positive regulation of cd8 positive alpha beta t cell extravasation	GO:2000451	2	0.805
positive regulation of monocyte chemotaxis	GO:0090026	2	0.749
regulation of cytokine production	GO:0001817	266	0.711	Mouse
positive regulation of osteoclast development	GO:2001206	3	0.708	Mouse
engulfment of apoptotic cell	GO:0043652	3	0.705	Fly
skeletal muscle fiber development	GO:0048741	58	0.700
regulation of lymphocyte chemotaxis	GO:1901623	6	0.691
necroptotic signaling pathway	GO:0097527	3	0.675	Mouse
extrinsic apoptotic signaling pathway	GO:0097191	126	0.674	Mouse Fly
chronic inflammatory response to antigenic stimulus	GO:0002439	3	0.671	Mouse
corticotropin releasing hormone secretion	GO:0043396	2	0.648	Mouse
lymphocyte migration	GO:0072676	26	0.647
regulation of cell activation	GO:0050865	289	0.636
positive regulation of inflammatory response to antigenic stimulus	GO:0002863	11	0.628	Mouse
positive regulation of interleukin 12 production	GO:0032735	21	0.611
cell fate commitment	GO:0045165	210	0.605	Fly
t cell activation	GO:0042110	289	0.594
t cell migration	GO:0072678	19	0.580
t cell chemotaxis	GO:0010818	6	0.575
positive regulation of b cell activation	GO:0050871	49	0.568
positive regulation of cell motility	GO:2000147	116	0.567
positive regulation of chronic inflammatory response to antigenic stimulus	GO:0002876	2	0.563	Mouse
positive regulation of fever generation by positive regulation of prostaglandin secretion	GO:0071812	2	0.558	Mouse
extrinsic apoptotic signaling pathway in absence of ligand	GO:0097192	55	0.556
myeloid cell differentiation	GO:0030099	233	0.526	Mouse
interleukin 1 secretion	GO:0050701	16	0.511
negative regulation of ossification	GO:0030279	49	0.510	Mouse
positive regulation of b cell proliferation	GO:0030890	24	0.506
regulation of interleukin 6 production	GO:0032675	55	0.505	Mouse
cd8 positive alpha beta t cell extravasation	GO:0035697	3	0.505
regulation of b cell activation	GO:0050864	81	0.491
regulation of acute inflammatory response	GO:0002673	27	0.486	Mouse
positive regulation of chemotaxis	GO:0050921	38	0.482
positive regulation of osteoclast differentiation	GO:0045672	15	0.480	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.478	Mouse
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.478
prostaglandin transport	GO:0015732	7	0.475	Mouse
guanosine containing compound metabolic process	GO:1901068	144	0.472
t cell extravasation	GO:0072683	4	0.466
positive regulation of cell development	GO:0010720	237	0.465	Mouse
somatic diversification of immune receptors via germline recombination within a single locus	GO:0002562	51	0.463	Mouse
positive regulation of cytokine biosynthetic process	GO:0042108	40	0.457
positive regulation of interferon gamma production	GO:0032729	39	0.443	Mouse
regulation of chronic inflammatory response to antigenic stimulus	GO:0002874	3	0.433	Mouse
regulation of leukocyte proliferation	GO:0070663	121	0.433
leukocyte differentiation	GO:0002521	342	0.424	Mouse
single organism cell adhesion	GO:0098602	156	0.419
regulation of lymphocyte migration	GO:2000401	14	0.410
interleukin 12 secretion	GO:0072610	3	0.407
lymphocyte chemotaxis	GO:0048247	10	0.406
inflammatory response	GO:0006954	244	0.403	Mouse
positive regulation of cellular catabolic process	GO:0031331	148	0.400
positive regulation of icosanoid secretion	GO:0032305	7	0.399	Mouse
defense response to gram positive bacterium	GO:0050830	50	0.391	Mouse
cytokine production	GO:0001816	319	0.391	Mouse
cytoplasmic transport	GO:0016482	234	0.389	Mouse
axon ensheathment	GO:0008366	76	0.381
eosinophil degranulation	GO:0043308	1	0.377
eosinophil activation involved in immune response	GO:0002278	1	0.370
morphogenesis of a branching structure	GO:0001763	203	0.366	Mouse
ras protein signal transduction	GO:0007265	77	0.365
b cell differentiation	GO:0030183	78	0.364	Mouse
cellular calcium ion homeostasis	GO:0006874	119	0.361
osteoclast development	GO:0036035	9	0.358	Mouse
regulation of cell migration	GO:0030334	219	0.358
positive regulation of myoblast differentiation	GO:0045663	8	0.357
mature dendritic cell differentiation	GO:0097029	3	0.351
t cell differentiation in thymus	GO:0033077	77	0.348
dephosphorylation	GO:0016311	129	0.346	Mouse
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.342
apoptotic signaling pathway	GO:0097190	306	0.341	Mouse Fly
positive regulation of ion transport	GO:0043270	65	0.339	Mouse
regulation of establishment of protein localization	GO:0070201	181	0.336	Mouse
negative regulation of osteoblast differentiation	GO:0045668	30	0.333	Mouse
positive regulation of t cell activation	GO:0050870	101	0.332
chemotaxis	GO:0006935	247	0.331
positive regulation of lymphocyte proliferation	GO:0050671	70	0.328
cellular ion homeostasis	GO:0006873	165	0.323
positive regulation of defense response	GO:0031349	124	0.323	Mouse
regulation of lymphocyte differentiation	GO:0045619	107	0.317
positive regulation of gliogenesis	GO:0014015	27	0.316
lymphocyte proliferation	GO:0046651	164	0.315
b cell activation	GO:0042113	161	0.313	Mouse
positive regulation of lymphocyte activation	GO:0051251	140	0.308
ensheathment of neurons	GO:0007272	76	0.301
immune complex clearance	GO:0002434	2	0.300
negative regulation of myoblast differentiation	GO:0045662	18	0.300	Mouse
cell chemotaxis	GO:0060326	81	0.297
integrin activation	GO:0033622	8	0.291
positive regulation of cell cycle process	GO:0090068	61	0.289
regulation of translational initiation	GO:0006446	15	0.289	Mouse
negative regulation of growth of symbiont in host	GO:0044130	19	0.288	Mouse
positive regulation of humoral immune response mediated by circulating immunoglobulin	GO:0002925	6	0.288	Mouse
response to tumor necrosis factor	GO:0034612	26	0.287	Mouse
regulation of monocyte extravasation	GO:2000437	2	0.286
positive regulation of peptide secretion	GO:0002793	33	0.282	Mouse
negative regulation of glucose transport	GO:0010829	9	0.281	Mouse
positive regulation of oligodendrocyte differentiation	GO:0048714	9	0.278
positive regulation of fever generation	GO:0031622	6	0.278	Mouse
stress activated protein kinase signaling cascade	GO:0031098	81	0.278	Mouse Fly
t cell receptor signaling pathway	GO:0050852	46	0.276
alpha beta t cell proliferation	GO:0046633	21	0.275
glucose transport	GO:0015758	56	0.273	Mouse
positive regulation of heat generation	GO:0031652	7	0.273	Mouse
gland development	GO:0048732	330	0.271	Mouse
humoral immune response	GO:0006959	57	0.270	Mouse
regulation of jnk cascade	GO:0046328	62	0.270	Mouse
regulation of cytokine secretion	GO:0050707	61	0.267
pallium development	GO:0021543	120	0.266
regulation of monocyte chemotaxis	GO:0090025	3	0.265
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001240	16	0.264
regulation of leukocyte mediated immunity	GO:0002703	104	0.263	Mouse
regulation of hydrolase activity	GO:0051336	246	0.261	Mouse
telencephalon development	GO:0021537	186	0.261
fever generation	GO:0001660	7	0.259	Mouse
jnk cascade	GO:0007254	72	0.258	Mouse Fly
positive regulation of hydrolase activity	GO:0051345	148	0.257	Mouse
positive regulation of corticotropin releasing hormone secretion	GO:0051466	1	0.253	Mouse
osteoclast proliferation	GO:0002158	4	0.253	Mouse
negative regulation of molecular function	GO:0044092	258	0.253	Mouse
cellular response to lipopolysaccharide	GO:0071222	77	0.252	Mouse
regulation of cell motility	GO:2000145	236	0.251
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.246	Mouse
bone resorption	GO:0045453	38	0.245	Mouse
oligodendrocyte differentiation	GO:0048709	53	0.245
regulation of integrin activation	GO:0033623	4	0.243
gliogenesis	GO:0042063	141	0.241
positive regulation of muscle cell differentiation	GO:0051149	39	0.235
positive regulation of cell migration	GO:0030335	109	0.233
calcium ion transport	GO:0006816	159	0.233
positive regulation of behavior	GO:0048520	40	0.233
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.233
tissue remodeling	GO:0048771	102	0.232	Mouse
myeloid leukocyte activation	GO:0002274	83	0.230
interleukin 12 production	GO:0032615	32	0.228
calcium ion homeostasis	GO:0055074	127	0.225	Mouse
cytosolic calcium ion homeostasis	GO:0051480	70	0.224
regulation of lymphocyte activation	GO:0051249	240	0.223
positive regulation of monocyte extravasation	GO:2000439	1	0.222
nucleoside phosphate catabolic process	GO:1901292	222	0.222
cellular response to fibroblast growth factor stimulus	GO:0044344	47	0.221
regulation of cell cycle process	GO:0010564	160	0.219
cytokine biosynthetic process	GO:0042089	68	0.219
myeloid cell activation involved in immune response	GO:0002275	34	0.216
negative regulation of muscle cell differentiation	GO:0051148	33	0.216	Mouse
positive regulation of cysteine type endopeptidase activity	GO:2001056	39	0.212	Mouse
regulation of protein serine threonine kinase activity	GO:0071900	157	0.211	Mouse
positive regulation of t cell differentiation	GO:0045582	52	0.210
regulation of t cell costimulation	GO:2000523	2	0.210
translational initiation	GO:0006413	24	0.210	Mouse
positive regulation of cytokine production	GO:0001819	174	0.208	Mouse
divalent metal ion transport	GO:0070838	172	0.207
positive regulation of organic acid transport	GO:0032892	11	0.206	Mouse
response to fibroblast growth factor	GO:0071774	47	0.205
mapk cascade	GO:0000165	281	0.205	Mouse Fly
regulation of defense response	GO:0031347	233	0.205	Mouse
branching involved in salivary gland morphogenesis	GO:0060445	26	0.205	Mouse
b cell chemotaxis	GO:0035754	3	0.204
gtp metabolic process	GO:0046039	144	0.204
membrane organization	GO:0061024	245	0.203	Fly
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.203
regulation of homeostatic process	GO:0032844	182	0.202	Mouse
negative regulation of exocytosis	GO:0045920	12	0.202
regulation of dendritic cell chemotaxis	GO:2000508	1	0.202
eosinophil activation	GO:0043307	1	0.201
positive regulation of nucleotide catabolic process	GO:0030813	88	0.201
eosinophil mediated immunity	GO:0002447	1	0.200
regulation of humoral immune response	GO:0002920	22	0.199	Mouse
regulation of organ morphogenesis	GO:2000027	144	0.197	Mouse
gtp catabolic process	GO:0006184	143	0.195
i kappab kinase nf kappab signaling	GO:0007249	85	0.193	Mouse
inflammatory response to antigenic stimulus	GO:0002437	30	0.193	Mouse
regulation of interleukin 12 production	GO:0032655	30	0.192
positive regulation of nervous system development	GO:0051962	221	0.191
microglial cell activation involved in immune response	GO:0002282	1	0.191
b cell activation involved in immune response	GO:0002312	50	0.190	Mouse
hexose metabolic process	GO:0019318	98	0.188	Mouse
odontogenesis	GO:0042476	78	0.188
positive regulation of cell death	GO:0010942	224	0.186	Mouse
epithelial tube morphogenesis	GO:0060562	303	0.186
regulation of vasculature development	GO:1901342	88	0.184
interspecies interaction between organisms	GO:0044419	83	0.184	Mouse
transmission of nerve impulse	GO:0019226	76	0.183
activation of cysteine type endopeptidase activity	GO:0097202	27	0.182	Mouse
organonitrogen compound catabolic process	GO:1901565	264	0.178
regulation of oligodendrocyte differentiation	GO:0048713	23	0.178
innate immune response	GO:0045087	157	0.178	Fly
positive regulation of programmed cell death	GO:0043068	218	0.176	Mouse
regulation of cd8 positive alpha beta t cell extravasation	GO:2000449	3	0.174
muscle cell development	GO:0055001	133	0.174
organic cyclic compound catabolic process	GO:1901361	295	0.173
positive regulation of t cell costimulation	GO:2000525	2	0.171
positive regulation of cell cycle	GO:0045787	92	0.170
bone remodeling	GO:0046849	53	0.170	Mouse
aromatic compound catabolic process	GO:0019439	286	0.169
negative regulation of cell proliferation	GO:0008285	296	0.167
protein localization to nucleus	GO:0034504	121	0.165	Mouse
chemokine mediated signaling pathway	GO:0070098	17	0.164
negative regulation of immune system process	GO:0002683	209	0.164
regulation of neutrophil chemotaxis	GO:0090022	14	0.164
calcium ion transport into cytosol	GO:0060402	48	0.163
antimicrobial peptide production	GO:0002775	2	0.161
hair follicle development	GO:0001942	85	0.159	Mouse
syncytium formation	GO:0006949	43	0.157
blood vessel morphogenesis	GO:0048514	285	0.157
cytosolic calcium ion transport	GO:0060401	48	0.157
regulation of branching involved in salivary gland morphogenesis	GO:0060693	11	0.156	Mouse
regulation of multi organism process	GO:0043900	111	0.155	Mouse
monosaccharide transport	GO:0015749	58	0.155	Mouse
regulation of protein secretion	GO:0050708	82	0.154	Mouse
regulation of gliogenesis	GO:0014013	50	0.154
neutrophil differentiation	GO:0030223	3	0.154
growth involved in symbiotic interaction	GO:0044110	23	0.154	Mouse
cellular chemical homeostasis	GO:0055082	215	0.153
cellular response to cytokine stimulus	GO:0071345	189	0.153	Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002824	61	0.152	Mouse
regulation of fatty acid transport	GO:2000191	10	0.151	Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001239	26	0.151
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.150
negative regulation of endothelial cell migration	GO:0010596	4	0.149
cellular extravasation	GO:0045123	17	0.148	Mouse
regulation of inflammatory response to antigenic stimulus	GO:0002861	21	0.147	Mouse
cellular metal ion homeostasis	GO:0006875	151	0.147
neutrophil migration	GO:1990266	37	0.147
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.146
negative regulation of macrophage apoptotic process	GO:2000110	3	0.146
neuronal action potential	GO:0019228	54	0.144
cellular response to amino acid stimulus	GO:0071230	29	0.143	Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.143
myeloid leukocyte mediated immunity	GO:0002444	42	0.143
regulation of cytokine biosynthetic process	GO:0042035	59	0.142
bundle of his development	GO:0003166	4	0.142
dendritic cell chemotaxis	GO:0002407	7	0.141
regulation of t cell chemotaxis	GO:0010819	5	0.141
positive regulation of t cell receptor signaling pathway	GO:0050862	4	0.141
cell cell recognition	GO:0009988	44	0.140
regulation of apoptotic signaling pathway	GO:2001233	197	0.140
antibacterial peptide production	GO:0002778	2	0.138
nucleoside triphosphate metabolic process	GO:0009141	230	0.137
t cell selection	GO:0045058	34	0.135
antigen processing and presentation	GO:0019882	47	0.134
negative regulation of eosinophil degranulation	GO:0043310	1	0.133
syncytium formation by plasma membrane fusion	GO:0000768	42	0.133
regulation of t cell extravasation	GO:2000407	3	0.132
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.132	Mouse
glial cell differentiation	GO:0010001	131	0.132
leukocyte activation involved in immune response	GO:0002366	126	0.132	Mouse
regulation of membrane potential	GO:0042391	192	0.132
extrinsic apoptotic signaling pathway via death domain receptors	GO:0008625	34	0.132	Mouse
ameboidal type cell migration	GO:0001667	128	0.129
positive regulation of jun kinase activity	GO:0043507	30	0.129	Mouse
helper t cell chemotaxis	GO:0035704	1	0.128
regulation of cellular component biogenesis	GO:0044087	181	0.128
endocytosis	GO:0006897	168	0.127	Fly
divalent inorganic cation transport	GO:0072511	178	0.126
regulation of jun kinase activity	GO:0043506	40	0.126	Mouse
forebrain cell migration	GO:0021885	58	0.125
cellular nitrogen compound catabolic process	GO:0044270	280	0.124
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.123	Mouse
positive regulation of antibacterial peptide biosynthetic process	GO:0006963	1	0.123
regulation of striated muscle cell differentiation	GO:0051153	81	0.121
immune complex clearance by monocytes and macrophages	GO:0002436	2	0.120
antimicrobial peptide biosynthetic process	GO:0002777	2	0.120
thymic t cell selection	GO:0045061	22	0.119
myelination	GO:0042552	74	0.119
sensory perception	GO:0007600	245	0.118
regulation of nucleotide metabolic process	GO:0006140	169	0.118
positive regulation of prostaglandin secretion	GO:0032308	5	0.118	Mouse
regulation of corticotropin releasing hormone secretion	GO:0043397	2	0.117	Mouse
purine nucleoside metabolic process	GO:0042278	241	0.116
organophosphate catabolic process	GO:0046434	232	0.115
cerebral cortex development	GO:0021987	86	0.115
alpha beta t cell differentiation	GO:0046632	69	0.115
regulation of protein localization to nucleus	GO:1900180	60	0.114	Mouse
positive regulation of stress activated mapk cascade	GO:0032874	48	0.114	Mouse
ribose phosphate metabolic process	GO:0019693	291	0.114
dendritic cell differentiation	GO:0097028	26	0.113
negative regulation of signal transduction in absence of ligand	GO:1901099	16	0.113
anion transport	GO:0006820	177	0.113	Mouse
response to molecule of bacterial origin	GO:0002237	143	0.112	Mouse
positive regulation of gtp catabolic process	GO:0033126	85	0.112
positive regulation of adaptive immune response	GO:0002821	61	0.112	Mouse
protein maturation	GO:0051604	176	0.111	Mouse
positive regulation of cell adhesion	GO:0045785	80	0.111
t cell proliferation	GO:0042098	120	0.110
leukocyte migration	GO:0050900	124	0.110
regulation of innate immune response	GO:0045088	91	0.110
muscle tissue development	GO:0060537	308	0.110
dna recombination	GO:0006310	92	0.108	Mouse
protein processing	GO:0016485	163	0.108	Mouse
rap protein signal transduction	GO:0032486	3	0.108
t helper 17 cell chemotaxis	GO:0035705	1	0.108
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	36	0.107	Mouse
hexose transport	GO:0008645	56	0.107	Mouse
regulation of protein complex assembly	GO:0043254	83	0.106
positive regulation of glial cell differentiation	GO:0045687	21	0.105
purine nucleoside catabolic process	GO:0006152	205	0.104
establishment of protein localization to organelle	GO:0072594	118	0.104	Mouse
multicellular organismal signaling	GO:0035637	91	0.104
nucleoside phosphate metabolic process	GO:0006753	338	0.104
regulation of b cell differentiation	GO:0045577	23	0.104
purine ribonucleoside metabolic process	GO:0046128	241	0.103
cellular response to molecule of bacterial origin	GO:0071219	83	0.103	Mouse
regulation of tumor necrosis factor production	GO:0032680	49	0.103
positive regulation of hair follicle development	GO:0051798	6	0.102	Mouse
myeloid leukocyte differentiation	GO:0002573	119	0.102	Mouse
positive regulation of myeloid cell differentiation	GO:0045639	43	0.101	Mouse
nucleoside triphosphate catabolic process	GO:0009143	205	0.101
regulation of t cell activation	GO:0050863	170	0.101
regulation of eosinophil degranulation	GO:0043309	1	0.101
regulation of inflammatory response	GO:0050727	147	0.100	Mouse
purine ribonucleoside catabolic process	GO:0046130	205	0.100
mammary gland epithelial cell proliferation	GO:0033598	24	0.099	Mouse
regulation of ion transport	GO:0043269	215	0.099	Mouse
regulation of glial cell differentiation	GO:0045685	41	0.098
multicellular organismal homeostasis	GO:0048871	164	0.098	Mouse
ribonucleoside metabolic process	GO:0009119	245	0.097
muscle fiber development	GO:0048747	76	0.097
natural killer cell differentiation	GO:0001779	21	0.097
carbohydrate derivative catabolic process	GO:1901136	231	0.096
monocyte extravasation	GO:0035696	2	0.096
hematopoietic stem cell migration	GO:0035701	1	0.095
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.095
heterocycle catabolic process	GO:0046700	280	0.095
regulation of regulated secretory pathway	GO:1903305	20	0.095
positive regulation of nucleoside metabolic process	GO:0045979	91	0.095
immune response activating signal transduction	GO:0002757	116	0.094
positive regulation of secretion	GO:0051047	130	0.094	Mouse
regulation of immunological synapse formation	GO:2000520	2	0.093
regulation of myoblast differentiation	GO:0045661	29	0.093
regulation of myeloid leukocyte mediated immunity	GO:0002886	25	0.093
lymphocyte differentiation	GO:0030098	242	0.092	Mouse
regulation of lymphocyte proliferation	GO:0050670	117	0.091
cellular response to lipid	GO:0071396	145	0.091	Mouse
positive regulation of tumor necrosis factor production	GO:0032760	30	0.091
protein import	GO:0017038	101	0.091	Mouse
modulation of growth of symbiont involved in interaction with host	GO:0044144	19	0.090	Mouse
acid secretion	GO:0046717	33	0.089	Mouse
regulation of lymphocyte mediated immunity	GO:0002706	84	0.089	Mouse
epithelial cell proliferation	GO:0050673	174	0.089	Mouse
positive regulation of immune complex clearance by monocytes and macrophages	GO:0090265	2	0.089
reactive oxygen species metabolic process	GO:0072593	84	0.089	Mouse
regulation of cell division	GO:0051302	76	0.088
nucleobase containing small molecule metabolic process	GO:0055086	352	0.088
regulation of epidermis development	GO:0045682	33	0.088	Mouse
response to organonitrogen compound	GO:0010243	246	0.087	Mouse
nuclear transport	GO:0051169	139	0.087	Mouse
regulation of action potential	GO:0098900	4	0.087
organic acid transport	GO:0015849	101	0.087	Mouse
positive regulation of immune effector process	GO:0002699	107	0.086	Mouse
cytokine mediated signaling pathway	GO:0019221	115	0.086	Mouse
striated muscle cell development	GO:0055002	125	0.086
regulation of type 2 immune response	GO:0002828	18	0.085
activation of jun kinase activity	GO:0007257	15	0.084	Mouse
carbohydrate metabolic process	GO:0005975	230	0.084	Mouse
telencephalon cell migration	GO:0022029	55	0.083
positive regulation of mapk cascade	GO:0043410	170	0.083	Mouse
positive regulation of gtpase activity	GO:0043547	85	0.083
positive regulation of lymphocyte migration	GO:2000403	11	0.083
myotube differentiation	GO:0014902	105	0.083
response to lipopolysaccharide	GO:0032496	128	0.082	Mouse
regulation of neutrophil migration	GO:1902622	14	0.082
cytokine metabolic process	GO:0042107	71	0.082
positive regulation of immunological synapse formation	GO:2000522	1	0.081
cellular response to biotic stimulus	GO:0071216	92	0.081	Mouse
positive regulation of syncytium formation by plasma membrane fusion	GO:0060143	17	0.081
positive regulation of glycoprotein metabolic process	GO:1903020	6	0.081
regulation of interferon gamma production	GO:0032649	57	0.081	Mouse
muscle system process	GO:0003012	141	0.081
glycoprotein biosynthetic process	GO:0009101	89	0.080
ribonucleotide catabolic process	GO:0009261	208	0.080
regulation of muscle tissue development	GO:1901861	97	0.080
endomembrane system organization	GO:0010256	147	0.080
ossification	GO:0001503	216	0.079	Mouse
cellular homeostasis	GO:0019725	240	0.079	Fly
dna metabolic process	GO:0006259	303	0.078	Mouse
cellular response to growth factor stimulus	GO:0071363	197	0.078
action potential	GO:0001508	78	0.078
lymphocyte costimulation	GO:0031294	15	0.078
temperature homeostasis	GO:0001659	26	0.077	Mouse
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.077
circadian rhythm	GO:0007623	114	0.077
signal transduction in absence of ligand	GO:0038034	55	0.076
amide transport	GO:0042886	138	0.076	Mouse
leukocyte proliferation	GO:0070661	172	0.076	Mouse
protein secretion	GO:0009306	111	0.076	Mouse
reactive nitrogen species metabolic process	GO:2001057	0	0.076
regulation of ion homeostasis	GO:2000021	64	0.075
regulation of gtp catabolic process	GO:0033124	113	0.075
defense response to bacterium	GO:0042742	119	0.075	Mouse Fly
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.075
interleukin 10 secretion	GO:0072608	4	0.074
negative regulation of fat cell differentiation	GO:0045599	36	0.074
g protein coupled receptor signaling pathway	GO:0007186	243	0.074
oligodendrocyte development	GO:0014003	20	0.074
forebrain development	GO:0030900	302	0.073
regulation of stress activated mapk cascade	GO:0032872	69	0.073	Mouse
t helper 1 cell differentiation	GO:0045063	13	0.073
positive regulation of t cell extravasation	GO:2000409	2	0.073
respiratory system development	GO:0060541	190	0.073
antibacterial humoral response	GO:0019731	8	0.073
regulation of cellular response to stress	GO:0080135	159	0.072	Mouse
t cell differentiation	GO:0030217	174	0.072
regulation of hormone levels	GO:0010817	211	0.072	Mouse
glycosyl compound catabolic process	GO:1901658	206	0.071
small gtpase mediated signal transduction	GO:0007264	97	0.071
necroptotic process	GO:0070266	21	0.070	Mouse
positive regulation of dendritic cell chemotaxis	GO:2000510	1	0.070
purine nucleotide catabolic process	GO:0006195	211	0.070
negative regulation of innate immune response	GO:0045824	17	0.070
cell type specific apoptotic process	GO:0097285	268	0.070
leukocyte chemotaxis	GO:0030595	69	0.069
cytokine secretion	GO:0050663	72	0.069
retinal cell programmed cell death	GO:0046666	8	0.069	Mouse
macrophage activation	GO:0042116	27	0.069
purine ribonucleotide catabolic process	GO:0009154	208	0.068
exocrine system development	GO:0035272	45	0.068	Mouse
positive regulation of jnk cascade	GO:0046330	46	0.068	Mouse
negative regulation of phosphatase activity	GO:0010923	5	0.068	Mouse
regulation of cellular catabolic process	GO:0031329	242	0.068
nucleotide metabolic process	GO:0009117	332	0.068
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	40	0.067
skeletal muscle organ development	GO:0060538	163	0.067
growth of symbiont in host	GO:0044117	23	0.067	Mouse
positive regulation of myotube differentiation	GO:0010831	24	0.066
carboxylic acid transport	GO:0046942	100	0.066	Mouse
alpha beta t cell activation	GO:0046631	91	0.065
protein targeting	GO:0006605	143	0.065	Mouse
exocytosis	GO:0006887	121	0.064
divalent inorganic cation homeostasis	GO:0072507	138	0.064	Mouse
antibacterial peptide biosynthetic process	GO:0002780	2	0.064
regulation of immunoglobulin mediated immune response	GO:0002889	37	0.063	Mouse
growth of symbiont involved in interaction with host	GO:0044116	23	0.063	Mouse
regulation of glucose transport	GO:0010827	32	0.063	Mouse
nucleotide catabolic process	GO:0009166	217	0.063
regulation of endopeptidase activity	GO:0052548	89	0.062	Mouse
cation homeostasis	GO:0055080	212	0.062	Mouse
purine containing compound metabolic process	GO:0072521	311	0.062
regulation of hematopoietic stem cell migration	GO:2000471	1	0.062
mucosal associated lymphoid tissue development	GO:0048537	12	0.062
single organismal cell cell adhesion	GO:0016337	131	0.062
regulation of response to wounding	GO:1903034	189	0.062	Mouse
regulation of myotube differentiation	GO:0010830	62	0.062
striated muscle tissue development	GO:0014706	293	0.062
tissue homeostasis	GO:0001894	115	0.061	Mouse
dendritic cell migration	GO:0036336	12	0.061
sequestering of metal ion	GO:0051238	19	0.061
posttranscriptional regulation of gene expression	GO:0010608	155	0.061	Mouse
axonogenesis	GO:0007409	274	0.061
molting cycle	GO:0042303	90	0.060	Mouse
regulation of immune complex clearance by monocytes and macrophages	GO:0090264	2	0.060
defense response to gram negative bacterium	GO:0050829	28	0.060	Fly
positive regulation of cellular amine metabolic process	GO:0033240	5	0.059
cation transport	GO:0006812	399	0.059
angiogenesis	GO:0001525	201	0.059
central nervous system neuron differentiation	GO:0021953	162	0.058
regulation of cell cycle	GO:0051726	281	0.058
mammary gland lobule development	GO:0061377	22	0.058	Mouse
guanosine containing compound catabolic process	GO:1901069	144	0.058
regulation of humoral immune response mediated by circulating immunoglobulin	GO:0002923	10	0.058	Mouse
positive regulation of antigen receptor mediated signaling pathway	GO:0050857	9	0.057
regulation of proteolysis	GO:0030162	164	0.057	Mouse
positive regulation of map kinase activity	GO:0043406	84	0.057	Mouse
heart morphogenesis	GO:0003007	178	0.056
regulation of interleukin 2 production	GO:0032663	28	0.056
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.056	Mouse
positive regulation of hormone secretion	GO:0046887	38	0.055	Mouse
regulation of tumor necrosis factor superfamily cytokine production	GO:1903555	50	0.055
response to nutrient levels	GO:0031667	109	0.055
positive regulation of protein kinase activity	GO:0045860	144	0.055	Mouse
regulation of transcription factor import into nucleus	GO:0042990	24	0.055	Mouse
defense response to virus	GO:0051607	68	0.055
purine containing compound catabolic process	GO:0072523	213	0.055
muscle cell differentiation	GO:0042692	261	0.055
regulation of protein import into nucleus	GO:0042306	52	0.054	Mouse
regulation of myeloid cell differentiation	GO:0045637	96	0.054	Mouse
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.054
positive regulation of peptide hormone secretion	GO:0090277	31	0.053	Mouse
ribonucleotide metabolic process	GO:0009259	291	0.053
cellular response to tumor necrosis factor	GO:0071356	21	0.052	Mouse
cell activation involved in immune response	GO:0002263	126	0.052	Mouse
positive regulation of hematopoietic stem cell migration	GO:2000473	1	0.052
regulation of prostaglandin secretion	GO:0032306	5	0.052	Mouse
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.052
purine nucleotide metabolic process	GO:0006163	302	0.052
negative regulation of alkaline phosphatase activity	GO:0010693	3	0.052	Mouse
regulation of secretion	GO:0051046	274	0.051	Mouse
response to organic cyclic compound	GO:0014070	198	0.051
interleukin 18 production	GO:0032621	4	0.051
regulation of angiogenesis	GO:0045765	81	0.051

Tnfsf14 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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